1YQ7A

Human farnesyl diphosphate synthase complexed with risedronate
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
337
structure length
334
Chain Sequence
EKQDFVQHFSQIVRVLTEDEPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthetase
publication title Human farnesyl diphosphate complexed with clinical inhibitor risedronate
rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 131
structure length 334
sequence length 337
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-02-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yq7A00
3APZA 5AHUB 4GA3A 4MC8A 5E8HA 3V66A 4Q23A 5IKHA 3VJCA 4H5DF 2E8UA 3KBKA 4DWBA 3ID0A 3QKCA 2I19A 1FPSA 5I1UA 3WEGA 1V4KA 4LZ0A 5ERNA 3P41A 3RBMA 4F6VA 1N1ZA 4LPGF 4OGUA 4LUUA 5HNAA 5ILKA 5DJVF 5DHKA 5B0IA 3IBAA 3ZMCA 2FTZA 3DYFA 5A0KA 2J5CA 3N46F 4KQUA 4DWGA 4MC3A 2ONHA 1YYUA 2VF6A 2F8ZF 5IMIA 5DIQF 3OACA 3LEEA 4WK5A 3WCIA 5AYPA 5A0IA 2ZCOA 4DEMF 1UBWA 4LPHF 5EAUA 3WCFA 1JFGA 5AELA 2F7MF 3SDVA 2J1PA 3ADZA 5DGSF 4ZQ8A 3UCAA 2F92F 3PYAA 4P0VA 2P1CA 3WCLA 3WCAA 5C05A 4JZBA 3SDQA 4DI5A 4XQRF 5AFXA 3N0GA 1RTRA 4LIXA 3P8RA 3KRCA 2F89F 5DHIA 3Q1OA 1EZFA 1WL1A 1YYTA 3AE0A 1YHLA 2E8WA 2H8OA 4NUAA 3TC1A 3LSNA 5JUZF 3WJNA 5ER8A 2QISA 3ASXA 5CG6A 3LVSA 5EROA 3WCHA 4XQSF 1VG7A 5B0JA 3KRFA 4LZ3A 2F8CF 3S4JA 1YQ7A 1V4HA 1UBYA 2J1OA 4LZCA 3EGTA 3MZVA 3WCMA 5DJPF 1WMWA 3AQCB 2E8VA 4LFVF 3DYGA 3ZOUA 3WCEA 2E8TA 2ZCQA 5CG5A 3WJKA 2E92A 2ZY1A 4OMHA 1WL3A 1HM4A 1YYRA 4NFIF 4PVYF 4L2XF 3VJAA 1VG2A 3B7LA 5E8LA 5DGMF 3PKOA 2DH4A 3KB9A 4QPFA 3N49F 2OPNA 1KIZA 2PS6A 3LGKA 4P0WA 5IL8A 5IN8A 3N3LF 4KWDA 4KQ5A 3WEHA 3TFVA 1VG6A 2E90A 3N0FA 4RYPA 5DJRF 4F62A 4FJQA 2PS5A 4KUXA 4N1ZF 4KKMA 4RXCA 3NPKA 3AQ0A 1N24A 2Q80A 4E9ZA 3EFQA 1N20A 3ZMBA 4F6XA 1YHKA 1HM7A 5B0MA 5ILZA 4HD1A 2AZJA 3NRIA 3RYWA 4LLSA 4H5CF 4LTZA 4LXWA 1WY0A 4OMGA 2Q58A 4RNQA 3WEIA 2O1OA 3WSBA 3ICKA 3M01A 4QXSF 1YHMA 2F9KF 3LG5A 3N5HF 1ZW5A 1YYQA 3OABA 3RYEA 3N1WF 1N23A 5DGNF 4JXYA 3S9VA 5IKAA 1DI1A 4NFKF 3TFPA 2Q9YA 1HXGA 2Z4VA 3LZ9A 4JYXA 3WCGA 1DGPA 2PS7A 2FORA 1RQIA 4KQSA 3BNXA 3PDEA 2Z4WA 5IVGA 4GP2A 3KRPA 3TS7A 1JFAA 5JV2F 2RAHA 4JVJF 5ILHA 3KROA 3VJ8A 4E9UA 3SDTA 3OACB 3W7FA 3TFNA 2E95A 3WCDA 5JV0F 5H9DA 3M00A 4RXDA 4DHDA 3Q30A 3G4FA 5B0KA 4KFAA 2E91A 5JV1F 4LFGA 4LA5A 4DXJA 1YJ4A 1WL2A 4N9UA 3CP6A 3LLWA 2AETA 2PS8A 2ONGA 2Q9ZA 3KRCB 3LJIA 5A0JA 3M02A 1V4EA 5ILIA 3WEKA 2E4OA 1VG3A 3VJBA 3WCJA 5B02A 2Z78A 4NKFA 3ACWA 5E8KA 4RXEA 5JA0F 2Z4ZA 3AQBB 5IK0A 5B01A 1UBVA 2Z7HA 1N1BA 3N1VF 3N5JF 2Z52A 3KROB 5IK9A 4LFEA 4E1EA 4LTVA 2Z7IA 3KRFB 3RMGA 3WC9A 5ILYA 1WL0A 3SDRA 3ICMA 3SAEA 5DW7A 1V4JA 5B0LA 4KVDA 3WCBA 4KVWA 2AEKA 4NG6A 5ILJA 2OA6A 4NFJF 3ICZA 3KRAA 4KPJA 1HX9A 4UMJA 3CC9A 3VJDA 1PS1A 3PH7A 1HXCA 3LDWA 2ZCSA 5HN7A 3VJ9A 3LGZB 4OKZA 3Q2ZA 1UBXA 4GP1A 2OPMA 1WKZA 3N3DA 3OYRA 3ZCDA 1RQJA 3P5RA 1YV5A 4P0XA 4EA2A 3NF2A 3WCCA 4PVXF 3WSAA 3ZL6A 3EZ3A 3WJOA 4EA1A 3MAVA 3CKEA 4KVIA 2E94A 3ACXA 4LLTA 5ERMA 2Z4XA 3M9UA 5IK6A 2Z50A 1N22A 3QQVA 2PS4A 3ICNA 3WEJA 5HN9A 3LOMA 3V1VA 4MC0A 2ZEVA 2AZKA 3DYHA 3M0GA 3V1XA 3KRAB 5EASA 3Q2QA 4KVYA 1VG4A 4NKEA 4KK2A 5IL3A 4GAXA 4FP4A 5B00A 4JZXA 2AZLA 4OKMA 4RXAA 1N21A 2E8XA 5IMPA 4LOBA 3IPIA 3LK5A 4XQTF 1KIYA 1YYSA 5B03A 3P8LA 4KPDA 3ACYA 3SDUA 3G4DA 3N45F 3BNYA 5EATA 4LA6A 4JXNA 3WEFA 5KSXF 2AELA 3LMDA 3OABB 5DZ2A 5ILDA 4K10A 3VJEA 5HN8A 2ZEUA 4DZWA 2ZCRA 2Z4YA 2EWGA 1HXAA 2OGDA 3NPRA 4EA0A 5IM1A 4H5EF 2F94F 5IMNA 3N6KF 1V4IA 3KRPB 3PYBA 3P5PA 3WE9A 2E93A
chains in the Genus database with same CATH superfamily
3APZA 5AHUB 4GA3A 4MC8A 5E8HA 3V66A 4Q23A 5IKHA 3VJCA 4H5DF 2E8UA 3KBKA 4DWBA 3ID0A 3QKCA 2I19A 1FPSA 5I1UA 3WEGA 1V4KA 4LZ0A 5ERNA 3P41A 3RBMA 4F6VA 1N1ZA 4LPGF 4OGUA 4LUUA 5HNAA 5ILKA 5DJVF 5DHKA 5B0IA 3IBAA 3ZMCA 2FTZA 3DYFA 5A0KA 2J5CA 3N46F 4KQUA 4DWGA 4MC3A 2ONHA 1YYUA 2VF6A 2F8ZF 5IMIA 5DIQF 3OACA 3LEEA 4WK5A 3WCIA 5AYPA 5A0IA 2ZCOA 4DEMF 1UBWA 4LPHF 5EAUA 3WCFA 1JFGA 5AELA 2F7MF 3SDVA 2J1PA 3ADZA 5DGSF 4ZQ8A 3UCAA 2F92F 3PYAA 4P0VA 2P1CA 3WCLA 3WCAA 5C05A 4JZBA 3SDQA 4DI5A 4XQRF 5AFXA 3N0GA 1RTRA 4LIXA 3P8RA 3KRCA 2F89F 5DHIA 3Q1OA 1EZFA 1WL1A 1YYTA 3AE0A 1YHLA 2E8WA 2H8OA 4NUAA 3TC1A 3LSNA 5JUZF 3WJNA 5ER8A 2QISA 3ASXA 5CG6A 3LVSA 5EROA 3WCHA 4XQSF 1VG7A 5B0JA 3KRFA 4LZ3A 2F8CF 3S4JA 1YQ7A 1V4HA 1UBYA 2J1OA 4LZCA 3EGTA 3MZVA 3WCMA 5DJPF 1WMWA 3AQCB 2E8VA 4LFVF 3DYGA 3ZOUA 3WCEA 2E8TA 2ZCQA 5CG5A 3WJKA 2E92A 2ZY1A 4OMHA 1WL3A 1HM4A 1YYRA 4NFIF 4PVYF 4L2XF 3VJAA 1VG2A 3B7LA 5E8LA 5DGMF 3PKOA 2DH4A 3KB9A 4QPFA 3N49F 2OPNA 1KIZA 2PS6A 3LGKA 4P0WA 5IL8A 5IN8A 3N3LF 4KWDA 4KQ5A 3WEHA 3TFVA 1VG6A 2E90A 3N0FA 4RYPA 5DJRF 4F62A 4FJQA 2PS5A 4KUXA 4N1ZF 4KKMA 4RXCA 3NPKA 3AQ0A 1N24A 2Q80A 4E9ZA 3EFQA 1N20A 3ZMBA 4F6XA 1YHKA 1HM7A 5B0MA 5ILZA 4HD1A 2AZJA 3NRIA 3RYWA 4LLSA 4H5CF 4LTZA 4LXWA 1WY0A 4OMGA 2Q58A 4RNQA 3WEIA 2O1OA 3WSBA 3ICKA 3M01A 4QXSF 1YHMA 2F9KF 3LG5A 3N5HF 1ZW5A 1YYQA 3OABA 3RYEA 3N1WF 1N23A 5DGNF 4JXYA 3S9VA 5IKAA 1DI1A 4NFKF 3TFPA 2Q9YA 1HXGA 2Z4VA 3LZ9A 4JYXA 3WCGA 1DGPA 2PS7A 2FORA 1RQIA 4KQSA 3BNXA 3PDEA 2Z4WA 5IVGA 4GP2A 3KRPA 3TS7A 1JFAA 5JV2F 2RAHA 4JVJF 5ILHA 3KROA 3VJ8A 4E9UA 3SDTA 3OACB 3W7FA 3TFNA 2E95A 3WCDA 5JV0F 5H9DA 3M00A 4RXDA 4DHDA 3Q30A 3G4FA 5B0KA 4KFAA 2E91A 5JV1F 4LFGA 4LA5A 4DXJA 1YJ4A 1WL2A 4N9UA 3CP6A 3LLWA 2AETA 2PS8A 2ONGA 2Q9ZA 3KRCB 3LJIA 5A0JA 3M02A 1V4EA 5ILIA 3WEKA 2E4OA 1VG3A 3VJBA 3WCJA 5B02A 2Z78A 4NKFA 3ACWA 5E8KA 4RXEA 5JA0F 2Z4ZA 3AQBB 5IK0A 5B01A 1UBVA 2Z7HA 1N1BA 3N1VF 3N5JF 2Z52A 3KROB 5IK9A 4LFEA 4E1EA 4LTVA 2Z7IA 3KRFB 3RMGA 3WC9A 5ILYA 1WL0A 3SDRA 3ICMA 3SAEA 5DW7A 1V4JA 5B0LA 4KVDA 3WCBA 4KVWA 2AEKA 4NG6A 5ILJA 2OA6A 4NFJF 3ICZA 3KRAA 4KPJA 1HX9A 4UMJA 3CC9A 3VJDA 1PS1A 3PH7A 1HXCA 3LDWA 2ZCSA 5HN7A 3VJ9A 3LGZB 4OKZA 3Q2ZA 1UBXA 4GP1A 2OPMA 1WKZA 3N3DA 3OYRA 3ZCDA 1RQJA 3P5RA 1YV5A 4P0XA 4EA2A 3NF2A 3WCCA 4PVXF 3WSAA 3ZL6A 3EZ3A 3WJOA 4EA1A 3MAVA 3CKEA 4KVIA 2E94A 3ACXA 4LLTA 5ERMA 2Z4XA 3M9UA 5IK6A 2Z50A 1N22A 3QQVA 2PS4A 3ICNA 3WEJA 5HN9A 3LOMA 3V1VA 4MC0A 2ZEVA 2AZKA 3DYHA 3M0GA 3V1XA 3KRAB 5EASA 3Q2QA 4KVYA 1VG4A 4NKEA 4KK2A 5IL3A 4GAXA 4FP4A 5B00A 4JZXA 2AZLA 4OKMA 4RXAA 1N21A 2E8XA 5IMPA 4LOBA 3IPIA 3LK5A 4XQTF 1KIYA 1YYSA 5B03A 3P8LA 4KPDA 3ACYA 3SDUA 3G4DA 3N45F 3BNYA 5EATA 4LA6A 4JXNA 3WEFA 5KSXF 2AELA 3LMDA 3OABB 5DZ2A 5ILDA 4K10A 3VJEA 5HN8A 2ZEUA 4DZWA 2ZCRA 2Z4YA 2EWGA 1HXAA 2OGDA 3NPRA 4EA0A 5IM1A 4H5EF 2F94F 5IMNA 3N6KF 1V4IA 3KRPB 3PYBA 3P5PA 3WE9A 2E93A
chains in the Genus database with same CATH topology
3APZA 5AHUB 4GA3A 4MC8A 5E8HA 3V66A 4Q23A 5IKHA 3VJCA 4H5DF 2E8UA 3KBKA 4DWBA 3ID0A 3QKCA 2I19A 1FPSA 5I1UA 3WEGA 1V4KA 4LZ0A 5ERNA 3P41A 3RBMA 4F6VA 1N1ZA 4LPGF 4OGUA 4LUUA 5HNAA 5ILKA 5DJVF 5DHKA 5B0IA 3IBAA 3ZMCA 2FTZA 3DYFA 5A0KA 2J5CA 3N46F 4KQUA 4DWGA 4MC3A 2ONHA 1YYUA 2VF6A 2F8ZF 5IMIA 5DIQF 3OACA 3LEEA 4WK5A 3WCIA 5AYPA 5A0IA 2ZCOA 4DEMF 1UBWA 4LPHF 5EAUA 3WCFA 1JFGA 5AELA 2F7MF 3SDVA 2J1PA 3ADZA 5DGSF 4ZQ8A 3UCAA 2F92F 3PYAA 4P0VA 2P1CA 3WCLA 3WCAA 5C05A 4JZBA 3SDQA 4DI5A 4XQRF 5AFXA 3N0GA 1RTRA 4LIXA 3P8RA 3KRCA 2F89F 5DHIA 3Q1OA 1EZFA 1WL1A 1YYTA 3AE0A 1YHLA 2E8WA 2H8OA 4NUAA 3TC1A 3LSNA 5JUZF 3WJNA 5ER8A 2QISA 3ASXA 5CG6A 3LVSA 5EROA 3WCHA 4XQSF 1VG7A 5B0JA 3KRFA 4LZ3A 2F8CF 3S4JA 1YQ7A 1V4HA 1UBYA 2J1OA 4LZCA 3EGTA 3MZVA 3WCMA 5DJPF 1WMWA 3AQCB 2E8VA 4LFVF 3DYGA 3ZOUA 3WCEA 2E8TA 2ZCQA 5CG5A 3WJKA 2E92A 2ZY1A 4OMHA 1WL3A 1HM4A 1YYRA 4NFIF 4PVYF 4L2XF 3VJAA 1VG2A 3B7LA 5E8LA 5DGMF 3PKOA 2DH4A 3KB9A 4QPFA 3N49F 2OPNA 1KIZA 2PS6A 3LGKA 4P0WA 5IL8A 5IN8A 3N3LF 4KWDA 4KQ5A 3WEHA 3TFVA 1VG6A 2E90A 3N0FA 4RYPA 5DJRF 4F62A 4FJQA 2PS5A 4KUXA 4N1ZF 4KKMA 4RXCA 3NPKA 3AQ0A 1N24A 2Q80A 4E9ZA 3EFQA 1N20A 3ZMBA 4F6XA 1YHKA 1HM7A 5B0MA 5ILZA 4HD1A 2AZJA 3NRIA 3RYWA 4LLSA 4H5CF 4LTZA 4LXWA 1WY0A 4OMGA 2Q58A 4RNQA 3WEIA 2O1OA 3WSBA 3ICKA 3M01A 4QXSF 1YHMA 2F9KF 3LG5A 3N5HF 1ZW5A 1YYQA 3OABA 3RYEA 3N1WF 1N23A 5DGNF 4JXYA 3S9VA 5IKAA 1DI1A 4NFKF 3TFPA 2Q9YA 1HXGA 2Z4VA 3LZ9A 4JYXA 3WCGA 1DGPA 2PS7A 2FORA 1RQIA 4KQSA 3BNXA 3PDEA 2Z4WA 5IVGA 4GP2A 3KRPA 3TS7A 1JFAA 5JV2F 2RAHA 4JVJF 5ILHA 3KROA 3VJ8A 4E9UA 3SDTA 3OACB 3W7FA 3TFNA 2E95A 3WCDA 5JV0F 5H9DA 3M00A 4RXDA 4DHDA 3Q30A 3G4FA 5B0KA 4KFAA 2E91A 5JV1F 4LFGA 4LA5A 4DXJA 1YJ4A 1WL2A 4N9UA 3CP6A 3LLWA 2AETA 2PS8A 2ONGA 2Q9ZA 3KRCB 3LJIA 5A0JA 3M02A 1V4EA 5ILIA 3WEKA 2E4OA 1VG3A 3VJBA 3WCJA 5B02A 2Z78A 4NKFA 3ACWA 5E8KA 4RXEA 5JA0F 2Z4ZA 3AQBB 5IK0A 5B01A 1UBVA 2Z7HA 1N1BA 3N1VF 3N5JF 2Z52A 3KROB 5IK9A 4LFEA 4E1EA 4LTVA 2Z7IA 3KRFB 3RMGA 3WC9A 5ILYA 1WL0A 3SDRA 3ICMA 3SAEA 5DW7A 1V4JA 5B0LA 4KVDA 3WCBA 4KVWA 2AEKA 4NG6A 5ILJA 2OA6A 4NFJF 3ICZA 3KRAA 4KPJA 1HX9A 4UMJA 3CC9A 3VJDA 1PS1A 3PH7A 1HXCA 3LDWA 2ZCSA 5HN7A 3VJ9A 3LGZB 4OKZA 3Q2ZA 1UBXA 4GP1A 2OPMA 1WKZA 3N3DA 3OYRA 3ZCDA 1RQJA 3P5RA 1YV5A 4P0XA 4EA2A 3NF2A 3WCCA 4PVXF 3WSAA 3ZL6A 3EZ3A 3WJOA 4EA1A 3MAVA 3CKEA 4KVIA 2E94A 3ACXA 4LLTA 5ERMA 2Z4XA 3M9UA 5IK6A 2Z50A 1N22A 3QQVA 2PS4A 3ICNA 3WEJA 5HN9A 3LOMA 3V1VA 4MC0A 2ZEVA 2AZKA 3DYHA 3M0GA 3V1XA 3KRAB 5EASA 3Q2QA 4KVYA 1VG4A 4NKEA 4KK2A 5IL3A 4GAXA 4FP4A 5B00A 4JZXA 2AZLA 4OKMA 4RXAA 1N21A 2E8XA 5IMPA 4LOBA 3IPIA 3LK5A 4XQTF 1KIYA 1YYSA 5B03A 3P8LA 4KPDA 3ACYA 3SDUA 3G4DA 3N45F 3BNYA 5EATA 4LA6A 4JXNA 3WEFA 5KSXF 2AELA 3LMDA 3OABB 5DZ2A 5ILDA 4K10A 3VJEA 5HN8A 2ZEUA 4DZWA 2ZCRA 2Z4YA 2EWGA 1HXAA 2OGDA 3NPRA 4EA0A 5IM1A 4H5EF 2F94F 5IMNA 3N6KF 1V4IA 3KRPB 3PYBA 3P5PA 3WE9A 2E93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3APZ A;  5AHU B;  4GA3 A;  4MC8 A;  5E8H A;  3V66 A;  4Q23 A;  5IKH A;  3VJC A;  4H5D F;  2E8U A;  3KBK A;  4DWB A;  3ID0 A;  3QKC A;  2I19 A;  1FPS A;  5I1U A;  3WEG A;  1V4K A;  4LZ0 A;  5ERN A;  3P41 A;  3RBM A;  4F6V A;  1N1Z A;  4LPG F;  4OGU A;  4LUU A;  5HNA A;  5ILK A;  5DJV F;  5DHK A;  5B0I A;  3IBA A;  3ZMC A;  2FTZ A;  3DYF A;  5A0K A;  2J5C A;  3N46 F;  4KQU A;  4DWG A;  4MC3 A;  2ONH A;  1YYU A;  2VF6 A;  2F8Z F;  5IMI A;  5DIQ F;  3OAC A;  3LEE A;  4WK5 A;  3WCI A;  5AYP A;  5A0I A;  2ZCO A;  4DEM F;  1UBW A;  4LPH F;  5EAU A;  3WCF A;  1JFG A;  5AEL A;  2F7M F;  3SDV A;  2J1P A;  3ADZ A;  5DGS F;  4ZQ8 A;  3UCA A;  2F92 F;  3PYA A;  4P0V A;  2P1C A;  3WCL A;  3WCA A;  5C05 A;  4JZB A;  3SDQ A;  4DI5 A;  4XQR F;  5AFX A;  3N0G A;  1RTR A;  4LIX A;  3P8R A;  3KRC A;  2F89 F;  5DHI A;  3Q1O A;  1EZF A;  1WL1 A;  1YYT A;  3AE0 A;  1YHL A;  2E8W A;  2H8O A;  4NUA A;  3TC1 A;  3LSN A;  5JUZ F;  3WJN A;  5ER8 A;  2QIS A;  3ASX A;  5CG6 A;  3LVS A;  5ERO A;  3WCH A;  4XQS F;  1VG7 A;  5B0J A;  3KRF A;  4LZ3 A;  2F8C F;  3S4J A;  1YQ7 A;  1V4H A;  1UBY A;  2J1O A;  4LZC A;  3EGT A;  3MZV A;  3WCM A;  5DJP F;  1WMW A;  3AQC B;  2E8V A;  4LFV F;  3DYG A;  3ZOU A;  3WCE A;  2E8T A;  2ZCQ A;  5CG5 A;  3WJK A;  2E92 A;  2ZY1 A;  4OMH A;  1WL3 A;  1HM4 A;  1YYR A;  4NFI F;  4PVY F;  4L2X F;  3VJA A;  1VG2 A;  3B7L A;  5E8L A;  5DGM F;  3PKO A;  2DH4 A;  3KB9 A;  4QPF A;  3N49 F;  2OPN A;  1KIZ A;  2PS6 A;  3LGK A;  4P0W A;  5IL8 A;  5IN8 A;  3N3L F;  4KWD A;  4KQ5 A;  3WEH A;  3TFV A;  1VG6 A;  2E90 A;  3N0F A;  4RYP A;  5DJR F;  4F62 A;  4FJQ A;  2PS5 A;  4KUX A;  4N1Z F;  4KKM A;  4RXC A;  3NPK A;  3AQ0 A;  1N24 A;  2Q80 A;  4E9Z A;  3EFQ A;  1N20 A;  3ZMB A;  4F6X A;  1YHK A;  1HM7 A;  5B0M A;  5ILZ A;  4HD1 A;  2AZJ A;  3NRI A;  3RYW A;  4LLS A;  4H5C F;  4LTZ A;  4LXW A;  1WY0 A;  4OMG A;  2Q58 A;  4RNQ A;  3WEI A;  2O1O A;  3WSB A;  3ICK A;  3M01 A;  4QXS F;  1YHM A;  2F9K F;  3LG5 A;  3N5H F;  1ZW5 A;  1YYQ A;  3OAB A;  3RYE A;  3N1W F;  1N23 A;  5DGN F;  4JXY A;  3S9V A;  5IKA A;  1DI1 A;  4NFK F;  3TFP A;  2Q9Y A;  1HXG A;  2Z4V A;  3LZ9 A;  4JYX A;  3WCG A;  1DGP A;  2PS7 A;  2FOR A;  1RQI A;  4KQS A;  3BNX A;  3PDE A;  2Z4W A;  5IVG A;  4GP2 A;  3KRP A;  3TS7 A;  1JFA A;  5JV2 F;  2RAH A;  4JVJ F;  5ILH A;  3KRO A;  3VJ8 A;  4E9U A;  3SDT A;  3OAC B;  3W7F A;  3TFN A;  2E95 A;  3WCD A;  5JV0 F;  5H9D A;  3M00 A;  4RXD A;  4DHD A;  3Q30 A;  3G4F A;  5B0K A;  4KFA A;  2E91 A;  5JV1 F;  4LFG A;  4LA5 A;  4DXJ A;  1YJ4 A;  1WL2 A;  4N9U A;  3CP6 A;  3LLW A;  2AET A;  2PS8 A;  2ONG A;  2Q9Z A;  3KRC B;  3LJI A;  5A0J A;  3M02 A;  1V4E A;  5ILI A;  3WEK A;  2E4O A;  1VG3 A;  3VJB A;  3WCJ A;  5B02 A;  2Z78 A;  4NKF A;  3ACW A;  5E8K A;  4RXE A;  5JA0 F;  2Z4Z A;  3AQB B;  5IK0 A;  5B01 A;  1UBV A;  2Z7H A;  1N1B A;  3N1V F;  3N5J F;  2Z52 A;  3KRO B;  5IK9 A;  4LFE A;  4E1E A;  4LTV A;  2Z7I A;  3KRF B;  3RMG A;  3WC9 A;  5ILY A;  1WL0 A;  3SDR A;  3ICM A;  3SAE A;  5DW7 A;  1V4J A;  5B0L A;  4KVD A;  3WCB A;  4KVW A;  2AEK A;  4NG6 A;  5ILJ A;  2OA6 A;  4NFJ F;  3ICZ A;  3KRA A;  4KPJ A;  1HX9 A;  4UMJ A;  3CC9 A;  3VJD A;  1PS1 A;  3PH7 A;  1HXC A;  3LDW A;  2ZCS A;  5HN7 A;  3VJ9 A;  3LGZ B;  4OKZ A;  3Q2Z A;  1UBX A;  4GP1 A;  2OPM A;  1WKZ A;  3N3D A;  3OYR A;  3ZCD A;  1RQJ A;  3P5R A;  1YV5 A;  4P0X A;  4EA2 A;  3NF2 A;  3WCC A;  4PVX F;  3WSA A;  3ZL6 A;  3EZ3 A;  3WJO A;  4EA1 A;  3MAV A;  3CKE A;  4KVI A;  2E94 A;  3ACX A;  4LLT A;  5ERM A;  2Z4X A;  3M9U A;  5IK6 A;  2Z50 A;  1N22 A;  3QQV A;  2PS4 A;  3ICN A;  3WEJ A;  5HN9 A;  3LOM A;  3V1V A;  4MC0 A;  2ZEV A;  2AZK A;  3DYH A;  3M0G A;  3V1X A;  3KRA B;  5EAS A;  3Q2Q A;  4KVY A;  1VG4 A;  4NKE A;  4KK2 A;  5IL3 A;  4GAX A;  4FP4 A;  5B00 A;  4JZX A;  2AZL A;  4OKM A;  4RXA A;  1N21 A;  2E8X A;  5IMP A;  4LOB A;  3IPI A;  3LK5 A;  4XQT F;  1KIY A;  1YYS A;  5B03 A;  3P8L A;  4KPD A;  3ACY A;  3SDU A;  3G4D A;  3N45 F;  3BNY A;  5EAT A;  4LA6 A;  4JXN A;  3WEF A;  5KSX F;  2AEL A;  3LMD A;  3OAB B;  5DZ2 A;  5ILD A;  4K10 A;  3VJE A;  5HN8 A;  2ZEU A;  4DZW A;  2ZCR A;  2Z4Y A;  2EWG A;  1HXA A;  2OGD A;  3NPR A;  4EA0 A;  5IM1 A;  4H5E F;  2F94 F;  5IMN A;  3N6K F;  1V4I A;  3KRP B;  3PYB A;  3P5P A;  3WE9 A;  2E93 A; 
#chains in the Genus database with same CATH topology
 3APZ A;  5AHU B;  4GA3 A;  4MC8 A;  5E8H A;  3V66 A;  4Q23 A;  5IKH A;  3VJC A;  4H5D F;  2E8U A;  3KBK A;  4DWB A;  3ID0 A;  3QKC A;  2I19 A;  1FPS A;  5I1U A;  3WEG A;  1V4K A;  4LZ0 A;  5ERN A;  3P41 A;  3RBM A;  4F6V A;  1N1Z A;  4LPG F;  4OGU A;  4LUU A;  5HNA A;  5ILK A;  5DJV F;  5DHK A;  5B0I A;  3IBA A;  3ZMC A;  2FTZ A;  3DYF A;  5A0K A;  2J5C A;  3N46 F;  4KQU A;  4DWG A;  4MC3 A;  2ONH A;  1YYU A;  2VF6 A;  2F8Z F;  5IMI A;  5DIQ F;  3OAC A;  3LEE A;  4WK5 A;  3WCI A;  5AYP A;  5A0I A;  2ZCO A;  4DEM F;  1UBW A;  4LPH F;  5EAU A;  3WCF A;  1JFG A;  5AEL A;  2F7M F;  3SDV A;  2J1P A;  3ADZ A;  5DGS F;  4ZQ8 A;  3UCA A;  2F92 F;  3PYA A;  4P0V A;  2P1C A;  3WCL A;  3WCA A;  5C05 A;  4JZB A;  3SDQ A;  4DI5 A;  4XQR F;  5AFX A;  3N0G A;  1RTR A;  4LIX A;  3P8R A;  3KRC A;  2F89 F;  5DHI A;  3Q1O A;  1EZF A;  1WL1 A;  1YYT A;  3AE0 A;  1YHL A;  2E8W A;  2H8O A;  4NUA A;  3TC1 A;  3LSN A;  5JUZ F;  3WJN A;  5ER8 A;  2QIS A;  3ASX A;  5CG6 A;  3LVS A;  5ERO A;  3WCH A;  4XQS F;  1VG7 A;  5B0J A;  3KRF A;  4LZ3 A;  2F8C F;  3S4J A;  1YQ7 A;  1V4H A;  1UBY A;  2J1O A;  4LZC A;  3EGT A;  3MZV A;  3WCM A;  5DJP F;  1WMW A;  3AQC B;  2E8V A;  4LFV F;  3DYG A;  3ZOU A;  3WCE A;  2E8T A;  2ZCQ A;  5CG5 A;  3WJK A;  2E92 A;  2ZY1 A;  4OMH A;  1WL3 A;  1HM4 A;  1YYR A;  4NFI F;  4PVY F;  4L2X F;  3VJA A;  1VG2 A;  3B7L A;  5E8L A;  5DGM F;  3PKO A;  2DH4 A;  3KB9 A;  4QPF A;  3N49 F;  2OPN A;  1KIZ A;  2PS6 A;  3LGK A;  4P0W A;  5IL8 A;  5IN8 A;  3N3L F;  4KWD A;  4KQ5 A;  3WEH A;  3TFV A;  1VG6 A;  2E90 A;  3N0F A;  4RYP A;  5DJR F;  4F62 A;  4FJQ A;  2PS5 A;  4KUX A;  4N1Z F;  4KKM A;  4RXC A;  3NPK A;  3AQ0 A;  1N24 A;  2Q80 A;  4E9Z A;  3EFQ A;  1N20 A;  3ZMB A;  4F6X A;  1YHK A;  1HM7 A;  5B0M A;  5ILZ A;  4HD1 A;  2AZJ A;  3NRI A;  3RYW A;  4LLS A;  4H5C F;  4LTZ A;  4LXW A;  1WY0 A;  4OMG A;  2Q58 A;  4RNQ A;  3WEI A;  2O1O A;  3WSB A;  3ICK A;  3M01 A;  4QXS F;  1YHM A;  2F9K F;  3LG5 A;  3N5H F;  1ZW5 A;  1YYQ A;  3OAB A;  3RYE A;  3N1W F;  1N23 A;  5DGN F;  4JXY A;  3S9V A;  5IKA A;  1DI1 A;  4NFK F;  3TFP A;  2Q9Y A;  1HXG A;  2Z4V A;  3LZ9 A;  4JYX A;  3WCG A;  1DGP A;  2PS7 A;  2FOR A;  1RQI A;  4KQS A;  3BNX A;  3PDE A;  2Z4W A;  5IVG A;  4GP2 A;  3KRP A;  3TS7 A;  1JFA A;  5JV2 F;  2RAH A;  4JVJ F;  5ILH A;  3KRO A;  3VJ8 A;  4E9U A;  3SDT A;  3OAC B;  3W7F A;  3TFN A;  2E95 A;  3WCD A;  5JV0 F;  5H9D A;  3M00 A;  4RXD A;  4DHD A;  3Q30 A;  3G4F A;  5B0K A;  4KFA A;  2E91 A;  5JV1 F;  4LFG A;  4LA5 A;  4DXJ A;  1YJ4 A;  1WL2 A;  4N9U A;  3CP6 A;  3LLW A;  2AET A;  2PS8 A;  2ONG A;  2Q9Z A;  3KRC B;  3LJI A;  5A0J A;  3M02 A;  1V4E A;  5ILI A;  3WEK A;  2E4O A;  1VG3 A;  3VJB A;  3WCJ A;  5B02 A;  2Z78 A;  4NKF A;  3ACW A;  5E8K A;  4RXE A;  5JA0 F;  2Z4Z A;  3AQB B;  5IK0 A;  5B01 A;  1UBV A;  2Z7H A;  1N1B A;  3N1V F;  3N5J F;  2Z52 A;  3KRO B;  5IK9 A;  4LFE A;  4E1E A;  4LTV A;  2Z7I A;  3KRF B;  3RMG A;  3WC9 A;  5ILY A;  1WL0 A;  3SDR A;  3ICM A;  3SAE A;  5DW7 A;  1V4J A;  5B0L A;  4KVD A;  3WCB A;  4KVW A;  2AEK A;  4NG6 A;  5ILJ A;  2OA6 A;  4NFJ F;  3ICZ A;  3KRA A;  4KPJ A;  1HX9 A;  4UMJ A;  3CC9 A;  3VJD A;  1PS1 A;  3PH7 A;  1HXC A;  3LDW A;  2ZCS A;  5HN7 A;  3VJ9 A;  3LGZ B;  4OKZ A;  3Q2Z A;  1UBX A;  4GP1 A;  2OPM A;  1WKZ A;  3N3D A;  3OYR A;  3ZCD A;  1RQJ A;  3P5R A;  1YV5 A;  4P0X A;  4EA2 A;  3NF2 A;  3WCC A;  4PVX F;  3WSA A;  3ZL6 A;  3EZ3 A;  3WJO A;  4EA1 A;  3MAV A;  3CKE A;  4KVI A;  2E94 A;  3ACX A;  4LLT A;  5ERM A;  2Z4X A;  3M9U A;  5IK6 A;  2Z50 A;  1N22 A;  3QQV A;  2PS4 A;  3ICN A;  3WEJ A;  5HN9 A;  3LOM A;  3V1V A;  4MC0 A;  2ZEV A;  2AZK A;  3DYH A;  3M0G A;  3V1X A;  3KRA B;  5EAS A;  3Q2Q A;  4KVY A;  1VG4 A;  4NKE A;  4KK2 A;  5IL3 A;  4GAX A;  4FP4 A;  5B00 A;  4JZX A;  2AZL A;  4OKM A;  4RXA A;  1N21 A;  2E8X A;  5IMP A;  4LOB A;  3IPI A;  3LK5 A;  4XQT F;  1KIY A;  1YYS A;  5B03 A;  3P8L A;  4KPD A;  3ACY A;  3SDU A;  3G4D A;  3N45 F;  3BNY A;  5EAT A;  4LA6 A;  4JXN A;  3WEF A;  5KSX F;  2AEL A;  3LMD A;  3OAB B;  5DZ2 A;  5ILD A;  4K10 A;  3VJE A;  5HN8 A;  2ZEU A;  4DZW A;  2ZCR A;  2Z4Y A;  2EWG A;  1HXA A;  2OGD A;  3NPR A;  4EA0 A;  5IM1 A;  4H5E F;  2F94 F;  5IMN A;  3N6K F;  1V4I A;  3KRP B;  3PYB A;  3P5P A;  3WE9 A;  2E93 A; 
#chains in the Genus database with same CATH homology
 3APZ A;  5AHU B;  4GA3 A;  4MC8 A;  5E8H A;  3V66 A;  4Q23 A;  5IKH A;  3VJC A;  4H5D F;  2E8U A;  3KBK A;  4DWB A;  3ID0 A;  3QKC A;  2I19 A;  1FPS A;  5I1U A;  3WEG A;  1V4K A;  4LZ0 A;  5ERN A;  3P41 A;  3RBM A;  4F6V A;  1N1Z A;  4LPG F;  4OGU A;  4LUU A;  5HNA A;  5ILK A;  5DJV F;  5DHK A;  5B0I A;  3IBA A;  3ZMC A;  2FTZ A;  3DYF A;  5A0K A;  2J5C A;  3N46 F;  4KQU A;  4DWG A;  4MC3 A;  2ONH A;  1YYU A;  2VF6 A;  2F8Z F;  5IMI A;  5DIQ F;  3OAC A;  3LEE A;  4WK5 A;  3WCI A;  5AYP A;  5A0I A;  2ZCO A;  4DEM F;  1UBW A;  4LPH F;  5EAU A;  3WCF A;  1JFG A;  5AEL A;  2F7M F;  3SDV A;  2J1P A;  3ADZ A;  5DGS F;  4ZQ8 A;  3UCA A;  2F92 F;  3PYA A;  4P0V A;  2P1C A;  3WCL A;  3WCA A;  5C05 A;  4JZB A;  3SDQ A;  4DI5 A;  4XQR F;  5AFX A;  3N0G A;  1RTR A;  4LIX A;  3P8R A;  3KRC A;  2F89 F;  5DHI A;  3Q1O A;  1EZF A;  1WL1 A;  1YYT A;  3AE0 A;  1YHL A;  2E8W A;  2H8O A;  4NUA A;  3TC1 A;  3LSN A;  5JUZ F;  3WJN A;  5ER8 A;  2QIS A;  3ASX A;  5CG6 A;  3LVS A;  5ERO A;  3WCH A;  4XQS F;  1VG7 A;  5B0J A;  3KRF A;  4LZ3 A;  2F8C F;  3S4J A;  1YQ7 A;  1V4H A;  1UBY A;  2J1O A;  4LZC A;  3EGT A;  3MZV A;  3WCM A;  5DJP F;  1WMW A;  3AQC B;  2E8V A;  4LFV F;  3DYG A;  3ZOU A;  3WCE A;  2E8T A;  2ZCQ A;  5CG5 A;  3WJK A;  2E92 A;  2ZY1 A;  4OMH A;  1WL3 A;  1HM4 A;  1YYR A;  4NFI F;  4PVY F;  4L2X F;  3VJA A;  1VG2 A;  3B7L A;  5E8L A;  5DGM F;  3PKO A;  2DH4 A;  3KB9 A;  4QPF A;  3N49 F;  2OPN A;  1KIZ A;  2PS6 A;  3LGK A;  4P0W A;  5IL8 A;  5IN8 A;  3N3L F;  4KWD A;  4KQ5 A;  3WEH A;  3TFV A;  1VG6 A;  2E90 A;  3N0F A;  4RYP A;  5DJR F;  4F62 A;  4FJQ A;  2PS5 A;  4KUX A;  4N1Z F;  4KKM A;  4RXC A;  3NPK A;  3AQ0 A;  1N24 A;  2Q80 A;  4E9Z A;  3EFQ A;  1N20 A;  3ZMB A;  4F6X A;  1YHK A;  1HM7 A;  5B0M A;  5ILZ A;  4HD1 A;  2AZJ A;  3NRI A;  3RYW A;  4LLS A;  4H5C F;  4LTZ A;  4LXW A;  1WY0 A;  4OMG A;  2Q58 A;  4RNQ A;  3WEI A;  2O1O A;  3WSB A;  3ICK A;  3M01 A;  4QXS F;  1YHM A;  2F9K F;  3LG5 A;  3N5H F;  1ZW5 A;  1YYQ A;  3OAB A;  3RYE A;  3N1W F;  1N23 A;  5DGN F;  4JXY A;  3S9V A;  5IKA A;  1DI1 A;  4NFK F;  3TFP A;  2Q9Y A;  1HXG A;  2Z4V A;  3LZ9 A;  4JYX A;  3WCG A;  1DGP A;  2PS7 A;  2FOR A;  1RQI A;  4KQS A;  3BNX A;  3PDE A;  2Z4W A;  5IVG A;  4GP2 A;  3KRP A;  3TS7 A;  1JFA A;  5JV2 F;  2RAH A;  4JVJ F;  5ILH A;  3KRO A;  3VJ8 A;  4E9U A;  3SDT A;  3OAC B;  3W7F A;  3TFN A;  2E95 A;  3WCD A;  5JV0 F;  5H9D A;  3M00 A;  4RXD A;  4DHD A;  3Q30 A;  3G4F A;  5B0K A;  4KFA A;  2E91 A;  5JV1 F;  4LFG A;  4LA5 A;  4DXJ A;  1YJ4 A;  1WL2 A;  4N9U A;  3CP6 A;  3LLW A;  2AET A;  2PS8 A;  2ONG A;  2Q9Z A;  3KRC B;  3LJI A;  5A0J A;  3M02 A;  1V4E A;  5ILI A;  3WEK A;  2E4O A;  1VG3 A;  3VJB A;  3WCJ A;  5B02 A;  2Z78 A;  4NKF A;  3ACW A;  5E8K A;  4RXE A;  5JA0 F;  2Z4Z A;  3AQB B;  5IK0 A;  5B01 A;  1UBV A;  2Z7H A;  1N1B A;  3N1V F;  3N5J F;  2Z52 A;  3KRO B;  5IK9 A;  4LFE A;  4E1E A;  4LTV A;  2Z7I A;  3KRF B;  3RMG A;  3WC9 A;  5ILY A;  1WL0 A;  3SDR A;  3ICM A;  3SAE A;  5DW7 A;  1V4J A;  5B0L A;  4KVD A;  3WCB A;  4KVW A;  2AEK A;  4NG6 A;  5ILJ A;  2OA6 A;  4NFJ F;  3ICZ A;  3KRA A;  4KPJ A;  1HX9 A;  4UMJ A;  3CC9 A;  3VJD A;  1PS1 A;  3PH7 A;  1HXC A;  3LDW A;  2ZCS A;  5HN7 A;  3VJ9 A;  3LGZ B;  4OKZ A;  3Q2Z A;  1UBX A;  4GP1 A;  2OPM A;  1WKZ A;  3N3D A;  3OYR A;  3ZCD A;  1RQJ A;  3P5R A;  1YV5 A;  4P0X A;  4EA2 A;  3NF2 A;  3WCC A;  4PVX F;  3WSA A;  3ZL6 A;  3EZ3 A;  3WJO A;  4EA1 A;  3MAV A;  3CKE A;  4KVI A;  2E94 A;  3ACX A;  4LLT A;  5ERM A;  2Z4X A;  3M9U A;  5IK6 A;  2Z50 A;  1N22 A;  3QQV A;  2PS4 A;  3ICN A;  3WEJ A;  5HN9 A;  3LOM A;  3V1V A;  4MC0 A;  2ZEV A;  2AZK A;  3DYH A;  3M0G A;  3V1X A;  3KRA B;  5EAS A;  3Q2Q A;  4KVY A;  1VG4 A;  4NKE A;  4KK2 A;  5IL3 A;  4GAX A;  4FP4 A;  5B00 A;  4JZX A;  2AZL A;  4OKM A;  4RXA A;  1N21 A;  2E8X A;  5IMP A;  4LOB A;  3IPI A;  3LK5 A;  4XQT F;  1KIY A;  1YYS A;  5B03 A;  3P8L A;  4KPD A;  3ACY A;  3SDU A;  3G4D A;  3N45 F;  3BNY A;  5EAT A;  4LA6 A;  4JXN A;  3WEF A;  5KSX F;  2AEL A;  3LMD A;  3OAB B;  5DZ2 A;  5ILD A;  4K10 A;  3VJE A;  5HN8 A;  2ZEU A;  4DZW A;  2ZCR A;  2Z4Y A;  2EWG A;  1HXA A;  2OGD A;  3NPR A;  4EA0 A;  5IM1 A;  4H5E F;  2F94 F;  5IMN A;  3N6K F;  1V4I A;  3KRP B;  3PYB A;  3P5P A;  3WE9 A;  2E93 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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