3WEFA

Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
334
structure length
327
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Squalene synthase
publication title Structural insights into the catalytic mechanism of human squalene synthase
doi rcsb
source organism Homo sapiens
total genus 134
structure length 327
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wefA00
3AQBB 2E92A 4NFJF 5HN8A 1WL1A 4KWDA 4WK5A 3Q1OA 3LDWA 4DXJA 3WC9A 4KKMA 5E8HA 4K10A 3DYGA 1VG2A 4GAXA 2ONGA 2ZCSA 3ACWA 4LUUA 1HXCA 5B0MA 3V66A 4LLTA 2AEKA 2RAHA 1V4IA 3LK5A 5B0LA 3ASXA 3WCGA 4LPGF 5B01A 4N1ZF 3NPRA 5HN7A 2ZCQA 5DGMF 3N0FA 2FTZA 4RXCA 3KBKA 3EZ3A 3P8LA 4KFAA 2J1PA 4P0WA 1UBYA 2PS7A 3PKOA 3N46F 4LZ0A 2AZJA 3AQCB 5ILJA 3N5JF 2ZEVA 4MC8A 5KSXF 3SDRA 5DIQF 4KPDA 3NRIA 4PVYF 3LLWA 5IKAA 3N6KF 5IVGA 4LXWA 3ACXA 3CC9A 3N1VF 3NPKA 3RBMA 2F89F 4DZWA 1HM7A 3BNYA 5HNAA 1DI1A 4KVIA 3WCLA 3VJ8A 2ZY1A 4LLSA 3S9VA 4LFEA 4JVJF 5I1UA 1RQIA 2F94F 1JFGA 4LFVF 2Q58A 2Z78A 3WJOA 4GA3A 5B0KA 3BNXA 3WE9A 4E9ZA 2Z4VA 4QPFA 3RYEA 3WCDA 3WEKA 2E8UA 2DH4A 2OPNA 3MAVA 3WJNA 4LA6A 1DGPA 5DW7A 5DHIA 3PYBA 1VG6A 3WCBA 3LVSA 4DEMF 1WL0A 3NF2A 4OKZA 3CKEA 4EA0A 3TFPA 5CG5A 3KRPA 2OGDA 3Q2QA 5JV0F 4KPJA 3G4FA 5ILKA 5EASA 1KIYA 4DWBA 3V1XA 1N20A 3N0GA 4RXDA 5DJPF 3ZL6A 3KB9A 2OPMA 3ACYA 3VJDA 5IK0A 3DYHA 2E94A 5EROA 4P0VA 4XQRF 3TFNA 5IMNA 2PS8A 3WJKA 1HX9A 4OGUA 3Q30A 5DJVF 4MC0A 5B0JA 3WCHA 5ERMA 3VJ9A 3SDTA 3LEEA 3B7LA 5CG6A 4GP2A 4MC3A 4ZQ8A 3QKCA 5B03A 2OA6A 5IMPA 4LIXA 4KVDA 5EATA 5ILZA 3VJEA 2E8VA 1VG4A 4H5CF 3UCAA 5A0KA 5DZ2A 5JV1F 4LPHF 1WMWA 4NG6A 3ADZA 4JZXA 2Z4ZA 5JV2F 2F8CF 1FPSA 3LSNA 3M01A 3OABB 1EZFA 3ICZA 2AZKA 2ZEUA 5HN9A 2ZCRA 3S4JA 3OABA 3SDQA 4DWGA 1N21A 5AELA 3VJCA 1VG7A 4LA5A 3AE0A 2AETA 1UBWA 2PS5A 1YQ7A 4JXNA 5ER8A 4LTVA 5H9DA 1HM4A 4KQUA 4JYXA 4NUAA 4KVWA 5DJRF 1KIZA 2H8OA 1HXAA 3WCCA 4KUXA 2E8TA 3V1VA 3WCJA 5IL8A 4OKMA 2PS6A 3M00A 1V4EA 2O1OA 2Z7HA 2Z4YA 4RXEA 5DGNF 3WEFA 3TFVA 4F6VA 1WL2A 2Z4XA 3G4DA 3LZ9A 3M0GA 3OYRA 5B00A 1UBVA 2F7MF 4RNQA 2VF6A 3CP6A 3OACB 3ICMA 5ILHA 2Z4WA 5IK6A 3P8RA 5B02A 1WY0A 3P41A 3OACA 4UMJA 3EFQA 3WEJA 3TC1A 2AELA 2Z7IA 3ZOUA 4KK2A 3ZMCA 4KQSA 2Z52A 5DHKA 3TS7A 5B0IA 4EA2A 3WCAA 3SAEA 4F62A 3SDUA 3Q2ZA 2QISA 4PVXF 5JA0F 5JUZF 3WSAA 3LJIA 5ERNA 4KQ5A 3KROB 3KRAB 1WL3A 2E91A 4NKEA 3KRCB 5IKHA 5E8LA 5ILYA 2FORA 3WCIA 1V4JA 2J5CA 1YYUA 4P0XA 3DYFA 2F8ZF 1YJ4A 3N1WF 5A0IA 5C05A 4JZBA 4LTZA 1HXGA 1YHMA 1N22A 3N45F 2E8WA 2F9KF 4DI5A 3N3LF 4N9UA 3WEIA 5IMIA 2E90A 1N23A 3IBAA 5AYPA 5A0JA 5DGSF 2ZCOA 3IPIA 4OMGA 3ZMBA 4FP4A 4LOBA 2P1CA 4E9UA 1N24A 4NFKF 3PH7A 4HD1A 4XQSF 3ZCDA 3VJBA 1UBXA 3EGTA 3M9UA 3LG5A 3ID0A 3ICNA 5IK9A 4QXSF 3APZA 2E4OA 5ILDA 3PYAA 2EWGA 2E8XA 3PDEA 3WCFA 1N1BA 1YYRA 3WEGA 4L2XF 4Q23A 5AFXA 4NKFA 1PS1A 3LGKA 1V4HA 3KRFB 1YYTA 4LZCA 3AQ0A 3WSBA 3KRFA 1JFAA 1YHLA 4NFIF 4DHDA 2ONHA 2AZLA 2J1OA 3RMGA 3RYWA 3M02A 3WEHA 2Z50A 1YV5A 1ZW5A 3N49F 2Q9ZA 3N3DA 4GP1A 4JXYA 2I19A 2PS4A 4H5DF 5E8KA 3N5HF 5IL3A 3LMDA 1RTRA 3ICKA 3WCEA 4XQTF 1V4KA 1WKZA 1RQJA 3LOMA 2E93A 3WCMA 4FJQA 4KVYA 3P5RA 2Q9YA 4RYPA 3KRPB 1YYQA 4LFGA 3W7FA 4F6XA 3LGZB 3SDVA 5IM1A 4EA1A 5EAUA 5AHUB 2Q80A 1YYSA 1N1ZA 3VJAA 4H5EF 4OMHA 3QQVA 3KROA 3KRAA 4RXAA 5ILIA 2E95A 5IN8A 3P5PA 3KRCA 1YHKA 2F92F 4LZ3A 4E1EA 1VG3A 3MZVA
chains in the Genus database with same CATH superfamily
3AQBB 2E92A 4NFJF 5HN8A 1WL1A 4KWDA 4WK5A 3Q1OA 3LDWA 4DXJA 3WC9A 4KKMA 5E8HA 4K10A 3DYGA 1VG2A 4GAXA 2ONGA 2ZCSA 3ACWA 4LUUA 1HXCA 5B0MA 3V66A 4LLTA 2AEKA 2RAHA 1V4IA 3LK5A 5B0LA 3ASXA 3WCGA 4LPGF 5B01A 4N1ZF 3NPRA 5HN7A 2ZCQA 5DGMF 3N0FA 2FTZA 4RXCA 3KBKA 3EZ3A 3P8LA 4KFAA 2J1PA 4P0WA 1UBYA 2PS7A 3PKOA 3N46F 4LZ0A 2AZJA 3AQCB 5ILJA 3N5JF 2ZEVA 4MC8A 5KSXF 3SDRA 5DIQF 4KPDA 3NRIA 4PVYF 3LLWA 5IKAA 3N6KF 5IVGA 4LXWA 3ACXA 3CC9A 3N1VF 3NPKA 3RBMA 2F89F 4DZWA 1HM7A 3BNYA 5HNAA 1DI1A 4KVIA 3WCLA 3VJ8A 2ZY1A 4LLSA 3S9VA 4LFEA 4JVJF 5I1UA 1RQIA 2F94F 1JFGA 4LFVF 2Q58A 2Z78A 3WJOA 4GA3A 5B0KA 3BNXA 3WE9A 4E9ZA 2Z4VA 4QPFA 3RYEA 3WCDA 3WEKA 2E8UA 2DH4A 2OPNA 3MAVA 3WJNA 4LA6A 1DGPA 5DW7A 5DHIA 3PYBA 1VG6A 3WCBA 3LVSA 4DEMF 1WL0A 3NF2A 4OKZA 3CKEA 4EA0A 3TFPA 5CG5A 3KRPA 2OGDA 3Q2QA 5JV0F 4KPJA 3G4FA 5ILKA 5EASA 1KIYA 4DWBA 3V1XA 1N20A 3N0GA 4RXDA 5DJPF 3ZL6A 3KB9A 2OPMA 3ACYA 3VJDA 5IK0A 3DYHA 2E94A 5EROA 4P0VA 4XQRF 3TFNA 5IMNA 2PS8A 3WJKA 1HX9A 4OGUA 3Q30A 5DJVF 4MC0A 5B0JA 3WCHA 5ERMA 3VJ9A 3SDTA 3LEEA 3B7LA 5CG6A 4GP2A 4MC3A 4ZQ8A 3QKCA 5B03A 2OA6A 5IMPA 4LIXA 4KVDA 5EATA 5ILZA 3VJEA 2E8VA 1VG4A 4H5CF 3UCAA 5A0KA 5DZ2A 5JV1F 4LPHF 1WMWA 4NG6A 3ADZA 4JZXA 2Z4ZA 5JV2F 2F8CF 1FPSA 3LSNA 3M01A 3OABB 1EZFA 3ICZA 2AZKA 2ZEUA 5HN9A 2ZCRA 3S4JA 3OABA 3SDQA 4DWGA 1N21A 5AELA 3VJCA 1VG7A 4LA5A 3AE0A 2AETA 1UBWA 2PS5A 1YQ7A 4JXNA 5ER8A 4LTVA 5H9DA 1HM4A 4KQUA 4JYXA 4NUAA 4KVWA 5DJRF 1KIZA 2H8OA 1HXAA 3WCCA 4KUXA 2E8TA 3V1VA 3WCJA 5IL8A 4OKMA 2PS6A 3M00A 1V4EA 2O1OA 2Z7HA 2Z4YA 4RXEA 5DGNF 3WEFA 3TFVA 4F6VA 1WL2A 2Z4XA 3G4DA 3LZ9A 3M0GA 3OYRA 5B00A 1UBVA 2F7MF 4RNQA 2VF6A 3CP6A 3OACB 3ICMA 5ILHA 2Z4WA 5IK6A 3P8RA 5B02A 1WY0A 3P41A 3OACA 4UMJA 3EFQA 3WEJA 3TC1A 2AELA 2Z7IA 3ZOUA 4KK2A 3ZMCA 4KQSA 2Z52A 5DHKA 3TS7A 5B0IA 4EA2A 3WCAA 3SAEA 4F62A 3SDUA 3Q2ZA 2QISA 4PVXF 5JA0F 5JUZF 3WSAA 3LJIA 5ERNA 4KQ5A 3KROB 3KRAB 1WL3A 2E91A 4NKEA 3KRCB 5IKHA 5E8LA 5ILYA 2FORA 3WCIA 1V4JA 2J5CA 1YYUA 4P0XA 3DYFA 2F8ZF 1YJ4A 3N1WF 5A0IA 5C05A 4JZBA 4LTZA 1HXGA 1YHMA 1N22A 3N45F 2E8WA 2F9KF 4DI5A 3N3LF 4N9UA 3WEIA 5IMIA 2E90A 1N23A 3IBAA 5AYPA 5A0JA 5DGSF 2ZCOA 3IPIA 4OMGA 3ZMBA 4FP4A 4LOBA 2P1CA 4E9UA 1N24A 4NFKF 3PH7A 4HD1A 4XQSF 3ZCDA 3VJBA 1UBXA 3EGTA 3M9UA 3LG5A 3ID0A 3ICNA 5IK9A 4QXSF 3APZA 2E4OA 5ILDA 3PYAA 2EWGA 2E8XA 3PDEA 3WCFA 1N1BA 1YYRA 3WEGA 4L2XF 4Q23A 5AFXA 4NKFA 1PS1A 3LGKA 1V4HA 3KRFB 1YYTA 4LZCA 3AQ0A 3WSBA 3KRFA 1JFAA 1YHLA 4NFIF 4DHDA 2ONHA 2AZLA 2J1OA 3RMGA 3RYWA 3M02A 3WEHA 2Z50A 1YV5A 1ZW5A 3N49F 2Q9ZA 3N3DA 4GP1A 4JXYA 2I19A 2PS4A 4H5DF 5E8KA 3N5HF 5IL3A 3LMDA 1RTRA 3ICKA 3WCEA 4XQTF 1V4KA 1WKZA 1RQJA 3LOMA 2E93A 3WCMA 4FJQA 4KVYA 3P5RA 2Q9YA 4RYPA 3KRPB 1YYQA 4LFGA 3W7FA 4F6XA 3LGZB 3SDVA 5IM1A 4EA1A 5EAUA 5AHUB 2Q80A 1YYSA 1N1ZA 3VJAA 4H5EF 4OMHA 3QQVA 3KROA 3KRAA 4RXAA 5ILIA 2E95A 5IN8A 3P5PA 3KRCA 1YHKA 2F92F 4LZ3A 4E1EA 1VG3A 3MZVA
chains in the Genus database with same CATH topology
3AQBB 2E92A 4NFJF 5HN8A 1WL1A 4KWDA 4WK5A 3Q1OA 3LDWA 4DXJA 3WC9A 4KKMA 5E8HA 4K10A 3DYGA 1VG2A 4GAXA 2ONGA 2ZCSA 3ACWA 4LUUA 1HXCA 5B0MA 3V66A 4LLTA 2AEKA 2RAHA 1V4IA 3LK5A 5B0LA 3ASXA 3WCGA 4LPGF 5B01A 4N1ZF 3NPRA 5HN7A 2ZCQA 5DGMF 3N0FA 2FTZA 4RXCA 3KBKA 3EZ3A 3P8LA 4KFAA 2J1PA 4P0WA 1UBYA 2PS7A 3PKOA 3N46F 4LZ0A 2AZJA 3AQCB 5ILJA 3N5JF 2ZEVA 4MC8A 5KSXF 3SDRA 5DIQF 4KPDA 3NRIA 4PVYF 3LLWA 5IKAA 3N6KF 5IVGA 4LXWA 3ACXA 3CC9A 3N1VF 3NPKA 3RBMA 2F89F 4DZWA 1HM7A 3BNYA 5HNAA 1DI1A 4KVIA 3WCLA 3VJ8A 2ZY1A 4LLSA 3S9VA 4LFEA 4JVJF 5I1UA 1RQIA 2F94F 1JFGA 4LFVF 2Q58A 2Z78A 3WJOA 4GA3A 5B0KA 3BNXA 3WE9A 4E9ZA 2Z4VA 4QPFA 3RYEA 3WCDA 3WEKA 2E8UA 2DH4A 2OPNA 3MAVA 3WJNA 4LA6A 1DGPA 5DW7A 5DHIA 3PYBA 1VG6A 3WCBA 3LVSA 4DEMF 1WL0A 3NF2A 4OKZA 3CKEA 4EA0A 3TFPA 5CG5A 3KRPA 2OGDA 3Q2QA 5JV0F 4KPJA 3G4FA 5ILKA 5EASA 1KIYA 4DWBA 3V1XA 1N20A 3N0GA 4RXDA 5DJPF 3ZL6A 3KB9A 2OPMA 3ACYA 3VJDA 5IK0A 3DYHA 2E94A 5EROA 4P0VA 4XQRF 3TFNA 5IMNA 2PS8A 3WJKA 1HX9A 4OGUA 3Q30A 5DJVF 4MC0A 5B0JA 3WCHA 5ERMA 3VJ9A 3SDTA 3LEEA 3B7LA 5CG6A 4GP2A 4MC3A 4ZQ8A 3QKCA 5B03A 2OA6A 5IMPA 4LIXA 4KVDA 5EATA 5ILZA 3VJEA 2E8VA 1VG4A 4H5CF 3UCAA 5A0KA 5DZ2A 5JV1F 4LPHF 1WMWA 4NG6A 3ADZA 4JZXA 2Z4ZA 5JV2F 2F8CF 1FPSA 3LSNA 3M01A 3OABB 1EZFA 3ICZA 2AZKA 2ZEUA 5HN9A 2ZCRA 3S4JA 3OABA 3SDQA 4DWGA 1N21A 5AELA 3VJCA 1VG7A 4LA5A 3AE0A 2AETA 1UBWA 2PS5A 1YQ7A 4JXNA 5ER8A 4LTVA 5H9DA 1HM4A 4KQUA 4JYXA 4NUAA 4KVWA 5DJRF 1KIZA 2H8OA 1HXAA 3WCCA 4KUXA 2E8TA 3V1VA 3WCJA 5IL8A 4OKMA 2PS6A 3M00A 1V4EA 2O1OA 2Z7HA 2Z4YA 4RXEA 5DGNF 3WEFA 3TFVA 4F6VA 1WL2A 2Z4XA 3G4DA 3LZ9A 3M0GA 3OYRA 5B00A 1UBVA 2F7MF 4RNQA 2VF6A 3CP6A 3OACB 3ICMA 5ILHA 2Z4WA 5IK6A 3P8RA 5B02A 1WY0A 3P41A 3OACA 4UMJA 3EFQA 3WEJA 3TC1A 2AELA 2Z7IA 3ZOUA 4KK2A 3ZMCA 4KQSA 2Z52A 5DHKA 3TS7A 5B0IA 4EA2A 3WCAA 3SAEA 4F62A 3SDUA 3Q2ZA 2QISA 4PVXF 5JA0F 5JUZF 3WSAA 3LJIA 5ERNA 4KQ5A 3KROB 3KRAB 1WL3A 2E91A 4NKEA 3KRCB 5IKHA 5E8LA 5ILYA 2FORA 3WCIA 1V4JA 2J5CA 1YYUA 4P0XA 3DYFA 2F8ZF 1YJ4A 3N1WF 5A0IA 5C05A 4JZBA 4LTZA 1HXGA 1YHMA 1N22A 3N45F 2E8WA 2F9KF 4DI5A 3N3LF 4N9UA 3WEIA 5IMIA 2E90A 1N23A 3IBAA 5AYPA 5A0JA 5DGSF 2ZCOA 3IPIA 4OMGA 3ZMBA 4FP4A 4LOBA 2P1CA 4E9UA 1N24A 4NFKF 3PH7A 4HD1A 4XQSF 3ZCDA 3VJBA 1UBXA 3EGTA 3M9UA 3LG5A 3ID0A 3ICNA 5IK9A 4QXSF 3APZA 2E4OA 5ILDA 3PYAA 2EWGA 2E8XA 3PDEA 3WCFA 1N1BA 1YYRA 3WEGA 4L2XF 4Q23A 5AFXA 4NKFA 1PS1A 3LGKA 1V4HA 3KRFB 1YYTA 4LZCA 3AQ0A 3WSBA 3KRFA 1JFAA 1YHLA 4NFIF 4DHDA 2ONHA 2AZLA 2J1OA 3RMGA 3RYWA 3M02A 3WEHA 2Z50A 1YV5A 1ZW5A 3N49F 2Q9ZA 3N3DA 4GP1A 4JXYA 2I19A 2PS4A 4H5DF 5E8KA 3N5HF 5IL3A 3LMDA 1RTRA 3ICKA 3WCEA 4XQTF 1V4KA 1WKZA 1RQJA 3LOMA 2E93A 3WCMA 4FJQA 4KVYA 3P5RA 2Q9YA 4RYPA 3KRPB 1YYQA 4LFGA 3W7FA 4F6XA 3LGZB 3SDVA 5IM1A 4EA1A 5EAUA 5AHUB 2Q80A 1YYSA 1N1ZA 3VJAA 4H5EF 4OMHA 3QQVA 3KROA 3KRAA 4RXAA 5ILIA 2E95A 5IN8A 3P5PA 3KRCA 1YHKA 2F92F 4LZ3A 4E1EA 1VG3A 3MZVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AQB B;  2E92 A;  4NFJ F;  5HN8 A;  1WL1 A;  4KWD A;  4WK5 A;  3Q1O A;  3LDW A;  4DXJ A;  3WC9 A;  4KKM A;  5E8H A;  4K10 A;  3DYG A;  1VG2 A;  4GAX A;  2ONG A;  2ZCS A;  3ACW A;  4LUU A;  1HXC A;  5B0M A;  3V66 A;  4LLT A;  2AEK A;  2RAH A;  1V4I A;  3LK5 A;  5B0L A;  3ASX A;  3WCG A;  4LPG F;  5B01 A;  4N1Z F;  3NPR A;  5HN7 A;  2ZCQ A;  5DGM F;  3N0F A;  2FTZ A;  4RXC A;  3KBK A;  3EZ3 A;  3P8L A;  4KFA A;  2J1P A;  4P0W A;  1UBY A;  2PS7 A;  3PKO A;  3N46 F;  4LZ0 A;  2AZJ A;  3AQC B;  5ILJ A;  3N5J F;  2ZEV A;  4MC8 A;  5KSX F;  3SDR A;  5DIQ F;  4KPD A;  3NRI A;  4PVY F;  3LLW A;  5IKA A;  3N6K F;  5IVG A;  4LXW A;  3ACX A;  3CC9 A;  3N1V F;  3NPK A;  3RBM A;  2F89 F;  4DZW A;  1HM7 A;  3BNY A;  5HNA A;  1DI1 A;  4KVI A;  3WCL A;  3VJ8 A;  2ZY1 A;  4LLS A;  3S9V A;  4LFE A;  4JVJ F;  5I1U A;  1RQI A;  2F94 F;  1JFG A;  4LFV F;  2Q58 A;  2Z78 A;  3WJO A;  4GA3 A;  5B0K A;  3BNX A;  3WE9 A;  4E9Z A;  2Z4V A;  4QPF A;  3RYE A;  3WCD A;  3WEK A;  2E8U A;  2DH4 A;  2OPN A;  3MAV A;  3WJN A;  4LA6 A;  1DGP A;  5DW7 A;  5DHI A;  3PYB A;  1VG6 A;  3WCB A;  3LVS A;  4DEM F;  1WL0 A;  3NF2 A;  4OKZ A;  3CKE A;  4EA0 A;  3TFP A;  5CG5 A;  3KRP A;  2OGD A;  3Q2Q A;  5JV0 F;  4KPJ A;  3G4F A;  5ILK A;  5EAS A;  1KIY A;  4DWB A;  3V1X A;  1N20 A;  3N0G A;  4RXD A;  5DJP F;  3ZL6 A;  3KB9 A;  2OPM A;  3ACY A;  3VJD A;  5IK0 A;  3DYH A;  2E94 A;  5ERO A;  4P0V A;  4XQR F;  3TFN A;  5IMN A;  2PS8 A;  3WJK A;  1HX9 A;  4OGU A;  3Q30 A;  5DJV F;  4MC0 A;  5B0J A;  3WCH A;  5ERM A;  3VJ9 A;  3SDT A;  3LEE A;  3B7L A;  5CG6 A;  4GP2 A;  4MC3 A;  4ZQ8 A;  3QKC A;  5B03 A;  2OA6 A;  5IMP A;  4LIX A;  4KVD A;  5EAT A;  5ILZ A;  3VJE A;  2E8V A;  1VG4 A;  4H5C F;  3UCA A;  5A0K A;  5DZ2 A;  5JV1 F;  4LPH F;  1WMW A;  4NG6 A;  3ADZ A;  4JZX A;  2Z4Z A;  5JV2 F;  2F8C F;  1FPS A;  3LSN A;  3M01 A;  3OAB B;  1EZF A;  3ICZ A;  2AZK A;  2ZEU A;  5HN9 A;  2ZCR A;  3S4J A;  3OAB A;  3SDQ A;  4DWG A;  1N21 A;  5AEL A;  3VJC A;  1VG7 A;  4LA5 A;  3AE0 A;  2AET A;  1UBW A;  2PS5 A;  1YQ7 A;  4JXN A;  5ER8 A;  4LTV A;  5H9D A;  1HM4 A;  4KQU A;  4JYX A;  4NUA A;  4KVW A;  5DJR F;  1KIZ A;  2H8O A;  1HXA A;  3WCC A;  4KUX A;  2E8T A;  3V1V A;  3WCJ A;  5IL8 A;  4OKM A;  2PS6 A;  3M00 A;  1V4E A;  2O1O A;  2Z7H A;  2Z4Y A;  4RXE A;  5DGN F;  3WEF A;  3TFV A;  4F6V A;  1WL2 A;  2Z4X A;  3G4D A;  3LZ9 A;  3M0G A;  3OYR A;  5B00 A;  1UBV A;  2F7M F;  4RNQ A;  2VF6 A;  3CP6 A;  3OAC B;  3ICM A;  5ILH A;  2Z4W A;  5IK6 A;  3P8R A;  5B02 A;  1WY0 A;  3P41 A;  3OAC A;  4UMJ A;  3EFQ A;  3WEJ A;  3TC1 A;  2AEL A;  2Z7I A;  3ZOU A;  4KK2 A;  3ZMC A;  4KQS A;  2Z52 A;  5DHK A;  3TS7 A;  5B0I A;  4EA2 A;  3WCA A;  3SAE A;  4F62 A;  3SDU A;  3Q2Z A;  2QIS A;  4PVX F;  5JA0 F;  5JUZ F;  3WSA A;  3LJI A;  5ERN A;  4KQ5 A;  3KRO B;  3KRA B;  1WL3 A;  2E91 A;  4NKE A;  3KRC B;  5IKH A;  5E8L A;  5ILY A;  2FOR A;  3WCI A;  1V4J A;  2J5C A;  1YYU A;  4P0X A;  3DYF A;  2F8Z F;  1YJ4 A;  3N1W F;  5A0I A;  5C05 A;  4JZB A;  4LTZ A;  1HXG A;  1YHM A;  1N22 A;  3N45 F;  2E8W A;  2F9K F;  4DI5 A;  3N3L F;  4N9U A;  3WEI A;  5IMI A;  2E90 A;  1N23 A;  3IBA A;  5AYP A;  5A0J A;  5DGS F;  2ZCO A;  3IPI A;  4OMG A;  3ZMB A;  4FP4 A;  4LOB A;  2P1C A;  4E9U A;  1N24 A;  4NFK F;  3PH7 A;  4HD1 A;  4XQS F;  3ZCD A;  3VJB A;  1UBX A;  3EGT A;  3M9U A;  3LG5 A;  3ID0 A;  3ICN A;  5IK9 A;  4QXS F;  3APZ A;  2E4O A;  5ILD A;  3PYA A;  2EWG A;  2E8X A;  3PDE A;  3WCF A;  1N1B A;  1YYR A;  3WEG A;  4L2X F;  4Q23 A;  5AFX A;  4NKF A;  1PS1 A;  3LGK A;  1V4H A;  3KRF B;  1YYT A;  4LZC A;  3AQ0 A;  3WSB A;  3KRF A;  1JFA A;  1YHL A;  4NFI F;  4DHD A;  2ONH A;  2AZL A;  2J1O A;  3RMG A;  3RYW A;  3M02 A;  3WEH A;  2Z50 A;  1YV5 A;  1ZW5 A;  3N49 F;  2Q9Z A;  3N3D A;  4GP1 A;  4JXY A;  2I19 A;  2PS4 A;  4H5D F;  5E8K A;  3N5H F;  5IL3 A;  3LMD A;  1RTR A;  3ICK A;  3WCE A;  4XQT F;  1V4K A;  1WKZ A;  1RQJ A;  3LOM A;  2E93 A;  3WCM A;  4FJQ A;  4KVY A;  3P5R A;  2Q9Y A;  4RYP A;  3KRP B;  1YYQ A;  4LFG A;  3W7F A;  4F6X A;  3LGZ B;  3SDV A;  5IM1 A;  4EA1 A;  5EAU A;  5AHU B;  2Q80 A;  1YYS A;  1N1Z A;  3VJA A;  4H5E F;  4OMH A;  3QQV A;  3KRO A;  3KRA A;  4RXA A;  5ILI A;  2E95 A;  5IN8 A;  3P5P A;  3KRC A;  1YHK A;  2F92 F;  4LZ3 A;  4E1E A;  1VG3 A;  3MZV A; 
#chains in the Genus database with same CATH topology
 3AQB B;  2E92 A;  4NFJ F;  5HN8 A;  1WL1 A;  4KWD A;  4WK5 A;  3Q1O A;  3LDW A;  4DXJ A;  3WC9 A;  4KKM A;  5E8H A;  4K10 A;  3DYG A;  1VG2 A;  4GAX A;  2ONG A;  2ZCS A;  3ACW A;  4LUU A;  1HXC A;  5B0M A;  3V66 A;  4LLT A;  2AEK A;  2RAH A;  1V4I A;  3LK5 A;  5B0L A;  3ASX A;  3WCG A;  4LPG F;  5B01 A;  4N1Z F;  3NPR A;  5HN7 A;  2ZCQ A;  5DGM F;  3N0F A;  2FTZ A;  4RXC A;  3KBK A;  3EZ3 A;  3P8L A;  4KFA A;  2J1P A;  4P0W A;  1UBY A;  2PS7 A;  3PKO A;  3N46 F;  4LZ0 A;  2AZJ A;  3AQC B;  5ILJ A;  3N5J F;  2ZEV A;  4MC8 A;  5KSX F;  3SDR A;  5DIQ F;  4KPD A;  3NRI A;  4PVY F;  3LLW A;  5IKA A;  3N6K F;  5IVG A;  4LXW A;  3ACX A;  3CC9 A;  3N1V F;  3NPK A;  3RBM A;  2F89 F;  4DZW A;  1HM7 A;  3BNY A;  5HNA A;  1DI1 A;  4KVI A;  3WCL A;  3VJ8 A;  2ZY1 A;  4LLS A;  3S9V A;  4LFE A;  4JVJ F;  5I1U A;  1RQI A;  2F94 F;  1JFG A;  4LFV F;  2Q58 A;  2Z78 A;  3WJO A;  4GA3 A;  5B0K A;  3BNX A;  3WE9 A;  4E9Z A;  2Z4V A;  4QPF A;  3RYE A;  3WCD A;  3WEK A;  2E8U A;  2DH4 A;  2OPN A;  3MAV A;  3WJN A;  4LA6 A;  1DGP A;  5DW7 A;  5DHI A;  3PYB A;  1VG6 A;  3WCB A;  3LVS A;  4DEM F;  1WL0 A;  3NF2 A;  4OKZ A;  3CKE A;  4EA0 A;  3TFP A;  5CG5 A;  3KRP A;  2OGD A;  3Q2Q A;  5JV0 F;  4KPJ A;  3G4F A;  5ILK A;  5EAS A;  1KIY A;  4DWB A;  3V1X A;  1N20 A;  3N0G A;  4RXD A;  5DJP F;  3ZL6 A;  3KB9 A;  2OPM A;  3ACY A;  3VJD A;  5IK0 A;  3DYH A;  2E94 A;  5ERO A;  4P0V A;  4XQR F;  3TFN A;  5IMN A;  2PS8 A;  3WJK A;  1HX9 A;  4OGU A;  3Q30 A;  5DJV F;  4MC0 A;  5B0J A;  3WCH A;  5ERM A;  3VJ9 A;  3SDT A;  3LEE A;  3B7L A;  5CG6 A;  4GP2 A;  4MC3 A;  4ZQ8 A;  3QKC A;  5B03 A;  2OA6 A;  5IMP A;  4LIX A;  4KVD A;  5EAT A;  5ILZ A;  3VJE A;  2E8V A;  1VG4 A;  4H5C F;  3UCA A;  5A0K A;  5DZ2 A;  5JV1 F;  4LPH F;  1WMW A;  4NG6 A;  3ADZ A;  4JZX A;  2Z4Z A;  5JV2 F;  2F8C F;  1FPS A;  3LSN A;  3M01 A;  3OAB B;  1EZF A;  3ICZ A;  2AZK A;  2ZEU A;  5HN9 A;  2ZCR A;  3S4J A;  3OAB A;  3SDQ A;  4DWG A;  1N21 A;  5AEL A;  3VJC A;  1VG7 A;  4LA5 A;  3AE0 A;  2AET A;  1UBW A;  2PS5 A;  1YQ7 A;  4JXN A;  5ER8 A;  4LTV A;  5H9D A;  1HM4 A;  4KQU A;  4JYX A;  4NUA A;  4KVW A;  5DJR F;  1KIZ A;  2H8O A;  1HXA A;  3WCC A;  4KUX A;  2E8T A;  3V1V A;  3WCJ A;  5IL8 A;  4OKM A;  2PS6 A;  3M00 A;  1V4E A;  2O1O A;  2Z7H A;  2Z4Y A;  4RXE A;  5DGN F;  3WEF A;  3TFV A;  4F6V A;  1WL2 A;  2Z4X A;  3G4D A;  3LZ9 A;  3M0G A;  3OYR A;  5B00 A;  1UBV A;  2F7M F;  4RNQ A;  2VF6 A;  3CP6 A;  3OAC B;  3ICM A;  5ILH A;  2Z4W A;  5IK6 A;  3P8R A;  5B02 A;  1WY0 A;  3P41 A;  3OAC A;  4UMJ A;  3EFQ A;  3WEJ A;  3TC1 A;  2AEL A;  2Z7I A;  3ZOU A;  4KK2 A;  3ZMC A;  4KQS A;  2Z52 A;  5DHK A;  3TS7 A;  5B0I A;  4EA2 A;  3WCA A;  3SAE A;  4F62 A;  3SDU A;  3Q2Z A;  2QIS A;  4PVX F;  5JA0 F;  5JUZ F;  3WSA A;  3LJI A;  5ERN A;  4KQ5 A;  3KRO B;  3KRA B;  1WL3 A;  2E91 A;  4NKE A;  3KRC B;  5IKH A;  5E8L A;  5ILY A;  2FOR A;  3WCI A;  1V4J A;  2J5C A;  1YYU A;  4P0X A;  3DYF A;  2F8Z F;  1YJ4 A;  3N1W F;  5A0I A;  5C05 A;  4JZB A;  4LTZ A;  1HXG A;  1YHM A;  1N22 A;  3N45 F;  2E8W A;  2F9K F;  4DI5 A;  3N3L F;  4N9U A;  3WEI A;  5IMI A;  2E90 A;  1N23 A;  3IBA A;  5AYP A;  5A0J A;  5DGS F;  2ZCO A;  3IPI A;  4OMG A;  3ZMB A;  4FP4 A;  4LOB A;  2P1C A;  4E9U A;  1N24 A;  4NFK F;  3PH7 A;  4HD1 A;  4XQS F;  3ZCD A;  3VJB A;  1UBX A;  3EGT A;  3M9U A;  3LG5 A;  3ID0 A;  3ICN A;  5IK9 A;  4QXS F;  3APZ A;  2E4O A;  5ILD A;  3PYA A;  2EWG A;  2E8X A;  3PDE A;  3WCF A;  1N1B A;  1YYR A;  3WEG A;  4L2X F;  4Q23 A;  5AFX A;  4NKF A;  1PS1 A;  3LGK A;  1V4H A;  3KRF B;  1YYT A;  4LZC A;  3AQ0 A;  3WSB A;  3KRF A;  1JFA A;  1YHL A;  4NFI F;  4DHD A;  2ONH A;  2AZL A;  2J1O A;  3RMG A;  3RYW A;  3M02 A;  3WEH A;  2Z50 A;  1YV5 A;  1ZW5 A;  3N49 F;  2Q9Z A;  3N3D A;  4GP1 A;  4JXY A;  2I19 A;  2PS4 A;  4H5D F;  5E8K A;  3N5H F;  5IL3 A;  3LMD A;  1RTR A;  3ICK A;  3WCE A;  4XQT F;  1V4K A;  1WKZ A;  1RQJ A;  3LOM A;  2E93 A;  3WCM A;  4FJQ A;  4KVY A;  3P5R A;  2Q9Y A;  4RYP A;  3KRP B;  1YYQ A;  4LFG A;  3W7F A;  4F6X A;  3LGZ B;  3SDV A;  5IM1 A;  4EA1 A;  5EAU A;  5AHU B;  2Q80 A;  1YYS A;  1N1Z A;  3VJA A;  4H5E F;  4OMH A;  3QQV A;  3KRO A;  3KRA A;  4RXA A;  5ILI A;  2E95 A;  5IN8 A;  3P5P A;  3KRC A;  1YHK A;  2F92 F;  4LZ3 A;  4E1E A;  1VG3 A;  3MZV A; 
#chains in the Genus database with same CATH homology
 3AQB B;  2E92 A;  4NFJ F;  5HN8 A;  1WL1 A;  4KWD A;  4WK5 A;  3Q1O A;  3LDW A;  4DXJ A;  3WC9 A;  4KKM A;  5E8H A;  4K10 A;  3DYG A;  1VG2 A;  4GAX A;  2ONG A;  2ZCS A;  3ACW A;  4LUU A;  1HXC A;  5B0M A;  3V66 A;  4LLT A;  2AEK A;  2RAH A;  1V4I A;  3LK5 A;  5B0L A;  3ASX A;  3WCG A;  4LPG F;  5B01 A;  4N1Z F;  3NPR A;  5HN7 A;  2ZCQ A;  5DGM F;  3N0F A;  2FTZ A;  4RXC A;  3KBK A;  3EZ3 A;  3P8L A;  4KFA A;  2J1P A;  4P0W A;  1UBY A;  2PS7 A;  3PKO A;  3N46 F;  4LZ0 A;  2AZJ A;  3AQC B;  5ILJ A;  3N5J F;  2ZEV A;  4MC8 A;  5KSX F;  3SDR A;  5DIQ F;  4KPD A;  3NRI A;  4PVY F;  3LLW A;  5IKA A;  3N6K F;  5IVG A;  4LXW A;  3ACX A;  3CC9 A;  3N1V F;  3NPK A;  3RBM A;  2F89 F;  4DZW A;  1HM7 A;  3BNY A;  5HNA A;  1DI1 A;  4KVI A;  3WCL A;  3VJ8 A;  2ZY1 A;  4LLS A;  3S9V A;  4LFE A;  4JVJ F;  5I1U A;  1RQI A;  2F94 F;  1JFG A;  4LFV F;  2Q58 A;  2Z78 A;  3WJO A;  4GA3 A;  5B0K A;  3BNX A;  3WE9 A;  4E9Z A;  2Z4V A;  4QPF A;  3RYE A;  3WCD A;  3WEK A;  2E8U A;  2DH4 A;  2OPN A;  3MAV A;  3WJN A;  4LA6 A;  1DGP A;  5DW7 A;  5DHI A;  3PYB A;  1VG6 A;  3WCB A;  3LVS A;  4DEM F;  1WL0 A;  3NF2 A;  4OKZ A;  3CKE A;  4EA0 A;  3TFP A;  5CG5 A;  3KRP A;  2OGD A;  3Q2Q A;  5JV0 F;  4KPJ A;  3G4F A;  5ILK A;  5EAS A;  1KIY A;  4DWB A;  3V1X A;  1N20 A;  3N0G A;  4RXD A;  5DJP F;  3ZL6 A;  3KB9 A;  2OPM A;  3ACY A;  3VJD A;  5IK0 A;  3DYH A;  2E94 A;  5ERO A;  4P0V A;  4XQR F;  3TFN A;  5IMN A;  2PS8 A;  3WJK A;  1HX9 A;  4OGU A;  3Q30 A;  5DJV F;  4MC0 A;  5B0J A;  3WCH A;  5ERM A;  3VJ9 A;  3SDT A;  3LEE A;  3B7L A;  5CG6 A;  4GP2 A;  4MC3 A;  4ZQ8 A;  3QKC A;  5B03 A;  2OA6 A;  5IMP A;  4LIX A;  4KVD A;  5EAT A;  5ILZ A;  3VJE A;  2E8V A;  1VG4 A;  4H5C F;  3UCA A;  5A0K A;  5DZ2 A;  5JV1 F;  4LPH F;  1WMW A;  4NG6 A;  3ADZ A;  4JZX A;  2Z4Z A;  5JV2 F;  2F8C F;  1FPS A;  3LSN A;  3M01 A;  3OAB B;  1EZF A;  3ICZ A;  2AZK A;  2ZEU A;  5HN9 A;  2ZCR A;  3S4J A;  3OAB A;  3SDQ A;  4DWG A;  1N21 A;  5AEL A;  3VJC A;  1VG7 A;  4LA5 A;  3AE0 A;  2AET A;  1UBW A;  2PS5 A;  1YQ7 A;  4JXN A;  5ER8 A;  4LTV A;  5H9D A;  1HM4 A;  4KQU A;  4JYX A;  4NUA A;  4KVW A;  5DJR F;  1KIZ A;  2H8O A;  1HXA A;  3WCC A;  4KUX A;  2E8T A;  3V1V A;  3WCJ A;  5IL8 A;  4OKM A;  2PS6 A;  3M00 A;  1V4E A;  2O1O A;  2Z7H A;  2Z4Y A;  4RXE A;  5DGN F;  3WEF A;  3TFV A;  4F6V A;  1WL2 A;  2Z4X A;  3G4D A;  3LZ9 A;  3M0G A;  3OYR A;  5B00 A;  1UBV A;  2F7M F;  4RNQ A;  2VF6 A;  3CP6 A;  3OAC B;  3ICM A;  5ILH A;  2Z4W A;  5IK6 A;  3P8R A;  5B02 A;  1WY0 A;  3P41 A;  3OAC A;  4UMJ A;  3EFQ A;  3WEJ A;  3TC1 A;  2AEL A;  2Z7I A;  3ZOU A;  4KK2 A;  3ZMC A;  4KQS A;  2Z52 A;  5DHK A;  3TS7 A;  5B0I A;  4EA2 A;  3WCA A;  3SAE A;  4F62 A;  3SDU A;  3Q2Z A;  2QIS A;  4PVX F;  5JA0 F;  5JUZ F;  3WSA A;  3LJI A;  5ERN A;  4KQ5 A;  3KRO B;  3KRA B;  1WL3 A;  2E91 A;  4NKE A;  3KRC B;  5IKH A;  5E8L A;  5ILY A;  2FOR A;  3WCI A;  1V4J A;  2J5C A;  1YYU A;  4P0X A;  3DYF A;  2F8Z F;  1YJ4 A;  3N1W F;  5A0I A;  5C05 A;  4JZB A;  4LTZ A;  1HXG A;  1YHM A;  1N22 A;  3N45 F;  2E8W A;  2F9K F;  4DI5 A;  3N3L F;  4N9U A;  3WEI A;  5IMI A;  2E90 A;  1N23 A;  3IBA A;  5AYP A;  5A0J A;  5DGS F;  2ZCO A;  3IPI A;  4OMG A;  3ZMB A;  4FP4 A;  4LOB A;  2P1C A;  4E9U A;  1N24 A;  4NFK F;  3PH7 A;  4HD1 A;  4XQS F;  3ZCD A;  3VJB A;  1UBX A;  3EGT A;  3M9U A;  3LG5 A;  3ID0 A;  3ICN A;  5IK9 A;  4QXS F;  3APZ A;  2E4O A;  5ILD A;  3PYA A;  2EWG A;  2E8X A;  3PDE A;  3WCF A;  1N1B A;  1YYR A;  3WEG A;  4L2X F;  4Q23 A;  5AFX A;  4NKF A;  1PS1 A;  3LGK A;  1V4H A;  3KRF B;  1YYT A;  4LZC A;  3AQ0 A;  3WSB A;  3KRF A;  1JFA A;  1YHL A;  4NFI F;  4DHD A;  2ONH A;  2AZL A;  2J1O A;  3RMG A;  3RYW A;  3M02 A;  3WEH A;  2Z50 A;  1YV5 A;  1ZW5 A;  3N49 F;  2Q9Z A;  3N3D A;  4GP1 A;  4JXY A;  2I19 A;  2PS4 A;  4H5D F;  5E8K A;  3N5H F;  5IL3 A;  3LMD A;  1RTR A;  3ICK A;  3WCE A;  4XQT F;  1V4K A;  1WKZ A;  1RQJ A;  3LOM A;  2E93 A;  3WCM A;  4FJQ A;  4KVY A;  3P5R A;  2Q9Y A;  4RYP A;  3KRP B;  1YYQ A;  4LFG A;  3W7F A;  4F6X A;  3LGZ B;  3SDV A;  5IM1 A;  4EA1 A;  5EAU A;  5AHU B;  2Q80 A;  1YYS A;  1N1Z A;  3VJA A;  4H5E F;  4OMH A;  3QQV A;  3KRO A;  3KRA A;  4RXA A;  5ILI A;  2E95 A;  5IN8 A;  3P5P A;  3KRC A;  1YHK A;  2F92 F;  4LZ3 A;  4E1E A;  1VG3 A;  3MZV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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