5DIQF

Crystal structure of human fpps in complex with salicylic acid derivative 3a
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
345
structure length
345
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 134
structure length 345
sequence length 345
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5diqF00
2FTZA 5IVGA 3UCAA 3Q30A 1DI1A 1YV5A 1RQIA 3Q1OA 1VG2A 3MZVA 5DIQF 3WCLA 2ZCSA 2ZEUA 3ACYA 4KPJA 3V66A 1YYTA 3S4JA 4RXEA 3OACA 3TC1A 4E1EA 3AQCB 4LPHF 1YYUA 1JFAA 1VG4A 4E9UA 4N9UA 4E9ZA 1N21A 5AYPA 2J1OA 4NG6A 5DHIA 3LG5A 3VJ9A 2VF6A 2Z4ZA 4RYPA 2AZKA 5EAUA 5HN7A 2AEKA 2E91A 4QPFA 2F8ZF 5HN8A 3OACB 4N1ZF 4LFVF 4MC0A 3WEFA 1WKZA 2Q58A 3KROA 3N45F 4KVYA 1YYSA 1V4IA 4MC8A 5IMNA 3N3LF 3PH7A 5IMIA 5A0IA 4P0VA 4HD1A 2Z4XA 5KSXF 3PYAA 2Q9YA 4NFJF 2OGDA 3B7LA 1YYRA 3PDEA 3KROB 3VJ8A 5IN8A 3WJOA 3WJKA 1YQ7A 3N46F 3RBMA 3CC9A 4F62A 3LOMA 1N22A 4DEMF 2Z7HA 2F89F 3SDQA 3P5PA 4OGUA 3DYHA 3P8RA 3DYGA 4KQSA 2AETA 5IL8A 3PKOA 4NKFA 4H5EF 4EA1A 3WCAA 4LLSA 4LZCA 4PVXF 1EZFA 5JUZF 5IK0A 2PS4A 1UBYA 1N24A 4XQSF 4JVJF 4RXAA 2ZY1A 4LFEA 3G4FA 2Q9ZA 2E92A 3M01A 4PVYF 2F92F 3LGZB 3CKEA 5B01A 3N0GA 1YHKA 5DJRF 3RYWA 3G4DA 2ZCQA 4NUAA 1HXCA 3N3DA 4DXJA 3CP6A 4GP1A 4RNQA 2E4OA 3VJAA 2PS6A 2PS5A 3LK5A 5IKAA 1JFGA 3IBAA 5B0JA 3LSNA 2OPNA 1YJ4A 4GA3A 1WMWA 2Z4VA 3KRPA 3AE0A 3S9VA 4EA2A 5IM1A 3TFNA 3IPIA 4JXNA 4DWBA 4FP4A 3Q2ZA 2J5CA 5A0KA 3WE9A 4QXSF 2Z4YA 4L2XF 1RTRA 3KRPB 2E93A 5DHKA 2AZJA 4FJQA 4GAXA 4NKEA 3TFVA 3Q2QA 2ZCRA 2O1OA 3EFQA 3LMDA 1HXGA 3RMGA 3VJCA 4F6XA 3N0FA 3LJIA 5ER8A 4DWGA 5HN9A 1HM4A 4XQTF 4XQRF 4Q23A 3WCFA 3KRCA 4LTVA 3WCMA 4LFGA 2E90A 3ID0A 4KQ5A 1V4JA 3OABA 4UMJA 5AELA 4JZXA 4KK2A 5DJVF 5B03A 1N23A 4LA6A 3KRCB 4LIXA 4LPGF 2Z7IA 4P0WA 3VJEA 1UBXA 3WSAA 3SAEA 3ACWA 2ZCOA 2E8XA 3BNYA 5AFXA 4P0XA 3ICZA 3OABB 1YHLA 1V4HA 2F7MF 3WSBA 4LXWA 4KVDA 4F6VA 5IMPA 3WC9A 3NRIA 4ZQ8A 4KKMA 4KFAA 5B0MA 5ERNA 1PS1A 5JV0F 5A0JA 1VG3A 5C05A 1N20A 3MAVA 3ZCDA 3WCIA 5E8KA 3ZMCA 3M0GA 4JXYA 3N6KF 3RYEA 1WL2A 3ICNA 4DI5A 2P1CA 3SDUA 3ASXA 1WL1A 5ILZA 3SDVA 2PS7A 2ONHA 1WL3A 2RAHA 3WEGA 4LZ0A 5DW7A 3EZ3A 3M00A 3WJNA 2F94F 3P5RA 1KIZA 2E94A 5AHUB 3M02A 1YYQA 2Z78A 5JA0F 3WEHA 3N5JF 2Q80A 1KIYA 3NPKA 1N1BA 3ZOUA 3NPRA 5EROA 1DGPA 5DZ2A 3BNXA 3AQ0A 5IKHA 5B02A 5B00A 4JYXA 3V1XA 1VG7A 5HNAA 4NFKF 5ILHA 4DZWA 5JV1F 3WCBA 3N49F 4GP2A 2E8UA 4JZBA 4H5CF 4K10A 4OKZA 1RQJA 4KQUA 1ZW5A 3N1VF 2ONGA 4OMGA 2Z50A 3ICMA 3V1VA 3TFPA 3LZ9A 4LA5A 4OKMA 3P41A 4EA0A 3TS7A 3KRAA 4WK5A 4LZ3A 3WEIA 3LEEA 5ERMA 3WCJA 4H5DF 2EWGA 2E8WA 1WY0A 5ILYA 5B0IA 1WL0A 3SDRA 2QISA 5ILJA 3KRAB 2E8TA 3ICKA 3NF2A 1N1ZA 4KVIA 5B0KA 5ILKA 5DGSF 3EGTA 4LTZA 2OPMA 2F9KF 2AELA 3QKCA 3VJDA 3ADZA 5ILIA 3WCEA 3WCCA 2DH4A 4DHDA 3LDWA 5DJPF 3LVSA 3VJBA 4LOBA 5EATA 3APZA 4KUXA 3WEJA 5IK6A 4KVWA 3WEKA 2H8OA 5E8HA 5CG6A 2E8VA 1V4EA 3KBKA 2PS8A 3OYRA 1YHMA 4OMHA 4RXCA 3ZMBA 1UBVA 5DGMF 4MC3A 5IK9A 4KWDA 4LLTA 3AQBB 3KB9A 3P8LA 5EASA 3ZL6A 1HX9A 5B0LA 1VG6A 4KPDA 1V4KA 5CG5A 1FPSA 4LUUA 5H9DA 3ACXA 4NFIF 5DGNF 2E95A 5I1UA 3LLWA 2Z4WA 1UBWA 2J1PA 3KRFA 5E8LA 3PYBA 3LGKA 4RXDA 2FORA 3WCHA 2I19A 2F8CF 3DYFA 3M9UA 2Z52A 3N5HF 3N1WF 1HM7A 1HXAA 2AZLA 3WCDA 3QQVA 2OA6A 3WCGA 5ILDA 3KRFB 5JV2F 3W7FA 5IL3A 3SDTA 2ZEVA
chains in the Genus database with same CATH superfamily
2FTZA 5IVGA 3UCAA 3Q30A 1DI1A 1YV5A 1RQIA 3Q1OA 1VG2A 3MZVA 5DIQF 3WCLA 2ZCSA 2ZEUA 3ACYA 4KPJA 3V66A 1YYTA 3S4JA 4RXEA 3OACA 3TC1A 4E1EA 3AQCB 4LPHF 1YYUA 1JFAA 1VG4A 4E9UA 4N9UA 4E9ZA 1N21A 5AYPA 2J1OA 4NG6A 5DHIA 3LG5A 3VJ9A 2VF6A 2Z4ZA 4RYPA 2AZKA 5EAUA 5HN7A 2AEKA 2E91A 4QPFA 2F8ZF 5HN8A 3OACB 4N1ZF 4LFVF 4MC0A 3WEFA 1WKZA 2Q58A 3KROA 3N45F 4KVYA 1YYSA 1V4IA 4MC8A 5IMNA 3N3LF 3PH7A 5IMIA 5A0IA 4P0VA 4HD1A 2Z4XA 5KSXF 3PYAA 2Q9YA 4NFJF 2OGDA 3B7LA 1YYRA 3PDEA 3KROB 3VJ8A 5IN8A 3WJOA 3WJKA 1YQ7A 3N46F 3RBMA 3CC9A 4F62A 3LOMA 1N22A 4DEMF 2Z7HA 2F89F 3SDQA 3P5PA 4OGUA 3DYHA 3P8RA 3DYGA 4KQSA 2AETA 5IL8A 3PKOA 4NKFA 4H5EF 4EA1A 3WCAA 4LLSA 4LZCA 4PVXF 1EZFA 5JUZF 5IK0A 2PS4A 1UBYA 1N24A 4XQSF 4JVJF 4RXAA 2ZY1A 4LFEA 3G4FA 2Q9ZA 2E92A 3M01A 4PVYF 2F92F 3LGZB 3CKEA 5B01A 3N0GA 1YHKA 5DJRF 3RYWA 3G4DA 2ZCQA 4NUAA 1HXCA 3N3DA 4DXJA 3CP6A 4GP1A 4RNQA 2E4OA 3VJAA 2PS6A 2PS5A 3LK5A 5IKAA 1JFGA 3IBAA 5B0JA 3LSNA 2OPNA 1YJ4A 4GA3A 1WMWA 2Z4VA 3KRPA 3AE0A 3S9VA 4EA2A 5IM1A 3TFNA 3IPIA 4JXNA 4DWBA 4FP4A 3Q2ZA 2J5CA 5A0KA 3WE9A 4QXSF 2Z4YA 4L2XF 1RTRA 3KRPB 2E93A 5DHKA 2AZJA 4FJQA 4GAXA 4NKEA 3TFVA 3Q2QA 2ZCRA 2O1OA 3EFQA 3LMDA 1HXGA 3RMGA 3VJCA 4F6XA 3N0FA 3LJIA 5ER8A 4DWGA 5HN9A 1HM4A 4XQTF 4XQRF 4Q23A 3WCFA 3KRCA 4LTVA 3WCMA 4LFGA 2E90A 3ID0A 4KQ5A 1V4JA 3OABA 4UMJA 5AELA 4JZXA 4KK2A 5DJVF 5B03A 1N23A 4LA6A 3KRCB 4LIXA 4LPGF 2Z7IA 4P0WA 3VJEA 1UBXA 3WSAA 3SAEA 3ACWA 2ZCOA 2E8XA 3BNYA 5AFXA 4P0XA 3ICZA 3OABB 1YHLA 1V4HA 2F7MF 3WSBA 4LXWA 4KVDA 4F6VA 5IMPA 3WC9A 3NRIA 4ZQ8A 4KKMA 4KFAA 5B0MA 5ERNA 1PS1A 5JV0F 5A0JA 1VG3A 5C05A 1N20A 3MAVA 3ZCDA 3WCIA 5E8KA 3ZMCA 3M0GA 4JXYA 3N6KF 3RYEA 1WL2A 3ICNA 4DI5A 2P1CA 3SDUA 3ASXA 1WL1A 5ILZA 3SDVA 2PS7A 2ONHA 1WL3A 2RAHA 3WEGA 4LZ0A 5DW7A 3EZ3A 3M00A 3WJNA 2F94F 3P5RA 1KIZA 2E94A 5AHUB 3M02A 1YYQA 2Z78A 5JA0F 3WEHA 3N5JF 2Q80A 1KIYA 3NPKA 1N1BA 3ZOUA 3NPRA 5EROA 1DGPA 5DZ2A 3BNXA 3AQ0A 5IKHA 5B02A 5B00A 4JYXA 3V1XA 1VG7A 5HNAA 4NFKF 5ILHA 4DZWA 5JV1F 3WCBA 3N49F 4GP2A 2E8UA 4JZBA 4H5CF 4K10A 4OKZA 1RQJA 4KQUA 1ZW5A 3N1VF 2ONGA 4OMGA 2Z50A 3ICMA 3V1VA 3TFPA 3LZ9A 4LA5A 4OKMA 3P41A 4EA0A 3TS7A 3KRAA 4WK5A 4LZ3A 3WEIA 3LEEA 5ERMA 3WCJA 4H5DF 2EWGA 2E8WA 1WY0A 5ILYA 5B0IA 1WL0A 3SDRA 2QISA 5ILJA 3KRAB 2E8TA 3ICKA 3NF2A 1N1ZA 4KVIA 5B0KA 5ILKA 5DGSF 3EGTA 4LTZA 2OPMA 2F9KF 2AELA 3QKCA 3VJDA 3ADZA 5ILIA 3WCEA 3WCCA 2DH4A 4DHDA 3LDWA 5DJPF 3LVSA 3VJBA 4LOBA 5EATA 3APZA 4KUXA 3WEJA 5IK6A 4KVWA 3WEKA 2H8OA 5E8HA 5CG6A 2E8VA 1V4EA 3KBKA 2PS8A 3OYRA 1YHMA 4OMHA 4RXCA 3ZMBA 1UBVA 5DGMF 4MC3A 5IK9A 4KWDA 4LLTA 3AQBB 3KB9A 3P8LA 5EASA 3ZL6A 1HX9A 5B0LA 1VG6A 4KPDA 1V4KA 5CG5A 1FPSA 4LUUA 5H9DA 3ACXA 4NFIF 5DGNF 2E95A 5I1UA 3LLWA 2Z4WA 1UBWA 2J1PA 3KRFA 5E8LA 3PYBA 3LGKA 4RXDA 2FORA 3WCHA 2I19A 2F8CF 3DYFA 3M9UA 2Z52A 3N5HF 3N1WF 1HM7A 1HXAA 2AZLA 3WCDA 3QQVA 2OA6A 3WCGA 5ILDA 3KRFB 5JV2F 3W7FA 5IL3A 3SDTA 2ZEVA
chains in the Genus database with same CATH topology
2FTZA 5IVGA 3UCAA 3Q30A 1DI1A 1YV5A 1RQIA 3Q1OA 1VG2A 3MZVA 5DIQF 3WCLA 2ZCSA 2ZEUA 3ACYA 4KPJA 3V66A 1YYTA 3S4JA 4RXEA 3OACA 3TC1A 4E1EA 3AQCB 4LPHF 1YYUA 1JFAA 1VG4A 4E9UA 4N9UA 4E9ZA 1N21A 5AYPA 2J1OA 4NG6A 5DHIA 3LG5A 3VJ9A 2VF6A 2Z4ZA 4RYPA 2AZKA 5EAUA 5HN7A 2AEKA 2E91A 4QPFA 2F8ZF 5HN8A 3OACB 4N1ZF 4LFVF 4MC0A 3WEFA 1WKZA 2Q58A 3KROA 3N45F 4KVYA 1YYSA 1V4IA 4MC8A 5IMNA 3N3LF 3PH7A 5IMIA 5A0IA 4P0VA 4HD1A 2Z4XA 5KSXF 3PYAA 2Q9YA 4NFJF 2OGDA 3B7LA 1YYRA 3PDEA 3KROB 3VJ8A 5IN8A 3WJOA 3WJKA 1YQ7A 3N46F 3RBMA 3CC9A 4F62A 3LOMA 1N22A 4DEMF 2Z7HA 2F89F 3SDQA 3P5PA 4OGUA 3DYHA 3P8RA 3DYGA 4KQSA 2AETA 5IL8A 3PKOA 4NKFA 4H5EF 4EA1A 3WCAA 4LLSA 4LZCA 4PVXF 1EZFA 5JUZF 5IK0A 2PS4A 1UBYA 1N24A 4XQSF 4JVJF 4RXAA 2ZY1A 4LFEA 3G4FA 2Q9ZA 2E92A 3M01A 4PVYF 2F92F 3LGZB 3CKEA 5B01A 3N0GA 1YHKA 5DJRF 3RYWA 3G4DA 2ZCQA 4NUAA 1HXCA 3N3DA 4DXJA 3CP6A 4GP1A 4RNQA 2E4OA 3VJAA 2PS6A 2PS5A 3LK5A 5IKAA 1JFGA 3IBAA 5B0JA 3LSNA 2OPNA 1YJ4A 4GA3A 1WMWA 2Z4VA 3KRPA 3AE0A 3S9VA 4EA2A 5IM1A 3TFNA 3IPIA 4JXNA 4DWBA 4FP4A 3Q2ZA 2J5CA 5A0KA 3WE9A 4QXSF 2Z4YA 4L2XF 1RTRA 3KRPB 2E93A 5DHKA 2AZJA 4FJQA 4GAXA 4NKEA 3TFVA 3Q2QA 2ZCRA 2O1OA 3EFQA 3LMDA 1HXGA 3RMGA 3VJCA 4F6XA 3N0FA 3LJIA 5ER8A 4DWGA 5HN9A 1HM4A 4XQTF 4XQRF 4Q23A 3WCFA 3KRCA 4LTVA 3WCMA 4LFGA 2E90A 3ID0A 4KQ5A 1V4JA 3OABA 4UMJA 5AELA 4JZXA 4KK2A 5DJVF 5B03A 1N23A 4LA6A 3KRCB 4LIXA 4LPGF 2Z7IA 4P0WA 3VJEA 1UBXA 3WSAA 3SAEA 3ACWA 2ZCOA 2E8XA 3BNYA 5AFXA 4P0XA 3ICZA 3OABB 1YHLA 1V4HA 2F7MF 3WSBA 4LXWA 4KVDA 4F6VA 5IMPA 3WC9A 3NRIA 4ZQ8A 4KKMA 4KFAA 5B0MA 5ERNA 1PS1A 5JV0F 5A0JA 1VG3A 5C05A 1N20A 3MAVA 3ZCDA 3WCIA 5E8KA 3ZMCA 3M0GA 4JXYA 3N6KF 3RYEA 1WL2A 3ICNA 4DI5A 2P1CA 3SDUA 3ASXA 1WL1A 5ILZA 3SDVA 2PS7A 2ONHA 1WL3A 2RAHA 3WEGA 4LZ0A 5DW7A 3EZ3A 3M00A 3WJNA 2F94F 3P5RA 1KIZA 2E94A 5AHUB 3M02A 1YYQA 2Z78A 5JA0F 3WEHA 3N5JF 2Q80A 1KIYA 3NPKA 1N1BA 3ZOUA 3NPRA 5EROA 1DGPA 5DZ2A 3BNXA 3AQ0A 5IKHA 5B02A 5B00A 4JYXA 3V1XA 1VG7A 5HNAA 4NFKF 5ILHA 4DZWA 5JV1F 3WCBA 3N49F 4GP2A 2E8UA 4JZBA 4H5CF 4K10A 4OKZA 1RQJA 4KQUA 1ZW5A 3N1VF 2ONGA 4OMGA 2Z50A 3ICMA 3V1VA 3TFPA 3LZ9A 4LA5A 4OKMA 3P41A 4EA0A 3TS7A 3KRAA 4WK5A 4LZ3A 3WEIA 3LEEA 5ERMA 3WCJA 4H5DF 2EWGA 2E8WA 1WY0A 5ILYA 5B0IA 1WL0A 3SDRA 2QISA 5ILJA 3KRAB 2E8TA 3ICKA 3NF2A 1N1ZA 4KVIA 5B0KA 5ILKA 5DGSF 3EGTA 4LTZA 2OPMA 2F9KF 2AELA 3QKCA 3VJDA 3ADZA 5ILIA 3WCEA 3WCCA 2DH4A 4DHDA 3LDWA 5DJPF 3LVSA 3VJBA 4LOBA 5EATA 3APZA 4KUXA 3WEJA 5IK6A 4KVWA 3WEKA 2H8OA 5E8HA 5CG6A 2E8VA 1V4EA 3KBKA 2PS8A 3OYRA 1YHMA 4OMHA 4RXCA 3ZMBA 1UBVA 5DGMF 4MC3A 5IK9A 4KWDA 4LLTA 3AQBB 3KB9A 3P8LA 5EASA 3ZL6A 1HX9A 5B0LA 1VG6A 4KPDA 1V4KA 5CG5A 1FPSA 4LUUA 5H9DA 3ACXA 4NFIF 5DGNF 2E95A 5I1UA 3LLWA 2Z4WA 1UBWA 2J1PA 3KRFA 5E8LA 3PYBA 3LGKA 4RXDA 2FORA 3WCHA 2I19A 2F8CF 3DYFA 3M9UA 2Z52A 3N5HF 3N1WF 1HM7A 1HXAA 2AZLA 3WCDA 3QQVA 2OA6A 3WCGA 5ILDA 3KRFB 5JV2F 3W7FA 5IL3A 3SDTA 2ZEVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FTZ A;  5IVG A;  3UCA A;  3Q30 A;  1DI1 A;  1YV5 A;  1RQI A;  3Q1O A;  1VG2 A;  3MZV A;  5DIQ F;  3WCL A;  2ZCS A;  2ZEU A;  3ACY A;  4KPJ A;  3V66 A;  1YYT A;  3S4J A;  4RXE A;  3OAC A;  3TC1 A;  4E1E A;  3AQC B;  4LPH F;  1YYU A;  1JFA A;  1VG4 A;  4E9U A;  4N9U A;  4E9Z A;  1N21 A;  5AYP A;  2J1O A;  4NG6 A;  5DHI A;  3LG5 A;  3VJ9 A;  2VF6 A;  2Z4Z A;  4RYP A;  2AZK A;  5EAU A;  5HN7 A;  2AEK A;  2E91 A;  4QPF A;  2F8Z F;  5HN8 A;  3OAC B;  4N1Z F;  4LFV F;  4MC0 A;  3WEF A;  1WKZ A;  2Q58 A;  3KRO A;  3N45 F;  4KVY A;  1YYS A;  1V4I A;  4MC8 A;  5IMN A;  3N3L F;  3PH7 A;  5IMI A;  5A0I A;  4P0V A;  4HD1 A;  2Z4X A;  5KSX F;  3PYA A;  2Q9Y A;  4NFJ F;  2OGD A;  3B7L A;  1YYR A;  3PDE A;  3KRO B;  3VJ8 A;  5IN8 A;  3WJO A;  3WJK A;  1YQ7 A;  3N46 F;  3RBM A;  3CC9 A;  4F62 A;  3LOM A;  1N22 A;  4DEM F;  2Z7H A;  2F89 F;  3SDQ A;  3P5P A;  4OGU A;  3DYH A;  3P8R A;  3DYG A;  4KQS A;  2AET A;  5IL8 A;  3PKO A;  4NKF A;  4H5E F;  4EA1 A;  3WCA A;  4LLS A;  4LZC A;  4PVX F;  1EZF A;  5JUZ F;  5IK0 A;  2PS4 A;  1UBY A;  1N24 A;  4XQS F;  4JVJ F;  4RXA A;  2ZY1 A;  4LFE A;  3G4F A;  2Q9Z A;  2E92 A;  3M01 A;  4PVY F;  2F92 F;  3LGZ B;  3CKE A;  5B01 A;  3N0G A;  1YHK A;  5DJR F;  3RYW A;  3G4D A;  2ZCQ A;  4NUA A;  1HXC A;  3N3D A;  4DXJ A;  3CP6 A;  4GP1 A;  4RNQ A;  2E4O A;  3VJA A;  2PS6 A;  2PS5 A;  3LK5 A;  5IKA A;  1JFG A;  3IBA A;  5B0J A;  3LSN A;  2OPN A;  1YJ4 A;  4GA3 A;  1WMW A;  2Z4V A;  3KRP A;  3AE0 A;  3S9V A;  4EA2 A;  5IM1 A;  3TFN A;  3IPI A;  4JXN A;  4DWB A;  4FP4 A;  3Q2Z A;  2J5C A;  5A0K A;  3WE9 A;  4QXS F;  2Z4Y A;  4L2X F;  1RTR A;  3KRP B;  2E93 A;  5DHK A;  2AZJ A;  4FJQ A;  4GAX A;  4NKE A;  3TFV A;  3Q2Q A;  2ZCR A;  2O1O A;  3EFQ A;  3LMD A;  1HXG A;  3RMG A;  3VJC A;  4F6X A;  3N0F A;  3LJI A;  5ER8 A;  4DWG A;  5HN9 A;  1HM4 A;  4XQT F;  4XQR F;  4Q23 A;  3WCF A;  3KRC A;  4LTV A;  3WCM A;  4LFG A;  2E90 A;  3ID0 A;  4KQ5 A;  1V4J A;  3OAB A;  4UMJ A;  5AEL A;  4JZX A;  4KK2 A;  5DJV F;  5B03 A;  1N23 A;  4LA6 A;  3KRC B;  4LIX A;  4LPG F;  2Z7I A;  4P0W A;  3VJE A;  1UBX A;  3WSA A;  3SAE A;  3ACW A;  2ZCO A;  2E8X A;  3BNY A;  5AFX A;  4P0X A;  3ICZ A;  3OAB B;  1YHL A;  1V4H A;  2F7M F;  3WSB A;  4LXW A;  4KVD A;  4F6V A;  5IMP A;  3WC9 A;  3NRI A;  4ZQ8 A;  4KKM A;  4KFA A;  5B0M A;  5ERN A;  1PS1 A;  5JV0 F;  5A0J A;  1VG3 A;  5C05 A;  1N20 A;  3MAV A;  3ZCD A;  3WCI A;  5E8K A;  3ZMC A;  3M0G A;  4JXY A;  3N6K F;  3RYE A;  1WL2 A;  3ICN A;  4DI5 A;  2P1C A;  3SDU A;  3ASX A;  1WL1 A;  5ILZ A;  3SDV A;  2PS7 A;  2ONH A;  1WL3 A;  2RAH A;  3WEG A;  4LZ0 A;  5DW7 A;  3EZ3 A;  3M00 A;  3WJN A;  2F94 F;  3P5R A;  1KIZ A;  2E94 A;  5AHU B;  3M02 A;  1YYQ A;  2Z78 A;  5JA0 F;  3WEH A;  3N5J F;  2Q80 A;  1KIY A;  3NPK A;  1N1B A;  3ZOU A;  3NPR A;  5ERO A;  1DGP A;  5DZ2 A;  3BNX A;  3AQ0 A;  5IKH A;  5B02 A;  5B00 A;  4JYX A;  3V1X A;  1VG7 A;  5HNA A;  4NFK F;  5ILH A;  4DZW A;  5JV1 F;  3WCB A;  3N49 F;  4GP2 A;  2E8U A;  4JZB A;  4H5C F;  4K10 A;  4OKZ A;  1RQJ A;  4KQU A;  1ZW5 A;  3N1V F;  2ONG A;  4OMG A;  2Z50 A;  3ICM A;  3V1V A;  3TFP A;  3LZ9 A;  4LA5 A;  4OKM A;  3P41 A;  4EA0 A;  3TS7 A;  3KRA A;  4WK5 A;  4LZ3 A;  3WEI A;  3LEE A;  5ERM A;  3WCJ A;  4H5D F;  2EWG A;  2E8W A;  1WY0 A;  5ILY A;  5B0I A;  1WL0 A;  3SDR A;  2QIS A;  5ILJ A;  3KRA B;  2E8T A;  3ICK A;  3NF2 A;  1N1Z A;  4KVI A;  5B0K A;  5ILK A;  5DGS F;  3EGT A;  4LTZ A;  2OPM A;  2F9K F;  2AEL A;  3QKC A;  3VJD A;  3ADZ A;  5ILI A;  3WCE A;  3WCC A;  2DH4 A;  4DHD A;  3LDW A;  5DJP F;  3LVS A;  3VJB A;  4LOB A;  5EAT A;  3APZ A;  4KUX A;  3WEJ A;  5IK6 A;  4KVW A;  3WEK A;  2H8O A;  5E8H A;  5CG6 A;  2E8V A;  1V4E A;  3KBK A;  2PS8 A;  3OYR A;  1YHM A;  4OMH A;  4RXC A;  3ZMB A;  1UBV A;  5DGM F;  4MC3 A;  5IK9 A;  4KWD A;  4LLT A;  3AQB B;  3KB9 A;  3P8L A;  5EAS A;  3ZL6 A;  1HX9 A;  5B0L A;  1VG6 A;  4KPD A;  1V4K A;  5CG5 A;  1FPS A;  4LUU A;  5H9D A;  3ACX A;  4NFI F;  5DGN F;  2E95 A;  5I1U A;  3LLW A;  2Z4W A;  1UBW A;  2J1P A;  3KRF A;  5E8L A;  3PYB A;  3LGK A;  4RXD A;  2FOR A;  3WCH A;  2I19 A;  2F8C F;  3DYF A;  3M9U A;  2Z52 A;  3N5H F;  3N1W F;  1HM7 A;  1HXA A;  2AZL A;  3WCD A;  3QQV A;  2OA6 A;  3WCG A;  5ILD A;  3KRF B;  5JV2 F;  3W7F A;  5IL3 A;  3SDT A;  2ZEV A; 
#chains in the Genus database with same CATH topology
 2FTZ A;  5IVG A;  3UCA A;  3Q30 A;  1DI1 A;  1YV5 A;  1RQI A;  3Q1O A;  1VG2 A;  3MZV A;  5DIQ F;  3WCL A;  2ZCS A;  2ZEU A;  3ACY A;  4KPJ A;  3V66 A;  1YYT A;  3S4J A;  4RXE A;  3OAC A;  3TC1 A;  4E1E A;  3AQC B;  4LPH F;  1YYU A;  1JFA A;  1VG4 A;  4E9U A;  4N9U A;  4E9Z A;  1N21 A;  5AYP A;  2J1O A;  4NG6 A;  5DHI A;  3LG5 A;  3VJ9 A;  2VF6 A;  2Z4Z A;  4RYP A;  2AZK A;  5EAU A;  5HN7 A;  2AEK A;  2E91 A;  4QPF A;  2F8Z F;  5HN8 A;  3OAC B;  4N1Z F;  4LFV F;  4MC0 A;  3WEF A;  1WKZ A;  2Q58 A;  3KRO A;  3N45 F;  4KVY A;  1YYS A;  1V4I A;  4MC8 A;  5IMN A;  3N3L F;  3PH7 A;  5IMI A;  5A0I A;  4P0V A;  4HD1 A;  2Z4X A;  5KSX F;  3PYA A;  2Q9Y A;  4NFJ F;  2OGD A;  3B7L A;  1YYR A;  3PDE A;  3KRO B;  3VJ8 A;  5IN8 A;  3WJO A;  3WJK A;  1YQ7 A;  3N46 F;  3RBM A;  3CC9 A;  4F62 A;  3LOM A;  1N22 A;  4DEM F;  2Z7H A;  2F89 F;  3SDQ A;  3P5P A;  4OGU A;  3DYH A;  3P8R A;  3DYG A;  4KQS A;  2AET A;  5IL8 A;  3PKO A;  4NKF A;  4H5E F;  4EA1 A;  3WCA A;  4LLS A;  4LZC A;  4PVX F;  1EZF A;  5JUZ F;  5IK0 A;  2PS4 A;  1UBY A;  1N24 A;  4XQS F;  4JVJ F;  4RXA A;  2ZY1 A;  4LFE A;  3G4F A;  2Q9Z A;  2E92 A;  3M01 A;  4PVY F;  2F92 F;  3LGZ B;  3CKE A;  5B01 A;  3N0G A;  1YHK A;  5DJR F;  3RYW A;  3G4D A;  2ZCQ A;  4NUA A;  1HXC A;  3N3D A;  4DXJ A;  3CP6 A;  4GP1 A;  4RNQ A;  2E4O A;  3VJA A;  2PS6 A;  2PS5 A;  3LK5 A;  5IKA A;  1JFG A;  3IBA A;  5B0J A;  3LSN A;  2OPN A;  1YJ4 A;  4GA3 A;  1WMW A;  2Z4V A;  3KRP A;  3AE0 A;  3S9V A;  4EA2 A;  5IM1 A;  3TFN A;  3IPI A;  4JXN A;  4DWB A;  4FP4 A;  3Q2Z A;  2J5C A;  5A0K A;  3WE9 A;  4QXS F;  2Z4Y A;  4L2X F;  1RTR A;  3KRP B;  2E93 A;  5DHK A;  2AZJ A;  4FJQ A;  4GAX A;  4NKE A;  3TFV A;  3Q2Q A;  2ZCR A;  2O1O A;  3EFQ A;  3LMD A;  1HXG A;  3RMG A;  3VJC A;  4F6X A;  3N0F A;  3LJI A;  5ER8 A;  4DWG A;  5HN9 A;  1HM4 A;  4XQT F;  4XQR F;  4Q23 A;  3WCF A;  3KRC A;  4LTV A;  3WCM A;  4LFG A;  2E90 A;  3ID0 A;  4KQ5 A;  1V4J A;  3OAB A;  4UMJ A;  5AEL A;  4JZX A;  4KK2 A;  5DJV F;  5B03 A;  1N23 A;  4LA6 A;  3KRC B;  4LIX A;  4LPG F;  2Z7I A;  4P0W A;  3VJE A;  1UBX A;  3WSA A;  3SAE A;  3ACW A;  2ZCO A;  2E8X A;  3BNY A;  5AFX A;  4P0X A;  3ICZ A;  3OAB B;  1YHL A;  1V4H A;  2F7M F;  3WSB A;  4LXW A;  4KVD A;  4F6V A;  5IMP A;  3WC9 A;  3NRI A;  4ZQ8 A;  4KKM A;  4KFA A;  5B0M A;  5ERN A;  1PS1 A;  5JV0 F;  5A0J A;  1VG3 A;  5C05 A;  1N20 A;  3MAV A;  3ZCD A;  3WCI A;  5E8K A;  3ZMC A;  3M0G A;  4JXY A;  3N6K F;  3RYE A;  1WL2 A;  3ICN A;  4DI5 A;  2P1C A;  3SDU A;  3ASX A;  1WL1 A;  5ILZ A;  3SDV A;  2PS7 A;  2ONH A;  1WL3 A;  2RAH A;  3WEG A;  4LZ0 A;  5DW7 A;  3EZ3 A;  3M00 A;  3WJN A;  2F94 F;  3P5R A;  1KIZ A;  2E94 A;  5AHU B;  3M02 A;  1YYQ A;  2Z78 A;  5JA0 F;  3WEH A;  3N5J F;  2Q80 A;  1KIY A;  3NPK A;  1N1B A;  3ZOU A;  3NPR A;  5ERO A;  1DGP A;  5DZ2 A;  3BNX A;  3AQ0 A;  5IKH A;  5B02 A;  5B00 A;  4JYX A;  3V1X A;  1VG7 A;  5HNA A;  4NFK F;  5ILH A;  4DZW A;  5JV1 F;  3WCB A;  3N49 F;  4GP2 A;  2E8U A;  4JZB A;  4H5C F;  4K10 A;  4OKZ A;  1RQJ A;  4KQU A;  1ZW5 A;  3N1V F;  2ONG A;  4OMG A;  2Z50 A;  3ICM A;  3V1V A;  3TFP A;  3LZ9 A;  4LA5 A;  4OKM A;  3P41 A;  4EA0 A;  3TS7 A;  3KRA A;  4WK5 A;  4LZ3 A;  3WEI A;  3LEE A;  5ERM A;  3WCJ A;  4H5D F;  2EWG A;  2E8W A;  1WY0 A;  5ILY A;  5B0I A;  1WL0 A;  3SDR A;  2QIS A;  5ILJ A;  3KRA B;  2E8T A;  3ICK A;  3NF2 A;  1N1Z A;  4KVI A;  5B0K A;  5ILK A;  5DGS F;  3EGT A;  4LTZ A;  2OPM A;  2F9K F;  2AEL A;  3QKC A;  3VJD A;  3ADZ A;  5ILI A;  3WCE A;  3WCC A;  2DH4 A;  4DHD A;  3LDW A;  5DJP F;  3LVS A;  3VJB A;  4LOB A;  5EAT A;  3APZ A;  4KUX A;  3WEJ A;  5IK6 A;  4KVW A;  3WEK A;  2H8O A;  5E8H A;  5CG6 A;  2E8V A;  1V4E A;  3KBK A;  2PS8 A;  3OYR A;  1YHM A;  4OMH A;  4RXC A;  3ZMB A;  1UBV A;  5DGM F;  4MC3 A;  5IK9 A;  4KWD A;  4LLT A;  3AQB B;  3KB9 A;  3P8L A;  5EAS A;  3ZL6 A;  1HX9 A;  5B0L A;  1VG6 A;  4KPD A;  1V4K A;  5CG5 A;  1FPS A;  4LUU A;  5H9D A;  3ACX A;  4NFI F;  5DGN F;  2E95 A;  5I1U A;  3LLW A;  2Z4W A;  1UBW A;  2J1P A;  3KRF A;  5E8L A;  3PYB A;  3LGK A;  4RXD A;  2FOR A;  3WCH A;  2I19 A;  2F8C F;  3DYF A;  3M9U A;  2Z52 A;  3N5H F;  3N1W F;  1HM7 A;  1HXA A;  2AZL A;  3WCD A;  3QQV A;  2OA6 A;  3WCG A;  5ILD A;  3KRF B;  5JV2 F;  3W7F A;  5IL3 A;  3SDT A;  2ZEV A; 
#chains in the Genus database with same CATH homology
 2FTZ A;  5IVG A;  3UCA A;  3Q30 A;  1DI1 A;  1YV5 A;  1RQI A;  3Q1O A;  1VG2 A;  3MZV A;  5DIQ F;  3WCL A;  2ZCS A;  2ZEU A;  3ACY A;  4KPJ A;  3V66 A;  1YYT A;  3S4J A;  4RXE A;  3OAC A;  3TC1 A;  4E1E A;  3AQC B;  4LPH F;  1YYU A;  1JFA A;  1VG4 A;  4E9U A;  4N9U A;  4E9Z A;  1N21 A;  5AYP A;  2J1O A;  4NG6 A;  5DHI A;  3LG5 A;  3VJ9 A;  2VF6 A;  2Z4Z A;  4RYP A;  2AZK A;  5EAU A;  5HN7 A;  2AEK A;  2E91 A;  4QPF A;  2F8Z F;  5HN8 A;  3OAC B;  4N1Z F;  4LFV F;  4MC0 A;  3WEF A;  1WKZ A;  2Q58 A;  3KRO A;  3N45 F;  4KVY A;  1YYS A;  1V4I A;  4MC8 A;  5IMN A;  3N3L F;  3PH7 A;  5IMI A;  5A0I A;  4P0V A;  4HD1 A;  2Z4X A;  5KSX F;  3PYA A;  2Q9Y A;  4NFJ F;  2OGD A;  3B7L A;  1YYR A;  3PDE A;  3KRO B;  3VJ8 A;  5IN8 A;  3WJO A;  3WJK A;  1YQ7 A;  3N46 F;  3RBM A;  3CC9 A;  4F62 A;  3LOM A;  1N22 A;  4DEM F;  2Z7H A;  2F89 F;  3SDQ A;  3P5P A;  4OGU A;  3DYH A;  3P8R A;  3DYG A;  4KQS A;  2AET A;  5IL8 A;  3PKO A;  4NKF A;  4H5E F;  4EA1 A;  3WCA A;  4LLS A;  4LZC A;  4PVX F;  1EZF A;  5JUZ F;  5IK0 A;  2PS4 A;  1UBY A;  1N24 A;  4XQS F;  4JVJ F;  4RXA A;  2ZY1 A;  4LFE A;  3G4F A;  2Q9Z A;  2E92 A;  3M01 A;  4PVY F;  2F92 F;  3LGZ B;  3CKE A;  5B01 A;  3N0G A;  1YHK A;  5DJR F;  3RYW A;  3G4D A;  2ZCQ A;  4NUA A;  1HXC A;  3N3D A;  4DXJ A;  3CP6 A;  4GP1 A;  4RNQ A;  2E4O A;  3VJA A;  2PS6 A;  2PS5 A;  3LK5 A;  5IKA A;  1JFG A;  3IBA A;  5B0J A;  3LSN A;  2OPN A;  1YJ4 A;  4GA3 A;  1WMW A;  2Z4V A;  3KRP A;  3AE0 A;  3S9V A;  4EA2 A;  5IM1 A;  3TFN A;  3IPI A;  4JXN A;  4DWB A;  4FP4 A;  3Q2Z A;  2J5C A;  5A0K A;  3WE9 A;  4QXS F;  2Z4Y A;  4L2X F;  1RTR A;  3KRP B;  2E93 A;  5DHK A;  2AZJ A;  4FJQ A;  4GAX A;  4NKE A;  3TFV A;  3Q2Q A;  2ZCR A;  2O1O A;  3EFQ A;  3LMD A;  1HXG A;  3RMG A;  3VJC A;  4F6X A;  3N0F A;  3LJI A;  5ER8 A;  4DWG A;  5HN9 A;  1HM4 A;  4XQT F;  4XQR F;  4Q23 A;  3WCF A;  3KRC A;  4LTV A;  3WCM A;  4LFG A;  2E90 A;  3ID0 A;  4KQ5 A;  1V4J A;  3OAB A;  4UMJ A;  5AEL A;  4JZX A;  4KK2 A;  5DJV F;  5B03 A;  1N23 A;  4LA6 A;  3KRC B;  4LIX A;  4LPG F;  2Z7I A;  4P0W A;  3VJE A;  1UBX A;  3WSA A;  3SAE A;  3ACW A;  2ZCO A;  2E8X A;  3BNY A;  5AFX A;  4P0X A;  3ICZ A;  3OAB B;  1YHL A;  1V4H A;  2F7M F;  3WSB A;  4LXW A;  4KVD A;  4F6V A;  5IMP A;  3WC9 A;  3NRI A;  4ZQ8 A;  4KKM A;  4KFA A;  5B0M A;  5ERN A;  1PS1 A;  5JV0 F;  5A0J A;  1VG3 A;  5C05 A;  1N20 A;  3MAV A;  3ZCD A;  3WCI A;  5E8K A;  3ZMC A;  3M0G A;  4JXY A;  3N6K F;  3RYE A;  1WL2 A;  3ICN A;  4DI5 A;  2P1C A;  3SDU A;  3ASX A;  1WL1 A;  5ILZ A;  3SDV A;  2PS7 A;  2ONH A;  1WL3 A;  2RAH A;  3WEG A;  4LZ0 A;  5DW7 A;  3EZ3 A;  3M00 A;  3WJN A;  2F94 F;  3P5R A;  1KIZ A;  2E94 A;  5AHU B;  3M02 A;  1YYQ A;  2Z78 A;  5JA0 F;  3WEH A;  3N5J F;  2Q80 A;  1KIY A;  3NPK A;  1N1B A;  3ZOU A;  3NPR A;  5ERO A;  1DGP A;  5DZ2 A;  3BNX A;  3AQ0 A;  5IKH A;  5B02 A;  5B00 A;  4JYX A;  3V1X A;  1VG7 A;  5HNA A;  4NFK F;  5ILH A;  4DZW A;  5JV1 F;  3WCB A;  3N49 F;  4GP2 A;  2E8U A;  4JZB A;  4H5C F;  4K10 A;  4OKZ A;  1RQJ A;  4KQU A;  1ZW5 A;  3N1V F;  2ONG A;  4OMG A;  2Z50 A;  3ICM A;  3V1V A;  3TFP A;  3LZ9 A;  4LA5 A;  4OKM A;  3P41 A;  4EA0 A;  3TS7 A;  3KRA A;  4WK5 A;  4LZ3 A;  3WEI A;  3LEE A;  5ERM A;  3WCJ A;  4H5D F;  2EWG A;  2E8W A;  1WY0 A;  5ILY A;  5B0I A;  1WL0 A;  3SDR A;  2QIS A;  5ILJ A;  3KRA B;  2E8T A;  3ICK A;  3NF2 A;  1N1Z A;  4KVI A;  5B0K A;  5ILK A;  5DGS F;  3EGT A;  4LTZ A;  2OPM A;  2F9K F;  2AEL A;  3QKC A;  3VJD A;  3ADZ A;  5ILI A;  3WCE A;  3WCC A;  2DH4 A;  4DHD A;  3LDW A;  5DJP F;  3LVS A;  3VJB A;  4LOB A;  5EAT A;  3APZ A;  4KUX A;  3WEJ A;  5IK6 A;  4KVW A;  3WEK A;  2H8O A;  5E8H A;  5CG6 A;  2E8V A;  1V4E A;  3KBK A;  2PS8 A;  3OYR A;  1YHM A;  4OMH A;  4RXC A;  3ZMB A;  1UBV A;  5DGM F;  4MC3 A;  5IK9 A;  4KWD A;  4LLT A;  3AQB B;  3KB9 A;  3P8L A;  5EAS A;  3ZL6 A;  1HX9 A;  5B0L A;  1VG6 A;  4KPD A;  1V4K A;  5CG5 A;  1FPS A;  4LUU A;  5H9D A;  3ACX A;  4NFI F;  5DGN F;  2E95 A;  5I1U A;  3LLW A;  2Z4W A;  1UBW A;  2J1P A;  3KRF A;  5E8L A;  3PYB A;  3LGK A;  4RXD A;  2FOR A;  3WCH A;  2I19 A;  2F8C F;  3DYF A;  3M9U A;  2Z52 A;  3N5H F;  3N1W F;  1HM7 A;  1HXA A;  2AZL A;  3WCD A;  3QQV A;  2OA6 A;  3WCG A;  5ILD A;  3KRF B;  5JV2 F;  3W7F A;  5IL3 A;  3SDT A;  2ZEV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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