4E1EA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-hexylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
361
structure length
361
Chain Sequence
ASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
molecule tags Transferase/transferase inhibitor
total genus 143
structure length 361
sequence length 361
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4e1eA00
4LZ3A 5IM1A 3SDQA 2J1OA 4GP1A 3G4DA 4LLTA 3N45F 3P41A 4RXEA 3ZL6A 3N46F 4OMGA 3ICMA 2Z50A 5CG5A 3WCMA 1N22A 3EFQA 2AZKA 1RQIA 3V66A 3VJEA 1VG6A 4LTVA 1N1BA 2I19A 5ILHA 1JFAA 3TFPA 1N1ZA 4NG6A 3PH7A 2Z7HA 3WEIA 2F8CF 2RAHA 5AYPA 5ILZA 1YHMA 4P0VA 5IKHA 3DYHA 5IMIA 2ZCRA 5B0MA 3RYEA 5IK9A 2O1OA 3SDVA 3ACYA 4KKMA 1EZFA 4OMHA 3S4JA 2AELA 3TS7A 1VG2A 4KPDA 5A0KA 3KRPA 1FPSA 2AZJA 2P1CA 3KRCA 3KBKA 5IK6A 3SDTA 3NPKA 5HN9A 1WL2A 3UCAA 4LFGA 4HD1A 3M02A 4DWGA 4EA1A 2E92A 2F92F 1YHLA 3Q30A 1YYQA 4KQ5A 3EGTA 4JZBA 4EA0A 3KB9A 2Q9YA 3LGKA 3WC9A 3NF2A 4N1ZF 4OGUA 4KQUA 3KRFA 3W7FA 3WJOA 1YHKA 3ZMBA 4DEMF 3ICZA 1YYUA 4XQRF 4JVJF 1YQ7A 3QKCA 5B0IA 5A0IA 2QISA 4H5DF 2ONHA 3G4FA 5IMNA 2ZEVA 4DWBA 2ZCOA 1UBXA 5ERMA 2VF6A 4LUUA 3CC9A 3VJAA 1N23A 3N49F 5E8HA 4GA3A 2OGDA 1VG4A 2E94A 3ASXA 4E9UA 3P5PA 3M0GA 4Q23A 2DH4A 3WCLA 3ACXA 2PS6A 4KQSA 4L2XF 3SAEA 5I1UA 1VG7A 5B0LA 4XQSF 3KRPB 3NRIA 3M01A 4LIXA 1V4HA 3KRCB 3PDEA 2FORA 2PS7A 3AQ0A 3ID0A 4MC8A 2Z7IA 4FP4A 5KSXF 3ADZA 5DZ2A 2J5CA 4FJQA 2E8TA 4QXSF 3ZCDA 5ILDA 2E95A 5ILYA 2FTZA 3APZA 2Z4ZA 4K10A 3VJ8A 4DZWA 3N3LF 3LMDA 3P8RA 2Z4XA 3TC1A 4KVYA 5AHUB 3WCFA 2AETA 4KVIA 2F9KF 1HM4A 5HN8A 1YYSA 3TFNA 5EASA 3EZ3A 5DIQF 3WEKA 4F6XA 3PKOA 4OKZA 1WY0A 3KRFB 5DGMF 3WEHA 1V4KA 4NKEA 1PS1A 4NKFA 2F94F 5ER8A 4KK2A 4LFEA 3N5HF 4P0WA 3PYAA 1N21A 4JYXA 4E9ZA 3LK5A 4RXCA 3N3DA 3ACWA 4JXYA 5DJVF 3LZ9A 4WK5A 3VJBA 4LLSA 1ZW5A 3SDRA 1YV5A 5DW7A 3M9UA 2Q80A 3N5JF 1V4IA 4RXDA 5AELA 1UBYA 3RMGA 3V1VA 5IN8A 4LTZA 4UMJA 1YYTA 2E8UA 5DHKA 1WL0A 2J1PA 5AFXA 5E8KA 5ERNA 5HNAA 4H5CF 5IL8A 4KFAA 3N1WF 3KROB 4PVYF 5EROA 3LOMA 5IVGA 4LXWA 4KWDA 3Q1OA 3DYFA 2E8VA 4LA5A 5B0JA 5B03A 3WE9A 5IKAA 3B7LA 4KVDA 3LVSA 4KVWA 3OACB 3Q2QA 2E8WA 3WJNA 4MC0A 3TFVA 3N0GA 3WCDA 3WCBA 1HXAA 1N20A 3S9VA 3LDWA 1JFGA 2PS5A 3BNXA 2F7MF 1DGPA 1WL3A 2E4OA 5ILJA 4GP2A 4OKMA 3KROA 2ONGA 3RBMA 3DYGA 3WSBA 4NUAA 5IK0A 4LZCA 4RYPA 2E93A 4LPHF 2EWGA 3KRAA 4DI5A 3WEFA 4KUXA 3M00A 4GAXA 5JV1F 2Z4YA 3WCGA 4EA2A 5IL3A 1V4EA 5IMPA 1VG3A 5DGNF 5ILIA 2Z4WA 1DI1A 4LPGF 5B0KA 5CG6A 3OACA 2E90A 5B02A 3QQVA 3RYWA 2PS8A 5HN7A 4QPFA 2Z78A 1HXGA 2OPNA 5EAUA 2F89F 3LLWA 4LZ0A 3WEGA 3WCAA 1HXCA 4MC3A 3OABB 5B00A 3MAVA 3N6KF 3P8LA 1RTRA 2Z52A 3LGZB 1RQJA 2ZEUA 5JA0F 2H8OA 3WCIA 2AZLA 5A0JA 3SDUA 4NFJF 4NFIF 3V1XA 3ZMCA 3LEEA 1KIYA 3WCHA 3PYBA 4XQTF 3Q2ZA 1HX9A 4RXAA 5DHIA 5C05A 5JV2F 1WMWA 1KIZA 3LG5A 5DJPF 3ICNA 3ZOUA 4DHDA 4JXNA 1UBVA 5JUZF 5JV0F 3CKEA 3N0FA 3MZVA 4JZXA 5H9DA 2Z4VA 3IBAA 2ZY1A 1N24A 1HM7A 3VJ9A 3BNYA 3OYRA 3WCCA 5E8LA 5B01A 2OPMA 3OABA 4LFVF 3NPRA 3KRAB 1WL1A 4LA6A 5EATA 4N9UA 2F8ZF 3WCJA 2ZCSA 3P5RA 4H5EF 4F6VA 4PVXF 3WEJA 4E1EA 3IPIA 1WKZA 2PS4A 4RNQA 1YJ4A 3WJKA 2AEKA 4ZQ8A 3WSAA 3LJIA 4LOBA 3CP6A 2OA6A 2ZCQA 4F62A 5ILKA 4DXJA 3VJDA 2Q58A 3AQBB 3N1VF 1UBWA 3VJCA 1YYRA 4KPJA 4P0XA 3WCEA 3LSNA 5DGSF 4NFKF 2Q9ZA 3AE0A 3AQCB 3ICKA 2E8XA 5DJRF 2E91A 1V4JA
chains in the Genus database with same CATH superfamily
4LZ3A 5IM1A 3SDQA 2J1OA 4GP1A 3G4DA 4LLTA 3N45F 3P41A 4RXEA 3ZL6A 3N46F 4OMGA 3ICMA 2Z50A 5CG5A 3WCMA 1N22A 3EFQA 2AZKA 1RQIA 3V66A 3VJEA 1VG6A 4LTVA 1N1BA 2I19A 5ILHA 1JFAA 3TFPA 1N1ZA 4NG6A 3PH7A 2Z7HA 3WEIA 2F8CF 2RAHA 5AYPA 5ILZA 1YHMA 4P0VA 5IKHA 3DYHA 5IMIA 2ZCRA 5B0MA 3RYEA 5IK9A 2O1OA 3SDVA 3ACYA 4KKMA 1EZFA 4OMHA 3S4JA 2AELA 3TS7A 1VG2A 4KPDA 5A0KA 3KRPA 1FPSA 2AZJA 2P1CA 3KRCA 3KBKA 5IK6A 3SDTA 3NPKA 5HN9A 1WL2A 3UCAA 4LFGA 4HD1A 3M02A 4DWGA 4EA1A 2E92A 2F92F 1YHLA 3Q30A 1YYQA 4KQ5A 3EGTA 4JZBA 4EA0A 3KB9A 2Q9YA 3LGKA 3WC9A 3NF2A 4N1ZF 4OGUA 4KQUA 3KRFA 3W7FA 3WJOA 1YHKA 3ZMBA 4DEMF 3ICZA 1YYUA 4XQRF 4JVJF 1YQ7A 3QKCA 5B0IA 5A0IA 2QISA 4H5DF 2ONHA 3G4FA 5IMNA 2ZEVA 4DWBA 2ZCOA 1UBXA 5ERMA 2VF6A 4LUUA 3CC9A 3VJAA 1N23A 3N49F 5E8HA 4GA3A 2OGDA 1VG4A 2E94A 3ASXA 4E9UA 3P5PA 3M0GA 4Q23A 2DH4A 3WCLA 3ACXA 2PS6A 4KQSA 4L2XF 3SAEA 5I1UA 1VG7A 5B0LA 4XQSF 3KRPB 3NRIA 3M01A 4LIXA 1V4HA 3KRCB 3PDEA 2FORA 2PS7A 3AQ0A 3ID0A 4MC8A 2Z7IA 4FP4A 5KSXF 3ADZA 5DZ2A 2J5CA 4FJQA 2E8TA 4QXSF 3ZCDA 5ILDA 2E95A 5ILYA 2FTZA 3APZA 2Z4ZA 4K10A 3VJ8A 4DZWA 3N3LF 3LMDA 3P8RA 2Z4XA 3TC1A 4KVYA 5AHUB 3WCFA 2AETA 4KVIA 2F9KF 1HM4A 5HN8A 1YYSA 3TFNA 5EASA 3EZ3A 5DIQF 3WEKA 4F6XA 3PKOA 4OKZA 1WY0A 3KRFB 5DGMF 3WEHA 1V4KA 4NKEA 1PS1A 4NKFA 2F94F 5ER8A 4KK2A 4LFEA 3N5HF 4P0WA 3PYAA 1N21A 4JYXA 4E9ZA 3LK5A 4RXCA 3N3DA 3ACWA 4JXYA 5DJVF 3LZ9A 4WK5A 3VJBA 4LLSA 1ZW5A 3SDRA 1YV5A 5DW7A 3M9UA 2Q80A 3N5JF 1V4IA 4RXDA 5AELA 1UBYA 3RMGA 3V1VA 5IN8A 4LTZA 4UMJA 1YYTA 2E8UA 5DHKA 1WL0A 2J1PA 5AFXA 5E8KA 5ERNA 5HNAA 4H5CF 5IL8A 4KFAA 3N1WF 3KROB 4PVYF 5EROA 3LOMA 5IVGA 4LXWA 4KWDA 3Q1OA 3DYFA 2E8VA 4LA5A 5B0JA 5B03A 3WE9A 5IKAA 3B7LA 4KVDA 3LVSA 4KVWA 3OACB 3Q2QA 2E8WA 3WJNA 4MC0A 3TFVA 3N0GA 3WCDA 3WCBA 1HXAA 1N20A 3S9VA 3LDWA 1JFGA 2PS5A 3BNXA 2F7MF 1DGPA 1WL3A 2E4OA 5ILJA 4GP2A 4OKMA 3KROA 2ONGA 3RBMA 3DYGA 3WSBA 4NUAA 5IK0A 4LZCA 4RYPA 2E93A 4LPHF 2EWGA 3KRAA 4DI5A 3WEFA 4KUXA 3M00A 4GAXA 5JV1F 2Z4YA 3WCGA 4EA2A 5IL3A 1V4EA 5IMPA 1VG3A 5DGNF 5ILIA 2Z4WA 1DI1A 4LPGF 5B0KA 5CG6A 3OACA 2E90A 5B02A 3QQVA 3RYWA 2PS8A 5HN7A 4QPFA 2Z78A 1HXGA 2OPNA 5EAUA 2F89F 3LLWA 4LZ0A 3WEGA 3WCAA 1HXCA 4MC3A 3OABB 5B00A 3MAVA 3N6KF 3P8LA 1RTRA 2Z52A 3LGZB 1RQJA 2ZEUA 5JA0F 2H8OA 3WCIA 2AZLA 5A0JA 3SDUA 4NFJF 4NFIF 3V1XA 3ZMCA 3LEEA 1KIYA 3WCHA 3PYBA 4XQTF 3Q2ZA 1HX9A 4RXAA 5DHIA 5C05A 5JV2F 1WMWA 1KIZA 3LG5A 5DJPF 3ICNA 3ZOUA 4DHDA 4JXNA 1UBVA 5JUZF 5JV0F 3CKEA 3N0FA 3MZVA 4JZXA 5H9DA 2Z4VA 3IBAA 2ZY1A 1N24A 1HM7A 3VJ9A 3BNYA 3OYRA 3WCCA 5E8LA 5B01A 2OPMA 3OABA 4LFVF 3NPRA 3KRAB 1WL1A 4LA6A 5EATA 4N9UA 2F8ZF 3WCJA 2ZCSA 3P5RA 4H5EF 4F6VA 4PVXF 3WEJA 4E1EA 3IPIA 1WKZA 2PS4A 4RNQA 1YJ4A 3WJKA 2AEKA 4ZQ8A 3WSAA 3LJIA 4LOBA 3CP6A 2OA6A 2ZCQA 4F62A 5ILKA 4DXJA 3VJDA 2Q58A 3AQBB 3N1VF 1UBWA 3VJCA 1YYRA 4KPJA 4P0XA 3WCEA 3LSNA 5DGSF 4NFKF 2Q9ZA 3AE0A 3AQCB 3ICKA 2E8XA 5DJRF 2E91A 1V4JA
chains in the Genus database with same CATH topology
4LZ3A 5IM1A 3SDQA 2J1OA 4GP1A 3G4DA 4LLTA 3N45F 3P41A 4RXEA 3ZL6A 3N46F 4OMGA 3ICMA 2Z50A 5CG5A 3WCMA 1N22A 3EFQA 2AZKA 1RQIA 3V66A 3VJEA 1VG6A 4LTVA 1N1BA 2I19A 5ILHA 1JFAA 3TFPA 1N1ZA 4NG6A 3PH7A 2Z7HA 3WEIA 2F8CF 2RAHA 5AYPA 5ILZA 1YHMA 4P0VA 5IKHA 3DYHA 5IMIA 2ZCRA 5B0MA 3RYEA 5IK9A 2O1OA 3SDVA 3ACYA 4KKMA 1EZFA 4OMHA 3S4JA 2AELA 3TS7A 1VG2A 4KPDA 5A0KA 3KRPA 1FPSA 2AZJA 2P1CA 3KRCA 3KBKA 5IK6A 3SDTA 3NPKA 5HN9A 1WL2A 3UCAA 4LFGA 4HD1A 3M02A 4DWGA 4EA1A 2E92A 2F92F 1YHLA 3Q30A 1YYQA 4KQ5A 3EGTA 4JZBA 4EA0A 3KB9A 2Q9YA 3LGKA 3WC9A 3NF2A 4N1ZF 4OGUA 4KQUA 3KRFA 3W7FA 3WJOA 1YHKA 3ZMBA 4DEMF 3ICZA 1YYUA 4XQRF 4JVJF 1YQ7A 3QKCA 5B0IA 5A0IA 2QISA 4H5DF 2ONHA 3G4FA 5IMNA 2ZEVA 4DWBA 2ZCOA 1UBXA 5ERMA 2VF6A 4LUUA 3CC9A 3VJAA 1N23A 3N49F 5E8HA 4GA3A 2OGDA 1VG4A 2E94A 3ASXA 4E9UA 3P5PA 3M0GA 4Q23A 2DH4A 3WCLA 3ACXA 2PS6A 4KQSA 4L2XF 3SAEA 5I1UA 1VG7A 5B0LA 4XQSF 3KRPB 3NRIA 3M01A 4LIXA 1V4HA 3KRCB 3PDEA 2FORA 2PS7A 3AQ0A 3ID0A 4MC8A 2Z7IA 4FP4A 5KSXF 3ADZA 5DZ2A 2J5CA 4FJQA 2E8TA 4QXSF 3ZCDA 5ILDA 2E95A 5ILYA 2FTZA 3APZA 2Z4ZA 4K10A 3VJ8A 4DZWA 3N3LF 3LMDA 3P8RA 2Z4XA 3TC1A 4KVYA 5AHUB 3WCFA 2AETA 4KVIA 2F9KF 1HM4A 5HN8A 1YYSA 3TFNA 5EASA 3EZ3A 5DIQF 3WEKA 4F6XA 3PKOA 4OKZA 1WY0A 3KRFB 5DGMF 3WEHA 1V4KA 4NKEA 1PS1A 4NKFA 2F94F 5ER8A 4KK2A 4LFEA 3N5HF 4P0WA 3PYAA 1N21A 4JYXA 4E9ZA 3LK5A 4RXCA 3N3DA 3ACWA 4JXYA 5DJVF 3LZ9A 4WK5A 3VJBA 4LLSA 1ZW5A 3SDRA 1YV5A 5DW7A 3M9UA 2Q80A 3N5JF 1V4IA 4RXDA 5AELA 1UBYA 3RMGA 3V1VA 5IN8A 4LTZA 4UMJA 1YYTA 2E8UA 5DHKA 1WL0A 2J1PA 5AFXA 5E8KA 5ERNA 5HNAA 4H5CF 5IL8A 4KFAA 3N1WF 3KROB 4PVYF 5EROA 3LOMA 5IVGA 4LXWA 4KWDA 3Q1OA 3DYFA 2E8VA 4LA5A 5B0JA 5B03A 3WE9A 5IKAA 3B7LA 4KVDA 3LVSA 4KVWA 3OACB 3Q2QA 2E8WA 3WJNA 4MC0A 3TFVA 3N0GA 3WCDA 3WCBA 1HXAA 1N20A 3S9VA 3LDWA 1JFGA 2PS5A 3BNXA 2F7MF 1DGPA 1WL3A 2E4OA 5ILJA 4GP2A 4OKMA 3KROA 2ONGA 3RBMA 3DYGA 3WSBA 4NUAA 5IK0A 4LZCA 4RYPA 2E93A 4LPHF 2EWGA 3KRAA 4DI5A 3WEFA 4KUXA 3M00A 4GAXA 5JV1F 2Z4YA 3WCGA 4EA2A 5IL3A 1V4EA 5IMPA 1VG3A 5DGNF 5ILIA 2Z4WA 1DI1A 4LPGF 5B0KA 5CG6A 3OACA 2E90A 5B02A 3QQVA 3RYWA 2PS8A 5HN7A 4QPFA 2Z78A 1HXGA 2OPNA 5EAUA 2F89F 3LLWA 4LZ0A 3WEGA 3WCAA 1HXCA 4MC3A 3OABB 5B00A 3MAVA 3N6KF 3P8LA 1RTRA 2Z52A 3LGZB 1RQJA 2ZEUA 5JA0F 2H8OA 3WCIA 2AZLA 5A0JA 3SDUA 4NFJF 4NFIF 3V1XA 3ZMCA 3LEEA 1KIYA 3WCHA 3PYBA 4XQTF 3Q2ZA 1HX9A 4RXAA 5DHIA 5C05A 5JV2F 1WMWA 1KIZA 3LG5A 5DJPF 3ICNA 3ZOUA 4DHDA 4JXNA 1UBVA 5JUZF 5JV0F 3CKEA 3N0FA 3MZVA 4JZXA 5H9DA 2Z4VA 3IBAA 2ZY1A 1N24A 1HM7A 3VJ9A 3BNYA 3OYRA 3WCCA 5E8LA 5B01A 2OPMA 3OABA 4LFVF 3NPRA 3KRAB 1WL1A 4LA6A 5EATA 4N9UA 2F8ZF 3WCJA 2ZCSA 3P5RA 4H5EF 4F6VA 4PVXF 3WEJA 4E1EA 3IPIA 1WKZA 2PS4A 4RNQA 1YJ4A 3WJKA 2AEKA 4ZQ8A 3WSAA 3LJIA 4LOBA 3CP6A 2OA6A 2ZCQA 4F62A 5ILKA 4DXJA 3VJDA 2Q58A 3AQBB 3N1VF 1UBWA 3VJCA 1YYRA 4KPJA 4P0XA 3WCEA 3LSNA 5DGSF 4NFKF 2Q9ZA 3AE0A 3AQCB 3ICKA 2E8XA 5DJRF 2E91A 1V4JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LZ3 A;  5IM1 A;  3SDQ A;  2J1O A;  4GP1 A;  3G4D A;  4LLT A;  3N45 F;  3P41 A;  4RXE A;  3ZL6 A;  3N46 F;  4OMG A;  3ICM A;  2Z50 A;  5CG5 A;  3WCM A;  1N22 A;  3EFQ A;  2AZK A;  1RQI A;  3V66 A;  3VJE A;  1VG6 A;  4LTV A;  1N1B A;  2I19 A;  5ILH A;  1JFA A;  3TFP A;  1N1Z A;  4NG6 A;  3PH7 A;  2Z7H A;  3WEI A;  2F8C F;  2RAH A;  5AYP A;  5ILZ A;  1YHM A;  4P0V A;  5IKH A;  3DYH A;  5IMI A;  2ZCR A;  5B0M A;  3RYE A;  5IK9 A;  2O1O A;  3SDV A;  3ACY A;  4KKM A;  1EZF A;  4OMH A;  3S4J A;  2AEL A;  3TS7 A;  1VG2 A;  4KPD A;  5A0K A;  3KRP A;  1FPS A;  2AZJ A;  2P1C A;  3KRC A;  3KBK A;  5IK6 A;  3SDT A;  3NPK A;  5HN9 A;  1WL2 A;  3UCA A;  4LFG A;  4HD1 A;  3M02 A;  4DWG A;  4EA1 A;  2E92 A;  2F92 F;  1YHL A;  3Q30 A;  1YYQ A;  4KQ5 A;  3EGT A;  4JZB A;  4EA0 A;  3KB9 A;  2Q9Y A;  3LGK A;  3WC9 A;  3NF2 A;  4N1Z F;  4OGU A;  4KQU A;  3KRF A;  3W7F A;  3WJO A;  1YHK A;  3ZMB A;  4DEM F;  3ICZ A;  1YYU A;  4XQR F;  4JVJ F;  1YQ7 A;  3QKC A;  5B0I A;  5A0I A;  2QIS A;  4H5D F;  2ONH A;  3G4F A;  5IMN A;  2ZEV A;  4DWB A;  2ZCO A;  1UBX A;  5ERM A;  2VF6 A;  4LUU A;  3CC9 A;  3VJA A;  1N23 A;  3N49 F;  5E8H A;  4GA3 A;  2OGD A;  1VG4 A;  2E94 A;  3ASX A;  4E9U A;  3P5P A;  3M0G A;  4Q23 A;  2DH4 A;  3WCL A;  3ACX A;  2PS6 A;  4KQS A;  4L2X F;  3SAE A;  5I1U A;  1VG7 A;  5B0L A;  4XQS F;  3KRP B;  3NRI A;  3M01 A;  4LIX A;  1V4H A;  3KRC B;  3PDE A;  2FOR A;  2PS7 A;  3AQ0 A;  3ID0 A;  4MC8 A;  2Z7I A;  4FP4 A;  5KSX F;  3ADZ A;  5DZ2 A;  2J5C A;  4FJQ A;  2E8T A;  4QXS F;  3ZCD A;  5ILD A;  2E95 A;  5ILY A;  2FTZ A;  3APZ A;  2Z4Z A;  4K10 A;  3VJ8 A;  4DZW A;  3N3L F;  3LMD A;  3P8R A;  2Z4X A;  3TC1 A;  4KVY A;  5AHU B;  3WCF A;  2AET A;  4KVI A;  2F9K F;  1HM4 A;  5HN8 A;  1YYS A;  3TFN A;  5EAS A;  3EZ3 A;  5DIQ F;  3WEK A;  4F6X A;  3PKO A;  4OKZ A;  1WY0 A;  3KRF B;  5DGM F;  3WEH A;  1V4K A;  4NKE A;  1PS1 A;  4NKF A;  2F94 F;  5ER8 A;  4KK2 A;  4LFE A;  3N5H F;  4P0W A;  3PYA A;  1N21 A;  4JYX A;  4E9Z A;  3LK5 A;  4RXC A;  3N3D A;  3ACW A;  4JXY A;  5DJV F;  3LZ9 A;  4WK5 A;  3VJB A;  4LLS A;  1ZW5 A;  3SDR A;  1YV5 A;  5DW7 A;  3M9U A;  2Q80 A;  3N5J F;  1V4I A;  4RXD A;  5AEL A;  1UBY A;  3RMG A;  3V1V A;  5IN8 A;  4LTZ A;  4UMJ A;  1YYT A;  2E8U A;  5DHK A;  1WL0 A;  2J1P A;  5AFX A;  5E8K A;  5ERN A;  5HNA A;  4H5C F;  5IL8 A;  4KFA A;  3N1W F;  3KRO B;  4PVY F;  5ERO A;  3LOM A;  5IVG A;  4LXW A;  4KWD A;  3Q1O A;  3DYF A;  2E8V A;  4LA5 A;  5B0J A;  5B03 A;  3WE9 A;  5IKA A;  3B7L A;  4KVD A;  3LVS A;  4KVW A;  3OAC B;  3Q2Q A;  2E8W A;  3WJN A;  4MC0 A;  3TFV A;  3N0G A;  3WCD A;  3WCB A;  1HXA A;  1N20 A;  3S9V A;  3LDW A;  1JFG A;  2PS5 A;  3BNX A;  2F7M F;  1DGP A;  1WL3 A;  2E4O A;  5ILJ A;  4GP2 A;  4OKM A;  3KRO A;  2ONG A;  3RBM A;  3DYG A;  3WSB A;  4NUA A;  5IK0 A;  4LZC A;  4RYP A;  2E93 A;  4LPH F;  2EWG A;  3KRA A;  4DI5 A;  3WEF A;  4KUX A;  3M00 A;  4GAX A;  5JV1 F;  2Z4Y A;  3WCG A;  4EA2 A;  5IL3 A;  1V4E A;  5IMP A;  1VG3 A;  5DGN F;  5ILI A;  2Z4W A;  1DI1 A;  4LPG F;  5B0K A;  5CG6 A;  3OAC A;  2E90 A;  5B02 A;  3QQV A;  3RYW A;  2PS8 A;  5HN7 A;  4QPF A;  2Z78 A;  1HXG A;  2OPN A;  5EAU A;  2F89 F;  3LLW A;  4LZ0 A;  3WEG A;  3WCA A;  1HXC A;  4MC3 A;  3OAB B;  5B00 A;  3MAV A;  3N6K F;  3P8L A;  1RTR A;  2Z52 A;  3LGZ B;  1RQJ A;  2ZEU A;  5JA0 F;  2H8O A;  3WCI A;  2AZL A;  5A0J A;  3SDU A;  4NFJ F;  4NFI F;  3V1X A;  3ZMC A;  3LEE A;  1KIY A;  3WCH A;  3PYB A;  4XQT F;  3Q2Z A;  1HX9 A;  4RXA A;  5DHI A;  5C05 A;  5JV2 F;  1WMW A;  1KIZ A;  3LG5 A;  5DJP F;  3ICN A;  3ZOU A;  4DHD A;  4JXN A;  1UBV A;  5JUZ F;  5JV0 F;  3CKE A;  3N0F A;  3MZV A;  4JZX A;  5H9D A;  2Z4V A;  3IBA A;  2ZY1 A;  1N24 A;  1HM7 A;  3VJ9 A;  3BNY A;  3OYR A;  3WCC A;  5E8L A;  5B01 A;  2OPM A;  3OAB A;  4LFV F;  3NPR A;  3KRA B;  1WL1 A;  4LA6 A;  5EAT A;  4N9U A;  2F8Z F;  3WCJ A;  2ZCS A;  3P5R A;  4H5E F;  4F6V A;  4PVX F;  3WEJ A;  4E1E A;  3IPI A;  1WKZ A;  2PS4 A;  4RNQ A;  1YJ4 A;  3WJK A;  2AEK A;  4ZQ8 A;  3WSA A;  3LJI A;  4LOB A;  3CP6 A;  2OA6 A;  2ZCQ A;  4F62 A;  5ILK A;  4DXJ A;  3VJD A;  2Q58 A;  3AQB B;  3N1V F;  1UBW A;  3VJC A;  1YYR A;  4KPJ A;  4P0X A;  3WCE A;  3LSN A;  5DGS F;  4NFK F;  2Q9Z A;  3AE0 A;  3AQC B;  3ICK A;  2E8X A;  5DJR F;  2E91 A;  1V4J A; 
#chains in the Genus database with same CATH topology
 4LZ3 A;  5IM1 A;  3SDQ A;  2J1O A;  4GP1 A;  3G4D A;  4LLT A;  3N45 F;  3P41 A;  4RXE A;  3ZL6 A;  3N46 F;  4OMG A;  3ICM A;  2Z50 A;  5CG5 A;  3WCM A;  1N22 A;  3EFQ A;  2AZK A;  1RQI A;  3V66 A;  3VJE A;  1VG6 A;  4LTV A;  1N1B A;  2I19 A;  5ILH A;  1JFA A;  3TFP A;  1N1Z A;  4NG6 A;  3PH7 A;  2Z7H A;  3WEI A;  2F8C F;  2RAH A;  5AYP A;  5ILZ A;  1YHM A;  4P0V A;  5IKH A;  3DYH A;  5IMI A;  2ZCR A;  5B0M A;  3RYE A;  5IK9 A;  2O1O A;  3SDV A;  3ACY A;  4KKM A;  1EZF A;  4OMH A;  3S4J A;  2AEL A;  3TS7 A;  1VG2 A;  4KPD A;  5A0K A;  3KRP A;  1FPS A;  2AZJ A;  2P1C A;  3KRC A;  3KBK A;  5IK6 A;  3SDT A;  3NPK A;  5HN9 A;  1WL2 A;  3UCA A;  4LFG A;  4HD1 A;  3M02 A;  4DWG A;  4EA1 A;  2E92 A;  2F92 F;  1YHL A;  3Q30 A;  1YYQ A;  4KQ5 A;  3EGT A;  4JZB A;  4EA0 A;  3KB9 A;  2Q9Y A;  3LGK A;  3WC9 A;  3NF2 A;  4N1Z F;  4OGU A;  4KQU A;  3KRF A;  3W7F A;  3WJO A;  1YHK A;  3ZMB A;  4DEM F;  3ICZ A;  1YYU A;  4XQR F;  4JVJ F;  1YQ7 A;  3QKC A;  5B0I A;  5A0I A;  2QIS A;  4H5D F;  2ONH A;  3G4F A;  5IMN A;  2ZEV A;  4DWB A;  2ZCO A;  1UBX A;  5ERM A;  2VF6 A;  4LUU A;  3CC9 A;  3VJA A;  1N23 A;  3N49 F;  5E8H A;  4GA3 A;  2OGD A;  1VG4 A;  2E94 A;  3ASX A;  4E9U A;  3P5P A;  3M0G A;  4Q23 A;  2DH4 A;  3WCL A;  3ACX A;  2PS6 A;  4KQS A;  4L2X F;  3SAE A;  5I1U A;  1VG7 A;  5B0L A;  4XQS F;  3KRP B;  3NRI A;  3M01 A;  4LIX A;  1V4H A;  3KRC B;  3PDE A;  2FOR A;  2PS7 A;  3AQ0 A;  3ID0 A;  4MC8 A;  2Z7I A;  4FP4 A;  5KSX F;  3ADZ A;  5DZ2 A;  2J5C A;  4FJQ A;  2E8T A;  4QXS F;  3ZCD A;  5ILD A;  2E95 A;  5ILY A;  2FTZ A;  3APZ A;  2Z4Z A;  4K10 A;  3VJ8 A;  4DZW A;  3N3L F;  3LMD A;  3P8R A;  2Z4X A;  3TC1 A;  4KVY A;  5AHU B;  3WCF A;  2AET A;  4KVI A;  2F9K F;  1HM4 A;  5HN8 A;  1YYS A;  3TFN A;  5EAS A;  3EZ3 A;  5DIQ F;  3WEK A;  4F6X A;  3PKO A;  4OKZ A;  1WY0 A;  3KRF B;  5DGM F;  3WEH A;  1V4K A;  4NKE A;  1PS1 A;  4NKF A;  2F94 F;  5ER8 A;  4KK2 A;  4LFE A;  3N5H F;  4P0W A;  3PYA A;  1N21 A;  4JYX A;  4E9Z A;  3LK5 A;  4RXC A;  3N3D A;  3ACW A;  4JXY A;  5DJV F;  3LZ9 A;  4WK5 A;  3VJB A;  4LLS A;  1ZW5 A;  3SDR A;  1YV5 A;  5DW7 A;  3M9U A;  2Q80 A;  3N5J F;  1V4I A;  4RXD A;  5AEL A;  1UBY A;  3RMG A;  3V1V A;  5IN8 A;  4LTZ A;  4UMJ A;  1YYT A;  2E8U A;  5DHK A;  1WL0 A;  2J1P A;  5AFX A;  5E8K A;  5ERN A;  5HNA A;  4H5C F;  5IL8 A;  4KFA A;  3N1W F;  3KRO B;  4PVY F;  5ERO A;  3LOM A;  5IVG A;  4LXW A;  4KWD A;  3Q1O A;  3DYF A;  2E8V A;  4LA5 A;  5B0J A;  5B03 A;  3WE9 A;  5IKA A;  3B7L A;  4KVD A;  3LVS A;  4KVW A;  3OAC B;  3Q2Q A;  2E8W A;  3WJN A;  4MC0 A;  3TFV A;  3N0G A;  3WCD A;  3WCB A;  1HXA A;  1N20 A;  3S9V A;  3LDW A;  1JFG A;  2PS5 A;  3BNX A;  2F7M F;  1DGP A;  1WL3 A;  2E4O A;  5ILJ A;  4GP2 A;  4OKM A;  3KRO A;  2ONG A;  3RBM A;  3DYG A;  3WSB A;  4NUA A;  5IK0 A;  4LZC A;  4RYP A;  2E93 A;  4LPH F;  2EWG A;  3KRA A;  4DI5 A;  3WEF A;  4KUX A;  3M00 A;  4GAX A;  5JV1 F;  2Z4Y A;  3WCG A;  4EA2 A;  5IL3 A;  1V4E A;  5IMP A;  1VG3 A;  5DGN F;  5ILI A;  2Z4W A;  1DI1 A;  4LPG F;  5B0K A;  5CG6 A;  3OAC A;  2E90 A;  5B02 A;  3QQV A;  3RYW A;  2PS8 A;  5HN7 A;  4QPF A;  2Z78 A;  1HXG A;  2OPN A;  5EAU A;  2F89 F;  3LLW A;  4LZ0 A;  3WEG A;  3WCA A;  1HXC A;  4MC3 A;  3OAB B;  5B00 A;  3MAV A;  3N6K F;  3P8L A;  1RTR A;  2Z52 A;  3LGZ B;  1RQJ A;  2ZEU A;  5JA0 F;  2H8O A;  3WCI A;  2AZL A;  5A0J A;  3SDU A;  4NFJ F;  4NFI F;  3V1X A;  3ZMC A;  3LEE A;  1KIY A;  3WCH A;  3PYB A;  4XQT F;  3Q2Z A;  1HX9 A;  4RXA A;  5DHI A;  5C05 A;  5JV2 F;  1WMW A;  1KIZ A;  3LG5 A;  5DJP F;  3ICN A;  3ZOU A;  4DHD A;  4JXN A;  1UBV A;  5JUZ F;  5JV0 F;  3CKE A;  3N0F A;  3MZV A;  4JZX A;  5H9D A;  2Z4V A;  3IBA A;  2ZY1 A;  1N24 A;  1HM7 A;  3VJ9 A;  3BNY A;  3OYR A;  3WCC A;  5E8L A;  5B01 A;  2OPM A;  3OAB A;  4LFV F;  3NPR A;  3KRA B;  1WL1 A;  4LA6 A;  5EAT A;  4N9U A;  2F8Z F;  3WCJ A;  2ZCS A;  3P5R A;  4H5E F;  4F6V A;  4PVX F;  3WEJ A;  4E1E A;  3IPI A;  1WKZ A;  2PS4 A;  4RNQ A;  1YJ4 A;  3WJK A;  2AEK A;  4ZQ8 A;  3WSA A;  3LJI A;  4LOB A;  3CP6 A;  2OA6 A;  2ZCQ A;  4F62 A;  5ILK A;  4DXJ A;  3VJD A;  2Q58 A;  3AQB B;  3N1V F;  1UBW A;  3VJC A;  1YYR A;  4KPJ A;  4P0X A;  3WCE A;  3LSN A;  5DGS F;  4NFK F;  2Q9Z A;  3AE0 A;  3AQC B;  3ICK A;  2E8X A;  5DJR F;  2E91 A;  1V4J A; 
#chains in the Genus database with same CATH homology
 4LZ3 A;  5IM1 A;  3SDQ A;  2J1O A;  4GP1 A;  3G4D A;  4LLT A;  3N45 F;  3P41 A;  4RXE A;  3ZL6 A;  3N46 F;  4OMG A;  3ICM A;  2Z50 A;  5CG5 A;  3WCM A;  1N22 A;  3EFQ A;  2AZK A;  1RQI A;  3V66 A;  3VJE A;  1VG6 A;  4LTV A;  1N1B A;  2I19 A;  5ILH A;  1JFA A;  3TFP A;  1N1Z A;  4NG6 A;  3PH7 A;  2Z7H A;  3WEI A;  2F8C F;  2RAH A;  5AYP A;  5ILZ A;  1YHM A;  4P0V A;  5IKH A;  3DYH A;  5IMI A;  2ZCR A;  5B0M A;  3RYE A;  5IK9 A;  2O1O A;  3SDV A;  3ACY A;  4KKM A;  1EZF A;  4OMH A;  3S4J A;  2AEL A;  3TS7 A;  1VG2 A;  4KPD A;  5A0K A;  3KRP A;  1FPS A;  2AZJ A;  2P1C A;  3KRC A;  3KBK A;  5IK6 A;  3SDT A;  3NPK A;  5HN9 A;  1WL2 A;  3UCA A;  4LFG A;  4HD1 A;  3M02 A;  4DWG A;  4EA1 A;  2E92 A;  2F92 F;  1YHL A;  3Q30 A;  1YYQ A;  4KQ5 A;  3EGT A;  4JZB A;  4EA0 A;  3KB9 A;  2Q9Y A;  3LGK A;  3WC9 A;  3NF2 A;  4N1Z F;  4OGU A;  4KQU A;  3KRF A;  3W7F A;  3WJO A;  1YHK A;  3ZMB A;  4DEM F;  3ICZ A;  1YYU A;  4XQR F;  4JVJ F;  1YQ7 A;  3QKC A;  5B0I A;  5A0I A;  2QIS A;  4H5D F;  2ONH A;  3G4F A;  5IMN A;  2ZEV A;  4DWB A;  2ZCO A;  1UBX A;  5ERM A;  2VF6 A;  4LUU A;  3CC9 A;  3VJA A;  1N23 A;  3N49 F;  5E8H A;  4GA3 A;  2OGD A;  1VG4 A;  2E94 A;  3ASX A;  4E9U A;  3P5P A;  3M0G A;  4Q23 A;  2DH4 A;  3WCL A;  3ACX A;  2PS6 A;  4KQS A;  4L2X F;  3SAE A;  5I1U A;  1VG7 A;  5B0L A;  4XQS F;  3KRP B;  3NRI A;  3M01 A;  4LIX A;  1V4H A;  3KRC B;  3PDE A;  2FOR A;  2PS7 A;  3AQ0 A;  3ID0 A;  4MC8 A;  2Z7I A;  4FP4 A;  5KSX F;  3ADZ A;  5DZ2 A;  2J5C A;  4FJQ A;  2E8T A;  4QXS F;  3ZCD A;  5ILD A;  2E95 A;  5ILY A;  2FTZ A;  3APZ A;  2Z4Z A;  4K10 A;  3VJ8 A;  4DZW A;  3N3L F;  3LMD A;  3P8R A;  2Z4X A;  3TC1 A;  4KVY A;  5AHU B;  3WCF A;  2AET A;  4KVI A;  2F9K F;  1HM4 A;  5HN8 A;  1YYS A;  3TFN A;  5EAS A;  3EZ3 A;  5DIQ F;  3WEK A;  4F6X A;  3PKO A;  4OKZ A;  1WY0 A;  3KRF B;  5DGM F;  3WEH A;  1V4K A;  4NKE A;  1PS1 A;  4NKF A;  2F94 F;  5ER8 A;  4KK2 A;  4LFE A;  3N5H F;  4P0W A;  3PYA A;  1N21 A;  4JYX A;  4E9Z A;  3LK5 A;  4RXC A;  3N3D A;  3ACW A;  4JXY A;  5DJV F;  3LZ9 A;  4WK5 A;  3VJB A;  4LLS A;  1ZW5 A;  3SDR A;  1YV5 A;  5DW7 A;  3M9U A;  2Q80 A;  3N5J F;  1V4I A;  4RXD A;  5AEL A;  1UBY A;  3RMG A;  3V1V A;  5IN8 A;  4LTZ A;  4UMJ A;  1YYT A;  2E8U A;  5DHK A;  1WL0 A;  2J1P A;  5AFX A;  5E8K A;  5ERN A;  5HNA A;  4H5C F;  5IL8 A;  4KFA A;  3N1W F;  3KRO B;  4PVY F;  5ERO A;  3LOM A;  5IVG A;  4LXW A;  4KWD A;  3Q1O A;  3DYF A;  2E8V A;  4LA5 A;  5B0J A;  5B03 A;  3WE9 A;  5IKA A;  3B7L A;  4KVD A;  3LVS A;  4KVW A;  3OAC B;  3Q2Q A;  2E8W A;  3WJN A;  4MC0 A;  3TFV A;  3N0G A;  3WCD A;  3WCB A;  1HXA A;  1N20 A;  3S9V A;  3LDW A;  1JFG A;  2PS5 A;  3BNX A;  2F7M F;  1DGP A;  1WL3 A;  2E4O A;  5ILJ A;  4GP2 A;  4OKM A;  3KRO A;  2ONG A;  3RBM A;  3DYG A;  3WSB A;  4NUA A;  5IK0 A;  4LZC A;  4RYP A;  2E93 A;  4LPH F;  2EWG A;  3KRA A;  4DI5 A;  3WEF A;  4KUX A;  3M00 A;  4GAX A;  5JV1 F;  2Z4Y A;  3WCG A;  4EA2 A;  5IL3 A;  1V4E A;  5IMP A;  1VG3 A;  5DGN F;  5ILI A;  2Z4W A;  1DI1 A;  4LPG F;  5B0K A;  5CG6 A;  3OAC A;  2E90 A;  5B02 A;  3QQV A;  3RYW A;  2PS8 A;  5HN7 A;  4QPF A;  2Z78 A;  1HXG A;  2OPN A;  5EAU A;  2F89 F;  3LLW A;  4LZ0 A;  3WEG A;  3WCA A;  1HXC A;  4MC3 A;  3OAB B;  5B00 A;  3MAV A;  3N6K F;  3P8L A;  1RTR A;  2Z52 A;  3LGZ B;  1RQJ A;  2ZEU A;  5JA0 F;  2H8O A;  3WCI A;  2AZL A;  5A0J A;  3SDU A;  4NFJ F;  4NFI F;  3V1X A;  3ZMC A;  3LEE A;  1KIY A;  3WCH A;  3PYB A;  4XQT F;  3Q2Z A;  1HX9 A;  4RXA A;  5DHI A;  5C05 A;  5JV2 F;  1WMW A;  1KIZ A;  3LG5 A;  5DJP F;  3ICN A;  3ZOU A;  4DHD A;  4JXN A;  1UBV A;  5JUZ F;  5JV0 F;  3CKE A;  3N0F A;  3MZV A;  4JZX A;  5H9D A;  2Z4V A;  3IBA A;  2ZY1 A;  1N24 A;  1HM7 A;  3VJ9 A;  3BNY A;  3OYR A;  3WCC A;  5E8L A;  5B01 A;  2OPM A;  3OAB A;  4LFV F;  3NPR A;  3KRA B;  1WL1 A;  4LA6 A;  5EAT A;  4N9U A;  2F8Z F;  3WCJ A;  2ZCS A;  3P5R A;  4H5E F;  4F6V A;  4PVX F;  3WEJ A;  4E1E A;  3IPI A;  1WKZ A;  2PS4 A;  4RNQ A;  1YJ4 A;  3WJK A;  2AEK A;  4ZQ8 A;  3WSA A;  3LJI A;  4LOB A;  3CP6 A;  2OA6 A;  2ZCQ A;  4F62 A;  5ILK A;  4DXJ A;  3VJD A;  2Q58 A;  3AQB B;  3N1V F;  1UBW A;  3VJC A;  1YYR A;  4KPJ A;  4P0X A;  3WCE A;  3LSN A;  5DGS F;  4NFK F;  2Q9Z A;  3AE0 A;  3AQC B;  3ICK A;  2E8X A;  5DJR F;  2E91 A;  1V4J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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