4DXJA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-propylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 148
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dxjA00
5B0MA 5JUZF 5A0KA 3G4DA 1WL2A 4NFJF 2E91A 2AZJA 4NG6A 1WL0A 5E8LA 4KVIA 4ZQ8A 4FP4A 4RXCA 4OKZA 2Z4ZA 4GAXA 3WEFA 3AQCB 4FJQA 2VF6A 5DGNF 4LA6A 2AZLA 5AYPA 1RQJA 3QKCA 2O1OA 3KRCB 1HXAA 3N6KF 3NPRA 2F7MF 3MZVA 5DIQF 5EROA 3N1VF 1UBXA 2E95A 1YYQA 4F6VA 4Q23A 2AELA 2PS6A 3PKOA 3ICKA 4H5EF 4OGUA 2F89F 3WSBA 5ILDA 4DWGA 2AZKA 2DH4A 2PS5A 4RXAA 4XQTF 1WMWA 5DJRF 3ZL6A 2FTZA 5IMNA 1YYTA 5C05A 3N49F 3ICZA 3MAVA 5B01A 4JXYA 2Z4WA 3KBKA 5DJPF 3WCDA 4F6XA 3KRPB 3W7FA 3WEHA 2J1OA 5DJVF 4OKMA 5B02A 3RYEA 3Q2QA 2H8OA 5AELA 4MC3A 3N5JF 4WK5A 3SDVA 4EA0A 5I1UA 3DYFA 2Q9YA 5IK9A 2QISA 2PS7A 1WKZA 2E8VA 1JFAA 4NKFA 2ZCRA 1RTRA 5IL8A 3BNYA 5IK6A 1YHMA 4KKMA 3WJKA 5JV1F 4NFKF 3P5PA 4DEMF 3SDTA 3RMGA 4LLSA 4DHDA 3OACA 5A0IA 5DHIA 2E94A 2Q9ZA 3VJDA 4JZBA 3LZ9A 3N1WF 1JFGA 5B03A 1VG2A 5B0JA 4KUXA 2RAHA 3WCJA 3PYBA 3V1XA 4MC0A 3IBAA 4DZWA 2E90A 5EASA 2Q80A 3WJOA 5HN9A 1WY0A 1KIYA 3CKEA 3VJ9A 3KB9A 3DYHA 2PS4A 2F8CF 3M01A 5CG5A 4LLTA 3N46F 3IPIA 3KRFA 5KSXF 2ZCSA 1HM7A 3TC1A 4KQ5A 4LFEA 4HD1A 3LVSA 3WCHA 3NF2A 5IN8A 1KIZA 1DGPA 3WCFA 3ZMBA 3BNXA 3ASXA 4DXJA 1N22A 3PH7A 3P8RA 3TFNA 3WCIA 2ZY1A 3LMDA 4JVJF 1HM4A 4LFVF 4GP2A 5IM1A 2Z4XA 3DYGA 5ILYA 2Z52A 2Z4VA 2OPMA 1VG7A 5AFXA 3LJIA 3ACYA 4LOBA 1YJ4A 4LFGA 2J5CA 3PYAA 3N5HF 5HN8A 3ID0A 3WE9A 3ICMA 4NKEA 3WCCA 3WCGA 3Q1OA 1FPSA 5HNAA 3ACWA 3OACB 4QXSF 1HX9A 3OYRA 5DZ2A 3LSNA 4K10A 4LPHF 4E9ZA 3P41A 3SDQA 1V4KA 4KVWA 1DI1A 5IMIA 3M02A 5H9DA 3VJ8A 4LTZA 2ONGA 5IK0A 3AQ0A 5EATA 5JV2F 4PVXF 1RQIA 4P0WA 3KRAA 5ERMA 1VG6A 3LOMA 5ILKA 4RXDA 4EA2A 1UBYA 3WSAA 2F92F 3ZCDA 3LGZB 3KRFB 3WJNA 3SAEA 3WEJA 4E1EA 4RYPA 4KPJA 4KQSA 5B0KA 4LTVA 2OA6A 1V4EA 3WCLA 2ZEUA 2F8ZF 3WCMA 2AETA 3TS7A 5EAUA 4H5CF 5HN7A 4H5DF 4KVYA 1V4JA 2EWGA 5JA0F 4RNQA 5ILZA 2Z78A 1N1BA 3ADZA 5AHUB 1HXGA 3WEGA 4EA1A 3S4JA 1N21A 5IMPA 3N3LF 3LLWA 5CG6A 3M00A 1YYUA 3RYWA 2ZEVA 5ER8A 4KQUA 5ILJA 1PS1A 2J1PA 3VJBA 1N24A 1V4HA 5IVGA 1UBVA 4OMHA 3APZA 3LEEA 3TFPA 1YYRA 5B00A 5E8HA 2ZCOA 3LG5A 5ILIA 3M9UA 5E8KA 3NPKA 3ACXA 3M0GA 4QPFA 5B0IA 2OPNA 4MC8A 5ILHA 3OABA 3KRAB 3NRIA 3QQVA 4OMGA 1UBWA 2PS8A 3B7LA 2Q58A 4KVDA 2E8WA 4KFAA 4JZXA 4P0XA 2E92A 5DGMF 2ZCQA 5IKHA 4N1ZF 4N9UA 3AE0A 3N45F 4LIXA 5DGSF 3N0FA 3PDEA 3SDRA 1N20A 3G4FA 2E93A 2E4OA 4GA3A 3LK5A 3P8LA 4LZCA 1WL3A 3N0GA 2F94F 1V4IA 1YHKA 2P1CA 4LZ0A 3WCBA 3KROA 1YV5A 4KPDA 3EZ3A 4LXWA 3WEKA 4NUAA 3VJCA 4KK2A 5DW7A 4RXEA 4LZ3A 4KWDA 2FORA 3ZOUA 5ERNA 3V66A 3OABB 4F62A 2I19A 1VG3A 3Q2ZA 4JYXA 4DI5A 1VG4A 3Q30A 3WCEA 4LPGF 2E8XA 2AEKA 3ICNA 3RBMA 3VJEA 3WEIA 5A0JA 3KRCA 1N1ZA 3P5RA 1N23A 3CP6A 2Z7IA 5B0LA 5JV0F 1YHLA 3CC9A 4JXNA 4XQSF 4DWBA 3TFVA 3N3DA 2Z4YA 4LUUA 3V1VA 3VJAA 1HXCA 1ZW5A 1EZFA 1YQ7A 2E8UA 2F9KF 3ZMCA 1YYSA 4UMJA 3AQBB 3EFQA 4P0VA 4XQRF 5IL3A 3WC9A 3UCAA 4PVYF 4L2XF 3KRPA 2E8TA 4LA5A 4E9UA 3EGTA 2Z50A 3KROB 2ONHA 1WL1A 5IKAA 3LDWA 3SDUA 4NFIF 4GP1A 2Z7HA 5DHKA 3LGKA 2OGDA 3WCAA 3S9VA
chains in the Genus database with same CATH superfamily
5B0MA 5JUZF 5A0KA 3G4DA 1WL2A 4NFJF 2E91A 2AZJA 4NG6A 1WL0A 5E8LA 4KVIA 4ZQ8A 4FP4A 4RXCA 4OKZA 2Z4ZA 4GAXA 3WEFA 3AQCB 4FJQA 2VF6A 5DGNF 4LA6A 2AZLA 5AYPA 1RQJA 3QKCA 2O1OA 3KRCB 1HXAA 3N6KF 3NPRA 2F7MF 3MZVA 5DIQF 5EROA 3N1VF 1UBXA 2E95A 1YYQA 4F6VA 4Q23A 2AELA 2PS6A 3PKOA 3ICKA 4H5EF 4OGUA 2F89F 3WSBA 5ILDA 4DWGA 2AZKA 2DH4A 2PS5A 4RXAA 4XQTF 1WMWA 5DJRF 3ZL6A 2FTZA 5IMNA 1YYTA 5C05A 3N49F 3ICZA 3MAVA 5B01A 4JXYA 2Z4WA 3KBKA 5DJPF 3WCDA 4F6XA 3KRPB 3W7FA 3WEHA 2J1OA 5DJVF 4OKMA 5B02A 3RYEA 3Q2QA 2H8OA 5AELA 4MC3A 3N5JF 4WK5A 3SDVA 4EA0A 5I1UA 3DYFA 2Q9YA 5IK9A 2QISA 2PS7A 1WKZA 2E8VA 1JFAA 4NKFA 2ZCRA 1RTRA 5IL8A 3BNYA 5IK6A 1YHMA 4KKMA 3WJKA 5JV1F 4NFKF 3P5PA 4DEMF 3SDTA 3RMGA 4LLSA 4DHDA 3OACA 5A0IA 5DHIA 2E94A 2Q9ZA 3VJDA 4JZBA 3LZ9A 3N1WF 1JFGA 5B03A 1VG2A 5B0JA 4KUXA 2RAHA 3WCJA 3PYBA 3V1XA 4MC0A 3IBAA 4DZWA 2E90A 5EASA 2Q80A 3WJOA 5HN9A 1WY0A 1KIYA 3CKEA 3VJ9A 3KB9A 3DYHA 2PS4A 2F8CF 3M01A 5CG5A 4LLTA 3N46F 3IPIA 3KRFA 5KSXF 2ZCSA 1HM7A 3TC1A 4KQ5A 4LFEA 4HD1A 3LVSA 3WCHA 3NF2A 5IN8A 1KIZA 1DGPA 3WCFA 3ZMBA 3BNXA 3ASXA 4DXJA 1N22A 3PH7A 3P8RA 3TFNA 3WCIA 2ZY1A 3LMDA 4JVJF 1HM4A 4LFVF 4GP2A 5IM1A 2Z4XA 3DYGA 5ILYA 2Z52A 2Z4VA 2OPMA 1VG7A 5AFXA 3LJIA 3ACYA 4LOBA 1YJ4A 4LFGA 2J5CA 3PYAA 3N5HF 5HN8A 3ID0A 3WE9A 3ICMA 4NKEA 3WCCA 3WCGA 3Q1OA 1FPSA 5HNAA 3ACWA 3OACB 4QXSF 1HX9A 3OYRA 5DZ2A 3LSNA 4K10A 4LPHF 4E9ZA 3P41A 3SDQA 1V4KA 4KVWA 1DI1A 5IMIA 3M02A 5H9DA 3VJ8A 4LTZA 2ONGA 5IK0A 3AQ0A 5EATA 5JV2F 4PVXF 1RQIA 4P0WA 3KRAA 5ERMA 1VG6A 3LOMA 5ILKA 4RXDA 4EA2A 1UBYA 3WSAA 2F92F 3ZCDA 3LGZB 3KRFB 3WJNA 3SAEA 3WEJA 4E1EA 4RYPA 4KPJA 4KQSA 5B0KA 4LTVA 2OA6A 1V4EA 3WCLA 2ZEUA 2F8ZF 3WCMA 2AETA 3TS7A 5EAUA 4H5CF 5HN7A 4H5DF 4KVYA 1V4JA 2EWGA 5JA0F 4RNQA 5ILZA 2Z78A 1N1BA 3ADZA 5AHUB 1HXGA 3WEGA 4EA1A 3S4JA 1N21A 5IMPA 3N3LF 3LLWA 5CG6A 3M00A 1YYUA 3RYWA 2ZEVA 5ER8A 4KQUA 5ILJA 1PS1A 2J1PA 3VJBA 1N24A 1V4HA 5IVGA 1UBVA 4OMHA 3APZA 3LEEA 3TFPA 1YYRA 5B00A 5E8HA 2ZCOA 3LG5A 5ILIA 3M9UA 5E8KA 3NPKA 3ACXA 3M0GA 4QPFA 5B0IA 2OPNA 4MC8A 5ILHA 3OABA 3KRAB 3NRIA 3QQVA 4OMGA 1UBWA 2PS8A 3B7LA 2Q58A 4KVDA 2E8WA 4KFAA 4JZXA 4P0XA 2E92A 5DGMF 2ZCQA 5IKHA 4N1ZF 4N9UA 3AE0A 3N45F 4LIXA 5DGSF 3N0FA 3PDEA 3SDRA 1N20A 3G4FA 2E93A 2E4OA 4GA3A 3LK5A 3P8LA 4LZCA 1WL3A 3N0GA 2F94F 1V4IA 1YHKA 2P1CA 4LZ0A 3WCBA 3KROA 1YV5A 4KPDA 3EZ3A 4LXWA 3WEKA 4NUAA 3VJCA 4KK2A 5DW7A 4RXEA 4LZ3A 4KWDA 2FORA 3ZOUA 5ERNA 3V66A 3OABB 4F62A 2I19A 1VG3A 3Q2ZA 4JYXA 4DI5A 1VG4A 3Q30A 3WCEA 4LPGF 2E8XA 2AEKA 3ICNA 3RBMA 3VJEA 3WEIA 5A0JA 3KRCA 1N1ZA 3P5RA 1N23A 3CP6A 2Z7IA 5B0LA 5JV0F 1YHLA 3CC9A 4JXNA 4XQSF 4DWBA 3TFVA 3N3DA 2Z4YA 4LUUA 3V1VA 3VJAA 1HXCA 1ZW5A 1EZFA 1YQ7A 2E8UA 2F9KF 3ZMCA 1YYSA 4UMJA 3AQBB 3EFQA 4P0VA 4XQRF 5IL3A 3WC9A 3UCAA 4PVYF 4L2XF 3KRPA 2E8TA 4LA5A 4E9UA 3EGTA 2Z50A 3KROB 2ONHA 1WL1A 5IKAA 3LDWA 3SDUA 4NFIF 4GP1A 2Z7HA 5DHKA 3LGKA 2OGDA 3WCAA 3S9VA
chains in the Genus database with same CATH topology
5B0MA 5JUZF 5A0KA 3G4DA 1WL2A 4NFJF 2E91A 2AZJA 4NG6A 1WL0A 5E8LA 4KVIA 4ZQ8A 4FP4A 4RXCA 4OKZA 2Z4ZA 4GAXA 3WEFA 3AQCB 4FJQA 2VF6A 5DGNF 4LA6A 2AZLA 5AYPA 1RQJA 3QKCA 2O1OA 3KRCB 1HXAA 3N6KF 3NPRA 2F7MF 3MZVA 5DIQF 5EROA 3N1VF 1UBXA 2E95A 1YYQA 4F6VA 4Q23A 2AELA 2PS6A 3PKOA 3ICKA 4H5EF 4OGUA 2F89F 3WSBA 5ILDA 4DWGA 2AZKA 2DH4A 2PS5A 4RXAA 4XQTF 1WMWA 5DJRF 3ZL6A 2FTZA 5IMNA 1YYTA 5C05A 3N49F 3ICZA 3MAVA 5B01A 4JXYA 2Z4WA 3KBKA 5DJPF 3WCDA 4F6XA 3KRPB 3W7FA 3WEHA 2J1OA 5DJVF 4OKMA 5B02A 3RYEA 3Q2QA 2H8OA 5AELA 4MC3A 3N5JF 4WK5A 3SDVA 4EA0A 5I1UA 3DYFA 2Q9YA 5IK9A 2QISA 2PS7A 1WKZA 2E8VA 1JFAA 4NKFA 2ZCRA 1RTRA 5IL8A 3BNYA 5IK6A 1YHMA 4KKMA 3WJKA 5JV1F 4NFKF 3P5PA 4DEMF 3SDTA 3RMGA 4LLSA 4DHDA 3OACA 5A0IA 5DHIA 2E94A 2Q9ZA 3VJDA 4JZBA 3LZ9A 3N1WF 1JFGA 5B03A 1VG2A 5B0JA 4KUXA 2RAHA 3WCJA 3PYBA 3V1XA 4MC0A 3IBAA 4DZWA 2E90A 5EASA 2Q80A 3WJOA 5HN9A 1WY0A 1KIYA 3CKEA 3VJ9A 3KB9A 3DYHA 2PS4A 2F8CF 3M01A 5CG5A 4LLTA 3N46F 3IPIA 3KRFA 5KSXF 2ZCSA 1HM7A 3TC1A 4KQ5A 4LFEA 4HD1A 3LVSA 3WCHA 3NF2A 5IN8A 1KIZA 1DGPA 3WCFA 3ZMBA 3BNXA 3ASXA 4DXJA 1N22A 3PH7A 3P8RA 3TFNA 3WCIA 2ZY1A 3LMDA 4JVJF 1HM4A 4LFVF 4GP2A 5IM1A 2Z4XA 3DYGA 5ILYA 2Z52A 2Z4VA 2OPMA 1VG7A 5AFXA 3LJIA 3ACYA 4LOBA 1YJ4A 4LFGA 2J5CA 3PYAA 3N5HF 5HN8A 3ID0A 3WE9A 3ICMA 4NKEA 3WCCA 3WCGA 3Q1OA 1FPSA 5HNAA 3ACWA 3OACB 4QXSF 1HX9A 3OYRA 5DZ2A 3LSNA 4K10A 4LPHF 4E9ZA 3P41A 3SDQA 1V4KA 4KVWA 1DI1A 5IMIA 3M02A 5H9DA 3VJ8A 4LTZA 2ONGA 5IK0A 3AQ0A 5EATA 5JV2F 4PVXF 1RQIA 4P0WA 3KRAA 5ERMA 1VG6A 3LOMA 5ILKA 4RXDA 4EA2A 1UBYA 3WSAA 2F92F 3ZCDA 3LGZB 3KRFB 3WJNA 3SAEA 3WEJA 4E1EA 4RYPA 4KPJA 4KQSA 5B0KA 4LTVA 2OA6A 1V4EA 3WCLA 2ZEUA 2F8ZF 3WCMA 2AETA 3TS7A 5EAUA 4H5CF 5HN7A 4H5DF 4KVYA 1V4JA 2EWGA 5JA0F 4RNQA 5ILZA 2Z78A 1N1BA 3ADZA 5AHUB 1HXGA 3WEGA 4EA1A 3S4JA 1N21A 5IMPA 3N3LF 3LLWA 5CG6A 3M00A 1YYUA 3RYWA 2ZEVA 5ER8A 4KQUA 5ILJA 1PS1A 2J1PA 3VJBA 1N24A 1V4HA 5IVGA 1UBVA 4OMHA 3APZA 3LEEA 3TFPA 1YYRA 5B00A 5E8HA 2ZCOA 3LG5A 5ILIA 3M9UA 5E8KA 3NPKA 3ACXA 3M0GA 4QPFA 5B0IA 2OPNA 4MC8A 5ILHA 3OABA 3KRAB 3NRIA 3QQVA 4OMGA 1UBWA 2PS8A 3B7LA 2Q58A 4KVDA 2E8WA 4KFAA 4JZXA 4P0XA 2E92A 5DGMF 2ZCQA 5IKHA 4N1ZF 4N9UA 3AE0A 3N45F 4LIXA 5DGSF 3N0FA 3PDEA 3SDRA 1N20A 3G4FA 2E93A 2E4OA 4GA3A 3LK5A 3P8LA 4LZCA 1WL3A 3N0GA 2F94F 1V4IA 1YHKA 2P1CA 4LZ0A 3WCBA 3KROA 1YV5A 4KPDA 3EZ3A 4LXWA 3WEKA 4NUAA 3VJCA 4KK2A 5DW7A 4RXEA 4LZ3A 4KWDA 2FORA 3ZOUA 5ERNA 3V66A 3OABB 4F62A 2I19A 1VG3A 3Q2ZA 4JYXA 4DI5A 1VG4A 3Q30A 3WCEA 4LPGF 2E8XA 2AEKA 3ICNA 3RBMA 3VJEA 3WEIA 5A0JA 3KRCA 1N1ZA 3P5RA 1N23A 3CP6A 2Z7IA 5B0LA 5JV0F 1YHLA 3CC9A 4JXNA 4XQSF 4DWBA 3TFVA 3N3DA 2Z4YA 4LUUA 3V1VA 3VJAA 1HXCA 1ZW5A 1EZFA 1YQ7A 2E8UA 2F9KF 3ZMCA 1YYSA 4UMJA 3AQBB 3EFQA 4P0VA 4XQRF 5IL3A 3WC9A 3UCAA 4PVYF 4L2XF 3KRPA 2E8TA 4LA5A 4E9UA 3EGTA 2Z50A 3KROB 2ONHA 1WL1A 5IKAA 3LDWA 3SDUA 4NFIF 4GP1A 2Z7HA 5DHKA 3LGKA 2OGDA 3WCAA 3S9VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B0M A;  5JUZ F;  5A0K A;  3G4D A;  1WL2 A;  4NFJ F;  2E91 A;  2AZJ A;  4NG6 A;  1WL0 A;  5E8L A;  4KVI A;  4ZQ8 A;  4FP4 A;  4RXC A;  4OKZ A;  2Z4Z A;  4GAX A;  3WEF A;  3AQC B;  4FJQ A;  2VF6 A;  5DGN F;  4LA6 A;  2AZL A;  5AYP A;  1RQJ A;  3QKC A;  2O1O A;  3KRC B;  1HXA A;  3N6K F;  3NPR A;  2F7M F;  3MZV A;  5DIQ F;  5ERO A;  3N1V F;  1UBX A;  2E95 A;  1YYQ A;  4F6V A;  4Q23 A;  2AEL A;  2PS6 A;  3PKO A;  3ICK A;  4H5E F;  4OGU A;  2F89 F;  3WSB A;  5ILD A;  4DWG A;  2AZK A;  2DH4 A;  2PS5 A;  4RXA A;  4XQT F;  1WMW A;  5DJR F;  3ZL6 A;  2FTZ A;  5IMN A;  1YYT A;  5C05 A;  3N49 F;  3ICZ A;  3MAV A;  5B01 A;  4JXY A;  2Z4W A;  3KBK A;  5DJP F;  3WCD A;  4F6X A;  3KRP B;  3W7F A;  3WEH A;  2J1O A;  5DJV F;  4OKM A;  5B02 A;  3RYE A;  3Q2Q A;  2H8O A;  5AEL A;  4MC3 A;  3N5J F;  4WK5 A;  3SDV A;  4EA0 A;  5I1U A;  3DYF A;  2Q9Y A;  5IK9 A;  2QIS A;  2PS7 A;  1WKZ A;  2E8V A;  1JFA A;  4NKF A;  2ZCR A;  1RTR A;  5IL8 A;  3BNY A;  5IK6 A;  1YHM A;  4KKM A;  3WJK A;  5JV1 F;  4NFK F;  3P5P A;  4DEM F;  3SDT A;  3RMG A;  4LLS A;  4DHD A;  3OAC A;  5A0I A;  5DHI A;  2E94 A;  2Q9Z A;  3VJD A;  4JZB A;  3LZ9 A;  3N1W F;  1JFG A;  5B03 A;  1VG2 A;  5B0J A;  4KUX A;  2RAH A;  3WCJ A;  3PYB A;  3V1X A;  4MC0 A;  3IBA A;  4DZW A;  2E90 A;  5EAS A;  2Q80 A;  3WJO A;  5HN9 A;  1WY0 A;  1KIY A;  3CKE A;  3VJ9 A;  3KB9 A;  3DYH A;  2PS4 A;  2F8C F;  3M01 A;  5CG5 A;  4LLT A;  3N46 F;  3IPI A;  3KRF A;  5KSX F;  2ZCS A;  1HM7 A;  3TC1 A;  4KQ5 A;  4LFE A;  4HD1 A;  3LVS A;  3WCH A;  3NF2 A;  5IN8 A;  1KIZ A;  1DGP A;  3WCF A;  3ZMB A;  3BNX A;  3ASX A;  4DXJ A;  1N22 A;  3PH7 A;  3P8R A;  3TFN A;  3WCI A;  2ZY1 A;  3LMD A;  4JVJ F;  1HM4 A;  4LFV F;  4GP2 A;  5IM1 A;  2Z4X A;  3DYG A;  5ILY A;  2Z52 A;  2Z4V A;  2OPM A;  1VG7 A;  5AFX A;  3LJI A;  3ACY A;  4LOB A;  1YJ4 A;  4LFG A;  2J5C A;  3PYA A;  3N5H F;  5HN8 A;  3ID0 A;  3WE9 A;  3ICM A;  4NKE A;  3WCC A;  3WCG A;  3Q1O A;  1FPS A;  5HNA A;  3ACW A;  3OAC B;  4QXS F;  1HX9 A;  3OYR A;  5DZ2 A;  3LSN A;  4K10 A;  4LPH F;  4E9Z A;  3P41 A;  3SDQ A;  1V4K A;  4KVW A;  1DI1 A;  5IMI A;  3M02 A;  5H9D A;  3VJ8 A;  4LTZ A;  2ONG A;  5IK0 A;  3AQ0 A;  5EAT A;  5JV2 F;  4PVX F;  1RQI A;  4P0W A;  3KRA A;  5ERM A;  1VG6 A;  3LOM A;  5ILK A;  4RXD A;  4EA2 A;  1UBY A;  3WSA A;  2F92 F;  3ZCD A;  3LGZ B;  3KRF B;  3WJN A;  3SAE A;  3WEJ A;  4E1E A;  4RYP A;  4KPJ A;  4KQS A;  5B0K A;  4LTV A;  2OA6 A;  1V4E A;  3WCL A;  2ZEU A;  2F8Z F;  3WCM A;  2AET A;  3TS7 A;  5EAU A;  4H5C F;  5HN7 A;  4H5D F;  4KVY A;  1V4J A;  2EWG A;  5JA0 F;  4RNQ A;  5ILZ A;  2Z78 A;  1N1B A;  3ADZ A;  5AHU B;  1HXG A;  3WEG A;  4EA1 A;  3S4J A;  1N21 A;  5IMP A;  3N3L F;  3LLW A;  5CG6 A;  3M00 A;  1YYU A;  3RYW A;  2ZEV A;  5ER8 A;  4KQU A;  5ILJ A;  1PS1 A;  2J1P A;  3VJB A;  1N24 A;  1V4H A;  5IVG A;  1UBV A;  4OMH A;  3APZ A;  3LEE A;  3TFP A;  1YYR A;  5B00 A;  5E8H A;  2ZCO A;  3LG5 A;  5ILI A;  3M9U A;  5E8K A;  3NPK A;  3ACX A;  3M0G A;  4QPF A;  5B0I A;  2OPN A;  4MC8 A;  5ILH A;  3OAB A;  3KRA B;  3NRI A;  3QQV A;  4OMG A;  1UBW A;  2PS8 A;  3B7L A;  2Q58 A;  4KVD A;  2E8W A;  4KFA A;  4JZX A;  4P0X A;  2E92 A;  5DGM F;  2ZCQ A;  5IKH A;  4N1Z F;  4N9U A;  3AE0 A;  3N45 F;  4LIX A;  5DGS F;  3N0F A;  3PDE A;  3SDR A;  1N20 A;  3G4F A;  2E93 A;  2E4O A;  4GA3 A;  3LK5 A;  3P8L A;  4LZC A;  1WL3 A;  3N0G A;  2F94 F;  1V4I A;  1YHK A;  2P1C A;  4LZ0 A;  3WCB A;  3KRO A;  1YV5 A;  4KPD A;  3EZ3 A;  4LXW A;  3WEK A;  4NUA A;  3VJC A;  4KK2 A;  5DW7 A;  4RXE A;  4LZ3 A;  4KWD A;  2FOR A;  3ZOU A;  5ERN A;  3V66 A;  3OAB B;  4F62 A;  2I19 A;  1VG3 A;  3Q2Z A;  4JYX A;  4DI5 A;  1VG4 A;  3Q30 A;  3WCE A;  4LPG F;  2E8X A;  2AEK A;  3ICN A;  3RBM A;  3VJE A;  3WEI A;  5A0J A;  3KRC A;  1N1Z A;  3P5R A;  1N23 A;  3CP6 A;  2Z7I A;  5B0L A;  5JV0 F;  1YHL A;  3CC9 A;  4JXN A;  4XQS F;  4DWB A;  3TFV A;  3N3D A;  2Z4Y A;  4LUU A;  3V1V A;  3VJA A;  1HXC A;  1ZW5 A;  1EZF A;  1YQ7 A;  2E8U A;  2F9K F;  3ZMC A;  1YYS A;  4UMJ A;  3AQB B;  3EFQ A;  4P0V A;  4XQR F;  5IL3 A;  3WC9 A;  3UCA A;  4PVY F;  4L2X F;  3KRP A;  2E8T A;  4LA5 A;  4E9U A;  3EGT A;  2Z50 A;  3KRO B;  2ONH A;  1WL1 A;  5IKA A;  3LDW A;  3SDU A;  4NFI F;  4GP1 A;  2Z7H A;  5DHK A;  3LGK A;  2OGD A;  3WCA A;  3S9V A; 
#chains in the Genus database with same CATH topology
 5B0M A;  5JUZ F;  5A0K A;  3G4D A;  1WL2 A;  4NFJ F;  2E91 A;  2AZJ A;  4NG6 A;  1WL0 A;  5E8L A;  4KVI A;  4ZQ8 A;  4FP4 A;  4RXC A;  4OKZ A;  2Z4Z A;  4GAX A;  3WEF A;  3AQC B;  4FJQ A;  2VF6 A;  5DGN F;  4LA6 A;  2AZL A;  5AYP A;  1RQJ A;  3QKC A;  2O1O A;  3KRC B;  1HXA A;  3N6K F;  3NPR A;  2F7M F;  3MZV A;  5DIQ F;  5ERO A;  3N1V F;  1UBX A;  2E95 A;  1YYQ A;  4F6V A;  4Q23 A;  2AEL A;  2PS6 A;  3PKO A;  3ICK A;  4H5E F;  4OGU A;  2F89 F;  3WSB A;  5ILD A;  4DWG A;  2AZK A;  2DH4 A;  2PS5 A;  4RXA A;  4XQT F;  1WMW A;  5DJR F;  3ZL6 A;  2FTZ A;  5IMN A;  1YYT A;  5C05 A;  3N49 F;  3ICZ A;  3MAV A;  5B01 A;  4JXY A;  2Z4W A;  3KBK A;  5DJP F;  3WCD A;  4F6X A;  3KRP B;  3W7F A;  3WEH A;  2J1O A;  5DJV F;  4OKM A;  5B02 A;  3RYE A;  3Q2Q A;  2H8O A;  5AEL A;  4MC3 A;  3N5J F;  4WK5 A;  3SDV A;  4EA0 A;  5I1U A;  3DYF A;  2Q9Y A;  5IK9 A;  2QIS A;  2PS7 A;  1WKZ A;  2E8V A;  1JFA A;  4NKF A;  2ZCR A;  1RTR A;  5IL8 A;  3BNY A;  5IK6 A;  1YHM A;  4KKM A;  3WJK A;  5JV1 F;  4NFK F;  3P5P A;  4DEM F;  3SDT A;  3RMG A;  4LLS A;  4DHD A;  3OAC A;  5A0I A;  5DHI A;  2E94 A;  2Q9Z A;  3VJD A;  4JZB A;  3LZ9 A;  3N1W F;  1JFG A;  5B03 A;  1VG2 A;  5B0J A;  4KUX A;  2RAH A;  3WCJ A;  3PYB A;  3V1X A;  4MC0 A;  3IBA A;  4DZW A;  2E90 A;  5EAS A;  2Q80 A;  3WJO A;  5HN9 A;  1WY0 A;  1KIY A;  3CKE A;  3VJ9 A;  3KB9 A;  3DYH A;  2PS4 A;  2F8C F;  3M01 A;  5CG5 A;  4LLT A;  3N46 F;  3IPI A;  3KRF A;  5KSX F;  2ZCS A;  1HM7 A;  3TC1 A;  4KQ5 A;  4LFE A;  4HD1 A;  3LVS A;  3WCH A;  3NF2 A;  5IN8 A;  1KIZ A;  1DGP A;  3WCF A;  3ZMB A;  3BNX A;  3ASX A;  4DXJ A;  1N22 A;  3PH7 A;  3P8R A;  3TFN A;  3WCI A;  2ZY1 A;  3LMD A;  4JVJ F;  1HM4 A;  4LFV F;  4GP2 A;  5IM1 A;  2Z4X A;  3DYG A;  5ILY A;  2Z52 A;  2Z4V A;  2OPM A;  1VG7 A;  5AFX A;  3LJI A;  3ACY A;  4LOB A;  1YJ4 A;  4LFG A;  2J5C A;  3PYA A;  3N5H F;  5HN8 A;  3ID0 A;  3WE9 A;  3ICM A;  4NKE A;  3WCC A;  3WCG A;  3Q1O A;  1FPS A;  5HNA A;  3ACW A;  3OAC B;  4QXS F;  1HX9 A;  3OYR A;  5DZ2 A;  3LSN A;  4K10 A;  4LPH F;  4E9Z A;  3P41 A;  3SDQ A;  1V4K A;  4KVW A;  1DI1 A;  5IMI A;  3M02 A;  5H9D A;  3VJ8 A;  4LTZ A;  2ONG A;  5IK0 A;  3AQ0 A;  5EAT A;  5JV2 F;  4PVX F;  1RQI A;  4P0W A;  3KRA A;  5ERM A;  1VG6 A;  3LOM A;  5ILK A;  4RXD A;  4EA2 A;  1UBY A;  3WSA A;  2F92 F;  3ZCD A;  3LGZ B;  3KRF B;  3WJN A;  3SAE A;  3WEJ A;  4E1E A;  4RYP A;  4KPJ A;  4KQS A;  5B0K A;  4LTV A;  2OA6 A;  1V4E A;  3WCL A;  2ZEU A;  2F8Z F;  3WCM A;  2AET A;  3TS7 A;  5EAU A;  4H5C F;  5HN7 A;  4H5D F;  4KVY A;  1V4J A;  2EWG A;  5JA0 F;  4RNQ A;  5ILZ A;  2Z78 A;  1N1B A;  3ADZ A;  5AHU B;  1HXG A;  3WEG A;  4EA1 A;  3S4J A;  1N21 A;  5IMP A;  3N3L F;  3LLW A;  5CG6 A;  3M00 A;  1YYU A;  3RYW A;  2ZEV A;  5ER8 A;  4KQU A;  5ILJ A;  1PS1 A;  2J1P A;  3VJB A;  1N24 A;  1V4H A;  5IVG A;  1UBV A;  4OMH A;  3APZ A;  3LEE A;  3TFP A;  1YYR A;  5B00 A;  5E8H A;  2ZCO A;  3LG5 A;  5ILI A;  3M9U A;  5E8K A;  3NPK A;  3ACX A;  3M0G A;  4QPF A;  5B0I A;  2OPN A;  4MC8 A;  5ILH A;  3OAB A;  3KRA B;  3NRI A;  3QQV A;  4OMG A;  1UBW A;  2PS8 A;  3B7L A;  2Q58 A;  4KVD A;  2E8W A;  4KFA A;  4JZX A;  4P0X A;  2E92 A;  5DGM F;  2ZCQ A;  5IKH A;  4N1Z F;  4N9U A;  3AE0 A;  3N45 F;  4LIX A;  5DGS F;  3N0F A;  3PDE A;  3SDR A;  1N20 A;  3G4F A;  2E93 A;  2E4O A;  4GA3 A;  3LK5 A;  3P8L A;  4LZC A;  1WL3 A;  3N0G A;  2F94 F;  1V4I A;  1YHK A;  2P1C A;  4LZ0 A;  3WCB A;  3KRO A;  1YV5 A;  4KPD A;  3EZ3 A;  4LXW A;  3WEK A;  4NUA A;  3VJC A;  4KK2 A;  5DW7 A;  4RXE A;  4LZ3 A;  4KWD A;  2FOR A;  3ZOU A;  5ERN A;  3V66 A;  3OAB B;  4F62 A;  2I19 A;  1VG3 A;  3Q2Z A;  4JYX A;  4DI5 A;  1VG4 A;  3Q30 A;  3WCE A;  4LPG F;  2E8X A;  2AEK A;  3ICN A;  3RBM A;  3VJE A;  3WEI A;  5A0J A;  3KRC A;  1N1Z A;  3P5R A;  1N23 A;  3CP6 A;  2Z7I A;  5B0L A;  5JV0 F;  1YHL A;  3CC9 A;  4JXN A;  4XQS F;  4DWB A;  3TFV A;  3N3D A;  2Z4Y A;  4LUU A;  3V1V A;  3VJA A;  1HXC A;  1ZW5 A;  1EZF A;  1YQ7 A;  2E8U A;  2F9K F;  3ZMC A;  1YYS A;  4UMJ A;  3AQB B;  3EFQ A;  4P0V A;  4XQR F;  5IL3 A;  3WC9 A;  3UCA A;  4PVY F;  4L2X F;  3KRP A;  2E8T A;  4LA5 A;  4E9U A;  3EGT A;  2Z50 A;  3KRO B;  2ONH A;  1WL1 A;  5IKA A;  3LDW A;  3SDU A;  4NFI F;  4GP1 A;  2Z7H A;  5DHK A;  3LGK A;  2OGD A;  3WCA A;  3S9V A; 
#chains in the Genus database with same CATH homology
 5B0M A;  5JUZ F;  5A0K A;  3G4D A;  1WL2 A;  4NFJ F;  2E91 A;  2AZJ A;  4NG6 A;  1WL0 A;  5E8L A;  4KVI A;  4ZQ8 A;  4FP4 A;  4RXC A;  4OKZ A;  2Z4Z A;  4GAX A;  3WEF A;  3AQC B;  4FJQ A;  2VF6 A;  5DGN F;  4LA6 A;  2AZL A;  5AYP A;  1RQJ A;  3QKC A;  2O1O A;  3KRC B;  1HXA A;  3N6K F;  3NPR A;  2F7M F;  3MZV A;  5DIQ F;  5ERO A;  3N1V F;  1UBX A;  2E95 A;  1YYQ A;  4F6V A;  4Q23 A;  2AEL A;  2PS6 A;  3PKO A;  3ICK A;  4H5E F;  4OGU A;  2F89 F;  3WSB A;  5ILD A;  4DWG A;  2AZK A;  2DH4 A;  2PS5 A;  4RXA A;  4XQT F;  1WMW A;  5DJR F;  3ZL6 A;  2FTZ A;  5IMN A;  1YYT A;  5C05 A;  3N49 F;  3ICZ A;  3MAV A;  5B01 A;  4JXY A;  2Z4W A;  3KBK A;  5DJP F;  3WCD A;  4F6X A;  3KRP B;  3W7F A;  3WEH A;  2J1O A;  5DJV F;  4OKM A;  5B02 A;  3RYE A;  3Q2Q A;  2H8O A;  5AEL A;  4MC3 A;  3N5J F;  4WK5 A;  3SDV A;  4EA0 A;  5I1U A;  3DYF A;  2Q9Y A;  5IK9 A;  2QIS A;  2PS7 A;  1WKZ A;  2E8V A;  1JFA A;  4NKF A;  2ZCR A;  1RTR A;  5IL8 A;  3BNY A;  5IK6 A;  1YHM A;  4KKM A;  3WJK A;  5JV1 F;  4NFK F;  3P5P A;  4DEM F;  3SDT A;  3RMG A;  4LLS A;  4DHD A;  3OAC A;  5A0I A;  5DHI A;  2E94 A;  2Q9Z A;  3VJD A;  4JZB A;  3LZ9 A;  3N1W F;  1JFG A;  5B03 A;  1VG2 A;  5B0J A;  4KUX A;  2RAH A;  3WCJ A;  3PYB A;  3V1X A;  4MC0 A;  3IBA A;  4DZW A;  2E90 A;  5EAS A;  2Q80 A;  3WJO A;  5HN9 A;  1WY0 A;  1KIY A;  3CKE A;  3VJ9 A;  3KB9 A;  3DYH A;  2PS4 A;  2F8C F;  3M01 A;  5CG5 A;  4LLT A;  3N46 F;  3IPI A;  3KRF A;  5KSX F;  2ZCS A;  1HM7 A;  3TC1 A;  4KQ5 A;  4LFE A;  4HD1 A;  3LVS A;  3WCH A;  3NF2 A;  5IN8 A;  1KIZ A;  1DGP A;  3WCF A;  3ZMB A;  3BNX A;  3ASX A;  4DXJ A;  1N22 A;  3PH7 A;  3P8R A;  3TFN A;  3WCI A;  2ZY1 A;  3LMD A;  4JVJ F;  1HM4 A;  4LFV F;  4GP2 A;  5IM1 A;  2Z4X A;  3DYG A;  5ILY A;  2Z52 A;  2Z4V A;  2OPM A;  1VG7 A;  5AFX A;  3LJI A;  3ACY A;  4LOB A;  1YJ4 A;  4LFG A;  2J5C A;  3PYA A;  3N5H F;  5HN8 A;  3ID0 A;  3WE9 A;  3ICM A;  4NKE A;  3WCC A;  3WCG A;  3Q1O A;  1FPS A;  5HNA A;  3ACW A;  3OAC B;  4QXS F;  1HX9 A;  3OYR A;  5DZ2 A;  3LSN A;  4K10 A;  4LPH F;  4E9Z A;  3P41 A;  3SDQ A;  1V4K A;  4KVW A;  1DI1 A;  5IMI A;  3M02 A;  5H9D A;  3VJ8 A;  4LTZ A;  2ONG A;  5IK0 A;  3AQ0 A;  5EAT A;  5JV2 F;  4PVX F;  1RQI A;  4P0W A;  3KRA A;  5ERM A;  1VG6 A;  3LOM A;  5ILK A;  4RXD A;  4EA2 A;  1UBY A;  3WSA A;  2F92 F;  3ZCD A;  3LGZ B;  3KRF B;  3WJN A;  3SAE A;  3WEJ A;  4E1E A;  4RYP A;  4KPJ A;  4KQS A;  5B0K A;  4LTV A;  2OA6 A;  1V4E A;  3WCL A;  2ZEU A;  2F8Z F;  3WCM A;  2AET A;  3TS7 A;  5EAU A;  4H5C F;  5HN7 A;  4H5D F;  4KVY A;  1V4J A;  2EWG A;  5JA0 F;  4RNQ A;  5ILZ A;  2Z78 A;  1N1B A;  3ADZ A;  5AHU B;  1HXG A;  3WEG A;  4EA1 A;  3S4J A;  1N21 A;  5IMP A;  3N3L F;  3LLW A;  5CG6 A;  3M00 A;  1YYU A;  3RYW A;  2ZEV A;  5ER8 A;  4KQU A;  5ILJ A;  1PS1 A;  2J1P A;  3VJB A;  1N24 A;  1V4H A;  5IVG A;  1UBV A;  4OMH A;  3APZ A;  3LEE A;  3TFP A;  1YYR A;  5B00 A;  5E8H A;  2ZCO A;  3LG5 A;  5ILI A;  3M9U A;  5E8K A;  3NPK A;  3ACX A;  3M0G A;  4QPF A;  5B0I A;  2OPN A;  4MC8 A;  5ILH A;  3OAB A;  3KRA B;  3NRI A;  3QQV A;  4OMG A;  1UBW A;  2PS8 A;  3B7L A;  2Q58 A;  4KVD A;  2E8W A;  4KFA A;  4JZX A;  4P0X A;  2E92 A;  5DGM F;  2ZCQ A;  5IKH A;  4N1Z F;  4N9U A;  3AE0 A;  3N45 F;  4LIX A;  5DGS F;  3N0F A;  3PDE A;  3SDR A;  1N20 A;  3G4F A;  2E93 A;  2E4O A;  4GA3 A;  3LK5 A;  3P8L A;  4LZC A;  1WL3 A;  3N0G A;  2F94 F;  1V4I A;  1YHK A;  2P1C A;  4LZ0 A;  3WCB A;  3KRO A;  1YV5 A;  4KPD A;  3EZ3 A;  4LXW A;  3WEK A;  4NUA A;  3VJC A;  4KK2 A;  5DW7 A;  4RXE A;  4LZ3 A;  4KWD A;  2FOR A;  3ZOU A;  5ERN A;  3V66 A;  3OAB B;  4F62 A;  2I19 A;  1VG3 A;  3Q2Z A;  4JYX A;  4DI5 A;  1VG4 A;  3Q30 A;  3WCE A;  4LPG F;  2E8X A;  2AEK A;  3ICN A;  3RBM A;  3VJE A;  3WEI A;  5A0J A;  3KRC A;  1N1Z A;  3P5R A;  1N23 A;  3CP6 A;  2Z7I A;  5B0L A;  5JV0 F;  1YHL A;  3CC9 A;  4JXN A;  4XQS F;  4DWB A;  3TFV A;  3N3D A;  2Z4Y A;  4LUU A;  3V1V A;  3VJA A;  1HXC A;  1ZW5 A;  1EZF A;  1YQ7 A;  2E8U A;  2F9K F;  3ZMC A;  1YYS A;  4UMJ A;  3AQB B;  3EFQ A;  4P0V A;  4XQR F;  5IL3 A;  3WC9 A;  3UCA A;  4PVY F;  4L2X F;  3KRP A;  2E8T A;  4LA5 A;  4E9U A;  3EGT A;  2Z50 A;  3KRO B;  2ONH A;  1WL1 A;  5IKA A;  3LDW A;  3SDU A;  4NFI F;  4GP1 A;  2Z7H A;  5DHK A;  3LGK A;  2OGD A;  3WCA A;  3S9V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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