4DWGA

Crystal structure of trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 150
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
150
sequence length
361
structure length
361
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 150
structure length 361
sequence length 361
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dwgA00
1WKZA 3KRCB 4GP2A 3Q2QA 4LA6A 2E91A 2P1CA 4MC8A 3N5HF 3OYRA 4XQTF 5EAUA 5HN9A 2E94A 3AQCB 4L2XF 3VJ9A 3ACXA 3WEIA 4RXDA 1VG4A 2Z4WA 3MZVA 4HD1A 4LUUA 4XQRF 3ZCDA 4DWBA 3RBMA 3N5JF 1N1BA 4LLTA 5C05A 5B0MA 5ILDA 5CG5A 2O1OA 4KVDA 5ILJA 4RXEA 2E8TA 1YHMA 3LLWA 5IL8A 1YYTA 5ILHA 3Q2ZA 4NKFA 2E8UA 3AE0A 1YYSA 3LJIA 3TFNA 4JXYA 4LTVA 5B03A 2DH4A 1WL2A 3OACB 4KK2A 3S4JA 4PVXF 3KBKA 4KVIA 5HN8A 1HXAA 3N49F 3G4DA 2AELA 3WJNA 3TFPA 1EZFA 3OABB 3Q1OA 1V4JA 4NUAA 5HNAA 3SDVA 5DHIA 1YV5A 2F92F 5I1UA 2ZEUA 1RTRA 2Q9ZA 3N6KF 5IKHA 4OKZA 4OGUA 2Z7IA 4GAXA 3QQVA 1HM7A 5JUZF 5ILKA 4N1ZF 2E8WA 1UBWA 3WEGA 1HXGA 5IMPA 5AHUB 5IMIA 3KROB 3LEEA 3M00A 2Q9YA 3WC9A 3W7FA 4JVJF 3N1WF 3LVSA 2PS6A 5DJRF 2ZEVA 3SAEA 3V66A 1UBYA 2AZLA 3P8RA 4LIXA 5E8KA 2F8CF 5IM1A 5A0JA 5DGMF 1KIYA 3N1VF 3LG5A 3PDEA 3DYHA 4KQUA 1V4HA 2ZCQA 2OGDA 1RQJA 3Q30A 2PS8A 2AEKA 4PVYF 4KQ5A 3LOMA 4DI5A 3G4FA 5DW7A 2ZY1A 3WCHA 2FTZA 4LLSA 4RNQA 3WEJA 3WCFA 4KQSA 5B0JA 5B00A 4K10A 3VJCA 1YYQA 3BNXA 4NG6A 3V1XA 4NFKF 1V4EA 3WJKA 5CG6A 3WCDA 3NF2A 3APZA 3ASXA 4DWGA 3EZ3A 4Q23A 2J5CA 3DYGA 3PH7A 3PYBA 4EA2A 1N1ZA 4KVWA 5A0KA 2F9KF 1N22A 3ZMCA 3TC1A 3KB9A 1ZW5A 4JXNA 1N23A 4LZCA 1VG7A 4NFJF 4KFAA 4KKMA 3WE9A 5IVGA 2PS4A 2Q58A 1HXCA 2J1PA 4LTZA 4KPJA 3SDTA 5IK6A 1DGPA 3N0FA 1WL0A 5DGNF 4LA5A 1KIZA 3WCEA 3KRFA 1VG6A 2J1OA 4EA0A 2E8VA 5AFXA 5DZ2A 4EA1A 4KPDA 3QKCA 1FPSA 3SDUA 4OKMA 2AZKA 3NPRA 5H9DA 5B0KA 5JV0F 3M0GA 5IK9A 5JV2F 3NPKA 3PKOA 3KRPA 4P0VA 4E9ZA 3IBAA 3EGTA 5E8HA 3B7LA 3N3DA 3RYWA 2ONGA 5IK0A 3N46F 2E95A 3NRIA 2ZCSA 1UBXA 2F7MF 5IKAA 5B02A 3ZL6A 2OPNA 5EROA 3M02A 3LMDA 2E4OA 3LZ9A 3RYEA 5IL3A 3WCIA 4JZXA 1HM4A 3KRAA 3WCJA 4RYPA 4UMJA 4LXWA 5JV1F 3ADZA 1WL1A 1YJ4A 4NKEA 3KRCA 3EFQA 1WY0A 1JFAA 3WEHA 1YYUA 5B0LA 5DGSF 2AZJA 3LK5A 2RAHA 3SDRA 5E8LA 3M9UA 3LGZB 5ILZA 3ICNA 4LZ0A 5ILYA 3ZMBA 3WCLA 3P8LA 4XQSF 2F8ZF 3LDWA 1V4IA 4F6XA 2ZCRA 4FP4A 5HN7A 2Z7HA 3P5PA 3PYAA 2Z4XA 2H8OA 3N3LF 3P41A 4H5DF 5ER8A 3DYFA 3WSAA 5B01A 1VG3A 4P0XA 1WL3A 4NFIF 3VJDA 3N45F 3CP6A 3M01A 5AYPA 2Z78A 4KVYA 1N20A 2QISA 3OACA 3VJBA 2AETA 1YYRA 5ILIA 2ONHA 2Z50A 3OABA 4QPFA 4F6VA 1YHKA 3UCAA 3VJAA 3WEFA 3ACWA 1V4KA 3SDQA 1UBVA 4DEMF 2OA6A 3WCGA 1YQ7A 4OMGA 5DJPF 2PS5A 4LZ3A 4ZQ8A 5DHKA 5IMNA 3KROA 3ICKA 3ICZA 3WEKA 4E9UA 1N21A 3V1VA 2E90A 2F89F 2EWGA 2E93A 4LOBA 3RMGA 2ZCOA 5EATA 3N0GA 1RQIA 1HX9A 4N9UA 3ID0A 4LPHF 4MC0A 2Z4ZA 4H5EF 3WCAA 4KWDA 5ERNA 3LGKA 2F94F 4WK5A 4OMHA 4RXAA 5IN8A 1WMWA 3MAVA 1DI1A 4F62A 4MC3A 2OPMA 3WSBA 3AQ0A 4DHDA 3S9VA 1VG2A 5DIQF 3TFVA 3WCBA 2I19A 4JZBA 3KRFB 3P5RA 4QXSF 3ICMA 5AELA 5DJVF 1N24A 4LFEA 3WCCA 3IPIA 4RXCA 4P0WA 4LPGF 1YHLA 5JA0F 4LFVF 5EASA 3KRPB 2Z4VA 5ERMA 3BNYA 5KSXF 2Q80A 2E92A 3AQBB 4FJQA 3CKEA 4GA3A 1JFGA 3LSNA 2VF6A 4LFGA 3ACYA 4KUXA 3ZOUA 3CC9A 4DXJA 4GP1A 3VJ8A 2Z4YA 3WCMA 1PS1A 5B0IA 2E8XA 4H5CF 2Z52A 2FORA 3TS7A 5A0IA 4JYXA 3KRAB 4E1EA 3WJOA 3VJEA 2PS7A 4DZWA
chains in the Genus database with same CATH superfamily
1WKZA 3KRCB 4GP2A 3Q2QA 4LA6A 2E91A 2P1CA 4MC8A 3N5HF 3OYRA 4XQTF 5EAUA 5HN9A 2E94A 3AQCB 4L2XF 3VJ9A 3ACXA 3WEIA 4RXDA 1VG4A 2Z4WA 3MZVA 4HD1A 4LUUA 4XQRF 3ZCDA 4DWBA 3RBMA 3N5JF 1N1BA 4LLTA 5C05A 5B0MA 5ILDA 5CG5A 2O1OA 4KVDA 5ILJA 4RXEA 2E8TA 1YHMA 3LLWA 5IL8A 1YYTA 5ILHA 3Q2ZA 4NKFA 2E8UA 3AE0A 1YYSA 3LJIA 3TFNA 4JXYA 4LTVA 5B03A 2DH4A 1WL2A 3OACB 4KK2A 3S4JA 4PVXF 3KBKA 4KVIA 5HN8A 1HXAA 3N49F 3G4DA 2AELA 3WJNA 3TFPA 1EZFA 3OABB 3Q1OA 1V4JA 4NUAA 5HNAA 3SDVA 5DHIA 1YV5A 2F92F 5I1UA 2ZEUA 1RTRA 2Q9ZA 3N6KF 5IKHA 4OKZA 4OGUA 2Z7IA 4GAXA 3QQVA 1HM7A 5JUZF 5ILKA 4N1ZF 2E8WA 1UBWA 3WEGA 1HXGA 5IMPA 5AHUB 5IMIA 3KROB 3LEEA 3M00A 2Q9YA 3WC9A 3W7FA 4JVJF 3N1WF 3LVSA 2PS6A 5DJRF 2ZEVA 3SAEA 3V66A 1UBYA 2AZLA 3P8RA 4LIXA 5E8KA 2F8CF 5IM1A 5A0JA 5DGMF 1KIYA 3N1VF 3LG5A 3PDEA 3DYHA 4KQUA 1V4HA 2ZCQA 2OGDA 1RQJA 3Q30A 2PS8A 2AEKA 4PVYF 4KQ5A 3LOMA 4DI5A 3G4FA 5DW7A 2ZY1A 3WCHA 2FTZA 4LLSA 4RNQA 3WEJA 3WCFA 4KQSA 5B0JA 5B00A 4K10A 3VJCA 1YYQA 3BNXA 4NG6A 3V1XA 4NFKF 1V4EA 3WJKA 5CG6A 3WCDA 3NF2A 3APZA 3ASXA 4DWGA 3EZ3A 4Q23A 2J5CA 3DYGA 3PH7A 3PYBA 4EA2A 1N1ZA 4KVWA 5A0KA 2F9KF 1N22A 3ZMCA 3TC1A 3KB9A 1ZW5A 4JXNA 1N23A 4LZCA 1VG7A 4NFJF 4KFAA 4KKMA 3WE9A 5IVGA 2PS4A 2Q58A 1HXCA 2J1PA 4LTZA 4KPJA 3SDTA 5IK6A 1DGPA 3N0FA 1WL0A 5DGNF 4LA5A 1KIZA 3WCEA 3KRFA 1VG6A 2J1OA 4EA0A 2E8VA 5AFXA 5DZ2A 4EA1A 4KPDA 3QKCA 1FPSA 3SDUA 4OKMA 2AZKA 3NPRA 5H9DA 5B0KA 5JV0F 3M0GA 5IK9A 5JV2F 3NPKA 3PKOA 3KRPA 4P0VA 4E9ZA 3IBAA 3EGTA 5E8HA 3B7LA 3N3DA 3RYWA 2ONGA 5IK0A 3N46F 2E95A 3NRIA 2ZCSA 1UBXA 2F7MF 5IKAA 5B02A 3ZL6A 2OPNA 5EROA 3M02A 3LMDA 2E4OA 3LZ9A 3RYEA 5IL3A 3WCIA 4JZXA 1HM4A 3KRAA 3WCJA 4RYPA 4UMJA 4LXWA 5JV1F 3ADZA 1WL1A 1YJ4A 4NKEA 3KRCA 3EFQA 1WY0A 1JFAA 3WEHA 1YYUA 5B0LA 5DGSF 2AZJA 3LK5A 2RAHA 3SDRA 5E8LA 3M9UA 3LGZB 5ILZA 3ICNA 4LZ0A 5ILYA 3ZMBA 3WCLA 3P8LA 4XQSF 2F8ZF 3LDWA 1V4IA 4F6XA 2ZCRA 4FP4A 5HN7A 2Z7HA 3P5PA 3PYAA 2Z4XA 2H8OA 3N3LF 3P41A 4H5DF 5ER8A 3DYFA 3WSAA 5B01A 1VG3A 4P0XA 1WL3A 4NFIF 3VJDA 3N45F 3CP6A 3M01A 5AYPA 2Z78A 4KVYA 1N20A 2QISA 3OACA 3VJBA 2AETA 1YYRA 5ILIA 2ONHA 2Z50A 3OABA 4QPFA 4F6VA 1YHKA 3UCAA 3VJAA 3WEFA 3ACWA 1V4KA 3SDQA 1UBVA 4DEMF 2OA6A 3WCGA 1YQ7A 4OMGA 5DJPF 2PS5A 4LZ3A 4ZQ8A 5DHKA 5IMNA 3KROA 3ICKA 3ICZA 3WEKA 4E9UA 1N21A 3V1VA 2E90A 2F89F 2EWGA 2E93A 4LOBA 3RMGA 2ZCOA 5EATA 3N0GA 1RQIA 1HX9A 4N9UA 3ID0A 4LPHF 4MC0A 2Z4ZA 4H5EF 3WCAA 4KWDA 5ERNA 3LGKA 2F94F 4WK5A 4OMHA 4RXAA 5IN8A 1WMWA 3MAVA 1DI1A 4F62A 4MC3A 2OPMA 3WSBA 3AQ0A 4DHDA 3S9VA 1VG2A 5DIQF 3TFVA 3WCBA 2I19A 4JZBA 3KRFB 3P5RA 4QXSF 3ICMA 5AELA 5DJVF 1N24A 4LFEA 3WCCA 3IPIA 4RXCA 4P0WA 4LPGF 1YHLA 5JA0F 4LFVF 5EASA 3KRPB 2Z4VA 5ERMA 3BNYA 5KSXF 2Q80A 2E92A 3AQBB 4FJQA 3CKEA 4GA3A 1JFGA 3LSNA 2VF6A 4LFGA 3ACYA 4KUXA 3ZOUA 3CC9A 4DXJA 4GP1A 3VJ8A 2Z4YA 3WCMA 1PS1A 5B0IA 2E8XA 4H5CF 2Z52A 2FORA 3TS7A 5A0IA 4JYXA 3KRAB 4E1EA 3WJOA 3VJEA 2PS7A 4DZWA
chains in the Genus database with same CATH topology
1WKZA 3KRCB 4GP2A 3Q2QA 4LA6A 2E91A 2P1CA 4MC8A 3N5HF 3OYRA 4XQTF 5EAUA 5HN9A 2E94A 3AQCB 4L2XF 3VJ9A 3ACXA 3WEIA 4RXDA 1VG4A 2Z4WA 3MZVA 4HD1A 4LUUA 4XQRF 3ZCDA 4DWBA 3RBMA 3N5JF 1N1BA 4LLTA 5C05A 5B0MA 5ILDA 5CG5A 2O1OA 4KVDA 5ILJA 4RXEA 2E8TA 1YHMA 3LLWA 5IL8A 1YYTA 5ILHA 3Q2ZA 4NKFA 2E8UA 3AE0A 1YYSA 3LJIA 3TFNA 4JXYA 4LTVA 5B03A 2DH4A 1WL2A 3OACB 4KK2A 3S4JA 4PVXF 3KBKA 4KVIA 5HN8A 1HXAA 3N49F 3G4DA 2AELA 3WJNA 3TFPA 1EZFA 3OABB 3Q1OA 1V4JA 4NUAA 5HNAA 3SDVA 5DHIA 1YV5A 2F92F 5I1UA 2ZEUA 1RTRA 2Q9ZA 3N6KF 5IKHA 4OKZA 4OGUA 2Z7IA 4GAXA 3QQVA 1HM7A 5JUZF 5ILKA 4N1ZF 2E8WA 1UBWA 3WEGA 1HXGA 5IMPA 5AHUB 5IMIA 3KROB 3LEEA 3M00A 2Q9YA 3WC9A 3W7FA 4JVJF 3N1WF 3LVSA 2PS6A 5DJRF 2ZEVA 3SAEA 3V66A 1UBYA 2AZLA 3P8RA 4LIXA 5E8KA 2F8CF 5IM1A 5A0JA 5DGMF 1KIYA 3N1VF 3LG5A 3PDEA 3DYHA 4KQUA 1V4HA 2ZCQA 2OGDA 1RQJA 3Q30A 2PS8A 2AEKA 4PVYF 4KQ5A 3LOMA 4DI5A 3G4FA 5DW7A 2ZY1A 3WCHA 2FTZA 4LLSA 4RNQA 3WEJA 3WCFA 4KQSA 5B0JA 5B00A 4K10A 3VJCA 1YYQA 3BNXA 4NG6A 3V1XA 4NFKF 1V4EA 3WJKA 5CG6A 3WCDA 3NF2A 3APZA 3ASXA 4DWGA 3EZ3A 4Q23A 2J5CA 3DYGA 3PH7A 3PYBA 4EA2A 1N1ZA 4KVWA 5A0KA 2F9KF 1N22A 3ZMCA 3TC1A 3KB9A 1ZW5A 4JXNA 1N23A 4LZCA 1VG7A 4NFJF 4KFAA 4KKMA 3WE9A 5IVGA 2PS4A 2Q58A 1HXCA 2J1PA 4LTZA 4KPJA 3SDTA 5IK6A 1DGPA 3N0FA 1WL0A 5DGNF 4LA5A 1KIZA 3WCEA 3KRFA 1VG6A 2J1OA 4EA0A 2E8VA 5AFXA 5DZ2A 4EA1A 4KPDA 3QKCA 1FPSA 3SDUA 4OKMA 2AZKA 3NPRA 5H9DA 5B0KA 5JV0F 3M0GA 5IK9A 5JV2F 3NPKA 3PKOA 3KRPA 4P0VA 4E9ZA 3IBAA 3EGTA 5E8HA 3B7LA 3N3DA 3RYWA 2ONGA 5IK0A 3N46F 2E95A 3NRIA 2ZCSA 1UBXA 2F7MF 5IKAA 5B02A 3ZL6A 2OPNA 5EROA 3M02A 3LMDA 2E4OA 3LZ9A 3RYEA 5IL3A 3WCIA 4JZXA 1HM4A 3KRAA 3WCJA 4RYPA 4UMJA 4LXWA 5JV1F 3ADZA 1WL1A 1YJ4A 4NKEA 3KRCA 3EFQA 1WY0A 1JFAA 3WEHA 1YYUA 5B0LA 5DGSF 2AZJA 3LK5A 2RAHA 3SDRA 5E8LA 3M9UA 3LGZB 5ILZA 3ICNA 4LZ0A 5ILYA 3ZMBA 3WCLA 3P8LA 4XQSF 2F8ZF 3LDWA 1V4IA 4F6XA 2ZCRA 4FP4A 5HN7A 2Z7HA 3P5PA 3PYAA 2Z4XA 2H8OA 3N3LF 3P41A 4H5DF 5ER8A 3DYFA 3WSAA 5B01A 1VG3A 4P0XA 1WL3A 4NFIF 3VJDA 3N45F 3CP6A 3M01A 5AYPA 2Z78A 4KVYA 1N20A 2QISA 3OACA 3VJBA 2AETA 1YYRA 5ILIA 2ONHA 2Z50A 3OABA 4QPFA 4F6VA 1YHKA 3UCAA 3VJAA 3WEFA 3ACWA 1V4KA 3SDQA 1UBVA 4DEMF 2OA6A 3WCGA 1YQ7A 4OMGA 5DJPF 2PS5A 4LZ3A 4ZQ8A 5DHKA 5IMNA 3KROA 3ICKA 3ICZA 3WEKA 4E9UA 1N21A 3V1VA 2E90A 2F89F 2EWGA 2E93A 4LOBA 3RMGA 2ZCOA 5EATA 3N0GA 1RQIA 1HX9A 4N9UA 3ID0A 4LPHF 4MC0A 2Z4ZA 4H5EF 3WCAA 4KWDA 5ERNA 3LGKA 2F94F 4WK5A 4OMHA 4RXAA 5IN8A 1WMWA 3MAVA 1DI1A 4F62A 4MC3A 2OPMA 3WSBA 3AQ0A 4DHDA 3S9VA 1VG2A 5DIQF 3TFVA 3WCBA 2I19A 4JZBA 3KRFB 3P5RA 4QXSF 3ICMA 5AELA 5DJVF 1N24A 4LFEA 3WCCA 3IPIA 4RXCA 4P0WA 4LPGF 1YHLA 5JA0F 4LFVF 5EASA 3KRPB 2Z4VA 5ERMA 3BNYA 5KSXF 2Q80A 2E92A 3AQBB 4FJQA 3CKEA 4GA3A 1JFGA 3LSNA 2VF6A 4LFGA 3ACYA 4KUXA 3ZOUA 3CC9A 4DXJA 4GP1A 3VJ8A 2Z4YA 3WCMA 1PS1A 5B0IA 2E8XA 4H5CF 2Z52A 2FORA 3TS7A 5A0IA 4JYXA 3KRAB 4E1EA 3WJOA 3VJEA 2PS7A 4DZWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WKZ A;  3KRC B;  4GP2 A;  3Q2Q A;  4LA6 A;  2E91 A;  2P1C A;  4MC8 A;  3N5H F;  3OYR A;  4XQT F;  5EAU A;  5HN9 A;  2E94 A;  3AQC B;  4L2X F;  3VJ9 A;  3ACX A;  3WEI A;  4RXD A;  1VG4 A;  2Z4W A;  3MZV A;  4HD1 A;  4LUU A;  4XQR F;  3ZCD A;  4DWB A;  3RBM A;  3N5J F;  1N1B A;  4LLT A;  5C05 A;  5B0M A;  5ILD A;  5CG5 A;  2O1O A;  4KVD A;  5ILJ A;  4RXE A;  2E8T A;  1YHM A;  3LLW A;  5IL8 A;  1YYT A;  5ILH A;  3Q2Z A;  4NKF A;  2E8U A;  3AE0 A;  1YYS A;  3LJI A;  3TFN A;  4JXY A;  4LTV A;  5B03 A;  2DH4 A;  1WL2 A;  3OAC B;  4KK2 A;  3S4J A;  4PVX F;  3KBK A;  4KVI A;  5HN8 A;  1HXA A;  3N49 F;  3G4D A;  2AEL A;  3WJN A;  3TFP A;  1EZF A;  3OAB B;  3Q1O A;  1V4J A;  4NUA A;  5HNA A;  3SDV A;  5DHI A;  1YV5 A;  2F92 F;  5I1U A;  2ZEU A;  1RTR A;  2Q9Z A;  3N6K F;  5IKH A;  4OKZ A;  4OGU A;  2Z7I A;  4GAX A;  3QQV A;  1HM7 A;  5JUZ F;  5ILK A;  4N1Z F;  2E8W A;  1UBW A;  3WEG A;  1HXG A;  5IMP A;  5AHU B;  5IMI A;  3KRO B;  3LEE A;  3M00 A;  2Q9Y A;  3WC9 A;  3W7F A;  4JVJ F;  3N1W F;  3LVS A;  2PS6 A;  5DJR F;  2ZEV A;  3SAE A;  3V66 A;  1UBY A;  2AZL A;  3P8R A;  4LIX A;  5E8K A;  2F8C F;  5IM1 A;  5A0J A;  5DGM F;  1KIY A;  3N1V F;  3LG5 A;  3PDE A;  3DYH A;  4KQU A;  1V4H A;  2ZCQ A;  2OGD A;  1RQJ A;  3Q30 A;  2PS8 A;  2AEK A;  4PVY F;  4KQ5 A;  3LOM A;  4DI5 A;  3G4F A;  5DW7 A;  2ZY1 A;  3WCH A;  2FTZ A;  4LLS A;  4RNQ A;  3WEJ A;  3WCF A;  4KQS A;  5B0J A;  5B00 A;  4K10 A;  3VJC A;  1YYQ A;  3BNX A;  4NG6 A;  3V1X A;  4NFK F;  1V4E A;  3WJK A;  5CG6 A;  3WCD A;  3NF2 A;  3APZ A;  3ASX A;  4DWG A;  3EZ3 A;  4Q23 A;  2J5C A;  3DYG A;  3PH7 A;  3PYB A;  4EA2 A;  1N1Z A;  4KVW A;  5A0K A;  2F9K F;  1N22 A;  3ZMC A;  3TC1 A;  3KB9 A;  1ZW5 A;  4JXN A;  1N23 A;  4LZC A;  1VG7 A;  4NFJ F;  4KFA A;  4KKM A;  3WE9 A;  5IVG A;  2PS4 A;  2Q58 A;  1HXC A;  2J1P A;  4LTZ A;  4KPJ A;  3SDT A;  5IK6 A;  1DGP A;  3N0F A;  1WL0 A;  5DGN F;  4LA5 A;  1KIZ A;  3WCE A;  3KRF A;  1VG6 A;  2J1O A;  4EA0 A;  2E8V A;  5AFX A;  5DZ2 A;  4EA1 A;  4KPD A;  3QKC A;  1FPS A;  3SDU A;  4OKM A;  2AZK A;  3NPR A;  5H9D A;  5B0K A;  5JV0 F;  3M0G A;  5IK9 A;  5JV2 F;  3NPK A;  3PKO A;  3KRP A;  4P0V A;  4E9Z A;  3IBA A;  3EGT A;  5E8H A;  3B7L A;  3N3D A;  3RYW A;  2ONG A;  5IK0 A;  3N46 F;  2E95 A;  3NRI A;  2ZCS A;  1UBX A;  2F7M F;  5IKA A;  5B02 A;  3ZL6 A;  2OPN A;  5ERO A;  3M02 A;  3LMD A;  2E4O A;  3LZ9 A;  3RYE A;  5IL3 A;  3WCI A;  4JZX A;  1HM4 A;  3KRA A;  3WCJ A;  4RYP A;  4UMJ A;  4LXW A;  5JV1 F;  3ADZ A;  1WL1 A;  1YJ4 A;  4NKE A;  3KRC A;  3EFQ A;  1WY0 A;  1JFA A;  3WEH A;  1YYU A;  5B0L A;  5DGS F;  2AZJ A;  3LK5 A;  2RAH A;  3SDR A;  5E8L A;  3M9U A;  3LGZ B;  5ILZ A;  3ICN A;  4LZ0 A;  5ILY A;  3ZMB A;  3WCL A;  3P8L A;  4XQS F;  2F8Z F;  3LDW A;  1V4I A;  4F6X A;  2ZCR A;  4FP4 A;  5HN7 A;  2Z7H A;  3P5P A;  3PYA A;  2Z4X A;  2H8O A;  3N3L F;  3P41 A;  4H5D F;  5ER8 A;  3DYF A;  3WSA A;  5B01 A;  1VG3 A;  4P0X A;  1WL3 A;  4NFI F;  3VJD A;  3N45 F;  3CP6 A;  3M01 A;  5AYP A;  2Z78 A;  4KVY A;  1N20 A;  2QIS A;  3OAC A;  3VJB A;  2AET A;  1YYR A;  5ILI A;  2ONH A;  2Z50 A;  3OAB A;  4QPF A;  4F6V A;  1YHK A;  3UCA A;  3VJA A;  3WEF A;  3ACW A;  1V4K A;  3SDQ A;  1UBV A;  4DEM F;  2OA6 A;  3WCG A;  1YQ7 A;  4OMG A;  5DJP F;  2PS5 A;  4LZ3 A;  4ZQ8 A;  5DHK A;  5IMN A;  3KRO A;  3ICK A;  3ICZ A;  3WEK A;  4E9U A;  1N21 A;  3V1V A;  2E90 A;  2F89 F;  2EWG A;  2E93 A;  4LOB A;  3RMG A;  2ZCO A;  5EAT A;  3N0G A;  1RQI A;  1HX9 A;  4N9U A;  3ID0 A;  4LPH F;  4MC0 A;  2Z4Z A;  4H5E F;  3WCA A;  4KWD A;  5ERN A;  3LGK A;  2F94 F;  4WK5 A;  4OMH A;  4RXA A;  5IN8 A;  1WMW A;  3MAV A;  1DI1 A;  4F62 A;  4MC3 A;  2OPM A;  3WSB A;  3AQ0 A;  4DHD A;  3S9V A;  1VG2 A;  5DIQ F;  3TFV A;  3WCB A;  2I19 A;  4JZB A;  3KRF B;  3P5R A;  4QXS F;  3ICM A;  5AEL A;  5DJV F;  1N24 A;  4LFE A;  3WCC A;  3IPI A;  4RXC A;  4P0W A;  4LPG F;  1YHL A;  5JA0 F;  4LFV F;  5EAS A;  3KRP B;  2Z4V A;  5ERM A;  3BNY A;  5KSX F;  2Q80 A;  2E92 A;  3AQB B;  4FJQ A;  3CKE A;  4GA3 A;  1JFG A;  3LSN A;  2VF6 A;  4LFG A;  3ACY A;  4KUX A;  3ZOU A;  3CC9 A;  4DXJ A;  4GP1 A;  3VJ8 A;  2Z4Y A;  3WCM A;  1PS1 A;  5B0I A;  2E8X A;  4H5C F;  2Z52 A;  2FOR A;  3TS7 A;  5A0I A;  4JYX A;  3KRA B;  4E1E A;  3WJO A;  3VJE A;  2PS7 A;  4DZW A; 
#chains in the Genus database with same CATH topology
 1WKZ A;  3KRC B;  4GP2 A;  3Q2Q A;  4LA6 A;  2E91 A;  2P1C A;  4MC8 A;  3N5H F;  3OYR A;  4XQT F;  5EAU A;  5HN9 A;  2E94 A;  3AQC B;  4L2X F;  3VJ9 A;  3ACX A;  3WEI A;  4RXD A;  1VG4 A;  2Z4W A;  3MZV A;  4HD1 A;  4LUU A;  4XQR F;  3ZCD A;  4DWB A;  3RBM A;  3N5J F;  1N1B A;  4LLT A;  5C05 A;  5B0M A;  5ILD A;  5CG5 A;  2O1O A;  4KVD A;  5ILJ A;  4RXE A;  2E8T A;  1YHM A;  3LLW A;  5IL8 A;  1YYT A;  5ILH A;  3Q2Z A;  4NKF A;  2E8U A;  3AE0 A;  1YYS A;  3LJI A;  3TFN A;  4JXY A;  4LTV A;  5B03 A;  2DH4 A;  1WL2 A;  3OAC B;  4KK2 A;  3S4J A;  4PVX F;  3KBK A;  4KVI A;  5HN8 A;  1HXA A;  3N49 F;  3G4D A;  2AEL A;  3WJN A;  3TFP A;  1EZF A;  3OAB B;  3Q1O A;  1V4J A;  4NUA A;  5HNA A;  3SDV A;  5DHI A;  1YV5 A;  2F92 F;  5I1U A;  2ZEU A;  1RTR A;  2Q9Z A;  3N6K F;  5IKH A;  4OKZ A;  4OGU A;  2Z7I A;  4GAX A;  3QQV A;  1HM7 A;  5JUZ F;  5ILK A;  4N1Z F;  2E8W A;  1UBW A;  3WEG A;  1HXG A;  5IMP A;  5AHU B;  5IMI A;  3KRO B;  3LEE A;  3M00 A;  2Q9Y A;  3WC9 A;  3W7F A;  4JVJ F;  3N1W F;  3LVS A;  2PS6 A;  5DJR F;  2ZEV A;  3SAE A;  3V66 A;  1UBY A;  2AZL A;  3P8R A;  4LIX A;  5E8K A;  2F8C F;  5IM1 A;  5A0J A;  5DGM F;  1KIY A;  3N1V F;  3LG5 A;  3PDE A;  3DYH A;  4KQU A;  1V4H A;  2ZCQ A;  2OGD A;  1RQJ A;  3Q30 A;  2PS8 A;  2AEK A;  4PVY F;  4KQ5 A;  3LOM A;  4DI5 A;  3G4F A;  5DW7 A;  2ZY1 A;  3WCH A;  2FTZ A;  4LLS A;  4RNQ A;  3WEJ A;  3WCF A;  4KQS A;  5B0J A;  5B00 A;  4K10 A;  3VJC A;  1YYQ A;  3BNX A;  4NG6 A;  3V1X A;  4NFK F;  1V4E A;  3WJK A;  5CG6 A;  3WCD A;  3NF2 A;  3APZ A;  3ASX A;  4DWG A;  3EZ3 A;  4Q23 A;  2J5C A;  3DYG A;  3PH7 A;  3PYB A;  4EA2 A;  1N1Z A;  4KVW A;  5A0K A;  2F9K F;  1N22 A;  3ZMC A;  3TC1 A;  3KB9 A;  1ZW5 A;  4JXN A;  1N23 A;  4LZC A;  1VG7 A;  4NFJ F;  4KFA A;  4KKM A;  3WE9 A;  5IVG A;  2PS4 A;  2Q58 A;  1HXC A;  2J1P A;  4LTZ A;  4KPJ A;  3SDT A;  5IK6 A;  1DGP A;  3N0F A;  1WL0 A;  5DGN F;  4LA5 A;  1KIZ A;  3WCE A;  3KRF A;  1VG6 A;  2J1O A;  4EA0 A;  2E8V A;  5AFX A;  5DZ2 A;  4EA1 A;  4KPD A;  3QKC A;  1FPS A;  3SDU A;  4OKM A;  2AZK A;  3NPR A;  5H9D A;  5B0K A;  5JV0 F;  3M0G A;  5IK9 A;  5JV2 F;  3NPK A;  3PKO A;  3KRP A;  4P0V A;  4E9Z A;  3IBA A;  3EGT A;  5E8H A;  3B7L A;  3N3D A;  3RYW A;  2ONG A;  5IK0 A;  3N46 F;  2E95 A;  3NRI A;  2ZCS A;  1UBX A;  2F7M F;  5IKA A;  5B02 A;  3ZL6 A;  2OPN A;  5ERO A;  3M02 A;  3LMD A;  2E4O A;  3LZ9 A;  3RYE A;  5IL3 A;  3WCI A;  4JZX A;  1HM4 A;  3KRA A;  3WCJ A;  4RYP A;  4UMJ A;  4LXW A;  5JV1 F;  3ADZ A;  1WL1 A;  1YJ4 A;  4NKE A;  3KRC A;  3EFQ A;  1WY0 A;  1JFA A;  3WEH A;  1YYU A;  5B0L A;  5DGS F;  2AZJ A;  3LK5 A;  2RAH A;  3SDR A;  5E8L A;  3M9U A;  3LGZ B;  5ILZ A;  3ICN A;  4LZ0 A;  5ILY A;  3ZMB A;  3WCL A;  3P8L A;  4XQS F;  2F8Z F;  3LDW A;  1V4I A;  4F6X A;  2ZCR A;  4FP4 A;  5HN7 A;  2Z7H A;  3P5P A;  3PYA A;  2Z4X A;  2H8O A;  3N3L F;  3P41 A;  4H5D F;  5ER8 A;  3DYF A;  3WSA A;  5B01 A;  1VG3 A;  4P0X A;  1WL3 A;  4NFI F;  3VJD A;  3N45 F;  3CP6 A;  3M01 A;  5AYP A;  2Z78 A;  4KVY A;  1N20 A;  2QIS A;  3OAC A;  3VJB A;  2AET A;  1YYR A;  5ILI A;  2ONH A;  2Z50 A;  3OAB A;  4QPF A;  4F6V A;  1YHK A;  3UCA A;  3VJA A;  3WEF A;  3ACW A;  1V4K A;  3SDQ A;  1UBV A;  4DEM F;  2OA6 A;  3WCG A;  1YQ7 A;  4OMG A;  5DJP F;  2PS5 A;  4LZ3 A;  4ZQ8 A;  5DHK A;  5IMN A;  3KRO A;  3ICK A;  3ICZ A;  3WEK A;  4E9U A;  1N21 A;  3V1V A;  2E90 A;  2F89 F;  2EWG A;  2E93 A;  4LOB A;  3RMG A;  2ZCO A;  5EAT A;  3N0G A;  1RQI A;  1HX9 A;  4N9U A;  3ID0 A;  4LPH F;  4MC0 A;  2Z4Z A;  4H5E F;  3WCA A;  4KWD A;  5ERN A;  3LGK A;  2F94 F;  4WK5 A;  4OMH A;  4RXA A;  5IN8 A;  1WMW A;  3MAV A;  1DI1 A;  4F62 A;  4MC3 A;  2OPM A;  3WSB A;  3AQ0 A;  4DHD A;  3S9V A;  1VG2 A;  5DIQ F;  3TFV A;  3WCB A;  2I19 A;  4JZB A;  3KRF B;  3P5R A;  4QXS F;  3ICM A;  5AEL A;  5DJV F;  1N24 A;  4LFE A;  3WCC A;  3IPI A;  4RXC A;  4P0W A;  4LPG F;  1YHL A;  5JA0 F;  4LFV F;  5EAS A;  3KRP B;  2Z4V A;  5ERM A;  3BNY A;  5KSX F;  2Q80 A;  2E92 A;  3AQB B;  4FJQ A;  3CKE A;  4GA3 A;  1JFG A;  3LSN A;  2VF6 A;  4LFG A;  3ACY A;  4KUX A;  3ZOU A;  3CC9 A;  4DXJ A;  4GP1 A;  3VJ8 A;  2Z4Y A;  3WCM A;  1PS1 A;  5B0I A;  2E8X A;  4H5C F;  2Z52 A;  2FOR A;  3TS7 A;  5A0I A;  4JYX A;  3KRA B;  4E1E A;  3WJO A;  3VJE A;  2PS7 A;  4DZW A; 
#chains in the Genus database with same CATH homology
 1WKZ A;  3KRC B;  4GP2 A;  3Q2Q A;  4LA6 A;  2E91 A;  2P1C A;  4MC8 A;  3N5H F;  3OYR A;  4XQT F;  5EAU A;  5HN9 A;  2E94 A;  3AQC B;  4L2X F;  3VJ9 A;  3ACX A;  3WEI A;  4RXD A;  1VG4 A;  2Z4W A;  3MZV A;  4HD1 A;  4LUU A;  4XQR F;  3ZCD A;  4DWB A;  3RBM A;  3N5J F;  1N1B A;  4LLT A;  5C05 A;  5B0M A;  5ILD A;  5CG5 A;  2O1O A;  4KVD A;  5ILJ A;  4RXE A;  2E8T A;  1YHM A;  3LLW A;  5IL8 A;  1YYT A;  5ILH A;  3Q2Z A;  4NKF A;  2E8U A;  3AE0 A;  1YYS A;  3LJI A;  3TFN A;  4JXY A;  4LTV A;  5B03 A;  2DH4 A;  1WL2 A;  3OAC B;  4KK2 A;  3S4J A;  4PVX F;  3KBK A;  4KVI A;  5HN8 A;  1HXA A;  3N49 F;  3G4D A;  2AEL A;  3WJN A;  3TFP A;  1EZF A;  3OAB B;  3Q1O A;  1V4J A;  4NUA A;  5HNA A;  3SDV A;  5DHI A;  1YV5 A;  2F92 F;  5I1U A;  2ZEU A;  1RTR A;  2Q9Z A;  3N6K F;  5IKH A;  4OKZ A;  4OGU A;  2Z7I A;  4GAX A;  3QQV A;  1HM7 A;  5JUZ F;  5ILK A;  4N1Z F;  2E8W A;  1UBW A;  3WEG A;  1HXG A;  5IMP A;  5AHU B;  5IMI A;  3KRO B;  3LEE A;  3M00 A;  2Q9Y A;  3WC9 A;  3W7F A;  4JVJ F;  3N1W F;  3LVS A;  2PS6 A;  5DJR F;  2ZEV A;  3SAE A;  3V66 A;  1UBY A;  2AZL A;  3P8R A;  4LIX A;  5E8K A;  2F8C F;  5IM1 A;  5A0J A;  5DGM F;  1KIY A;  3N1V F;  3LG5 A;  3PDE A;  3DYH A;  4KQU A;  1V4H A;  2ZCQ A;  2OGD A;  1RQJ A;  3Q30 A;  2PS8 A;  2AEK A;  4PVY F;  4KQ5 A;  3LOM A;  4DI5 A;  3G4F A;  5DW7 A;  2ZY1 A;  3WCH A;  2FTZ A;  4LLS A;  4RNQ A;  3WEJ A;  3WCF A;  4KQS A;  5B0J A;  5B00 A;  4K10 A;  3VJC A;  1YYQ A;  3BNX A;  4NG6 A;  3V1X A;  4NFK F;  1V4E A;  3WJK A;  5CG6 A;  3WCD A;  3NF2 A;  3APZ A;  3ASX A;  4DWG A;  3EZ3 A;  4Q23 A;  2J5C A;  3DYG A;  3PH7 A;  3PYB A;  4EA2 A;  1N1Z A;  4KVW A;  5A0K A;  2F9K F;  1N22 A;  3ZMC A;  3TC1 A;  3KB9 A;  1ZW5 A;  4JXN A;  1N23 A;  4LZC A;  1VG7 A;  4NFJ F;  4KFA A;  4KKM A;  3WE9 A;  5IVG A;  2PS4 A;  2Q58 A;  1HXC A;  2J1P A;  4LTZ A;  4KPJ A;  3SDT A;  5IK6 A;  1DGP A;  3N0F A;  1WL0 A;  5DGN F;  4LA5 A;  1KIZ A;  3WCE A;  3KRF A;  1VG6 A;  2J1O A;  4EA0 A;  2E8V A;  5AFX A;  5DZ2 A;  4EA1 A;  4KPD A;  3QKC A;  1FPS A;  3SDU A;  4OKM A;  2AZK A;  3NPR A;  5H9D A;  5B0K A;  5JV0 F;  3M0G A;  5IK9 A;  5JV2 F;  3NPK A;  3PKO A;  3KRP A;  4P0V A;  4E9Z A;  3IBA A;  3EGT A;  5E8H A;  3B7L A;  3N3D A;  3RYW A;  2ONG A;  5IK0 A;  3N46 F;  2E95 A;  3NRI A;  2ZCS A;  1UBX A;  2F7M F;  5IKA A;  5B02 A;  3ZL6 A;  2OPN A;  5ERO A;  3M02 A;  3LMD A;  2E4O A;  3LZ9 A;  3RYE A;  5IL3 A;  3WCI A;  4JZX A;  1HM4 A;  3KRA A;  3WCJ A;  4RYP A;  4UMJ A;  4LXW A;  5JV1 F;  3ADZ A;  1WL1 A;  1YJ4 A;  4NKE A;  3KRC A;  3EFQ A;  1WY0 A;  1JFA A;  3WEH A;  1YYU A;  5B0L A;  5DGS F;  2AZJ A;  3LK5 A;  2RAH A;  3SDR A;  5E8L A;  3M9U A;  3LGZ B;  5ILZ A;  3ICN A;  4LZ0 A;  5ILY A;  3ZMB A;  3WCL A;  3P8L A;  4XQS F;  2F8Z F;  3LDW A;  1V4I A;  4F6X A;  2ZCR A;  4FP4 A;  5HN7 A;  2Z7H A;  3P5P A;  3PYA A;  2Z4X A;  2H8O A;  3N3L F;  3P41 A;  4H5D F;  5ER8 A;  3DYF A;  3WSA A;  5B01 A;  1VG3 A;  4P0X A;  1WL3 A;  4NFI F;  3VJD A;  3N45 F;  3CP6 A;  3M01 A;  5AYP A;  2Z78 A;  4KVY A;  1N20 A;  2QIS A;  3OAC A;  3VJB A;  2AET A;  1YYR A;  5ILI A;  2ONH A;  2Z50 A;  3OAB A;  4QPF A;  4F6V A;  1YHK A;  3UCA A;  3VJA A;  3WEF A;  3ACW A;  1V4K A;  3SDQ A;  1UBV A;  4DEM F;  2OA6 A;  3WCG A;  1YQ7 A;  4OMG A;  5DJP F;  2PS5 A;  4LZ3 A;  4ZQ8 A;  5DHK A;  5IMN A;  3KRO A;  3ICK A;  3ICZ A;  3WEK A;  4E9U A;  1N21 A;  3V1V A;  2E90 A;  2F89 F;  2EWG A;  2E93 A;  4LOB A;  3RMG A;  2ZCO A;  5EAT A;  3N0G A;  1RQI A;  1HX9 A;  4N9U A;  3ID0 A;  4LPH F;  4MC0 A;  2Z4Z A;  4H5E F;  3WCA A;  4KWD A;  5ERN A;  3LGK A;  2F94 F;  4WK5 A;  4OMH A;  4RXA A;  5IN8 A;  1WMW A;  3MAV A;  1DI1 A;  4F62 A;  4MC3 A;  2OPM A;  3WSB A;  3AQ0 A;  4DHD A;  3S9V A;  1VG2 A;  5DIQ F;  3TFV A;  3WCB A;  2I19 A;  4JZB A;  3KRF B;  3P5R A;  4QXS F;  3ICM A;  5AEL A;  5DJV F;  1N24 A;  4LFE A;  3WCC A;  3IPI A;  4RXC A;  4P0W A;  4LPG F;  1YHL A;  5JA0 F;  4LFV F;  5EAS A;  3KRP B;  2Z4V A;  5ERM A;  3BNY A;  5KSX F;  2Q80 A;  2E92 A;  3AQB B;  4FJQ A;  3CKE A;  4GA3 A;  1JFG A;  3LSN A;  2VF6 A;  4LFG A;  3ACY A;  4KUX A;  3ZOU A;  3CC9 A;  4DXJ A;  4GP1 A;  3VJ8 A;  2Z4Y A;  3WCM A;  1PS1 A;  5B0I A;  2E8X A;  4H5C F;  2Z52 A;  2FOR A;  3TS7 A;  5A0I A;  4JYX A;  3KRA B;  4E1E A;  3WJO A;  3VJE A;  2PS7 A;  4DZW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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