2P1CA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-210
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
367
structure length
357
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma brucei
molecule keywords Farnesyl pyrophosphate synthase
total genus 146
structure length 357
sequence length 367
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2007-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2p1cA00
5ILKA 4KKMA 5IM1A 4P0WA 3M02A 3LLWA 4E9ZA 3LEEA 3ZCDA 3ICZA 5DJVF 5DJPF 5KSXF 4F62A 4P0XA 3PKOA 3B7LA 4RXEA 5CG6A 5DHKA 4MC0A 2F9KF 2Z4XA 4HD1A 1KIYA 1HXGA 4RYPA 3WJNA 4FP4A 1N21A 1RQJA 4OMGA 2PS5A 4LA5A 2ZCRA 3LZ9A 2AZKA 4LXWA 3TFNA 4JXYA 4OKMA 1DI1A 4RXAA 2FORA 2Z52A 4LZCA 4E9UA 1JFGA 3P8LA 5DGMF 3KRCB 5B02A 5E8KA 5IMIA 1YHMA 2E8XA 4LIXA 3SAEA 3WEFA 1JFAA 1DGPA 4KQ5A 3VJBA 1YQ7A 4LFVF 4N1ZF 4Q23A 3P41A 4LLSA 5IMNA 4JXNA 2ONHA 5B01A 4PVYF 5ILHA 3P5RA 3SDQA 4KK2A 5JUZF 3AQCB 3N5HF 4JVJF 5IL3A 4LTVA 2Z4WA 3LGZB 3WEGA 3ZL6A 1YYUA 2F8ZF 5IKAA 3N0GA 2Z7IA 5EROA 4JYXA 3MAVA 3SDUA 3ICMA 4KPJA 3KRCA 1KIZA 5DW7A 3LG5A 3AQ0A 3OACB 1HM7A 4LPHF 4OKZA 2Q80A 1HXCA 1UBYA 3PYAA 4F6XA 3P8RA 4GAXA 5ILDA 2Z4VA 3RMGA 4LZ3A 1N24A 3WJKA 4L2XF 3PH7A 1WL2A 4LLTA 1RTRA 1WY0A 3WEIA 4H5EF 3ACWA 2OPNA 5DZ2A 4RNQA 1FPSA 3N6KF 4H5CF 2OA6A 4GA3A 5IL8A 2AETA 5B03A 1V4IA 2RAHA 4P0VA 4DWBA 3OACA 5IK0A 1HM4A 2PS8A 3VJEA 3QKCA 5ERMA 5JA0F 5ILZA 1UBXA 3VJ9A 1RQIA 1EZFA 3WCFA 4EA2A 4GP2A 4KVWA 3WCAA 2J5CA 5A0KA 3LOMA 5C05A 3WEJA 5CG5A 3WCEA 5IKHA 1V4JA 1PS1A 3WE9A 3WCHA 5A0JA 3WCDA 1WKZA 3WEKA 3WCLA 1WL1A 3IPIA 1N22A 1V4HA 2J1OA 1YYTA 4F6VA 1YV5A 5JV2F 4NFJF 3RBMA 1VG7A 2I19A 1YYQA 4N9UA 3WCGA 4NG6A 2AELA 5B0JA 4RXCA 4DEMF 4LA6A 4KWDA 3TC1A 3LDWA 4KQSA 1N1ZA 4KVIA 3WCCA 5HN7A 5B0MA 3WCMA 4DXJA 1WL0A 2E8TA 3M0GA 2E8UA 3MZVA 5ERNA 4NFIF 3N1VF 3N3LF 2E95A 4DZWA 5IN8A 5ILJA 4WK5A 2E91A 3N46F 4OMHA 2Q9YA 2ZEUA 3KRAB 3OABB 3KBKA 3SDVA 1YHKA 3CC9A 3WC9A 4E1EA 3SDRA 2E92A 3ACYA 5JV1F 3G4DA 3LJIA 3TFPA 3S4JA 3IBAA 2E94A 3EGTA 4MC3A 2Z50A 3M00A 4H5DF 4NKEA 5DGSF 3N3DA 2ZCOA 3NF2A 3LK5A 5ILYA 5H9DA 3N5JF 2F8CF 1N20A 2Z78A 4NUAA 3KRAA 3OABA 4JZBA 5B0LA 4LPGF 5AELA 1HXAA 3LGKA 5DJRF 5E8LA 1UBWA 1VG3A 3KRPA 2AZLA 4KVDA 1WMWA 2FTZA 2ZCQA 4XQSF 3W7FA 5EATA 3ZOUA 2E93A 3ZMCA 3UCAA 5ER8A 3EFQA 3VJCA 4KFAA 4RXDA 5AYPA 4XQTF 4LZ0A 3AE0A 1N23A 1YYRA 1ZW5A 4KVYA 3LSNA 3Q30A 2Q58A 3ICNA 2Z4YA 3KROB 3KRFA 3SDTA 2Z7HA 4QXSF 1WL3A 3WCJA 3APZA 3LVSA 1V4KA 3N49F 4LUUA 1HX9A 2F94F 2F89F 1V4EA 1YJ4A 3NPRA 2AZJA 2O1OA 2J1PA 4NFKF 2F92F 3N1WF 4UMJA 3BNXA 5EAUA 3KB9A 2E90A 5B0IA 3N0FA 3V66A 4PVXF 1YYSA 4KQUA 5HNAA 3AQBB 3Q2ZA 2OGDA 3WCBA 3NRIA 2PS4A 1N1BA 4LFGA 2ONGA 4LTZA 3TFVA 3KROA 2AEKA 4FJQA 5HN9A 5I1UA 5AFXA 2ZY1A 3M9UA 3ZMBA 4GP1A 1VG6A 4XQRF 3EZ3A 3WEHA 2E4OA 3PYBA 4KPDA 3PDEA 2VF6A 3S9VA 5DHIA 5ILIA 2P1CA 5IVGA 2E8WA 3QQVA 3DYGA 3NPKA 5HN8A 1VG2A 3V1XA 5DIQF 1YHLA 5IK6A 5JV0F 3VJ8A 2EWGA 3RYEA 2PS6A 3LMDA 4MC8A 4OGUA 3V1VA 3CKEA 3KRPB 5AHUB 4DWGA 3ASXA 3ADZA 5A0IA 4LOBA 4DHDA 4DI5A 4ZQ8A 2F7MF 2ZEVA 2ZCSA 3BNYA 4K10A 3WSBA 5IK9A 3VJAA 3N45F 4EA1A 3CP6A 3ICKA 5E8HA 3DYFA 5IMPA 4KUXA 2PS7A 5B0KA 3DYHA 3M01A 4QPFA 5EASA 3G4FA 4LFEA 3KRFB 3TS7A 3Q2QA 3VJDA 3WSAA 1UBVA 5B00A 2DH4A 3OYRA 5DGNF 2Z4ZA 4JZXA 2H8OA 2OPMA 2Q9ZA 3P5PA 2E8VA 4NKFA 3ACXA 3Q1OA 3ID0A 3RYWA 3WCIA 1VG4A 3WJOA 2QISA 4EA0A
chains in the Genus database with same CATH superfamily
5ILKA 4KKMA 5IM1A 4P0WA 3M02A 3LLWA 4E9ZA 3LEEA 3ZCDA 3ICZA 5DJVF 5DJPF 5KSXF 4F62A 4P0XA 3PKOA 3B7LA 4RXEA 5CG6A 5DHKA 4MC0A 2F9KF 2Z4XA 4HD1A 1KIYA 1HXGA 4RYPA 3WJNA 4FP4A 1N21A 1RQJA 4OMGA 2PS5A 4LA5A 2ZCRA 3LZ9A 2AZKA 4LXWA 3TFNA 4JXYA 4OKMA 1DI1A 4RXAA 2FORA 2Z52A 4LZCA 4E9UA 1JFGA 3P8LA 5DGMF 3KRCB 5B02A 5E8KA 5IMIA 1YHMA 2E8XA 4LIXA 3SAEA 3WEFA 1JFAA 1DGPA 4KQ5A 3VJBA 1YQ7A 4LFVF 4N1ZF 4Q23A 3P41A 4LLSA 5IMNA 4JXNA 2ONHA 5B01A 4PVYF 5ILHA 3P5RA 3SDQA 4KK2A 5JUZF 3AQCB 3N5HF 4JVJF 5IL3A 4LTVA 2Z4WA 3LGZB 3WEGA 3ZL6A 1YYUA 2F8ZF 5IKAA 3N0GA 2Z7IA 5EROA 4JYXA 3MAVA 3SDUA 3ICMA 4KPJA 3KRCA 1KIZA 5DW7A 3LG5A 3AQ0A 3OACB 1HM7A 4LPHF 4OKZA 2Q80A 1HXCA 1UBYA 3PYAA 4F6XA 3P8RA 4GAXA 5ILDA 2Z4VA 3RMGA 4LZ3A 1N24A 3WJKA 4L2XF 3PH7A 1WL2A 4LLTA 1RTRA 1WY0A 3WEIA 4H5EF 3ACWA 2OPNA 5DZ2A 4RNQA 1FPSA 3N6KF 4H5CF 2OA6A 4GA3A 5IL8A 2AETA 5B03A 1V4IA 2RAHA 4P0VA 4DWBA 3OACA 5IK0A 1HM4A 2PS8A 3VJEA 3QKCA 5ERMA 5JA0F 5ILZA 1UBXA 3VJ9A 1RQIA 1EZFA 3WCFA 4EA2A 4GP2A 4KVWA 3WCAA 2J5CA 5A0KA 3LOMA 5C05A 3WEJA 5CG5A 3WCEA 5IKHA 1V4JA 1PS1A 3WE9A 3WCHA 5A0JA 3WCDA 1WKZA 3WEKA 3WCLA 1WL1A 3IPIA 1N22A 1V4HA 2J1OA 1YYTA 4F6VA 1YV5A 5JV2F 4NFJF 3RBMA 1VG7A 2I19A 1YYQA 4N9UA 3WCGA 4NG6A 2AELA 5B0JA 4RXCA 4DEMF 4LA6A 4KWDA 3TC1A 3LDWA 4KQSA 1N1ZA 4KVIA 3WCCA 5HN7A 5B0MA 3WCMA 4DXJA 1WL0A 2E8TA 3M0GA 2E8UA 3MZVA 5ERNA 4NFIF 3N1VF 3N3LF 2E95A 4DZWA 5IN8A 5ILJA 4WK5A 2E91A 3N46F 4OMHA 2Q9YA 2ZEUA 3KRAB 3OABB 3KBKA 3SDVA 1YHKA 3CC9A 3WC9A 4E1EA 3SDRA 2E92A 3ACYA 5JV1F 3G4DA 3LJIA 3TFPA 3S4JA 3IBAA 2E94A 3EGTA 4MC3A 2Z50A 3M00A 4H5DF 4NKEA 5DGSF 3N3DA 2ZCOA 3NF2A 3LK5A 5ILYA 5H9DA 3N5JF 2F8CF 1N20A 2Z78A 4NUAA 3KRAA 3OABA 4JZBA 5B0LA 4LPGF 5AELA 1HXAA 3LGKA 5DJRF 5E8LA 1UBWA 1VG3A 3KRPA 2AZLA 4KVDA 1WMWA 2FTZA 2ZCQA 4XQSF 3W7FA 5EATA 3ZOUA 2E93A 3ZMCA 3UCAA 5ER8A 3EFQA 3VJCA 4KFAA 4RXDA 5AYPA 4XQTF 4LZ0A 3AE0A 1N23A 1YYRA 1ZW5A 4KVYA 3LSNA 3Q30A 2Q58A 3ICNA 2Z4YA 3KROB 3KRFA 3SDTA 2Z7HA 4QXSF 1WL3A 3WCJA 3APZA 3LVSA 1V4KA 3N49F 4LUUA 1HX9A 2F94F 2F89F 1V4EA 1YJ4A 3NPRA 2AZJA 2O1OA 2J1PA 4NFKF 2F92F 3N1WF 4UMJA 3BNXA 5EAUA 3KB9A 2E90A 5B0IA 3N0FA 3V66A 4PVXF 1YYSA 4KQUA 5HNAA 3AQBB 3Q2ZA 2OGDA 3WCBA 3NRIA 2PS4A 1N1BA 4LFGA 2ONGA 4LTZA 3TFVA 3KROA 2AEKA 4FJQA 5HN9A 5I1UA 5AFXA 2ZY1A 3M9UA 3ZMBA 4GP1A 1VG6A 4XQRF 3EZ3A 3WEHA 2E4OA 3PYBA 4KPDA 3PDEA 2VF6A 3S9VA 5DHIA 5ILIA 2P1CA 5IVGA 2E8WA 3QQVA 3DYGA 3NPKA 5HN8A 1VG2A 3V1XA 5DIQF 1YHLA 5IK6A 5JV0F 3VJ8A 2EWGA 3RYEA 2PS6A 3LMDA 4MC8A 4OGUA 3V1VA 3CKEA 3KRPB 5AHUB 4DWGA 3ASXA 3ADZA 5A0IA 4LOBA 4DHDA 4DI5A 4ZQ8A 2F7MF 2ZEVA 2ZCSA 3BNYA 4K10A 3WSBA 5IK9A 3VJAA 3N45F 4EA1A 3CP6A 3ICKA 5E8HA 3DYFA 5IMPA 4KUXA 2PS7A 5B0KA 3DYHA 3M01A 4QPFA 5EASA 3G4FA 4LFEA 3KRFB 3TS7A 3Q2QA 3VJDA 3WSAA 1UBVA 5B00A 2DH4A 3OYRA 5DGNF 2Z4ZA 4JZXA 2H8OA 2OPMA 2Q9ZA 3P5PA 2E8VA 4NKFA 3ACXA 3Q1OA 3ID0A 3RYWA 3WCIA 1VG4A 3WJOA 2QISA 4EA0A
chains in the Genus database with same CATH topology
5ILKA 4KKMA 5IM1A 4P0WA 3M02A 3LLWA 4E9ZA 3LEEA 3ZCDA 3ICZA 5DJVF 5DJPF 5KSXF 4F62A 4P0XA 3PKOA 3B7LA 4RXEA 5CG6A 5DHKA 4MC0A 2F9KF 2Z4XA 4HD1A 1KIYA 1HXGA 4RYPA 3WJNA 4FP4A 1N21A 1RQJA 4OMGA 2PS5A 4LA5A 2ZCRA 3LZ9A 2AZKA 4LXWA 3TFNA 4JXYA 4OKMA 1DI1A 4RXAA 2FORA 2Z52A 4LZCA 4E9UA 1JFGA 3P8LA 5DGMF 3KRCB 5B02A 5E8KA 5IMIA 1YHMA 2E8XA 4LIXA 3SAEA 3WEFA 1JFAA 1DGPA 4KQ5A 3VJBA 1YQ7A 4LFVF 4N1ZF 4Q23A 3P41A 4LLSA 5IMNA 4JXNA 2ONHA 5B01A 4PVYF 5ILHA 3P5RA 3SDQA 4KK2A 5JUZF 3AQCB 3N5HF 4JVJF 5IL3A 4LTVA 2Z4WA 3LGZB 3WEGA 3ZL6A 1YYUA 2F8ZF 5IKAA 3N0GA 2Z7IA 5EROA 4JYXA 3MAVA 3SDUA 3ICMA 4KPJA 3KRCA 1KIZA 5DW7A 3LG5A 3AQ0A 3OACB 1HM7A 4LPHF 4OKZA 2Q80A 1HXCA 1UBYA 3PYAA 4F6XA 3P8RA 4GAXA 5ILDA 2Z4VA 3RMGA 4LZ3A 1N24A 3WJKA 4L2XF 3PH7A 1WL2A 4LLTA 1RTRA 1WY0A 3WEIA 4H5EF 3ACWA 2OPNA 5DZ2A 4RNQA 1FPSA 3N6KF 4H5CF 2OA6A 4GA3A 5IL8A 2AETA 5B03A 1V4IA 2RAHA 4P0VA 4DWBA 3OACA 5IK0A 1HM4A 2PS8A 3VJEA 3QKCA 5ERMA 5JA0F 5ILZA 1UBXA 3VJ9A 1RQIA 1EZFA 3WCFA 4EA2A 4GP2A 4KVWA 3WCAA 2J5CA 5A0KA 3LOMA 5C05A 3WEJA 5CG5A 3WCEA 5IKHA 1V4JA 1PS1A 3WE9A 3WCHA 5A0JA 3WCDA 1WKZA 3WEKA 3WCLA 1WL1A 3IPIA 1N22A 1V4HA 2J1OA 1YYTA 4F6VA 1YV5A 5JV2F 4NFJF 3RBMA 1VG7A 2I19A 1YYQA 4N9UA 3WCGA 4NG6A 2AELA 5B0JA 4RXCA 4DEMF 4LA6A 4KWDA 3TC1A 3LDWA 4KQSA 1N1ZA 4KVIA 3WCCA 5HN7A 5B0MA 3WCMA 4DXJA 1WL0A 2E8TA 3M0GA 2E8UA 3MZVA 5ERNA 4NFIF 3N1VF 3N3LF 2E95A 4DZWA 5IN8A 5ILJA 4WK5A 2E91A 3N46F 4OMHA 2Q9YA 2ZEUA 3KRAB 3OABB 3KBKA 3SDVA 1YHKA 3CC9A 3WC9A 4E1EA 3SDRA 2E92A 3ACYA 5JV1F 3G4DA 3LJIA 3TFPA 3S4JA 3IBAA 2E94A 3EGTA 4MC3A 2Z50A 3M00A 4H5DF 4NKEA 5DGSF 3N3DA 2ZCOA 3NF2A 3LK5A 5ILYA 5H9DA 3N5JF 2F8CF 1N20A 2Z78A 4NUAA 3KRAA 3OABA 4JZBA 5B0LA 4LPGF 5AELA 1HXAA 3LGKA 5DJRF 5E8LA 1UBWA 1VG3A 3KRPA 2AZLA 4KVDA 1WMWA 2FTZA 2ZCQA 4XQSF 3W7FA 5EATA 3ZOUA 2E93A 3ZMCA 3UCAA 5ER8A 3EFQA 3VJCA 4KFAA 4RXDA 5AYPA 4XQTF 4LZ0A 3AE0A 1N23A 1YYRA 1ZW5A 4KVYA 3LSNA 3Q30A 2Q58A 3ICNA 2Z4YA 3KROB 3KRFA 3SDTA 2Z7HA 4QXSF 1WL3A 3WCJA 3APZA 3LVSA 1V4KA 3N49F 4LUUA 1HX9A 2F94F 2F89F 1V4EA 1YJ4A 3NPRA 2AZJA 2O1OA 2J1PA 4NFKF 2F92F 3N1WF 4UMJA 3BNXA 5EAUA 3KB9A 2E90A 5B0IA 3N0FA 3V66A 4PVXF 1YYSA 4KQUA 5HNAA 3AQBB 3Q2ZA 2OGDA 3WCBA 3NRIA 2PS4A 1N1BA 4LFGA 2ONGA 4LTZA 3TFVA 3KROA 2AEKA 4FJQA 5HN9A 5I1UA 5AFXA 2ZY1A 3M9UA 3ZMBA 4GP1A 1VG6A 4XQRF 3EZ3A 3WEHA 2E4OA 3PYBA 4KPDA 3PDEA 2VF6A 3S9VA 5DHIA 5ILIA 2P1CA 5IVGA 2E8WA 3QQVA 3DYGA 3NPKA 5HN8A 1VG2A 3V1XA 5DIQF 1YHLA 5IK6A 5JV0F 3VJ8A 2EWGA 3RYEA 2PS6A 3LMDA 4MC8A 4OGUA 3V1VA 3CKEA 3KRPB 5AHUB 4DWGA 3ASXA 3ADZA 5A0IA 4LOBA 4DHDA 4DI5A 4ZQ8A 2F7MF 2ZEVA 2ZCSA 3BNYA 4K10A 3WSBA 5IK9A 3VJAA 3N45F 4EA1A 3CP6A 3ICKA 5E8HA 3DYFA 5IMPA 4KUXA 2PS7A 5B0KA 3DYHA 3M01A 4QPFA 5EASA 3G4FA 4LFEA 3KRFB 3TS7A 3Q2QA 3VJDA 3WSAA 1UBVA 5B00A 2DH4A 3OYRA 5DGNF 2Z4ZA 4JZXA 2H8OA 2OPMA 2Q9ZA 3P5PA 2E8VA 4NKFA 3ACXA 3Q1OA 3ID0A 3RYWA 3WCIA 1VG4A 3WJOA 2QISA 4EA0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ILK A;  4KKM A;  5IM1 A;  4P0W A;  3M02 A;  3LLW A;  4E9Z A;  3LEE A;  3ZCD A;  3ICZ A;  5DJV F;  5DJP F;  5KSX F;  4F62 A;  4P0X A;  3PKO A;  3B7L A;  4RXE A;  5CG6 A;  5DHK A;  4MC0 A;  2F9K F;  2Z4X A;  4HD1 A;  1KIY A;  1HXG A;  4RYP A;  3WJN A;  4FP4 A;  1N21 A;  1RQJ A;  4OMG A;  2PS5 A;  4LA5 A;  2ZCR A;  3LZ9 A;  2AZK A;  4LXW A;  3TFN A;  4JXY A;  4OKM A;  1DI1 A;  4RXA A;  2FOR A;  2Z52 A;  4LZC A;  4E9U A;  1JFG A;  3P8L A;  5DGM F;  3KRC B;  5B02 A;  5E8K A;  5IMI A;  1YHM A;  2E8X A;  4LIX A;  3SAE A;  3WEF A;  1JFA A;  1DGP A;  4KQ5 A;  3VJB A;  1YQ7 A;  4LFV F;  4N1Z F;  4Q23 A;  3P41 A;  4LLS A;  5IMN A;  4JXN A;  2ONH A;  5B01 A;  4PVY F;  5ILH A;  3P5R A;  3SDQ A;  4KK2 A;  5JUZ F;  3AQC B;  3N5H F;  4JVJ F;  5IL3 A;  4LTV A;  2Z4W A;  3LGZ B;  3WEG A;  3ZL6 A;  1YYU A;  2F8Z F;  5IKA A;  3N0G A;  2Z7I A;  5ERO A;  4JYX A;  3MAV A;  3SDU A;  3ICM A;  4KPJ A;  3KRC A;  1KIZ A;  5DW7 A;  3LG5 A;  3AQ0 A;  3OAC B;  1HM7 A;  4LPH F;  4OKZ A;  2Q80 A;  1HXC A;  1UBY A;  3PYA A;  4F6X A;  3P8R A;  4GAX A;  5ILD A;  2Z4V A;  3RMG A;  4LZ3 A;  1N24 A;  3WJK A;  4L2X F;  3PH7 A;  1WL2 A;  4LLT A;  1RTR A;  1WY0 A;  3WEI A;  4H5E F;  3ACW A;  2OPN A;  5DZ2 A;  4RNQ A;  1FPS A;  3N6K F;  4H5C F;  2OA6 A;  4GA3 A;  5IL8 A;  2AET A;  5B03 A;  1V4I A;  2RAH A;  4P0V A;  4DWB A;  3OAC A;  5IK0 A;  1HM4 A;  2PS8 A;  3VJE A;  3QKC A;  5ERM A;  5JA0 F;  5ILZ A;  1UBX A;  3VJ9 A;  1RQI A;  1EZF A;  3WCF A;  4EA2 A;  4GP2 A;  4KVW A;  3WCA A;  2J5C A;  5A0K A;  3LOM A;  5C05 A;  3WEJ A;  5CG5 A;  3WCE A;  5IKH A;  1V4J A;  1PS1 A;  3WE9 A;  3WCH A;  5A0J A;  3WCD A;  1WKZ A;  3WEK A;  3WCL A;  1WL1 A;  3IPI A;  1N22 A;  1V4H A;  2J1O A;  1YYT A;  4F6V A;  1YV5 A;  5JV2 F;  4NFJ F;  3RBM A;  1VG7 A;  2I19 A;  1YYQ A;  4N9U A;  3WCG A;  4NG6 A;  2AEL A;  5B0J A;  4RXC A;  4DEM F;  4LA6 A;  4KWD A;  3TC1 A;  3LDW A;  4KQS A;  1N1Z A;  4KVI A;  3WCC A;  5HN7 A;  5B0M A;  3WCM A;  4DXJ A;  1WL0 A;  2E8T A;  3M0G A;  2E8U A;  3MZV A;  5ERN A;  4NFI F;  3N1V F;  3N3L F;  2E95 A;  4DZW A;  5IN8 A;  5ILJ A;  4WK5 A;  2E91 A;  3N46 F;  4OMH A;  2Q9Y A;  2ZEU A;  3KRA B;  3OAB B;  3KBK A;  3SDV A;  1YHK A;  3CC9 A;  3WC9 A;  4E1E A;  3SDR A;  2E92 A;  3ACY A;  5JV1 F;  3G4D A;  3LJI A;  3TFP A;  3S4J A;  3IBA A;  2E94 A;  3EGT A;  4MC3 A;  2Z50 A;  3M00 A;  4H5D F;  4NKE A;  5DGS F;  3N3D A;  2ZCO A;  3NF2 A;  3LK5 A;  5ILY A;  5H9D A;  3N5J F;  2F8C F;  1N20 A;  2Z78 A;  4NUA A;  3KRA A;  3OAB A;  4JZB A;  5B0L A;  4LPG F;  5AEL A;  1HXA A;  3LGK A;  5DJR F;  5E8L A;  1UBW A;  1VG3 A;  3KRP A;  2AZL A;  4KVD A;  1WMW A;  2FTZ A;  2ZCQ A;  4XQS F;  3W7F A;  5EAT A;  3ZOU A;  2E93 A;  3ZMC A;  3UCA A;  5ER8 A;  3EFQ A;  3VJC A;  4KFA A;  4RXD A;  5AYP A;  4XQT F;  4LZ0 A;  3AE0 A;  1N23 A;  1YYR A;  1ZW5 A;  4KVY A;  3LSN A;  3Q30 A;  2Q58 A;  3ICN A;  2Z4Y A;  3KRO B;  3KRF A;  3SDT A;  2Z7H A;  4QXS F;  1WL3 A;  3WCJ A;  3APZ A;  3LVS A;  1V4K A;  3N49 F;  4LUU A;  1HX9 A;  2F94 F;  2F89 F;  1V4E A;  1YJ4 A;  3NPR A;  2AZJ A;  2O1O A;  2J1P A;  4NFK F;  2F92 F;  3N1W F;  4UMJ A;  3BNX A;  5EAU A;  3KB9 A;  2E90 A;  5B0I A;  3N0F A;  3V66 A;  4PVX F;  1YYS A;  4KQU A;  5HNA A;  3AQB B;  3Q2Z A;  2OGD A;  3WCB A;  3NRI A;  2PS4 A;  1N1B A;  4LFG A;  2ONG A;  4LTZ A;  3TFV A;  3KRO A;  2AEK A;  4FJQ A;  5HN9 A;  5I1U A;  5AFX A;  2ZY1 A;  3M9U A;  3ZMB A;  4GP1 A;  1VG6 A;  4XQR F;  3EZ3 A;  3WEH A;  2E4O A;  3PYB A;  4KPD A;  3PDE A;  2VF6 A;  3S9V A;  5DHI A;  5ILI A;  2P1C A;  5IVG A;  2E8W A;  3QQV A;  3DYG A;  3NPK A;  5HN8 A;  1VG2 A;  3V1X A;  5DIQ F;  1YHL A;  5IK6 A;  5JV0 F;  3VJ8 A;  2EWG A;  3RYE A;  2PS6 A;  3LMD A;  4MC8 A;  4OGU A;  3V1V A;  3CKE A;  3KRP B;  5AHU B;  4DWG A;  3ASX A;  3ADZ A;  5A0I A;  4LOB A;  4DHD A;  4DI5 A;  4ZQ8 A;  2F7M F;  2ZEV A;  2ZCS A;  3BNY A;  4K10 A;  3WSB A;  5IK9 A;  3VJA A;  3N45 F;  4EA1 A;  3CP6 A;  3ICK A;  5E8H A;  3DYF A;  5IMP A;  4KUX A;  2PS7 A;  5B0K A;  3DYH A;  3M01 A;  4QPF A;  5EAS A;  3G4F A;  4LFE A;  3KRF B;  3TS7 A;  3Q2Q A;  3VJD A;  3WSA A;  1UBV A;  5B00 A;  2DH4 A;  3OYR A;  5DGN F;  2Z4Z A;  4JZX A;  2H8O A;  2OPM A;  2Q9Z A;  3P5P A;  2E8V A;  4NKF A;  3ACX A;  3Q1O A;  3ID0 A;  3RYW A;  3WCI A;  1VG4 A;  3WJO A;  2QIS A;  4EA0 A; 
#chains in the Genus database with same CATH topology
 5ILK A;  4KKM A;  5IM1 A;  4P0W A;  3M02 A;  3LLW A;  4E9Z A;  3LEE A;  3ZCD A;  3ICZ A;  5DJV F;  5DJP F;  5KSX F;  4F62 A;  4P0X A;  3PKO A;  3B7L A;  4RXE A;  5CG6 A;  5DHK A;  4MC0 A;  2F9K F;  2Z4X A;  4HD1 A;  1KIY A;  1HXG A;  4RYP A;  3WJN A;  4FP4 A;  1N21 A;  1RQJ A;  4OMG A;  2PS5 A;  4LA5 A;  2ZCR A;  3LZ9 A;  2AZK A;  4LXW A;  3TFN A;  4JXY A;  4OKM A;  1DI1 A;  4RXA A;  2FOR A;  2Z52 A;  4LZC A;  4E9U A;  1JFG A;  3P8L A;  5DGM F;  3KRC B;  5B02 A;  5E8K A;  5IMI A;  1YHM A;  2E8X A;  4LIX A;  3SAE A;  3WEF A;  1JFA A;  1DGP A;  4KQ5 A;  3VJB A;  1YQ7 A;  4LFV F;  4N1Z F;  4Q23 A;  3P41 A;  4LLS A;  5IMN A;  4JXN A;  2ONH A;  5B01 A;  4PVY F;  5ILH A;  3P5R A;  3SDQ A;  4KK2 A;  5JUZ F;  3AQC B;  3N5H F;  4JVJ F;  5IL3 A;  4LTV A;  2Z4W A;  3LGZ B;  3WEG A;  3ZL6 A;  1YYU A;  2F8Z F;  5IKA A;  3N0G A;  2Z7I A;  5ERO A;  4JYX A;  3MAV A;  3SDU A;  3ICM A;  4KPJ A;  3KRC A;  1KIZ A;  5DW7 A;  3LG5 A;  3AQ0 A;  3OAC B;  1HM7 A;  4LPH F;  4OKZ A;  2Q80 A;  1HXC A;  1UBY A;  3PYA A;  4F6X A;  3P8R A;  4GAX A;  5ILD A;  2Z4V A;  3RMG A;  4LZ3 A;  1N24 A;  3WJK A;  4L2X F;  3PH7 A;  1WL2 A;  4LLT A;  1RTR A;  1WY0 A;  3WEI A;  4H5E F;  3ACW A;  2OPN A;  5DZ2 A;  4RNQ A;  1FPS A;  3N6K F;  4H5C F;  2OA6 A;  4GA3 A;  5IL8 A;  2AET A;  5B03 A;  1V4I A;  2RAH A;  4P0V A;  4DWB A;  3OAC A;  5IK0 A;  1HM4 A;  2PS8 A;  3VJE A;  3QKC A;  5ERM A;  5JA0 F;  5ILZ A;  1UBX A;  3VJ9 A;  1RQI A;  1EZF A;  3WCF A;  4EA2 A;  4GP2 A;  4KVW A;  3WCA A;  2J5C A;  5A0K A;  3LOM A;  5C05 A;  3WEJ A;  5CG5 A;  3WCE A;  5IKH A;  1V4J A;  1PS1 A;  3WE9 A;  3WCH A;  5A0J A;  3WCD A;  1WKZ A;  3WEK A;  3WCL A;  1WL1 A;  3IPI A;  1N22 A;  1V4H A;  2J1O A;  1YYT A;  4F6V A;  1YV5 A;  5JV2 F;  4NFJ F;  3RBM A;  1VG7 A;  2I19 A;  1YYQ A;  4N9U A;  3WCG A;  4NG6 A;  2AEL A;  5B0J A;  4RXC A;  4DEM F;  4LA6 A;  4KWD A;  3TC1 A;  3LDW A;  4KQS A;  1N1Z A;  4KVI A;  3WCC A;  5HN7 A;  5B0M A;  3WCM A;  4DXJ A;  1WL0 A;  2E8T A;  3M0G A;  2E8U A;  3MZV A;  5ERN A;  4NFI F;  3N1V F;  3N3L F;  2E95 A;  4DZW A;  5IN8 A;  5ILJ A;  4WK5 A;  2E91 A;  3N46 F;  4OMH A;  2Q9Y A;  2ZEU A;  3KRA B;  3OAB B;  3KBK A;  3SDV A;  1YHK A;  3CC9 A;  3WC9 A;  4E1E A;  3SDR A;  2E92 A;  3ACY A;  5JV1 F;  3G4D A;  3LJI A;  3TFP A;  3S4J A;  3IBA A;  2E94 A;  3EGT A;  4MC3 A;  2Z50 A;  3M00 A;  4H5D F;  4NKE A;  5DGS F;  3N3D A;  2ZCO A;  3NF2 A;  3LK5 A;  5ILY A;  5H9D A;  3N5J F;  2F8C F;  1N20 A;  2Z78 A;  4NUA A;  3KRA A;  3OAB A;  4JZB A;  5B0L A;  4LPG F;  5AEL A;  1HXA A;  3LGK A;  5DJR F;  5E8L A;  1UBW A;  1VG3 A;  3KRP A;  2AZL A;  4KVD A;  1WMW A;  2FTZ A;  2ZCQ A;  4XQS F;  3W7F A;  5EAT A;  3ZOU A;  2E93 A;  3ZMC A;  3UCA A;  5ER8 A;  3EFQ A;  3VJC A;  4KFA A;  4RXD A;  5AYP A;  4XQT F;  4LZ0 A;  3AE0 A;  1N23 A;  1YYR A;  1ZW5 A;  4KVY A;  3LSN A;  3Q30 A;  2Q58 A;  3ICN A;  2Z4Y A;  3KRO B;  3KRF A;  3SDT A;  2Z7H A;  4QXS F;  1WL3 A;  3WCJ A;  3APZ A;  3LVS A;  1V4K A;  3N49 F;  4LUU A;  1HX9 A;  2F94 F;  2F89 F;  1V4E A;  1YJ4 A;  3NPR A;  2AZJ A;  2O1O A;  2J1P A;  4NFK F;  2F92 F;  3N1W F;  4UMJ A;  3BNX A;  5EAU A;  3KB9 A;  2E90 A;  5B0I A;  3N0F A;  3V66 A;  4PVX F;  1YYS A;  4KQU A;  5HNA A;  3AQB B;  3Q2Z A;  2OGD A;  3WCB A;  3NRI A;  2PS4 A;  1N1B A;  4LFG A;  2ONG A;  4LTZ A;  3TFV A;  3KRO A;  2AEK A;  4FJQ A;  5HN9 A;  5I1U A;  5AFX A;  2ZY1 A;  3M9U A;  3ZMB A;  4GP1 A;  1VG6 A;  4XQR F;  3EZ3 A;  3WEH A;  2E4O A;  3PYB A;  4KPD A;  3PDE A;  2VF6 A;  3S9V A;  5DHI A;  5ILI A;  2P1C A;  5IVG A;  2E8W A;  3QQV A;  3DYG A;  3NPK A;  5HN8 A;  1VG2 A;  3V1X A;  5DIQ F;  1YHL A;  5IK6 A;  5JV0 F;  3VJ8 A;  2EWG A;  3RYE A;  2PS6 A;  3LMD A;  4MC8 A;  4OGU A;  3V1V A;  3CKE A;  3KRP B;  5AHU B;  4DWG A;  3ASX A;  3ADZ A;  5A0I A;  4LOB A;  4DHD A;  4DI5 A;  4ZQ8 A;  2F7M F;  2ZEV A;  2ZCS A;  3BNY A;  4K10 A;  3WSB A;  5IK9 A;  3VJA A;  3N45 F;  4EA1 A;  3CP6 A;  3ICK A;  5E8H A;  3DYF A;  5IMP A;  4KUX A;  2PS7 A;  5B0K A;  3DYH A;  3M01 A;  4QPF A;  5EAS A;  3G4F A;  4LFE A;  3KRF B;  3TS7 A;  3Q2Q A;  3VJD A;  3WSA A;  1UBV A;  5B00 A;  2DH4 A;  3OYR A;  5DGN F;  2Z4Z A;  4JZX A;  2H8O A;  2OPM A;  2Q9Z A;  3P5P A;  2E8V A;  4NKF A;  3ACX A;  3Q1O A;  3ID0 A;  3RYW A;  3WCI A;  1VG4 A;  3WJO A;  2QIS A;  4EA0 A; 
#chains in the Genus database with same CATH homology
 5ILK A;  4KKM A;  5IM1 A;  4P0W A;  3M02 A;  3LLW A;  4E9Z A;  3LEE A;  3ZCD A;  3ICZ A;  5DJV F;  5DJP F;  5KSX F;  4F62 A;  4P0X A;  3PKO A;  3B7L A;  4RXE A;  5CG6 A;  5DHK A;  4MC0 A;  2F9K F;  2Z4X A;  4HD1 A;  1KIY A;  1HXG A;  4RYP A;  3WJN A;  4FP4 A;  1N21 A;  1RQJ A;  4OMG A;  2PS5 A;  4LA5 A;  2ZCR A;  3LZ9 A;  2AZK A;  4LXW A;  3TFN A;  4JXY A;  4OKM A;  1DI1 A;  4RXA A;  2FOR A;  2Z52 A;  4LZC A;  4E9U A;  1JFG A;  3P8L A;  5DGM F;  3KRC B;  5B02 A;  5E8K A;  5IMI A;  1YHM A;  2E8X A;  4LIX A;  3SAE A;  3WEF A;  1JFA A;  1DGP A;  4KQ5 A;  3VJB A;  1YQ7 A;  4LFV F;  4N1Z F;  4Q23 A;  3P41 A;  4LLS A;  5IMN A;  4JXN A;  2ONH A;  5B01 A;  4PVY F;  5ILH A;  3P5R A;  3SDQ A;  4KK2 A;  5JUZ F;  3AQC B;  3N5H F;  4JVJ F;  5IL3 A;  4LTV A;  2Z4W A;  3LGZ B;  3WEG A;  3ZL6 A;  1YYU A;  2F8Z F;  5IKA A;  3N0G A;  2Z7I A;  5ERO A;  4JYX A;  3MAV A;  3SDU A;  3ICM A;  4KPJ A;  3KRC A;  1KIZ A;  5DW7 A;  3LG5 A;  3AQ0 A;  3OAC B;  1HM7 A;  4LPH F;  4OKZ A;  2Q80 A;  1HXC A;  1UBY A;  3PYA A;  4F6X A;  3P8R A;  4GAX A;  5ILD A;  2Z4V A;  3RMG A;  4LZ3 A;  1N24 A;  3WJK A;  4L2X F;  3PH7 A;  1WL2 A;  4LLT A;  1RTR A;  1WY0 A;  3WEI A;  4H5E F;  3ACW A;  2OPN A;  5DZ2 A;  4RNQ A;  1FPS A;  3N6K F;  4H5C F;  2OA6 A;  4GA3 A;  5IL8 A;  2AET A;  5B03 A;  1V4I A;  2RAH A;  4P0V A;  4DWB A;  3OAC A;  5IK0 A;  1HM4 A;  2PS8 A;  3VJE A;  3QKC A;  5ERM A;  5JA0 F;  5ILZ A;  1UBX A;  3VJ9 A;  1RQI A;  1EZF A;  3WCF A;  4EA2 A;  4GP2 A;  4KVW A;  3WCA A;  2J5C A;  5A0K A;  3LOM A;  5C05 A;  3WEJ A;  5CG5 A;  3WCE A;  5IKH A;  1V4J A;  1PS1 A;  3WE9 A;  3WCH A;  5A0J A;  3WCD A;  1WKZ A;  3WEK A;  3WCL A;  1WL1 A;  3IPI A;  1N22 A;  1V4H A;  2J1O A;  1YYT A;  4F6V A;  1YV5 A;  5JV2 F;  4NFJ F;  3RBM A;  1VG7 A;  2I19 A;  1YYQ A;  4N9U A;  3WCG A;  4NG6 A;  2AEL A;  5B0J A;  4RXC A;  4DEM F;  4LA6 A;  4KWD A;  3TC1 A;  3LDW A;  4KQS A;  1N1Z A;  4KVI A;  3WCC A;  5HN7 A;  5B0M A;  3WCM A;  4DXJ A;  1WL0 A;  2E8T A;  3M0G A;  2E8U A;  3MZV A;  5ERN A;  4NFI F;  3N1V F;  3N3L F;  2E95 A;  4DZW A;  5IN8 A;  5ILJ A;  4WK5 A;  2E91 A;  3N46 F;  4OMH A;  2Q9Y A;  2ZEU A;  3KRA B;  3OAB B;  3KBK A;  3SDV A;  1YHK A;  3CC9 A;  3WC9 A;  4E1E A;  3SDR A;  2E92 A;  3ACY A;  5JV1 F;  3G4D A;  3LJI A;  3TFP A;  3S4J A;  3IBA A;  2E94 A;  3EGT A;  4MC3 A;  2Z50 A;  3M00 A;  4H5D F;  4NKE A;  5DGS F;  3N3D A;  2ZCO A;  3NF2 A;  3LK5 A;  5ILY A;  5H9D A;  3N5J F;  2F8C F;  1N20 A;  2Z78 A;  4NUA A;  3KRA A;  3OAB A;  4JZB A;  5B0L A;  4LPG F;  5AEL A;  1HXA A;  3LGK A;  5DJR F;  5E8L A;  1UBW A;  1VG3 A;  3KRP A;  2AZL A;  4KVD A;  1WMW A;  2FTZ A;  2ZCQ A;  4XQS F;  3W7F A;  5EAT A;  3ZOU A;  2E93 A;  3ZMC A;  3UCA A;  5ER8 A;  3EFQ A;  3VJC A;  4KFA A;  4RXD A;  5AYP A;  4XQT F;  4LZ0 A;  3AE0 A;  1N23 A;  1YYR A;  1ZW5 A;  4KVY A;  3LSN A;  3Q30 A;  2Q58 A;  3ICN A;  2Z4Y A;  3KRO B;  3KRF A;  3SDT A;  2Z7H A;  4QXS F;  1WL3 A;  3WCJ A;  3APZ A;  3LVS A;  1V4K A;  3N49 F;  4LUU A;  1HX9 A;  2F94 F;  2F89 F;  1V4E A;  1YJ4 A;  3NPR A;  2AZJ A;  2O1O A;  2J1P A;  4NFK F;  2F92 F;  3N1W F;  4UMJ A;  3BNX A;  5EAU A;  3KB9 A;  2E90 A;  5B0I A;  3N0F A;  3V66 A;  4PVX F;  1YYS A;  4KQU A;  5HNA A;  3AQB B;  3Q2Z A;  2OGD A;  3WCB A;  3NRI A;  2PS4 A;  1N1B A;  4LFG A;  2ONG A;  4LTZ A;  3TFV A;  3KRO A;  2AEK A;  4FJQ A;  5HN9 A;  5I1U A;  5AFX A;  2ZY1 A;  3M9U A;  3ZMB A;  4GP1 A;  1VG6 A;  4XQR F;  3EZ3 A;  3WEH A;  2E4O A;  3PYB A;  4KPD A;  3PDE A;  2VF6 A;  3S9V A;  5DHI A;  5ILI A;  2P1C A;  5IVG A;  2E8W A;  3QQV A;  3DYG A;  3NPK A;  5HN8 A;  1VG2 A;  3V1X A;  5DIQ F;  1YHL A;  5IK6 A;  5JV0 F;  3VJ8 A;  2EWG A;  3RYE A;  2PS6 A;  3LMD A;  4MC8 A;  4OGU A;  3V1V A;  3CKE A;  3KRP B;  5AHU B;  4DWG A;  3ASX A;  3ADZ A;  5A0I A;  4LOB A;  4DHD A;  4DI5 A;  4ZQ8 A;  2F7M F;  2ZEV A;  2ZCS A;  3BNY A;  4K10 A;  3WSB A;  5IK9 A;  3VJA A;  3N45 F;  4EA1 A;  3CP6 A;  3ICK A;  5E8H A;  3DYF A;  5IMP A;  4KUX A;  2PS7 A;  5B0K A;  3DYH A;  3M01 A;  4QPF A;  5EAS A;  3G4F A;  4LFE A;  3KRF B;  3TS7 A;  3Q2Q A;  3VJD A;  3WSA A;  1UBV A;  5B00 A;  2DH4 A;  3OYR A;  5DGN F;  2Z4Z A;  4JZX A;  2H8O A;  2OPM A;  2Q9Z A;  3P5P A;  2E8V A;  4NKF A;  3ACX A;  3Q1O A;  3ID0 A;  3RYW A;  3WCI A;  1VG4 A;  3WJO A;  2QIS A;  4EA0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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