3NRIA

Crystal structure of the c(30) carotenoid dehydrosqualene synthase from s. aureus complexed with dehydrosqualene (dhs)
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
284
structure length
279
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of action and inhibition of dehydrosqualene synthase.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords Dehydrosqualene synthase
total genus 116
structure length 279
sequence length 284
ec nomenclature
pdb deposition date 2010-06-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3nriA00
2O1OA 1UBWA 4LIXA 2OPMA 3TFNA 3WEKA 1N21A 3SDVA 1RQJA 1YYUA 1YHKA 2Z78A 4JZXA 3VJAA 3WCEA 1V4KA 3Q30A 4H5CF 2PS8A 5IM1A 1YJ4A 2AETA 3ZMBA 2RAHA 4UMJA 5I1UA 4GA3A 5DHIA 4LXWA 4LA6A 3EZ3A 3N1WF 4LZCA 5IN8A 4H5DF 1JFGA 5ILDA 4XQSF 2Z50A 3PH7A 4E9ZA 5IK6A 2H8OA 3KRPB 3AQBB 5DJRF 1KIZA 4OGUA 1WL3A 4LZ3A 4KVYA 2OPNA 1JFAA 1WY0A 4LPHF 3G4FA 2OGDA 3OACA 2Z4WA 1V4HA 3B7LA 3PDEA 4HD1A 3WCAA 3WEIA 3N1VF 3DYFA 3G4DA 3CC9A 5A0IA 3MAVA 5EATA 3LG5A 5ERMA 1YYRA 4RXEA 5AELA 2PS4A 4NG6A 4LUUA 2E94A 5B0IA 1N24A 2E8UA 1N1BA 5JUZF 4PVYF 2AELA 4DEMF 1KIYA 4KWDA 3WCJA 1VG3A 3OYRA 1VG4A 1RQIA 1UBVA 3ZCDA 3LK5A 3WCFA 3WJKA 1VG2A 2F92F 4DWGA 1HXAA 4LTVA 3WEFA 4KQSA 4RYPA 2ZCQA 3KRCB 4KK2A 3PKOA 1V4IA 3N0FA 4Q23A 5ILIA 3N5HF 3RYWA 2AZLA 1V4EA 2Q58A 4OMGA 4KFAA 3LGKA 5IMIA 2E91A 3KROA 3S9VA 4DHDA 3OABA 2AZJA 3V1VA 3LEEA 2E90A 4QPFA 4KVIA 4EA1A 3LGZB 2F9KF 3SDQA 4QXSF 3NPKA 2I19A 3V66A 5CG5A 3PYAA 5E8LA 3Q2ZA 4JYXA 2E8VA 2VF6A 3ASXA 4LTZA 4LLTA 3ZOUA 3AQ0A 5DGMF 3WCLA 4RXAA 3CKEA 4L2XF 3N5JF 2E92A 1WL1A 3P5RA 4LFVF 3LMDA 3ZMCA 5CG6A 1YYSA 5HN7A 5ILYA 5IVGA 1DGPA 2ZY1A 3WCIA 3TFPA 4MC8A 5IKHA 3APZA 1V4JA 3ACWA 4P0XA 2FTZA 3ICNA 5DIQF 4KUXA 4LZ0A 5EROA 1DI1A 5IK9A 1YYTA 3ICZA 3ZL6A 3KRFA 4E9UA 4NUAA 1ZW5A 3OACB 3W7FA 5IL3A 3M01A 4N9UA 3WCDA 3RYEA 4P0WA 3VJCA 3WSBA 2QISA 1N22A 1VG7A 3M9UA 5JV0F 4PVXF 3ID0A 3VJ9A 5B0KA 4FJQA 4OKZA 3M02A 1HM7A 1YHMA 3MZVA 4RXCA 2Q9YA 5B0LA 3WJOA 4LFEA 5EASA 4E1EA 3DYHA 5IMNA 4RXDA 2PS6A 5ILHA 4WK5A 2PS5A 3WC9A 4MC0A 3SDTA 5H9DA 3V1XA 4JVJF 3N3DA 3WE9A 4F6VA 5ILKA 5ERNA 3ADZA 3P5PA 3AE0A 3LZ9A 4NFJF 4LFGA 3IBAA 3SDUA 5IKAA 3RBMA 3KBKA 5KSXF 2F94F 3NPRA 3CP6A 4EA0A 5HNAA 2E4OA 5EAUA 2ZCRA 3KROB 4F6XA 1WL2A 4LLSA 1FPSA 3OABB 4KPJA 4ZQ8A 1EZFA 4KVDA 2ZCOA 4LA5A 3KRCA 3KRAA 3SAEA 3WJNA 3LLWA 4GP1A 1WMWA 3LJIA 3NF2A 4KQ5A 3BNXA 2P1CA 4LOBA 1RTRA 3LSNA 5ER8A 5B02A 5AYPA 4NFIF 4P0VA 2F8CF 2F7MF 1UBYA 2ZCSA 2Z7IA 5IMPA 4H5EF 1YYQA 1N23A 3EFQA 2Z4VA 5A0KA 2Z52A 3VJDA 4DI5A 3M00A 2J5CA 3VJBA 1VG6A 2E93A 5AHUB 3P8LA 3Q2QA 2EWGA 4GP2A 3LDWA 2Z4YA 1HXCA 4LPGF 3UCAA 3ACXA 4XQRF 1YQ7A 5DHKA 2Z4XA 5ILJA 4DXJA 1YV5A 2Z4ZA 3KRFB 3QKCA 3WEHA 3SDRA 3IPIA 4KQUA 4K10A 5IK0A 3VJ8A 5B0MA 3ICKA 3BNYA 3KRPA 5HN9A 3TC1A 2PS7A 4RNQA 2ONGA 5DGNF 4MC3A 5JA0F 3TS7A 4DZWA 2ZEVA 4F62A 3Q1OA 3AQCB 3WCBA 5A0JA 3WCHA 3N49F 3PYBA 5AFXA 5IL8A 3TFVA 3N46F 4KPDA 3P8RA 2J1PA 2OA6A 3KB9A 4JXNA 3ICMA 4NKFA 5HN8A 3P41A 3WSAA 2Q80A 4NFKF 1HM4A 3WCCA 5DW7A 3N3LF 3M0GA 5JV2F 5E8HA 1UBXA 3N6KF 4NKEA 5DJPF 4OKMA 3N0GA 5E8KA 3EGTA 4EA2A 4DWBA 1WKZA 3WCGA 4JZBA 1PS1A 5C05A 2ZEUA 2Q9ZA 2FORA 2E95A 5DZ2A 4KKMA 1HX9A 5JV1F 4OMHA 3DYGA 2DH4A 2AZKA 1HXGA 4N1ZF 2E8WA 4FP4A 4GAXA 2E8TA 1N1ZA 4JXYA 2F8ZF 3LOMA 2Z7HA 3RMGA 3QQVA 3N45F 3VJEA 3NRIA 2AEKA 2E8XA 4KVWA 5DGSF 5DJVF 3WEGA 4XQTF 2J1OA 1N20A 5B0JA 3WEJA 3S4JA 3KRAB 5B00A 5B03A 5ILZA 2ONHA 1YHLA 2F89F 5B01A 3WCMA 3ACYA 1WL0A 3LVSA
chains in the Genus database with same CATH superfamily
2O1OA 1UBWA 4LIXA 2OPMA 3TFNA 3WEKA 1N21A 3SDVA 1RQJA 1YYUA 1YHKA 2Z78A 4JZXA 3VJAA 3WCEA 1V4KA 3Q30A 4H5CF 2PS8A 5IM1A 1YJ4A 2AETA 3ZMBA 2RAHA 4UMJA 5I1UA 4GA3A 5DHIA 4LXWA 4LA6A 3EZ3A 3N1WF 4LZCA 5IN8A 4H5DF 1JFGA 5ILDA 4XQSF 2Z50A 3PH7A 4E9ZA 5IK6A 2H8OA 3KRPB 3AQBB 5DJRF 1KIZA 4OGUA 1WL3A 4LZ3A 4KVYA 2OPNA 1JFAA 1WY0A 4LPHF 3G4FA 2OGDA 3OACA 2Z4WA 1V4HA 3B7LA 3PDEA 4HD1A 3WCAA 3WEIA 3N1VF 3DYFA 3G4DA 3CC9A 5A0IA 3MAVA 5EATA 3LG5A 5ERMA 1YYRA 4RXEA 5AELA 2PS4A 4NG6A 4LUUA 2E94A 5B0IA 1N24A 2E8UA 1N1BA 5JUZF 4PVYF 2AELA 4DEMF 1KIYA 4KWDA 3WCJA 1VG3A 3OYRA 1VG4A 1RQIA 1UBVA 3ZCDA 3LK5A 3WCFA 3WJKA 1VG2A 2F92F 4DWGA 1HXAA 4LTVA 3WEFA 4KQSA 4RYPA 2ZCQA 3KRCB 4KK2A 3PKOA 1V4IA 3N0FA 4Q23A 5ILIA 3N5HF 3RYWA 2AZLA 1V4EA 2Q58A 4OMGA 4KFAA 3LGKA 5IMIA 2E91A 3KROA 3S9VA 4DHDA 3OABA 2AZJA 3V1VA 3LEEA 2E90A 4QPFA 4KVIA 4EA1A 3LGZB 2F9KF 3SDQA 4QXSF 3NPKA 2I19A 3V66A 5CG5A 3PYAA 5E8LA 3Q2ZA 4JYXA 2E8VA 2VF6A 3ASXA 4LTZA 4LLTA 3ZOUA 3AQ0A 5DGMF 3WCLA 4RXAA 3CKEA 4L2XF 3N5JF 2E92A 1WL1A 3P5RA 4LFVF 3LMDA 3ZMCA 5CG6A 1YYSA 5HN7A 5ILYA 5IVGA 1DGPA 2ZY1A 3WCIA 3TFPA 4MC8A 5IKHA 3APZA 1V4JA 3ACWA 4P0XA 2FTZA 3ICNA 5DIQF 4KUXA 4LZ0A 5EROA 1DI1A 5IK9A 1YYTA 3ICZA 3ZL6A 3KRFA 4E9UA 4NUAA 1ZW5A 3OACB 3W7FA 5IL3A 3M01A 4N9UA 3WCDA 3RYEA 4P0WA 3VJCA 3WSBA 2QISA 1N22A 1VG7A 3M9UA 5JV0F 4PVXF 3ID0A 3VJ9A 5B0KA 4FJQA 4OKZA 3M02A 1HM7A 1YHMA 3MZVA 4RXCA 2Q9YA 5B0LA 3WJOA 4LFEA 5EASA 4E1EA 3DYHA 5IMNA 4RXDA 2PS6A 5ILHA 4WK5A 2PS5A 3WC9A 4MC0A 3SDTA 5H9DA 3V1XA 4JVJF 3N3DA 3WE9A 4F6VA 5ILKA 5ERNA 3ADZA 3P5PA 3AE0A 3LZ9A 4NFJF 4LFGA 3IBAA 3SDUA 5IKAA 3RBMA 3KBKA 5KSXF 2F94F 3NPRA 3CP6A 4EA0A 5HNAA 2E4OA 5EAUA 2ZCRA 3KROB 4F6XA 1WL2A 4LLSA 1FPSA 3OABB 4KPJA 4ZQ8A 1EZFA 4KVDA 2ZCOA 4LA5A 3KRCA 3KRAA 3SAEA 3WJNA 3LLWA 4GP1A 1WMWA 3LJIA 3NF2A 4KQ5A 3BNXA 2P1CA 4LOBA 1RTRA 3LSNA 5ER8A 5B02A 5AYPA 4NFIF 4P0VA 2F8CF 2F7MF 1UBYA 2ZCSA 2Z7IA 5IMPA 4H5EF 1YYQA 1N23A 3EFQA 2Z4VA 5A0KA 2Z52A 3VJDA 4DI5A 3M00A 2J5CA 3VJBA 1VG6A 2E93A 5AHUB 3P8LA 3Q2QA 2EWGA 4GP2A 3LDWA 2Z4YA 1HXCA 4LPGF 3UCAA 3ACXA 4XQRF 1YQ7A 5DHKA 2Z4XA 5ILJA 4DXJA 1YV5A 2Z4ZA 3KRFB 3QKCA 3WEHA 3SDRA 3IPIA 4KQUA 4K10A 5IK0A 3VJ8A 5B0MA 3ICKA 3BNYA 3KRPA 5HN9A 3TC1A 2PS7A 4RNQA 2ONGA 5DGNF 4MC3A 5JA0F 3TS7A 4DZWA 2ZEVA 4F62A 3Q1OA 3AQCB 3WCBA 5A0JA 3WCHA 3N49F 3PYBA 5AFXA 5IL8A 3TFVA 3N46F 4KPDA 3P8RA 2J1PA 2OA6A 3KB9A 4JXNA 3ICMA 4NKFA 5HN8A 3P41A 3WSAA 2Q80A 4NFKF 1HM4A 3WCCA 5DW7A 3N3LF 3M0GA 5JV2F 5E8HA 1UBXA 3N6KF 4NKEA 5DJPF 4OKMA 3N0GA 5E8KA 3EGTA 4EA2A 4DWBA 1WKZA 3WCGA 4JZBA 1PS1A 5C05A 2ZEUA 2Q9ZA 2FORA 2E95A 5DZ2A 4KKMA 1HX9A 5JV1F 4OMHA 3DYGA 2DH4A 2AZKA 1HXGA 4N1ZF 2E8WA 4FP4A 4GAXA 2E8TA 1N1ZA 4JXYA 2F8ZF 3LOMA 2Z7HA 3RMGA 3QQVA 3N45F 3VJEA 3NRIA 2AEKA 2E8XA 4KVWA 5DGSF 5DJVF 3WEGA 4XQTF 2J1OA 1N20A 5B0JA 3WEJA 3S4JA 3KRAB 5B00A 5B03A 5ILZA 2ONHA 1YHLA 2F89F 5B01A 3WCMA 3ACYA 1WL0A 3LVSA
chains in the Genus database with same CATH topology
2O1OA 1UBWA 4LIXA 2OPMA 3TFNA 3WEKA 1N21A 3SDVA 1RQJA 1YYUA 1YHKA 2Z78A 4JZXA 3VJAA 3WCEA 1V4KA 3Q30A 4H5CF 2PS8A 5IM1A 1YJ4A 2AETA 3ZMBA 2RAHA 4UMJA 5I1UA 4GA3A 5DHIA 4LXWA 4LA6A 3EZ3A 3N1WF 4LZCA 5IN8A 4H5DF 1JFGA 5ILDA 4XQSF 2Z50A 3PH7A 4E9ZA 5IK6A 2H8OA 3KRPB 3AQBB 5DJRF 1KIZA 4OGUA 1WL3A 4LZ3A 4KVYA 2OPNA 1JFAA 1WY0A 4LPHF 3G4FA 2OGDA 3OACA 2Z4WA 1V4HA 3B7LA 3PDEA 4HD1A 3WCAA 3WEIA 3N1VF 3DYFA 3G4DA 3CC9A 5A0IA 3MAVA 5EATA 3LG5A 5ERMA 1YYRA 4RXEA 5AELA 2PS4A 4NG6A 4LUUA 2E94A 5B0IA 1N24A 2E8UA 1N1BA 5JUZF 4PVYF 2AELA 4DEMF 1KIYA 4KWDA 3WCJA 1VG3A 3OYRA 1VG4A 1RQIA 1UBVA 3ZCDA 3LK5A 3WCFA 3WJKA 1VG2A 2F92F 4DWGA 1HXAA 4LTVA 3WEFA 4KQSA 4RYPA 2ZCQA 3KRCB 4KK2A 3PKOA 1V4IA 3N0FA 4Q23A 5ILIA 3N5HF 3RYWA 2AZLA 1V4EA 2Q58A 4OMGA 4KFAA 3LGKA 5IMIA 2E91A 3KROA 3S9VA 4DHDA 3OABA 2AZJA 3V1VA 3LEEA 2E90A 4QPFA 4KVIA 4EA1A 3LGZB 2F9KF 3SDQA 4QXSF 3NPKA 2I19A 3V66A 5CG5A 3PYAA 5E8LA 3Q2ZA 4JYXA 2E8VA 2VF6A 3ASXA 4LTZA 4LLTA 3ZOUA 3AQ0A 5DGMF 3WCLA 4RXAA 3CKEA 4L2XF 3N5JF 2E92A 1WL1A 3P5RA 4LFVF 3LMDA 3ZMCA 5CG6A 1YYSA 5HN7A 5ILYA 5IVGA 1DGPA 2ZY1A 3WCIA 3TFPA 4MC8A 5IKHA 3APZA 1V4JA 3ACWA 4P0XA 2FTZA 3ICNA 5DIQF 4KUXA 4LZ0A 5EROA 1DI1A 5IK9A 1YYTA 3ICZA 3ZL6A 3KRFA 4E9UA 4NUAA 1ZW5A 3OACB 3W7FA 5IL3A 3M01A 4N9UA 3WCDA 3RYEA 4P0WA 3VJCA 3WSBA 2QISA 1N22A 1VG7A 3M9UA 5JV0F 4PVXF 3ID0A 3VJ9A 5B0KA 4FJQA 4OKZA 3M02A 1HM7A 1YHMA 3MZVA 4RXCA 2Q9YA 5B0LA 3WJOA 4LFEA 5EASA 4E1EA 3DYHA 5IMNA 4RXDA 2PS6A 5ILHA 4WK5A 2PS5A 3WC9A 4MC0A 3SDTA 5H9DA 3V1XA 4JVJF 3N3DA 3WE9A 4F6VA 5ILKA 5ERNA 3ADZA 3P5PA 3AE0A 3LZ9A 4NFJF 4LFGA 3IBAA 3SDUA 5IKAA 3RBMA 3KBKA 5KSXF 2F94F 3NPRA 3CP6A 4EA0A 5HNAA 2E4OA 5EAUA 2ZCRA 3KROB 4F6XA 1WL2A 4LLSA 1FPSA 3OABB 4KPJA 4ZQ8A 1EZFA 4KVDA 2ZCOA 4LA5A 3KRCA 3KRAA 3SAEA 3WJNA 3LLWA 4GP1A 1WMWA 3LJIA 3NF2A 4KQ5A 3BNXA 2P1CA 4LOBA 1RTRA 3LSNA 5ER8A 5B02A 5AYPA 4NFIF 4P0VA 2F8CF 2F7MF 1UBYA 2ZCSA 2Z7IA 5IMPA 4H5EF 1YYQA 1N23A 3EFQA 2Z4VA 5A0KA 2Z52A 3VJDA 4DI5A 3M00A 2J5CA 3VJBA 1VG6A 2E93A 5AHUB 3P8LA 3Q2QA 2EWGA 4GP2A 3LDWA 2Z4YA 1HXCA 4LPGF 3UCAA 3ACXA 4XQRF 1YQ7A 5DHKA 2Z4XA 5ILJA 4DXJA 1YV5A 2Z4ZA 3KRFB 3QKCA 3WEHA 3SDRA 3IPIA 4KQUA 4K10A 5IK0A 3VJ8A 5B0MA 3ICKA 3BNYA 3KRPA 5HN9A 3TC1A 2PS7A 4RNQA 2ONGA 5DGNF 4MC3A 5JA0F 3TS7A 4DZWA 2ZEVA 4F62A 3Q1OA 3AQCB 3WCBA 5A0JA 3WCHA 3N49F 3PYBA 5AFXA 5IL8A 3TFVA 3N46F 4KPDA 3P8RA 2J1PA 2OA6A 3KB9A 4JXNA 3ICMA 4NKFA 5HN8A 3P41A 3WSAA 2Q80A 4NFKF 1HM4A 3WCCA 5DW7A 3N3LF 3M0GA 5JV2F 5E8HA 1UBXA 3N6KF 4NKEA 5DJPF 4OKMA 3N0GA 5E8KA 3EGTA 4EA2A 4DWBA 1WKZA 3WCGA 4JZBA 1PS1A 5C05A 2ZEUA 2Q9ZA 2FORA 2E95A 5DZ2A 4KKMA 1HX9A 5JV1F 4OMHA 3DYGA 2DH4A 2AZKA 1HXGA 4N1ZF 2E8WA 4FP4A 4GAXA 2E8TA 1N1ZA 4JXYA 2F8ZF 3LOMA 2Z7HA 3RMGA 3QQVA 3N45F 3VJEA 3NRIA 2AEKA 2E8XA 4KVWA 5DGSF 5DJVF 3WEGA 4XQTF 2J1OA 1N20A 5B0JA 3WEJA 3S4JA 3KRAB 5B00A 5B03A 5ILZA 2ONHA 1YHLA 2F89F 5B01A 3WCMA 3ACYA 1WL0A 3LVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O1O A;  1UBW A;  4LIX A;  2OPM A;  3TFN A;  3WEK A;  1N21 A;  3SDV A;  1RQJ A;  1YYU A;  1YHK A;  2Z78 A;  4JZX A;  3VJA A;  3WCE A;  1V4K A;  3Q30 A;  4H5C F;  2PS8 A;  5IM1 A;  1YJ4 A;  2AET A;  3ZMB A;  2RAH A;  4UMJ A;  5I1U A;  4GA3 A;  5DHI A;  4LXW A;  4LA6 A;  3EZ3 A;  3N1W F;  4LZC A;  5IN8 A;  4H5D F;  1JFG A;  5ILD A;  4XQS F;  2Z50 A;  3PH7 A;  4E9Z A;  5IK6 A;  2H8O A;  3KRP B;  3AQB B;  5DJR F;  1KIZ A;  4OGU A;  1WL3 A;  4LZ3 A;  4KVY A;  2OPN A;  1JFA A;  1WY0 A;  4LPH F;  3G4F A;  2OGD A;  3OAC A;  2Z4W A;  1V4H A;  3B7L A;  3PDE A;  4HD1 A;  3WCA A;  3WEI A;  3N1V F;  3DYF A;  3G4D A;  3CC9 A;  5A0I A;  3MAV A;  5EAT A;  3LG5 A;  5ERM A;  1YYR A;  4RXE A;  5AEL A;  2PS4 A;  4NG6 A;  4LUU A;  2E94 A;  5B0I A;  1N24 A;  2E8U A;  1N1B A;  5JUZ F;  4PVY F;  2AEL A;  4DEM F;  1KIY A;  4KWD A;  3WCJ A;  1VG3 A;  3OYR A;  1VG4 A;  1RQI A;  1UBV A;  3ZCD A;  3LK5 A;  3WCF A;  3WJK A;  1VG2 A;  2F92 F;  4DWG A;  1HXA A;  4LTV A;  3WEF A;  4KQS A;  4RYP A;  2ZCQ A;  3KRC B;  4KK2 A;  3PKO A;  1V4I A;  3N0F A;  4Q23 A;  5ILI A;  3N5H F;  3RYW A;  2AZL A;  1V4E A;  2Q58 A;  4OMG A;  4KFA A;  3LGK A;  5IMI A;  2E91 A;  3KRO A;  3S9V A;  4DHD A;  3OAB A;  2AZJ A;  3V1V A;  3LEE A;  2E90 A;  4QPF A;  4KVI A;  4EA1 A;  3LGZ B;  2F9K F;  3SDQ A;  4QXS F;  3NPK A;  2I19 A;  3V66 A;  5CG5 A;  3PYA A;  5E8L A;  3Q2Z A;  4JYX A;  2E8V A;  2VF6 A;  3ASX A;  4LTZ A;  4LLT A;  3ZOU A;  3AQ0 A;  5DGM F;  3WCL A;  4RXA A;  3CKE A;  4L2X F;  3N5J F;  2E92 A;  1WL1 A;  3P5R A;  4LFV F;  3LMD A;  3ZMC A;  5CG6 A;  1YYS A;  5HN7 A;  5ILY A;  5IVG A;  1DGP A;  2ZY1 A;  3WCI A;  3TFP A;  4MC8 A;  5IKH A;  3APZ A;  1V4J A;  3ACW A;  4P0X A;  2FTZ A;  3ICN A;  5DIQ F;  4KUX A;  4LZ0 A;  5ERO A;  1DI1 A;  5IK9 A;  1YYT A;  3ICZ A;  3ZL6 A;  3KRF A;  4E9U A;  4NUA A;  1ZW5 A;  3OAC B;  3W7F A;  5IL3 A;  3M01 A;  4N9U A;  3WCD A;  3RYE A;  4P0W A;  3VJC A;  3WSB A;  2QIS A;  1N22 A;  1VG7 A;  3M9U A;  5JV0 F;  4PVX F;  3ID0 A;  3VJ9 A;  5B0K A;  4FJQ A;  4OKZ A;  3M02 A;  1HM7 A;  1YHM A;  3MZV A;  4RXC A;  2Q9Y A;  5B0L A;  3WJO A;  4LFE A;  5EAS A;  4E1E A;  3DYH A;  5IMN A;  4RXD A;  2PS6 A;  5ILH A;  4WK5 A;  2PS5 A;  3WC9 A;  4MC0 A;  3SDT A;  5H9D A;  3V1X A;  4JVJ F;  3N3D A;  3WE9 A;  4F6V A;  5ILK A;  5ERN A;  3ADZ A;  3P5P A;  3AE0 A;  3LZ9 A;  4NFJ F;  4LFG A;  3IBA A;  3SDU A;  5IKA A;  3RBM A;  3KBK A;  5KSX F;  2F94 F;  3NPR A;  3CP6 A;  4EA0 A;  5HNA A;  2E4O A;  5EAU A;  2ZCR A;  3KRO B;  4F6X A;  1WL2 A;  4LLS A;  1FPS A;  3OAB B;  4KPJ A;  4ZQ8 A;  1EZF A;  4KVD A;  2ZCO A;  4LA5 A;  3KRC A;  3KRA A;  3SAE A;  3WJN A;  3LLW A;  4GP1 A;  1WMW A;  3LJI A;  3NF2 A;  4KQ5 A;  3BNX A;  2P1C A;  4LOB A;  1RTR A;  3LSN A;  5ER8 A;  5B02 A;  5AYP A;  4NFI F;  4P0V A;  2F8C F;  2F7M F;  1UBY A;  2ZCS A;  2Z7I A;  5IMP A;  4H5E F;  1YYQ A;  1N23 A;  3EFQ A;  2Z4V A;  5A0K A;  2Z52 A;  3VJD A;  4DI5 A;  3M00 A;  2J5C A;  3VJB A;  1VG6 A;  2E93 A;  5AHU B;  3P8L A;  3Q2Q A;  2EWG A;  4GP2 A;  3LDW A;  2Z4Y A;  1HXC A;  4LPG F;  3UCA A;  3ACX A;  4XQR F;  1YQ7 A;  5DHK A;  2Z4X A;  5ILJ A;  4DXJ A;  1YV5 A;  2Z4Z A;  3KRF B;  3QKC A;  3WEH A;  3SDR A;  3IPI A;  4KQU A;  4K10 A;  5IK0 A;  3VJ8 A;  5B0M A;  3ICK A;  3BNY A;  3KRP A;  5HN9 A;  3TC1 A;  2PS7 A;  4RNQ A;  2ONG A;  5DGN F;  4MC3 A;  5JA0 F;  3TS7 A;  4DZW A;  2ZEV A;  4F62 A;  3Q1O A;  3AQC B;  3WCB A;  5A0J A;  3WCH A;  3N49 F;  3PYB A;  5AFX A;  5IL8 A;  3TFV A;  3N46 F;  4KPD A;  3P8R A;  2J1P A;  2OA6 A;  3KB9 A;  4JXN A;  3ICM A;  4NKF A;  5HN8 A;  3P41 A;  3WSA A;  2Q80 A;  4NFK F;  1HM4 A;  3WCC A;  5DW7 A;  3N3L F;  3M0G A;  5JV2 F;  5E8H A;  1UBX A;  3N6K F;  4NKE A;  5DJP F;  4OKM A;  3N0G A;  5E8K A;  3EGT A;  4EA2 A;  4DWB A;  1WKZ A;  3WCG A;  4JZB A;  1PS1 A;  5C05 A;  2ZEU A;  2Q9Z A;  2FOR A;  2E95 A;  5DZ2 A;  4KKM A;  1HX9 A;  5JV1 F;  4OMH A;  3DYG A;  2DH4 A;  2AZK A;  1HXG A;  4N1Z F;  2E8W A;  4FP4 A;  4GAX A;  2E8T A;  1N1Z A;  4JXY A;  2F8Z F;  3LOM A;  2Z7H A;  3RMG A;  3QQV A;  3N45 F;  3VJE A;  3NRI A;  2AEK A;  2E8X A;  4KVW A;  5DGS F;  5DJV F;  3WEG A;  4XQT F;  2J1O A;  1N20 A;  5B0J A;  3WEJ A;  3S4J A;  3KRA B;  5B00 A;  5B03 A;  5ILZ A;  2ONH A;  1YHL A;  2F89 F;  5B01 A;  3WCM A;  3ACY A;  1WL0 A;  3LVS A; 
#chains in the Genus database with same CATH topology
 2O1O A;  1UBW A;  4LIX A;  2OPM A;  3TFN A;  3WEK A;  1N21 A;  3SDV A;  1RQJ A;  1YYU A;  1YHK A;  2Z78 A;  4JZX A;  3VJA A;  3WCE A;  1V4K A;  3Q30 A;  4H5C F;  2PS8 A;  5IM1 A;  1YJ4 A;  2AET A;  3ZMB A;  2RAH A;  4UMJ A;  5I1U A;  4GA3 A;  5DHI A;  4LXW A;  4LA6 A;  3EZ3 A;  3N1W F;  4LZC A;  5IN8 A;  4H5D F;  1JFG A;  5ILD A;  4XQS F;  2Z50 A;  3PH7 A;  4E9Z A;  5IK6 A;  2H8O A;  3KRP B;  3AQB B;  5DJR F;  1KIZ A;  4OGU A;  1WL3 A;  4LZ3 A;  4KVY A;  2OPN A;  1JFA A;  1WY0 A;  4LPH F;  3G4F A;  2OGD A;  3OAC A;  2Z4W A;  1V4H A;  3B7L A;  3PDE A;  4HD1 A;  3WCA A;  3WEI A;  3N1V F;  3DYF A;  3G4D A;  3CC9 A;  5A0I A;  3MAV A;  5EAT A;  3LG5 A;  5ERM A;  1YYR A;  4RXE A;  5AEL A;  2PS4 A;  4NG6 A;  4LUU A;  2E94 A;  5B0I A;  1N24 A;  2E8U A;  1N1B A;  5JUZ F;  4PVY F;  2AEL A;  4DEM F;  1KIY A;  4KWD A;  3WCJ A;  1VG3 A;  3OYR A;  1VG4 A;  1RQI A;  1UBV A;  3ZCD A;  3LK5 A;  3WCF A;  3WJK A;  1VG2 A;  2F92 F;  4DWG A;  1HXA A;  4LTV A;  3WEF A;  4KQS A;  4RYP A;  2ZCQ A;  3KRC B;  4KK2 A;  3PKO A;  1V4I A;  3N0F A;  4Q23 A;  5ILI A;  3N5H F;  3RYW A;  2AZL A;  1V4E A;  2Q58 A;  4OMG A;  4KFA A;  3LGK A;  5IMI A;  2E91 A;  3KRO A;  3S9V A;  4DHD A;  3OAB A;  2AZJ A;  3V1V A;  3LEE A;  2E90 A;  4QPF A;  4KVI A;  4EA1 A;  3LGZ B;  2F9K F;  3SDQ A;  4QXS F;  3NPK A;  2I19 A;  3V66 A;  5CG5 A;  3PYA A;  5E8L A;  3Q2Z A;  4JYX A;  2E8V A;  2VF6 A;  3ASX A;  4LTZ A;  4LLT A;  3ZOU A;  3AQ0 A;  5DGM F;  3WCL A;  4RXA A;  3CKE A;  4L2X F;  3N5J F;  2E92 A;  1WL1 A;  3P5R A;  4LFV F;  3LMD A;  3ZMC A;  5CG6 A;  1YYS A;  5HN7 A;  5ILY A;  5IVG A;  1DGP A;  2ZY1 A;  3WCI A;  3TFP A;  4MC8 A;  5IKH A;  3APZ A;  1V4J A;  3ACW A;  4P0X A;  2FTZ A;  3ICN A;  5DIQ F;  4KUX A;  4LZ0 A;  5ERO A;  1DI1 A;  5IK9 A;  1YYT A;  3ICZ A;  3ZL6 A;  3KRF A;  4E9U A;  4NUA A;  1ZW5 A;  3OAC B;  3W7F A;  5IL3 A;  3M01 A;  4N9U A;  3WCD A;  3RYE A;  4P0W A;  3VJC A;  3WSB A;  2QIS A;  1N22 A;  1VG7 A;  3M9U A;  5JV0 F;  4PVX F;  3ID0 A;  3VJ9 A;  5B0K A;  4FJQ A;  4OKZ A;  3M02 A;  1HM7 A;  1YHM A;  3MZV A;  4RXC A;  2Q9Y A;  5B0L A;  3WJO A;  4LFE A;  5EAS A;  4E1E A;  3DYH A;  5IMN A;  4RXD A;  2PS6 A;  5ILH A;  4WK5 A;  2PS5 A;  3WC9 A;  4MC0 A;  3SDT A;  5H9D A;  3V1X A;  4JVJ F;  3N3D A;  3WE9 A;  4F6V A;  5ILK A;  5ERN A;  3ADZ A;  3P5P A;  3AE0 A;  3LZ9 A;  4NFJ F;  4LFG A;  3IBA A;  3SDU A;  5IKA A;  3RBM A;  3KBK A;  5KSX F;  2F94 F;  3NPR A;  3CP6 A;  4EA0 A;  5HNA A;  2E4O A;  5EAU A;  2ZCR A;  3KRO B;  4F6X A;  1WL2 A;  4LLS A;  1FPS A;  3OAB B;  4KPJ A;  4ZQ8 A;  1EZF A;  4KVD A;  2ZCO A;  4LA5 A;  3KRC A;  3KRA A;  3SAE A;  3WJN A;  3LLW A;  4GP1 A;  1WMW A;  3LJI A;  3NF2 A;  4KQ5 A;  3BNX A;  2P1C A;  4LOB A;  1RTR A;  3LSN A;  5ER8 A;  5B02 A;  5AYP A;  4NFI F;  4P0V A;  2F8C F;  2F7M F;  1UBY A;  2ZCS A;  2Z7I A;  5IMP A;  4H5E F;  1YYQ A;  1N23 A;  3EFQ A;  2Z4V A;  5A0K A;  2Z52 A;  3VJD A;  4DI5 A;  3M00 A;  2J5C A;  3VJB A;  1VG6 A;  2E93 A;  5AHU B;  3P8L A;  3Q2Q A;  2EWG A;  4GP2 A;  3LDW A;  2Z4Y A;  1HXC A;  4LPG F;  3UCA A;  3ACX A;  4XQR F;  1YQ7 A;  5DHK A;  2Z4X A;  5ILJ A;  4DXJ A;  1YV5 A;  2Z4Z A;  3KRF B;  3QKC A;  3WEH A;  3SDR A;  3IPI A;  4KQU A;  4K10 A;  5IK0 A;  3VJ8 A;  5B0M A;  3ICK A;  3BNY A;  3KRP A;  5HN9 A;  3TC1 A;  2PS7 A;  4RNQ A;  2ONG A;  5DGN F;  4MC3 A;  5JA0 F;  3TS7 A;  4DZW A;  2ZEV A;  4F62 A;  3Q1O A;  3AQC B;  3WCB A;  5A0J A;  3WCH A;  3N49 F;  3PYB A;  5AFX A;  5IL8 A;  3TFV A;  3N46 F;  4KPD A;  3P8R A;  2J1P A;  2OA6 A;  3KB9 A;  4JXN A;  3ICM A;  4NKF A;  5HN8 A;  3P41 A;  3WSA A;  2Q80 A;  4NFK F;  1HM4 A;  3WCC A;  5DW7 A;  3N3L F;  3M0G A;  5JV2 F;  5E8H A;  1UBX A;  3N6K F;  4NKE A;  5DJP F;  4OKM A;  3N0G A;  5E8K A;  3EGT A;  4EA2 A;  4DWB A;  1WKZ A;  3WCG A;  4JZB A;  1PS1 A;  5C05 A;  2ZEU A;  2Q9Z A;  2FOR A;  2E95 A;  5DZ2 A;  4KKM A;  1HX9 A;  5JV1 F;  4OMH A;  3DYG A;  2DH4 A;  2AZK A;  1HXG A;  4N1Z F;  2E8W A;  4FP4 A;  4GAX A;  2E8T A;  1N1Z A;  4JXY A;  2F8Z F;  3LOM A;  2Z7H A;  3RMG A;  3QQV A;  3N45 F;  3VJE A;  3NRI A;  2AEK A;  2E8X A;  4KVW A;  5DGS F;  5DJV F;  3WEG A;  4XQT F;  2J1O A;  1N20 A;  5B0J A;  3WEJ A;  3S4J A;  3KRA B;  5B00 A;  5B03 A;  5ILZ A;  2ONH A;  1YHL A;  2F89 F;  5B01 A;  3WCM A;  3ACY A;  1WL0 A;  3LVS A; 
#chains in the Genus database with same CATH homology
 2O1O A;  1UBW A;  4LIX A;  2OPM A;  3TFN A;  3WEK A;  1N21 A;  3SDV A;  1RQJ A;  1YYU A;  1YHK A;  2Z78 A;  4JZX A;  3VJA A;  3WCE A;  1V4K A;  3Q30 A;  4H5C F;  2PS8 A;  5IM1 A;  1YJ4 A;  2AET A;  3ZMB A;  2RAH A;  4UMJ A;  5I1U A;  4GA3 A;  5DHI A;  4LXW A;  4LA6 A;  3EZ3 A;  3N1W F;  4LZC A;  5IN8 A;  4H5D F;  1JFG A;  5ILD A;  4XQS F;  2Z50 A;  3PH7 A;  4E9Z A;  5IK6 A;  2H8O A;  3KRP B;  3AQB B;  5DJR F;  1KIZ A;  4OGU A;  1WL3 A;  4LZ3 A;  4KVY A;  2OPN A;  1JFA A;  1WY0 A;  4LPH F;  3G4F A;  2OGD A;  3OAC A;  2Z4W A;  1V4H A;  3B7L A;  3PDE A;  4HD1 A;  3WCA A;  3WEI A;  3N1V F;  3DYF A;  3G4D A;  3CC9 A;  5A0I A;  3MAV A;  5EAT A;  3LG5 A;  5ERM A;  1YYR A;  4RXE A;  5AEL A;  2PS4 A;  4NG6 A;  4LUU A;  2E94 A;  5B0I A;  1N24 A;  2E8U A;  1N1B A;  5JUZ F;  4PVY F;  2AEL A;  4DEM F;  1KIY A;  4KWD A;  3WCJ A;  1VG3 A;  3OYR A;  1VG4 A;  1RQI A;  1UBV A;  3ZCD A;  3LK5 A;  3WCF A;  3WJK A;  1VG2 A;  2F92 F;  4DWG A;  1HXA A;  4LTV A;  3WEF A;  4KQS A;  4RYP A;  2ZCQ A;  3KRC B;  4KK2 A;  3PKO A;  1V4I A;  3N0F A;  4Q23 A;  5ILI A;  3N5H F;  3RYW A;  2AZL A;  1V4E A;  2Q58 A;  4OMG A;  4KFA A;  3LGK A;  5IMI A;  2E91 A;  3KRO A;  3S9V A;  4DHD A;  3OAB A;  2AZJ A;  3V1V A;  3LEE A;  2E90 A;  4QPF A;  4KVI A;  4EA1 A;  3LGZ B;  2F9K F;  3SDQ A;  4QXS F;  3NPK A;  2I19 A;  3V66 A;  5CG5 A;  3PYA A;  5E8L A;  3Q2Z A;  4JYX A;  2E8V A;  2VF6 A;  3ASX A;  4LTZ A;  4LLT A;  3ZOU A;  3AQ0 A;  5DGM F;  3WCL A;  4RXA A;  3CKE A;  4L2X F;  3N5J F;  2E92 A;  1WL1 A;  3P5R A;  4LFV F;  3LMD A;  3ZMC A;  5CG6 A;  1YYS A;  5HN7 A;  5ILY A;  5IVG A;  1DGP A;  2ZY1 A;  3WCI A;  3TFP A;  4MC8 A;  5IKH A;  3APZ A;  1V4J A;  3ACW A;  4P0X A;  2FTZ A;  3ICN A;  5DIQ F;  4KUX A;  4LZ0 A;  5ERO A;  1DI1 A;  5IK9 A;  1YYT A;  3ICZ A;  3ZL6 A;  3KRF A;  4E9U A;  4NUA A;  1ZW5 A;  3OAC B;  3W7F A;  5IL3 A;  3M01 A;  4N9U A;  3WCD A;  3RYE A;  4P0W A;  3VJC A;  3WSB A;  2QIS A;  1N22 A;  1VG7 A;  3M9U A;  5JV0 F;  4PVX F;  3ID0 A;  3VJ9 A;  5B0K A;  4FJQ A;  4OKZ A;  3M02 A;  1HM7 A;  1YHM A;  3MZV A;  4RXC A;  2Q9Y A;  5B0L A;  3WJO A;  4LFE A;  5EAS A;  4E1E A;  3DYH A;  5IMN A;  4RXD A;  2PS6 A;  5ILH A;  4WK5 A;  2PS5 A;  3WC9 A;  4MC0 A;  3SDT A;  5H9D A;  3V1X A;  4JVJ F;  3N3D A;  3WE9 A;  4F6V A;  5ILK A;  5ERN A;  3ADZ A;  3P5P A;  3AE0 A;  3LZ9 A;  4NFJ F;  4LFG A;  3IBA A;  3SDU A;  5IKA A;  3RBM A;  3KBK A;  5KSX F;  2F94 F;  3NPR A;  3CP6 A;  4EA0 A;  5HNA A;  2E4O A;  5EAU A;  2ZCR A;  3KRO B;  4F6X A;  1WL2 A;  4LLS A;  1FPS A;  3OAB B;  4KPJ A;  4ZQ8 A;  1EZF A;  4KVD A;  2ZCO A;  4LA5 A;  3KRC A;  3KRA A;  3SAE A;  3WJN A;  3LLW A;  4GP1 A;  1WMW A;  3LJI A;  3NF2 A;  4KQ5 A;  3BNX A;  2P1C A;  4LOB A;  1RTR A;  3LSN A;  5ER8 A;  5B02 A;  5AYP A;  4NFI F;  4P0V A;  2F8C F;  2F7M F;  1UBY A;  2ZCS A;  2Z7I A;  5IMP A;  4H5E F;  1YYQ A;  1N23 A;  3EFQ A;  2Z4V A;  5A0K A;  2Z52 A;  3VJD A;  4DI5 A;  3M00 A;  2J5C A;  3VJB A;  1VG6 A;  2E93 A;  5AHU B;  3P8L A;  3Q2Q A;  2EWG A;  4GP2 A;  3LDW A;  2Z4Y A;  1HXC A;  4LPG F;  3UCA A;  3ACX A;  4XQR F;  1YQ7 A;  5DHK A;  2Z4X A;  5ILJ A;  4DXJ A;  1YV5 A;  2Z4Z A;  3KRF B;  3QKC A;  3WEH A;  3SDR A;  3IPI A;  4KQU A;  4K10 A;  5IK0 A;  3VJ8 A;  5B0M A;  3ICK A;  3BNY A;  3KRP A;  5HN9 A;  3TC1 A;  2PS7 A;  4RNQ A;  2ONG A;  5DGN F;  4MC3 A;  5JA0 F;  3TS7 A;  4DZW A;  2ZEV A;  4F62 A;  3Q1O A;  3AQC B;  3WCB A;  5A0J A;  3WCH A;  3N49 F;  3PYB A;  5AFX A;  5IL8 A;  3TFV A;  3N46 F;  4KPD A;  3P8R A;  2J1P A;  2OA6 A;  3KB9 A;  4JXN A;  3ICM A;  4NKF A;  5HN8 A;  3P41 A;  3WSA A;  2Q80 A;  4NFK F;  1HM4 A;  3WCC A;  5DW7 A;  3N3L F;  3M0G A;  5JV2 F;  5E8H A;  1UBX A;  3N6K F;  4NKE A;  5DJP F;  4OKM A;  3N0G A;  5E8K A;  3EGT A;  4EA2 A;  4DWB A;  1WKZ A;  3WCG A;  4JZB A;  1PS1 A;  5C05 A;  2ZEU A;  2Q9Z A;  2FOR A;  2E95 A;  5DZ2 A;  4KKM A;  1HX9 A;  5JV1 F;  4OMH A;  3DYG A;  2DH4 A;  2AZK A;  1HXG A;  4N1Z F;  2E8W A;  4FP4 A;  4GAX A;  2E8T A;  1N1Z A;  4JXY A;  2F8Z F;  3LOM A;  2Z7H A;  3RMG A;  3QQV A;  3N45 F;  3VJE A;  3NRI A;  2AEK A;  2E8X A;  4KVW A;  5DGS F;  5DJV F;  3WEG A;  4XQT F;  2J1O A;  1N20 A;  5B0J A;  3WEJ A;  3S4J A;  3KRA B;  5B00 A;  5B03 A;  5ILZ A;  2ONH A;  1YHL A;  2F89 F;  5B01 A;  3WCM A;  3ACY A;  1WL0 A;  3LVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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