2PS6A

N225d/s229t trichodiene synthase
Total Genus 152
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
352
structure length
352
Chain Sequence
NFPTEYFLNTTVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSKDDPYPTMVNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTLDFFEGCWIEQYNFGGFPGSHDYPQFLRRMNGLGHCVGASLWPKEQFNERSLFLEITSAIAQMENWMVWVDDLMTFYKEFDDERDQISLVKNYVVSDEISLHEALEKLTQDTLHSSKQMVAVFSDKDPQVMDTIECFMHGYVTWHLCDRRYRLSEIYEKVKEEKTEDAQKFCKFYEQAANVGAVSPSEWAYPPVAQLANV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords Trichodiene synthase
publication title Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif.
pubmed doi rcsb
source organism Fusarium sporotrichioides
total genus 152
structure length 352
sequence length 352
chains with identical sequence B
ec nomenclature ec 4.2.3.6: Trichodiene synthase.
pdb deposition date 2007-05-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06330 TRI5 Trichodiene synthase (TRI5)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2ps6A00
4JYXA 1RQJA 5DJVF 3TC1A 2ONHA 3TFNA 1UBXA 3ID0A 3CC9A 1EZFA 4LA6A 1JFAA 4QPFA 5IMIA 4JZBA 4LIXA 5E8LA 1YYRA 1VG3A 4LLTA 3VJAA 3QQVA 1UBVA 2OPNA 2OA6A 3LDWA 2E8UA 4H5CF 2E91A 2QISA 4H5DF 3AQCB 4EA1A 4QXSF 5IMPA 4JZXA 4DWBA 3CP6A 1YHLA 1V4JA 5EROA 1WL3A 3LJIA 4LPGF 5E8HA 1V4HA 2Z7HA 3LEEA 3WEJA 5ILJA 3LGKA 3QKCA 3NRIA 5IVGA 1V4IA 3LG5A 3OACB 4LFVF 3M9UA 3AQ0A 3WJNA 4P0WA 3M00A 3BNYA 3S4JA 4PVYF 4F62A 1YV5A 3EFQA 4LXWA 5B00A 5B03A 5B0KA 3TS7A 3Q1OA 3PDEA 4DWGA 5ILIA 3RMGA 2PS4A 3KRAA 4L2XF 3ADZA 3CKEA 5ILYA 3WJOA 5HN8A 4MC8A 2ONGA 1PS1A 3WJKA 1V4KA 4LTVA 1V4EA 5C05A 4LTZA 4XQSF 5AHUB 3LMDA 2ZCSA 4LPHF 1ZW5A 3PYAA 4OKMA 2I19A 3WC9A 5IL8A 3P5PA 2J1OA 1YYTA 2E90A 3G4FA 5DIQF 4RXEA 5AYPA 2VF6A 5IKHA 3RYEA 2ZCOA 5DGSF 3VJ8A 3WE9A 2Q80A 3KRCB 3V1XA 3P5RA 5DHKA 4P0VA 5JA0F 5IL3A 1YYQA 1N23A 3TFVA 3M0GA 5HN7A 3WCAA 3KBKA 3LOMA 3V1VA 5EATA 4P0XA 3Q2ZA 2Z52A 3OABA 5B01A 5IK9A 3LSNA 3VJ9A 3SDQA 1UBWA 2OPMA 4EA2A 3N45F 1N20A 2O1OA 2E92A 2DH4A 1RTRA 5ERMA 1WL1A 1VG7A 4N1ZF 5JV0F 5AELA 1KIYA 1N1ZA 1YQ7A 3VJEA 4DXJA 3KRPB 4DZWA 4KQ5A 3ASXA 4LZCA 3P41A 3KB9A 3UCAA 4UMJA 3N46F 4MC3A 4RNQA 3W7FA 2P1CA 3WCJA 3N1VF 2ZCRA 2F94F 4KK2A 3KRFA 3WSBA 3VJDA 1WY0A 3N6KF 2H8OA 3WCDA 3ICNA 4KFAA 3KRAB 5H9DA 3WEHA 1HXCA 4RYPA 1HX9A 3N5HF 3WCEA 3ICKA 4F6XA 4NUAA 4OMHA 4EA0A 3SAEA 3SDVA 3NPKA 2F8CF 2E8VA 4KPJA 3SDTA 1WKZA 3M01A 2Z50A 4GP2A 5HNAA 1YYUA 4RXAA 4NFJF 4LZ3A 4KQUA 3G4DA 5B0LA 5IN8A 4KUXA 4E9UA 3LVSA 3LK5A 4LA5A 2FTZA 3APZA 3ACWA 3RBMA 5JV2F 1DI1A 5B02A 3WCMA 4HD1A 4DI5A 4F6VA 2AEKA 5A0IA 3PH7A 1HM4A 1N24A 2PS5A 3DYFA 3ZL6A 2AETA 3ZMBA 5CG5A 1WL0A 4K10A 2E95A 1HM7A 5ER8A 2PS6A 3PYBA 3ZOUA 4LFEA 1HXAA 5AFXA 4KWDA 1UBYA 3OACA 4LUUA 5B0MA 4KVDA 3ZMCA 3MAVA 3NF2A 3WCBA 2RAHA 3Q30A 5A0JA 4NKEA 3MZVA 3Q2QA 3KROA 3IBAA 4E9ZA 4PVXF 5IKAA 4JXNA 1YHKA 3WEGA 3OYRA 3WCIA 1VG4A 2F8ZF 2AZJA 4N9UA 2ZCQA 3WSAA 3WEFA 2E8WA 2AELA 2Z7IA 3WCHA 3NPRA 5ILZA 3M02A 4ZQ8A 3S9VA 3SDRA 5B0IA 2ZEUA 3KRCA 3EZ3A 5DHIA 3AE0A 5CG6A 2F7MF 2F92F 5IMNA 4OGUA 5EASA 4XQTF 4FJQA 3LLWA 5EAUA 5JV1F 3IPIA 5JUZF 2PS7A 4RXCA 4JVJF 2ZY1A 3N0GA 1N21A 2EWGA 2E4OA 3ICMA 5DGMF 3VJBA 3DYGA 5E8KA 1N1BA 3ACYA 1N22A 3DYHA 4LLSA 3N49F 2Z78A 4FP4A 4NG6A 5I1UA 4E1EA 3WEKA 4NFKF 4GA3A 5IK0A 4NFIF 1DGPA 1KIZA 1HXGA 3KRPA 3PKOA 2E94A 2F9KF 5HN9A 5ILHA 5DJPF 5ILDA 3SDUA 3P8LA 4KQSA 4KVWA 2Z4VA 5DW7A 3OABB 3RYWA 5IM1A 3ACXA 3AQBB 2Q9YA 3TFPA 3KROB 3N3DA 4JXYA 4GAXA 4DHDA 3N0FA 3LGZB 1RQIA 3WCFA 4LOBA 2F89F 4DEMF 3WCCA 2Z4ZA 2AZKA 2E93A 1YYSA 5KSXF 1FPSA 5B0JA 3WEIA 3LZ9A 4OMGA 3ICZA 3WCGA 4GP1A 5IK6A 2Q58A 2ZEVA 2J5CA 1VG6A 3V66A 2Z4YA 5ERNA 3ZCDA 1YJ4A 3EGTA 2FORA 4OKZA 2PS8A 3BNXA 4RXDA 4H5EF 3KRFB 4XQRF 4LFGA 5A0KA 3VJCA 4MC0A 2E8XA 2AZLA 3N3LF 4LZ0A 5DGNF 1WMWA 4WK5A 5DZ2A 3P8RA 3B7LA 4Q23A 2Q9ZA 1WL2A 5ILKA 2Z4XA 4KVIA 2OGDA 2Z4WA 4KKMA 4KPDA 5DJRF 3WCLA 4NKFA 4KVYA 1YHMA 1VG2A 3N1WF 2E8TA 1JFGA 3N5JF 2J1PA
chains in the Genus database with same CATH superfamily
4JYXA 1RQJA 5DJVF 3TC1A 2ONHA 3TFNA 1UBXA 3ID0A 3CC9A 1EZFA 4LA6A 1JFAA 4QPFA 5IMIA 4JZBA 4LIXA 5E8LA 1YYRA 1VG3A 4LLTA 3VJAA 3QQVA 1UBVA 2OPNA 2OA6A 3LDWA 2E8UA 4H5CF 2E91A 2QISA 4H5DF 3AQCB 4EA1A 4QXSF 5IMPA 4JZXA 4DWBA 3CP6A 1YHLA 1V4JA 5EROA 1WL3A 3LJIA 4LPGF 5E8HA 1V4HA 2Z7HA 3LEEA 3WEJA 5ILJA 3LGKA 3QKCA 3NRIA 5IVGA 1V4IA 3LG5A 3OACB 4LFVF 3M9UA 3AQ0A 3WJNA 4P0WA 3M00A 3BNYA 3S4JA 4PVYF 4F62A 1YV5A 3EFQA 4LXWA 5B00A 5B03A 5B0KA 3TS7A 3Q1OA 3PDEA 4DWGA 5ILIA 3RMGA 2PS4A 3KRAA 4L2XF 3ADZA 3CKEA 5ILYA 3WJOA 5HN8A 4MC8A 2ONGA 1PS1A 3WJKA 1V4KA 4LTVA 1V4EA 5C05A 4LTZA 4XQSF 5AHUB 3LMDA 2ZCSA 4LPHF 1ZW5A 3PYAA 4OKMA 2I19A 3WC9A 5IL8A 3P5PA 2J1OA 1YYTA 2E90A 3G4FA 5DIQF 4RXEA 5AYPA 2VF6A 5IKHA 3RYEA 2ZCOA 5DGSF 3VJ8A 3WE9A 2Q80A 3KRCB 3V1XA 3P5RA 5DHKA 4P0VA 5JA0F 5IL3A 1YYQA 1N23A 3TFVA 3M0GA 5HN7A 3WCAA 3KBKA 3LOMA 3V1VA 5EATA 4P0XA 3Q2ZA 2Z52A 3OABA 5B01A 5IK9A 3LSNA 3VJ9A 3SDQA 1UBWA 2OPMA 4EA2A 3N45F 1N20A 2O1OA 2E92A 2DH4A 1RTRA 5ERMA 1WL1A 1VG7A 4N1ZF 5JV0F 5AELA 1KIYA 1N1ZA 1YQ7A 3VJEA 4DXJA 3KRPB 4DZWA 4KQ5A 3ASXA 4LZCA 3P41A 3KB9A 3UCAA 4UMJA 3N46F 4MC3A 4RNQA 3W7FA 2P1CA 3WCJA 3N1VF 2ZCRA 2F94F 4KK2A 3KRFA 3WSBA 3VJDA 1WY0A 3N6KF 2H8OA 3WCDA 3ICNA 4KFAA 3KRAB 5H9DA 3WEHA 1HXCA 4RYPA 1HX9A 3N5HF 3WCEA 3ICKA 4F6XA 4NUAA 4OMHA 4EA0A 3SAEA 3SDVA 3NPKA 2F8CF 2E8VA 4KPJA 3SDTA 1WKZA 3M01A 2Z50A 4GP2A 5HNAA 1YYUA 4RXAA 4NFJF 4LZ3A 4KQUA 3G4DA 5B0LA 5IN8A 4KUXA 4E9UA 3LVSA 3LK5A 4LA5A 2FTZA 3APZA 3ACWA 3RBMA 5JV2F 1DI1A 5B02A 3WCMA 4HD1A 4DI5A 4F6VA 2AEKA 5A0IA 3PH7A 1HM4A 1N24A 2PS5A 3DYFA 3ZL6A 2AETA 3ZMBA 5CG5A 1WL0A 4K10A 2E95A 1HM7A 5ER8A 2PS6A 3PYBA 3ZOUA 4LFEA 1HXAA 5AFXA 4KWDA 1UBYA 3OACA 4LUUA 5B0MA 4KVDA 3ZMCA 3MAVA 3NF2A 3WCBA 2RAHA 3Q30A 5A0JA 4NKEA 3MZVA 3Q2QA 3KROA 3IBAA 4E9ZA 4PVXF 5IKAA 4JXNA 1YHKA 3WEGA 3OYRA 3WCIA 1VG4A 2F8ZF 2AZJA 4N9UA 2ZCQA 3WSAA 3WEFA 2E8WA 2AELA 2Z7IA 3WCHA 3NPRA 5ILZA 3M02A 4ZQ8A 3S9VA 3SDRA 5B0IA 2ZEUA 3KRCA 3EZ3A 5DHIA 3AE0A 5CG6A 2F7MF 2F92F 5IMNA 4OGUA 5EASA 4XQTF 4FJQA 3LLWA 5EAUA 5JV1F 3IPIA 5JUZF 2PS7A 4RXCA 4JVJF 2ZY1A 3N0GA 1N21A 2EWGA 2E4OA 3ICMA 5DGMF 3VJBA 3DYGA 5E8KA 1N1BA 3ACYA 1N22A 3DYHA 4LLSA 3N49F 2Z78A 4FP4A 4NG6A 5I1UA 4E1EA 3WEKA 4NFKF 4GA3A 5IK0A 4NFIF 1DGPA 1KIZA 1HXGA 3KRPA 3PKOA 2E94A 2F9KF 5HN9A 5ILHA 5DJPF 5ILDA 3SDUA 3P8LA 4KQSA 4KVWA 2Z4VA 5DW7A 3OABB 3RYWA 5IM1A 3ACXA 3AQBB 2Q9YA 3TFPA 3KROB 3N3DA 4JXYA 4GAXA 4DHDA 3N0FA 3LGZB 1RQIA 3WCFA 4LOBA 2F89F 4DEMF 3WCCA 2Z4ZA 2AZKA 2E93A 1YYSA 5KSXF 1FPSA 5B0JA 3WEIA 3LZ9A 4OMGA 3ICZA 3WCGA 4GP1A 5IK6A 2Q58A 2ZEVA 2J5CA 1VG6A 3V66A 2Z4YA 5ERNA 3ZCDA 1YJ4A 3EGTA 2FORA 4OKZA 2PS8A 3BNXA 4RXDA 4H5EF 3KRFB 4XQRF 4LFGA 5A0KA 3VJCA 4MC0A 2E8XA 2AZLA 3N3LF 4LZ0A 5DGNF 1WMWA 4WK5A 5DZ2A 3P8RA 3B7LA 4Q23A 2Q9ZA 1WL2A 5ILKA 2Z4XA 4KVIA 2OGDA 2Z4WA 4KKMA 4KPDA 5DJRF 3WCLA 4NKFA 4KVYA 1YHMA 1VG2A 3N1WF 2E8TA 1JFGA 3N5JF 2J1PA
chains in the Genus database with same CATH topology
4JYXA 1RQJA 5DJVF 3TC1A 2ONHA 3TFNA 1UBXA 3ID0A 3CC9A 1EZFA 4LA6A 1JFAA 4QPFA 5IMIA 4JZBA 4LIXA 5E8LA 1YYRA 1VG3A 4LLTA 3VJAA 3QQVA 1UBVA 2OPNA 2OA6A 3LDWA 2E8UA 4H5CF 2E91A 2QISA 4H5DF 3AQCB 4EA1A 4QXSF 5IMPA 4JZXA 4DWBA 3CP6A 1YHLA 1V4JA 5EROA 1WL3A 3LJIA 4LPGF 5E8HA 1V4HA 2Z7HA 3LEEA 3WEJA 5ILJA 3LGKA 3QKCA 3NRIA 5IVGA 1V4IA 3LG5A 3OACB 4LFVF 3M9UA 3AQ0A 3WJNA 4P0WA 3M00A 3BNYA 3S4JA 4PVYF 4F62A 1YV5A 3EFQA 4LXWA 5B00A 5B03A 5B0KA 3TS7A 3Q1OA 3PDEA 4DWGA 5ILIA 3RMGA 2PS4A 3KRAA 4L2XF 3ADZA 3CKEA 5ILYA 3WJOA 5HN8A 4MC8A 2ONGA 1PS1A 3WJKA 1V4KA 4LTVA 1V4EA 5C05A 4LTZA 4XQSF 5AHUB 3LMDA 2ZCSA 4LPHF 1ZW5A 3PYAA 4OKMA 2I19A 3WC9A 5IL8A 3P5PA 2J1OA 1YYTA 2E90A 3G4FA 5DIQF 4RXEA 5AYPA 2VF6A 5IKHA 3RYEA 2ZCOA 5DGSF 3VJ8A 3WE9A 2Q80A 3KRCB 3V1XA 3P5RA 5DHKA 4P0VA 5JA0F 5IL3A 1YYQA 1N23A 3TFVA 3M0GA 5HN7A 3WCAA 3KBKA 3LOMA 3V1VA 5EATA 4P0XA 3Q2ZA 2Z52A 3OABA 5B01A 5IK9A 3LSNA 3VJ9A 3SDQA 1UBWA 2OPMA 4EA2A 3N45F 1N20A 2O1OA 2E92A 2DH4A 1RTRA 5ERMA 1WL1A 1VG7A 4N1ZF 5JV0F 5AELA 1KIYA 1N1ZA 1YQ7A 3VJEA 4DXJA 3KRPB 4DZWA 4KQ5A 3ASXA 4LZCA 3P41A 3KB9A 3UCAA 4UMJA 3N46F 4MC3A 4RNQA 3W7FA 2P1CA 3WCJA 3N1VF 2ZCRA 2F94F 4KK2A 3KRFA 3WSBA 3VJDA 1WY0A 3N6KF 2H8OA 3WCDA 3ICNA 4KFAA 3KRAB 5H9DA 3WEHA 1HXCA 4RYPA 1HX9A 3N5HF 3WCEA 3ICKA 4F6XA 4NUAA 4OMHA 4EA0A 3SAEA 3SDVA 3NPKA 2F8CF 2E8VA 4KPJA 3SDTA 1WKZA 3M01A 2Z50A 4GP2A 5HNAA 1YYUA 4RXAA 4NFJF 4LZ3A 4KQUA 3G4DA 5B0LA 5IN8A 4KUXA 4E9UA 3LVSA 3LK5A 4LA5A 2FTZA 3APZA 3ACWA 3RBMA 5JV2F 1DI1A 5B02A 3WCMA 4HD1A 4DI5A 4F6VA 2AEKA 5A0IA 3PH7A 1HM4A 1N24A 2PS5A 3DYFA 3ZL6A 2AETA 3ZMBA 5CG5A 1WL0A 4K10A 2E95A 1HM7A 5ER8A 2PS6A 3PYBA 3ZOUA 4LFEA 1HXAA 5AFXA 4KWDA 1UBYA 3OACA 4LUUA 5B0MA 4KVDA 3ZMCA 3MAVA 3NF2A 3WCBA 2RAHA 3Q30A 5A0JA 4NKEA 3MZVA 3Q2QA 3KROA 3IBAA 4E9ZA 4PVXF 5IKAA 4JXNA 1YHKA 3WEGA 3OYRA 3WCIA 1VG4A 2F8ZF 2AZJA 4N9UA 2ZCQA 3WSAA 3WEFA 2E8WA 2AELA 2Z7IA 3WCHA 3NPRA 5ILZA 3M02A 4ZQ8A 3S9VA 3SDRA 5B0IA 2ZEUA 3KRCA 3EZ3A 5DHIA 3AE0A 5CG6A 2F7MF 2F92F 5IMNA 4OGUA 5EASA 4XQTF 4FJQA 3LLWA 5EAUA 5JV1F 3IPIA 5JUZF 2PS7A 4RXCA 4JVJF 2ZY1A 3N0GA 1N21A 2EWGA 2E4OA 3ICMA 5DGMF 3VJBA 3DYGA 5E8KA 1N1BA 3ACYA 1N22A 3DYHA 4LLSA 3N49F 2Z78A 4FP4A 4NG6A 5I1UA 4E1EA 3WEKA 4NFKF 4GA3A 5IK0A 4NFIF 1DGPA 1KIZA 1HXGA 3KRPA 3PKOA 2E94A 2F9KF 5HN9A 5ILHA 5DJPF 5ILDA 3SDUA 3P8LA 4KQSA 4KVWA 2Z4VA 5DW7A 3OABB 3RYWA 5IM1A 3ACXA 3AQBB 2Q9YA 3TFPA 3KROB 3N3DA 4JXYA 4GAXA 4DHDA 3N0FA 3LGZB 1RQIA 3WCFA 4LOBA 2F89F 4DEMF 3WCCA 2Z4ZA 2AZKA 2E93A 1YYSA 5KSXF 1FPSA 5B0JA 3WEIA 3LZ9A 4OMGA 3ICZA 3WCGA 4GP1A 5IK6A 2Q58A 2ZEVA 2J5CA 1VG6A 3V66A 2Z4YA 5ERNA 3ZCDA 1YJ4A 3EGTA 2FORA 4OKZA 2PS8A 3BNXA 4RXDA 4H5EF 3KRFB 4XQRF 4LFGA 5A0KA 3VJCA 4MC0A 2E8XA 2AZLA 3N3LF 4LZ0A 5DGNF 1WMWA 4WK5A 5DZ2A 3P8RA 3B7LA 4Q23A 2Q9ZA 1WL2A 5ILKA 2Z4XA 4KVIA 2OGDA 2Z4WA 4KKMA 4KPDA 5DJRF 3WCLA 4NKFA 4KVYA 1YHMA 1VG2A 3N1WF 2E8TA 1JFGA 3N5JF 2J1PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JYX A;  1RQJ A;  5DJV F;  3TC1 A;  2ONH A;  3TFN A;  1UBX A;  3ID0 A;  3CC9 A;  1EZF A;  4LA6 A;  1JFA A;  4QPF A;  5IMI A;  4JZB A;  4LIX A;  5E8L A;  1YYR A;  1VG3 A;  4LLT A;  3VJA A;  3QQV A;  1UBV A;  2OPN A;  2OA6 A;  3LDW A;  2E8U A;  4H5C F;  2E91 A;  2QIS A;  4H5D F;  3AQC B;  4EA1 A;  4QXS F;  5IMP A;  4JZX A;  4DWB A;  3CP6 A;  1YHL A;  1V4J A;  5ERO A;  1WL3 A;  3LJI A;  4LPG F;  5E8H A;  1V4H A;  2Z7H A;  3LEE A;  3WEJ A;  5ILJ A;  3LGK A;  3QKC A;  3NRI A;  5IVG A;  1V4I A;  3LG5 A;  3OAC B;  4LFV F;  3M9U A;  3AQ0 A;  3WJN A;  4P0W A;  3M00 A;  3BNY A;  3S4J A;  4PVY F;  4F62 A;  1YV5 A;  3EFQ A;  4LXW A;  5B00 A;  5B03 A;  5B0K A;  3TS7 A;  3Q1O A;  3PDE A;  4DWG A;  5ILI A;  3RMG A;  2PS4 A;  3KRA A;  4L2X F;  3ADZ A;  3CKE A;  5ILY A;  3WJO A;  5HN8 A;  4MC8 A;  2ONG A;  1PS1 A;  3WJK A;  1V4K A;  4LTV A;  1V4E A;  5C05 A;  4LTZ A;  4XQS F;  5AHU B;  3LMD A;  2ZCS A;  4LPH F;  1ZW5 A;  3PYA A;  4OKM A;  2I19 A;  3WC9 A;  5IL8 A;  3P5P A;  2J1O A;  1YYT A;  2E90 A;  3G4F A;  5DIQ F;  4RXE A;  5AYP A;  2VF6 A;  5IKH A;  3RYE A;  2ZCO A;  5DGS F;  3VJ8 A;  3WE9 A;  2Q80 A;  3KRC B;  3V1X A;  3P5R A;  5DHK A;  4P0V A;  5JA0 F;  5IL3 A;  1YYQ A;  1N23 A;  3TFV A;  3M0G A;  5HN7 A;  3WCA A;  3KBK A;  3LOM A;  3V1V A;  5EAT A;  4P0X A;  3Q2Z A;  2Z52 A;  3OAB A;  5B01 A;  5IK9 A;  3LSN A;  3VJ9 A;  3SDQ A;  1UBW A;  2OPM A;  4EA2 A;  3N45 F;  1N20 A;  2O1O A;  2E92 A;  2DH4 A;  1RTR A;  5ERM A;  1WL1 A;  1VG7 A;  4N1Z F;  5JV0 F;  5AEL A;  1KIY A;  1N1Z A;  1YQ7 A;  3VJE A;  4DXJ A;  3KRP B;  4DZW A;  4KQ5 A;  3ASX A;  4LZC A;  3P41 A;  3KB9 A;  3UCA A;  4UMJ A;  3N46 F;  4MC3 A;  4RNQ A;  3W7F A;  2P1C A;  3WCJ A;  3N1V F;  2ZCR A;  2F94 F;  4KK2 A;  3KRF A;  3WSB A;  3VJD A;  1WY0 A;  3N6K F;  2H8O A;  3WCD A;  3ICN A;  4KFA A;  3KRA B;  5H9D A;  3WEH A;  1HXC A;  4RYP A;  1HX9 A;  3N5H F;  3WCE A;  3ICK A;  4F6X A;  4NUA A;  4OMH A;  4EA0 A;  3SAE A;  3SDV A;  3NPK A;  2F8C F;  2E8V A;  4KPJ A;  3SDT A;  1WKZ A;  3M01 A;  2Z50 A;  4GP2 A;  5HNA A;  1YYU A;  4RXA A;  4NFJ F;  4LZ3 A;  4KQU A;  3G4D A;  5B0L A;  5IN8 A;  4KUX A;  4E9U A;  3LVS A;  3LK5 A;  4LA5 A;  2FTZ A;  3APZ A;  3ACW A;  3RBM A;  5JV2 F;  1DI1 A;  5B02 A;  3WCM A;  4HD1 A;  4DI5 A;  4F6V A;  2AEK A;  5A0I A;  3PH7 A;  1HM4 A;  1N24 A;  2PS5 A;  3DYF A;  3ZL6 A;  2AET A;  3ZMB A;  5CG5 A;  1WL0 A;  4K10 A;  2E95 A;  1HM7 A;  5ER8 A;  2PS6 A;  3PYB A;  3ZOU A;  4LFE A;  1HXA A;  5AFX A;  4KWD A;  1UBY A;  3OAC A;  4LUU A;  5B0M A;  4KVD A;  3ZMC A;  3MAV A;  3NF2 A;  3WCB A;  2RAH A;  3Q30 A;  5A0J A;  4NKE A;  3MZV A;  3Q2Q A;  3KRO A;  3IBA A;  4E9Z A;  4PVX F;  5IKA A;  4JXN A;  1YHK A;  3WEG A;  3OYR A;  3WCI A;  1VG4 A;  2F8Z F;  2AZJ A;  4N9U A;  2ZCQ A;  3WSA A;  3WEF A;  2E8W A;  2AEL A;  2Z7I A;  3WCH A;  3NPR A;  5ILZ A;  3M02 A;  4ZQ8 A;  3S9V A;  3SDR A;  5B0I A;  2ZEU A;  3KRC A;  3EZ3 A;  5DHI A;  3AE0 A;  5CG6 A;  2F7M F;  2F92 F;  5IMN A;  4OGU A;  5EAS A;  4XQT F;  4FJQ A;  3LLW A;  5EAU A;  5JV1 F;  3IPI A;  5JUZ F;  2PS7 A;  4RXC A;  4JVJ F;  2ZY1 A;  3N0G A;  1N21 A;  2EWG A;  2E4O A;  3ICM A;  5DGM F;  3VJB A;  3DYG A;  5E8K A;  1N1B A;  3ACY A;  1N22 A;  3DYH A;  4LLS A;  3N49 F;  2Z78 A;  4FP4 A;  4NG6 A;  5I1U A;  4E1E A;  3WEK A;  4NFK F;  4GA3 A;  5IK0 A;  4NFI F;  1DGP A;  1KIZ A;  1HXG A;  3KRP A;  3PKO A;  2E94 A;  2F9K F;  5HN9 A;  5ILH A;  5DJP F;  5ILD A;  3SDU A;  3P8L A;  4KQS A;  4KVW A;  2Z4V A;  5DW7 A;  3OAB B;  3RYW A;  5IM1 A;  3ACX A;  3AQB B;  2Q9Y A;  3TFP A;  3KRO B;  3N3D A;  4JXY A;  4GAX A;  4DHD A;  3N0F A;  3LGZ B;  1RQI A;  3WCF A;  4LOB A;  2F89 F;  4DEM F;  3WCC A;  2Z4Z A;  2AZK A;  2E93 A;  1YYS A;  5KSX F;  1FPS A;  5B0J A;  3WEI A;  3LZ9 A;  4OMG A;  3ICZ A;  3WCG A;  4GP1 A;  5IK6 A;  2Q58 A;  2ZEV A;  2J5C A;  1VG6 A;  3V66 A;  2Z4Y A;  5ERN A;  3ZCD A;  1YJ4 A;  3EGT A;  2FOR A;  4OKZ A;  2PS8 A;  3BNX A;  4RXD A;  4H5E F;  3KRF B;  4XQR F;  4LFG A;  5A0K A;  3VJC A;  4MC0 A;  2E8X A;  2AZL A;  3N3L F;  4LZ0 A;  5DGN F;  1WMW A;  4WK5 A;  5DZ2 A;  3P8R A;  3B7L A;  4Q23 A;  2Q9Z A;  1WL2 A;  5ILK A;  2Z4X A;  4KVI A;  2OGD A;  2Z4W A;  4KKM A;  4KPD A;  5DJR F;  3WCL A;  4NKF A;  4KVY A;  1YHM A;  1VG2 A;  3N1W F;  2E8T A;  1JFG A;  3N5J F;  2J1P A; 
#chains in the Genus database with same CATH topology
 4JYX A;  1RQJ A;  5DJV F;  3TC1 A;  2ONH A;  3TFN A;  1UBX A;  3ID0 A;  3CC9 A;  1EZF A;  4LA6 A;  1JFA A;  4QPF A;  5IMI A;  4JZB A;  4LIX A;  5E8L A;  1YYR A;  1VG3 A;  4LLT A;  3VJA A;  3QQV A;  1UBV A;  2OPN A;  2OA6 A;  3LDW A;  2E8U A;  4H5C F;  2E91 A;  2QIS A;  4H5D F;  3AQC B;  4EA1 A;  4QXS F;  5IMP A;  4JZX A;  4DWB A;  3CP6 A;  1YHL A;  1V4J A;  5ERO A;  1WL3 A;  3LJI A;  4LPG F;  5E8H A;  1V4H A;  2Z7H A;  3LEE A;  3WEJ A;  5ILJ A;  3LGK A;  3QKC A;  3NRI A;  5IVG A;  1V4I A;  3LG5 A;  3OAC B;  4LFV F;  3M9U A;  3AQ0 A;  3WJN A;  4P0W A;  3M00 A;  3BNY A;  3S4J A;  4PVY F;  4F62 A;  1YV5 A;  3EFQ A;  4LXW A;  5B00 A;  5B03 A;  5B0K A;  3TS7 A;  3Q1O A;  3PDE A;  4DWG A;  5ILI A;  3RMG A;  2PS4 A;  3KRA A;  4L2X F;  3ADZ A;  3CKE A;  5ILY A;  3WJO A;  5HN8 A;  4MC8 A;  2ONG A;  1PS1 A;  3WJK A;  1V4K A;  4LTV A;  1V4E A;  5C05 A;  4LTZ A;  4XQS F;  5AHU B;  3LMD A;  2ZCS A;  4LPH F;  1ZW5 A;  3PYA A;  4OKM A;  2I19 A;  3WC9 A;  5IL8 A;  3P5P A;  2J1O A;  1YYT A;  2E90 A;  3G4F A;  5DIQ F;  4RXE A;  5AYP A;  2VF6 A;  5IKH A;  3RYE A;  2ZCO A;  5DGS F;  3VJ8 A;  3WE9 A;  2Q80 A;  3KRC B;  3V1X A;  3P5R A;  5DHK A;  4P0V A;  5JA0 F;  5IL3 A;  1YYQ A;  1N23 A;  3TFV A;  3M0G A;  5HN7 A;  3WCA A;  3KBK A;  3LOM A;  3V1V A;  5EAT A;  4P0X A;  3Q2Z A;  2Z52 A;  3OAB A;  5B01 A;  5IK9 A;  3LSN A;  3VJ9 A;  3SDQ A;  1UBW A;  2OPM A;  4EA2 A;  3N45 F;  1N20 A;  2O1O A;  2E92 A;  2DH4 A;  1RTR A;  5ERM A;  1WL1 A;  1VG7 A;  4N1Z F;  5JV0 F;  5AEL A;  1KIY A;  1N1Z A;  1YQ7 A;  3VJE A;  4DXJ A;  3KRP B;  4DZW A;  4KQ5 A;  3ASX A;  4LZC A;  3P41 A;  3KB9 A;  3UCA A;  4UMJ A;  3N46 F;  4MC3 A;  4RNQ A;  3W7F A;  2P1C A;  3WCJ A;  3N1V F;  2ZCR A;  2F94 F;  4KK2 A;  3KRF A;  3WSB A;  3VJD A;  1WY0 A;  3N6K F;  2H8O A;  3WCD A;  3ICN A;  4KFA A;  3KRA B;  5H9D A;  3WEH A;  1HXC A;  4RYP A;  1HX9 A;  3N5H F;  3WCE A;  3ICK A;  4F6X A;  4NUA A;  4OMH A;  4EA0 A;  3SAE A;  3SDV A;  3NPK A;  2F8C F;  2E8V A;  4KPJ A;  3SDT A;  1WKZ A;  3M01 A;  2Z50 A;  4GP2 A;  5HNA A;  1YYU A;  4RXA A;  4NFJ F;  4LZ3 A;  4KQU A;  3G4D A;  5B0L A;  5IN8 A;  4KUX A;  4E9U A;  3LVS A;  3LK5 A;  4LA5 A;  2FTZ A;  3APZ A;  3ACW A;  3RBM A;  5JV2 F;  1DI1 A;  5B02 A;  3WCM A;  4HD1 A;  4DI5 A;  4F6V A;  2AEK A;  5A0I A;  3PH7 A;  1HM4 A;  1N24 A;  2PS5 A;  3DYF A;  3ZL6 A;  2AET A;  3ZMB A;  5CG5 A;  1WL0 A;  4K10 A;  2E95 A;  1HM7 A;  5ER8 A;  2PS6 A;  3PYB A;  3ZOU A;  4LFE A;  1HXA A;  5AFX A;  4KWD A;  1UBY A;  3OAC A;  4LUU A;  5B0M A;  4KVD A;  3ZMC A;  3MAV A;  3NF2 A;  3WCB A;  2RAH A;  3Q30 A;  5A0J A;  4NKE A;  3MZV A;  3Q2Q A;  3KRO A;  3IBA A;  4E9Z A;  4PVX F;  5IKA A;  4JXN A;  1YHK A;  3WEG A;  3OYR A;  3WCI A;  1VG4 A;  2F8Z F;  2AZJ A;  4N9U A;  2ZCQ A;  3WSA A;  3WEF A;  2E8W A;  2AEL A;  2Z7I A;  3WCH A;  3NPR A;  5ILZ A;  3M02 A;  4ZQ8 A;  3S9V A;  3SDR A;  5B0I A;  2ZEU A;  3KRC A;  3EZ3 A;  5DHI A;  3AE0 A;  5CG6 A;  2F7M F;  2F92 F;  5IMN A;  4OGU A;  5EAS A;  4XQT F;  4FJQ A;  3LLW A;  5EAU A;  5JV1 F;  3IPI A;  5JUZ F;  2PS7 A;  4RXC A;  4JVJ F;  2ZY1 A;  3N0G A;  1N21 A;  2EWG A;  2E4O A;  3ICM A;  5DGM F;  3VJB A;  3DYG A;  5E8K A;  1N1B A;  3ACY A;  1N22 A;  3DYH A;  4LLS A;  3N49 F;  2Z78 A;  4FP4 A;  4NG6 A;  5I1U A;  4E1E A;  3WEK A;  4NFK F;  4GA3 A;  5IK0 A;  4NFI F;  1DGP A;  1KIZ A;  1HXG A;  3KRP A;  3PKO A;  2E94 A;  2F9K F;  5HN9 A;  5ILH A;  5DJP F;  5ILD A;  3SDU A;  3P8L A;  4KQS A;  4KVW A;  2Z4V A;  5DW7 A;  3OAB B;  3RYW A;  5IM1 A;  3ACX A;  3AQB B;  2Q9Y A;  3TFP A;  3KRO B;  3N3D A;  4JXY A;  4GAX A;  4DHD A;  3N0F A;  3LGZ B;  1RQI A;  3WCF A;  4LOB A;  2F89 F;  4DEM F;  3WCC A;  2Z4Z A;  2AZK A;  2E93 A;  1YYS A;  5KSX F;  1FPS A;  5B0J A;  3WEI A;  3LZ9 A;  4OMG A;  3ICZ A;  3WCG A;  4GP1 A;  5IK6 A;  2Q58 A;  2ZEV A;  2J5C A;  1VG6 A;  3V66 A;  2Z4Y A;  5ERN A;  3ZCD A;  1YJ4 A;  3EGT A;  2FOR A;  4OKZ A;  2PS8 A;  3BNX A;  4RXD A;  4H5E F;  3KRF B;  4XQR F;  4LFG A;  5A0K A;  3VJC A;  4MC0 A;  2E8X A;  2AZL A;  3N3L F;  4LZ0 A;  5DGN F;  1WMW A;  4WK5 A;  5DZ2 A;  3P8R A;  3B7L A;  4Q23 A;  2Q9Z A;  1WL2 A;  5ILK A;  2Z4X A;  4KVI A;  2OGD A;  2Z4W A;  4KKM A;  4KPD A;  5DJR F;  3WCL A;  4NKF A;  4KVY A;  1YHM A;  1VG2 A;  3N1W F;  2E8T A;  1JFG A;  3N5J F;  2J1P A; 
#chains in the Genus database with same CATH homology
 4JYX A;  1RQJ A;  5DJV F;  3TC1 A;  2ONH A;  3TFN A;  1UBX A;  3ID0 A;  3CC9 A;  1EZF A;  4LA6 A;  1JFA A;  4QPF A;  5IMI A;  4JZB A;  4LIX A;  5E8L A;  1YYR A;  1VG3 A;  4LLT A;  3VJA A;  3QQV A;  1UBV A;  2OPN A;  2OA6 A;  3LDW A;  2E8U A;  4H5C F;  2E91 A;  2QIS A;  4H5D F;  3AQC B;  4EA1 A;  4QXS F;  5IMP A;  4JZX A;  4DWB A;  3CP6 A;  1YHL A;  1V4J A;  5ERO A;  1WL3 A;  3LJI A;  4LPG F;  5E8H A;  1V4H A;  2Z7H A;  3LEE A;  3WEJ A;  5ILJ A;  3LGK A;  3QKC A;  3NRI A;  5IVG A;  1V4I A;  3LG5 A;  3OAC B;  4LFV F;  3M9U A;  3AQ0 A;  3WJN A;  4P0W A;  3M00 A;  3BNY A;  3S4J A;  4PVY F;  4F62 A;  1YV5 A;  3EFQ A;  4LXW A;  5B00 A;  5B03 A;  5B0K A;  3TS7 A;  3Q1O A;  3PDE A;  4DWG A;  5ILI A;  3RMG A;  2PS4 A;  3KRA A;  4L2X F;  3ADZ A;  3CKE A;  5ILY A;  3WJO A;  5HN8 A;  4MC8 A;  2ONG A;  1PS1 A;  3WJK A;  1V4K A;  4LTV A;  1V4E A;  5C05 A;  4LTZ A;  4XQS F;  5AHU B;  3LMD A;  2ZCS A;  4LPH F;  1ZW5 A;  3PYA A;  4OKM A;  2I19 A;  3WC9 A;  5IL8 A;  3P5P A;  2J1O A;  1YYT A;  2E90 A;  3G4F A;  5DIQ F;  4RXE A;  5AYP A;  2VF6 A;  5IKH A;  3RYE A;  2ZCO A;  5DGS F;  3VJ8 A;  3WE9 A;  2Q80 A;  3KRC B;  3V1X A;  3P5R A;  5DHK A;  4P0V A;  5JA0 F;  5IL3 A;  1YYQ A;  1N23 A;  3TFV A;  3M0G A;  5HN7 A;  3WCA A;  3KBK A;  3LOM A;  3V1V A;  5EAT A;  4P0X A;  3Q2Z A;  2Z52 A;  3OAB A;  5B01 A;  5IK9 A;  3LSN A;  3VJ9 A;  3SDQ A;  1UBW A;  2OPM A;  4EA2 A;  3N45 F;  1N20 A;  2O1O A;  2E92 A;  2DH4 A;  1RTR A;  5ERM A;  1WL1 A;  1VG7 A;  4N1Z F;  5JV0 F;  5AEL A;  1KIY A;  1N1Z A;  1YQ7 A;  3VJE A;  4DXJ A;  3KRP B;  4DZW A;  4KQ5 A;  3ASX A;  4LZC A;  3P41 A;  3KB9 A;  3UCA A;  4UMJ A;  3N46 F;  4MC3 A;  4RNQ A;  3W7F A;  2P1C A;  3WCJ A;  3N1V F;  2ZCR A;  2F94 F;  4KK2 A;  3KRF A;  3WSB A;  3VJD A;  1WY0 A;  3N6K F;  2H8O A;  3WCD A;  3ICN A;  4KFA A;  3KRA B;  5H9D A;  3WEH A;  1HXC A;  4RYP A;  1HX9 A;  3N5H F;  3WCE A;  3ICK A;  4F6X A;  4NUA A;  4OMH A;  4EA0 A;  3SAE A;  3SDV A;  3NPK A;  2F8C F;  2E8V A;  4KPJ A;  3SDT A;  1WKZ A;  3M01 A;  2Z50 A;  4GP2 A;  5HNA A;  1YYU A;  4RXA A;  4NFJ F;  4LZ3 A;  4KQU A;  3G4D A;  5B0L A;  5IN8 A;  4KUX A;  4E9U A;  3LVS A;  3LK5 A;  4LA5 A;  2FTZ A;  3APZ A;  3ACW A;  3RBM A;  5JV2 F;  1DI1 A;  5B02 A;  3WCM A;  4HD1 A;  4DI5 A;  4F6V A;  2AEK A;  5A0I A;  3PH7 A;  1HM4 A;  1N24 A;  2PS5 A;  3DYF A;  3ZL6 A;  2AET A;  3ZMB A;  5CG5 A;  1WL0 A;  4K10 A;  2E95 A;  1HM7 A;  5ER8 A;  2PS6 A;  3PYB A;  3ZOU A;  4LFE A;  1HXA A;  5AFX A;  4KWD A;  1UBY A;  3OAC A;  4LUU A;  5B0M A;  4KVD A;  3ZMC A;  3MAV A;  3NF2 A;  3WCB A;  2RAH A;  3Q30 A;  5A0J A;  4NKE A;  3MZV A;  3Q2Q A;  3KRO A;  3IBA A;  4E9Z A;  4PVX F;  5IKA A;  4JXN A;  1YHK A;  3WEG A;  3OYR A;  3WCI A;  1VG4 A;  2F8Z F;  2AZJ A;  4N9U A;  2ZCQ A;  3WSA A;  3WEF A;  2E8W A;  2AEL A;  2Z7I A;  3WCH A;  3NPR A;  5ILZ A;  3M02 A;  4ZQ8 A;  3S9V A;  3SDR A;  5B0I A;  2ZEU A;  3KRC A;  3EZ3 A;  5DHI A;  3AE0 A;  5CG6 A;  2F7M F;  2F92 F;  5IMN A;  4OGU A;  5EAS A;  4XQT F;  4FJQ A;  3LLW A;  5EAU A;  5JV1 F;  3IPI A;  5JUZ F;  2PS7 A;  4RXC A;  4JVJ F;  2ZY1 A;  3N0G A;  1N21 A;  2EWG A;  2E4O A;  3ICM A;  5DGM F;  3VJB A;  3DYG A;  5E8K A;  1N1B A;  3ACY A;  1N22 A;  3DYH A;  4LLS A;  3N49 F;  2Z78 A;  4FP4 A;  4NG6 A;  5I1U A;  4E1E A;  3WEK A;  4NFK F;  4GA3 A;  5IK0 A;  4NFI F;  1DGP A;  1KIZ A;  1HXG A;  3KRP A;  3PKO A;  2E94 A;  2F9K F;  5HN9 A;  5ILH A;  5DJP F;  5ILD A;  3SDU A;  3P8L A;  4KQS A;  4KVW A;  2Z4V A;  5DW7 A;  3OAB B;  3RYW A;  5IM1 A;  3ACX A;  3AQB B;  2Q9Y A;  3TFP A;  3KRO B;  3N3D A;  4JXY A;  4GAX A;  4DHD A;  3N0F A;  3LGZ B;  1RQI A;  3WCF A;  4LOB A;  2F89 F;  4DEM F;  3WCC A;  2Z4Z A;  2AZK A;  2E93 A;  1YYS A;  5KSX F;  1FPS A;  5B0J A;  3WEI A;  3LZ9 A;  4OMG A;  3ICZ A;  3WCG A;  4GP1 A;  5IK6 A;  2Q58 A;  2ZEV A;  2J5C A;  1VG6 A;  3V66 A;  2Z4Y A;  5ERN A;  3ZCD A;  1YJ4 A;  3EGT A;  2FOR A;  4OKZ A;  2PS8 A;  3BNX A;  4RXD A;  4H5E F;  3KRF B;  4XQR F;  4LFG A;  5A0K A;  3VJC A;  4MC0 A;  2E8X A;  2AZL A;  3N3L F;  4LZ0 A;  5DGN F;  1WMW A;  4WK5 A;  5DZ2 A;  3P8R A;  3B7L A;  4Q23 A;  2Q9Z A;  1WL2 A;  5ILK A;  2Z4X A;  4KVI A;  2OGD A;  2Z4W A;  4KKM A;  4KPD A;  5DJR F;  3WCL A;  4NKF A;  4KVY A;  1YHM A;  1VG2 A;  3N1W F;  2E8T A;  1JFG A;  3N5J F;  2J1P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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