3LEEA

Crystal structure of the human squalene synthase complexed with bph-652
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
334
structure length
324
Chain Sequence
SSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Squalene synthetase
publication title Mechanism of Action (and Inhibition) of Head-to-Head Terpene Synthases: A Structural Investigation
rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 119
structure length 324
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3leeA00
3OABA 1N20A 2F92F 3ACXA 3RYEA 3CKEA 4OMGA 3WCMA 5KSXF 2Q9ZA 3EGTA 4DHDA 4LA6A 1N1ZA 1KIYA 3M02A 2FORA 3KRFA 3LK5A 5DJPF 3NF2A 2ZEVA 5JV0F 2DH4A 3RMGA 2Z78A 4NUAA 4XQTF 1VG7A 1YYTA 5IMNA 3Q30A 3ICNA 3QKCA 4RXAA 3QQVA 4JVJF 5B03A 1JFGA 3WEIA 4KPJA 1WMWA 2ZCQA 4N9UA 1HX9A 1V4HA 5B0LA 1YHLA 3SDUA 3WJOA 2PS4A 5HN7A 4KK2A 3KRPB 3TS7A 1V4IA 4NKFA 4EA0A 2E91A 1N22A 5B02A 5IMPA 2VF6A 3WSBA 3ZMCA 2E93A 2E8XA 3N5HF 4F6VA 1RQJA 5IL8A 3P8RA 2AZKA 5A0JA 4L2XF 2OPMA 5H9DA 1YV5A 4OGUA 1ZW5A 4DEMF 1HXGA 2Z7HA 3KRPA 4LTVA 4E9ZA 4LZ3A 3WCCA 3EFQA 2OGDA 4NFJF 3WCEA 3VJEA 1VG4A 2PS8A 5JV1F 3WCAA 3P5PA 2QISA 4LPHF 5IVGA 3SDRA 1WL1A 5E8HA 4H5EF 1VG2A 3OACB 3OYRA 3NPRA 2Z4VA 3LDWA 4EA2A 2I19A 4LOBA 5E8LA 1YYRA 1VG3A 3ICMA 4KQUA 1EZFA 5ERNA 5A0IA 4P0XA 4QPFA 2O1OA 3V1VA 4FJQA 3LLWA 5ER8A 5DJVF 3Q2ZA 5AELA 2Q80A 3N3LF 3OACA 4Q23A 1DGPA 3WC9A 3N5JF 3TFVA 2AZLA 3M9UA 2H8OA 1UBYA 1YHKA 3PKOA 3N49F 2ZCSA 3TC1A 1HM7A 2PS5A 5DGMF 2ZCOA 5IM1A 1WL0A 1N21A 5IK6A 3SAEA 4PVYF 5ILHA 2ONGA 5ILKA 3WCJA 2F8ZF 4K10A 4RNQA 4LZCA 4KVYA 3N1VF 3PDEA 4JXYA 1RQIA 3LSNA 2E8VA 3RYWA 3KB9A 1V4KA 1YJ4A 2F7MF 4LFVF 2Z4ZA 1V4EA 4H5CF 4MC0A 5B0JA 2Z4XA 1UBVA 2E95A 3APZA 3CP6A 4JYXA 3SDTA 4LIXA 3WCDA 3WEHA 3LMDA 3P8LA 3VJ9A 3LJIA 1DI1A 4LLSA 3WSAA 5C05A 4HD1A 4KVDA 4EA1A 4WK5A 1V4JA 5DHIA 5ILYA 1UBXA 5IMIA 3KROB 4KKMA 2Q58A 3KBKA 1RTRA 5IK9A 1JFAA 5IKHA 4LTZA 3ACWA 3KRCB 5HN8A 1WY0A 2PS6A 3N45F 4P0WA 4KFAA 4E1EA 3ASXA 3KROA 3DYFA 2F89F 4OKMA 4MC8A 3AE0A 1YYQA 5I1UA 5B0IA 5DJRF 4QXSF 2Q9YA 3KRCA 3KRAB 3M00A 5CG6A 4LFGA 3IBAA 3WCHA 3MZVA 3N0GA 3PYBA 4JZBA 4NFKF 3VJBA 4OKZA 5ILDA 5EATA 3NRIA 3S9VA 2F9KF 3ZMBA 5IKAA 4JXNA 5IL3A 1WL2A 4UMJA 3KRAA 5B00A 4LXWA 5JV2F 4LLTA 3LG5A 2AELA 4KUXA 2E8WA 2E4OA 3LGKA 3Q1OA 3LGZB 4H5DF 3AQ0A 3N6KF 3N1WF 3N3DA 3CC9A 1VG6A 5IN8A 1YYSA 5DGSF 3WJKA 2P1CA 4DWGA 2AZJA 2Z7IA 4MC3A 2Z52A 3M0GA 5JA0F 4KWDA 3MAVA 3AQCB 3ID0A 2J1PA 4P0VA 1HM4A 3G4DA 5A0KA 3ICZA 4KPDA 5HN9A 3PYAA 2E92A 3V1XA 3ACYA 4OMHA 4F62A 5DHKA 4N1ZF 1WL3A 3LVSA 4RYPA 3WEJA 5DZ2A 1FPSA 5ERMA 2FTZA 3WCLA 3P41A 3LOMA 2EWGA 3V66A 2E94A 3VJAA 3UCAA 3WE9A 2OPNA 1YQ7A 3ZOUA 3ADZA 5CG5A 1N23A 4NG6A 3ZCDA 5EROA 5EAUA 4KVWA 4KQ5A 4KQSA 4RXDA 4LZ0A 3SDVA 4GP2A 2PS7A 5E8KA 3WJNA 3DYHA 5ILJA 2Z50A 1N24A 4LA5A 4PVXF 4LFEA 2OA6A 3WCIA 3NPKA 1N1BA 1HXAA 5AFXA 4DWBA 3WCBA 5ILZA 2F8CF 5AYPA 1KIZA 3TFPA 5DIQF 4RXEA 5HNAA 5ILIA 3AQBB 4XQSF 1HXCA 3LEEA 3M01A 3S4JA 2J1OA 4DXJA 3WEGA 3ZL6A 2AETA 5DW7A 4NKEA 3WEKA 4LPGF 4RXCA 3W7FA 5AHUB 3DYGA 4GAXA 4F6XA 3WEFA 4KVIA 3VJCA 5IK0A 5EASA 5DGNF 3WCFA 2E8UA 5B0MA 1WKZA 4LUUA 3IPIA 4GP1A 3G4FA 1UBWA 3LZ9A 4NFIF 3EZ3A 5JUZF 3RBMA 5B01A 4DI5A 3VJ8A 1YYUA 5B0KA 3PH7A 4FP4A 4E9UA 2F94F 3B7LA 3SDQA 2E90A 2ZCRA 3Q2QA 2RAHA 2AEKA 2ZY1A 4JZXA 4DZWA 2ZEUA 3TFNA 3N46F 2ONHA 1PS1A 3VJDA 3WCGA 1YHMA 3BNXA 3OABB 2E8TA 4GA3A 4XQRF 3N0FA 2Z4WA 3ICKA 2Z4YA 3KRFB 3BNYA 4ZQ8A 3P5RA 2J5CA
chains in the Genus database with same CATH superfamily
3OABA 1N20A 2F92F 3ACXA 3RYEA 3CKEA 4OMGA 3WCMA 5KSXF 2Q9ZA 3EGTA 4DHDA 4LA6A 1N1ZA 1KIYA 3M02A 2FORA 3KRFA 3LK5A 5DJPF 3NF2A 2ZEVA 5JV0F 2DH4A 3RMGA 2Z78A 4NUAA 4XQTF 1VG7A 1YYTA 5IMNA 3Q30A 3ICNA 3QKCA 4RXAA 3QQVA 4JVJF 5B03A 1JFGA 3WEIA 4KPJA 1WMWA 2ZCQA 4N9UA 1HX9A 1V4HA 5B0LA 1YHLA 3SDUA 3WJOA 2PS4A 5HN7A 4KK2A 3KRPB 3TS7A 1V4IA 4NKFA 4EA0A 2E91A 1N22A 5B02A 5IMPA 2VF6A 3WSBA 3ZMCA 2E93A 2E8XA 3N5HF 4F6VA 1RQJA 5IL8A 3P8RA 2AZKA 5A0JA 4L2XF 2OPMA 5H9DA 1YV5A 4OGUA 1ZW5A 4DEMF 1HXGA 2Z7HA 3KRPA 4LTVA 4E9ZA 4LZ3A 3WCCA 3EFQA 2OGDA 4NFJF 3WCEA 3VJEA 1VG4A 2PS8A 5JV1F 3WCAA 3P5PA 2QISA 4LPHF 5IVGA 3SDRA 1WL1A 5E8HA 4H5EF 1VG2A 3OACB 3OYRA 3NPRA 2Z4VA 3LDWA 4EA2A 2I19A 4LOBA 5E8LA 1YYRA 1VG3A 3ICMA 4KQUA 1EZFA 5ERNA 5A0IA 4P0XA 4QPFA 2O1OA 3V1VA 4FJQA 3LLWA 5ER8A 5DJVF 3Q2ZA 5AELA 2Q80A 3N3LF 3OACA 4Q23A 1DGPA 3WC9A 3N5JF 3TFVA 2AZLA 3M9UA 2H8OA 1UBYA 1YHKA 3PKOA 3N49F 2ZCSA 3TC1A 1HM7A 2PS5A 5DGMF 2ZCOA 5IM1A 1WL0A 1N21A 5IK6A 3SAEA 4PVYF 5ILHA 2ONGA 5ILKA 3WCJA 2F8ZF 4K10A 4RNQA 4LZCA 4KVYA 3N1VF 3PDEA 4JXYA 1RQIA 3LSNA 2E8VA 3RYWA 3KB9A 1V4KA 1YJ4A 2F7MF 4LFVF 2Z4ZA 1V4EA 4H5CF 4MC0A 5B0JA 2Z4XA 1UBVA 2E95A 3APZA 3CP6A 4JYXA 3SDTA 4LIXA 3WCDA 3WEHA 3LMDA 3P8LA 3VJ9A 3LJIA 1DI1A 4LLSA 3WSAA 5C05A 4HD1A 4KVDA 4EA1A 4WK5A 1V4JA 5DHIA 5ILYA 1UBXA 5IMIA 3KROB 4KKMA 2Q58A 3KBKA 1RTRA 5IK9A 1JFAA 5IKHA 4LTZA 3ACWA 3KRCB 5HN8A 1WY0A 2PS6A 3N45F 4P0WA 4KFAA 4E1EA 3ASXA 3KROA 3DYFA 2F89F 4OKMA 4MC8A 3AE0A 1YYQA 5I1UA 5B0IA 5DJRF 4QXSF 2Q9YA 3KRCA 3KRAB 3M00A 5CG6A 4LFGA 3IBAA 3WCHA 3MZVA 3N0GA 3PYBA 4JZBA 4NFKF 3VJBA 4OKZA 5ILDA 5EATA 3NRIA 3S9VA 2F9KF 3ZMBA 5IKAA 4JXNA 5IL3A 1WL2A 4UMJA 3KRAA 5B00A 4LXWA 5JV2F 4LLTA 3LG5A 2AELA 4KUXA 2E8WA 2E4OA 3LGKA 3Q1OA 3LGZB 4H5DF 3AQ0A 3N6KF 3N1WF 3N3DA 3CC9A 1VG6A 5IN8A 1YYSA 5DGSF 3WJKA 2P1CA 4DWGA 2AZJA 2Z7IA 4MC3A 2Z52A 3M0GA 5JA0F 4KWDA 3MAVA 3AQCB 3ID0A 2J1PA 4P0VA 1HM4A 3G4DA 5A0KA 3ICZA 4KPDA 5HN9A 3PYAA 2E92A 3V1XA 3ACYA 4OMHA 4F62A 5DHKA 4N1ZF 1WL3A 3LVSA 4RYPA 3WEJA 5DZ2A 1FPSA 5ERMA 2FTZA 3WCLA 3P41A 3LOMA 2EWGA 3V66A 2E94A 3VJAA 3UCAA 3WE9A 2OPNA 1YQ7A 3ZOUA 3ADZA 5CG5A 1N23A 4NG6A 3ZCDA 5EROA 5EAUA 4KVWA 4KQ5A 4KQSA 4RXDA 4LZ0A 3SDVA 4GP2A 2PS7A 5E8KA 3WJNA 3DYHA 5ILJA 2Z50A 1N24A 4LA5A 4PVXF 4LFEA 2OA6A 3WCIA 3NPKA 1N1BA 1HXAA 5AFXA 4DWBA 3WCBA 5ILZA 2F8CF 5AYPA 1KIZA 3TFPA 5DIQF 4RXEA 5HNAA 5ILIA 3AQBB 4XQSF 1HXCA 3LEEA 3M01A 3S4JA 2J1OA 4DXJA 3WEGA 3ZL6A 2AETA 5DW7A 4NKEA 3WEKA 4LPGF 4RXCA 3W7FA 5AHUB 3DYGA 4GAXA 4F6XA 3WEFA 4KVIA 3VJCA 5IK0A 5EASA 5DGNF 3WCFA 2E8UA 5B0MA 1WKZA 4LUUA 3IPIA 4GP1A 3G4FA 1UBWA 3LZ9A 4NFIF 3EZ3A 5JUZF 3RBMA 5B01A 4DI5A 3VJ8A 1YYUA 5B0KA 3PH7A 4FP4A 4E9UA 2F94F 3B7LA 3SDQA 2E90A 2ZCRA 3Q2QA 2RAHA 2AEKA 2ZY1A 4JZXA 4DZWA 2ZEUA 3TFNA 3N46F 2ONHA 1PS1A 3VJDA 3WCGA 1YHMA 3BNXA 3OABB 2E8TA 4GA3A 4XQRF 3N0FA 2Z4WA 3ICKA 2Z4YA 3KRFB 3BNYA 4ZQ8A 3P5RA 2J5CA
chains in the Genus database with same CATH topology
3OABA 1N20A 2F92F 3ACXA 3RYEA 3CKEA 4OMGA 3WCMA 5KSXF 2Q9ZA 3EGTA 4DHDA 4LA6A 1N1ZA 1KIYA 3M02A 2FORA 3KRFA 3LK5A 5DJPF 3NF2A 2ZEVA 5JV0F 2DH4A 3RMGA 2Z78A 4NUAA 4XQTF 1VG7A 1YYTA 5IMNA 3Q30A 3ICNA 3QKCA 4RXAA 3QQVA 4JVJF 5B03A 1JFGA 3WEIA 4KPJA 1WMWA 2ZCQA 4N9UA 1HX9A 1V4HA 5B0LA 1YHLA 3SDUA 3WJOA 2PS4A 5HN7A 4KK2A 3KRPB 3TS7A 1V4IA 4NKFA 4EA0A 2E91A 1N22A 5B02A 5IMPA 2VF6A 3WSBA 3ZMCA 2E93A 2E8XA 3N5HF 4F6VA 1RQJA 5IL8A 3P8RA 2AZKA 5A0JA 4L2XF 2OPMA 5H9DA 1YV5A 4OGUA 1ZW5A 4DEMF 1HXGA 2Z7HA 3KRPA 4LTVA 4E9ZA 4LZ3A 3WCCA 3EFQA 2OGDA 4NFJF 3WCEA 3VJEA 1VG4A 2PS8A 5JV1F 3WCAA 3P5PA 2QISA 4LPHF 5IVGA 3SDRA 1WL1A 5E8HA 4H5EF 1VG2A 3OACB 3OYRA 3NPRA 2Z4VA 3LDWA 4EA2A 2I19A 4LOBA 5E8LA 1YYRA 1VG3A 3ICMA 4KQUA 1EZFA 5ERNA 5A0IA 4P0XA 4QPFA 2O1OA 3V1VA 4FJQA 3LLWA 5ER8A 5DJVF 3Q2ZA 5AELA 2Q80A 3N3LF 3OACA 4Q23A 1DGPA 3WC9A 3N5JF 3TFVA 2AZLA 3M9UA 2H8OA 1UBYA 1YHKA 3PKOA 3N49F 2ZCSA 3TC1A 1HM7A 2PS5A 5DGMF 2ZCOA 5IM1A 1WL0A 1N21A 5IK6A 3SAEA 4PVYF 5ILHA 2ONGA 5ILKA 3WCJA 2F8ZF 4K10A 4RNQA 4LZCA 4KVYA 3N1VF 3PDEA 4JXYA 1RQIA 3LSNA 2E8VA 3RYWA 3KB9A 1V4KA 1YJ4A 2F7MF 4LFVF 2Z4ZA 1V4EA 4H5CF 4MC0A 5B0JA 2Z4XA 1UBVA 2E95A 3APZA 3CP6A 4JYXA 3SDTA 4LIXA 3WCDA 3WEHA 3LMDA 3P8LA 3VJ9A 3LJIA 1DI1A 4LLSA 3WSAA 5C05A 4HD1A 4KVDA 4EA1A 4WK5A 1V4JA 5DHIA 5ILYA 1UBXA 5IMIA 3KROB 4KKMA 2Q58A 3KBKA 1RTRA 5IK9A 1JFAA 5IKHA 4LTZA 3ACWA 3KRCB 5HN8A 1WY0A 2PS6A 3N45F 4P0WA 4KFAA 4E1EA 3ASXA 3KROA 3DYFA 2F89F 4OKMA 4MC8A 3AE0A 1YYQA 5I1UA 5B0IA 5DJRF 4QXSF 2Q9YA 3KRCA 3KRAB 3M00A 5CG6A 4LFGA 3IBAA 3WCHA 3MZVA 3N0GA 3PYBA 4JZBA 4NFKF 3VJBA 4OKZA 5ILDA 5EATA 3NRIA 3S9VA 2F9KF 3ZMBA 5IKAA 4JXNA 5IL3A 1WL2A 4UMJA 3KRAA 5B00A 4LXWA 5JV2F 4LLTA 3LG5A 2AELA 4KUXA 2E8WA 2E4OA 3LGKA 3Q1OA 3LGZB 4H5DF 3AQ0A 3N6KF 3N1WF 3N3DA 3CC9A 1VG6A 5IN8A 1YYSA 5DGSF 3WJKA 2P1CA 4DWGA 2AZJA 2Z7IA 4MC3A 2Z52A 3M0GA 5JA0F 4KWDA 3MAVA 3AQCB 3ID0A 2J1PA 4P0VA 1HM4A 3G4DA 5A0KA 3ICZA 4KPDA 5HN9A 3PYAA 2E92A 3V1XA 3ACYA 4OMHA 4F62A 5DHKA 4N1ZF 1WL3A 3LVSA 4RYPA 3WEJA 5DZ2A 1FPSA 5ERMA 2FTZA 3WCLA 3P41A 3LOMA 2EWGA 3V66A 2E94A 3VJAA 3UCAA 3WE9A 2OPNA 1YQ7A 3ZOUA 3ADZA 5CG5A 1N23A 4NG6A 3ZCDA 5EROA 5EAUA 4KVWA 4KQ5A 4KQSA 4RXDA 4LZ0A 3SDVA 4GP2A 2PS7A 5E8KA 3WJNA 3DYHA 5ILJA 2Z50A 1N24A 4LA5A 4PVXF 4LFEA 2OA6A 3WCIA 3NPKA 1N1BA 1HXAA 5AFXA 4DWBA 3WCBA 5ILZA 2F8CF 5AYPA 1KIZA 3TFPA 5DIQF 4RXEA 5HNAA 5ILIA 3AQBB 4XQSF 1HXCA 3LEEA 3M01A 3S4JA 2J1OA 4DXJA 3WEGA 3ZL6A 2AETA 5DW7A 4NKEA 3WEKA 4LPGF 4RXCA 3W7FA 5AHUB 3DYGA 4GAXA 4F6XA 3WEFA 4KVIA 3VJCA 5IK0A 5EASA 5DGNF 3WCFA 2E8UA 5B0MA 1WKZA 4LUUA 3IPIA 4GP1A 3G4FA 1UBWA 3LZ9A 4NFIF 3EZ3A 5JUZF 3RBMA 5B01A 4DI5A 3VJ8A 1YYUA 5B0KA 3PH7A 4FP4A 4E9UA 2F94F 3B7LA 3SDQA 2E90A 2ZCRA 3Q2QA 2RAHA 2AEKA 2ZY1A 4JZXA 4DZWA 2ZEUA 3TFNA 3N46F 2ONHA 1PS1A 3VJDA 3WCGA 1YHMA 3BNXA 3OABB 2E8TA 4GA3A 4XQRF 3N0FA 2Z4WA 3ICKA 2Z4YA 3KRFB 3BNYA 4ZQ8A 3P5RA 2J5CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OAB A;  1N20 A;  2F92 F;  3ACX A;  3RYE A;  3CKE A;  4OMG A;  3WCM A;  5KSX F;  2Q9Z A;  3EGT A;  4DHD A;  4LA6 A;  1N1Z A;  1KIY A;  3M02 A;  2FOR A;  3KRF A;  3LK5 A;  5DJP F;  3NF2 A;  2ZEV A;  5JV0 F;  2DH4 A;  3RMG A;  2Z78 A;  4NUA A;  4XQT F;  1VG7 A;  1YYT A;  5IMN A;  3Q30 A;  3ICN A;  3QKC A;  4RXA A;  3QQV A;  4JVJ F;  5B03 A;  1JFG A;  3WEI A;  4KPJ A;  1WMW A;  2ZCQ A;  4N9U A;  1HX9 A;  1V4H A;  5B0L A;  1YHL A;  3SDU A;  3WJO A;  2PS4 A;  5HN7 A;  4KK2 A;  3KRP B;  3TS7 A;  1V4I A;  4NKF A;  4EA0 A;  2E91 A;  1N22 A;  5B02 A;  5IMP A;  2VF6 A;  3WSB A;  3ZMC A;  2E93 A;  2E8X A;  3N5H F;  4F6V A;  1RQJ A;  5IL8 A;  3P8R A;  2AZK A;  5A0J A;  4L2X F;  2OPM A;  5H9D A;  1YV5 A;  4OGU A;  1ZW5 A;  4DEM F;  1HXG A;  2Z7H A;  3KRP A;  4LTV A;  4E9Z A;  4LZ3 A;  3WCC A;  3EFQ A;  2OGD A;  4NFJ F;  3WCE A;  3VJE A;  1VG4 A;  2PS8 A;  5JV1 F;  3WCA A;  3P5P A;  2QIS A;  4LPH F;  5IVG A;  3SDR A;  1WL1 A;  5E8H A;  4H5E F;  1VG2 A;  3OAC B;  3OYR A;  3NPR A;  2Z4V A;  3LDW A;  4EA2 A;  2I19 A;  4LOB A;  5E8L A;  1YYR A;  1VG3 A;  3ICM A;  4KQU A;  1EZF A;  5ERN A;  5A0I A;  4P0X A;  4QPF A;  2O1O A;  3V1V A;  4FJQ A;  3LLW A;  5ER8 A;  5DJV F;  3Q2Z A;  5AEL A;  2Q80 A;  3N3L F;  3OAC A;  4Q23 A;  1DGP A;  3WC9 A;  3N5J F;  3TFV A;  2AZL A;  3M9U A;  2H8O A;  1UBY A;  1YHK A;  3PKO A;  3N49 F;  2ZCS A;  3TC1 A;  1HM7 A;  2PS5 A;  5DGM F;  2ZCO A;  5IM1 A;  1WL0 A;  1N21 A;  5IK6 A;  3SAE A;  4PVY F;  5ILH A;  2ONG A;  5ILK A;  3WCJ A;  2F8Z F;  4K10 A;  4RNQ A;  4LZC A;  4KVY A;  3N1V F;  3PDE A;  4JXY A;  1RQI A;  3LSN A;  2E8V A;  3RYW A;  3KB9 A;  1V4K A;  1YJ4 A;  2F7M F;  4LFV F;  2Z4Z A;  1V4E A;  4H5C F;  4MC0 A;  5B0J A;  2Z4X A;  1UBV A;  2E95 A;  3APZ A;  3CP6 A;  4JYX A;  3SDT A;  4LIX A;  3WCD A;  3WEH A;  3LMD A;  3P8L A;  3VJ9 A;  3LJI A;  1DI1 A;  4LLS A;  3WSA A;  5C05 A;  4HD1 A;  4KVD A;  4EA1 A;  4WK5 A;  1V4J A;  5DHI A;  5ILY A;  1UBX A;  5IMI A;  3KRO B;  4KKM A;  2Q58 A;  3KBK A;  1RTR A;  5IK9 A;  1JFA A;  5IKH A;  4LTZ A;  3ACW A;  3KRC B;  5HN8 A;  1WY0 A;  2PS6 A;  3N45 F;  4P0W A;  4KFA A;  4E1E A;  3ASX A;  3KRO A;  3DYF A;  2F89 F;  4OKM A;  4MC8 A;  3AE0 A;  1YYQ A;  5I1U A;  5B0I A;  5DJR F;  4QXS F;  2Q9Y A;  3KRC A;  3KRA B;  3M00 A;  5CG6 A;  4LFG A;  3IBA A;  3WCH A;  3MZV A;  3N0G A;  3PYB A;  4JZB A;  4NFK F;  3VJB A;  4OKZ A;  5ILD A;  5EAT A;  3NRI A;  3S9V A;  2F9K F;  3ZMB A;  5IKA A;  4JXN A;  5IL3 A;  1WL2 A;  4UMJ A;  3KRA A;  5B00 A;  4LXW A;  5JV2 F;  4LLT A;  3LG5 A;  2AEL A;  4KUX A;  2E8W A;  2E4O A;  3LGK A;  3Q1O A;  3LGZ B;  4H5D F;  3AQ0 A;  3N6K F;  3N1W F;  3N3D A;  3CC9 A;  1VG6 A;  5IN8 A;  1YYS A;  5DGS F;  3WJK A;  2P1C A;  4DWG A;  2AZJ A;  2Z7I A;  4MC3 A;  2Z52 A;  3M0G A;  5JA0 F;  4KWD A;  3MAV A;  3AQC B;  3ID0 A;  2J1P A;  4P0V A;  1HM4 A;  3G4D A;  5A0K A;  3ICZ A;  4KPD A;  5HN9 A;  3PYA A;  2E92 A;  3V1X A;  3ACY A;  4OMH A;  4F62 A;  5DHK A;  4N1Z F;  1WL3 A;  3LVS A;  4RYP A;  3WEJ A;  5DZ2 A;  1FPS A;  5ERM A;  2FTZ A;  3WCL A;  3P41 A;  3LOM A;  2EWG A;  3V66 A;  2E94 A;  3VJA A;  3UCA A;  3WE9 A;  2OPN A;  1YQ7 A;  3ZOU A;  3ADZ A;  5CG5 A;  1N23 A;  4NG6 A;  3ZCD A;  5ERO A;  5EAU A;  4KVW A;  4KQ5 A;  4KQS A;  4RXD A;  4LZ0 A;  3SDV A;  4GP2 A;  2PS7 A;  5E8K A;  3WJN A;  3DYH A;  5ILJ A;  2Z50 A;  1N24 A;  4LA5 A;  4PVX F;  4LFE A;  2OA6 A;  3WCI A;  3NPK A;  1N1B A;  1HXA A;  5AFX A;  4DWB A;  3WCB A;  5ILZ A;  2F8C F;  5AYP A;  1KIZ A;  3TFP A;  5DIQ F;  4RXE A;  5HNA A;  5ILI A;  3AQB B;  4XQS F;  1HXC A;  3LEE A;  3M01 A;  3S4J A;  2J1O A;  4DXJ A;  3WEG A;  3ZL6 A;  2AET A;  5DW7 A;  4NKE A;  3WEK A;  4LPG F;  4RXC A;  3W7F A;  5AHU B;  3DYG A;  4GAX A;  4F6X A;  3WEF A;  4KVI A;  3VJC A;  5IK0 A;  5EAS A;  5DGN F;  3WCF A;  2E8U A;  5B0M A;  1WKZ A;  4LUU A;  3IPI A;  4GP1 A;  3G4F A;  1UBW A;  3LZ9 A;  4NFI F;  3EZ3 A;  5JUZ F;  3RBM A;  5B01 A;  4DI5 A;  3VJ8 A;  1YYU A;  5B0K A;  3PH7 A;  4FP4 A;  4E9U A;  2F94 F;  3B7L A;  3SDQ A;  2E90 A;  2ZCR A;  3Q2Q A;  2RAH A;  2AEK A;  2ZY1 A;  4JZX A;  4DZW A;  2ZEU A;  3TFN A;  3N46 F;  2ONH A;  1PS1 A;  3VJD A;  3WCG A;  1YHM A;  3BNX A;  3OAB B;  2E8T A;  4GA3 A;  4XQR F;  3N0F A;  2Z4W A;  3ICK A;  2Z4Y A;  3KRF B;  3BNY A;  4ZQ8 A;  3P5R A;  2J5C A; 
#chains in the Genus database with same CATH topology
 3OAB A;  1N20 A;  2F92 F;  3ACX A;  3RYE A;  3CKE A;  4OMG A;  3WCM A;  5KSX F;  2Q9Z A;  3EGT A;  4DHD A;  4LA6 A;  1N1Z A;  1KIY A;  3M02 A;  2FOR A;  3KRF A;  3LK5 A;  5DJP F;  3NF2 A;  2ZEV A;  5JV0 F;  2DH4 A;  3RMG A;  2Z78 A;  4NUA A;  4XQT F;  1VG7 A;  1YYT A;  5IMN A;  3Q30 A;  3ICN A;  3QKC A;  4RXA A;  3QQV A;  4JVJ F;  5B03 A;  1JFG A;  3WEI A;  4KPJ A;  1WMW A;  2ZCQ A;  4N9U A;  1HX9 A;  1V4H A;  5B0L A;  1YHL A;  3SDU A;  3WJO A;  2PS4 A;  5HN7 A;  4KK2 A;  3KRP B;  3TS7 A;  1V4I A;  4NKF A;  4EA0 A;  2E91 A;  1N22 A;  5B02 A;  5IMP A;  2VF6 A;  3WSB A;  3ZMC A;  2E93 A;  2E8X A;  3N5H F;  4F6V A;  1RQJ A;  5IL8 A;  3P8R A;  2AZK A;  5A0J A;  4L2X F;  2OPM A;  5H9D A;  1YV5 A;  4OGU A;  1ZW5 A;  4DEM F;  1HXG A;  2Z7H A;  3KRP A;  4LTV A;  4E9Z A;  4LZ3 A;  3WCC A;  3EFQ A;  2OGD A;  4NFJ F;  3WCE A;  3VJE A;  1VG4 A;  2PS8 A;  5JV1 F;  3WCA A;  3P5P A;  2QIS A;  4LPH F;  5IVG A;  3SDR A;  1WL1 A;  5E8H A;  4H5E F;  1VG2 A;  3OAC B;  3OYR A;  3NPR A;  2Z4V A;  3LDW A;  4EA2 A;  2I19 A;  4LOB A;  5E8L A;  1YYR A;  1VG3 A;  3ICM A;  4KQU A;  1EZF A;  5ERN A;  5A0I A;  4P0X A;  4QPF A;  2O1O A;  3V1V A;  4FJQ A;  3LLW A;  5ER8 A;  5DJV F;  3Q2Z A;  5AEL A;  2Q80 A;  3N3L F;  3OAC A;  4Q23 A;  1DGP A;  3WC9 A;  3N5J F;  3TFV A;  2AZL A;  3M9U A;  2H8O A;  1UBY A;  1YHK A;  3PKO A;  3N49 F;  2ZCS A;  3TC1 A;  1HM7 A;  2PS5 A;  5DGM F;  2ZCO A;  5IM1 A;  1WL0 A;  1N21 A;  5IK6 A;  3SAE A;  4PVY F;  5ILH A;  2ONG A;  5ILK A;  3WCJ A;  2F8Z F;  4K10 A;  4RNQ A;  4LZC A;  4KVY A;  3N1V F;  3PDE A;  4JXY A;  1RQI A;  3LSN A;  2E8V A;  3RYW A;  3KB9 A;  1V4K A;  1YJ4 A;  2F7M F;  4LFV F;  2Z4Z A;  1V4E A;  4H5C F;  4MC0 A;  5B0J A;  2Z4X A;  1UBV A;  2E95 A;  3APZ A;  3CP6 A;  4JYX A;  3SDT A;  4LIX A;  3WCD A;  3WEH A;  3LMD A;  3P8L A;  3VJ9 A;  3LJI A;  1DI1 A;  4LLS A;  3WSA A;  5C05 A;  4HD1 A;  4KVD A;  4EA1 A;  4WK5 A;  1V4J A;  5DHI A;  5ILY A;  1UBX A;  5IMI A;  3KRO B;  4KKM A;  2Q58 A;  3KBK A;  1RTR A;  5IK9 A;  1JFA A;  5IKH A;  4LTZ A;  3ACW A;  3KRC B;  5HN8 A;  1WY0 A;  2PS6 A;  3N45 F;  4P0W A;  4KFA A;  4E1E A;  3ASX A;  3KRO A;  3DYF A;  2F89 F;  4OKM A;  4MC8 A;  3AE0 A;  1YYQ A;  5I1U A;  5B0I A;  5DJR F;  4QXS F;  2Q9Y A;  3KRC A;  3KRA B;  3M00 A;  5CG6 A;  4LFG A;  3IBA A;  3WCH A;  3MZV A;  3N0G A;  3PYB A;  4JZB A;  4NFK F;  3VJB A;  4OKZ A;  5ILD A;  5EAT A;  3NRI A;  3S9V A;  2F9K F;  3ZMB A;  5IKA A;  4JXN A;  5IL3 A;  1WL2 A;  4UMJ A;  3KRA A;  5B00 A;  4LXW A;  5JV2 F;  4LLT A;  3LG5 A;  2AEL A;  4KUX A;  2E8W A;  2E4O A;  3LGK A;  3Q1O A;  3LGZ B;  4H5D F;  3AQ0 A;  3N6K F;  3N1W F;  3N3D A;  3CC9 A;  1VG6 A;  5IN8 A;  1YYS A;  5DGS F;  3WJK A;  2P1C A;  4DWG A;  2AZJ A;  2Z7I A;  4MC3 A;  2Z52 A;  3M0G A;  5JA0 F;  4KWD A;  3MAV A;  3AQC B;  3ID0 A;  2J1P A;  4P0V A;  1HM4 A;  3G4D A;  5A0K A;  3ICZ A;  4KPD A;  5HN9 A;  3PYA A;  2E92 A;  3V1X A;  3ACY A;  4OMH A;  4F62 A;  5DHK A;  4N1Z F;  1WL3 A;  3LVS A;  4RYP A;  3WEJ A;  5DZ2 A;  1FPS A;  5ERM A;  2FTZ A;  3WCL A;  3P41 A;  3LOM A;  2EWG A;  3V66 A;  2E94 A;  3VJA A;  3UCA A;  3WE9 A;  2OPN A;  1YQ7 A;  3ZOU A;  3ADZ A;  5CG5 A;  1N23 A;  4NG6 A;  3ZCD A;  5ERO A;  5EAU A;  4KVW A;  4KQ5 A;  4KQS A;  4RXD A;  4LZ0 A;  3SDV A;  4GP2 A;  2PS7 A;  5E8K A;  3WJN A;  3DYH A;  5ILJ A;  2Z50 A;  1N24 A;  4LA5 A;  4PVX F;  4LFE A;  2OA6 A;  3WCI A;  3NPK A;  1N1B A;  1HXA A;  5AFX A;  4DWB A;  3WCB A;  5ILZ A;  2F8C F;  5AYP A;  1KIZ A;  3TFP A;  5DIQ F;  4RXE A;  5HNA A;  5ILI A;  3AQB B;  4XQS F;  1HXC A;  3LEE A;  3M01 A;  3S4J A;  2J1O A;  4DXJ A;  3WEG A;  3ZL6 A;  2AET A;  5DW7 A;  4NKE A;  3WEK A;  4LPG F;  4RXC A;  3W7F A;  5AHU B;  3DYG A;  4GAX A;  4F6X A;  3WEF A;  4KVI A;  3VJC A;  5IK0 A;  5EAS A;  5DGN F;  3WCF A;  2E8U A;  5B0M A;  1WKZ A;  4LUU A;  3IPI A;  4GP1 A;  3G4F A;  1UBW A;  3LZ9 A;  4NFI F;  3EZ3 A;  5JUZ F;  3RBM A;  5B01 A;  4DI5 A;  3VJ8 A;  1YYU A;  5B0K A;  3PH7 A;  4FP4 A;  4E9U A;  2F94 F;  3B7L A;  3SDQ A;  2E90 A;  2ZCR A;  3Q2Q A;  2RAH A;  2AEK A;  2ZY1 A;  4JZX A;  4DZW A;  2ZEU A;  3TFN A;  3N46 F;  2ONH A;  1PS1 A;  3VJD A;  3WCG A;  1YHM A;  3BNX A;  3OAB B;  2E8T A;  4GA3 A;  4XQR F;  3N0F A;  2Z4W A;  3ICK A;  2Z4Y A;  3KRF B;  3BNY A;  4ZQ8 A;  3P5R A;  2J5C A; 
#chains in the Genus database with same CATH homology
 3OAB A;  1N20 A;  2F92 F;  3ACX A;  3RYE A;  3CKE A;  4OMG A;  3WCM A;  5KSX F;  2Q9Z A;  3EGT A;  4DHD A;  4LA6 A;  1N1Z A;  1KIY A;  3M02 A;  2FOR A;  3KRF A;  3LK5 A;  5DJP F;  3NF2 A;  2ZEV A;  5JV0 F;  2DH4 A;  3RMG A;  2Z78 A;  4NUA A;  4XQT F;  1VG7 A;  1YYT A;  5IMN A;  3Q30 A;  3ICN A;  3QKC A;  4RXA A;  3QQV A;  4JVJ F;  5B03 A;  1JFG A;  3WEI A;  4KPJ A;  1WMW A;  2ZCQ A;  4N9U A;  1HX9 A;  1V4H A;  5B0L A;  1YHL A;  3SDU A;  3WJO A;  2PS4 A;  5HN7 A;  4KK2 A;  3KRP B;  3TS7 A;  1V4I A;  4NKF A;  4EA0 A;  2E91 A;  1N22 A;  5B02 A;  5IMP A;  2VF6 A;  3WSB A;  3ZMC A;  2E93 A;  2E8X A;  3N5H F;  4F6V A;  1RQJ A;  5IL8 A;  3P8R A;  2AZK A;  5A0J A;  4L2X F;  2OPM A;  5H9D A;  1YV5 A;  4OGU A;  1ZW5 A;  4DEM F;  1HXG A;  2Z7H A;  3KRP A;  4LTV A;  4E9Z A;  4LZ3 A;  3WCC A;  3EFQ A;  2OGD A;  4NFJ F;  3WCE A;  3VJE A;  1VG4 A;  2PS8 A;  5JV1 F;  3WCA A;  3P5P A;  2QIS A;  4LPH F;  5IVG A;  3SDR A;  1WL1 A;  5E8H A;  4H5E F;  1VG2 A;  3OAC B;  3OYR A;  3NPR A;  2Z4V A;  3LDW A;  4EA2 A;  2I19 A;  4LOB A;  5E8L A;  1YYR A;  1VG3 A;  3ICM A;  4KQU A;  1EZF A;  5ERN A;  5A0I A;  4P0X A;  4QPF A;  2O1O A;  3V1V A;  4FJQ A;  3LLW A;  5ER8 A;  5DJV F;  3Q2Z A;  5AEL A;  2Q80 A;  3N3L F;  3OAC A;  4Q23 A;  1DGP A;  3WC9 A;  3N5J F;  3TFV A;  2AZL A;  3M9U A;  2H8O A;  1UBY A;  1YHK A;  3PKO A;  3N49 F;  2ZCS A;  3TC1 A;  1HM7 A;  2PS5 A;  5DGM F;  2ZCO A;  5IM1 A;  1WL0 A;  1N21 A;  5IK6 A;  3SAE A;  4PVY F;  5ILH A;  2ONG A;  5ILK A;  3WCJ A;  2F8Z F;  4K10 A;  4RNQ A;  4LZC A;  4KVY A;  3N1V F;  3PDE A;  4JXY A;  1RQI A;  3LSN A;  2E8V A;  3RYW A;  3KB9 A;  1V4K A;  1YJ4 A;  2F7M F;  4LFV F;  2Z4Z A;  1V4E A;  4H5C F;  4MC0 A;  5B0J A;  2Z4X A;  1UBV A;  2E95 A;  3APZ A;  3CP6 A;  4JYX A;  3SDT A;  4LIX A;  3WCD A;  3WEH A;  3LMD A;  3P8L A;  3VJ9 A;  3LJI A;  1DI1 A;  4LLS A;  3WSA A;  5C05 A;  4HD1 A;  4KVD A;  4EA1 A;  4WK5 A;  1V4J A;  5DHI A;  5ILY A;  1UBX A;  5IMI A;  3KRO B;  4KKM A;  2Q58 A;  3KBK A;  1RTR A;  5IK9 A;  1JFA A;  5IKH A;  4LTZ A;  3ACW A;  3KRC B;  5HN8 A;  1WY0 A;  2PS6 A;  3N45 F;  4P0W A;  4KFA A;  4E1E A;  3ASX A;  3KRO A;  3DYF A;  2F89 F;  4OKM A;  4MC8 A;  3AE0 A;  1YYQ A;  5I1U A;  5B0I A;  5DJR F;  4QXS F;  2Q9Y A;  3KRC A;  3KRA B;  3M00 A;  5CG6 A;  4LFG A;  3IBA A;  3WCH A;  3MZV A;  3N0G A;  3PYB A;  4JZB A;  4NFK F;  3VJB A;  4OKZ A;  5ILD A;  5EAT A;  3NRI A;  3S9V A;  2F9K F;  3ZMB A;  5IKA A;  4JXN A;  5IL3 A;  1WL2 A;  4UMJ A;  3KRA A;  5B00 A;  4LXW A;  5JV2 F;  4LLT A;  3LG5 A;  2AEL A;  4KUX A;  2E8W A;  2E4O A;  3LGK A;  3Q1O A;  3LGZ B;  4H5D F;  3AQ0 A;  3N6K F;  3N1W F;  3N3D A;  3CC9 A;  1VG6 A;  5IN8 A;  1YYS A;  5DGS F;  3WJK A;  2P1C A;  4DWG A;  2AZJ A;  2Z7I A;  4MC3 A;  2Z52 A;  3M0G A;  5JA0 F;  4KWD A;  3MAV A;  3AQC B;  3ID0 A;  2J1P A;  4P0V A;  1HM4 A;  3G4D A;  5A0K A;  3ICZ A;  4KPD A;  5HN9 A;  3PYA A;  2E92 A;  3V1X A;  3ACY A;  4OMH A;  4F62 A;  5DHK A;  4N1Z F;  1WL3 A;  3LVS A;  4RYP A;  3WEJ A;  5DZ2 A;  1FPS A;  5ERM A;  2FTZ A;  3WCL A;  3P41 A;  3LOM A;  2EWG A;  3V66 A;  2E94 A;  3VJA A;  3UCA A;  3WE9 A;  2OPN A;  1YQ7 A;  3ZOU A;  3ADZ A;  5CG5 A;  1N23 A;  4NG6 A;  3ZCD A;  5ERO A;  5EAU A;  4KVW A;  4KQ5 A;  4KQS A;  4RXD A;  4LZ0 A;  3SDV A;  4GP2 A;  2PS7 A;  5E8K A;  3WJN A;  3DYH A;  5ILJ A;  2Z50 A;  1N24 A;  4LA5 A;  4PVX F;  4LFE A;  2OA6 A;  3WCI A;  3NPK A;  1N1B A;  1HXA A;  5AFX A;  4DWB A;  3WCB A;  5ILZ A;  2F8C F;  5AYP A;  1KIZ A;  3TFP A;  5DIQ F;  4RXE A;  5HNA A;  5ILI A;  3AQB B;  4XQS F;  1HXC A;  3LEE A;  3M01 A;  3S4J A;  2J1O A;  4DXJ A;  3WEG A;  3ZL6 A;  2AET A;  5DW7 A;  4NKE A;  3WEK A;  4LPG F;  4RXC A;  3W7F A;  5AHU B;  3DYG A;  4GAX A;  4F6X A;  3WEF A;  4KVI A;  3VJC A;  5IK0 A;  5EAS A;  5DGN F;  3WCF A;  2E8U A;  5B0M A;  1WKZ A;  4LUU A;  3IPI A;  4GP1 A;  3G4F A;  1UBW A;  3LZ9 A;  4NFI F;  3EZ3 A;  5JUZ F;  3RBM A;  5B01 A;  4DI5 A;  3VJ8 A;  1YYU A;  5B0K A;  3PH7 A;  4FP4 A;  4E9U A;  2F94 F;  3B7L A;  3SDQ A;  2E90 A;  2ZCR A;  3Q2Q A;  2RAH A;  2AEK A;  2ZY1 A;  4JZX A;  4DZW A;  2ZEU A;  3TFN A;  3N46 F;  2ONH A;  1PS1 A;  3VJD A;  3WCG A;  1YHM A;  3BNX A;  3OAB B;  2E8T A;  4GA3 A;  4XQR F;  3N0F A;  2Z4W A;  3ICK A;  2Z4Y A;  3KRF B;  3BNY A;  4ZQ8 A;  3P5R A;  2J5C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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