3LEEA

Crystal structure of the human squalene synthase complexed with bph-652
Total Genus 119
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
119
sequence length
334
structure length
324
Chain Sequence
SSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Squalene synthetase
publication title Mechanism of Action (and Inhibition) of Head-to-Head Terpene Synthases: A Structural Investigation
rcsb
source organism Homo sapiens
total genus 119
structure length 324
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3leeA00
4RXDA 5JA0F 3SDQA 4LZCA 3ACXA 5IN8A 3KBKA 3VJAA 5IM1A 3ADZA 1YJ4A 4JZXA 1UBWA 2ZCRA 1YYQA 3AE0A 2PS5A 3MZVA 3WCMA 3P5PA 2Z7HA 4EA1A 4UMJA 3WJKA 2QISA 3WEGA 3LG5A 4LTVA 4L2XF 3N3LF 1YHMA 5B0JA 5DGMF 3EGTA 2ZY1A 3WCBA 4KUXA 1YYRA 2Q80A 4DWGA 4MC3A 4DZWA 1VG4A 4P0VA 4KQSA 4MC8A 2VF6A 5AFXA 5DHIA 1YYTA 3SDRA 5DGSF 4GP2A 2ONGA 4KFAA 3LDWA 4KPDA 3ICZA 3RMGA 4P0WA 2OPMA 3DYGA 1HM4A 3M00A 4LOBA 3SDVA 4KK2A 5DZ2A 4K10A 4JVJF 4N9UA 2PS4A 3WCAA 3WEHA 3SDTA 5ILYA 2E95A 3TFPA 2H8OA 4KVYA 2E93A 4JYXA 1HX9A 3DYFA 1N21A 3WCLA 3N5HF 3OABB 3VJEA 3WEKA 2ZEVA 1UBXA 3G4DA 1HXCA 5B0IA 2Z50A 2ZCOA 3KRCB 5IK0A 1VG6A 1VG2A 3WCFA 5HN8A 5ILZA 3WCGA 5B0KA 3OABA 3B7LA 2O1OA 3ZMBA 5IK6A 3VJ8A 3NF2A 5JV2F 3KRCA 3PKOA 2F9KF 4OMGA 4NFKF 3N46F 4LPGF 2E8WA 3WCJA 2E8VA 1N24A 3ID0A 4RNQA 5B0MA 3ICKA 5CG5A 1N22A 2AELA 5DW7A 5B02A 1HXGA 2ZEUA 4LZ0A 3PYBA 5JV1F 5CG6A 5EAUA 3M01A 5I1UA 5JUZF 4GAXA 5E8LA 3PDEA 2Z4VA 4NG6A 5IL8A 5DJVF 3CP6A 3DYHA 3N5JF 3WCHA 5KSXF 3AQBB 4HD1A 4JZBA 5EASA 3TFNA 4H5DF 1WMWA 2OPNA 4F6XA 4KWDA 2Q9ZA 1WY0A 4LA6A 2F7MF 5ERMA 5C05A 1FPSA 1V4KA 4DI5A 4F6VA 4NFJF 3OYRA 4E1EA 3ICNA 3Q2ZA 1UBYA 4KVDA 5IMPA 3WJOA 3M9UA 4QXSF 5DGNF 2J1PA 3BNXA 3N1VF 4E9ZA 1WL0A 4MC0A 3WSAA 2F8CF 5DIQF 2J1OA 3WE9A 4KVIA 3RYWA 3TFVA 2Z4XA 4OMHA 4RXAA 1V4HA 2AZLA 1V4IA 3VJCA 1YYSA 3ASXA 5HN7A 4NKFA 5AHUB 5HN9A 3WCIA 5B03A 1ZW5A 4NUAA 3LLWA 3LJIA 3VJBA 3LEEA 5B00A 5B01A 3NPRA 2I19A 2E8UA 3IBAA 1JFAA 1UBVA 3V1XA 4OGUA 4RYPA 3M02A 3P5RA 2E90A 4DWBA 3KB9A 4KKMA 4E9UA 3ACWA 5E8HA 5AELA 5IVGA 3LGZB 1YHLA 1PS1A 5ILIA 2PS6A 5IKAA 3WCDA 3NPKA 3P8LA 3N45F 4DXJA 3QKCA 3KROB 2PS7A 3SAEA 3Q2QA 4LUUA 3IPIA 2Z4YA 2Z78A 5AYPA 3CKEA 2AEKA 3NRIA 1RQJA 3UCAA 4FJQA 1YV5A 5ILJA 2E4OA 2EWGA 4ZQ8A 4LTZA 3KROA 2E8XA 3KRAB 2P1CA 3WCEA 3APZA 2E92A 3OACB 3WEFA 3N0GA 4KPJA 4LLSA 5A0IA 1HM7A 3WCCA 3ZCDA 4KQUA 2AZJA 1N1ZA 4LPHF 4GA3A 2AETA 1WL2A 3KRPB 2FORA 3WJNA 3QQVA 3MAVA 4WK5A 3ACYA 4OKZA 3KRAA 3LZ9A 3OACA 3N6KF 4QPFA 5ILHA 3WC9A 2Z4ZA 2PS8A 3V66A 1WL1A 3KRPA 3S4JA 4JXYA 4LIXA 3N3DA 3M0GA 4KQ5A 4H5EF 4XQRF 3ZL6A 4XQSF 4PVYF 5IKHA 2ONHA 4JXNA 5ERNA 2F92F 5A0JA 5EATA 4KVWA 1V4EA 2Z4WA 2ZCQA 5DJPF 4PVXF 3ZOUA 3Q1OA 4XQTF 1V4JA 5JV0F 3S9VA 4Q23A 1EZFA 4RXEA 2E91A 1KIZA 3SDUA 2OA6A 3N1WF 3WEIA 3PH7A 1RTRA 1VG3A 4LXWA 5E8KA 4F62A 5IK9A 2E94A 2RAHA 4H5CF 4P0XA 1KIYA 4NKEA 4NFIF 3AQCB 5HNAA 5DHKA 3LSNA 2OGDA 2FTZA 4RXCA 3VJ9A 5ILKA 3N0FA 3P41A 3RBMA 5ILDA 3VJDA 1WKZA 3W7FA 4GP1A 3CC9A 3LVSA 4LFVF 1N23A 1RQIA 4OKMA 3LOMA 3ICMA 3EZ3A 3TS7A 1YQ7A 2Q9YA 4DHDA 3BNYA 2E8TA 2F8ZF 1N1BA 1JFGA 3WSBA 1DI1A 3KRFB 4LZ3A 5EROA 5ER8A 2J5CA 5IMNA 3EFQA 3WEJA 3P8RA 3Q30A 2DH4A 3PYAA 1WL3A 1DGPA 1N20A 4LFEA 5DJRF 3RYEA 1YYUA 3G4FA 5IL3A 2Z52A 3ZMCA 2F94F 4N1ZF 2AZKA 1YHKA 5IMIA 3KRFA 3V1VA 3N49F 1HXAA 5A0KA 1VG7A 3AQ0A 4EA0A 4LFGA 2Z7IA 4DEMF 2Q58A 4EA2A 3TC1A 2F89F 4LA5A 3LGKA 3LK5A 2ZCSA 4LLTA 5H9DA 4FP4A 5B0LA 3LMDA
chains in the Genus database with same CATH superfamily
4RXDA 5JA0F 3SDQA 4LZCA 3ACXA 5IN8A 3KBKA 3VJAA 5IM1A 3ADZA 1YJ4A 4JZXA 1UBWA 2ZCRA 1YYQA 3AE0A 2PS5A 3MZVA 3WCMA 3P5PA 2Z7HA 4EA1A 4UMJA 3WJKA 2QISA 3WEGA 3LG5A 4LTVA 4L2XF 3N3LF 1YHMA 5B0JA 5DGMF 3EGTA 2ZY1A 3WCBA 4KUXA 1YYRA 2Q80A 4DWGA 4MC3A 4DZWA 1VG4A 4P0VA 4KQSA 4MC8A 2VF6A 5AFXA 5DHIA 1YYTA 3SDRA 5DGSF 4GP2A 2ONGA 4KFAA 3LDWA 4KPDA 3ICZA 3RMGA 4P0WA 2OPMA 3DYGA 1HM4A 3M00A 4LOBA 3SDVA 4KK2A 5DZ2A 4K10A 4JVJF 4N9UA 2PS4A 3WCAA 3WEHA 3SDTA 5ILYA 2E95A 3TFPA 2H8OA 4KVYA 2E93A 4JYXA 1HX9A 3DYFA 1N21A 3WCLA 3N5HF 3OABB 3VJEA 3WEKA 2ZEVA 1UBXA 3G4DA 1HXCA 5B0IA 2Z50A 2ZCOA 3KRCB 5IK0A 1VG6A 1VG2A 3WCFA 5HN8A 5ILZA 3WCGA 5B0KA 3OABA 3B7LA 2O1OA 3ZMBA 5IK6A 3VJ8A 3NF2A 5JV2F 3KRCA 3PKOA 2F9KF 4OMGA 4NFKF 3N46F 4LPGF 2E8WA 3WCJA 2E8VA 1N24A 3ID0A 4RNQA 5B0MA 3ICKA 5CG5A 1N22A 2AELA 5DW7A 5B02A 1HXGA 2ZEUA 4LZ0A 3PYBA 5JV1F 5CG6A 5EAUA 3M01A 5I1UA 5JUZF 4GAXA 5E8LA 3PDEA 2Z4VA 4NG6A 5IL8A 5DJVF 3CP6A 3DYHA 3N5JF 3WCHA 5KSXF 3AQBB 4HD1A 4JZBA 5EASA 3TFNA 4H5DF 1WMWA 2OPNA 4F6XA 4KWDA 2Q9ZA 1WY0A 4LA6A 2F7MF 5ERMA 5C05A 1FPSA 1V4KA 4DI5A 4F6VA 4NFJF 3OYRA 4E1EA 3ICNA 3Q2ZA 1UBYA 4KVDA 5IMPA 3WJOA 3M9UA 4QXSF 5DGNF 2J1PA 3BNXA 3N1VF 4E9ZA 1WL0A 4MC0A 3WSAA 2F8CF 5DIQF 2J1OA 3WE9A 4KVIA 3RYWA 3TFVA 2Z4XA 4OMHA 4RXAA 1V4HA 2AZLA 1V4IA 3VJCA 1YYSA 3ASXA 5HN7A 4NKFA 5AHUB 5HN9A 3WCIA 5B03A 1ZW5A 4NUAA 3LLWA 3LJIA 3VJBA 3LEEA 5B00A 5B01A 3NPRA 2I19A 2E8UA 3IBAA 1JFAA 1UBVA 3V1XA 4OGUA 4RYPA 3M02A 3P5RA 2E90A 4DWBA 3KB9A 4KKMA 4E9UA 3ACWA 5E8HA 5AELA 5IVGA 3LGZB 1YHLA 1PS1A 5ILIA 2PS6A 5IKAA 3WCDA 3NPKA 3P8LA 3N45F 4DXJA 3QKCA 3KROB 2PS7A 3SAEA 3Q2QA 4LUUA 3IPIA 2Z4YA 2Z78A 5AYPA 3CKEA 2AEKA 3NRIA 1RQJA 3UCAA 4FJQA 1YV5A 5ILJA 2E4OA 2EWGA 4ZQ8A 4LTZA 3KROA 2E8XA 3KRAB 2P1CA 3WCEA 3APZA 2E92A 3OACB 3WEFA 3N0GA 4KPJA 4LLSA 5A0IA 1HM7A 3WCCA 3ZCDA 4KQUA 2AZJA 1N1ZA 4LPHF 4GA3A 2AETA 1WL2A 3KRPB 2FORA 3WJNA 3QQVA 3MAVA 4WK5A 3ACYA 4OKZA 3KRAA 3LZ9A 3OACA 3N6KF 4QPFA 5ILHA 3WC9A 2Z4ZA 2PS8A 3V66A 1WL1A 3KRPA 3S4JA 4JXYA 4LIXA 3N3DA 3M0GA 4KQ5A 4H5EF 4XQRF 3ZL6A 4XQSF 4PVYF 5IKHA 2ONHA 4JXNA 5ERNA 2F92F 5A0JA 5EATA 4KVWA 1V4EA 2Z4WA 2ZCQA 5DJPF 4PVXF 3ZOUA 3Q1OA 4XQTF 1V4JA 5JV0F 3S9VA 4Q23A 1EZFA 4RXEA 2E91A 1KIZA 3SDUA 2OA6A 3N1WF 3WEIA 3PH7A 1RTRA 1VG3A 4LXWA 5E8KA 4F62A 5IK9A 2E94A 2RAHA 4H5CF 4P0XA 1KIYA 4NKEA 4NFIF 3AQCB 5HNAA 5DHKA 3LSNA 2OGDA 2FTZA 4RXCA 3VJ9A 5ILKA 3N0FA 3P41A 3RBMA 5ILDA 3VJDA 1WKZA 3W7FA 4GP1A 3CC9A 3LVSA 4LFVF 1N23A 1RQIA 4OKMA 3LOMA 3ICMA 3EZ3A 3TS7A 1YQ7A 2Q9YA 4DHDA 3BNYA 2E8TA 2F8ZF 1N1BA 1JFGA 3WSBA 1DI1A 3KRFB 4LZ3A 5EROA 5ER8A 2J5CA 5IMNA 3EFQA 3WEJA 3P8RA 3Q30A 2DH4A 3PYAA 1WL3A 1DGPA 1N20A 4LFEA 5DJRF 3RYEA 1YYUA 3G4FA 5IL3A 2Z52A 3ZMCA 2F94F 4N1ZF 2AZKA 1YHKA 5IMIA 3KRFA 3V1VA 3N49F 1HXAA 5A0KA 1VG7A 3AQ0A 4EA0A 4LFGA 2Z7IA 4DEMF 2Q58A 4EA2A 3TC1A 2F89F 4LA5A 3LGKA 3LK5A 2ZCSA 4LLTA 5H9DA 4FP4A 5B0LA 3LMDA
chains in the Genus database with same CATH topology
4RXDA 5JA0F 3SDQA 4LZCA 3ACXA 5IN8A 3KBKA 3VJAA 5IM1A 3ADZA 1YJ4A 4JZXA 1UBWA 2ZCRA 1YYQA 3AE0A 2PS5A 3MZVA 3WCMA 3P5PA 2Z7HA 4EA1A 4UMJA 3WJKA 2QISA 3WEGA 3LG5A 4LTVA 4L2XF 3N3LF 1YHMA 5B0JA 5DGMF 3EGTA 2ZY1A 3WCBA 4KUXA 1YYRA 2Q80A 4DWGA 4MC3A 4DZWA 1VG4A 4P0VA 4KQSA 4MC8A 2VF6A 5AFXA 5DHIA 1YYTA 3SDRA 5DGSF 4GP2A 2ONGA 4KFAA 3LDWA 4KPDA 3ICZA 3RMGA 4P0WA 2OPMA 3DYGA 1HM4A 3M00A 4LOBA 3SDVA 4KK2A 5DZ2A 4K10A 4JVJF 4N9UA 2PS4A 3WCAA 3WEHA 3SDTA 5ILYA 2E95A 3TFPA 2H8OA 4KVYA 2E93A 4JYXA 1HX9A 3DYFA 1N21A 3WCLA 3N5HF 3OABB 3VJEA 3WEKA 2ZEVA 1UBXA 3G4DA 1HXCA 5B0IA 2Z50A 2ZCOA 3KRCB 5IK0A 1VG6A 1VG2A 3WCFA 5HN8A 5ILZA 3WCGA 5B0KA 3OABA 3B7LA 2O1OA 3ZMBA 5IK6A 3VJ8A 3NF2A 5JV2F 3KRCA 3PKOA 2F9KF 4OMGA 4NFKF 3N46F 4LPGF 2E8WA 3WCJA 2E8VA 1N24A 3ID0A 4RNQA 5B0MA 3ICKA 5CG5A 1N22A 2AELA 5DW7A 5B02A 1HXGA 2ZEUA 4LZ0A 3PYBA 5JV1F 5CG6A 5EAUA 3M01A 5I1UA 5JUZF 4GAXA 5E8LA 3PDEA 2Z4VA 4NG6A 5IL8A 5DJVF 3CP6A 3DYHA 3N5JF 3WCHA 5KSXF 3AQBB 4HD1A 4JZBA 5EASA 3TFNA 4H5DF 1WMWA 2OPNA 4F6XA 4KWDA 2Q9ZA 1WY0A 4LA6A 2F7MF 5ERMA 5C05A 1FPSA 1V4KA 4DI5A 4F6VA 4NFJF 3OYRA 4E1EA 3ICNA 3Q2ZA 1UBYA 4KVDA 5IMPA 3WJOA 3M9UA 4QXSF 5DGNF 2J1PA 3BNXA 3N1VF 4E9ZA 1WL0A 4MC0A 3WSAA 2F8CF 5DIQF 2J1OA 3WE9A 4KVIA 3RYWA 3TFVA 2Z4XA 4OMHA 4RXAA 1V4HA 2AZLA 1V4IA 3VJCA 1YYSA 3ASXA 5HN7A 4NKFA 5AHUB 5HN9A 3WCIA 5B03A 1ZW5A 4NUAA 3LLWA 3LJIA 3VJBA 3LEEA 5B00A 5B01A 3NPRA 2I19A 2E8UA 3IBAA 1JFAA 1UBVA 3V1XA 4OGUA 4RYPA 3M02A 3P5RA 2E90A 4DWBA 3KB9A 4KKMA 4E9UA 3ACWA 5E8HA 5AELA 5IVGA 3LGZB 1YHLA 1PS1A 5ILIA 2PS6A 5IKAA 3WCDA 3NPKA 3P8LA 3N45F 4DXJA 3QKCA 3KROB 2PS7A 3SAEA 3Q2QA 4LUUA 3IPIA 2Z4YA 2Z78A 5AYPA 3CKEA 2AEKA 3NRIA 1RQJA 3UCAA 4FJQA 1YV5A 5ILJA 2E4OA 2EWGA 4ZQ8A 4LTZA 3KROA 2E8XA 3KRAB 2P1CA 3WCEA 3APZA 2E92A 3OACB 3WEFA 3N0GA 4KPJA 4LLSA 5A0IA 1HM7A 3WCCA 3ZCDA 4KQUA 2AZJA 1N1ZA 4LPHF 4GA3A 2AETA 1WL2A 3KRPB 2FORA 3WJNA 3QQVA 3MAVA 4WK5A 3ACYA 4OKZA 3KRAA 3LZ9A 3OACA 3N6KF 4QPFA 5ILHA 3WC9A 2Z4ZA 2PS8A 3V66A 1WL1A 3KRPA 3S4JA 4JXYA 4LIXA 3N3DA 3M0GA 4KQ5A 4H5EF 4XQRF 3ZL6A 4XQSF 4PVYF 5IKHA 2ONHA 4JXNA 5ERNA 2F92F 5A0JA 5EATA 4KVWA 1V4EA 2Z4WA 2ZCQA 5DJPF 4PVXF 3ZOUA 3Q1OA 4XQTF 1V4JA 5JV0F 3S9VA 4Q23A 1EZFA 4RXEA 2E91A 1KIZA 3SDUA 2OA6A 3N1WF 3WEIA 3PH7A 1RTRA 1VG3A 4LXWA 5E8KA 4F62A 5IK9A 2E94A 2RAHA 4H5CF 4P0XA 1KIYA 4NKEA 4NFIF 3AQCB 5HNAA 5DHKA 3LSNA 2OGDA 2FTZA 4RXCA 3VJ9A 5ILKA 3N0FA 3P41A 3RBMA 5ILDA 3VJDA 1WKZA 3W7FA 4GP1A 3CC9A 3LVSA 4LFVF 1N23A 1RQIA 4OKMA 3LOMA 3ICMA 3EZ3A 3TS7A 1YQ7A 2Q9YA 4DHDA 3BNYA 2E8TA 2F8ZF 1N1BA 1JFGA 3WSBA 1DI1A 3KRFB 4LZ3A 5EROA 5ER8A 2J5CA 5IMNA 3EFQA 3WEJA 3P8RA 3Q30A 2DH4A 3PYAA 1WL3A 1DGPA 1N20A 4LFEA 5DJRF 3RYEA 1YYUA 3G4FA 5IL3A 2Z52A 3ZMCA 2F94F 4N1ZF 2AZKA 1YHKA 5IMIA 3KRFA 3V1VA 3N49F 1HXAA 5A0KA 1VG7A 3AQ0A 4EA0A 4LFGA 2Z7IA 4DEMF 2Q58A 4EA2A 3TC1A 2F89F 4LA5A 3LGKA 3LK5A 2ZCSA 4LLTA 5H9DA 4FP4A 5B0LA 3LMDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RXD A;  5JA0 F;  3SDQ A;  4LZC A;  3ACX A;  5IN8 A;  3KBK A;  3VJA A;  5IM1 A;  3ADZ A;  1YJ4 A;  4JZX A;  1UBW A;  2ZCR A;  1YYQ A;  3AE0 A;  2PS5 A;  3MZV A;  3WCM A;  3P5P A;  2Z7H A;  4EA1 A;  4UMJ A;  3WJK A;  2QIS A;  3WEG A;  3LG5 A;  4LTV A;  4L2X F;  3N3L F;  1YHM A;  5B0J A;  5DGM F;  3EGT A;  2ZY1 A;  3WCB A;  4KUX A;  1YYR A;  2Q80 A;  4DWG A;  4MC3 A;  4DZW A;  1VG4 A;  4P0V A;  4KQS A;  4MC8 A;  2VF6 A;  5AFX A;  5DHI A;  1YYT A;  3SDR A;  5DGS F;  4GP2 A;  2ONG A;  4KFA A;  3LDW A;  4KPD A;  3ICZ A;  3RMG A;  4P0W A;  2OPM A;  3DYG A;  1HM4 A;  3M00 A;  4LOB A;  3SDV A;  4KK2 A;  5DZ2 A;  4K10 A;  4JVJ F;  4N9U A;  2PS4 A;  3WCA A;  3WEH A;  3SDT A;  5ILY A;  2E95 A;  3TFP A;  2H8O A;  4KVY A;  2E93 A;  4JYX A;  1HX9 A;  3DYF A;  1N21 A;  3WCL A;  3N5H F;  3OAB B;  3VJE A;  3WEK A;  2ZEV A;  1UBX A;  3G4D A;  1HXC A;  5B0I A;  2Z50 A;  2ZCO A;  3KRC B;  5IK0 A;  1VG6 A;  1VG2 A;  3WCF A;  5HN8 A;  5ILZ A;  3WCG A;  5B0K A;  3OAB A;  3B7L A;  2O1O A;  3ZMB A;  5IK6 A;  3VJ8 A;  3NF2 A;  5JV2 F;  3KRC A;  3PKO A;  2F9K F;  4OMG A;  4NFK F;  3N46 F;  4LPG F;  2E8W A;  3WCJ A;  2E8V A;  1N24 A;  3ID0 A;  4RNQ A;  5B0M A;  3ICK A;  5CG5 A;  1N22 A;  2AEL A;  5DW7 A;  5B02 A;  1HXG A;  2ZEU A;  4LZ0 A;  3PYB A;  5JV1 F;  5CG6 A;  5EAU A;  3M01 A;  5I1U A;  5JUZ F;  4GAX A;  5E8L A;  3PDE A;  2Z4V A;  4NG6 A;  5IL8 A;  5DJV F;  3CP6 A;  3DYH A;  3N5J F;  3WCH A;  5KSX F;  3AQB B;  4HD1 A;  4JZB A;  5EAS A;  3TFN A;  4H5D F;  1WMW A;  2OPN A;  4F6X A;  4KWD A;  2Q9Z A;  1WY0 A;  4LA6 A;  2F7M F;  5ERM A;  5C05 A;  1FPS A;  1V4K A;  4DI5 A;  4F6V A;  4NFJ F;  3OYR A;  4E1E A;  3ICN A;  3Q2Z A;  1UBY A;  4KVD A;  5IMP A;  3WJO A;  3M9U A;  4QXS F;  5DGN F;  2J1P A;  3BNX A;  3N1V F;  4E9Z A;  1WL0 A;  4MC0 A;  3WSA A;  2F8C F;  5DIQ F;  2J1O A;  3WE9 A;  4KVI A;  3RYW A;  3TFV A;  2Z4X A;  4OMH A;  4RXA A;  1V4H A;  2AZL A;  1V4I A;  3VJC A;  1YYS A;  3ASX A;  5HN7 A;  4NKF A;  5AHU B;  5HN9 A;  3WCI A;  5B03 A;  1ZW5 A;  4NUA A;  3LLW A;  3LJI A;  3VJB A;  3LEE A;  5B00 A;  5B01 A;  3NPR A;  2I19 A;  2E8U A;  3IBA A;  1JFA A;  1UBV A;  3V1X A;  4OGU A;  4RYP A;  3M02 A;  3P5R A;  2E90 A;  4DWB A;  3KB9 A;  4KKM A;  4E9U A;  3ACW A;  5E8H A;  5AEL A;  5IVG A;  3LGZ B;  1YHL A;  1PS1 A;  5ILI A;  2PS6 A;  5IKA A;  3WCD A;  3NPK A;  3P8L A;  3N45 F;  4DXJ A;  3QKC A;  3KRO B;  2PS7 A;  3SAE A;  3Q2Q A;  4LUU A;  3IPI A;  2Z4Y A;  2Z78 A;  5AYP A;  3CKE A;  2AEK A;  3NRI A;  1RQJ A;  3UCA A;  4FJQ A;  1YV5 A;  5ILJ A;  2E4O A;  2EWG A;  4ZQ8 A;  4LTZ A;  3KRO A;  2E8X A;  3KRA B;  2P1C A;  3WCE A;  3APZ A;  2E92 A;  3OAC B;  3WEF A;  3N0G A;  4KPJ A;  4LLS A;  5A0I A;  1HM7 A;  3WCC A;  3ZCD A;  4KQU A;  2AZJ A;  1N1Z A;  4LPH F;  4GA3 A;  2AET A;  1WL2 A;  3KRP B;  2FOR A;  3WJN A;  3QQV A;  3MAV A;  4WK5 A;  3ACY A;  4OKZ A;  3KRA A;  3LZ9 A;  3OAC A;  3N6K F;  4QPF A;  5ILH A;  3WC9 A;  2Z4Z A;  2PS8 A;  3V66 A;  1WL1 A;  3KRP A;  3S4J A;  4JXY A;  4LIX A;  3N3D A;  3M0G A;  4KQ5 A;  4H5E F;  4XQR F;  3ZL6 A;  4XQS F;  4PVY F;  5IKH A;  2ONH A;  4JXN A;  5ERN A;  2F92 F;  5A0J A;  5EAT A;  4KVW A;  1V4E A;  2Z4W A;  2ZCQ A;  5DJP F;  4PVX F;  3ZOU A;  3Q1O A;  4XQT F;  1V4J A;  5JV0 F;  3S9V A;  4Q23 A;  1EZF A;  4RXE A;  2E91 A;  1KIZ A;  3SDU A;  2OA6 A;  3N1W F;  3WEI A;  3PH7 A;  1RTR A;  1VG3 A;  4LXW A;  5E8K A;  4F62 A;  5IK9 A;  2E94 A;  2RAH A;  4H5C F;  4P0X A;  1KIY A;  4NKE A;  4NFI F;  3AQC B;  5HNA A;  5DHK A;  3LSN A;  2OGD A;  2FTZ A;  4RXC A;  3VJ9 A;  5ILK A;  3N0F A;  3P41 A;  3RBM A;  5ILD A;  3VJD A;  1WKZ A;  3W7F A;  4GP1 A;  3CC9 A;  3LVS A;  4LFV F;  1N23 A;  1RQI A;  4OKM A;  3LOM A;  3ICM A;  3EZ3 A;  3TS7 A;  1YQ7 A;  2Q9Y A;  4DHD A;  3BNY A;  2E8T A;  2F8Z F;  1N1B A;  1JFG A;  3WSB A;  1DI1 A;  3KRF B;  4LZ3 A;  5ERO A;  5ER8 A;  2J5C A;  5IMN A;  3EFQ A;  3WEJ A;  3P8R A;  3Q30 A;  2DH4 A;  3PYA A;  1WL3 A;  1DGP A;  1N20 A;  4LFE A;  5DJR F;  3RYE A;  1YYU A;  3G4F A;  5IL3 A;  2Z52 A;  3ZMC A;  2F94 F;  4N1Z F;  2AZK A;  1YHK A;  5IMI A;  3KRF A;  3V1V A;  3N49 F;  1HXA A;  5A0K A;  1VG7 A;  3AQ0 A;  4EA0 A;  4LFG A;  2Z7I A;  4DEM F;  2Q58 A;  4EA2 A;  3TC1 A;  2F89 F;  4LA5 A;  3LGK A;  3LK5 A;  2ZCS A;  4LLT A;  5H9D A;  4FP4 A;  5B0L A;  3LMD A; 
#chains in the Genus database with same CATH topology
 4RXD A;  5JA0 F;  3SDQ A;  4LZC A;  3ACX A;  5IN8 A;  3KBK A;  3VJA A;  5IM1 A;  3ADZ A;  1YJ4 A;  4JZX A;  1UBW A;  2ZCR A;  1YYQ A;  3AE0 A;  2PS5 A;  3MZV A;  3WCM A;  3P5P A;  2Z7H A;  4EA1 A;  4UMJ A;  3WJK A;  2QIS A;  3WEG A;  3LG5 A;  4LTV A;  4L2X F;  3N3L F;  1YHM A;  5B0J A;  5DGM F;  3EGT A;  2ZY1 A;  3WCB A;  4KUX A;  1YYR A;  2Q80 A;  4DWG A;  4MC3 A;  4DZW A;  1VG4 A;  4P0V A;  4KQS A;  4MC8 A;  2VF6 A;  5AFX A;  5DHI A;  1YYT A;  3SDR A;  5DGS F;  4GP2 A;  2ONG A;  4KFA A;  3LDW A;  4KPD A;  3ICZ A;  3RMG A;  4P0W A;  2OPM A;  3DYG A;  1HM4 A;  3M00 A;  4LOB A;  3SDV A;  4KK2 A;  5DZ2 A;  4K10 A;  4JVJ F;  4N9U A;  2PS4 A;  3WCA A;  3WEH A;  3SDT A;  5ILY A;  2E95 A;  3TFP A;  2H8O A;  4KVY A;  2E93 A;  4JYX A;  1HX9 A;  3DYF A;  1N21 A;  3WCL A;  3N5H F;  3OAB B;  3VJE A;  3WEK A;  2ZEV A;  1UBX A;  3G4D A;  1HXC A;  5B0I A;  2Z50 A;  2ZCO A;  3KRC B;  5IK0 A;  1VG6 A;  1VG2 A;  3WCF A;  5HN8 A;  5ILZ A;  3WCG A;  5B0K A;  3OAB A;  3B7L A;  2O1O A;  3ZMB A;  5IK6 A;  3VJ8 A;  3NF2 A;  5JV2 F;  3KRC A;  3PKO A;  2F9K F;  4OMG A;  4NFK F;  3N46 F;  4LPG F;  2E8W A;  3WCJ A;  2E8V A;  1N24 A;  3ID0 A;  4RNQ A;  5B0M A;  3ICK A;  5CG5 A;  1N22 A;  2AEL A;  5DW7 A;  5B02 A;  1HXG A;  2ZEU A;  4LZ0 A;  3PYB A;  5JV1 F;  5CG6 A;  5EAU A;  3M01 A;  5I1U A;  5JUZ F;  4GAX A;  5E8L A;  3PDE A;  2Z4V A;  4NG6 A;  5IL8 A;  5DJV F;  3CP6 A;  3DYH A;  3N5J F;  3WCH A;  5KSX F;  3AQB B;  4HD1 A;  4JZB A;  5EAS A;  3TFN A;  4H5D F;  1WMW A;  2OPN A;  4F6X A;  4KWD A;  2Q9Z A;  1WY0 A;  4LA6 A;  2F7M F;  5ERM A;  5C05 A;  1FPS A;  1V4K A;  4DI5 A;  4F6V A;  4NFJ F;  3OYR A;  4E1E A;  3ICN A;  3Q2Z A;  1UBY A;  4KVD A;  5IMP A;  3WJO A;  3M9U A;  4QXS F;  5DGN F;  2J1P A;  3BNX A;  3N1V F;  4E9Z A;  1WL0 A;  4MC0 A;  3WSA A;  2F8C F;  5DIQ F;  2J1O A;  3WE9 A;  4KVI A;  3RYW A;  3TFV A;  2Z4X A;  4OMH A;  4RXA A;  1V4H A;  2AZL A;  1V4I A;  3VJC A;  1YYS A;  3ASX A;  5HN7 A;  4NKF A;  5AHU B;  5HN9 A;  3WCI A;  5B03 A;  1ZW5 A;  4NUA A;  3LLW A;  3LJI A;  3VJB A;  3LEE A;  5B00 A;  5B01 A;  3NPR A;  2I19 A;  2E8U A;  3IBA A;  1JFA A;  1UBV A;  3V1X A;  4OGU A;  4RYP A;  3M02 A;  3P5R A;  2E90 A;  4DWB A;  3KB9 A;  4KKM A;  4E9U A;  3ACW A;  5E8H A;  5AEL A;  5IVG A;  3LGZ B;  1YHL A;  1PS1 A;  5ILI A;  2PS6 A;  5IKA A;  3WCD A;  3NPK A;  3P8L A;  3N45 F;  4DXJ A;  3QKC A;  3KRO B;  2PS7 A;  3SAE A;  3Q2Q A;  4LUU A;  3IPI A;  2Z4Y A;  2Z78 A;  5AYP A;  3CKE A;  2AEK A;  3NRI A;  1RQJ A;  3UCA A;  4FJQ A;  1YV5 A;  5ILJ A;  2E4O A;  2EWG A;  4ZQ8 A;  4LTZ A;  3KRO A;  2E8X A;  3KRA B;  2P1C A;  3WCE A;  3APZ A;  2E92 A;  3OAC B;  3WEF A;  3N0G A;  4KPJ A;  4LLS A;  5A0I A;  1HM7 A;  3WCC A;  3ZCD A;  4KQU A;  2AZJ A;  1N1Z A;  4LPH F;  4GA3 A;  2AET A;  1WL2 A;  3KRP B;  2FOR A;  3WJN A;  3QQV A;  3MAV A;  4WK5 A;  3ACY A;  4OKZ A;  3KRA A;  3LZ9 A;  3OAC A;  3N6K F;  4QPF A;  5ILH A;  3WC9 A;  2Z4Z A;  2PS8 A;  3V66 A;  1WL1 A;  3KRP A;  3S4J A;  4JXY A;  4LIX A;  3N3D A;  3M0G A;  4KQ5 A;  4H5E F;  4XQR F;  3ZL6 A;  4XQS F;  4PVY F;  5IKH A;  2ONH A;  4JXN A;  5ERN A;  2F92 F;  5A0J A;  5EAT A;  4KVW A;  1V4E A;  2Z4W A;  2ZCQ A;  5DJP F;  4PVX F;  3ZOU A;  3Q1O A;  4XQT F;  1V4J A;  5JV0 F;  3S9V A;  4Q23 A;  1EZF A;  4RXE A;  2E91 A;  1KIZ A;  3SDU A;  2OA6 A;  3N1W F;  3WEI A;  3PH7 A;  1RTR A;  1VG3 A;  4LXW A;  5E8K A;  4F62 A;  5IK9 A;  2E94 A;  2RAH A;  4H5C F;  4P0X A;  1KIY A;  4NKE A;  4NFI F;  3AQC B;  5HNA A;  5DHK A;  3LSN A;  2OGD A;  2FTZ A;  4RXC A;  3VJ9 A;  5ILK A;  3N0F A;  3P41 A;  3RBM A;  5ILD A;  3VJD A;  1WKZ A;  3W7F A;  4GP1 A;  3CC9 A;  3LVS A;  4LFV F;  1N23 A;  1RQI A;  4OKM A;  3LOM A;  3ICM A;  3EZ3 A;  3TS7 A;  1YQ7 A;  2Q9Y A;  4DHD A;  3BNY A;  2E8T A;  2F8Z F;  1N1B A;  1JFG A;  3WSB A;  1DI1 A;  3KRF B;  4LZ3 A;  5ERO A;  5ER8 A;  2J5C A;  5IMN A;  3EFQ A;  3WEJ A;  3P8R A;  3Q30 A;  2DH4 A;  3PYA A;  1WL3 A;  1DGP A;  1N20 A;  4LFE A;  5DJR F;  3RYE A;  1YYU A;  3G4F A;  5IL3 A;  2Z52 A;  3ZMC A;  2F94 F;  4N1Z F;  2AZK A;  1YHK A;  5IMI A;  3KRF A;  3V1V A;  3N49 F;  1HXA A;  5A0K A;  1VG7 A;  3AQ0 A;  4EA0 A;  4LFG A;  2Z7I A;  4DEM F;  2Q58 A;  4EA2 A;  3TC1 A;  2F89 F;  4LA5 A;  3LGK A;  3LK5 A;  2ZCS A;  4LLT A;  5H9D A;  4FP4 A;  5B0L A;  3LMD A; 
#chains in the Genus database with same CATH homology
 4RXD A;  5JA0 F;  3SDQ A;  4LZC A;  3ACX A;  5IN8 A;  3KBK A;  3VJA A;  5IM1 A;  3ADZ A;  1YJ4 A;  4JZX A;  1UBW A;  2ZCR A;  1YYQ A;  3AE0 A;  2PS5 A;  3MZV A;  3WCM A;  3P5P A;  2Z7H A;  4EA1 A;  4UMJ A;  3WJK A;  2QIS A;  3WEG A;  3LG5 A;  4LTV A;  4L2X F;  3N3L F;  1YHM A;  5B0J A;  5DGM F;  3EGT A;  2ZY1 A;  3WCB A;  4KUX A;  1YYR A;  2Q80 A;  4DWG A;  4MC3 A;  4DZW A;  1VG4 A;  4P0V A;  4KQS A;  4MC8 A;  2VF6 A;  5AFX A;  5DHI A;  1YYT A;  3SDR A;  5DGS F;  4GP2 A;  2ONG A;  4KFA A;  3LDW A;  4KPD A;  3ICZ A;  3RMG A;  4P0W A;  2OPM A;  3DYG A;  1HM4 A;  3M00 A;  4LOB A;  3SDV A;  4KK2 A;  5DZ2 A;  4K10 A;  4JVJ F;  4N9U A;  2PS4 A;  3WCA A;  3WEH A;  3SDT A;  5ILY A;  2E95 A;  3TFP A;  2H8O A;  4KVY A;  2E93 A;  4JYX A;  1HX9 A;  3DYF A;  1N21 A;  3WCL A;  3N5H F;  3OAB B;  3VJE A;  3WEK A;  2ZEV A;  1UBX A;  3G4D A;  1HXC A;  5B0I A;  2Z50 A;  2ZCO A;  3KRC B;  5IK0 A;  1VG6 A;  1VG2 A;  3WCF A;  5HN8 A;  5ILZ A;  3WCG A;  5B0K A;  3OAB A;  3B7L A;  2O1O A;  3ZMB A;  5IK6 A;  3VJ8 A;  3NF2 A;  5JV2 F;  3KRC A;  3PKO A;  2F9K F;  4OMG A;  4NFK F;  3N46 F;  4LPG F;  2E8W A;  3WCJ A;  2E8V A;  1N24 A;  3ID0 A;  4RNQ A;  5B0M A;  3ICK A;  5CG5 A;  1N22 A;  2AEL A;  5DW7 A;  5B02 A;  1HXG A;  2ZEU A;  4LZ0 A;  3PYB A;  5JV1 F;  5CG6 A;  5EAU A;  3M01 A;  5I1U A;  5JUZ F;  4GAX A;  5E8L A;  3PDE A;  2Z4V A;  4NG6 A;  5IL8 A;  5DJV F;  3CP6 A;  3DYH A;  3N5J F;  3WCH A;  5KSX F;  3AQB B;  4HD1 A;  4JZB A;  5EAS A;  3TFN A;  4H5D F;  1WMW A;  2OPN A;  4F6X A;  4KWD A;  2Q9Z A;  1WY0 A;  4LA6 A;  2F7M F;  5ERM A;  5C05 A;  1FPS A;  1V4K A;  4DI5 A;  4F6V A;  4NFJ F;  3OYR A;  4E1E A;  3ICN A;  3Q2Z A;  1UBY A;  4KVD A;  5IMP A;  3WJO A;  3M9U A;  4QXS F;  5DGN F;  2J1P A;  3BNX A;  3N1V F;  4E9Z A;  1WL0 A;  4MC0 A;  3WSA A;  2F8C F;  5DIQ F;  2J1O A;  3WE9 A;  4KVI A;  3RYW A;  3TFV A;  2Z4X A;  4OMH A;  4RXA A;  1V4H A;  2AZL A;  1V4I A;  3VJC A;  1YYS A;  3ASX A;  5HN7 A;  4NKF A;  5AHU B;  5HN9 A;  3WCI A;  5B03 A;  1ZW5 A;  4NUA A;  3LLW A;  3LJI A;  3VJB A;  3LEE A;  5B00 A;  5B01 A;  3NPR A;  2I19 A;  2E8U A;  3IBA A;  1JFA A;  1UBV A;  3V1X A;  4OGU A;  4RYP A;  3M02 A;  3P5R A;  2E90 A;  4DWB A;  3KB9 A;  4KKM A;  4E9U A;  3ACW A;  5E8H A;  5AEL A;  5IVG A;  3LGZ B;  1YHL A;  1PS1 A;  5ILI A;  2PS6 A;  5IKA A;  3WCD A;  3NPK A;  3P8L A;  3N45 F;  4DXJ A;  3QKC A;  3KRO B;  2PS7 A;  3SAE A;  3Q2Q A;  4LUU A;  3IPI A;  2Z4Y A;  2Z78 A;  5AYP A;  3CKE A;  2AEK A;  3NRI A;  1RQJ A;  3UCA A;  4FJQ A;  1YV5 A;  5ILJ A;  2E4O A;  2EWG A;  4ZQ8 A;  4LTZ A;  3KRO A;  2E8X A;  3KRA B;  2P1C A;  3WCE A;  3APZ A;  2E92 A;  3OAC B;  3WEF A;  3N0G A;  4KPJ A;  4LLS A;  5A0I A;  1HM7 A;  3WCC A;  3ZCD A;  4KQU A;  2AZJ A;  1N1Z A;  4LPH F;  4GA3 A;  2AET A;  1WL2 A;  3KRP B;  2FOR A;  3WJN A;  3QQV A;  3MAV A;  4WK5 A;  3ACY A;  4OKZ A;  3KRA A;  3LZ9 A;  3OAC A;  3N6K F;  4QPF A;  5ILH A;  3WC9 A;  2Z4Z A;  2PS8 A;  3V66 A;  1WL1 A;  3KRP A;  3S4J A;  4JXY A;  4LIX A;  3N3D A;  3M0G A;  4KQ5 A;  4H5E F;  4XQR F;  3ZL6 A;  4XQS F;  4PVY F;  5IKH A;  2ONH A;  4JXN A;  5ERN A;  2F92 F;  5A0J A;  5EAT A;  4KVW A;  1V4E A;  2Z4W A;  2ZCQ A;  5DJP F;  4PVX F;  3ZOU A;  3Q1O A;  4XQT F;  1V4J A;  5JV0 F;  3S9V A;  4Q23 A;  1EZF A;  4RXE A;  2E91 A;  1KIZ A;  3SDU A;  2OA6 A;  3N1W F;  3WEI A;  3PH7 A;  1RTR A;  1VG3 A;  4LXW A;  5E8K A;  4F62 A;  5IK9 A;  2E94 A;  2RAH A;  4H5C F;  4P0X A;  1KIY A;  4NKE A;  4NFI F;  3AQC B;  5HNA A;  5DHK A;  3LSN A;  2OGD A;  2FTZ A;  4RXC A;  3VJ9 A;  5ILK A;  3N0F A;  3P41 A;  3RBM A;  5ILD A;  3VJD A;  1WKZ A;  3W7F A;  4GP1 A;  3CC9 A;  3LVS A;  4LFV F;  1N23 A;  1RQI A;  4OKM A;  3LOM A;  3ICM A;  3EZ3 A;  3TS7 A;  1YQ7 A;  2Q9Y A;  4DHD A;  3BNY A;  2E8T A;  2F8Z F;  1N1B A;  1JFG A;  3WSB A;  1DI1 A;  3KRF B;  4LZ3 A;  5ERO A;  5ER8 A;  2J5C A;  5IMN A;  3EFQ A;  3WEJ A;  3P8R A;  3Q30 A;  2DH4 A;  3PYA A;  1WL3 A;  1DGP A;  1N20 A;  4LFE A;  5DJR F;  3RYE A;  1YYU A;  3G4F A;  5IL3 A;  2Z52 A;  3ZMC A;  2F94 F;  4N1Z F;  2AZK A;  1YHK A;  5IMI A;  3KRF A;  3V1V A;  3N49 F;  1HXA A;  5A0K A;  1VG7 A;  3AQ0 A;  4EA0 A;  4LFG A;  2Z7I A;  4DEM F;  2Q58 A;  4EA2 A;  3TC1 A;  2F89 F;  4LA5 A;  3LGK A;  3LK5 A;  2ZCS A;  4LLT A;  5H9D A;  4FP4 A;  5B0L A;  3LMD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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