3VJ9A

Crystal structure of the human squalene synthase
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 147
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vj9A00
1V4EA 3S9VA 4WK5A 3M9UA 2ZY1A 2AEKA 2DH4A 5DIQF 1YYTA 4LA6A 4GP2A 4DHDA 2E8WA 2Z4WA 3M01A 3P5PA 5DGSF 3WCEA 1VG6A 3LDWA 3P5RA 5B0KA 2ZCOA 1N1ZA 5CG5A 4OMGA 5B0LA 4JVJF 3EZ3A 5DHIA 3WCFA 3KRPB 3APZA 2AZKA 4GP1A 1V4KA 3G4FA 2FORA 4GA3A 3SAEA 3LOMA 3VJBA 2PS5A 4KVYA 4NFJF 4NUAA 3WCJA 3LVSA 4JZBA 5IL3A 3NF2A 4EA1A 5DJRF 4N9UA 3ID0A 1JFAA 3WCDA 2FTZA 3DYGA 1HM4A 5DW7A 5AFXA 3KRFA 2Z7HA 3Q1OA 5JUZF 2Z50A 3BNXA 3N6KF 4LTZA 1WMWA 3WEGA 3ZMCA 3N1VF 4JXNA 1N24A 1KIZA 3WCBA 1RTRA 2Q80A 4JZXA 3KRAA 1N1BA 3LSNA 2Z4YA 5IMNA 2Z4VA 3BNYA 5B03A 4P0WA 3N1WF 3LZ9A 3N0GA 1YYRA 1YYUA 5ERNA 1YYQA 3WCIA 3LGKA 3WEKA 5EAUA 5B01A 1WL0A 3DYFA 2PS4A 4LA5A 4LLSA 2Q9ZA 3V1VA 1HX9A 2OA6A 3WCLA 5HNAA 4EA2A 3WCGA 3TFVA 3KB9A 2OPNA 4EA0A 4LUUA 3PYBA 1RQIA 3WCAA 5AYPA 3ICNA 5HN9A 3KRAB 4DI5A 3TFNA 2Z4XA 5HN7A 5E8KA 1N21A 1EZFA 4F6VA 2O1OA 4ZQ8A 3WEFA 5I1UA 1HXGA 4LZ0A 3LGZB 2F8ZF 1VG4A 4LZ3A 2F92F 3N46F 2E8XA 3WE9A 5JV1F 5ILJA 3WSAA 5ILIA 3AQ0A 3KROB 4DWGA 3LK5A 5IK9A 3SDVA 5DHKA 2Z52A 2ZEUA 3ACYA 4H5DF 2F94F 1DI1A 1UBXA 4JYXA 4RXDA 3ICKA 1DGPA 1YHLA 2QISA 2E91A 1N22A 3EGTA 4KFAA 5B0MA 3LEEA 1WY0A 3NPKA 3WJOA 4NFIF 3N0FA 1UBVA 5B02A 2F7MF 5ERMA 2Z7IA 3ICMA 3LJIA 1V4IA 2E4OA 3S4JA 5KSXF 4RYPA 2F9KF 2E90A 2E8VA 2E8UA 3IPIA 4HD1A 1WKZA 4K10A 4LPGF 5IK0A 2P1CA 3MZVA 5ILYA 1WL2A 4XQSF 3KRCB 4LTVA 2AELA 4MC0A 5ER8A 4LZCA 5B0JA 4Q23A 1UBYA 1ZW5A 2AZLA 4F6XA 2J1PA 2ZCQA 1YQ7A 2I19A 5B0IA 5ILKA 4QPFA 3ICZA 1N20A 4KQ5A 3QQVA 4LLTA 1FPSA 3NRIA 4RXAA 3SDTA 3PH7A 2PS8A 3KROA 3N5HF 4LFVF 5B00A 4KK2A 3ZOUA 4H5CF 4LFEA 3WEIA 4P0VA 4KUXA 3P41A 4RNQA 5DGMF 2PS7A 5IL8A 3VJAA 3VJ9A 3RYEA 3NPRA 3EFQA 5A0JA 4FJQA 3RMGA 1VG7A 5IK6A 1YHKA 3AQBB 3V1XA 4KKMA 5DZ2A 3SDRA 2Q58A 3Q2QA 3V66A 3OABB 3ZCDA 2Q9YA 3M0GA 2AZJA 3N49F 3SDUA 5ILDA 4KQSA 3ADZA 5H9DA 4GAXA 4NG6A 5JV0F 3WJKA 4OKMA 4NKEA 5DGNF 2Z4ZA 3N3LF 2ONGA 5IMIA 3M00A 3P8LA 5ILHA 3WEHA 1PS1A 1V4HA 4RXEA 4KPJA 2E95A 2ZCRA 2E8TA 3LG5A 3OYRA 5IKHA 5AELA 3ACWA 1HXAA 2ZCSA 4MC8A 4LFGA 3ACXA 2ZEVA 3KRCA 3PKOA 5A0KA 3CC9A 1N23A 3PDEA 2OPMA 1VG3A 4DEMF 3B7LA 4UMJA 2H8OA 5A0IA 2PS6A 1V4JA 3UCAA 1JFGA 2OGDA 4JXYA 3WCMA 4KPDA 3WC9A 3G4DA 3WSBA 1RQJA 5HN8A 4KWDA 4E1EA 3AQCB 4E9UA 3RBMA 3IBAA 3OACA 4KVDA 5IN8A 4E9ZA 3RYWA 3VJ8A 3KBKA 3CKEA 4LIXA 2VF6A 2E92A 4FP4A 1KIYA 1HM7A 2RAHA 3MAVA 4LXWA 4KVWA 5EATA 4NKFA 3Q2ZA 4LOBA 3OABA 4PVYF 5DJVF 3WCCA 3WEJA 2E94A 4DXJA 4H5EF 4P0XA 3WCHA 4RXCA 4PVXF 4DZWA 1YV5A 1HXCA 3N45F 3M02A 4XQTF 3ASXA 1VG2A 4F62A 3N3DA 3VJEA 3OACB 2J5CA 3P8RA 5EROA 4OGUA 3LLWA 5IM1A 4OMHA 1YYSA 5JV2F 1WL3A 4KVIA 4QXSF 5JA0F 3N5JF 4OKZA 2AETA 2F89F 3DYHA 3PYAA 4N1ZF 5IVGA 3KRFB 3W7FA 2EWGA 5IMPA 1UBWA 3AE0A 5C05A 3LMDA 3QKCA 2ONHA 3TFPA 2Z78A 4LPHF 3TC1A 3VJCA 1YHMA 3Q30A 5AHUB 3WJNA 3ZL6A 1WL1A 2E93A 5DJPF 3TS7A 5EASA 2J1OA 4DWBA 3KRPA 4KQUA 1YJ4A 3CP6A 5E8LA 5IKAA 4NFKF 3VJDA 3ZMBA 2F8CF 5ILZA 5E8HA 3SDQA 5CG6A 4L2XF 4XQRF 4MC3A
chains in the Genus database with same CATH superfamily
1V4EA 3S9VA 4WK5A 3M9UA 2ZY1A 2AEKA 2DH4A 5DIQF 1YYTA 4LA6A 4GP2A 4DHDA 2E8WA 2Z4WA 3M01A 3P5PA 5DGSF 3WCEA 1VG6A 3LDWA 3P5RA 5B0KA 2ZCOA 1N1ZA 5CG5A 4OMGA 5B0LA 4JVJF 3EZ3A 5DHIA 3WCFA 3KRPB 3APZA 2AZKA 4GP1A 1V4KA 3G4FA 2FORA 4GA3A 3SAEA 3LOMA 3VJBA 2PS5A 4KVYA 4NFJF 4NUAA 3WCJA 3LVSA 4JZBA 5IL3A 3NF2A 4EA1A 5DJRF 4N9UA 3ID0A 1JFAA 3WCDA 2FTZA 3DYGA 1HM4A 5DW7A 5AFXA 3KRFA 2Z7HA 3Q1OA 5JUZF 2Z50A 3BNXA 3N6KF 4LTZA 1WMWA 3WEGA 3ZMCA 3N1VF 4JXNA 1N24A 1KIZA 3WCBA 1RTRA 2Q80A 4JZXA 3KRAA 1N1BA 3LSNA 2Z4YA 5IMNA 2Z4VA 3BNYA 5B03A 4P0WA 3N1WF 3LZ9A 3N0GA 1YYRA 1YYUA 5ERNA 1YYQA 3WCIA 3LGKA 3WEKA 5EAUA 5B01A 1WL0A 3DYFA 2PS4A 4LA5A 4LLSA 2Q9ZA 3V1VA 1HX9A 2OA6A 3WCLA 5HNAA 4EA2A 3WCGA 3TFVA 3KB9A 2OPNA 4EA0A 4LUUA 3PYBA 1RQIA 3WCAA 5AYPA 3ICNA 5HN9A 3KRAB 4DI5A 3TFNA 2Z4XA 5HN7A 5E8KA 1N21A 1EZFA 4F6VA 2O1OA 4ZQ8A 3WEFA 5I1UA 1HXGA 4LZ0A 3LGZB 2F8ZF 1VG4A 4LZ3A 2F92F 3N46F 2E8XA 3WE9A 5JV1F 5ILJA 3WSAA 5ILIA 3AQ0A 3KROB 4DWGA 3LK5A 5IK9A 3SDVA 5DHKA 2Z52A 2ZEUA 3ACYA 4H5DF 2F94F 1DI1A 1UBXA 4JYXA 4RXDA 3ICKA 1DGPA 1YHLA 2QISA 2E91A 1N22A 3EGTA 4KFAA 5B0MA 3LEEA 1WY0A 3NPKA 3WJOA 4NFIF 3N0FA 1UBVA 5B02A 2F7MF 5ERMA 2Z7IA 3ICMA 3LJIA 1V4IA 2E4OA 3S4JA 5KSXF 4RYPA 2F9KF 2E90A 2E8VA 2E8UA 3IPIA 4HD1A 1WKZA 4K10A 4LPGF 5IK0A 2P1CA 3MZVA 5ILYA 1WL2A 4XQSF 3KRCB 4LTVA 2AELA 4MC0A 5ER8A 4LZCA 5B0JA 4Q23A 1UBYA 1ZW5A 2AZLA 4F6XA 2J1PA 2ZCQA 1YQ7A 2I19A 5B0IA 5ILKA 4QPFA 3ICZA 1N20A 4KQ5A 3QQVA 4LLTA 1FPSA 3NRIA 4RXAA 3SDTA 3PH7A 2PS8A 3KROA 3N5HF 4LFVF 5B00A 4KK2A 3ZOUA 4H5CF 4LFEA 3WEIA 4P0VA 4KUXA 3P41A 4RNQA 5DGMF 2PS7A 5IL8A 3VJAA 3VJ9A 3RYEA 3NPRA 3EFQA 5A0JA 4FJQA 3RMGA 1VG7A 5IK6A 1YHKA 3AQBB 3V1XA 4KKMA 5DZ2A 3SDRA 2Q58A 3Q2QA 3V66A 3OABB 3ZCDA 2Q9YA 3M0GA 2AZJA 3N49F 3SDUA 5ILDA 4KQSA 3ADZA 5H9DA 4GAXA 4NG6A 5JV0F 3WJKA 4OKMA 4NKEA 5DGNF 2Z4ZA 3N3LF 2ONGA 5IMIA 3M00A 3P8LA 5ILHA 3WEHA 1PS1A 1V4HA 4RXEA 4KPJA 2E95A 2ZCRA 2E8TA 3LG5A 3OYRA 5IKHA 5AELA 3ACWA 1HXAA 2ZCSA 4MC8A 4LFGA 3ACXA 2ZEVA 3KRCA 3PKOA 5A0KA 3CC9A 1N23A 3PDEA 2OPMA 1VG3A 4DEMF 3B7LA 4UMJA 2H8OA 5A0IA 2PS6A 1V4JA 3UCAA 1JFGA 2OGDA 4JXYA 3WCMA 4KPDA 3WC9A 3G4DA 3WSBA 1RQJA 5HN8A 4KWDA 4E1EA 3AQCB 4E9UA 3RBMA 3IBAA 3OACA 4KVDA 5IN8A 4E9ZA 3RYWA 3VJ8A 3KBKA 3CKEA 4LIXA 2VF6A 2E92A 4FP4A 1KIYA 1HM7A 2RAHA 3MAVA 4LXWA 4KVWA 5EATA 4NKFA 3Q2ZA 4LOBA 3OABA 4PVYF 5DJVF 3WCCA 3WEJA 2E94A 4DXJA 4H5EF 4P0XA 3WCHA 4RXCA 4PVXF 4DZWA 1YV5A 1HXCA 3N45F 3M02A 4XQTF 3ASXA 1VG2A 4F62A 3N3DA 3VJEA 3OACB 2J5CA 3P8RA 5EROA 4OGUA 3LLWA 5IM1A 4OMHA 1YYSA 5JV2F 1WL3A 4KVIA 4QXSF 5JA0F 3N5JF 4OKZA 2AETA 2F89F 3DYHA 3PYAA 4N1ZF 5IVGA 3KRFB 3W7FA 2EWGA 5IMPA 1UBWA 3AE0A 5C05A 3LMDA 3QKCA 2ONHA 3TFPA 2Z78A 4LPHF 3TC1A 3VJCA 1YHMA 3Q30A 5AHUB 3WJNA 3ZL6A 1WL1A 2E93A 5DJPF 3TS7A 5EASA 2J1OA 4DWBA 3KRPA 4KQUA 1YJ4A 3CP6A 5E8LA 5IKAA 4NFKF 3VJDA 3ZMBA 2F8CF 5ILZA 5E8HA 3SDQA 5CG6A 4L2XF 4XQRF 4MC3A
chains in the Genus database with same CATH topology
1V4EA 3S9VA 4WK5A 3M9UA 2ZY1A 2AEKA 2DH4A 5DIQF 1YYTA 4LA6A 4GP2A 4DHDA 2E8WA 2Z4WA 3M01A 3P5PA 5DGSF 3WCEA 1VG6A 3LDWA 3P5RA 5B0KA 2ZCOA 1N1ZA 5CG5A 4OMGA 5B0LA 4JVJF 3EZ3A 5DHIA 3WCFA 3KRPB 3APZA 2AZKA 4GP1A 1V4KA 3G4FA 2FORA 4GA3A 3SAEA 3LOMA 3VJBA 2PS5A 4KVYA 4NFJF 4NUAA 3WCJA 3LVSA 4JZBA 5IL3A 3NF2A 4EA1A 5DJRF 4N9UA 3ID0A 1JFAA 3WCDA 2FTZA 3DYGA 1HM4A 5DW7A 5AFXA 3KRFA 2Z7HA 3Q1OA 5JUZF 2Z50A 3BNXA 3N6KF 4LTZA 1WMWA 3WEGA 3ZMCA 3N1VF 4JXNA 1N24A 1KIZA 3WCBA 1RTRA 2Q80A 4JZXA 3KRAA 1N1BA 3LSNA 2Z4YA 5IMNA 2Z4VA 3BNYA 5B03A 4P0WA 3N1WF 3LZ9A 3N0GA 1YYRA 1YYUA 5ERNA 1YYQA 3WCIA 3LGKA 3WEKA 5EAUA 5B01A 1WL0A 3DYFA 2PS4A 4LA5A 4LLSA 2Q9ZA 3V1VA 1HX9A 2OA6A 3WCLA 5HNAA 4EA2A 3WCGA 3TFVA 3KB9A 2OPNA 4EA0A 4LUUA 3PYBA 1RQIA 3WCAA 5AYPA 3ICNA 5HN9A 3KRAB 4DI5A 3TFNA 2Z4XA 5HN7A 5E8KA 1N21A 1EZFA 4F6VA 2O1OA 4ZQ8A 3WEFA 5I1UA 1HXGA 4LZ0A 3LGZB 2F8ZF 1VG4A 4LZ3A 2F92F 3N46F 2E8XA 3WE9A 5JV1F 5ILJA 3WSAA 5ILIA 3AQ0A 3KROB 4DWGA 3LK5A 5IK9A 3SDVA 5DHKA 2Z52A 2ZEUA 3ACYA 4H5DF 2F94F 1DI1A 1UBXA 4JYXA 4RXDA 3ICKA 1DGPA 1YHLA 2QISA 2E91A 1N22A 3EGTA 4KFAA 5B0MA 3LEEA 1WY0A 3NPKA 3WJOA 4NFIF 3N0FA 1UBVA 5B02A 2F7MF 5ERMA 2Z7IA 3ICMA 3LJIA 1V4IA 2E4OA 3S4JA 5KSXF 4RYPA 2F9KF 2E90A 2E8VA 2E8UA 3IPIA 4HD1A 1WKZA 4K10A 4LPGF 5IK0A 2P1CA 3MZVA 5ILYA 1WL2A 4XQSF 3KRCB 4LTVA 2AELA 4MC0A 5ER8A 4LZCA 5B0JA 4Q23A 1UBYA 1ZW5A 2AZLA 4F6XA 2J1PA 2ZCQA 1YQ7A 2I19A 5B0IA 5ILKA 4QPFA 3ICZA 1N20A 4KQ5A 3QQVA 4LLTA 1FPSA 3NRIA 4RXAA 3SDTA 3PH7A 2PS8A 3KROA 3N5HF 4LFVF 5B00A 4KK2A 3ZOUA 4H5CF 4LFEA 3WEIA 4P0VA 4KUXA 3P41A 4RNQA 5DGMF 2PS7A 5IL8A 3VJAA 3VJ9A 3RYEA 3NPRA 3EFQA 5A0JA 4FJQA 3RMGA 1VG7A 5IK6A 1YHKA 3AQBB 3V1XA 4KKMA 5DZ2A 3SDRA 2Q58A 3Q2QA 3V66A 3OABB 3ZCDA 2Q9YA 3M0GA 2AZJA 3N49F 3SDUA 5ILDA 4KQSA 3ADZA 5H9DA 4GAXA 4NG6A 5JV0F 3WJKA 4OKMA 4NKEA 5DGNF 2Z4ZA 3N3LF 2ONGA 5IMIA 3M00A 3P8LA 5ILHA 3WEHA 1PS1A 1V4HA 4RXEA 4KPJA 2E95A 2ZCRA 2E8TA 3LG5A 3OYRA 5IKHA 5AELA 3ACWA 1HXAA 2ZCSA 4MC8A 4LFGA 3ACXA 2ZEVA 3KRCA 3PKOA 5A0KA 3CC9A 1N23A 3PDEA 2OPMA 1VG3A 4DEMF 3B7LA 4UMJA 2H8OA 5A0IA 2PS6A 1V4JA 3UCAA 1JFGA 2OGDA 4JXYA 3WCMA 4KPDA 3WC9A 3G4DA 3WSBA 1RQJA 5HN8A 4KWDA 4E1EA 3AQCB 4E9UA 3RBMA 3IBAA 3OACA 4KVDA 5IN8A 4E9ZA 3RYWA 3VJ8A 3KBKA 3CKEA 4LIXA 2VF6A 2E92A 4FP4A 1KIYA 1HM7A 2RAHA 3MAVA 4LXWA 4KVWA 5EATA 4NKFA 3Q2ZA 4LOBA 3OABA 4PVYF 5DJVF 3WCCA 3WEJA 2E94A 4DXJA 4H5EF 4P0XA 3WCHA 4RXCA 4PVXF 4DZWA 1YV5A 1HXCA 3N45F 3M02A 4XQTF 3ASXA 1VG2A 4F62A 3N3DA 3VJEA 3OACB 2J5CA 3P8RA 5EROA 4OGUA 3LLWA 5IM1A 4OMHA 1YYSA 5JV2F 1WL3A 4KVIA 4QXSF 5JA0F 3N5JF 4OKZA 2AETA 2F89F 3DYHA 3PYAA 4N1ZF 5IVGA 3KRFB 3W7FA 2EWGA 5IMPA 1UBWA 3AE0A 5C05A 3LMDA 3QKCA 2ONHA 3TFPA 2Z78A 4LPHF 3TC1A 3VJCA 1YHMA 3Q30A 5AHUB 3WJNA 3ZL6A 1WL1A 2E93A 5DJPF 3TS7A 5EASA 2J1OA 4DWBA 3KRPA 4KQUA 1YJ4A 3CP6A 5E8LA 5IKAA 4NFKF 3VJDA 3ZMBA 2F8CF 5ILZA 5E8HA 3SDQA 5CG6A 4L2XF 4XQRF 4MC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V4E A;  3S9V A;  4WK5 A;  3M9U A;  2ZY1 A;  2AEK A;  2DH4 A;  5DIQ F;  1YYT A;  4LA6 A;  4GP2 A;  4DHD A;  2E8W A;  2Z4W A;  3M01 A;  3P5P A;  5DGS F;  3WCE A;  1VG6 A;  3LDW A;  3P5R A;  5B0K A;  2ZCO A;  1N1Z A;  5CG5 A;  4OMG A;  5B0L A;  4JVJ F;  3EZ3 A;  5DHI A;  3WCF A;  3KRP B;  3APZ A;  2AZK A;  4GP1 A;  1V4K A;  3G4F A;  2FOR A;  4GA3 A;  3SAE A;  3LOM A;  3VJB A;  2PS5 A;  4KVY A;  4NFJ F;  4NUA A;  3WCJ A;  3LVS A;  4JZB A;  5IL3 A;  3NF2 A;  4EA1 A;  5DJR F;  4N9U A;  3ID0 A;  1JFA A;  3WCD A;  2FTZ A;  3DYG A;  1HM4 A;  5DW7 A;  5AFX A;  3KRF A;  2Z7H A;  3Q1O A;  5JUZ F;  2Z50 A;  3BNX A;  3N6K F;  4LTZ A;  1WMW A;  3WEG A;  3ZMC A;  3N1V F;  4JXN A;  1N24 A;  1KIZ A;  3WCB A;  1RTR A;  2Q80 A;  4JZX A;  3KRA A;  1N1B A;  3LSN A;  2Z4Y A;  5IMN A;  2Z4V A;  3BNY A;  5B03 A;  4P0W A;  3N1W F;  3LZ9 A;  3N0G A;  1YYR A;  1YYU A;  5ERN A;  1YYQ A;  3WCI A;  3LGK A;  3WEK A;  5EAU A;  5B01 A;  1WL0 A;  3DYF A;  2PS4 A;  4LA5 A;  4LLS A;  2Q9Z A;  3V1V A;  1HX9 A;  2OA6 A;  3WCL A;  5HNA A;  4EA2 A;  3WCG A;  3TFV A;  3KB9 A;  2OPN A;  4EA0 A;  4LUU A;  3PYB A;  1RQI A;  3WCA A;  5AYP A;  3ICN A;  5HN9 A;  3KRA B;  4DI5 A;  3TFN A;  2Z4X A;  5HN7 A;  5E8K A;  1N21 A;  1EZF A;  4F6V A;  2O1O A;  4ZQ8 A;  3WEF A;  5I1U A;  1HXG A;  4LZ0 A;  3LGZ B;  2F8Z F;  1VG4 A;  4LZ3 A;  2F92 F;  3N46 F;  2E8X A;  3WE9 A;  5JV1 F;  5ILJ A;  3WSA A;  5ILI A;  3AQ0 A;  3KRO B;  4DWG A;  3LK5 A;  5IK9 A;  3SDV A;  5DHK A;  2Z52 A;  2ZEU A;  3ACY A;  4H5D F;  2F94 F;  1DI1 A;  1UBX A;  4JYX A;  4RXD A;  3ICK A;  1DGP A;  1YHL A;  2QIS A;  2E91 A;  1N22 A;  3EGT A;  4KFA A;  5B0M A;  3LEE A;  1WY0 A;  3NPK A;  3WJO A;  4NFI F;  3N0F A;  1UBV A;  5B02 A;  2F7M F;  5ERM A;  2Z7I A;  3ICM A;  3LJI A;  1V4I A;  2E4O A;  3S4J A;  5KSX F;  4RYP A;  2F9K F;  2E90 A;  2E8V A;  2E8U A;  3IPI A;  4HD1 A;  1WKZ A;  4K10 A;  4LPG F;  5IK0 A;  2P1C A;  3MZV A;  5ILY A;  1WL2 A;  4XQS F;  3KRC B;  4LTV A;  2AEL A;  4MC0 A;  5ER8 A;  4LZC A;  5B0J A;  4Q23 A;  1UBY A;  1ZW5 A;  2AZL A;  4F6X A;  2J1P A;  2ZCQ A;  1YQ7 A;  2I19 A;  5B0I A;  5ILK A;  4QPF A;  3ICZ A;  1N20 A;  4KQ5 A;  3QQV A;  4LLT A;  1FPS A;  3NRI A;  4RXA A;  3SDT A;  3PH7 A;  2PS8 A;  3KRO A;  3N5H F;  4LFV F;  5B00 A;  4KK2 A;  3ZOU A;  4H5C F;  4LFE A;  3WEI A;  4P0V A;  4KUX A;  3P41 A;  4RNQ A;  5DGM F;  2PS7 A;  5IL8 A;  3VJA A;  3VJ9 A;  3RYE A;  3NPR A;  3EFQ A;  5A0J A;  4FJQ A;  3RMG A;  1VG7 A;  5IK6 A;  1YHK A;  3AQB B;  3V1X A;  4KKM A;  5DZ2 A;  3SDR A;  2Q58 A;  3Q2Q A;  3V66 A;  3OAB B;  3ZCD A;  2Q9Y A;  3M0G A;  2AZJ A;  3N49 F;  3SDU A;  5ILD A;  4KQS A;  3ADZ A;  5H9D A;  4GAX A;  4NG6 A;  5JV0 F;  3WJK A;  4OKM A;  4NKE A;  5DGN F;  2Z4Z A;  3N3L F;  2ONG A;  5IMI A;  3M00 A;  3P8L A;  5ILH A;  3WEH A;  1PS1 A;  1V4H A;  4RXE A;  4KPJ A;  2E95 A;  2ZCR A;  2E8T A;  3LG5 A;  3OYR A;  5IKH A;  5AEL A;  3ACW A;  1HXA A;  2ZCS A;  4MC8 A;  4LFG A;  3ACX A;  2ZEV A;  3KRC A;  3PKO A;  5A0K A;  3CC9 A;  1N23 A;  3PDE A;  2OPM A;  1VG3 A;  4DEM F;  3B7L A;  4UMJ A;  2H8O A;  5A0I A;  2PS6 A;  1V4J A;  3UCA A;  1JFG A;  2OGD A;  4JXY A;  3WCM A;  4KPD A;  3WC9 A;  3G4D A;  3WSB A;  1RQJ A;  5HN8 A;  4KWD A;  4E1E A;  3AQC B;  4E9U A;  3RBM A;  3IBA A;  3OAC A;  4KVD A;  5IN8 A;  4E9Z A;  3RYW A;  3VJ8 A;  3KBK A;  3CKE A;  4LIX A;  2VF6 A;  2E92 A;  4FP4 A;  1KIY A;  1HM7 A;  2RAH A;  3MAV A;  4LXW A;  4KVW A;  5EAT A;  4NKF A;  3Q2Z A;  4LOB A;  3OAB A;  4PVY F;  5DJV F;  3WCC A;  3WEJ A;  2E94 A;  4DXJ A;  4H5E F;  4P0X A;  3WCH A;  4RXC A;  4PVX F;  4DZW A;  1YV5 A;  1HXC A;  3N45 F;  3M02 A;  4XQT F;  3ASX A;  1VG2 A;  4F62 A;  3N3D A;  3VJE A;  3OAC B;  2J5C A;  3P8R A;  5ERO A;  4OGU A;  3LLW A;  5IM1 A;  4OMH A;  1YYS A;  5JV2 F;  1WL3 A;  4KVI A;  4QXS F;  5JA0 F;  3N5J F;  4OKZ A;  2AET A;  2F89 F;  3DYH A;  3PYA A;  4N1Z F;  5IVG A;  3KRF B;  3W7F A;  2EWG A;  5IMP A;  1UBW A;  3AE0 A;  5C05 A;  3LMD A;  3QKC A;  2ONH A;  3TFP A;  2Z78 A;  4LPH F;  3TC1 A;  3VJC A;  1YHM A;  3Q30 A;  5AHU B;  3WJN A;  3ZL6 A;  1WL1 A;  2E93 A;  5DJP F;  3TS7 A;  5EAS A;  2J1O A;  4DWB A;  3KRP A;  4KQU A;  1YJ4 A;  3CP6 A;  5E8L A;  5IKA A;  4NFK F;  3VJD A;  3ZMB A;  2F8C F;  5ILZ A;  5E8H A;  3SDQ A;  5CG6 A;  4L2X F;  4XQR F;  4MC3 A; 
#chains in the Genus database with same CATH topology
 1V4E A;  3S9V A;  4WK5 A;  3M9U A;  2ZY1 A;  2AEK A;  2DH4 A;  5DIQ F;  1YYT A;  4LA6 A;  4GP2 A;  4DHD A;  2E8W A;  2Z4W A;  3M01 A;  3P5P A;  5DGS F;  3WCE A;  1VG6 A;  3LDW A;  3P5R A;  5B0K A;  2ZCO A;  1N1Z A;  5CG5 A;  4OMG A;  5B0L A;  4JVJ F;  3EZ3 A;  5DHI A;  3WCF A;  3KRP B;  3APZ A;  2AZK A;  4GP1 A;  1V4K A;  3G4F A;  2FOR A;  4GA3 A;  3SAE A;  3LOM A;  3VJB A;  2PS5 A;  4KVY A;  4NFJ F;  4NUA A;  3WCJ A;  3LVS A;  4JZB A;  5IL3 A;  3NF2 A;  4EA1 A;  5DJR F;  4N9U A;  3ID0 A;  1JFA A;  3WCD A;  2FTZ A;  3DYG A;  1HM4 A;  5DW7 A;  5AFX A;  3KRF A;  2Z7H A;  3Q1O A;  5JUZ F;  2Z50 A;  3BNX A;  3N6K F;  4LTZ A;  1WMW A;  3WEG A;  3ZMC A;  3N1V F;  4JXN A;  1N24 A;  1KIZ A;  3WCB A;  1RTR A;  2Q80 A;  4JZX A;  3KRA A;  1N1B A;  3LSN A;  2Z4Y A;  5IMN A;  2Z4V A;  3BNY A;  5B03 A;  4P0W A;  3N1W F;  3LZ9 A;  3N0G A;  1YYR A;  1YYU A;  5ERN A;  1YYQ A;  3WCI A;  3LGK A;  3WEK A;  5EAU A;  5B01 A;  1WL0 A;  3DYF A;  2PS4 A;  4LA5 A;  4LLS A;  2Q9Z A;  3V1V A;  1HX9 A;  2OA6 A;  3WCL A;  5HNA A;  4EA2 A;  3WCG A;  3TFV A;  3KB9 A;  2OPN A;  4EA0 A;  4LUU A;  3PYB A;  1RQI A;  3WCA A;  5AYP A;  3ICN A;  5HN9 A;  3KRA B;  4DI5 A;  3TFN A;  2Z4X A;  5HN7 A;  5E8K A;  1N21 A;  1EZF A;  4F6V A;  2O1O A;  4ZQ8 A;  3WEF A;  5I1U A;  1HXG A;  4LZ0 A;  3LGZ B;  2F8Z F;  1VG4 A;  4LZ3 A;  2F92 F;  3N46 F;  2E8X A;  3WE9 A;  5JV1 F;  5ILJ A;  3WSA A;  5ILI A;  3AQ0 A;  3KRO B;  4DWG A;  3LK5 A;  5IK9 A;  3SDV A;  5DHK A;  2Z52 A;  2ZEU A;  3ACY A;  4H5D F;  2F94 F;  1DI1 A;  1UBX A;  4JYX A;  4RXD A;  3ICK A;  1DGP A;  1YHL A;  2QIS A;  2E91 A;  1N22 A;  3EGT A;  4KFA A;  5B0M A;  3LEE A;  1WY0 A;  3NPK A;  3WJO A;  4NFI F;  3N0F A;  1UBV A;  5B02 A;  2F7M F;  5ERM A;  2Z7I A;  3ICM A;  3LJI A;  1V4I A;  2E4O A;  3S4J A;  5KSX F;  4RYP A;  2F9K F;  2E90 A;  2E8V A;  2E8U A;  3IPI A;  4HD1 A;  1WKZ A;  4K10 A;  4LPG F;  5IK0 A;  2P1C A;  3MZV A;  5ILY A;  1WL2 A;  4XQS F;  3KRC B;  4LTV A;  2AEL A;  4MC0 A;  5ER8 A;  4LZC A;  5B0J A;  4Q23 A;  1UBY A;  1ZW5 A;  2AZL A;  4F6X A;  2J1P A;  2ZCQ A;  1YQ7 A;  2I19 A;  5B0I A;  5ILK A;  4QPF A;  3ICZ A;  1N20 A;  4KQ5 A;  3QQV A;  4LLT A;  1FPS A;  3NRI A;  4RXA A;  3SDT A;  3PH7 A;  2PS8 A;  3KRO A;  3N5H F;  4LFV F;  5B00 A;  4KK2 A;  3ZOU A;  4H5C F;  4LFE A;  3WEI A;  4P0V A;  4KUX A;  3P41 A;  4RNQ A;  5DGM F;  2PS7 A;  5IL8 A;  3VJA A;  3VJ9 A;  3RYE A;  3NPR A;  3EFQ A;  5A0J A;  4FJQ A;  3RMG A;  1VG7 A;  5IK6 A;  1YHK A;  3AQB B;  3V1X A;  4KKM A;  5DZ2 A;  3SDR A;  2Q58 A;  3Q2Q A;  3V66 A;  3OAB B;  3ZCD A;  2Q9Y A;  3M0G A;  2AZJ A;  3N49 F;  3SDU A;  5ILD A;  4KQS A;  3ADZ A;  5H9D A;  4GAX A;  4NG6 A;  5JV0 F;  3WJK A;  4OKM A;  4NKE A;  5DGN F;  2Z4Z A;  3N3L F;  2ONG A;  5IMI A;  3M00 A;  3P8L A;  5ILH A;  3WEH A;  1PS1 A;  1V4H A;  4RXE A;  4KPJ A;  2E95 A;  2ZCR A;  2E8T A;  3LG5 A;  3OYR A;  5IKH A;  5AEL A;  3ACW A;  1HXA A;  2ZCS A;  4MC8 A;  4LFG A;  3ACX A;  2ZEV A;  3KRC A;  3PKO A;  5A0K A;  3CC9 A;  1N23 A;  3PDE A;  2OPM A;  1VG3 A;  4DEM F;  3B7L A;  4UMJ A;  2H8O A;  5A0I A;  2PS6 A;  1V4J A;  3UCA A;  1JFG A;  2OGD A;  4JXY A;  3WCM A;  4KPD A;  3WC9 A;  3G4D A;  3WSB A;  1RQJ A;  5HN8 A;  4KWD A;  4E1E A;  3AQC B;  4E9U A;  3RBM A;  3IBA A;  3OAC A;  4KVD A;  5IN8 A;  4E9Z A;  3RYW A;  3VJ8 A;  3KBK A;  3CKE A;  4LIX A;  2VF6 A;  2E92 A;  4FP4 A;  1KIY A;  1HM7 A;  2RAH A;  3MAV A;  4LXW A;  4KVW A;  5EAT A;  4NKF A;  3Q2Z A;  4LOB A;  3OAB A;  4PVY F;  5DJV F;  3WCC A;  3WEJ A;  2E94 A;  4DXJ A;  4H5E F;  4P0X A;  3WCH A;  4RXC A;  4PVX F;  4DZW A;  1YV5 A;  1HXC A;  3N45 F;  3M02 A;  4XQT F;  3ASX A;  1VG2 A;  4F62 A;  3N3D A;  3VJE A;  3OAC B;  2J5C A;  3P8R A;  5ERO A;  4OGU A;  3LLW A;  5IM1 A;  4OMH A;  1YYS A;  5JV2 F;  1WL3 A;  4KVI A;  4QXS F;  5JA0 F;  3N5J F;  4OKZ A;  2AET A;  2F89 F;  3DYH A;  3PYA A;  4N1Z F;  5IVG A;  3KRF B;  3W7F A;  2EWG A;  5IMP A;  1UBW A;  3AE0 A;  5C05 A;  3LMD A;  3QKC A;  2ONH A;  3TFP A;  2Z78 A;  4LPH F;  3TC1 A;  3VJC A;  1YHM A;  3Q30 A;  5AHU B;  3WJN A;  3ZL6 A;  1WL1 A;  2E93 A;  5DJP F;  3TS7 A;  5EAS A;  2J1O A;  4DWB A;  3KRP A;  4KQU A;  1YJ4 A;  3CP6 A;  5E8L A;  5IKA A;  4NFK F;  3VJD A;  3ZMB A;  2F8C F;  5ILZ A;  5E8H A;  3SDQ A;  5CG6 A;  4L2X F;  4XQR F;  4MC3 A; 
#chains in the Genus database with same CATH homology
 1V4E A;  3S9V A;  4WK5 A;  3M9U A;  2ZY1 A;  2AEK A;  2DH4 A;  5DIQ F;  1YYT A;  4LA6 A;  4GP2 A;  4DHD A;  2E8W A;  2Z4W A;  3M01 A;  3P5P A;  5DGS F;  3WCE A;  1VG6 A;  3LDW A;  3P5R A;  5B0K A;  2ZCO A;  1N1Z A;  5CG5 A;  4OMG A;  5B0L A;  4JVJ F;  3EZ3 A;  5DHI A;  3WCF A;  3KRP B;  3APZ A;  2AZK A;  4GP1 A;  1V4K A;  3G4F A;  2FOR A;  4GA3 A;  3SAE A;  3LOM A;  3VJB A;  2PS5 A;  4KVY A;  4NFJ F;  4NUA A;  3WCJ A;  3LVS A;  4JZB A;  5IL3 A;  3NF2 A;  4EA1 A;  5DJR F;  4N9U A;  3ID0 A;  1JFA A;  3WCD A;  2FTZ A;  3DYG A;  1HM4 A;  5DW7 A;  5AFX A;  3KRF A;  2Z7H A;  3Q1O A;  5JUZ F;  2Z50 A;  3BNX A;  3N6K F;  4LTZ A;  1WMW A;  3WEG A;  3ZMC A;  3N1V F;  4JXN A;  1N24 A;  1KIZ A;  3WCB A;  1RTR A;  2Q80 A;  4JZX A;  3KRA A;  1N1B A;  3LSN A;  2Z4Y A;  5IMN A;  2Z4V A;  3BNY A;  5B03 A;  4P0W A;  3N1W F;  3LZ9 A;  3N0G A;  1YYR A;  1YYU A;  5ERN A;  1YYQ A;  3WCI A;  3LGK A;  3WEK A;  5EAU A;  5B01 A;  1WL0 A;  3DYF A;  2PS4 A;  4LA5 A;  4LLS A;  2Q9Z A;  3V1V A;  1HX9 A;  2OA6 A;  3WCL A;  5HNA A;  4EA2 A;  3WCG A;  3TFV A;  3KB9 A;  2OPN A;  4EA0 A;  4LUU A;  3PYB A;  1RQI A;  3WCA A;  5AYP A;  3ICN A;  5HN9 A;  3KRA B;  4DI5 A;  3TFN A;  2Z4X A;  5HN7 A;  5E8K A;  1N21 A;  1EZF A;  4F6V A;  2O1O A;  4ZQ8 A;  3WEF A;  5I1U A;  1HXG A;  4LZ0 A;  3LGZ B;  2F8Z F;  1VG4 A;  4LZ3 A;  2F92 F;  3N46 F;  2E8X A;  3WE9 A;  5JV1 F;  5ILJ A;  3WSA A;  5ILI A;  3AQ0 A;  3KRO B;  4DWG A;  3LK5 A;  5IK9 A;  3SDV A;  5DHK A;  2Z52 A;  2ZEU A;  3ACY A;  4H5D F;  2F94 F;  1DI1 A;  1UBX A;  4JYX A;  4RXD A;  3ICK A;  1DGP A;  1YHL A;  2QIS A;  2E91 A;  1N22 A;  3EGT A;  4KFA A;  5B0M A;  3LEE A;  1WY0 A;  3NPK A;  3WJO A;  4NFI F;  3N0F A;  1UBV A;  5B02 A;  2F7M F;  5ERM A;  2Z7I A;  3ICM A;  3LJI A;  1V4I A;  2E4O A;  3S4J A;  5KSX F;  4RYP A;  2F9K F;  2E90 A;  2E8V A;  2E8U A;  3IPI A;  4HD1 A;  1WKZ A;  4K10 A;  4LPG F;  5IK0 A;  2P1C A;  3MZV A;  5ILY A;  1WL2 A;  4XQS F;  3KRC B;  4LTV A;  2AEL A;  4MC0 A;  5ER8 A;  4LZC A;  5B0J A;  4Q23 A;  1UBY A;  1ZW5 A;  2AZL A;  4F6X A;  2J1P A;  2ZCQ A;  1YQ7 A;  2I19 A;  5B0I A;  5ILK A;  4QPF A;  3ICZ A;  1N20 A;  4KQ5 A;  3QQV A;  4LLT A;  1FPS A;  3NRI A;  4RXA A;  3SDT A;  3PH7 A;  2PS8 A;  3KRO A;  3N5H F;  4LFV F;  5B00 A;  4KK2 A;  3ZOU A;  4H5C F;  4LFE A;  3WEI A;  4P0V A;  4KUX A;  3P41 A;  4RNQ A;  5DGM F;  2PS7 A;  5IL8 A;  3VJA A;  3VJ9 A;  3RYE A;  3NPR A;  3EFQ A;  5A0J A;  4FJQ A;  3RMG A;  1VG7 A;  5IK6 A;  1YHK A;  3AQB B;  3V1X A;  4KKM A;  5DZ2 A;  3SDR A;  2Q58 A;  3Q2Q A;  3V66 A;  3OAB B;  3ZCD A;  2Q9Y A;  3M0G A;  2AZJ A;  3N49 F;  3SDU A;  5ILD A;  4KQS A;  3ADZ A;  5H9D A;  4GAX A;  4NG6 A;  5JV0 F;  3WJK A;  4OKM A;  4NKE A;  5DGN F;  2Z4Z A;  3N3L F;  2ONG A;  5IMI A;  3M00 A;  3P8L A;  5ILH A;  3WEH A;  1PS1 A;  1V4H A;  4RXE A;  4KPJ A;  2E95 A;  2ZCR A;  2E8T A;  3LG5 A;  3OYR A;  5IKH A;  5AEL A;  3ACW A;  1HXA A;  2ZCS A;  4MC8 A;  4LFG A;  3ACX A;  2ZEV A;  3KRC A;  3PKO A;  5A0K A;  3CC9 A;  1N23 A;  3PDE A;  2OPM A;  1VG3 A;  4DEM F;  3B7L A;  4UMJ A;  2H8O A;  5A0I A;  2PS6 A;  1V4J A;  3UCA A;  1JFG A;  2OGD A;  4JXY A;  3WCM A;  4KPD A;  3WC9 A;  3G4D A;  3WSB A;  1RQJ A;  5HN8 A;  4KWD A;  4E1E A;  3AQC B;  4E9U A;  3RBM A;  3IBA A;  3OAC A;  4KVD A;  5IN8 A;  4E9Z A;  3RYW A;  3VJ8 A;  3KBK A;  3CKE A;  4LIX A;  2VF6 A;  2E92 A;  4FP4 A;  1KIY A;  1HM7 A;  2RAH A;  3MAV A;  4LXW A;  4KVW A;  5EAT A;  4NKF A;  3Q2Z A;  4LOB A;  3OAB A;  4PVY F;  5DJV F;  3WCC A;  3WEJ A;  2E94 A;  4DXJ A;  4H5E F;  4P0X A;  3WCH A;  4RXC A;  4PVX F;  4DZW A;  1YV5 A;  1HXC A;  3N45 F;  3M02 A;  4XQT F;  3ASX A;  1VG2 A;  4F62 A;  3N3D A;  3VJE A;  3OAC B;  2J5C A;  3P8R A;  5ERO A;  4OGU A;  3LLW A;  5IM1 A;  4OMH A;  1YYS A;  5JV2 F;  1WL3 A;  4KVI A;  4QXS F;  5JA0 F;  3N5J F;  4OKZ A;  2AET A;  2F89 F;  3DYH A;  3PYA A;  4N1Z F;  5IVG A;  3KRF B;  3W7F A;  2EWG A;  5IMP A;  1UBW A;  3AE0 A;  5C05 A;  3LMD A;  3QKC A;  2ONH A;  3TFP A;  2Z78 A;  4LPH F;  3TC1 A;  3VJC A;  1YHM A;  3Q30 A;  5AHU B;  3WJN A;  3ZL6 A;  1WL1 A;  2E93 A;  5DJP F;  3TS7 A;  5EAS A;  2J1O A;  4DWB A;  3KRP A;  4KQU A;  1YJ4 A;  3CP6 A;  5E8L A;  5IKA A;  4NFK F;  3VJD A;  3ZMB A;  2F8C F;  5ILZ A;  5E8H A;  3SDQ A;  5CG6 A;  4L2X F;  4XQR F;  4MC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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