3WC9A

The complex structure of hssqs wtih ligand, fspp
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
333
structure length
333
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 135
structure length 333
sequence length 333
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wc9A00
4DWGA 5DJVF 5E8KA 1HXGA 3QKCA 3WCBA 1N22A 5IK6A 3WEJA 3CKEA 5EASA 4NFIF 5JV2F 4DXJA 4DHDA 4NFJF 4P0XA 4Q23A 4KVDA 3LJIA 3ZMCA 3ASXA 4N1ZF 1VG6A 5IN8A 2E4OA 1HXCA 1N21A 5ILZA 1VG4A 4LPGF 2E8UA 1YYRA 4DEMF 3N5JF 3WSAA 2E8VA 3LGKA 5B0MA 5DGMF 1YYUA 3ACWA 3KRAA 3P8LA 1YYQA 3PYBA 4F6VA 2Q80A 1V4KA 2Z4XA 4EA0A 3KROA 2Q9YA 4KVWA 2DH4A 4LLSA 1YHLA 3WCDA 2E91A 4KVIA 5A0IA 2Z7HA 5E8LA 1V4HA 2O1OA 5DGNF 3RMGA 1N23A 1RQIA 4L2XF 3SDQA 3S4JA 4LTZA 5IMIA 2VF6A 2Q58A 1KIYA 4RXCA 1YYSA 1UBYA 5B00A 2E8XA 3B7LA 3QQVA 3P41A 4KKMA 3LK5A 3ADZA 3SDTA 3V1XA 4E9UA 4H5CF 1N20A 3PDEA 5B0LA 3LDWA 2PS7A 1V4JA 5DJPF 4RXDA 2I19A 3VJCA 4KQSA 5IM1A 5ILIA 4E9ZA 5IK0A 3WE9A 4RYPA 2ZCSA 3ACYA 2AZJA 3WCCA 2Z52A 1KIZA 2PS4A 3KRAB 4JYXA 4LPHF 3CC9A 4KQUA 4LXWA 3KROB 3WCIA 3KRCA 3EGTA 5HNAA 5JV1F 1JFGA 1DI1A 3WCLA 4UMJA 3ZL6A 3SDVA 3Q2QA 3Q30A 3N5HF 5EROA 2ZCRA 5JA0F 5IKAA 4GA3A 3WC9A 3NPRA 3BNXA 2F92F 5I1UA 3SAEA 4GAXA 5DJRF 5ERMA 4PVXF 2P1CA 5DHIA 5EATA 2OPNA 1WKZA 3TS7A 1UBWA 4RXAA 1ZW5A 5C05A 2F89F 4XQTF 3WCAA 3KRPB 3WJNA 5B01A 2E8WA 4JXNA 3VJAA 4K10A 2Q9ZA 2Z4YA 3M02A 3SDRA 3V1VA 3M9UA 3AE0A 1VG7A 3ZCDA 2E94A 4JZBA 1JFAA 1N1ZA 1RQJA 1RTRA 4E1EA 4P0WA 5HN8A 4KVYA 2FTZA 4EA1A 3WSBA 4LIXA 2Z78A 3WEIA 3N46F 2ZEUA 4LFVF 3ACXA 4KPDA 2E93A 1WMWA 5ILDA 4MC3A 3ZMBA 3RBMA 4KQ5A 1HXAA 1FPSA 2Z4WA 3AQBB 3P5PA 4OMGA 3KRCB 3N0GA 5DGSF 2ZCQA 4WK5A 2ONGA 1N24A 3DYHA 3G4FA 4QXSF 3KRFB 3Q2ZA 5DHKA 3N6KF 5ILYA 3N49F 3EZ3A 2PS8A 3LEEA 2E90A 5DZ2A 1VG3A 5ILHA 3KRPA 1YHKA 1V4EA 1YV5A 2F8CF 3VJ8A 4KK2A 2E8TA 3P5RA 3LOMA 4XQSF 3TFPA 2Z7IA 4OKZA 3CP6A 4LOBA 3N3DA 3PH7A 3M00A 4KPJA 1YHMA 3ID0A 4LZCA 2OA6A 3N3LF 3PYAA 5B0IA 3EFQA 1HM4A 3ICZA 2E95A 3DYFA 5AYPA 5DW7A 5IMPA 3DYGA 3LMDA 2AZKA 4DWBA 4EA2A 1YJ4A 3IBAA 4LZ0A 3LSNA 5AELA 4P0VA 3AQCB 3OABB 4KWDA 1YYTA 2Z4ZA 2AETA 3LGZB 2AEKA 3TFNA 5A0JA 1WL1A 2ZCOA 5IVGA 4LUUA 5KSXF 3KRFA 1VG2A 3LLWA 2PS6A 3W7FA 5IKHA 2ZY1A 2PS5A 2F8ZF 2J5CA 4F6XA 4OMHA 5JUZF 2AELA 1WL2A 4KUXA 3VJBA 5IK9A 3P8RA 3WEHA 2EWGA 1HX9A 3ICNA 2FORA 1WL0A 4JXYA 1WY0A 3WCFA 3WCJA 5IL8A 4DI5A 1V4IA 4NKEA 5ILKA 4RXEA 3SDUA 5DIQF 3MZVA 3KBKA 1UBVA 3OABA 3TC1A 3NRIA 3N45F 1WL3A 4LZ3A 5ER8A 5HN7A 1UBXA 1N1BA 4F62A 5H9DA 5JV0F 5CG5A 4JVJF 5E8HA 2OGDA 1DGPA 3APZA 2RAHA 3OACB 3KB9A 4LLTA 5B0JA 3N1WF 4DZWA 4RNQA 5AHUB 3ICMA 5HN9A 3RYEA 4ZQ8A 5ERNA 3Q1OA 3NF2A 4LTVA 3BNYA 4MC8A 2J1PA 5AFXA 5IL3A 4NFKF 3N1VF 3WEFA 4H5DF 5B02A 2OPMA 3WCEA 4HD1A 3LVSA 3VJDA 5IMNA 3WJOA 2E92A 3M0GA 5EAUA 3V66A 2F7MF 1HM7A 3UCAA 4KFAA 2AZLA 2Z4VA 4GP2A 3LG5A 4XQRF 4QPFA 3LZ9A 4H5EF 3G4DA 4JZXA 3WCHA 4FJQA 4MC0A 4GP1A 3TFVA 2F9KF 3RYWA 5B0KA 3IPIA 3WCGA 5ILJA 3N0FA 2QISA 3VJ9A 2ZEVA 3ICKA 4NKFA 1YQ7A 4OGUA 4LFEA 4PVYF 4OKMA 4LA5A 4FP4A 3VJEA 4LFGA 5B03A 3AQ0A 3OACA 3WJKA 2ONHA 3S9VA 4NG6A 3NPKA 1EZFA 2J1OA 3M01A 3OYRA 5A0KA 3PKOA 3WEGA 2Z50A 4LA6A 2H8OA 3MAVA 3WEKA 4N9UA 3WCMA 2F94F 1PS1A 3ZOUA 5CG6A 4NUAA
chains in the Genus database with same CATH superfamily
4DWGA 5DJVF 5E8KA 1HXGA 3QKCA 3WCBA 1N22A 5IK6A 3WEJA 3CKEA 5EASA 4NFIF 5JV2F 4DXJA 4DHDA 4NFJF 4P0XA 4Q23A 4KVDA 3LJIA 3ZMCA 3ASXA 4N1ZF 1VG6A 5IN8A 2E4OA 1HXCA 1N21A 5ILZA 1VG4A 4LPGF 2E8UA 1YYRA 4DEMF 3N5JF 3WSAA 2E8VA 3LGKA 5B0MA 5DGMF 1YYUA 3ACWA 3KRAA 3P8LA 1YYQA 3PYBA 4F6VA 2Q80A 1V4KA 2Z4XA 4EA0A 3KROA 2Q9YA 4KVWA 2DH4A 4LLSA 1YHLA 3WCDA 2E91A 4KVIA 5A0IA 2Z7HA 5E8LA 1V4HA 2O1OA 5DGNF 3RMGA 1N23A 1RQIA 4L2XF 3SDQA 3S4JA 4LTZA 5IMIA 2VF6A 2Q58A 1KIYA 4RXCA 1YYSA 1UBYA 5B00A 2E8XA 3B7LA 3QQVA 3P41A 4KKMA 3LK5A 3ADZA 3SDTA 3V1XA 4E9UA 4H5CF 1N20A 3PDEA 5B0LA 3LDWA 2PS7A 1V4JA 5DJPF 4RXDA 2I19A 3VJCA 4KQSA 5IM1A 5ILIA 4E9ZA 5IK0A 3WE9A 4RYPA 2ZCSA 3ACYA 2AZJA 3WCCA 2Z52A 1KIZA 2PS4A 3KRAB 4JYXA 4LPHF 3CC9A 4KQUA 4LXWA 3KROB 3WCIA 3KRCA 3EGTA 5HNAA 5JV1F 1JFGA 1DI1A 3WCLA 4UMJA 3ZL6A 3SDVA 3Q2QA 3Q30A 3N5HF 5EROA 2ZCRA 5JA0F 5IKAA 4GA3A 3WC9A 3NPRA 3BNXA 2F92F 5I1UA 3SAEA 4GAXA 5DJRF 5ERMA 4PVXF 2P1CA 5DHIA 5EATA 2OPNA 1WKZA 3TS7A 1UBWA 4RXAA 1ZW5A 5C05A 2F89F 4XQTF 3WCAA 3KRPB 3WJNA 5B01A 2E8WA 4JXNA 3VJAA 4K10A 2Q9ZA 2Z4YA 3M02A 3SDRA 3V1VA 3M9UA 3AE0A 1VG7A 3ZCDA 2E94A 4JZBA 1JFAA 1N1ZA 1RQJA 1RTRA 4E1EA 4P0WA 5HN8A 4KVYA 2FTZA 4EA1A 3WSBA 4LIXA 2Z78A 3WEIA 3N46F 2ZEUA 4LFVF 3ACXA 4KPDA 2E93A 1WMWA 5ILDA 4MC3A 3ZMBA 3RBMA 4KQ5A 1HXAA 1FPSA 2Z4WA 3AQBB 3P5PA 4OMGA 3KRCB 3N0GA 5DGSF 2ZCQA 4WK5A 2ONGA 1N24A 3DYHA 3G4FA 4QXSF 3KRFB 3Q2ZA 5DHKA 3N6KF 5ILYA 3N49F 3EZ3A 2PS8A 3LEEA 2E90A 5DZ2A 1VG3A 5ILHA 3KRPA 1YHKA 1V4EA 1YV5A 2F8CF 3VJ8A 4KK2A 2E8TA 3P5RA 3LOMA 4XQSF 3TFPA 2Z7IA 4OKZA 3CP6A 4LOBA 3N3DA 3PH7A 3M00A 4KPJA 1YHMA 3ID0A 4LZCA 2OA6A 3N3LF 3PYAA 5B0IA 3EFQA 1HM4A 3ICZA 2E95A 3DYFA 5AYPA 5DW7A 5IMPA 3DYGA 3LMDA 2AZKA 4DWBA 4EA2A 1YJ4A 3IBAA 4LZ0A 3LSNA 5AELA 4P0VA 3AQCB 3OABB 4KWDA 1YYTA 2Z4ZA 2AETA 3LGZB 2AEKA 3TFNA 5A0JA 1WL1A 2ZCOA 5IVGA 4LUUA 5KSXF 3KRFA 1VG2A 3LLWA 2PS6A 3W7FA 5IKHA 2ZY1A 2PS5A 2F8ZF 2J5CA 4F6XA 4OMHA 5JUZF 2AELA 1WL2A 4KUXA 3VJBA 5IK9A 3P8RA 3WEHA 2EWGA 1HX9A 3ICNA 2FORA 1WL0A 4JXYA 1WY0A 3WCFA 3WCJA 5IL8A 4DI5A 1V4IA 4NKEA 5ILKA 4RXEA 3SDUA 5DIQF 3MZVA 3KBKA 1UBVA 3OABA 3TC1A 3NRIA 3N45F 1WL3A 4LZ3A 5ER8A 5HN7A 1UBXA 1N1BA 4F62A 5H9DA 5JV0F 5CG5A 4JVJF 5E8HA 2OGDA 1DGPA 3APZA 2RAHA 3OACB 3KB9A 4LLTA 5B0JA 3N1WF 4DZWA 4RNQA 5AHUB 3ICMA 5HN9A 3RYEA 4ZQ8A 5ERNA 3Q1OA 3NF2A 4LTVA 3BNYA 4MC8A 2J1PA 5AFXA 5IL3A 4NFKF 3N1VF 3WEFA 4H5DF 5B02A 2OPMA 3WCEA 4HD1A 3LVSA 3VJDA 5IMNA 3WJOA 2E92A 3M0GA 5EAUA 3V66A 2F7MF 1HM7A 3UCAA 4KFAA 2AZLA 2Z4VA 4GP2A 3LG5A 4XQRF 4QPFA 3LZ9A 4H5EF 3G4DA 4JZXA 3WCHA 4FJQA 4MC0A 4GP1A 3TFVA 2F9KF 3RYWA 5B0KA 3IPIA 3WCGA 5ILJA 3N0FA 2QISA 3VJ9A 2ZEVA 3ICKA 4NKFA 1YQ7A 4OGUA 4LFEA 4PVYF 4OKMA 4LA5A 4FP4A 3VJEA 4LFGA 5B03A 3AQ0A 3OACA 3WJKA 2ONHA 3S9VA 4NG6A 3NPKA 1EZFA 2J1OA 3M01A 3OYRA 5A0KA 3PKOA 3WEGA 2Z50A 4LA6A 2H8OA 3MAVA 3WEKA 4N9UA 3WCMA 2F94F 1PS1A 3ZOUA 5CG6A 4NUAA
chains in the Genus database with same CATH topology
4DWGA 5DJVF 5E8KA 1HXGA 3QKCA 3WCBA 1N22A 5IK6A 3WEJA 3CKEA 5EASA 4NFIF 5JV2F 4DXJA 4DHDA 4NFJF 4P0XA 4Q23A 4KVDA 3LJIA 3ZMCA 3ASXA 4N1ZF 1VG6A 5IN8A 2E4OA 1HXCA 1N21A 5ILZA 1VG4A 4LPGF 2E8UA 1YYRA 4DEMF 3N5JF 3WSAA 2E8VA 3LGKA 5B0MA 5DGMF 1YYUA 3ACWA 3KRAA 3P8LA 1YYQA 3PYBA 4F6VA 2Q80A 1V4KA 2Z4XA 4EA0A 3KROA 2Q9YA 4KVWA 2DH4A 4LLSA 1YHLA 3WCDA 2E91A 4KVIA 5A0IA 2Z7HA 5E8LA 1V4HA 2O1OA 5DGNF 3RMGA 1N23A 1RQIA 4L2XF 3SDQA 3S4JA 4LTZA 5IMIA 2VF6A 2Q58A 1KIYA 4RXCA 1YYSA 1UBYA 5B00A 2E8XA 3B7LA 3QQVA 3P41A 4KKMA 3LK5A 3ADZA 3SDTA 3V1XA 4E9UA 4H5CF 1N20A 3PDEA 5B0LA 3LDWA 2PS7A 1V4JA 5DJPF 4RXDA 2I19A 3VJCA 4KQSA 5IM1A 5ILIA 4E9ZA 5IK0A 3WE9A 4RYPA 2ZCSA 3ACYA 2AZJA 3WCCA 2Z52A 1KIZA 2PS4A 3KRAB 4JYXA 4LPHF 3CC9A 4KQUA 4LXWA 3KROB 3WCIA 3KRCA 3EGTA 5HNAA 5JV1F 1JFGA 1DI1A 3WCLA 4UMJA 3ZL6A 3SDVA 3Q2QA 3Q30A 3N5HF 5EROA 2ZCRA 5JA0F 5IKAA 4GA3A 3WC9A 3NPRA 3BNXA 2F92F 5I1UA 3SAEA 4GAXA 5DJRF 5ERMA 4PVXF 2P1CA 5DHIA 5EATA 2OPNA 1WKZA 3TS7A 1UBWA 4RXAA 1ZW5A 5C05A 2F89F 4XQTF 3WCAA 3KRPB 3WJNA 5B01A 2E8WA 4JXNA 3VJAA 4K10A 2Q9ZA 2Z4YA 3M02A 3SDRA 3V1VA 3M9UA 3AE0A 1VG7A 3ZCDA 2E94A 4JZBA 1JFAA 1N1ZA 1RQJA 1RTRA 4E1EA 4P0WA 5HN8A 4KVYA 2FTZA 4EA1A 3WSBA 4LIXA 2Z78A 3WEIA 3N46F 2ZEUA 4LFVF 3ACXA 4KPDA 2E93A 1WMWA 5ILDA 4MC3A 3ZMBA 3RBMA 4KQ5A 1HXAA 1FPSA 2Z4WA 3AQBB 3P5PA 4OMGA 3KRCB 3N0GA 5DGSF 2ZCQA 4WK5A 2ONGA 1N24A 3DYHA 3G4FA 4QXSF 3KRFB 3Q2ZA 5DHKA 3N6KF 5ILYA 3N49F 3EZ3A 2PS8A 3LEEA 2E90A 5DZ2A 1VG3A 5ILHA 3KRPA 1YHKA 1V4EA 1YV5A 2F8CF 3VJ8A 4KK2A 2E8TA 3P5RA 3LOMA 4XQSF 3TFPA 2Z7IA 4OKZA 3CP6A 4LOBA 3N3DA 3PH7A 3M00A 4KPJA 1YHMA 3ID0A 4LZCA 2OA6A 3N3LF 3PYAA 5B0IA 3EFQA 1HM4A 3ICZA 2E95A 3DYFA 5AYPA 5DW7A 5IMPA 3DYGA 3LMDA 2AZKA 4DWBA 4EA2A 1YJ4A 3IBAA 4LZ0A 3LSNA 5AELA 4P0VA 3AQCB 3OABB 4KWDA 1YYTA 2Z4ZA 2AETA 3LGZB 2AEKA 3TFNA 5A0JA 1WL1A 2ZCOA 5IVGA 4LUUA 5KSXF 3KRFA 1VG2A 3LLWA 2PS6A 3W7FA 5IKHA 2ZY1A 2PS5A 2F8ZF 2J5CA 4F6XA 4OMHA 5JUZF 2AELA 1WL2A 4KUXA 3VJBA 5IK9A 3P8RA 3WEHA 2EWGA 1HX9A 3ICNA 2FORA 1WL0A 4JXYA 1WY0A 3WCFA 3WCJA 5IL8A 4DI5A 1V4IA 4NKEA 5ILKA 4RXEA 3SDUA 5DIQF 3MZVA 3KBKA 1UBVA 3OABA 3TC1A 3NRIA 3N45F 1WL3A 4LZ3A 5ER8A 5HN7A 1UBXA 1N1BA 4F62A 5H9DA 5JV0F 5CG5A 4JVJF 5E8HA 2OGDA 1DGPA 3APZA 2RAHA 3OACB 3KB9A 4LLTA 5B0JA 3N1WF 4DZWA 4RNQA 5AHUB 3ICMA 5HN9A 3RYEA 4ZQ8A 5ERNA 3Q1OA 3NF2A 4LTVA 3BNYA 4MC8A 2J1PA 5AFXA 5IL3A 4NFKF 3N1VF 3WEFA 4H5DF 5B02A 2OPMA 3WCEA 4HD1A 3LVSA 3VJDA 5IMNA 3WJOA 2E92A 3M0GA 5EAUA 3V66A 2F7MF 1HM7A 3UCAA 4KFAA 2AZLA 2Z4VA 4GP2A 3LG5A 4XQRF 4QPFA 3LZ9A 4H5EF 3G4DA 4JZXA 3WCHA 4FJQA 4MC0A 4GP1A 3TFVA 2F9KF 3RYWA 5B0KA 3IPIA 3WCGA 5ILJA 3N0FA 2QISA 3VJ9A 2ZEVA 3ICKA 4NKFA 1YQ7A 4OGUA 4LFEA 4PVYF 4OKMA 4LA5A 4FP4A 3VJEA 4LFGA 5B03A 3AQ0A 3OACA 3WJKA 2ONHA 3S9VA 4NG6A 3NPKA 1EZFA 2J1OA 3M01A 3OYRA 5A0KA 3PKOA 3WEGA 2Z50A 4LA6A 2H8OA 3MAVA 3WEKA 4N9UA 3WCMA 2F94F 1PS1A 3ZOUA 5CG6A 4NUAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DWG A;  5DJV F;  5E8K A;  1HXG A;  3QKC A;  3WCB A;  1N22 A;  5IK6 A;  3WEJ A;  3CKE A;  5EAS A;  4NFI F;  5JV2 F;  4DXJ A;  4DHD A;  4NFJ F;  4P0X A;  4Q23 A;  4KVD A;  3LJI A;  3ZMC A;  3ASX A;  4N1Z F;  1VG6 A;  5IN8 A;  2E4O A;  1HXC A;  1N21 A;  5ILZ A;  1VG4 A;  4LPG F;  2E8U A;  1YYR A;  4DEM F;  3N5J F;  3WSA A;  2E8V A;  3LGK A;  5B0M A;  5DGM F;  1YYU A;  3ACW A;  3KRA A;  3P8L A;  1YYQ A;  3PYB A;  4F6V A;  2Q80 A;  1V4K A;  2Z4X A;  4EA0 A;  3KRO A;  2Q9Y A;  4KVW A;  2DH4 A;  4LLS A;  1YHL A;  3WCD A;  2E91 A;  4KVI A;  5A0I A;  2Z7H A;  5E8L A;  1V4H A;  2O1O A;  5DGN F;  3RMG A;  1N23 A;  1RQI A;  4L2X F;  3SDQ A;  3S4J A;  4LTZ A;  5IMI A;  2VF6 A;  2Q58 A;  1KIY A;  4RXC A;  1YYS A;  1UBY A;  5B00 A;  2E8X A;  3B7L A;  3QQV A;  3P41 A;  4KKM A;  3LK5 A;  3ADZ A;  3SDT A;  3V1X A;  4E9U A;  4H5C F;  1N20 A;  3PDE A;  5B0L A;  3LDW A;  2PS7 A;  1V4J A;  5DJP F;  4RXD A;  2I19 A;  3VJC A;  4KQS A;  5IM1 A;  5ILI A;  4E9Z A;  5IK0 A;  3WE9 A;  4RYP A;  2ZCS A;  3ACY A;  2AZJ A;  3WCC A;  2Z52 A;  1KIZ A;  2PS4 A;  3KRA B;  4JYX A;  4LPH F;  3CC9 A;  4KQU A;  4LXW A;  3KRO B;  3WCI A;  3KRC A;  3EGT A;  5HNA A;  5JV1 F;  1JFG A;  1DI1 A;  3WCL A;  4UMJ A;  3ZL6 A;  3SDV A;  3Q2Q A;  3Q30 A;  3N5H F;  5ERO A;  2ZCR A;  5JA0 F;  5IKA A;  4GA3 A;  3WC9 A;  3NPR A;  3BNX A;  2F92 F;  5I1U A;  3SAE A;  4GAX A;  5DJR F;  5ERM A;  4PVX F;  2P1C A;  5DHI A;  5EAT A;  2OPN A;  1WKZ A;  3TS7 A;  1UBW A;  4RXA A;  1ZW5 A;  5C05 A;  2F89 F;  4XQT F;  3WCA A;  3KRP B;  3WJN A;  5B01 A;  2E8W A;  4JXN A;  3VJA A;  4K10 A;  2Q9Z A;  2Z4Y A;  3M02 A;  3SDR A;  3V1V A;  3M9U A;  3AE0 A;  1VG7 A;  3ZCD A;  2E94 A;  4JZB A;  1JFA A;  1N1Z A;  1RQJ A;  1RTR A;  4E1E A;  4P0W A;  5HN8 A;  4KVY A;  2FTZ A;  4EA1 A;  3WSB A;  4LIX A;  2Z78 A;  3WEI A;  3N46 F;  2ZEU A;  4LFV F;  3ACX A;  4KPD A;  2E93 A;  1WMW A;  5ILD A;  4MC3 A;  3ZMB A;  3RBM A;  4KQ5 A;  1HXA A;  1FPS A;  2Z4W A;  3AQB B;  3P5P A;  4OMG A;  3KRC B;  3N0G A;  5DGS F;  2ZCQ A;  4WK5 A;  2ONG A;  1N24 A;  3DYH A;  3G4F A;  4QXS F;  3KRF B;  3Q2Z A;  5DHK A;  3N6K F;  5ILY A;  3N49 F;  3EZ3 A;  2PS8 A;  3LEE A;  2E90 A;  5DZ2 A;  1VG3 A;  5ILH A;  3KRP A;  1YHK A;  1V4E A;  1YV5 A;  2F8C F;  3VJ8 A;  4KK2 A;  2E8T A;  3P5R A;  3LOM A;  4XQS F;  3TFP A;  2Z7I A;  4OKZ A;  3CP6 A;  4LOB A;  3N3D A;  3PH7 A;  3M00 A;  4KPJ A;  1YHM A;  3ID0 A;  4LZC A;  2OA6 A;  3N3L F;  3PYA A;  5B0I A;  3EFQ A;  1HM4 A;  3ICZ A;  2E95 A;  3DYF A;  5AYP A;  5DW7 A;  5IMP A;  3DYG A;  3LMD A;  2AZK A;  4DWB A;  4EA2 A;  1YJ4 A;  3IBA A;  4LZ0 A;  3LSN A;  5AEL A;  4P0V A;  3AQC B;  3OAB B;  4KWD A;  1YYT A;  2Z4Z A;  2AET A;  3LGZ B;  2AEK A;  3TFN A;  5A0J A;  1WL1 A;  2ZCO A;  5IVG A;  4LUU A;  5KSX F;  3KRF A;  1VG2 A;  3LLW A;  2PS6 A;  3W7F A;  5IKH A;  2ZY1 A;  2PS5 A;  2F8Z F;  2J5C A;  4F6X A;  4OMH A;  5JUZ F;  2AEL A;  1WL2 A;  4KUX A;  3VJB A;  5IK9 A;  3P8R A;  3WEH A;  2EWG A;  1HX9 A;  3ICN A;  2FOR A;  1WL0 A;  4JXY A;  1WY0 A;  3WCF A;  3WCJ A;  5IL8 A;  4DI5 A;  1V4I A;  4NKE A;  5ILK A;  4RXE A;  3SDU A;  5DIQ F;  3MZV A;  3KBK A;  1UBV A;  3OAB A;  3TC1 A;  3NRI A;  3N45 F;  1WL3 A;  4LZ3 A;  5ER8 A;  5HN7 A;  1UBX A;  1N1B A;  4F62 A;  5H9D A;  5JV0 F;  5CG5 A;  4JVJ F;  5E8H A;  2OGD A;  1DGP A;  3APZ A;  2RAH A;  3OAC B;  3KB9 A;  4LLT A;  5B0J A;  3N1W F;  4DZW A;  4RNQ A;  5AHU B;  3ICM A;  5HN9 A;  3RYE A;  4ZQ8 A;  5ERN A;  3Q1O A;  3NF2 A;  4LTV A;  3BNY A;  4MC8 A;  2J1P A;  5AFX A;  5IL3 A;  4NFK F;  3N1V F;  3WEF A;  4H5D F;  5B02 A;  2OPM A;  3WCE A;  4HD1 A;  3LVS A;  3VJD A;  5IMN A;  3WJO A;  2E92 A;  3M0G A;  5EAU A;  3V66 A;  2F7M F;  1HM7 A;  3UCA A;  4KFA A;  2AZL A;  2Z4V A;  4GP2 A;  3LG5 A;  4XQR F;  4QPF A;  3LZ9 A;  4H5E F;  3G4D A;  4JZX A;  3WCH A;  4FJQ A;  4MC0 A;  4GP1 A;  3TFV A;  2F9K F;  3RYW A;  5B0K A;  3IPI A;  3WCG A;  5ILJ A;  3N0F A;  2QIS A;  3VJ9 A;  2ZEV A;  3ICK A;  4NKF A;  1YQ7 A;  4OGU A;  4LFE A;  4PVY F;  4OKM A;  4LA5 A;  4FP4 A;  3VJE A;  4LFG A;  5B03 A;  3AQ0 A;  3OAC A;  3WJK A;  2ONH A;  3S9V A;  4NG6 A;  3NPK A;  1EZF A;  2J1O A;  3M01 A;  3OYR A;  5A0K A;  3PKO A;  3WEG A;  2Z50 A;  4LA6 A;  2H8O A;  3MAV A;  3WEK A;  4N9U A;  3WCM A;  2F94 F;  1PS1 A;  3ZOU A;  5CG6 A;  4NUA A; 
#chains in the Genus database with same CATH topology
 4DWG A;  5DJV F;  5E8K A;  1HXG A;  3QKC A;  3WCB A;  1N22 A;  5IK6 A;  3WEJ A;  3CKE A;  5EAS A;  4NFI F;  5JV2 F;  4DXJ A;  4DHD A;  4NFJ F;  4P0X A;  4Q23 A;  4KVD A;  3LJI A;  3ZMC A;  3ASX A;  4N1Z F;  1VG6 A;  5IN8 A;  2E4O A;  1HXC A;  1N21 A;  5ILZ A;  1VG4 A;  4LPG F;  2E8U A;  1YYR A;  4DEM F;  3N5J F;  3WSA A;  2E8V A;  3LGK A;  5B0M A;  5DGM F;  1YYU A;  3ACW A;  3KRA A;  3P8L A;  1YYQ A;  3PYB A;  4F6V A;  2Q80 A;  1V4K A;  2Z4X A;  4EA0 A;  3KRO A;  2Q9Y A;  4KVW A;  2DH4 A;  4LLS A;  1YHL A;  3WCD A;  2E91 A;  4KVI A;  5A0I A;  2Z7H A;  5E8L A;  1V4H A;  2O1O A;  5DGN F;  3RMG A;  1N23 A;  1RQI A;  4L2X F;  3SDQ A;  3S4J A;  4LTZ A;  5IMI A;  2VF6 A;  2Q58 A;  1KIY A;  4RXC A;  1YYS A;  1UBY A;  5B00 A;  2E8X A;  3B7L A;  3QQV A;  3P41 A;  4KKM A;  3LK5 A;  3ADZ A;  3SDT A;  3V1X A;  4E9U A;  4H5C F;  1N20 A;  3PDE A;  5B0L A;  3LDW A;  2PS7 A;  1V4J A;  5DJP F;  4RXD A;  2I19 A;  3VJC A;  4KQS A;  5IM1 A;  5ILI A;  4E9Z A;  5IK0 A;  3WE9 A;  4RYP A;  2ZCS A;  3ACY A;  2AZJ A;  3WCC A;  2Z52 A;  1KIZ A;  2PS4 A;  3KRA B;  4JYX A;  4LPH F;  3CC9 A;  4KQU A;  4LXW A;  3KRO B;  3WCI A;  3KRC A;  3EGT A;  5HNA A;  5JV1 F;  1JFG A;  1DI1 A;  3WCL A;  4UMJ A;  3ZL6 A;  3SDV A;  3Q2Q A;  3Q30 A;  3N5H F;  5ERO A;  2ZCR A;  5JA0 F;  5IKA A;  4GA3 A;  3WC9 A;  3NPR A;  3BNX A;  2F92 F;  5I1U A;  3SAE A;  4GAX A;  5DJR F;  5ERM A;  4PVX F;  2P1C A;  5DHI A;  5EAT A;  2OPN A;  1WKZ A;  3TS7 A;  1UBW A;  4RXA A;  1ZW5 A;  5C05 A;  2F89 F;  4XQT F;  3WCA A;  3KRP B;  3WJN A;  5B01 A;  2E8W A;  4JXN A;  3VJA A;  4K10 A;  2Q9Z A;  2Z4Y A;  3M02 A;  3SDR A;  3V1V A;  3M9U A;  3AE0 A;  1VG7 A;  3ZCD A;  2E94 A;  4JZB A;  1JFA A;  1N1Z A;  1RQJ A;  1RTR A;  4E1E A;  4P0W A;  5HN8 A;  4KVY A;  2FTZ A;  4EA1 A;  3WSB A;  4LIX A;  2Z78 A;  3WEI A;  3N46 F;  2ZEU A;  4LFV F;  3ACX A;  4KPD A;  2E93 A;  1WMW A;  5ILD A;  4MC3 A;  3ZMB A;  3RBM A;  4KQ5 A;  1HXA A;  1FPS A;  2Z4W A;  3AQB B;  3P5P A;  4OMG A;  3KRC B;  3N0G A;  5DGS F;  2ZCQ A;  4WK5 A;  2ONG A;  1N24 A;  3DYH A;  3G4F A;  4QXS F;  3KRF B;  3Q2Z A;  5DHK A;  3N6K F;  5ILY A;  3N49 F;  3EZ3 A;  2PS8 A;  3LEE A;  2E90 A;  5DZ2 A;  1VG3 A;  5ILH A;  3KRP A;  1YHK A;  1V4E A;  1YV5 A;  2F8C F;  3VJ8 A;  4KK2 A;  2E8T A;  3P5R A;  3LOM A;  4XQS F;  3TFP A;  2Z7I A;  4OKZ A;  3CP6 A;  4LOB A;  3N3D A;  3PH7 A;  3M00 A;  4KPJ A;  1YHM A;  3ID0 A;  4LZC A;  2OA6 A;  3N3L F;  3PYA A;  5B0I A;  3EFQ A;  1HM4 A;  3ICZ A;  2E95 A;  3DYF A;  5AYP A;  5DW7 A;  5IMP A;  3DYG A;  3LMD A;  2AZK A;  4DWB A;  4EA2 A;  1YJ4 A;  3IBA A;  4LZ0 A;  3LSN A;  5AEL A;  4P0V A;  3AQC B;  3OAB B;  4KWD A;  1YYT A;  2Z4Z A;  2AET A;  3LGZ B;  2AEK A;  3TFN A;  5A0J A;  1WL1 A;  2ZCO A;  5IVG A;  4LUU A;  5KSX F;  3KRF A;  1VG2 A;  3LLW A;  2PS6 A;  3W7F A;  5IKH A;  2ZY1 A;  2PS5 A;  2F8Z F;  2J5C A;  4F6X A;  4OMH A;  5JUZ F;  2AEL A;  1WL2 A;  4KUX A;  3VJB A;  5IK9 A;  3P8R A;  3WEH A;  2EWG A;  1HX9 A;  3ICN A;  2FOR A;  1WL0 A;  4JXY A;  1WY0 A;  3WCF A;  3WCJ A;  5IL8 A;  4DI5 A;  1V4I A;  4NKE A;  5ILK A;  4RXE A;  3SDU A;  5DIQ F;  3MZV A;  3KBK A;  1UBV A;  3OAB A;  3TC1 A;  3NRI A;  3N45 F;  1WL3 A;  4LZ3 A;  5ER8 A;  5HN7 A;  1UBX A;  1N1B A;  4F62 A;  5H9D A;  5JV0 F;  5CG5 A;  4JVJ F;  5E8H A;  2OGD A;  1DGP A;  3APZ A;  2RAH A;  3OAC B;  3KB9 A;  4LLT A;  5B0J A;  3N1W F;  4DZW A;  4RNQ A;  5AHU B;  3ICM A;  5HN9 A;  3RYE A;  4ZQ8 A;  5ERN A;  3Q1O A;  3NF2 A;  4LTV A;  3BNY A;  4MC8 A;  2J1P A;  5AFX A;  5IL3 A;  4NFK F;  3N1V F;  3WEF A;  4H5D F;  5B02 A;  2OPM A;  3WCE A;  4HD1 A;  3LVS A;  3VJD A;  5IMN A;  3WJO A;  2E92 A;  3M0G A;  5EAU A;  3V66 A;  2F7M F;  1HM7 A;  3UCA A;  4KFA A;  2AZL A;  2Z4V A;  4GP2 A;  3LG5 A;  4XQR F;  4QPF A;  3LZ9 A;  4H5E F;  3G4D A;  4JZX A;  3WCH A;  4FJQ A;  4MC0 A;  4GP1 A;  3TFV A;  2F9K F;  3RYW A;  5B0K A;  3IPI A;  3WCG A;  5ILJ A;  3N0F A;  2QIS A;  3VJ9 A;  2ZEV A;  3ICK A;  4NKF A;  1YQ7 A;  4OGU A;  4LFE A;  4PVY F;  4OKM A;  4LA5 A;  4FP4 A;  3VJE A;  4LFG A;  5B03 A;  3AQ0 A;  3OAC A;  3WJK A;  2ONH A;  3S9V A;  4NG6 A;  3NPK A;  1EZF A;  2J1O A;  3M01 A;  3OYR A;  5A0K A;  3PKO A;  3WEG A;  2Z50 A;  4LA6 A;  2H8O A;  3MAV A;  3WEK A;  4N9U A;  3WCM A;  2F94 F;  1PS1 A;  3ZOU A;  5CG6 A;  4NUA A; 
#chains in the Genus database with same CATH homology
 4DWG A;  5DJV F;  5E8K A;  1HXG A;  3QKC A;  3WCB A;  1N22 A;  5IK6 A;  3WEJ A;  3CKE A;  5EAS A;  4NFI F;  5JV2 F;  4DXJ A;  4DHD A;  4NFJ F;  4P0X A;  4Q23 A;  4KVD A;  3LJI A;  3ZMC A;  3ASX A;  4N1Z F;  1VG6 A;  5IN8 A;  2E4O A;  1HXC A;  1N21 A;  5ILZ A;  1VG4 A;  4LPG F;  2E8U A;  1YYR A;  4DEM F;  3N5J F;  3WSA A;  2E8V A;  3LGK A;  5B0M A;  5DGM F;  1YYU A;  3ACW A;  3KRA A;  3P8L A;  1YYQ A;  3PYB A;  4F6V A;  2Q80 A;  1V4K A;  2Z4X A;  4EA0 A;  3KRO A;  2Q9Y A;  4KVW A;  2DH4 A;  4LLS A;  1YHL A;  3WCD A;  2E91 A;  4KVI A;  5A0I A;  2Z7H A;  5E8L A;  1V4H A;  2O1O A;  5DGN F;  3RMG A;  1N23 A;  1RQI A;  4L2X F;  3SDQ A;  3S4J A;  4LTZ A;  5IMI A;  2VF6 A;  2Q58 A;  1KIY A;  4RXC A;  1YYS A;  1UBY A;  5B00 A;  2E8X A;  3B7L A;  3QQV A;  3P41 A;  4KKM A;  3LK5 A;  3ADZ A;  3SDT A;  3V1X A;  4E9U A;  4H5C F;  1N20 A;  3PDE A;  5B0L A;  3LDW A;  2PS7 A;  1V4J A;  5DJP F;  4RXD A;  2I19 A;  3VJC A;  4KQS A;  5IM1 A;  5ILI A;  4E9Z A;  5IK0 A;  3WE9 A;  4RYP A;  2ZCS A;  3ACY A;  2AZJ A;  3WCC A;  2Z52 A;  1KIZ A;  2PS4 A;  3KRA B;  4JYX A;  4LPH F;  3CC9 A;  4KQU A;  4LXW A;  3KRO B;  3WCI A;  3KRC A;  3EGT A;  5HNA A;  5JV1 F;  1JFG A;  1DI1 A;  3WCL A;  4UMJ A;  3ZL6 A;  3SDV A;  3Q2Q A;  3Q30 A;  3N5H F;  5ERO A;  2ZCR A;  5JA0 F;  5IKA A;  4GA3 A;  3WC9 A;  3NPR A;  3BNX A;  2F92 F;  5I1U A;  3SAE A;  4GAX A;  5DJR F;  5ERM A;  4PVX F;  2P1C A;  5DHI A;  5EAT A;  2OPN A;  1WKZ A;  3TS7 A;  1UBW A;  4RXA A;  1ZW5 A;  5C05 A;  2F89 F;  4XQT F;  3WCA A;  3KRP B;  3WJN A;  5B01 A;  2E8W A;  4JXN A;  3VJA A;  4K10 A;  2Q9Z A;  2Z4Y A;  3M02 A;  3SDR A;  3V1V A;  3M9U A;  3AE0 A;  1VG7 A;  3ZCD A;  2E94 A;  4JZB A;  1JFA A;  1N1Z A;  1RQJ A;  1RTR A;  4E1E A;  4P0W A;  5HN8 A;  4KVY A;  2FTZ A;  4EA1 A;  3WSB A;  4LIX A;  2Z78 A;  3WEI A;  3N46 F;  2ZEU A;  4LFV F;  3ACX A;  4KPD A;  2E93 A;  1WMW A;  5ILD A;  4MC3 A;  3ZMB A;  3RBM A;  4KQ5 A;  1HXA A;  1FPS A;  2Z4W A;  3AQB B;  3P5P A;  4OMG A;  3KRC B;  3N0G A;  5DGS F;  2ZCQ A;  4WK5 A;  2ONG A;  1N24 A;  3DYH A;  3G4F A;  4QXS F;  3KRF B;  3Q2Z A;  5DHK A;  3N6K F;  5ILY A;  3N49 F;  3EZ3 A;  2PS8 A;  3LEE A;  2E90 A;  5DZ2 A;  1VG3 A;  5ILH A;  3KRP A;  1YHK A;  1V4E A;  1YV5 A;  2F8C F;  3VJ8 A;  4KK2 A;  2E8T A;  3P5R A;  3LOM A;  4XQS F;  3TFP A;  2Z7I A;  4OKZ A;  3CP6 A;  4LOB A;  3N3D A;  3PH7 A;  3M00 A;  4KPJ A;  1YHM A;  3ID0 A;  4LZC A;  2OA6 A;  3N3L F;  3PYA A;  5B0I A;  3EFQ A;  1HM4 A;  3ICZ A;  2E95 A;  3DYF A;  5AYP A;  5DW7 A;  5IMP A;  3DYG A;  3LMD A;  2AZK A;  4DWB A;  4EA2 A;  1YJ4 A;  3IBA A;  4LZ0 A;  3LSN A;  5AEL A;  4P0V A;  3AQC B;  3OAB B;  4KWD A;  1YYT A;  2Z4Z A;  2AET A;  3LGZ B;  2AEK A;  3TFN A;  5A0J A;  1WL1 A;  2ZCO A;  5IVG A;  4LUU A;  5KSX F;  3KRF A;  1VG2 A;  3LLW A;  2PS6 A;  3W7F A;  5IKH A;  2ZY1 A;  2PS5 A;  2F8Z F;  2J5C A;  4F6X A;  4OMH A;  5JUZ F;  2AEL A;  1WL2 A;  4KUX A;  3VJB A;  5IK9 A;  3P8R A;  3WEH A;  2EWG A;  1HX9 A;  3ICN A;  2FOR A;  1WL0 A;  4JXY A;  1WY0 A;  3WCF A;  3WCJ A;  5IL8 A;  4DI5 A;  1V4I A;  4NKE A;  5ILK A;  4RXE A;  3SDU A;  5DIQ F;  3MZV A;  3KBK A;  1UBV A;  3OAB A;  3TC1 A;  3NRI A;  3N45 F;  1WL3 A;  4LZ3 A;  5ER8 A;  5HN7 A;  1UBX A;  1N1B A;  4F62 A;  5H9D A;  5JV0 F;  5CG5 A;  4JVJ F;  5E8H A;  2OGD A;  1DGP A;  3APZ A;  2RAH A;  3OAC B;  3KB9 A;  4LLT A;  5B0J A;  3N1W F;  4DZW A;  4RNQ A;  5AHU B;  3ICM A;  5HN9 A;  3RYE A;  4ZQ8 A;  5ERN A;  3Q1O A;  3NF2 A;  4LTV A;  3BNY A;  4MC8 A;  2J1P A;  5AFX A;  5IL3 A;  4NFK F;  3N1V F;  3WEF A;  4H5D F;  5B02 A;  2OPM A;  3WCE A;  4HD1 A;  3LVS A;  3VJD A;  5IMN A;  3WJO A;  2E92 A;  3M0G A;  5EAU A;  3V66 A;  2F7M F;  1HM7 A;  3UCA A;  4KFA A;  2AZL A;  2Z4V A;  4GP2 A;  3LG5 A;  4XQR F;  4QPF A;  3LZ9 A;  4H5E F;  3G4D A;  4JZX A;  3WCH A;  4FJQ A;  4MC0 A;  4GP1 A;  3TFV A;  2F9K F;  3RYW A;  5B0K A;  3IPI A;  3WCG A;  5ILJ A;  3N0F A;  2QIS A;  3VJ9 A;  2ZEV A;  3ICK A;  4NKF A;  1YQ7 A;  4OGU A;  4LFE A;  4PVY F;  4OKM A;  4LA5 A;  4FP4 A;  3VJE A;  4LFG A;  5B03 A;  3AQ0 A;  3OAC A;  3WJK A;  2ONH A;  3S9V A;  4NG6 A;  3NPK A;  1EZF A;  2J1O A;  3M01 A;  3OYR A;  5A0K A;  3PKO A;  3WEG A;  2Z50 A;  4LA6 A;  2H8O A;  3MAV A;  3WEK A;  4N9U A;  3WCM A;  2F94 F;  1PS1 A;  3ZOU A;  5CG6 A;  4NUA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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