3WEGA

Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate and magnesium ion
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Squalene synthase
publication title Structural insights into the catalytic mechanism of human squalene synthase
doi rcsb
source organism Homo sapiens
total genus 138
structure length 334
sequence length 334
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wegA00
3WEIA 1WL2A 2Z4XA 2J5CA 4KKMA 4LPGF 4Q23A 3V1VA 2OPMA 5IK0A 3WC9A 3N6KF 3APZA 3RBMA 1JFAA 4PVYF 4LLTA 3M9UA 4RXEA 3LGZB 3LEEA 3N0GA 5DGMF 5A0KA 1WKZA 2H8OA 2ONHA 4NFKF 5KSXF 2F8ZF 4E9ZA 2F7MF 5IN8A 3ICKA 2ZCQA 4KQUA 3VJCA 1UBVA 5JV2F 4LXWA 1N24A 3LZ9A 4P0XA 2Z50A 1V4EA 1HM7A 2OA6A 1N1BA 3KROB 4DWBA 4QXSF 5CG5A 2Z78A 4WK5A 1RQJA 4MC0A 4P0VA 3M00A 2Z4ZA 4P0WA 1YYTA 5I1UA 4GP2A 4F62A 3PH7A 3QKCA 3LMDA 5E8LA 2E8WA 5IMNA 3BNYA 1YV5A 3MAVA 3KRAA 1HM4A 4NFJF 3ZOUA 4DEMF 3PDEA 4KVIA 4LZCA 4LFGA 5A0IA 5ILDA 3OABB 5E8KA 4GA3A 2ZY1A 4KVYA 4N9UA 3VJAA 3ASXA 3WEGA 3WCJA 2AZLA 3N3DA 2E95A 5EAUA 3LLWA 4RXAA 4E9UA 5DJVF 3WCGA 1RTRA 4OMHA 1N1ZA 3KRPA 5ILJA 4UMJA 3WCCA 4RYPA 2VF6A 3SDUA 4JXNA 3ZL6A 2E8XA 3DYHA 3SDTA 4KFAA 2AZJA 3ZMBA 2Q9YA 3V1XA 3WJOA 3DYGA 1WMWA 5IKAA 5IM1A 1UBYA 2ZEUA 4LIXA 3MZVA 3KRPB 4KPDA 3CC9A 3NPKA 2ZEVA 1PS1A 3LVSA 5DJRF 3AQ0A 5JV1F 2Z4VA 3ACYA 5DGSF 5IK6A 5ILIA 3SAEA 3LGKA 3LJIA 5DW7A 4OKZA 5C05A 3ADZA 4ZQ8A 1JFGA 2I19A 4KQSA 3W7FA 3WEKA 2OPNA 5DHIA 3LK5A 4NG6A 4FP4A 5IL8A 5ER8A 4N1ZF 4XQTF 5B0JA 3NPRA 3P5PA 3SDQA 3ICNA 3EZ3A 4H5DF 3M02A 3OYRA 5ERNA 5ILKA 3RYEA 2AEKA 2ONGA 3KB9A 3SDVA 5ILHA 4OMGA 2F92F 1WL1A 5IK9A 2E94A 2AELA 3WCLA 1N23A 4NFIF 3DYFA 3WE9A 2E8VA 4EA2A 1KIYA 5AELA 4LZ0A 5B0LA 2ZCOA 2P1CA 3RMGA 4NUAA 5ERMA 1WY0A 3TC1A 5EROA 2J1PA 1HXGA 4F6VA 3AE0A 4LZ3A 3WCDA 3OACA 4H5EF 3KRFA 4GP1A 5ILYA 1UBXA 4JYXA 3WCAA 3EFQA 3WCBA 3LG5A 1YQ7A 4NKEA 4RXCA 3ACWA 3WSAA 1DGPA 4K10A 4LUUA 5DIQF 3N3LF 3WCFA 2FORA 5AFXA 3TFPA 3WEFA 1ZW5A 3TFVA 2Z7HA 3VJ8A 3LDWA 2RAHA 5AHUB 3CKEA 4EA1A 5HNAA 3ZMCA 1YHLA 4LPHF 5JV0F 4JXYA 1WL0A 2E93A 3KRAB 5CG6A 1V4IA 1VG7A 3PYAA 5HN7A 3ID0A 1VG3A 2F89F 1N22A 5B0MA 3N49F 2Q9ZA 2E4OA 3IBAA 3ACXA 1N21A 3VJBA 2PS5A 4LA5A 3WEHA 4KPJA 3V66A 1DI1A 5DGNF 3ZCDA 2OGDA 3Q30A 3N1WF 2AETA 3WCEA 2O1OA 2PS4A 3G4DA 3Q2QA 4RNQA 5DJPF 3WCIA 3PKOA 3N1VF 4GAXA 5H9DA 5B0KA 2Q58A 3N45F 1RQIA 4NKFA 2ZCSA 5EASA 2Z4YA 3AQBB 1KIZA 2E90A 4LFEA 4DI5A 4DHDA 1YHMA 1N20A 3QQVA 3BNXA 4LOBA 3WCHA 3N5JF 5JUZF 2F94F 3LOMA 3P8LA 3VJEA 2DH4A 3SDRA 3Q2ZA 3P8RA 1WL3A 4F6XA 3NRIA 4JZBA 3PYBA 3ICZA 3RYWA 3KROA 1HX9A 2E8TA 1YYQA 4KVDA 2QISA 3ICMA 3KBKA 5DHKA 2PS7A 2J1OA 3Q1OA 3NF2A 4LTZA 1YHKA 3N0FA 3KRCA 3VJ9A 2Z52A 1V4KA 5IMPA 5ILZA 1YYUA 3N5HF 4KK2A 1EZFA 2ZCRA 5HN8A 2Z7IA 5B0IA 4XQSF 4OKMA 1YJ4A 3P5RA 3EGTA 4JZXA 3WSBA 3OABA 4KUXA 5IKHA 4KVWA 1FPSA 1HXAA 5AYPA 3WJKA 5B01A 3KRCB 3OACB 3AQCB 4H5CF 2Z4WA 3WJNA 4LFVF 3KRFB 3CP6A 1V4HA 1YYRA 3S4JA 1VG6A 3P41A 3LSNA 2Q80A 4RXDA 2E91A 3WCMA 5DZ2A 4DWGA 3TFNA 4QPFA 3WEJA 4L2XF 5EATA 4FJQA 2AZKA 4LLSA 4MC3A 3B7LA 2F9KF 5IVGA 3G4FA 2FTZA 5B02A 2PS8A 4DZWA 4E1EA 3S9VA 3TS7A 1HXCA 1UBWA 3M01A 2E92A 1VG2A 2PS6A 3IPIA 5E8HA 2EWGA 2E8UA 4JVJF 4EA0A 3N46F 4HD1A 4LA6A 3M0GA 4XQRF 2F8CF 4KWDA 5A0JA 4LTVA 1YYSA 5HN9A 5IL3A 5B03A 4MC8A 4DXJA 4OGUA 5JA0F 4KQ5A 1V4JA 1VG4A 4PVXF 5B00A 3VJDA 3UCAA 5IMIA
chains in the Genus database with same CATH superfamily
3WEIA 1WL2A 2Z4XA 2J5CA 4KKMA 4LPGF 4Q23A 3V1VA 2OPMA 5IK0A 3WC9A 3N6KF 3APZA 3RBMA 1JFAA 4PVYF 4LLTA 3M9UA 4RXEA 3LGZB 3LEEA 3N0GA 5DGMF 5A0KA 1WKZA 2H8OA 2ONHA 4NFKF 5KSXF 2F8ZF 4E9ZA 2F7MF 5IN8A 3ICKA 2ZCQA 4KQUA 3VJCA 1UBVA 5JV2F 4LXWA 1N24A 3LZ9A 4P0XA 2Z50A 1V4EA 1HM7A 2OA6A 1N1BA 3KROB 4DWBA 4QXSF 5CG5A 2Z78A 4WK5A 1RQJA 4MC0A 4P0VA 3M00A 2Z4ZA 4P0WA 1YYTA 5I1UA 4GP2A 4F62A 3PH7A 3QKCA 3LMDA 5E8LA 2E8WA 5IMNA 3BNYA 1YV5A 3MAVA 3KRAA 1HM4A 4NFJF 3ZOUA 4DEMF 3PDEA 4KVIA 4LZCA 4LFGA 5A0IA 5ILDA 3OABB 5E8KA 4GA3A 2ZY1A 4KVYA 4N9UA 3VJAA 3ASXA 3WEGA 3WCJA 2AZLA 3N3DA 2E95A 5EAUA 3LLWA 4RXAA 4E9UA 5DJVF 3WCGA 1RTRA 4OMHA 1N1ZA 3KRPA 5ILJA 4UMJA 3WCCA 4RYPA 2VF6A 3SDUA 4JXNA 3ZL6A 2E8XA 3DYHA 3SDTA 4KFAA 2AZJA 3ZMBA 2Q9YA 3V1XA 3WJOA 3DYGA 1WMWA 5IKAA 5IM1A 1UBYA 2ZEUA 4LIXA 3MZVA 3KRPB 4KPDA 3CC9A 3NPKA 2ZEVA 1PS1A 3LVSA 5DJRF 3AQ0A 5JV1F 2Z4VA 3ACYA 5DGSF 5IK6A 5ILIA 3SAEA 3LGKA 3LJIA 5DW7A 4OKZA 5C05A 3ADZA 4ZQ8A 1JFGA 2I19A 4KQSA 3W7FA 3WEKA 2OPNA 5DHIA 3LK5A 4NG6A 4FP4A 5IL8A 5ER8A 4N1ZF 4XQTF 5B0JA 3NPRA 3P5PA 3SDQA 3ICNA 3EZ3A 4H5DF 3M02A 3OYRA 5ERNA 5ILKA 3RYEA 2AEKA 2ONGA 3KB9A 3SDVA 5ILHA 4OMGA 2F92F 1WL1A 5IK9A 2E94A 2AELA 3WCLA 1N23A 4NFIF 3DYFA 3WE9A 2E8VA 4EA2A 1KIYA 5AELA 4LZ0A 5B0LA 2ZCOA 2P1CA 3RMGA 4NUAA 5ERMA 1WY0A 3TC1A 5EROA 2J1PA 1HXGA 4F6VA 3AE0A 4LZ3A 3WCDA 3OACA 4H5EF 3KRFA 4GP1A 5ILYA 1UBXA 4JYXA 3WCAA 3EFQA 3WCBA 3LG5A 1YQ7A 4NKEA 4RXCA 3ACWA 3WSAA 1DGPA 4K10A 4LUUA 5DIQF 3N3LF 3WCFA 2FORA 5AFXA 3TFPA 3WEFA 1ZW5A 3TFVA 2Z7HA 3VJ8A 3LDWA 2RAHA 5AHUB 3CKEA 4EA1A 5HNAA 3ZMCA 1YHLA 4LPHF 5JV0F 4JXYA 1WL0A 2E93A 3KRAB 5CG6A 1V4IA 1VG7A 3PYAA 5HN7A 3ID0A 1VG3A 2F89F 1N22A 5B0MA 3N49F 2Q9ZA 2E4OA 3IBAA 3ACXA 1N21A 3VJBA 2PS5A 4LA5A 3WEHA 4KPJA 3V66A 1DI1A 5DGNF 3ZCDA 2OGDA 3Q30A 3N1WF 2AETA 3WCEA 2O1OA 2PS4A 3G4DA 3Q2QA 4RNQA 5DJPF 3WCIA 3PKOA 3N1VF 4GAXA 5H9DA 5B0KA 2Q58A 3N45F 1RQIA 4NKFA 2ZCSA 5EASA 2Z4YA 3AQBB 1KIZA 2E90A 4LFEA 4DI5A 4DHDA 1YHMA 1N20A 3QQVA 3BNXA 4LOBA 3WCHA 3N5JF 5JUZF 2F94F 3LOMA 3P8LA 3VJEA 2DH4A 3SDRA 3Q2ZA 3P8RA 1WL3A 4F6XA 3NRIA 4JZBA 3PYBA 3ICZA 3RYWA 3KROA 1HX9A 2E8TA 1YYQA 4KVDA 2QISA 3ICMA 3KBKA 5DHKA 2PS7A 2J1OA 3Q1OA 3NF2A 4LTZA 1YHKA 3N0FA 3KRCA 3VJ9A 2Z52A 1V4KA 5IMPA 5ILZA 1YYUA 3N5HF 4KK2A 1EZFA 2ZCRA 5HN8A 2Z7IA 5B0IA 4XQSF 4OKMA 1YJ4A 3P5RA 3EGTA 4JZXA 3WSBA 3OABA 4KUXA 5IKHA 4KVWA 1FPSA 1HXAA 5AYPA 3WJKA 5B01A 3KRCB 3OACB 3AQCB 4H5CF 2Z4WA 3WJNA 4LFVF 3KRFB 3CP6A 1V4HA 1YYRA 3S4JA 1VG6A 3P41A 3LSNA 2Q80A 4RXDA 2E91A 3WCMA 5DZ2A 4DWGA 3TFNA 4QPFA 3WEJA 4L2XF 5EATA 4FJQA 2AZKA 4LLSA 4MC3A 3B7LA 2F9KF 5IVGA 3G4FA 2FTZA 5B02A 2PS8A 4DZWA 4E1EA 3S9VA 3TS7A 1HXCA 1UBWA 3M01A 2E92A 1VG2A 2PS6A 3IPIA 5E8HA 2EWGA 2E8UA 4JVJF 4EA0A 3N46F 4HD1A 4LA6A 3M0GA 4XQRF 2F8CF 4KWDA 5A0JA 4LTVA 1YYSA 5HN9A 5IL3A 5B03A 4MC8A 4DXJA 4OGUA 5JA0F 4KQ5A 1V4JA 1VG4A 4PVXF 5B00A 3VJDA 3UCAA 5IMIA
chains in the Genus database with same CATH topology
3WEIA 1WL2A 2Z4XA 2J5CA 4KKMA 4LPGF 4Q23A 3V1VA 2OPMA 5IK0A 3WC9A 3N6KF 3APZA 3RBMA 1JFAA 4PVYF 4LLTA 3M9UA 4RXEA 3LGZB 3LEEA 3N0GA 5DGMF 5A0KA 1WKZA 2H8OA 2ONHA 4NFKF 5KSXF 2F8ZF 4E9ZA 2F7MF 5IN8A 3ICKA 2ZCQA 4KQUA 3VJCA 1UBVA 5JV2F 4LXWA 1N24A 3LZ9A 4P0XA 2Z50A 1V4EA 1HM7A 2OA6A 1N1BA 3KROB 4DWBA 4QXSF 5CG5A 2Z78A 4WK5A 1RQJA 4MC0A 4P0VA 3M00A 2Z4ZA 4P0WA 1YYTA 5I1UA 4GP2A 4F62A 3PH7A 3QKCA 3LMDA 5E8LA 2E8WA 5IMNA 3BNYA 1YV5A 3MAVA 3KRAA 1HM4A 4NFJF 3ZOUA 4DEMF 3PDEA 4KVIA 4LZCA 4LFGA 5A0IA 5ILDA 3OABB 5E8KA 4GA3A 2ZY1A 4KVYA 4N9UA 3VJAA 3ASXA 3WEGA 3WCJA 2AZLA 3N3DA 2E95A 5EAUA 3LLWA 4RXAA 4E9UA 5DJVF 3WCGA 1RTRA 4OMHA 1N1ZA 3KRPA 5ILJA 4UMJA 3WCCA 4RYPA 2VF6A 3SDUA 4JXNA 3ZL6A 2E8XA 3DYHA 3SDTA 4KFAA 2AZJA 3ZMBA 2Q9YA 3V1XA 3WJOA 3DYGA 1WMWA 5IKAA 5IM1A 1UBYA 2ZEUA 4LIXA 3MZVA 3KRPB 4KPDA 3CC9A 3NPKA 2ZEVA 1PS1A 3LVSA 5DJRF 3AQ0A 5JV1F 2Z4VA 3ACYA 5DGSF 5IK6A 5ILIA 3SAEA 3LGKA 3LJIA 5DW7A 4OKZA 5C05A 3ADZA 4ZQ8A 1JFGA 2I19A 4KQSA 3W7FA 3WEKA 2OPNA 5DHIA 3LK5A 4NG6A 4FP4A 5IL8A 5ER8A 4N1ZF 4XQTF 5B0JA 3NPRA 3P5PA 3SDQA 3ICNA 3EZ3A 4H5DF 3M02A 3OYRA 5ERNA 5ILKA 3RYEA 2AEKA 2ONGA 3KB9A 3SDVA 5ILHA 4OMGA 2F92F 1WL1A 5IK9A 2E94A 2AELA 3WCLA 1N23A 4NFIF 3DYFA 3WE9A 2E8VA 4EA2A 1KIYA 5AELA 4LZ0A 5B0LA 2ZCOA 2P1CA 3RMGA 4NUAA 5ERMA 1WY0A 3TC1A 5EROA 2J1PA 1HXGA 4F6VA 3AE0A 4LZ3A 3WCDA 3OACA 4H5EF 3KRFA 4GP1A 5ILYA 1UBXA 4JYXA 3WCAA 3EFQA 3WCBA 3LG5A 1YQ7A 4NKEA 4RXCA 3ACWA 3WSAA 1DGPA 4K10A 4LUUA 5DIQF 3N3LF 3WCFA 2FORA 5AFXA 3TFPA 3WEFA 1ZW5A 3TFVA 2Z7HA 3VJ8A 3LDWA 2RAHA 5AHUB 3CKEA 4EA1A 5HNAA 3ZMCA 1YHLA 4LPHF 5JV0F 4JXYA 1WL0A 2E93A 3KRAB 5CG6A 1V4IA 1VG7A 3PYAA 5HN7A 3ID0A 1VG3A 2F89F 1N22A 5B0MA 3N49F 2Q9ZA 2E4OA 3IBAA 3ACXA 1N21A 3VJBA 2PS5A 4LA5A 3WEHA 4KPJA 3V66A 1DI1A 5DGNF 3ZCDA 2OGDA 3Q30A 3N1WF 2AETA 3WCEA 2O1OA 2PS4A 3G4DA 3Q2QA 4RNQA 5DJPF 3WCIA 3PKOA 3N1VF 4GAXA 5H9DA 5B0KA 2Q58A 3N45F 1RQIA 4NKFA 2ZCSA 5EASA 2Z4YA 3AQBB 1KIZA 2E90A 4LFEA 4DI5A 4DHDA 1YHMA 1N20A 3QQVA 3BNXA 4LOBA 3WCHA 3N5JF 5JUZF 2F94F 3LOMA 3P8LA 3VJEA 2DH4A 3SDRA 3Q2ZA 3P8RA 1WL3A 4F6XA 3NRIA 4JZBA 3PYBA 3ICZA 3RYWA 3KROA 1HX9A 2E8TA 1YYQA 4KVDA 2QISA 3ICMA 3KBKA 5DHKA 2PS7A 2J1OA 3Q1OA 3NF2A 4LTZA 1YHKA 3N0FA 3KRCA 3VJ9A 2Z52A 1V4KA 5IMPA 5ILZA 1YYUA 3N5HF 4KK2A 1EZFA 2ZCRA 5HN8A 2Z7IA 5B0IA 4XQSF 4OKMA 1YJ4A 3P5RA 3EGTA 4JZXA 3WSBA 3OABA 4KUXA 5IKHA 4KVWA 1FPSA 1HXAA 5AYPA 3WJKA 5B01A 3KRCB 3OACB 3AQCB 4H5CF 2Z4WA 3WJNA 4LFVF 3KRFB 3CP6A 1V4HA 1YYRA 3S4JA 1VG6A 3P41A 3LSNA 2Q80A 4RXDA 2E91A 3WCMA 5DZ2A 4DWGA 3TFNA 4QPFA 3WEJA 4L2XF 5EATA 4FJQA 2AZKA 4LLSA 4MC3A 3B7LA 2F9KF 5IVGA 3G4FA 2FTZA 5B02A 2PS8A 4DZWA 4E1EA 3S9VA 3TS7A 1HXCA 1UBWA 3M01A 2E92A 1VG2A 2PS6A 3IPIA 5E8HA 2EWGA 2E8UA 4JVJF 4EA0A 3N46F 4HD1A 4LA6A 3M0GA 4XQRF 2F8CF 4KWDA 5A0JA 4LTVA 1YYSA 5HN9A 5IL3A 5B03A 4MC8A 4DXJA 4OGUA 5JA0F 4KQ5A 1V4JA 1VG4A 4PVXF 5B00A 3VJDA 3UCAA 5IMIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WEI A;  1WL2 A;  2Z4X A;  2J5C A;  4KKM A;  4LPG F;  4Q23 A;  3V1V A;  2OPM A;  5IK0 A;  3WC9 A;  3N6K F;  3APZ A;  3RBM A;  1JFA A;  4PVY F;  4LLT A;  3M9U A;  4RXE A;  3LGZ B;  3LEE A;  3N0G A;  5DGM F;  5A0K A;  1WKZ A;  2H8O A;  2ONH A;  4NFK F;  5KSX F;  2F8Z F;  4E9Z A;  2F7M F;  5IN8 A;  3ICK A;  2ZCQ A;  4KQU A;  3VJC A;  1UBV A;  5JV2 F;  4LXW A;  1N24 A;  3LZ9 A;  4P0X A;  2Z50 A;  1V4E A;  1HM7 A;  2OA6 A;  1N1B A;  3KRO B;  4DWB A;  4QXS F;  5CG5 A;  2Z78 A;  4WK5 A;  1RQJ A;  4MC0 A;  4P0V A;  3M00 A;  2Z4Z A;  4P0W A;  1YYT A;  5I1U A;  4GP2 A;  4F62 A;  3PH7 A;  3QKC A;  3LMD A;  5E8L A;  2E8W A;  5IMN A;  3BNY A;  1YV5 A;  3MAV A;  3KRA A;  1HM4 A;  4NFJ F;  3ZOU A;  4DEM F;  3PDE A;  4KVI A;  4LZC A;  4LFG A;  5A0I A;  5ILD A;  3OAB B;  5E8K A;  4GA3 A;  2ZY1 A;  4KVY A;  4N9U A;  3VJA A;  3ASX A;  3WEG A;  3WCJ A;  2AZL A;  3N3D A;  2E95 A;  5EAU A;  3LLW A;  4RXA A;  4E9U A;  5DJV F;  3WCG A;  1RTR A;  4OMH A;  1N1Z A;  3KRP A;  5ILJ A;  4UMJ A;  3WCC A;  4RYP A;  2VF6 A;  3SDU A;  4JXN A;  3ZL6 A;  2E8X A;  3DYH A;  3SDT A;  4KFA A;  2AZJ A;  3ZMB A;  2Q9Y A;  3V1X A;  3WJO A;  3DYG A;  1WMW A;  5IKA A;  5IM1 A;  1UBY A;  2ZEU A;  4LIX A;  3MZV A;  3KRP B;  4KPD A;  3CC9 A;  3NPK A;  2ZEV A;  1PS1 A;  3LVS A;  5DJR F;  3AQ0 A;  5JV1 F;  2Z4V A;  3ACY A;  5DGS F;  5IK6 A;  5ILI A;  3SAE A;  3LGK A;  3LJI A;  5DW7 A;  4OKZ A;  5C05 A;  3ADZ A;  4ZQ8 A;  1JFG A;  2I19 A;  4KQS A;  3W7F A;  3WEK A;  2OPN A;  5DHI A;  3LK5 A;  4NG6 A;  4FP4 A;  5IL8 A;  5ER8 A;  4N1Z F;  4XQT F;  5B0J A;  3NPR A;  3P5P A;  3SDQ A;  3ICN A;  3EZ3 A;  4H5D F;  3M02 A;  3OYR A;  5ERN A;  5ILK A;  3RYE A;  2AEK A;  2ONG A;  3KB9 A;  3SDV A;  5ILH A;  4OMG A;  2F92 F;  1WL1 A;  5IK9 A;  2E94 A;  2AEL A;  3WCL A;  1N23 A;  4NFI F;  3DYF A;  3WE9 A;  2E8V A;  4EA2 A;  1KIY A;  5AEL A;  4LZ0 A;  5B0L A;  2ZCO A;  2P1C A;  3RMG A;  4NUA A;  5ERM A;  1WY0 A;  3TC1 A;  5ERO A;  2J1P A;  1HXG A;  4F6V A;  3AE0 A;  4LZ3 A;  3WCD A;  3OAC A;  4H5E F;  3KRF A;  4GP1 A;  5ILY A;  1UBX A;  4JYX A;  3WCA A;  3EFQ A;  3WCB A;  3LG5 A;  1YQ7 A;  4NKE A;  4RXC A;  3ACW A;  3WSA A;  1DGP A;  4K10 A;  4LUU A;  5DIQ F;  3N3L F;  3WCF A;  2FOR A;  5AFX A;  3TFP A;  3WEF A;  1ZW5 A;  3TFV A;  2Z7H A;  3VJ8 A;  3LDW A;  2RAH A;  5AHU B;  3CKE A;  4EA1 A;  5HNA A;  3ZMC A;  1YHL A;  4LPH F;  5JV0 F;  4JXY A;  1WL0 A;  2E93 A;  3KRA B;  5CG6 A;  1V4I A;  1VG7 A;  3PYA A;  5HN7 A;  3ID0 A;  1VG3 A;  2F89 F;  1N22 A;  5B0M A;  3N49 F;  2Q9Z A;  2E4O A;  3IBA A;  3ACX A;  1N21 A;  3VJB A;  2PS5 A;  4LA5 A;  3WEH A;  4KPJ A;  3V66 A;  1DI1 A;  5DGN F;  3ZCD A;  2OGD A;  3Q30 A;  3N1W F;  2AET A;  3WCE A;  2O1O A;  2PS4 A;  3G4D A;  3Q2Q A;  4RNQ A;  5DJP F;  3WCI A;  3PKO A;  3N1V F;  4GAX A;  5H9D A;  5B0K A;  2Q58 A;  3N45 F;  1RQI A;  4NKF A;  2ZCS A;  5EAS A;  2Z4Y A;  3AQB B;  1KIZ A;  2E90 A;  4LFE A;  4DI5 A;  4DHD A;  1YHM A;  1N20 A;  3QQV A;  3BNX A;  4LOB A;  3WCH A;  3N5J F;  5JUZ F;  2F94 F;  3LOM A;  3P8L A;  3VJE A;  2DH4 A;  3SDR A;  3Q2Z A;  3P8R A;  1WL3 A;  4F6X A;  3NRI A;  4JZB A;  3PYB A;  3ICZ A;  3RYW A;  3KRO A;  1HX9 A;  2E8T A;  1YYQ A;  4KVD A;  2QIS A;  3ICM A;  3KBK A;  5DHK A;  2PS7 A;  2J1O A;  3Q1O A;  3NF2 A;  4LTZ A;  1YHK A;  3N0F A;  3KRC A;  3VJ9 A;  2Z52 A;  1V4K A;  5IMP A;  5ILZ A;  1YYU A;  3N5H F;  4KK2 A;  1EZF A;  2ZCR A;  5HN8 A;  2Z7I A;  5B0I A;  4XQS F;  4OKM A;  1YJ4 A;  3P5R A;  3EGT A;  4JZX A;  3WSB A;  3OAB A;  4KUX A;  5IKH A;  4KVW A;  1FPS A;  1HXA A;  5AYP A;  3WJK A;  5B01 A;  3KRC B;  3OAC B;  3AQC B;  4H5C F;  2Z4W A;  3WJN A;  4LFV F;  3KRF B;  3CP6 A;  1V4H A;  1YYR A;  3S4J A;  1VG6 A;  3P41 A;  3LSN A;  2Q80 A;  4RXD A;  2E91 A;  3WCM A;  5DZ2 A;  4DWG A;  3TFN A;  4QPF A;  3WEJ A;  4L2X F;  5EAT A;  4FJQ A;  2AZK A;  4LLS A;  4MC3 A;  3B7L A;  2F9K F;  5IVG A;  3G4F A;  2FTZ A;  5B02 A;  2PS8 A;  4DZW A;  4E1E A;  3S9V A;  3TS7 A;  1HXC A;  1UBW A;  3M01 A;  2E92 A;  1VG2 A;  2PS6 A;  3IPI A;  5E8H A;  2EWG A;  2E8U A;  4JVJ F;  4EA0 A;  3N46 F;  4HD1 A;  4LA6 A;  3M0G A;  4XQR F;  2F8C F;  4KWD A;  5A0J A;  4LTV A;  1YYS A;  5HN9 A;  5IL3 A;  5B03 A;  4MC8 A;  4DXJ A;  4OGU A;  5JA0 F;  4KQ5 A;  1V4J A;  1VG4 A;  4PVX F;  5B00 A;  3VJD A;  3UCA A;  5IMI A; 
#chains in the Genus database with same CATH topology
 3WEI A;  1WL2 A;  2Z4X A;  2J5C A;  4KKM A;  4LPG F;  4Q23 A;  3V1V A;  2OPM A;  5IK0 A;  3WC9 A;  3N6K F;  3APZ A;  3RBM A;  1JFA A;  4PVY F;  4LLT A;  3M9U A;  4RXE A;  3LGZ B;  3LEE A;  3N0G A;  5DGM F;  5A0K A;  1WKZ A;  2H8O A;  2ONH A;  4NFK F;  5KSX F;  2F8Z F;  4E9Z A;  2F7M F;  5IN8 A;  3ICK A;  2ZCQ A;  4KQU A;  3VJC A;  1UBV A;  5JV2 F;  4LXW A;  1N24 A;  3LZ9 A;  4P0X A;  2Z50 A;  1V4E A;  1HM7 A;  2OA6 A;  1N1B A;  3KRO B;  4DWB A;  4QXS F;  5CG5 A;  2Z78 A;  4WK5 A;  1RQJ A;  4MC0 A;  4P0V A;  3M00 A;  2Z4Z A;  4P0W A;  1YYT A;  5I1U A;  4GP2 A;  4F62 A;  3PH7 A;  3QKC A;  3LMD A;  5E8L A;  2E8W A;  5IMN A;  3BNY A;  1YV5 A;  3MAV A;  3KRA A;  1HM4 A;  4NFJ F;  3ZOU A;  4DEM F;  3PDE A;  4KVI A;  4LZC A;  4LFG A;  5A0I A;  5ILD A;  3OAB B;  5E8K A;  4GA3 A;  2ZY1 A;  4KVY A;  4N9U A;  3VJA A;  3ASX A;  3WEG A;  3WCJ A;  2AZL A;  3N3D A;  2E95 A;  5EAU A;  3LLW A;  4RXA A;  4E9U A;  5DJV F;  3WCG A;  1RTR A;  4OMH A;  1N1Z A;  3KRP A;  5ILJ A;  4UMJ A;  3WCC A;  4RYP A;  2VF6 A;  3SDU A;  4JXN A;  3ZL6 A;  2E8X A;  3DYH A;  3SDT A;  4KFA A;  2AZJ A;  3ZMB A;  2Q9Y A;  3V1X A;  3WJO A;  3DYG A;  1WMW A;  5IKA A;  5IM1 A;  1UBY A;  2ZEU A;  4LIX A;  3MZV A;  3KRP B;  4KPD A;  3CC9 A;  3NPK A;  2ZEV A;  1PS1 A;  3LVS A;  5DJR F;  3AQ0 A;  5JV1 F;  2Z4V A;  3ACY A;  5DGS F;  5IK6 A;  5ILI A;  3SAE A;  3LGK A;  3LJI A;  5DW7 A;  4OKZ A;  5C05 A;  3ADZ A;  4ZQ8 A;  1JFG A;  2I19 A;  4KQS A;  3W7F A;  3WEK A;  2OPN A;  5DHI A;  3LK5 A;  4NG6 A;  4FP4 A;  5IL8 A;  5ER8 A;  4N1Z F;  4XQT F;  5B0J A;  3NPR A;  3P5P A;  3SDQ A;  3ICN A;  3EZ3 A;  4H5D F;  3M02 A;  3OYR A;  5ERN A;  5ILK A;  3RYE A;  2AEK A;  2ONG A;  3KB9 A;  3SDV A;  5ILH A;  4OMG A;  2F92 F;  1WL1 A;  5IK9 A;  2E94 A;  2AEL A;  3WCL A;  1N23 A;  4NFI F;  3DYF A;  3WE9 A;  2E8V A;  4EA2 A;  1KIY A;  5AEL A;  4LZ0 A;  5B0L A;  2ZCO A;  2P1C A;  3RMG A;  4NUA A;  5ERM A;  1WY0 A;  3TC1 A;  5ERO A;  2J1P A;  1HXG A;  4F6V A;  3AE0 A;  4LZ3 A;  3WCD A;  3OAC A;  4H5E F;  3KRF A;  4GP1 A;  5ILY A;  1UBX A;  4JYX A;  3WCA A;  3EFQ A;  3WCB A;  3LG5 A;  1YQ7 A;  4NKE A;  4RXC A;  3ACW A;  3WSA A;  1DGP A;  4K10 A;  4LUU A;  5DIQ F;  3N3L F;  3WCF A;  2FOR A;  5AFX A;  3TFP A;  3WEF A;  1ZW5 A;  3TFV A;  2Z7H A;  3VJ8 A;  3LDW A;  2RAH A;  5AHU B;  3CKE A;  4EA1 A;  5HNA A;  3ZMC A;  1YHL A;  4LPH F;  5JV0 F;  4JXY A;  1WL0 A;  2E93 A;  3KRA B;  5CG6 A;  1V4I A;  1VG7 A;  3PYA A;  5HN7 A;  3ID0 A;  1VG3 A;  2F89 F;  1N22 A;  5B0M A;  3N49 F;  2Q9Z A;  2E4O A;  3IBA A;  3ACX A;  1N21 A;  3VJB A;  2PS5 A;  4LA5 A;  3WEH A;  4KPJ A;  3V66 A;  1DI1 A;  5DGN F;  3ZCD A;  2OGD A;  3Q30 A;  3N1W F;  2AET A;  3WCE A;  2O1O A;  2PS4 A;  3G4D A;  3Q2Q A;  4RNQ A;  5DJP F;  3WCI A;  3PKO A;  3N1V F;  4GAX A;  5H9D A;  5B0K A;  2Q58 A;  3N45 F;  1RQI A;  4NKF A;  2ZCS A;  5EAS A;  2Z4Y A;  3AQB B;  1KIZ A;  2E90 A;  4LFE A;  4DI5 A;  4DHD A;  1YHM A;  1N20 A;  3QQV A;  3BNX A;  4LOB A;  3WCH A;  3N5J F;  5JUZ F;  2F94 F;  3LOM A;  3P8L A;  3VJE A;  2DH4 A;  3SDR A;  3Q2Z A;  3P8R A;  1WL3 A;  4F6X A;  3NRI A;  4JZB A;  3PYB A;  3ICZ A;  3RYW A;  3KRO A;  1HX9 A;  2E8T A;  1YYQ A;  4KVD A;  2QIS A;  3ICM A;  3KBK A;  5DHK A;  2PS7 A;  2J1O A;  3Q1O A;  3NF2 A;  4LTZ A;  1YHK A;  3N0F A;  3KRC A;  3VJ9 A;  2Z52 A;  1V4K A;  5IMP A;  5ILZ A;  1YYU A;  3N5H F;  4KK2 A;  1EZF A;  2ZCR A;  5HN8 A;  2Z7I A;  5B0I A;  4XQS F;  4OKM A;  1YJ4 A;  3P5R A;  3EGT A;  4JZX A;  3WSB A;  3OAB A;  4KUX A;  5IKH A;  4KVW A;  1FPS A;  1HXA A;  5AYP A;  3WJK A;  5B01 A;  3KRC B;  3OAC B;  3AQC B;  4H5C F;  2Z4W A;  3WJN A;  4LFV F;  3KRF B;  3CP6 A;  1V4H A;  1YYR A;  3S4J A;  1VG6 A;  3P41 A;  3LSN A;  2Q80 A;  4RXD A;  2E91 A;  3WCM A;  5DZ2 A;  4DWG A;  3TFN A;  4QPF A;  3WEJ A;  4L2X F;  5EAT A;  4FJQ A;  2AZK A;  4LLS A;  4MC3 A;  3B7L A;  2F9K F;  5IVG A;  3G4F A;  2FTZ A;  5B02 A;  2PS8 A;  4DZW A;  4E1E A;  3S9V A;  3TS7 A;  1HXC A;  1UBW A;  3M01 A;  2E92 A;  1VG2 A;  2PS6 A;  3IPI A;  5E8H A;  2EWG A;  2E8U A;  4JVJ F;  4EA0 A;  3N46 F;  4HD1 A;  4LA6 A;  3M0G A;  4XQR F;  2F8C F;  4KWD A;  5A0J A;  4LTV A;  1YYS A;  5HN9 A;  5IL3 A;  5B03 A;  4MC8 A;  4DXJ A;  4OGU A;  5JA0 F;  4KQ5 A;  1V4J A;  1VG4 A;  4PVX F;  5B00 A;  3VJD A;  3UCA A;  5IMI A; 
#chains in the Genus database with same CATH homology
 3WEI A;  1WL2 A;  2Z4X A;  2J5C A;  4KKM A;  4LPG F;  4Q23 A;  3V1V A;  2OPM A;  5IK0 A;  3WC9 A;  3N6K F;  3APZ A;  3RBM A;  1JFA A;  4PVY F;  4LLT A;  3M9U A;  4RXE A;  3LGZ B;  3LEE A;  3N0G A;  5DGM F;  5A0K A;  1WKZ A;  2H8O A;  2ONH A;  4NFK F;  5KSX F;  2F8Z F;  4E9Z A;  2F7M F;  5IN8 A;  3ICK A;  2ZCQ A;  4KQU A;  3VJC A;  1UBV A;  5JV2 F;  4LXW A;  1N24 A;  3LZ9 A;  4P0X A;  2Z50 A;  1V4E A;  1HM7 A;  2OA6 A;  1N1B A;  3KRO B;  4DWB A;  4QXS F;  5CG5 A;  2Z78 A;  4WK5 A;  1RQJ A;  4MC0 A;  4P0V A;  3M00 A;  2Z4Z A;  4P0W A;  1YYT A;  5I1U A;  4GP2 A;  4F62 A;  3PH7 A;  3QKC A;  3LMD A;  5E8L A;  2E8W A;  5IMN A;  3BNY A;  1YV5 A;  3MAV A;  3KRA A;  1HM4 A;  4NFJ F;  3ZOU A;  4DEM F;  3PDE A;  4KVI A;  4LZC A;  4LFG A;  5A0I A;  5ILD A;  3OAB B;  5E8K A;  4GA3 A;  2ZY1 A;  4KVY A;  4N9U A;  3VJA A;  3ASX A;  3WEG A;  3WCJ A;  2AZL A;  3N3D A;  2E95 A;  5EAU A;  3LLW A;  4RXA A;  4E9U A;  5DJV F;  3WCG A;  1RTR A;  4OMH A;  1N1Z A;  3KRP A;  5ILJ A;  4UMJ A;  3WCC A;  4RYP A;  2VF6 A;  3SDU A;  4JXN A;  3ZL6 A;  2E8X A;  3DYH A;  3SDT A;  4KFA A;  2AZJ A;  3ZMB A;  2Q9Y A;  3V1X A;  3WJO A;  3DYG A;  1WMW A;  5IKA A;  5IM1 A;  1UBY A;  2ZEU A;  4LIX A;  3MZV A;  3KRP B;  4KPD A;  3CC9 A;  3NPK A;  2ZEV A;  1PS1 A;  3LVS A;  5DJR F;  3AQ0 A;  5JV1 F;  2Z4V A;  3ACY A;  5DGS F;  5IK6 A;  5ILI A;  3SAE A;  3LGK A;  3LJI A;  5DW7 A;  4OKZ A;  5C05 A;  3ADZ A;  4ZQ8 A;  1JFG A;  2I19 A;  4KQS A;  3W7F A;  3WEK A;  2OPN A;  5DHI A;  3LK5 A;  4NG6 A;  4FP4 A;  5IL8 A;  5ER8 A;  4N1Z F;  4XQT F;  5B0J A;  3NPR A;  3P5P A;  3SDQ A;  3ICN A;  3EZ3 A;  4H5D F;  3M02 A;  3OYR A;  5ERN A;  5ILK A;  3RYE A;  2AEK A;  2ONG A;  3KB9 A;  3SDV A;  5ILH A;  4OMG A;  2F92 F;  1WL1 A;  5IK9 A;  2E94 A;  2AEL A;  3WCL A;  1N23 A;  4NFI F;  3DYF A;  3WE9 A;  2E8V A;  4EA2 A;  1KIY A;  5AEL A;  4LZ0 A;  5B0L A;  2ZCO A;  2P1C A;  3RMG A;  4NUA A;  5ERM A;  1WY0 A;  3TC1 A;  5ERO A;  2J1P A;  1HXG A;  4F6V A;  3AE0 A;  4LZ3 A;  3WCD A;  3OAC A;  4H5E F;  3KRF A;  4GP1 A;  5ILY A;  1UBX A;  4JYX A;  3WCA A;  3EFQ A;  3WCB A;  3LG5 A;  1YQ7 A;  4NKE A;  4RXC A;  3ACW A;  3WSA A;  1DGP A;  4K10 A;  4LUU A;  5DIQ F;  3N3L F;  3WCF A;  2FOR A;  5AFX A;  3TFP A;  3WEF A;  1ZW5 A;  3TFV A;  2Z7H A;  3VJ8 A;  3LDW A;  2RAH A;  5AHU B;  3CKE A;  4EA1 A;  5HNA A;  3ZMC A;  1YHL A;  4LPH F;  5JV0 F;  4JXY A;  1WL0 A;  2E93 A;  3KRA B;  5CG6 A;  1V4I A;  1VG7 A;  3PYA A;  5HN7 A;  3ID0 A;  1VG3 A;  2F89 F;  1N22 A;  5B0M A;  3N49 F;  2Q9Z A;  2E4O A;  3IBA A;  3ACX A;  1N21 A;  3VJB A;  2PS5 A;  4LA5 A;  3WEH A;  4KPJ A;  3V66 A;  1DI1 A;  5DGN F;  3ZCD A;  2OGD A;  3Q30 A;  3N1W F;  2AET A;  3WCE A;  2O1O A;  2PS4 A;  3G4D A;  3Q2Q A;  4RNQ A;  5DJP F;  3WCI A;  3PKO A;  3N1V F;  4GAX A;  5H9D A;  5B0K A;  2Q58 A;  3N45 F;  1RQI A;  4NKF A;  2ZCS A;  5EAS A;  2Z4Y A;  3AQB B;  1KIZ A;  2E90 A;  4LFE A;  4DI5 A;  4DHD A;  1YHM A;  1N20 A;  3QQV A;  3BNX A;  4LOB A;  3WCH A;  3N5J F;  5JUZ F;  2F94 F;  3LOM A;  3P8L A;  3VJE A;  2DH4 A;  3SDR A;  3Q2Z A;  3P8R A;  1WL3 A;  4F6X A;  3NRI A;  4JZB A;  3PYB A;  3ICZ A;  3RYW A;  3KRO A;  1HX9 A;  2E8T A;  1YYQ A;  4KVD A;  2QIS A;  3ICM A;  3KBK A;  5DHK A;  2PS7 A;  2J1O A;  3Q1O A;  3NF2 A;  4LTZ A;  1YHK A;  3N0F A;  3KRC A;  3VJ9 A;  2Z52 A;  1V4K A;  5IMP A;  5ILZ A;  1YYU A;  3N5H F;  4KK2 A;  1EZF A;  2ZCR A;  5HN8 A;  2Z7I A;  5B0I A;  4XQS F;  4OKM A;  1YJ4 A;  3P5R A;  3EGT A;  4JZX A;  3WSB A;  3OAB A;  4KUX A;  5IKH A;  4KVW A;  1FPS A;  1HXA A;  5AYP A;  3WJK A;  5B01 A;  3KRC B;  3OAC B;  3AQC B;  4H5C F;  2Z4W A;  3WJN A;  4LFV F;  3KRF B;  3CP6 A;  1V4H A;  1YYR A;  3S4J A;  1VG6 A;  3P41 A;  3LSN A;  2Q80 A;  4RXD A;  2E91 A;  3WCM A;  5DZ2 A;  4DWG A;  3TFN A;  4QPF A;  3WEJ A;  4L2X F;  5EAT A;  4FJQ A;  2AZK A;  4LLS A;  4MC3 A;  3B7L A;  2F9K F;  5IVG A;  3G4F A;  2FTZ A;  5B02 A;  2PS8 A;  4DZW A;  4E1E A;  3S9V A;  3TS7 A;  1HXC A;  1UBW A;  3M01 A;  2E92 A;  1VG2 A;  2PS6 A;  3IPI A;  5E8H A;  2EWG A;  2E8U A;  4JVJ F;  4EA0 A;  3N46 F;  4HD1 A;  4LA6 A;  3M0G A;  4XQR F;  2F8C F;  4KWD A;  5A0J A;  4LTV A;  1YYS A;  5HN9 A;  5IL3 A;  5B03 A;  4MC8 A;  4DXJ A;  4OGU A;  5JA0 F;  4KQ5 A;  1V4J A;  1VG4 A;  4PVX F;  5B00 A;  3VJD A;  3UCA A;  5IMI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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