4F6VA

Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1034, mg2+ and fmp.
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
284
structure length
281
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
molecule keywords Dehydrosqualene synthase
total genus 114
structure length 281
sequence length 284
ec nomenclature ec 2.5.1.96: 4,4'-diapophytoene synthase.
pdb deposition date 2012-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4f6vA00
5IKAA 4E9UA 1V4HA 4Q23A 5A0JA 3N0GA 3WCDA 3WEJA 1HXAA 4JXNA 5AFXA 3P5PA 3OACB 4KVYA 1VG2A 4LUUA 4LZ3A 2Z78A 5ERNA 3LMDA 5DGSF 5IVGA 1PS1A 4KUXA 3ZMBA 2OPNA 5EASA 5HN8A 3VJAA 1V4IA 3VJCA 3MAVA 4L2XF 4FP4A 3OABA 3M9UA 4DXJA 5ILKA 2J5CA 3S4JA 3LVSA 5DIQF 4P0XA 2E8XA 5EROA 3WSBA 5IKHA 4FJQA 3ID0A 5IMPA 2E90A 4OKMA 3Q2QA 4LZ0A 5JUZF 2VF6A 3VJ8A 4KKMA 1VG6A 5IL3A 4EA1A 3WEGA 2P1CA 3M01A 2ZEUA 1WL1A 4EA0A 2PS7A 1JFGA 3EFQA 1VG3A 4NKEA 2Z4VA 3LZ9A 4PVXF 4LPGF 4N1ZF 4OKZA 4N9UA 4KPDA 4P0WA 3G4DA 1YYSA 5IK0A 4GAXA 4KWDA 5ILZA 3ICNA 3ICMA 4XQRF 3B7LA 4H5CF 4MC3A 5B02A 3ICKA 2E94A 3WEFA 2E8TA 4XQTF 3WCCA 4KQ5A 1JFAA 5IM1A 4QPFA 5B03A 2ONHA 3Q2ZA 3M00A 3LLWA 3ASXA 3NF2A 5JV0F 4K10A 5B0LA 3N46F 2AZKA 3ZMCA 1KIZA 3CP6A 3EGTA 3M02A 1RQIA 3LEEA 5B00A 4GP1A 2ZEVA 4LOBA 5EAUA 4DWGA 3OABB 4LA5A 1YYRA 5ILJA 3KRCA 3N6KF 1EZFA 2Z7HA 4NFIF 5IK9A 4LLTA 3P41A 3VJ9A 3RMGA 3Q30A 3ZL6A 4E9ZA 2OPMA 1HXGA 2PS5A 3RYWA 5ILIA 3PKOA 5CG5A 3SDRA 3WCEA 4RNQA 3ACXA 2FTZA 4MC8A 2E93A 2ZCQA 2ZY1A 1V4JA 1HM4A 5DHKA 3RBMA 3TFVA 5E8HA 3WJOA 4KQSA 1V4EA 4KVWA 2Z52A 3NPKA 3WCJA 3V1VA 3AQ0A 1V4KA 4F6VA 4LTZA 3CC9A 3KROA 2ONGA 1HX9A 2Z50A 4LFEA 1UBXA 2F7MF 3KBKA 5IK6A 1KIYA 1YHKA 4NKFA 3WCIA 3P8RA 4JZXA 5HN9A 3TS7A 2EWGA 3N3LF 4DEMF 4LPHF 3LGZB 2F89F 3KRAB 1WMWA 2RAHA 3N1WF 4JYXA 4KVDA 2ZCSA 4RXEA 3KRPB 1YHMA 3PYBA 3DYGA 5H9DA 3PH7A 4LFGA 4MC0A 2Z7IA 4DWBA 1UBWA 4LZCA 3LG5A 4LIXA 3VJBA 3QQVA 3IPIA 3KRFA 3SDVA 3BNXA 1N22A 5ILDA 4PVYF 3KB9A 4OMHA 4OGUA 3PDEA 2F9KF 5B0MA 2E8WA 5C05A 2AELA 3KRCB 4F62A 4DHDA 4LXWA 4EA2A 5E8LA 3CKEA 3ADZA 2F94F 4JVJF 5EATA 2DH4A 3VJDA 2Z4WA 1FPSA 3AQBB 1ZW5A 4GA3A 4KK2A 2Z4XA 2Q9YA 5ERMA 1N1ZA 2F8CF 4KVIA 5JV1F 1N20A 3KROB 3IBAA 4LA6A 3W7FA 2F92F 2J1OA 2AZJA 3V66A 2ZCOA 3ICZA 2Z4ZA 3P5RA 3WJNA 5A0IA 2Q58A 5ILHA 5JA0F 1YQ7A 3M0GA 4LLSA 1HM7A 3N3DA 3MZVA 3SAEA 1WY0A 1YYUA 3BNYA 5IL8A 5DGNF 3ACYA 3QKCA 3SDQA 5A0KA 1WL2A 4WK5A 1WL0A 3APZA 1YYQA 5HN7A 4NFKF 1YYTA 1N1BA 3ZCDA 5DHIA 5I1UA 5AELA 3WE9A 3WCHA 2ZCRA 5AYPA 1UBYA 3UCAA 1HXCA 3LOMA 4LTVA 5B0JA 3RYEA 2Q80A 4F6XA 4DI5A 3TFPA 2O1OA 2QISA 5B0KA 5DJPF 4RXCA 2AETA 3ACWA 4LFVF 4XQSF 3WEHA 4JXYA 5IMIA 3NRIA 3SDTA 1RQJA 4E1EA 3N49F 4JZBA 4NG6A 3TFNA 3N45F 5JV2F 2H8OA 5ILYA 3ZOUA 3N5HF 4RXAA 4KQUA 4KPJA 2Z4YA 4NUAA 4ZQ8A 3WCMA 1N23A 5ER8A 5DZ2A 1WL3A 5KSXF 1DI1A 5DJVF 3LDWA 3LSNA 3LGKA 2OGDA 3S9VA 3N1VF 5HNAA 3TC1A 3PYAA 2PS6A 4GP2A 5DGMF 1YV5A 4QXSF 5B0IA 3OACA 4H5EF 3AE0A 5IN8A 1UBVA 3EZ3A 2Q9ZA 4H5DF 3WSAA 3LK5A 2AZLA 4DZWA 4RYPA 4RXDA 2PS8A 5E8KA 3WCFA 5DJRF 1VG7A 3WCLA 3P8LA 1RTRA 3LJIA 3Q1OA 3SDUA 4P0VA 3VJEA 2I19A 3N5JF 3NPRA 1N24A 3V1XA 5CG6A 3KRAA 2AEKA 3OYRA 2E8UA 2OA6A 1DGPA 1N21A 3KRPA 4OMGA 2E92A 2PS4A 3WEIA 4HD1A 2J1PA 4UMJA 3WC9A 2E8VA 5IMNA 3WCGA 3WEKA 2FORA 5B01A 3DYHA 1YHLA 4KFAA 3DYFA 2E95A 2E91A 3WCBA 3N0FA 1VG4A 3WJKA 3WCAA 2E4OA 4NFJF 5DW7A 3AQCB 2F8ZF 1YJ4A 3G4FA 1WKZA 3KRFB 5AHUB
chains in the Genus database with same CATH superfamily
5IKAA 4E9UA 1V4HA 4Q23A 5A0JA 3N0GA 3WCDA 3WEJA 1HXAA 4JXNA 5AFXA 3P5PA 3OACB 4KVYA 1VG2A 4LUUA 4LZ3A 2Z78A 5ERNA 3LMDA 5DGSF 5IVGA 1PS1A 4KUXA 3ZMBA 2OPNA 5EASA 5HN8A 3VJAA 1V4IA 3VJCA 3MAVA 4L2XF 4FP4A 3OABA 3M9UA 4DXJA 5ILKA 2J5CA 3S4JA 3LVSA 5DIQF 4P0XA 2E8XA 5EROA 3WSBA 5IKHA 4FJQA 3ID0A 5IMPA 2E90A 4OKMA 3Q2QA 4LZ0A 5JUZF 2VF6A 3VJ8A 4KKMA 1VG6A 5IL3A 4EA1A 3WEGA 2P1CA 3M01A 2ZEUA 1WL1A 4EA0A 2PS7A 1JFGA 3EFQA 1VG3A 4NKEA 2Z4VA 3LZ9A 4PVXF 4LPGF 4N1ZF 4OKZA 4N9UA 4KPDA 4P0WA 3G4DA 1YYSA 5IK0A 4GAXA 4KWDA 5ILZA 3ICNA 3ICMA 4XQRF 3B7LA 4H5CF 4MC3A 5B02A 3ICKA 2E94A 3WEFA 2E8TA 4XQTF 3WCCA 4KQ5A 1JFAA 5IM1A 4QPFA 5B03A 2ONHA 3Q2ZA 3M00A 3LLWA 3ASXA 3NF2A 5JV0F 4K10A 5B0LA 3N46F 2AZKA 3ZMCA 1KIZA 3CP6A 3EGTA 3M02A 1RQIA 3LEEA 5B00A 4GP1A 2ZEVA 4LOBA 5EAUA 4DWGA 3OABB 4LA5A 1YYRA 5ILJA 3KRCA 3N6KF 1EZFA 2Z7HA 4NFIF 5IK9A 4LLTA 3P41A 3VJ9A 3RMGA 3Q30A 3ZL6A 4E9ZA 2OPMA 1HXGA 2PS5A 3RYWA 5ILIA 3PKOA 5CG5A 3SDRA 3WCEA 4RNQA 3ACXA 2FTZA 4MC8A 2E93A 2ZCQA 2ZY1A 1V4JA 1HM4A 5DHKA 3RBMA 3TFVA 5E8HA 3WJOA 4KQSA 1V4EA 4KVWA 2Z52A 3NPKA 3WCJA 3V1VA 3AQ0A 1V4KA 4F6VA 4LTZA 3CC9A 3KROA 2ONGA 1HX9A 2Z50A 4LFEA 1UBXA 2F7MF 3KBKA 5IK6A 1KIYA 1YHKA 4NKFA 3WCIA 3P8RA 4JZXA 5HN9A 3TS7A 2EWGA 3N3LF 4DEMF 4LPHF 3LGZB 2F89F 3KRAB 1WMWA 2RAHA 3N1WF 4JYXA 4KVDA 2ZCSA 4RXEA 3KRPB 1YHMA 3PYBA 3DYGA 5H9DA 3PH7A 4LFGA 4MC0A 2Z7IA 4DWBA 1UBWA 4LZCA 3LG5A 4LIXA 3VJBA 3QQVA 3IPIA 3KRFA 3SDVA 3BNXA 1N22A 5ILDA 4PVYF 3KB9A 4OMHA 4OGUA 3PDEA 2F9KF 5B0MA 2E8WA 5C05A 2AELA 3KRCB 4F62A 4DHDA 4LXWA 4EA2A 5E8LA 3CKEA 3ADZA 2F94F 4JVJF 5EATA 2DH4A 3VJDA 2Z4WA 1FPSA 3AQBB 1ZW5A 4GA3A 4KK2A 2Z4XA 2Q9YA 5ERMA 1N1ZA 2F8CF 4KVIA 5JV1F 1N20A 3KROB 3IBAA 4LA6A 3W7FA 2F92F 2J1OA 2AZJA 3V66A 2ZCOA 3ICZA 2Z4ZA 3P5RA 3WJNA 5A0IA 2Q58A 5ILHA 5JA0F 1YQ7A 3M0GA 4LLSA 1HM7A 3N3DA 3MZVA 3SAEA 1WY0A 1YYUA 3BNYA 5IL8A 5DGNF 3ACYA 3QKCA 3SDQA 5A0KA 1WL2A 4WK5A 1WL0A 3APZA 1YYQA 5HN7A 4NFKF 1YYTA 1N1BA 3ZCDA 5DHIA 5I1UA 5AELA 3WE9A 3WCHA 2ZCRA 5AYPA 1UBYA 3UCAA 1HXCA 3LOMA 4LTVA 5B0JA 3RYEA 2Q80A 4F6XA 4DI5A 3TFPA 2O1OA 2QISA 5B0KA 5DJPF 4RXCA 2AETA 3ACWA 4LFVF 4XQSF 3WEHA 4JXYA 5IMIA 3NRIA 3SDTA 1RQJA 4E1EA 3N49F 4JZBA 4NG6A 3TFNA 3N45F 5JV2F 2H8OA 5ILYA 3ZOUA 3N5HF 4RXAA 4KQUA 4KPJA 2Z4YA 4NUAA 4ZQ8A 3WCMA 1N23A 5ER8A 5DZ2A 1WL3A 5KSXF 1DI1A 5DJVF 3LDWA 3LSNA 3LGKA 2OGDA 3S9VA 3N1VF 5HNAA 3TC1A 3PYAA 2PS6A 4GP2A 5DGMF 1YV5A 4QXSF 5B0IA 3OACA 4H5EF 3AE0A 5IN8A 1UBVA 3EZ3A 2Q9ZA 4H5DF 3WSAA 3LK5A 2AZLA 4DZWA 4RYPA 4RXDA 2PS8A 5E8KA 3WCFA 5DJRF 1VG7A 3WCLA 3P8LA 1RTRA 3LJIA 3Q1OA 3SDUA 4P0VA 3VJEA 2I19A 3N5JF 3NPRA 1N24A 3V1XA 5CG6A 3KRAA 2AEKA 3OYRA 2E8UA 2OA6A 1DGPA 1N21A 3KRPA 4OMGA 2E92A 2PS4A 3WEIA 4HD1A 2J1PA 4UMJA 3WC9A 2E8VA 5IMNA 3WCGA 3WEKA 2FORA 5B01A 3DYHA 1YHLA 4KFAA 3DYFA 2E95A 2E91A 3WCBA 3N0FA 1VG4A 3WJKA 3WCAA 2E4OA 4NFJF 5DW7A 3AQCB 2F8ZF 1YJ4A 3G4FA 1WKZA 3KRFB 5AHUB
chains in the Genus database with same CATH topology
5IKAA 4E9UA 1V4HA 4Q23A 5A0JA 3N0GA 3WCDA 3WEJA 1HXAA 4JXNA 5AFXA 3P5PA 3OACB 4KVYA 1VG2A 4LUUA 4LZ3A 2Z78A 5ERNA 3LMDA 5DGSF 5IVGA 1PS1A 4KUXA 3ZMBA 2OPNA 5EASA 5HN8A 3VJAA 1V4IA 3VJCA 3MAVA 4L2XF 4FP4A 3OABA 3M9UA 4DXJA 5ILKA 2J5CA 3S4JA 3LVSA 5DIQF 4P0XA 2E8XA 5EROA 3WSBA 5IKHA 4FJQA 3ID0A 5IMPA 2E90A 4OKMA 3Q2QA 4LZ0A 5JUZF 2VF6A 3VJ8A 4KKMA 1VG6A 5IL3A 4EA1A 3WEGA 2P1CA 3M01A 2ZEUA 1WL1A 4EA0A 2PS7A 1JFGA 3EFQA 1VG3A 4NKEA 2Z4VA 3LZ9A 4PVXF 4LPGF 4N1ZF 4OKZA 4N9UA 4KPDA 4P0WA 3G4DA 1YYSA 5IK0A 4GAXA 4KWDA 5ILZA 3ICNA 3ICMA 4XQRF 3B7LA 4H5CF 4MC3A 5B02A 3ICKA 2E94A 3WEFA 2E8TA 4XQTF 3WCCA 4KQ5A 1JFAA 5IM1A 4QPFA 5B03A 2ONHA 3Q2ZA 3M00A 3LLWA 3ASXA 3NF2A 5JV0F 4K10A 5B0LA 3N46F 2AZKA 3ZMCA 1KIZA 3CP6A 3EGTA 3M02A 1RQIA 3LEEA 5B00A 4GP1A 2ZEVA 4LOBA 5EAUA 4DWGA 3OABB 4LA5A 1YYRA 5ILJA 3KRCA 3N6KF 1EZFA 2Z7HA 4NFIF 5IK9A 4LLTA 3P41A 3VJ9A 3RMGA 3Q30A 3ZL6A 4E9ZA 2OPMA 1HXGA 2PS5A 3RYWA 5ILIA 3PKOA 5CG5A 3SDRA 3WCEA 4RNQA 3ACXA 2FTZA 4MC8A 2E93A 2ZCQA 2ZY1A 1V4JA 1HM4A 5DHKA 3RBMA 3TFVA 5E8HA 3WJOA 4KQSA 1V4EA 4KVWA 2Z52A 3NPKA 3WCJA 3V1VA 3AQ0A 1V4KA 4F6VA 4LTZA 3CC9A 3KROA 2ONGA 1HX9A 2Z50A 4LFEA 1UBXA 2F7MF 3KBKA 5IK6A 1KIYA 1YHKA 4NKFA 3WCIA 3P8RA 4JZXA 5HN9A 3TS7A 2EWGA 3N3LF 4DEMF 4LPHF 3LGZB 2F89F 3KRAB 1WMWA 2RAHA 3N1WF 4JYXA 4KVDA 2ZCSA 4RXEA 3KRPB 1YHMA 3PYBA 3DYGA 5H9DA 3PH7A 4LFGA 4MC0A 2Z7IA 4DWBA 1UBWA 4LZCA 3LG5A 4LIXA 3VJBA 3QQVA 3IPIA 3KRFA 3SDVA 3BNXA 1N22A 5ILDA 4PVYF 3KB9A 4OMHA 4OGUA 3PDEA 2F9KF 5B0MA 2E8WA 5C05A 2AELA 3KRCB 4F62A 4DHDA 4LXWA 4EA2A 5E8LA 3CKEA 3ADZA 2F94F 4JVJF 5EATA 2DH4A 3VJDA 2Z4WA 1FPSA 3AQBB 1ZW5A 4GA3A 4KK2A 2Z4XA 2Q9YA 5ERMA 1N1ZA 2F8CF 4KVIA 5JV1F 1N20A 3KROB 3IBAA 4LA6A 3W7FA 2F92F 2J1OA 2AZJA 3V66A 2ZCOA 3ICZA 2Z4ZA 3P5RA 3WJNA 5A0IA 2Q58A 5ILHA 5JA0F 1YQ7A 3M0GA 4LLSA 1HM7A 3N3DA 3MZVA 3SAEA 1WY0A 1YYUA 3BNYA 5IL8A 5DGNF 3ACYA 3QKCA 3SDQA 5A0KA 1WL2A 4WK5A 1WL0A 3APZA 1YYQA 5HN7A 4NFKF 1YYTA 1N1BA 3ZCDA 5DHIA 5I1UA 5AELA 3WE9A 3WCHA 2ZCRA 5AYPA 1UBYA 3UCAA 1HXCA 3LOMA 4LTVA 5B0JA 3RYEA 2Q80A 4F6XA 4DI5A 3TFPA 2O1OA 2QISA 5B0KA 5DJPF 4RXCA 2AETA 3ACWA 4LFVF 4XQSF 3WEHA 4JXYA 5IMIA 3NRIA 3SDTA 1RQJA 4E1EA 3N49F 4JZBA 4NG6A 3TFNA 3N45F 5JV2F 2H8OA 5ILYA 3ZOUA 3N5HF 4RXAA 4KQUA 4KPJA 2Z4YA 4NUAA 4ZQ8A 3WCMA 1N23A 5ER8A 5DZ2A 1WL3A 5KSXF 1DI1A 5DJVF 3LDWA 3LSNA 3LGKA 2OGDA 3S9VA 3N1VF 5HNAA 3TC1A 3PYAA 2PS6A 4GP2A 5DGMF 1YV5A 4QXSF 5B0IA 3OACA 4H5EF 3AE0A 5IN8A 1UBVA 3EZ3A 2Q9ZA 4H5DF 3WSAA 3LK5A 2AZLA 4DZWA 4RYPA 4RXDA 2PS8A 5E8KA 3WCFA 5DJRF 1VG7A 3WCLA 3P8LA 1RTRA 3LJIA 3Q1OA 3SDUA 4P0VA 3VJEA 2I19A 3N5JF 3NPRA 1N24A 3V1XA 5CG6A 3KRAA 2AEKA 3OYRA 2E8UA 2OA6A 1DGPA 1N21A 3KRPA 4OMGA 2E92A 2PS4A 3WEIA 4HD1A 2J1PA 4UMJA 3WC9A 2E8VA 5IMNA 3WCGA 3WEKA 2FORA 5B01A 3DYHA 1YHLA 4KFAA 3DYFA 2E95A 2E91A 3WCBA 3N0FA 1VG4A 3WJKA 3WCAA 2E4OA 4NFJF 5DW7A 3AQCB 2F8ZF 1YJ4A 3G4FA 1WKZA 3KRFB 5AHUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IKA A;  4E9U A;  1V4H A;  4Q23 A;  5A0J A;  3N0G A;  3WCD A;  3WEJ A;  1HXA A;  4JXN A;  5AFX A;  3P5P A;  3OAC B;  4KVY A;  1VG2 A;  4LUU A;  4LZ3 A;  2Z78 A;  5ERN A;  3LMD A;  5DGS F;  5IVG A;  1PS1 A;  4KUX A;  3ZMB A;  2OPN A;  5EAS A;  5HN8 A;  3VJA A;  1V4I A;  3VJC A;  3MAV A;  4L2X F;  4FP4 A;  3OAB A;  3M9U A;  4DXJ A;  5ILK A;  2J5C A;  3S4J A;  3LVS A;  5DIQ F;  4P0X A;  2E8X A;  5ERO A;  3WSB A;  5IKH A;  4FJQ A;  3ID0 A;  5IMP A;  2E90 A;  4OKM A;  3Q2Q A;  4LZ0 A;  5JUZ F;  2VF6 A;  3VJ8 A;  4KKM A;  1VG6 A;  5IL3 A;  4EA1 A;  3WEG A;  2P1C A;  3M01 A;  2ZEU A;  1WL1 A;  4EA0 A;  2PS7 A;  1JFG A;  3EFQ A;  1VG3 A;  4NKE A;  2Z4V A;  3LZ9 A;  4PVX F;  4LPG F;  4N1Z F;  4OKZ A;  4N9U A;  4KPD A;  4P0W A;  3G4D A;  1YYS A;  5IK0 A;  4GAX A;  4KWD A;  5ILZ A;  3ICN A;  3ICM A;  4XQR F;  3B7L A;  4H5C F;  4MC3 A;  5B02 A;  3ICK A;  2E94 A;  3WEF A;  2E8T A;  4XQT F;  3WCC A;  4KQ5 A;  1JFA A;  5IM1 A;  4QPF A;  5B03 A;  2ONH A;  3Q2Z A;  3M00 A;  3LLW A;  3ASX A;  3NF2 A;  5JV0 F;  4K10 A;  5B0L A;  3N46 F;  2AZK A;  3ZMC A;  1KIZ A;  3CP6 A;  3EGT A;  3M02 A;  1RQI A;  3LEE A;  5B00 A;  4GP1 A;  2ZEV A;  4LOB A;  5EAU A;  4DWG A;  3OAB B;  4LA5 A;  1YYR A;  5ILJ A;  3KRC A;  3N6K F;  1EZF A;  2Z7H A;  4NFI F;  5IK9 A;  4LLT A;  3P41 A;  3VJ9 A;  3RMG A;  3Q30 A;  3ZL6 A;  4E9Z A;  2OPM A;  1HXG A;  2PS5 A;  3RYW A;  5ILI A;  3PKO A;  5CG5 A;  3SDR A;  3WCE A;  4RNQ A;  3ACX A;  2FTZ A;  4MC8 A;  2E93 A;  2ZCQ A;  2ZY1 A;  1V4J A;  1HM4 A;  5DHK A;  3RBM A;  3TFV A;  5E8H A;  3WJO A;  4KQS A;  1V4E A;  4KVW A;  2Z52 A;  3NPK A;  3WCJ A;  3V1V A;  3AQ0 A;  1V4K A;  4F6V A;  4LTZ A;  3CC9 A;  3KRO A;  2ONG A;  1HX9 A;  2Z50 A;  4LFE A;  1UBX A;  2F7M F;  3KBK A;  5IK6 A;  1KIY A;  1YHK A;  4NKF A;  3WCI A;  3P8R A;  4JZX A;  5HN9 A;  3TS7 A;  2EWG A;  3N3L F;  4DEM F;  4LPH F;  3LGZ B;  2F89 F;  3KRA B;  1WMW A;  2RAH A;  3N1W F;  4JYX A;  4KVD A;  2ZCS A;  4RXE A;  3KRP B;  1YHM A;  3PYB A;  3DYG A;  5H9D A;  3PH7 A;  4LFG A;  4MC0 A;  2Z7I A;  4DWB A;  1UBW A;  4LZC A;  3LG5 A;  4LIX A;  3VJB A;  3QQV A;  3IPI A;  3KRF A;  3SDV A;  3BNX A;  1N22 A;  5ILD A;  4PVY F;  3KB9 A;  4OMH A;  4OGU A;  3PDE A;  2F9K F;  5B0M A;  2E8W A;  5C05 A;  2AEL A;  3KRC B;  4F62 A;  4DHD A;  4LXW A;  4EA2 A;  5E8L A;  3CKE A;  3ADZ A;  2F94 F;  4JVJ F;  5EAT A;  2DH4 A;  3VJD A;  2Z4W A;  1FPS A;  3AQB B;  1ZW5 A;  4GA3 A;  4KK2 A;  2Z4X A;  2Q9Y A;  5ERM A;  1N1Z A;  2F8C F;  4KVI A;  5JV1 F;  1N20 A;  3KRO B;  3IBA A;  4LA6 A;  3W7F A;  2F92 F;  2J1O A;  2AZJ A;  3V66 A;  2ZCO A;  3ICZ A;  2Z4Z A;  3P5R A;  3WJN A;  5A0I A;  2Q58 A;  5ILH A;  5JA0 F;  1YQ7 A;  3M0G A;  4LLS A;  1HM7 A;  3N3D A;  3MZV A;  3SAE A;  1WY0 A;  1YYU A;  3BNY A;  5IL8 A;  5DGN F;  3ACY A;  3QKC A;  3SDQ A;  5A0K A;  1WL2 A;  4WK5 A;  1WL0 A;  3APZ A;  1YYQ A;  5HN7 A;  4NFK F;  1YYT A;  1N1B A;  3ZCD A;  5DHI A;  5I1U A;  5AEL A;  3WE9 A;  3WCH A;  2ZCR A;  5AYP A;  1UBY A;  3UCA A;  1HXC A;  3LOM A;  4LTV A;  5B0J A;  3RYE A;  2Q80 A;  4F6X A;  4DI5 A;  3TFP A;  2O1O A;  2QIS A;  5B0K A;  5DJP F;  4RXC A;  2AET A;  3ACW A;  4LFV F;  4XQS F;  3WEH A;  4JXY A;  5IMI A;  3NRI A;  3SDT A;  1RQJ A;  4E1E A;  3N49 F;  4JZB A;  4NG6 A;  3TFN A;  3N45 F;  5JV2 F;  2H8O A;  5ILY A;  3ZOU A;  3N5H F;  4RXA A;  4KQU A;  4KPJ A;  2Z4Y A;  4NUA A;  4ZQ8 A;  3WCM A;  1N23 A;  5ER8 A;  5DZ2 A;  1WL3 A;  5KSX F;  1DI1 A;  5DJV F;  3LDW A;  3LSN A;  3LGK A;  2OGD A;  3S9V A;  3N1V F;  5HNA A;  3TC1 A;  3PYA A;  2PS6 A;  4GP2 A;  5DGM F;  1YV5 A;  4QXS F;  5B0I A;  3OAC A;  4H5E F;  3AE0 A;  5IN8 A;  1UBV A;  3EZ3 A;  2Q9Z A;  4H5D F;  3WSA A;  3LK5 A;  2AZL A;  4DZW A;  4RYP A;  4RXD A;  2PS8 A;  5E8K A;  3WCF A;  5DJR F;  1VG7 A;  3WCL A;  3P8L A;  1RTR A;  3LJI A;  3Q1O A;  3SDU A;  4P0V A;  3VJE A;  2I19 A;  3N5J F;  3NPR A;  1N24 A;  3V1X A;  5CG6 A;  3KRA A;  2AEK A;  3OYR A;  2E8U A;  2OA6 A;  1DGP A;  1N21 A;  3KRP A;  4OMG A;  2E92 A;  2PS4 A;  3WEI A;  4HD1 A;  2J1P A;  4UMJ A;  3WC9 A;  2E8V A;  5IMN A;  3WCG A;  3WEK A;  2FOR A;  5B01 A;  3DYH A;  1YHL A;  4KFA A;  3DYF A;  2E95 A;  2E91 A;  3WCB A;  3N0F A;  1VG4 A;  3WJK A;  3WCA A;  2E4O A;  4NFJ F;  5DW7 A;  3AQC B;  2F8Z F;  1YJ4 A;  3G4F A;  1WKZ A;  3KRF B;  5AHU B; 
#chains in the Genus database with same CATH topology
 5IKA A;  4E9U A;  1V4H A;  4Q23 A;  5A0J A;  3N0G A;  3WCD A;  3WEJ A;  1HXA A;  4JXN A;  5AFX A;  3P5P A;  3OAC B;  4KVY A;  1VG2 A;  4LUU A;  4LZ3 A;  2Z78 A;  5ERN A;  3LMD A;  5DGS F;  5IVG A;  1PS1 A;  4KUX A;  3ZMB A;  2OPN A;  5EAS A;  5HN8 A;  3VJA A;  1V4I A;  3VJC A;  3MAV A;  4L2X F;  4FP4 A;  3OAB A;  3M9U A;  4DXJ A;  5ILK A;  2J5C A;  3S4J A;  3LVS A;  5DIQ F;  4P0X A;  2E8X A;  5ERO A;  3WSB A;  5IKH A;  4FJQ A;  3ID0 A;  5IMP A;  2E90 A;  4OKM A;  3Q2Q A;  4LZ0 A;  5JUZ F;  2VF6 A;  3VJ8 A;  4KKM A;  1VG6 A;  5IL3 A;  4EA1 A;  3WEG A;  2P1C A;  3M01 A;  2ZEU A;  1WL1 A;  4EA0 A;  2PS7 A;  1JFG A;  3EFQ A;  1VG3 A;  4NKE A;  2Z4V A;  3LZ9 A;  4PVX F;  4LPG F;  4N1Z F;  4OKZ A;  4N9U A;  4KPD A;  4P0W A;  3G4D A;  1YYS A;  5IK0 A;  4GAX A;  4KWD A;  5ILZ A;  3ICN A;  3ICM A;  4XQR F;  3B7L A;  4H5C F;  4MC3 A;  5B02 A;  3ICK A;  2E94 A;  3WEF A;  2E8T A;  4XQT F;  3WCC A;  4KQ5 A;  1JFA A;  5IM1 A;  4QPF A;  5B03 A;  2ONH A;  3Q2Z A;  3M00 A;  3LLW A;  3ASX A;  3NF2 A;  5JV0 F;  4K10 A;  5B0L A;  3N46 F;  2AZK A;  3ZMC A;  1KIZ A;  3CP6 A;  3EGT A;  3M02 A;  1RQI A;  3LEE A;  5B00 A;  4GP1 A;  2ZEV A;  4LOB A;  5EAU A;  4DWG A;  3OAB B;  4LA5 A;  1YYR A;  5ILJ A;  3KRC A;  3N6K F;  1EZF A;  2Z7H A;  4NFI F;  5IK9 A;  4LLT A;  3P41 A;  3VJ9 A;  3RMG A;  3Q30 A;  3ZL6 A;  4E9Z A;  2OPM A;  1HXG A;  2PS5 A;  3RYW A;  5ILI A;  3PKO A;  5CG5 A;  3SDR A;  3WCE A;  4RNQ A;  3ACX A;  2FTZ A;  4MC8 A;  2E93 A;  2ZCQ A;  2ZY1 A;  1V4J A;  1HM4 A;  5DHK A;  3RBM A;  3TFV A;  5E8H A;  3WJO A;  4KQS A;  1V4E A;  4KVW A;  2Z52 A;  3NPK A;  3WCJ A;  3V1V A;  3AQ0 A;  1V4K A;  4F6V A;  4LTZ A;  3CC9 A;  3KRO A;  2ONG A;  1HX9 A;  2Z50 A;  4LFE A;  1UBX A;  2F7M F;  3KBK A;  5IK6 A;  1KIY A;  1YHK A;  4NKF A;  3WCI A;  3P8R A;  4JZX A;  5HN9 A;  3TS7 A;  2EWG A;  3N3L F;  4DEM F;  4LPH F;  3LGZ B;  2F89 F;  3KRA B;  1WMW A;  2RAH A;  3N1W F;  4JYX A;  4KVD A;  2ZCS A;  4RXE A;  3KRP B;  1YHM A;  3PYB A;  3DYG A;  5H9D A;  3PH7 A;  4LFG A;  4MC0 A;  2Z7I A;  4DWB A;  1UBW A;  4LZC A;  3LG5 A;  4LIX A;  3VJB A;  3QQV A;  3IPI A;  3KRF A;  3SDV A;  3BNX A;  1N22 A;  5ILD A;  4PVY F;  3KB9 A;  4OMH A;  4OGU A;  3PDE A;  2F9K F;  5B0M A;  2E8W A;  5C05 A;  2AEL A;  3KRC B;  4F62 A;  4DHD A;  4LXW A;  4EA2 A;  5E8L A;  3CKE A;  3ADZ A;  2F94 F;  4JVJ F;  5EAT A;  2DH4 A;  3VJD A;  2Z4W A;  1FPS A;  3AQB B;  1ZW5 A;  4GA3 A;  4KK2 A;  2Z4X A;  2Q9Y A;  5ERM A;  1N1Z A;  2F8C F;  4KVI A;  5JV1 F;  1N20 A;  3KRO B;  3IBA A;  4LA6 A;  3W7F A;  2F92 F;  2J1O A;  2AZJ A;  3V66 A;  2ZCO A;  3ICZ A;  2Z4Z A;  3P5R A;  3WJN A;  5A0I A;  2Q58 A;  5ILH A;  5JA0 F;  1YQ7 A;  3M0G A;  4LLS A;  1HM7 A;  3N3D A;  3MZV A;  3SAE A;  1WY0 A;  1YYU A;  3BNY A;  5IL8 A;  5DGN F;  3ACY A;  3QKC A;  3SDQ A;  5A0K A;  1WL2 A;  4WK5 A;  1WL0 A;  3APZ A;  1YYQ A;  5HN7 A;  4NFK F;  1YYT A;  1N1B A;  3ZCD A;  5DHI A;  5I1U A;  5AEL A;  3WE9 A;  3WCH A;  2ZCR A;  5AYP A;  1UBY A;  3UCA A;  1HXC A;  3LOM A;  4LTV A;  5B0J A;  3RYE A;  2Q80 A;  4F6X A;  4DI5 A;  3TFP A;  2O1O A;  2QIS A;  5B0K A;  5DJP F;  4RXC A;  2AET A;  3ACW A;  4LFV F;  4XQS F;  3WEH A;  4JXY A;  5IMI A;  3NRI A;  3SDT A;  1RQJ A;  4E1E A;  3N49 F;  4JZB A;  4NG6 A;  3TFN A;  3N45 F;  5JV2 F;  2H8O A;  5ILY A;  3ZOU A;  3N5H F;  4RXA A;  4KQU A;  4KPJ A;  2Z4Y A;  4NUA A;  4ZQ8 A;  3WCM A;  1N23 A;  5ER8 A;  5DZ2 A;  1WL3 A;  5KSX F;  1DI1 A;  5DJV F;  3LDW A;  3LSN A;  3LGK A;  2OGD A;  3S9V A;  3N1V F;  5HNA A;  3TC1 A;  3PYA A;  2PS6 A;  4GP2 A;  5DGM F;  1YV5 A;  4QXS F;  5B0I A;  3OAC A;  4H5E F;  3AE0 A;  5IN8 A;  1UBV A;  3EZ3 A;  2Q9Z A;  4H5D F;  3WSA A;  3LK5 A;  2AZL A;  4DZW A;  4RYP A;  4RXD A;  2PS8 A;  5E8K A;  3WCF A;  5DJR F;  1VG7 A;  3WCL A;  3P8L A;  1RTR A;  3LJI A;  3Q1O A;  3SDU A;  4P0V A;  3VJE A;  2I19 A;  3N5J F;  3NPR A;  1N24 A;  3V1X A;  5CG6 A;  3KRA A;  2AEK A;  3OYR A;  2E8U A;  2OA6 A;  1DGP A;  1N21 A;  3KRP A;  4OMG A;  2E92 A;  2PS4 A;  3WEI A;  4HD1 A;  2J1P A;  4UMJ A;  3WC9 A;  2E8V A;  5IMN A;  3WCG A;  3WEK A;  2FOR A;  5B01 A;  3DYH A;  1YHL A;  4KFA A;  3DYF A;  2E95 A;  2E91 A;  3WCB A;  3N0F A;  1VG4 A;  3WJK A;  3WCA A;  2E4O A;  4NFJ F;  5DW7 A;  3AQC B;  2F8Z F;  1YJ4 A;  3G4F A;  1WKZ A;  3KRF B;  5AHU B; 
#chains in the Genus database with same CATH homology
 5IKA A;  4E9U A;  1V4H A;  4Q23 A;  5A0J A;  3N0G A;  3WCD A;  3WEJ A;  1HXA A;  4JXN A;  5AFX A;  3P5P A;  3OAC B;  4KVY A;  1VG2 A;  4LUU A;  4LZ3 A;  2Z78 A;  5ERN A;  3LMD A;  5DGS F;  5IVG A;  1PS1 A;  4KUX A;  3ZMB A;  2OPN A;  5EAS A;  5HN8 A;  3VJA A;  1V4I A;  3VJC A;  3MAV A;  4L2X F;  4FP4 A;  3OAB A;  3M9U A;  4DXJ A;  5ILK A;  2J5C A;  3S4J A;  3LVS A;  5DIQ F;  4P0X A;  2E8X A;  5ERO A;  3WSB A;  5IKH A;  4FJQ A;  3ID0 A;  5IMP A;  2E90 A;  4OKM A;  3Q2Q A;  4LZ0 A;  5JUZ F;  2VF6 A;  3VJ8 A;  4KKM A;  1VG6 A;  5IL3 A;  4EA1 A;  3WEG A;  2P1C A;  3M01 A;  2ZEU A;  1WL1 A;  4EA0 A;  2PS7 A;  1JFG A;  3EFQ A;  1VG3 A;  4NKE A;  2Z4V A;  3LZ9 A;  4PVX F;  4LPG F;  4N1Z F;  4OKZ A;  4N9U A;  4KPD A;  4P0W A;  3G4D A;  1YYS A;  5IK0 A;  4GAX A;  4KWD A;  5ILZ A;  3ICN A;  3ICM A;  4XQR F;  3B7L A;  4H5C F;  4MC3 A;  5B02 A;  3ICK A;  2E94 A;  3WEF A;  2E8T A;  4XQT F;  3WCC A;  4KQ5 A;  1JFA A;  5IM1 A;  4QPF A;  5B03 A;  2ONH A;  3Q2Z A;  3M00 A;  3LLW A;  3ASX A;  3NF2 A;  5JV0 F;  4K10 A;  5B0L A;  3N46 F;  2AZK A;  3ZMC A;  1KIZ A;  3CP6 A;  3EGT A;  3M02 A;  1RQI A;  3LEE A;  5B00 A;  4GP1 A;  2ZEV A;  4LOB A;  5EAU A;  4DWG A;  3OAB B;  4LA5 A;  1YYR A;  5ILJ A;  3KRC A;  3N6K F;  1EZF A;  2Z7H A;  4NFI F;  5IK9 A;  4LLT A;  3P41 A;  3VJ9 A;  3RMG A;  3Q30 A;  3ZL6 A;  4E9Z A;  2OPM A;  1HXG A;  2PS5 A;  3RYW A;  5ILI A;  3PKO A;  5CG5 A;  3SDR A;  3WCE A;  4RNQ A;  3ACX A;  2FTZ A;  4MC8 A;  2E93 A;  2ZCQ A;  2ZY1 A;  1V4J A;  1HM4 A;  5DHK A;  3RBM A;  3TFV A;  5E8H A;  3WJO A;  4KQS A;  1V4E A;  4KVW A;  2Z52 A;  3NPK A;  3WCJ A;  3V1V A;  3AQ0 A;  1V4K A;  4F6V A;  4LTZ A;  3CC9 A;  3KRO A;  2ONG A;  1HX9 A;  2Z50 A;  4LFE A;  1UBX A;  2F7M F;  3KBK A;  5IK6 A;  1KIY A;  1YHK A;  4NKF A;  3WCI A;  3P8R A;  4JZX A;  5HN9 A;  3TS7 A;  2EWG A;  3N3L F;  4DEM F;  4LPH F;  3LGZ B;  2F89 F;  3KRA B;  1WMW A;  2RAH A;  3N1W F;  4JYX A;  4KVD A;  2ZCS A;  4RXE A;  3KRP B;  1YHM A;  3PYB A;  3DYG A;  5H9D A;  3PH7 A;  4LFG A;  4MC0 A;  2Z7I A;  4DWB A;  1UBW A;  4LZC A;  3LG5 A;  4LIX A;  3VJB A;  3QQV A;  3IPI A;  3KRF A;  3SDV A;  3BNX A;  1N22 A;  5ILD A;  4PVY F;  3KB9 A;  4OMH A;  4OGU A;  3PDE A;  2F9K F;  5B0M A;  2E8W A;  5C05 A;  2AEL A;  3KRC B;  4F62 A;  4DHD A;  4LXW A;  4EA2 A;  5E8L A;  3CKE A;  3ADZ A;  2F94 F;  4JVJ F;  5EAT A;  2DH4 A;  3VJD A;  2Z4W A;  1FPS A;  3AQB B;  1ZW5 A;  4GA3 A;  4KK2 A;  2Z4X A;  2Q9Y A;  5ERM A;  1N1Z A;  2F8C F;  4KVI A;  5JV1 F;  1N20 A;  3KRO B;  3IBA A;  4LA6 A;  3W7F A;  2F92 F;  2J1O A;  2AZJ A;  3V66 A;  2ZCO A;  3ICZ A;  2Z4Z A;  3P5R A;  3WJN A;  5A0I A;  2Q58 A;  5ILH A;  5JA0 F;  1YQ7 A;  3M0G A;  4LLS A;  1HM7 A;  3N3D A;  3MZV A;  3SAE A;  1WY0 A;  1YYU A;  3BNY A;  5IL8 A;  5DGN F;  3ACY A;  3QKC A;  3SDQ A;  5A0K A;  1WL2 A;  4WK5 A;  1WL0 A;  3APZ A;  1YYQ A;  5HN7 A;  4NFK F;  1YYT A;  1N1B A;  3ZCD A;  5DHI A;  5I1U A;  5AEL A;  3WE9 A;  3WCH A;  2ZCR A;  5AYP A;  1UBY A;  3UCA A;  1HXC A;  3LOM A;  4LTV A;  5B0J A;  3RYE A;  2Q80 A;  4F6X A;  4DI5 A;  3TFP A;  2O1O A;  2QIS A;  5B0K A;  5DJP F;  4RXC A;  2AET A;  3ACW A;  4LFV F;  4XQS F;  3WEH A;  4JXY A;  5IMI A;  3NRI A;  3SDT A;  1RQJ A;  4E1E A;  3N49 F;  4JZB A;  4NG6 A;  3TFN A;  3N45 F;  5JV2 F;  2H8O A;  5ILY A;  3ZOU A;  3N5H F;  4RXA A;  4KQU A;  4KPJ A;  2Z4Y A;  4NUA A;  4ZQ8 A;  3WCM A;  1N23 A;  5ER8 A;  5DZ2 A;  1WL3 A;  5KSX F;  1DI1 A;  5DJV F;  3LDW A;  3LSN A;  3LGK A;  2OGD A;  3S9V A;  3N1V F;  5HNA A;  3TC1 A;  3PYA A;  2PS6 A;  4GP2 A;  5DGM F;  1YV5 A;  4QXS F;  5B0I A;  3OAC A;  4H5E F;  3AE0 A;  5IN8 A;  1UBV A;  3EZ3 A;  2Q9Z A;  4H5D F;  3WSA A;  3LK5 A;  2AZL A;  4DZW A;  4RYP A;  4RXD A;  2PS8 A;  5E8K A;  3WCF A;  5DJR F;  1VG7 A;  3WCL A;  3P8L A;  1RTR A;  3LJI A;  3Q1O A;  3SDU A;  4P0V A;  3VJE A;  2I19 A;  3N5J F;  3NPR A;  1N24 A;  3V1X A;  5CG6 A;  3KRA A;  2AEK A;  3OYR A;  2E8U A;  2OA6 A;  1DGP A;  1N21 A;  3KRP A;  4OMG A;  2E92 A;  2PS4 A;  3WEI A;  4HD1 A;  2J1P A;  4UMJ A;  3WC9 A;  2E8V A;  5IMN A;  3WCG A;  3WEK A;  2FOR A;  5B01 A;  3DYH A;  1YHL A;  4KFA A;  3DYF A;  2E95 A;  2E91 A;  3WCB A;  3N0F A;  1VG4 A;  3WJK A;  3WCA A;  2E4O A;  4NFJ F;  5DW7 A;  3AQC B;  2F8Z F;  1YJ4 A;  3G4F A;  1WKZ A;  3KRF B;  5AHU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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