4DWBA

Crystal structure of trypanosoma cruzi farnesyl diphosphate synthase in complex with [2-(n-pentylamino)ethane-1,1-diyl]bisphosphonic acid and mg2+
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
361
structure length
361
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 146
structure length 361
sequence length 361
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2012-02-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4dwbA00
2AETA 3MZVA 3TC1A 1ZW5A 3WEKA 3WEFA 2Q80A 3ICZA 4LFEA 2J1PA 3W7FA 5B0LA 5E8LA 4P0XA 3WCBA 4XQRF 2Z4VA 1HM4A 4GP2A 4KQUA 2F8ZF 3BNYA 2AZKA 3N5HF 5JV1F 5B02A 3DYFA 5HNAA 2ZY1A 3G4FA 4JYXA 3CKEA 1YYRA 1N24A 3WEHA 3V1XA 2DH4A 5ILJA 3WCAA 2ZEUA 2E8TA 1N1ZA 1YYTA 2PS7A 3LDWA 5DHKA 2Q9YA 2ONHA 2PS6A 3AQ0A 1V4EA 1UBWA 5IK6A 4OMHA 5A0KA 3ACYA 3LK5A 4NKFA 5EROA 2FTZA 4L2XF 3PYAA 1N22A 3V1VA 4LLTA 4UMJA 3VJDA 3N46F 3AQBB 3Q2ZA 4JZXA 1EZFA 3N1VF 1WL1A 4QXSF 3WSBA 3WCCA 1V4IA 3LOMA 4NG6A 1YHKA 4NUAA 4KVDA 2E92A 1YYSA 5AFXA 3Q30A 4H5DF 3S4JA 4DZWA 3ACXA 2ZCRA 5B0KA 3CC9A 4LA6A 5CG5A 3UCAA 4ZQ8A 2J1OA 5ILZA 4H5CF 3PDEA 3G4DA 3PH7A 2O1OA 3DYHA 1JFGA 3M9UA 3N5JF 5AYPA 2OA6A 2AZJA 2E8WA 2FORA 3P5RA 1N1BA 4XQSF 3KBKA 2E8VA 3KRPA 5A0JA 5AELA 3ACWA 4XQTF 5B0MA 1VG6A 4N1ZF 4LUUA 4F62A 3LGKA 2E91A 3WCJA 3N0FA 3N49F 1UBYA 5EATA 4LPHF 3QKCA 5HN7A 2Z7HA 3ZCDA 4MC3A 3ICKA 1DGPA 1RQIA 3NPKA 3SDTA 2F89F 1N20A 2Z4XA 3M01A 1V4JA 2E94A 4PVYF 5A0IA 4LOBA 5B0JA 3N3DA 4RXCA 2P1CA 5JV2F 5DZ2A 3M02A 3KRPB 3NPRA 5B01A 4RNQA 1YQ7A 3ZMCA 2Z52A 3EZ3A 3TS7A 3KRFA 2PS5A 5ILDA 2E95A 5IMIA 2I19A 2E90A 3ASXA 3KRCB 4LFVF 4KUXA 2E8XA 4GP1A 3RYEA 2AEKA 1HXCA 2AZLA 4H5EF 4WK5A 1KIYA 3N3LF 4LZ0A 4JZBA 4LIXA 4KKMA 3LGZB 3P41A 3RYWA 3WE9A 4DI5A 5DGMF 5EASA 3SAEA 3TFNA 3WCFA 3Q2QA 5IM1A 3OACB 2AELA 3KROA 5H9DA 1DI1A 3WJOA 4MC0A 3RMGA 5ERNA 5B0IA 1UBXA 5CG6A 3N1WF 1YHMA 3KRFB 3WJNA 4KQSA 4EA2A 1RQJA 4MC8A 3PYBA 5C05A 3N0GA 3MAVA 4GA3A 2ZEVA 5E8HA 2E93A 3ICNA 4OMGA 3LLWA 3KB9A 4KPDA 2ZCOA 4NKEA 5DGSF 3ADZA 3LZ9A 1UBVA 3NRIA 3BNXA 1KIZA 3WEGA 3Q1OA 3P8LA 5IKHA 4K10A 3M0GA 2J5CA 5IMNA 3DYGA 4E9ZA 4F6VA 2OPNA 3ICMA 3M00A 3KROB 4DXJA 3VJEA 3IBAA 3IPIA 2Z4YA 1V4KA 5IKAA 2E8UA 4P0WA 2F9KF 5DGNF 3WCDA 1PS1A 1WL3A 4QPFA 5JV0F 3SDVA 1VG3A 2ZCSA 2Z7IA 4N9UA 1HXGA 5ERMA 5DIQF 3KRCA 2PS8A 4LXWA 2H8OA 3PKOA 5IMPA 3APZA 5KSXF 4LA5A 2F8CF 3LJIA 4JXNA 3WCGA 4OKMA 5JUZF 3WEIA 3ZMBA 3WCMA 4NFIF 3P8RA 3AQCB 4PVXF 3LG5A 5IL3A 1VG7A 3OACA 3LMDA 3KRAB 2Q58A 3SDRA 2Z78A 4F6XA 1V4HA 4KVWA 3WSAA 5IK9A 3WCHA 1WMWA 3S9VA 3VJCA 1YYQA 5DW7A 4LTZA 1WL0A 1VG2A 5ILKA 5HN8A 4JXYA 3AE0A 5AHUB 3WCIA 3WC9A 2F92F 4KWDA 4EA1A 4RXAA 2ONGA 2ZCQA 3OABA 3WJKA 4RXEA 3LEEA 3WCEA 1WKZA 4GAXA 1WL2A 5IL8A 5ER8A 5DJPF 5I1UA 5B03A 4NFJF 4RXDA 1HM7A 5DHIA 1VG4A 4DHDA 5ILYA 3CP6A 4KK2A 2E4OA 4E1EA 1FPSA 3OYRA 4LZ3A 1JFAA 2F7MF 3VJ9A 5E8KA 4EA0A 1HXAA 5IVGA 2VF6A 2F94F 5JA0F 3VJBA 4DEMF 1YYUA 5IK0A 3OABB 3N45F 4LZCA 1N23A 3ZL6A 4NFKF 4RYPA 2Z50A 4KVYA 4FJQA 1YHLA 3B7LA 2Q9ZA 1YJ4A 2EWGA 4KPJA 4OKZA 4LTVA 3KRAA 3RBMA 5B00A 2Z4ZA 3ID0A 3EGTA 4LFGA 3SDUA 2QISA 1YV5A 1WY0A 3N6KF 5ILIA 3LSNA 4DWGA 5IN8A 4P0VA 5HN9A 3TFPA 3VJ8A 4KFAA 4FP4A 3EFQA 3WEJA 5ILHA 3NF2A 4E9UA 2OGDA 3VJAA 4LLSA 3TFVA 2Z4WA 2OPMA 4JVJF 3QQVA 1N21A 4Q23A 5DJRF 3P5PA 2PS4A 1RTRA 4KVIA 4LPGF 4HD1A 3V66A 3SDQA 4KQ5A 5DJVF 5EAUA 3ZOUA 1HX9A 4OGUA 3LVSA 4DWBA 2RAHA 3WCLA
chains in the Genus database with same CATH superfamily
2AETA 3MZVA 3TC1A 1ZW5A 3WEKA 3WEFA 2Q80A 3ICZA 4LFEA 2J1PA 3W7FA 5B0LA 5E8LA 4P0XA 3WCBA 4XQRF 2Z4VA 1HM4A 4GP2A 4KQUA 2F8ZF 3BNYA 2AZKA 3N5HF 5JV1F 5B02A 3DYFA 5HNAA 2ZY1A 3G4FA 4JYXA 3CKEA 1YYRA 1N24A 3WEHA 3V1XA 2DH4A 5ILJA 3WCAA 2ZEUA 2E8TA 1N1ZA 1YYTA 2PS7A 3LDWA 5DHKA 2Q9YA 2ONHA 2PS6A 3AQ0A 1V4EA 1UBWA 5IK6A 4OMHA 5A0KA 3ACYA 3LK5A 4NKFA 5EROA 2FTZA 4L2XF 3PYAA 1N22A 3V1VA 4LLTA 4UMJA 3VJDA 3N46F 3AQBB 3Q2ZA 4JZXA 1EZFA 3N1VF 1WL1A 4QXSF 3WSBA 3WCCA 1V4IA 3LOMA 4NG6A 1YHKA 4NUAA 4KVDA 2E92A 1YYSA 5AFXA 3Q30A 4H5DF 3S4JA 4DZWA 3ACXA 2ZCRA 5B0KA 3CC9A 4LA6A 5CG5A 3UCAA 4ZQ8A 2J1OA 5ILZA 4H5CF 3PDEA 3G4DA 3PH7A 2O1OA 3DYHA 1JFGA 3M9UA 3N5JF 5AYPA 2OA6A 2AZJA 2E8WA 2FORA 3P5RA 1N1BA 4XQSF 3KBKA 2E8VA 3KRPA 5A0JA 5AELA 3ACWA 4XQTF 5B0MA 1VG6A 4N1ZF 4LUUA 4F62A 3LGKA 2E91A 3WCJA 3N0FA 3N49F 1UBYA 5EATA 4LPHF 3QKCA 5HN7A 2Z7HA 3ZCDA 4MC3A 3ICKA 1DGPA 1RQIA 3NPKA 3SDTA 2F89F 1N20A 2Z4XA 3M01A 1V4JA 2E94A 4PVYF 5A0IA 4LOBA 5B0JA 3N3DA 4RXCA 2P1CA 5JV2F 5DZ2A 3M02A 3KRPB 3NPRA 5B01A 4RNQA 1YQ7A 3ZMCA 2Z52A 3EZ3A 3TS7A 3KRFA 2PS5A 5ILDA 2E95A 5IMIA 2I19A 2E90A 3ASXA 3KRCB 4LFVF 4KUXA 2E8XA 4GP1A 3RYEA 2AEKA 1HXCA 2AZLA 4H5EF 4WK5A 1KIYA 3N3LF 4LZ0A 4JZBA 4LIXA 4KKMA 3LGZB 3P41A 3RYWA 3WE9A 4DI5A 5DGMF 5EASA 3SAEA 3TFNA 3WCFA 3Q2QA 5IM1A 3OACB 2AELA 3KROA 5H9DA 1DI1A 3WJOA 4MC0A 3RMGA 5ERNA 5B0IA 1UBXA 5CG6A 3N1WF 1YHMA 3KRFB 3WJNA 4KQSA 4EA2A 1RQJA 4MC8A 3PYBA 5C05A 3N0GA 3MAVA 4GA3A 2ZEVA 5E8HA 2E93A 3ICNA 4OMGA 3LLWA 3KB9A 4KPDA 2ZCOA 4NKEA 5DGSF 3ADZA 3LZ9A 1UBVA 3NRIA 3BNXA 1KIZA 3WEGA 3Q1OA 3P8LA 5IKHA 4K10A 3M0GA 2J5CA 5IMNA 3DYGA 4E9ZA 4F6VA 2OPNA 3ICMA 3M00A 3KROB 4DXJA 3VJEA 3IBAA 3IPIA 2Z4YA 1V4KA 5IKAA 2E8UA 4P0WA 2F9KF 5DGNF 3WCDA 1PS1A 1WL3A 4QPFA 5JV0F 3SDVA 1VG3A 2ZCSA 2Z7IA 4N9UA 1HXGA 5ERMA 5DIQF 3KRCA 2PS8A 4LXWA 2H8OA 3PKOA 5IMPA 3APZA 5KSXF 4LA5A 2F8CF 3LJIA 4JXNA 3WCGA 4OKMA 5JUZF 3WEIA 3ZMBA 3WCMA 4NFIF 3P8RA 3AQCB 4PVXF 3LG5A 5IL3A 1VG7A 3OACA 3LMDA 3KRAB 2Q58A 3SDRA 2Z78A 4F6XA 1V4HA 4KVWA 3WSAA 5IK9A 3WCHA 1WMWA 3S9VA 3VJCA 1YYQA 5DW7A 4LTZA 1WL0A 1VG2A 5ILKA 5HN8A 4JXYA 3AE0A 5AHUB 3WCIA 3WC9A 2F92F 4KWDA 4EA1A 4RXAA 2ONGA 2ZCQA 3OABA 3WJKA 4RXEA 3LEEA 3WCEA 1WKZA 4GAXA 1WL2A 5IL8A 5ER8A 5DJPF 5I1UA 5B03A 4NFJF 4RXDA 1HM7A 5DHIA 1VG4A 4DHDA 5ILYA 3CP6A 4KK2A 2E4OA 4E1EA 1FPSA 3OYRA 4LZ3A 1JFAA 2F7MF 3VJ9A 5E8KA 4EA0A 1HXAA 5IVGA 2VF6A 2F94F 5JA0F 3VJBA 4DEMF 1YYUA 5IK0A 3OABB 3N45F 4LZCA 1N23A 3ZL6A 4NFKF 4RYPA 2Z50A 4KVYA 4FJQA 1YHLA 3B7LA 2Q9ZA 1YJ4A 2EWGA 4KPJA 4OKZA 4LTVA 3KRAA 3RBMA 5B00A 2Z4ZA 3ID0A 3EGTA 4LFGA 3SDUA 2QISA 1YV5A 1WY0A 3N6KF 5ILIA 3LSNA 4DWGA 5IN8A 4P0VA 5HN9A 3TFPA 3VJ8A 4KFAA 4FP4A 3EFQA 3WEJA 5ILHA 3NF2A 4E9UA 2OGDA 3VJAA 4LLSA 3TFVA 2Z4WA 2OPMA 4JVJF 3QQVA 1N21A 4Q23A 5DJRF 3P5PA 2PS4A 1RTRA 4KVIA 4LPGF 4HD1A 3V66A 3SDQA 4KQ5A 5DJVF 5EAUA 3ZOUA 1HX9A 4OGUA 3LVSA 4DWBA 2RAHA 3WCLA
chains in the Genus database with same CATH topology
2AETA 3MZVA 3TC1A 1ZW5A 3WEKA 3WEFA 2Q80A 3ICZA 4LFEA 2J1PA 3W7FA 5B0LA 5E8LA 4P0XA 3WCBA 4XQRF 2Z4VA 1HM4A 4GP2A 4KQUA 2F8ZF 3BNYA 2AZKA 3N5HF 5JV1F 5B02A 3DYFA 5HNAA 2ZY1A 3G4FA 4JYXA 3CKEA 1YYRA 1N24A 3WEHA 3V1XA 2DH4A 5ILJA 3WCAA 2ZEUA 2E8TA 1N1ZA 1YYTA 2PS7A 3LDWA 5DHKA 2Q9YA 2ONHA 2PS6A 3AQ0A 1V4EA 1UBWA 5IK6A 4OMHA 5A0KA 3ACYA 3LK5A 4NKFA 5EROA 2FTZA 4L2XF 3PYAA 1N22A 3V1VA 4LLTA 4UMJA 3VJDA 3N46F 3AQBB 3Q2ZA 4JZXA 1EZFA 3N1VF 1WL1A 4QXSF 3WSBA 3WCCA 1V4IA 3LOMA 4NG6A 1YHKA 4NUAA 4KVDA 2E92A 1YYSA 5AFXA 3Q30A 4H5DF 3S4JA 4DZWA 3ACXA 2ZCRA 5B0KA 3CC9A 4LA6A 5CG5A 3UCAA 4ZQ8A 2J1OA 5ILZA 4H5CF 3PDEA 3G4DA 3PH7A 2O1OA 3DYHA 1JFGA 3M9UA 3N5JF 5AYPA 2OA6A 2AZJA 2E8WA 2FORA 3P5RA 1N1BA 4XQSF 3KBKA 2E8VA 3KRPA 5A0JA 5AELA 3ACWA 4XQTF 5B0MA 1VG6A 4N1ZF 4LUUA 4F62A 3LGKA 2E91A 3WCJA 3N0FA 3N49F 1UBYA 5EATA 4LPHF 3QKCA 5HN7A 2Z7HA 3ZCDA 4MC3A 3ICKA 1DGPA 1RQIA 3NPKA 3SDTA 2F89F 1N20A 2Z4XA 3M01A 1V4JA 2E94A 4PVYF 5A0IA 4LOBA 5B0JA 3N3DA 4RXCA 2P1CA 5JV2F 5DZ2A 3M02A 3KRPB 3NPRA 5B01A 4RNQA 1YQ7A 3ZMCA 2Z52A 3EZ3A 3TS7A 3KRFA 2PS5A 5ILDA 2E95A 5IMIA 2I19A 2E90A 3ASXA 3KRCB 4LFVF 4KUXA 2E8XA 4GP1A 3RYEA 2AEKA 1HXCA 2AZLA 4H5EF 4WK5A 1KIYA 3N3LF 4LZ0A 4JZBA 4LIXA 4KKMA 3LGZB 3P41A 3RYWA 3WE9A 4DI5A 5DGMF 5EASA 3SAEA 3TFNA 3WCFA 3Q2QA 5IM1A 3OACB 2AELA 3KROA 5H9DA 1DI1A 3WJOA 4MC0A 3RMGA 5ERNA 5B0IA 1UBXA 5CG6A 3N1WF 1YHMA 3KRFB 3WJNA 4KQSA 4EA2A 1RQJA 4MC8A 3PYBA 5C05A 3N0GA 3MAVA 4GA3A 2ZEVA 5E8HA 2E93A 3ICNA 4OMGA 3LLWA 3KB9A 4KPDA 2ZCOA 4NKEA 5DGSF 3ADZA 3LZ9A 1UBVA 3NRIA 3BNXA 1KIZA 3WEGA 3Q1OA 3P8LA 5IKHA 4K10A 3M0GA 2J5CA 5IMNA 3DYGA 4E9ZA 4F6VA 2OPNA 3ICMA 3M00A 3KROB 4DXJA 3VJEA 3IBAA 3IPIA 2Z4YA 1V4KA 5IKAA 2E8UA 4P0WA 2F9KF 5DGNF 3WCDA 1PS1A 1WL3A 4QPFA 5JV0F 3SDVA 1VG3A 2ZCSA 2Z7IA 4N9UA 1HXGA 5ERMA 5DIQF 3KRCA 2PS8A 4LXWA 2H8OA 3PKOA 5IMPA 3APZA 5KSXF 4LA5A 2F8CF 3LJIA 4JXNA 3WCGA 4OKMA 5JUZF 3WEIA 3ZMBA 3WCMA 4NFIF 3P8RA 3AQCB 4PVXF 3LG5A 5IL3A 1VG7A 3OACA 3LMDA 3KRAB 2Q58A 3SDRA 2Z78A 4F6XA 1V4HA 4KVWA 3WSAA 5IK9A 3WCHA 1WMWA 3S9VA 3VJCA 1YYQA 5DW7A 4LTZA 1WL0A 1VG2A 5ILKA 5HN8A 4JXYA 3AE0A 5AHUB 3WCIA 3WC9A 2F92F 4KWDA 4EA1A 4RXAA 2ONGA 2ZCQA 3OABA 3WJKA 4RXEA 3LEEA 3WCEA 1WKZA 4GAXA 1WL2A 5IL8A 5ER8A 5DJPF 5I1UA 5B03A 4NFJF 4RXDA 1HM7A 5DHIA 1VG4A 4DHDA 5ILYA 3CP6A 4KK2A 2E4OA 4E1EA 1FPSA 3OYRA 4LZ3A 1JFAA 2F7MF 3VJ9A 5E8KA 4EA0A 1HXAA 5IVGA 2VF6A 2F94F 5JA0F 3VJBA 4DEMF 1YYUA 5IK0A 3OABB 3N45F 4LZCA 1N23A 3ZL6A 4NFKF 4RYPA 2Z50A 4KVYA 4FJQA 1YHLA 3B7LA 2Q9ZA 1YJ4A 2EWGA 4KPJA 4OKZA 4LTVA 3KRAA 3RBMA 5B00A 2Z4ZA 3ID0A 3EGTA 4LFGA 3SDUA 2QISA 1YV5A 1WY0A 3N6KF 5ILIA 3LSNA 4DWGA 5IN8A 4P0VA 5HN9A 3TFPA 3VJ8A 4KFAA 4FP4A 3EFQA 3WEJA 5ILHA 3NF2A 4E9UA 2OGDA 3VJAA 4LLSA 3TFVA 2Z4WA 2OPMA 4JVJF 3QQVA 1N21A 4Q23A 5DJRF 3P5PA 2PS4A 1RTRA 4KVIA 4LPGF 4HD1A 3V66A 3SDQA 4KQ5A 5DJVF 5EAUA 3ZOUA 1HX9A 4OGUA 3LVSA 4DWBA 2RAHA 3WCLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AET A;  3MZV A;  3TC1 A;  1ZW5 A;  3WEK A;  3WEF A;  2Q80 A;  3ICZ A;  4LFE A;  2J1P A;  3W7F A;  5B0L A;  5E8L A;  4P0X A;  3WCB A;  4XQR F;  2Z4V A;  1HM4 A;  4GP2 A;  4KQU A;  2F8Z F;  3BNY A;  2AZK A;  3N5H F;  5JV1 F;  5B02 A;  3DYF A;  5HNA A;  2ZY1 A;  3G4F A;  4JYX A;  3CKE A;  1YYR A;  1N24 A;  3WEH A;  3V1X A;  2DH4 A;  5ILJ A;  3WCA A;  2ZEU A;  2E8T A;  1N1Z A;  1YYT A;  2PS7 A;  3LDW A;  5DHK A;  2Q9Y A;  2ONH A;  2PS6 A;  3AQ0 A;  1V4E A;  1UBW A;  5IK6 A;  4OMH A;  5A0K A;  3ACY A;  3LK5 A;  4NKF A;  5ERO A;  2FTZ A;  4L2X F;  3PYA A;  1N22 A;  3V1V A;  4LLT A;  4UMJ A;  3VJD A;  3N46 F;  3AQB B;  3Q2Z A;  4JZX A;  1EZF A;  3N1V F;  1WL1 A;  4QXS F;  3WSB A;  3WCC A;  1V4I A;  3LOM A;  4NG6 A;  1YHK A;  4NUA A;  4KVD A;  2E92 A;  1YYS A;  5AFX A;  3Q30 A;  4H5D F;  3S4J A;  4DZW A;  3ACX A;  2ZCR A;  5B0K A;  3CC9 A;  4LA6 A;  5CG5 A;  3UCA A;  4ZQ8 A;  2J1O A;  5ILZ A;  4H5C F;  3PDE A;  3G4D A;  3PH7 A;  2O1O A;  3DYH A;  1JFG A;  3M9U A;  3N5J F;  5AYP A;  2OA6 A;  2AZJ A;  2E8W A;  2FOR A;  3P5R A;  1N1B A;  4XQS F;  3KBK A;  2E8V A;  3KRP A;  5A0J A;  5AEL A;  3ACW A;  4XQT F;  5B0M A;  1VG6 A;  4N1Z F;  4LUU A;  4F62 A;  3LGK A;  2E91 A;  3WCJ A;  3N0F A;  3N49 F;  1UBY A;  5EAT A;  4LPH F;  3QKC A;  5HN7 A;  2Z7H A;  3ZCD A;  4MC3 A;  3ICK A;  1DGP A;  1RQI A;  3NPK A;  3SDT A;  2F89 F;  1N20 A;  2Z4X A;  3M01 A;  1V4J A;  2E94 A;  4PVY F;  5A0I A;  4LOB A;  5B0J A;  3N3D A;  4RXC A;  2P1C A;  5JV2 F;  5DZ2 A;  3M02 A;  3KRP B;  3NPR A;  5B01 A;  4RNQ A;  1YQ7 A;  3ZMC A;  2Z52 A;  3EZ3 A;  3TS7 A;  3KRF A;  2PS5 A;  5ILD A;  2E95 A;  5IMI A;  2I19 A;  2E90 A;  3ASX A;  3KRC B;  4LFV F;  4KUX A;  2E8X A;  4GP1 A;  3RYE A;  2AEK A;  1HXC A;  2AZL A;  4H5E F;  4WK5 A;  1KIY A;  3N3L F;  4LZ0 A;  4JZB A;  4LIX A;  4KKM A;  3LGZ B;  3P41 A;  3RYW A;  3WE9 A;  4DI5 A;  5DGM F;  5EAS A;  3SAE A;  3TFN A;  3WCF A;  3Q2Q A;  5IM1 A;  3OAC B;  2AEL A;  3KRO A;  5H9D A;  1DI1 A;  3WJO A;  4MC0 A;  3RMG A;  5ERN A;  5B0I A;  1UBX A;  5CG6 A;  3N1W F;  1YHM A;  3KRF B;  3WJN A;  4KQS A;  4EA2 A;  1RQJ A;  4MC8 A;  3PYB A;  5C05 A;  3N0G A;  3MAV A;  4GA3 A;  2ZEV A;  5E8H A;  2E93 A;  3ICN A;  4OMG A;  3LLW A;  3KB9 A;  4KPD A;  2ZCO A;  4NKE A;  5DGS F;  3ADZ A;  3LZ9 A;  1UBV A;  3NRI A;  3BNX A;  1KIZ A;  3WEG A;  3Q1O A;  3P8L A;  5IKH A;  4K10 A;  3M0G A;  2J5C A;  5IMN A;  3DYG A;  4E9Z A;  4F6V A;  2OPN A;  3ICM A;  3M00 A;  3KRO B;  4DXJ A;  3VJE A;  3IBA A;  3IPI A;  2Z4Y A;  1V4K A;  5IKA A;  2E8U A;  4P0W A;  2F9K F;  5DGN F;  3WCD A;  1PS1 A;  1WL3 A;  4QPF A;  5JV0 F;  3SDV A;  1VG3 A;  2ZCS A;  2Z7I A;  4N9U A;  1HXG A;  5ERM A;  5DIQ F;  3KRC A;  2PS8 A;  4LXW A;  2H8O A;  3PKO A;  5IMP A;  3APZ A;  5KSX F;  4LA5 A;  2F8C F;  3LJI A;  4JXN A;  3WCG A;  4OKM A;  5JUZ F;  3WEI A;  3ZMB A;  3WCM A;  4NFI F;  3P8R A;  3AQC B;  4PVX F;  3LG5 A;  5IL3 A;  1VG7 A;  3OAC A;  3LMD A;  3KRA B;  2Q58 A;  3SDR A;  2Z78 A;  4F6X A;  1V4H A;  4KVW A;  3WSA A;  5IK9 A;  3WCH A;  1WMW A;  3S9V A;  3VJC A;  1YYQ A;  5DW7 A;  4LTZ A;  1WL0 A;  1VG2 A;  5ILK A;  5HN8 A;  4JXY A;  3AE0 A;  5AHU B;  3WCI A;  3WC9 A;  2F92 F;  4KWD A;  4EA1 A;  4RXA A;  2ONG A;  2ZCQ A;  3OAB A;  3WJK A;  4RXE A;  3LEE A;  3WCE A;  1WKZ A;  4GAX A;  1WL2 A;  5IL8 A;  5ER8 A;  5DJP F;  5I1U A;  5B03 A;  4NFJ F;  4RXD A;  1HM7 A;  5DHI A;  1VG4 A;  4DHD A;  5ILY A;  3CP6 A;  4KK2 A;  2E4O A;  4E1E A;  1FPS A;  3OYR A;  4LZ3 A;  1JFA A;  2F7M F;  3VJ9 A;  5E8K A;  4EA0 A;  1HXA A;  5IVG A;  2VF6 A;  2F94 F;  5JA0 F;  3VJB A;  4DEM F;  1YYU A;  5IK0 A;  3OAB B;  3N45 F;  4LZC A;  1N23 A;  3ZL6 A;  4NFK F;  4RYP A;  2Z50 A;  4KVY A;  4FJQ A;  1YHL A;  3B7L A;  2Q9Z A;  1YJ4 A;  2EWG A;  4KPJ A;  4OKZ A;  4LTV A;  3KRA A;  3RBM A;  5B00 A;  2Z4Z A;  3ID0 A;  3EGT A;  4LFG A;  3SDU A;  2QIS A;  1YV5 A;  1WY0 A;  3N6K F;  5ILI A;  3LSN A;  4DWG A;  5IN8 A;  4P0V A;  5HN9 A;  3TFP A;  3VJ8 A;  4KFA A;  4FP4 A;  3EFQ A;  3WEJ A;  5ILH A;  3NF2 A;  4E9U A;  2OGD A;  3VJA A;  4LLS A;  3TFV A;  2Z4W A;  2OPM A;  4JVJ F;  3QQV A;  1N21 A;  4Q23 A;  5DJR F;  3P5P A;  2PS4 A;  1RTR A;  4KVI A;  4LPG F;  4HD1 A;  3V66 A;  3SDQ A;  4KQ5 A;  5DJV F;  5EAU A;  3ZOU A;  1HX9 A;  4OGU A;  3LVS A;  4DWB A;  2RAH A;  3WCL A; 
#chains in the Genus database with same CATH topology
 2AET A;  3MZV A;  3TC1 A;  1ZW5 A;  3WEK A;  3WEF A;  2Q80 A;  3ICZ A;  4LFE A;  2J1P A;  3W7F A;  5B0L A;  5E8L A;  4P0X A;  3WCB A;  4XQR F;  2Z4V A;  1HM4 A;  4GP2 A;  4KQU A;  2F8Z F;  3BNY A;  2AZK A;  3N5H F;  5JV1 F;  5B02 A;  3DYF A;  5HNA A;  2ZY1 A;  3G4F A;  4JYX A;  3CKE A;  1YYR A;  1N24 A;  3WEH A;  3V1X A;  2DH4 A;  5ILJ A;  3WCA A;  2ZEU A;  2E8T A;  1N1Z A;  1YYT A;  2PS7 A;  3LDW A;  5DHK A;  2Q9Y A;  2ONH A;  2PS6 A;  3AQ0 A;  1V4E A;  1UBW A;  5IK6 A;  4OMH A;  5A0K A;  3ACY A;  3LK5 A;  4NKF A;  5ERO A;  2FTZ A;  4L2X F;  3PYA A;  1N22 A;  3V1V A;  4LLT A;  4UMJ A;  3VJD A;  3N46 F;  3AQB B;  3Q2Z A;  4JZX A;  1EZF A;  3N1V F;  1WL1 A;  4QXS F;  3WSB A;  3WCC A;  1V4I A;  3LOM A;  4NG6 A;  1YHK A;  4NUA A;  4KVD A;  2E92 A;  1YYS A;  5AFX A;  3Q30 A;  4H5D F;  3S4J A;  4DZW A;  3ACX A;  2ZCR A;  5B0K A;  3CC9 A;  4LA6 A;  5CG5 A;  3UCA A;  4ZQ8 A;  2J1O A;  5ILZ A;  4H5C F;  3PDE A;  3G4D A;  3PH7 A;  2O1O A;  3DYH A;  1JFG A;  3M9U A;  3N5J F;  5AYP A;  2OA6 A;  2AZJ A;  2E8W A;  2FOR A;  3P5R A;  1N1B A;  4XQS F;  3KBK A;  2E8V A;  3KRP A;  5A0J A;  5AEL A;  3ACW A;  4XQT F;  5B0M A;  1VG6 A;  4N1Z F;  4LUU A;  4F62 A;  3LGK A;  2E91 A;  3WCJ A;  3N0F A;  3N49 F;  1UBY A;  5EAT A;  4LPH F;  3QKC A;  5HN7 A;  2Z7H A;  3ZCD A;  4MC3 A;  3ICK A;  1DGP A;  1RQI A;  3NPK A;  3SDT A;  2F89 F;  1N20 A;  2Z4X A;  3M01 A;  1V4J A;  2E94 A;  4PVY F;  5A0I A;  4LOB A;  5B0J A;  3N3D A;  4RXC A;  2P1C A;  5JV2 F;  5DZ2 A;  3M02 A;  3KRP B;  3NPR A;  5B01 A;  4RNQ A;  1YQ7 A;  3ZMC A;  2Z52 A;  3EZ3 A;  3TS7 A;  3KRF A;  2PS5 A;  5ILD A;  2E95 A;  5IMI A;  2I19 A;  2E90 A;  3ASX A;  3KRC B;  4LFV F;  4KUX A;  2E8X A;  4GP1 A;  3RYE A;  2AEK A;  1HXC A;  2AZL A;  4H5E F;  4WK5 A;  1KIY A;  3N3L F;  4LZ0 A;  4JZB A;  4LIX A;  4KKM A;  3LGZ B;  3P41 A;  3RYW A;  3WE9 A;  4DI5 A;  5DGM F;  5EAS A;  3SAE A;  3TFN A;  3WCF A;  3Q2Q A;  5IM1 A;  3OAC B;  2AEL A;  3KRO A;  5H9D A;  1DI1 A;  3WJO A;  4MC0 A;  3RMG A;  5ERN A;  5B0I A;  1UBX A;  5CG6 A;  3N1W F;  1YHM A;  3KRF B;  3WJN A;  4KQS A;  4EA2 A;  1RQJ A;  4MC8 A;  3PYB A;  5C05 A;  3N0G A;  3MAV A;  4GA3 A;  2ZEV A;  5E8H A;  2E93 A;  3ICN A;  4OMG A;  3LLW A;  3KB9 A;  4KPD A;  2ZCO A;  4NKE A;  5DGS F;  3ADZ A;  3LZ9 A;  1UBV A;  3NRI A;  3BNX A;  1KIZ A;  3WEG A;  3Q1O A;  3P8L A;  5IKH A;  4K10 A;  3M0G A;  2J5C A;  5IMN A;  3DYG A;  4E9Z A;  4F6V A;  2OPN A;  3ICM A;  3M00 A;  3KRO B;  4DXJ A;  3VJE A;  3IBA A;  3IPI A;  2Z4Y A;  1V4K A;  5IKA A;  2E8U A;  4P0W A;  2F9K F;  5DGN F;  3WCD A;  1PS1 A;  1WL3 A;  4QPF A;  5JV0 F;  3SDV A;  1VG3 A;  2ZCS A;  2Z7I A;  4N9U A;  1HXG A;  5ERM A;  5DIQ F;  3KRC A;  2PS8 A;  4LXW A;  2H8O A;  3PKO A;  5IMP A;  3APZ A;  5KSX F;  4LA5 A;  2F8C F;  3LJI A;  4JXN A;  3WCG A;  4OKM A;  5JUZ F;  3WEI A;  3ZMB A;  3WCM A;  4NFI F;  3P8R A;  3AQC B;  4PVX F;  3LG5 A;  5IL3 A;  1VG7 A;  3OAC A;  3LMD A;  3KRA B;  2Q58 A;  3SDR A;  2Z78 A;  4F6X A;  1V4H A;  4KVW A;  3WSA A;  5IK9 A;  3WCH A;  1WMW A;  3S9V A;  3VJC A;  1YYQ A;  5DW7 A;  4LTZ A;  1WL0 A;  1VG2 A;  5ILK A;  5HN8 A;  4JXY A;  3AE0 A;  5AHU B;  3WCI A;  3WC9 A;  2F92 F;  4KWD A;  4EA1 A;  4RXA A;  2ONG A;  2ZCQ A;  3OAB A;  3WJK A;  4RXE A;  3LEE A;  3WCE A;  1WKZ A;  4GAX A;  1WL2 A;  5IL8 A;  5ER8 A;  5DJP F;  5I1U A;  5B03 A;  4NFJ F;  4RXD A;  1HM7 A;  5DHI A;  1VG4 A;  4DHD A;  5ILY A;  3CP6 A;  4KK2 A;  2E4O A;  4E1E A;  1FPS A;  3OYR A;  4LZ3 A;  1JFA A;  2F7M F;  3VJ9 A;  5E8K A;  4EA0 A;  1HXA A;  5IVG A;  2VF6 A;  2F94 F;  5JA0 F;  3VJB A;  4DEM F;  1YYU A;  5IK0 A;  3OAB B;  3N45 F;  4LZC A;  1N23 A;  3ZL6 A;  4NFK F;  4RYP A;  2Z50 A;  4KVY A;  4FJQ A;  1YHL A;  3B7L A;  2Q9Z A;  1YJ4 A;  2EWG A;  4KPJ A;  4OKZ A;  4LTV A;  3KRA A;  3RBM A;  5B00 A;  2Z4Z A;  3ID0 A;  3EGT A;  4LFG A;  3SDU A;  2QIS A;  1YV5 A;  1WY0 A;  3N6K F;  5ILI A;  3LSN A;  4DWG A;  5IN8 A;  4P0V A;  5HN9 A;  3TFP A;  3VJ8 A;  4KFA A;  4FP4 A;  3EFQ A;  3WEJ A;  5ILH A;  3NF2 A;  4E9U A;  2OGD A;  3VJA A;  4LLS A;  3TFV A;  2Z4W A;  2OPM A;  4JVJ F;  3QQV A;  1N21 A;  4Q23 A;  5DJR F;  3P5P A;  2PS4 A;  1RTR A;  4KVI A;  4LPG F;  4HD1 A;  3V66 A;  3SDQ A;  4KQ5 A;  5DJV F;  5EAU A;  3ZOU A;  1HX9 A;  4OGU A;  3LVS A;  4DWB A;  2RAH A;  3WCL A; 
#chains in the Genus database with same CATH homology
 2AET A;  3MZV A;  3TC1 A;  1ZW5 A;  3WEK A;  3WEF A;  2Q80 A;  3ICZ A;  4LFE A;  2J1P A;  3W7F A;  5B0L A;  5E8L A;  4P0X A;  3WCB A;  4XQR F;  2Z4V A;  1HM4 A;  4GP2 A;  4KQU A;  2F8Z F;  3BNY A;  2AZK A;  3N5H F;  5JV1 F;  5B02 A;  3DYF A;  5HNA A;  2ZY1 A;  3G4F A;  4JYX A;  3CKE A;  1YYR A;  1N24 A;  3WEH A;  3V1X A;  2DH4 A;  5ILJ A;  3WCA A;  2ZEU A;  2E8T A;  1N1Z A;  1YYT A;  2PS7 A;  3LDW A;  5DHK A;  2Q9Y A;  2ONH A;  2PS6 A;  3AQ0 A;  1V4E A;  1UBW A;  5IK6 A;  4OMH A;  5A0K A;  3ACY A;  3LK5 A;  4NKF A;  5ERO A;  2FTZ A;  4L2X F;  3PYA A;  1N22 A;  3V1V A;  4LLT A;  4UMJ A;  3VJD A;  3N46 F;  3AQB B;  3Q2Z A;  4JZX A;  1EZF A;  3N1V F;  1WL1 A;  4QXS F;  3WSB A;  3WCC A;  1V4I A;  3LOM A;  4NG6 A;  1YHK A;  4NUA A;  4KVD A;  2E92 A;  1YYS A;  5AFX A;  3Q30 A;  4H5D F;  3S4J A;  4DZW A;  3ACX A;  2ZCR A;  5B0K A;  3CC9 A;  4LA6 A;  5CG5 A;  3UCA A;  4ZQ8 A;  2J1O A;  5ILZ A;  4H5C F;  3PDE A;  3G4D A;  3PH7 A;  2O1O A;  3DYH A;  1JFG A;  3M9U A;  3N5J F;  5AYP A;  2OA6 A;  2AZJ A;  2E8W A;  2FOR A;  3P5R A;  1N1B A;  4XQS F;  3KBK A;  2E8V A;  3KRP A;  5A0J A;  5AEL A;  3ACW A;  4XQT F;  5B0M A;  1VG6 A;  4N1Z F;  4LUU A;  4F62 A;  3LGK A;  2E91 A;  3WCJ A;  3N0F A;  3N49 F;  1UBY A;  5EAT A;  4LPH F;  3QKC A;  5HN7 A;  2Z7H A;  3ZCD A;  4MC3 A;  3ICK A;  1DGP A;  1RQI A;  3NPK A;  3SDT A;  2F89 F;  1N20 A;  2Z4X A;  3M01 A;  1V4J A;  2E94 A;  4PVY F;  5A0I A;  4LOB A;  5B0J A;  3N3D A;  4RXC A;  2P1C A;  5JV2 F;  5DZ2 A;  3M02 A;  3KRP B;  3NPR A;  5B01 A;  4RNQ A;  1YQ7 A;  3ZMC A;  2Z52 A;  3EZ3 A;  3TS7 A;  3KRF A;  2PS5 A;  5ILD A;  2E95 A;  5IMI A;  2I19 A;  2E90 A;  3ASX A;  3KRC B;  4LFV F;  4KUX A;  2E8X A;  4GP1 A;  3RYE A;  2AEK A;  1HXC A;  2AZL A;  4H5E F;  4WK5 A;  1KIY A;  3N3L F;  4LZ0 A;  4JZB A;  4LIX A;  4KKM A;  3LGZ B;  3P41 A;  3RYW A;  3WE9 A;  4DI5 A;  5DGM F;  5EAS A;  3SAE A;  3TFN A;  3WCF A;  3Q2Q A;  5IM1 A;  3OAC B;  2AEL A;  3KRO A;  5H9D A;  1DI1 A;  3WJO A;  4MC0 A;  3RMG A;  5ERN A;  5B0I A;  1UBX A;  5CG6 A;  3N1W F;  1YHM A;  3KRF B;  3WJN A;  4KQS A;  4EA2 A;  1RQJ A;  4MC8 A;  3PYB A;  5C05 A;  3N0G A;  3MAV A;  4GA3 A;  2ZEV A;  5E8H A;  2E93 A;  3ICN A;  4OMG A;  3LLW A;  3KB9 A;  4KPD A;  2ZCO A;  4NKE A;  5DGS F;  3ADZ A;  3LZ9 A;  1UBV A;  3NRI A;  3BNX A;  1KIZ A;  3WEG A;  3Q1O A;  3P8L A;  5IKH A;  4K10 A;  3M0G A;  2J5C A;  5IMN A;  3DYG A;  4E9Z A;  4F6V A;  2OPN A;  3ICM A;  3M00 A;  3KRO B;  4DXJ A;  3VJE A;  3IBA A;  3IPI A;  2Z4Y A;  1V4K A;  5IKA A;  2E8U A;  4P0W A;  2F9K F;  5DGN F;  3WCD A;  1PS1 A;  1WL3 A;  4QPF A;  5JV0 F;  3SDV A;  1VG3 A;  2ZCS A;  2Z7I A;  4N9U A;  1HXG A;  5ERM A;  5DIQ F;  3KRC A;  2PS8 A;  4LXW A;  2H8O A;  3PKO A;  5IMP A;  3APZ A;  5KSX F;  4LA5 A;  2F8C F;  3LJI A;  4JXN A;  3WCG A;  4OKM A;  5JUZ F;  3WEI A;  3ZMB A;  3WCM A;  4NFI F;  3P8R A;  3AQC B;  4PVX F;  3LG5 A;  5IL3 A;  1VG7 A;  3OAC A;  3LMD A;  3KRA B;  2Q58 A;  3SDR A;  2Z78 A;  4F6X A;  1V4H A;  4KVW A;  3WSA A;  5IK9 A;  3WCH A;  1WMW A;  3S9V A;  3VJC A;  1YYQ A;  5DW7 A;  4LTZ A;  1WL0 A;  1VG2 A;  5ILK A;  5HN8 A;  4JXY A;  3AE0 A;  5AHU B;  3WCI A;  3WC9 A;  2F92 F;  4KWD A;  4EA1 A;  4RXA A;  2ONG A;  2ZCQ A;  3OAB A;  3WJK A;  4RXE A;  3LEE A;  3WCE A;  1WKZ A;  4GAX A;  1WL2 A;  5IL8 A;  5ER8 A;  5DJP F;  5I1U A;  5B03 A;  4NFJ F;  4RXD A;  1HM7 A;  5DHI A;  1VG4 A;  4DHD A;  5ILY A;  3CP6 A;  4KK2 A;  2E4O A;  4E1E A;  1FPS A;  3OYR A;  4LZ3 A;  1JFA A;  2F7M F;  3VJ9 A;  5E8K A;  4EA0 A;  1HXA A;  5IVG A;  2VF6 A;  2F94 F;  5JA0 F;  3VJB A;  4DEM F;  1YYU A;  5IK0 A;  3OAB B;  3N45 F;  4LZC A;  1N23 A;  3ZL6 A;  4NFK F;  4RYP A;  2Z50 A;  4KVY A;  4FJQ A;  1YHL A;  3B7L A;  2Q9Z A;  1YJ4 A;  2EWG A;  4KPJ A;  4OKZ A;  4LTV A;  3KRA A;  3RBM A;  5B00 A;  2Z4Z A;  3ID0 A;  3EGT A;  4LFG A;  3SDU A;  2QIS A;  1YV5 A;  1WY0 A;  3N6K F;  5ILI A;  3LSN A;  4DWG A;  5IN8 A;  4P0V A;  5HN9 A;  3TFP A;  3VJ8 A;  4KFA A;  4FP4 A;  3EFQ A;  3WEJ A;  5ILH A;  3NF2 A;  4E9U A;  2OGD A;  3VJA A;  4LLS A;  3TFV A;  2Z4W A;  2OPM A;  4JVJ F;  3QQV A;  1N21 A;  4Q23 A;  5DJR F;  3P5P A;  2PS4 A;  1RTR A;  4KVI A;  4LPG F;  4HD1 A;  3V66 A;  3SDQ A;  4KQ5 A;  5DJV F;  5EAU A;  3ZOU A;  1HX9 A;  4OGU A;  3LVS A;  4DWB A;  2RAH A;  3WCL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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