2AETA

R304k trichodiene synthase: complex with mg, pyrophosphate, and (4s)-7-azabisabolene
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
352
structure length
352
Chain Sequence
NFPTEYFLNTTVRLLEYIRYRDSNYTREERIENLHYAYNKAAHHFAQPRQQQLLKVDPKRLQASLQTIVGMVVYSWAKVSKECMADLSIHYTYTLVLDDSKDDPYPTMVNYFDDLQAGREQAHPWWALVNEHFPNVLRHFGPFCSLNLIRSTLDFFEGCWIEQYNFGGFPGSHDYPQFLRRMNGLGHCVGASLWPKEQFNERSLFLEITSAIAQMENWMVWVNDLMSFYKEFDDERDQISLVKNYVVSDEISLHEALEKLTQDTLHSSKQMVAVFSDKDPQVMDTIECFMHGYVTWHLCDRKYRLSEIYEKVKEEKTEDAQKFCKFYEQAANVGAVSPSEWAYPPVAQLANV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Role of arginine-304 in the diphosphate-triggered active site closure mechanism of trichodiene synthase.
pubmed doi rcsb
molecule keywords Trichodiene synthase
molecule tags Lyase
source organism Fusarium sporotrichioides
total genus 145
structure length 352
sequence length 352
chains with identical sequence B
ec nomenclature ec 4.2.3.6: Trichodiene synthase.
pdb deposition date 2005-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06330 TRI5 Trichodiene synthase (TRI5)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2aetA00
3WSAA 4F62A 4P0VA 4N1ZF 2Q58A 4H5CF 3NPRA 4GP2A 3NF2A 2F8ZF 3DYFA 1N20A 2E94A 5EASA 3LVSA 5IN8A 3QKCA 3KRAB 4NKEA 4RXAA 3WCFA 3EFQA 3N46F 3RMGA 5KSXF 5DW7A 1WL1A 3LGKA 3PYBA 5CG6A 1VG7A 2OPNA 4NFJF 3WEHA 1V4IA 1HXAA 3AQBB 1N1BA 4NFIF 2PS7A 4KWDA 4OMGA 1HXCA 1EZFA 1YYRA 4RXEA 3WEJA 5ILKA 2ONHA 3TS7A 3S9VA 2ZY1A 4EA0A 2F8CF 5IL8A 3SDRA 5B01A 1FPSA 3AQ0A 1VG4A 1VG2A 4KVIA 2ZCSA 1UBYA 5ILHA 4L2XF 5B0IA 4XQRF 3LSNA 4JXNA 1DGPA 4MC3A 2ONGA 3KBKA 2AELA 3WSBA 4N9UA 5IMPA 4DI5A 3DYGA 5IKAA 5C05A 5ILIA 2E8TA 5AYPA 5DHKA 1YHLA 2RAHA 3KRPB 5DGMF 2E8XA 1RTRA 3M02A 3KROB 3KRPA 3P8RA 1N1ZA 3P5RA 3N1WF 3ICKA 4LIXA 3ICNA 3KROA 1WKZA 3VJEA 4JZBA 3Q30A 3P41A 3ZCDA 2E91A 5ILYA 1YV5A 4EA2A 2FTZA 2Z4XA 2E92A 4NKFA 2OA6A 5IK6A 2F7MF 3ICZA 3IPIA 3WCGA 1KIZA 4LXWA 5IMIA 1V4KA 3IBAA 5IMNA 1V4EA 3VJCA 3KRCB 4UMJA 1DI1A 3KB9A 3KRCA 3Q2ZA 2OPMA 4HD1A 2E8WA 3SDUA 4DXJA 1YHKA 3ASXA 2F92F 5DGNF 3NPKA 3CKEA 3N45F 4EA1A 5H9DA 2ZEVA 3KRFB 4GA3A 3WC9A 3PDEA 5DIQF 2F89F 5IKHA 5IL3A 4P0WA 3PH7A 5JUZF 3KRFA 2J1PA 3LG5A 3BNYA 2OGDA 2FORA 4Q23A 4ZQ8A 4DHDA 4RXDA 5ILZA 4LPHF 5A0KA 2E93A 3N3LF 3WEGA 4RYPA 5E8LA 1VG3A 4NUAA 3UCAA 1HXGA 3M9UA 5DGSF 2Q9ZA 4E9ZA 2Z52A 5B00A 2J5CA 4LA5A 3Q2QA 3ZOUA 5I1UA 3LDWA 2Z4WA 3VJ8A 1VG6A 3QQVA 5JA0F 2J1OA 5DHIA 3WCLA 4LLTA 3N0GA 4JXYA 5HN8A 4KVYA 2E8UA 3N49F 3RYWA 2ZCOA 4KQUA 3VJDA 4OKZA 3PYAA 3G4FA 2I19A 2Q80A 3SDTA 3DYHA 3TFNA 4KUXA 3RBMA 3BNXA 5EAUA 5AELA 3N0FA 4RNQA 3EGTA 1V4JA 3AE0A 4FP4A 1JFAA 2PS4A 1YJ4A 1HM7A 4LFVF 2AZLA 2AZJA 5IK0A 2Z7HA 4KQ5A 3VJBA 4MC0A 2AZKA 3N5JF 2H8OA 1UBXA 5HNAA 5B0JA 4F6VA 1N23A 5ILJA 2F94F 4OGUA 3WCHA 4LTZA 4H5DF 3P5PA 5A0IA 3OACB 2VF6A 5ILDA 3TC1A 3LOMA 1RQIA 3CC9A 3OACA 3M01A 4LPGF 1PS1A 5DJRF 4F6XA 4FJQA 5JV0F 3WEFA 3AQCB 5HN7A 3WCJA 5JV1F 2P1CA 2ZEUA 3ZL6A 4NG6A 3LJIA 4QPFA 4GP1A 3OABB 4QXSF 1YYSA 2EWGA 5ERNA 1V4HA 2AETA 3WCBA 4KVDA 3OABA 4LFEA 4LA6A 3WE9A 1N21A 2QISA 3M00A 3P8LA 1UBWA 3EZ3A 5AHUB 3APZA 1YYUA 3WCIA 3WCDA 3OYRA 3CP6A 4RXCA 2PS5A 4JYXA 3SDVA 1N22A 3LGZB 4LZ0A 3LK5A 2O1OA 1WL3A 5E8HA 1N24A 3WEIA 3SDQA 4E9UA 4KK2A 4LZCA 5ERMA 5DJPF 3LZ9A 4MC8A 1YYQA 3ICMA 3ADZA 2Q9YA 3MAVA 1WY0A 2Z4ZA 4KPDA 4XQSF 2ZCQA 4PVYF 3SAEA 3KRAA 5IM1A 2E4OA 3V1VA 3V66A 5DJVF 3WJNA 4P0XA 4JZXA 2Z4YA 3TFPA 1UBVA 3LEEA 5HN9A 3VJAA 3ACYA 3WJOA 3MZVA 2Z50A 4LFGA 4KQSA 4LZ3A 2AEKA 4OKMA 5EROA 2E90A 4LUUA 3N6KF 4NFKF 1ZW5A 3N1VF 3ACWA 5IK9A 3ID0A 3G4DA 5B02A 4JVJF 2E95A 4DZWA 1HX9A 2E8VA 4KFAA 5B0MA 1KIYA 3W7FA 2F9KF 4KKMA 4DWGA 4LOBA 2PS6A 2PS8A 3N3DA 1WL0A 3N5HF 4LTVA 3VJ9A 1WMWA 5A0JA 3NRIA 4GAXA 3TFVA 3WEKA 3ZMBA 4DEMF 5B0LA 4K10A 5JV2F 1RQJA 1YHMA 2ZCRA 5DZ2A 3V1XA 3S4JA 5E8KA 3PKOA 4OMHA 4DWBA 1YYTA 3Q1OA 3WCCA 3RYEA 5EATA 3B7LA 5IVGA 3WCAA 1YQ7A 4H5EF 4KPJA 1JFGA 4E1EA 4LLSA 5CG5A 5AFXA 3M0GA 2Z4VA 3WCMA 3LLWA 3WJKA 5B03A 3WCEA 5B0KA 3ACXA 1HM4A 4PVXF 4KVWA 2Z78A 4XQTF 2Z7IA 4WK5A 5ER8A 1WL2A 3LMDA 3ZMCA 2DH4A
chains in the Genus database with same CATH superfamily
3WSAA 4F62A 4P0VA 4N1ZF 2Q58A 4H5CF 3NPRA 4GP2A 3NF2A 2F8ZF 3DYFA 1N20A 2E94A 5EASA 3LVSA 5IN8A 3QKCA 3KRAB 4NKEA 4RXAA 3WCFA 3EFQA 3N46F 3RMGA 5KSXF 5DW7A 1WL1A 3LGKA 3PYBA 5CG6A 1VG7A 2OPNA 4NFJF 3WEHA 1V4IA 1HXAA 3AQBB 1N1BA 4NFIF 2PS7A 4KWDA 4OMGA 1HXCA 1EZFA 1YYRA 4RXEA 3WEJA 5ILKA 2ONHA 3TS7A 3S9VA 2ZY1A 4EA0A 2F8CF 5IL8A 3SDRA 5B01A 1FPSA 3AQ0A 1VG4A 1VG2A 4KVIA 2ZCSA 1UBYA 5ILHA 4L2XF 5B0IA 4XQRF 3LSNA 4JXNA 1DGPA 4MC3A 2ONGA 3KBKA 2AELA 3WSBA 4N9UA 5IMPA 4DI5A 3DYGA 5IKAA 5C05A 5ILIA 2E8TA 5AYPA 5DHKA 1YHLA 2RAHA 3KRPB 5DGMF 2E8XA 1RTRA 3M02A 3KROB 3KRPA 3P8RA 1N1ZA 3P5RA 3N1WF 3ICKA 4LIXA 3ICNA 3KROA 1WKZA 3VJEA 4JZBA 3Q30A 3P41A 3ZCDA 2E91A 5ILYA 1YV5A 4EA2A 2FTZA 2Z4XA 2E92A 4NKFA 2OA6A 5IK6A 2F7MF 3ICZA 3IPIA 3WCGA 1KIZA 4LXWA 5IMIA 1V4KA 3IBAA 5IMNA 1V4EA 3VJCA 3KRCB 4UMJA 1DI1A 3KB9A 3KRCA 3Q2ZA 2OPMA 4HD1A 2E8WA 3SDUA 4DXJA 1YHKA 3ASXA 2F92F 5DGNF 3NPKA 3CKEA 3N45F 4EA1A 5H9DA 2ZEVA 3KRFB 4GA3A 3WC9A 3PDEA 5DIQF 2F89F 5IKHA 5IL3A 4P0WA 3PH7A 5JUZF 3KRFA 2J1PA 3LG5A 3BNYA 2OGDA 2FORA 4Q23A 4ZQ8A 4DHDA 4RXDA 5ILZA 4LPHF 5A0KA 2E93A 3N3LF 3WEGA 4RYPA 5E8LA 1VG3A 4NUAA 3UCAA 1HXGA 3M9UA 5DGSF 2Q9ZA 4E9ZA 2Z52A 5B00A 2J5CA 4LA5A 3Q2QA 3ZOUA 5I1UA 3LDWA 2Z4WA 3VJ8A 1VG6A 3QQVA 5JA0F 2J1OA 5DHIA 3WCLA 4LLTA 3N0GA 4JXYA 5HN8A 4KVYA 2E8UA 3N49F 3RYWA 2ZCOA 4KQUA 3VJDA 4OKZA 3PYAA 3G4FA 2I19A 2Q80A 3SDTA 3DYHA 3TFNA 4KUXA 3RBMA 3BNXA 5EAUA 5AELA 3N0FA 4RNQA 3EGTA 1V4JA 3AE0A 4FP4A 1JFAA 2PS4A 1YJ4A 1HM7A 4LFVF 2AZLA 2AZJA 5IK0A 2Z7HA 4KQ5A 3VJBA 4MC0A 2AZKA 3N5JF 2H8OA 1UBXA 5HNAA 5B0JA 4F6VA 1N23A 5ILJA 2F94F 4OGUA 3WCHA 4LTZA 4H5DF 3P5PA 5A0IA 3OACB 2VF6A 5ILDA 3TC1A 3LOMA 1RQIA 3CC9A 3OACA 3M01A 4LPGF 1PS1A 5DJRF 4F6XA 4FJQA 5JV0F 3WEFA 3AQCB 5HN7A 3WCJA 5JV1F 2P1CA 2ZEUA 3ZL6A 4NG6A 3LJIA 4QPFA 4GP1A 3OABB 4QXSF 1YYSA 2EWGA 5ERNA 1V4HA 2AETA 3WCBA 4KVDA 3OABA 4LFEA 4LA6A 3WE9A 1N21A 2QISA 3M00A 3P8LA 1UBWA 3EZ3A 5AHUB 3APZA 1YYUA 3WCIA 3WCDA 3OYRA 3CP6A 4RXCA 2PS5A 4JYXA 3SDVA 1N22A 3LGZB 4LZ0A 3LK5A 2O1OA 1WL3A 5E8HA 1N24A 3WEIA 3SDQA 4E9UA 4KK2A 4LZCA 5ERMA 5DJPF 3LZ9A 4MC8A 1YYQA 3ICMA 3ADZA 2Q9YA 3MAVA 1WY0A 2Z4ZA 4KPDA 4XQSF 2ZCQA 4PVYF 3SAEA 3KRAA 5IM1A 2E4OA 3V1VA 3V66A 5DJVF 3WJNA 4P0XA 4JZXA 2Z4YA 3TFPA 1UBVA 3LEEA 5HN9A 3VJAA 3ACYA 3WJOA 3MZVA 2Z50A 4LFGA 4KQSA 4LZ3A 2AEKA 4OKMA 5EROA 2E90A 4LUUA 3N6KF 4NFKF 1ZW5A 3N1VF 3ACWA 5IK9A 3ID0A 3G4DA 5B02A 4JVJF 2E95A 4DZWA 1HX9A 2E8VA 4KFAA 5B0MA 1KIYA 3W7FA 2F9KF 4KKMA 4DWGA 4LOBA 2PS6A 2PS8A 3N3DA 1WL0A 3N5HF 4LTVA 3VJ9A 1WMWA 5A0JA 3NRIA 4GAXA 3TFVA 3WEKA 3ZMBA 4DEMF 5B0LA 4K10A 5JV2F 1RQJA 1YHMA 2ZCRA 5DZ2A 3V1XA 3S4JA 5E8KA 3PKOA 4OMHA 4DWBA 1YYTA 3Q1OA 3WCCA 3RYEA 5EATA 3B7LA 5IVGA 3WCAA 1YQ7A 4H5EF 4KPJA 1JFGA 4E1EA 4LLSA 5CG5A 5AFXA 3M0GA 2Z4VA 3WCMA 3LLWA 3WJKA 5B03A 3WCEA 5B0KA 3ACXA 1HM4A 4PVXF 4KVWA 2Z78A 4XQTF 2Z7IA 4WK5A 5ER8A 1WL2A 3LMDA 3ZMCA 2DH4A
chains in the Genus database with same CATH topology
3WSAA 4F62A 4P0VA 4N1ZF 2Q58A 4H5CF 3NPRA 4GP2A 3NF2A 2F8ZF 3DYFA 1N20A 2E94A 5EASA 3LVSA 5IN8A 3QKCA 3KRAB 4NKEA 4RXAA 3WCFA 3EFQA 3N46F 3RMGA 5KSXF 5DW7A 1WL1A 3LGKA 3PYBA 5CG6A 1VG7A 2OPNA 4NFJF 3WEHA 1V4IA 1HXAA 3AQBB 1N1BA 4NFIF 2PS7A 4KWDA 4OMGA 1HXCA 1EZFA 1YYRA 4RXEA 3WEJA 5ILKA 2ONHA 3TS7A 3S9VA 2ZY1A 4EA0A 2F8CF 5IL8A 3SDRA 5B01A 1FPSA 3AQ0A 1VG4A 1VG2A 4KVIA 2ZCSA 1UBYA 5ILHA 4L2XF 5B0IA 4XQRF 3LSNA 4JXNA 1DGPA 4MC3A 2ONGA 3KBKA 2AELA 3WSBA 4N9UA 5IMPA 4DI5A 3DYGA 5IKAA 5C05A 5ILIA 2E8TA 5AYPA 5DHKA 1YHLA 2RAHA 3KRPB 5DGMF 2E8XA 1RTRA 3M02A 3KROB 3KRPA 3P8RA 1N1ZA 3P5RA 3N1WF 3ICKA 4LIXA 3ICNA 3KROA 1WKZA 3VJEA 4JZBA 3Q30A 3P41A 3ZCDA 2E91A 5ILYA 1YV5A 4EA2A 2FTZA 2Z4XA 2E92A 4NKFA 2OA6A 5IK6A 2F7MF 3ICZA 3IPIA 3WCGA 1KIZA 4LXWA 5IMIA 1V4KA 3IBAA 5IMNA 1V4EA 3VJCA 3KRCB 4UMJA 1DI1A 3KB9A 3KRCA 3Q2ZA 2OPMA 4HD1A 2E8WA 3SDUA 4DXJA 1YHKA 3ASXA 2F92F 5DGNF 3NPKA 3CKEA 3N45F 4EA1A 5H9DA 2ZEVA 3KRFB 4GA3A 3WC9A 3PDEA 5DIQF 2F89F 5IKHA 5IL3A 4P0WA 3PH7A 5JUZF 3KRFA 2J1PA 3LG5A 3BNYA 2OGDA 2FORA 4Q23A 4ZQ8A 4DHDA 4RXDA 5ILZA 4LPHF 5A0KA 2E93A 3N3LF 3WEGA 4RYPA 5E8LA 1VG3A 4NUAA 3UCAA 1HXGA 3M9UA 5DGSF 2Q9ZA 4E9ZA 2Z52A 5B00A 2J5CA 4LA5A 3Q2QA 3ZOUA 5I1UA 3LDWA 2Z4WA 3VJ8A 1VG6A 3QQVA 5JA0F 2J1OA 5DHIA 3WCLA 4LLTA 3N0GA 4JXYA 5HN8A 4KVYA 2E8UA 3N49F 3RYWA 2ZCOA 4KQUA 3VJDA 4OKZA 3PYAA 3G4FA 2I19A 2Q80A 3SDTA 3DYHA 3TFNA 4KUXA 3RBMA 3BNXA 5EAUA 5AELA 3N0FA 4RNQA 3EGTA 1V4JA 3AE0A 4FP4A 1JFAA 2PS4A 1YJ4A 1HM7A 4LFVF 2AZLA 2AZJA 5IK0A 2Z7HA 4KQ5A 3VJBA 4MC0A 2AZKA 3N5JF 2H8OA 1UBXA 5HNAA 5B0JA 4F6VA 1N23A 5ILJA 2F94F 4OGUA 3WCHA 4LTZA 4H5DF 3P5PA 5A0IA 3OACB 2VF6A 5ILDA 3TC1A 3LOMA 1RQIA 3CC9A 3OACA 3M01A 4LPGF 1PS1A 5DJRF 4F6XA 4FJQA 5JV0F 3WEFA 3AQCB 5HN7A 3WCJA 5JV1F 2P1CA 2ZEUA 3ZL6A 4NG6A 3LJIA 4QPFA 4GP1A 3OABB 4QXSF 1YYSA 2EWGA 5ERNA 1V4HA 2AETA 3WCBA 4KVDA 3OABA 4LFEA 4LA6A 3WE9A 1N21A 2QISA 3M00A 3P8LA 1UBWA 3EZ3A 5AHUB 3APZA 1YYUA 3WCIA 3WCDA 3OYRA 3CP6A 4RXCA 2PS5A 4JYXA 3SDVA 1N22A 3LGZB 4LZ0A 3LK5A 2O1OA 1WL3A 5E8HA 1N24A 3WEIA 3SDQA 4E9UA 4KK2A 4LZCA 5ERMA 5DJPF 3LZ9A 4MC8A 1YYQA 3ICMA 3ADZA 2Q9YA 3MAVA 1WY0A 2Z4ZA 4KPDA 4XQSF 2ZCQA 4PVYF 3SAEA 3KRAA 5IM1A 2E4OA 3V1VA 3V66A 5DJVF 3WJNA 4P0XA 4JZXA 2Z4YA 3TFPA 1UBVA 3LEEA 5HN9A 3VJAA 3ACYA 3WJOA 3MZVA 2Z50A 4LFGA 4KQSA 4LZ3A 2AEKA 4OKMA 5EROA 2E90A 4LUUA 3N6KF 4NFKF 1ZW5A 3N1VF 3ACWA 5IK9A 3ID0A 3G4DA 5B02A 4JVJF 2E95A 4DZWA 1HX9A 2E8VA 4KFAA 5B0MA 1KIYA 3W7FA 2F9KF 4KKMA 4DWGA 4LOBA 2PS6A 2PS8A 3N3DA 1WL0A 3N5HF 4LTVA 3VJ9A 1WMWA 5A0JA 3NRIA 4GAXA 3TFVA 3WEKA 3ZMBA 4DEMF 5B0LA 4K10A 5JV2F 1RQJA 1YHMA 2ZCRA 5DZ2A 3V1XA 3S4JA 5E8KA 3PKOA 4OMHA 4DWBA 1YYTA 3Q1OA 3WCCA 3RYEA 5EATA 3B7LA 5IVGA 3WCAA 1YQ7A 4H5EF 4KPJA 1JFGA 4E1EA 4LLSA 5CG5A 5AFXA 3M0GA 2Z4VA 3WCMA 3LLWA 3WJKA 5B03A 3WCEA 5B0KA 3ACXA 1HM4A 4PVXF 4KVWA 2Z78A 4XQTF 2Z7IA 4WK5A 5ER8A 1WL2A 3LMDA 3ZMCA 2DH4A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3WSA A;  4F62 A;  4P0V A;  4N1Z F;  2Q58 A;  4H5C F;  3NPR A;  4GP2 A;  3NF2 A;  2F8Z F;  3DYF A;  1N20 A;  2E94 A;  5EAS A;  3LVS A;  5IN8 A;  3QKC A;  3KRA B;  4NKE A;  4RXA A;  3WCF A;  3EFQ A;  3N46 F;  3RMG A;  5KSX F;  5DW7 A;  1WL1 A;  3LGK A;  3PYB A;  5CG6 A;  1VG7 A;  2OPN A;  4NFJ F;  3WEH A;  1V4I A;  1HXA A;  3AQB B;  1N1B A;  4NFI F;  2PS7 A;  4KWD A;  4OMG A;  1HXC A;  1EZF A;  1YYR A;  4RXE A;  3WEJ A;  5ILK A;  2ONH A;  3TS7 A;  3S9V A;  2ZY1 A;  4EA0 A;  2F8C F;  5IL8 A;  3SDR A;  5B01 A;  1FPS A;  3AQ0 A;  1VG4 A;  1VG2 A;  4KVI A;  2ZCS A;  1UBY A;  5ILH A;  4L2X F;  5B0I A;  4XQR F;  3LSN A;  4JXN A;  1DGP A;  4MC3 A;  2ONG A;  3KBK A;  2AEL A;  3WSB A;  4N9U A;  5IMP A;  4DI5 A;  3DYG A;  5IKA A;  5C05 A;  5ILI A;  2E8T A;  5AYP A;  5DHK A;  1YHL A;  2RAH A;  3KRP B;  5DGM F;  2E8X A;  1RTR A;  3M02 A;  3KRO B;  3KRP A;  3P8R A;  1N1Z A;  3P5R A;  3N1W F;  3ICK A;  4LIX A;  3ICN A;  3KRO A;  1WKZ A;  3VJE A;  4JZB A;  3Q30 A;  3P41 A;  3ZCD A;  2E91 A;  5ILY A;  1YV5 A;  4EA2 A;  2FTZ A;  2Z4X A;  2E92 A;  4NKF A;  2OA6 A;  5IK6 A;  2F7M F;  3ICZ A;  3IPI A;  3WCG A;  1KIZ A;  4LXW A;  5IMI A;  1V4K A;  3IBA A;  5IMN A;  1V4E A;  3VJC A;  3KRC B;  4UMJ A;  1DI1 A;  3KB9 A;  3KRC A;  3Q2Z A;  2OPM A;  4HD1 A;  2E8W A;  3SDU A;  4DXJ A;  1YHK A;  3ASX A;  2F92 F;  5DGN F;  3NPK A;  3CKE A;  3N45 F;  4EA1 A;  5H9D A;  2ZEV A;  3KRF B;  4GA3 A;  3WC9 A;  3PDE A;  5DIQ F;  2F89 F;  5IKH A;  5IL3 A;  4P0W A;  3PH7 A;  5JUZ F;  3KRF A;  2J1P A;  3LG5 A;  3BNY A;  2OGD A;  2FOR A;  4Q23 A;  4ZQ8 A;  4DHD A;  4RXD A;  5ILZ A;  4LPH F;  5A0K A;  2E93 A;  3N3L F;  3WEG A;  4RYP A;  5E8L A;  1VG3 A;  4NUA A;  3UCA A;  1HXG A;  3M9U A;  5DGS F;  2Q9Z A;  4E9Z A;  2Z52 A;  5B00 A;  2J5C A;  4LA5 A;  3Q2Q A;  3ZOU A;  5I1U A;  3LDW A;  2Z4W A;  3VJ8 A;  1VG6 A;  3QQV A;  5JA0 F;  2J1O A;  5DHI A;  3WCL A;  4LLT A;  3N0G A;  4JXY A;  5HN8 A;  4KVY A;  2E8U A;  3N49 F;  3RYW A;  2ZCO A;  4KQU A;  3VJD A;  4OKZ A;  3PYA A;  3G4F A;  2I19 A;  2Q80 A;  3SDT A;  3DYH A;  3TFN A;  4KUX A;  3RBM A;  3BNX A;  5EAU A;  5AEL A;  3N0F A;  4RNQ A;  3EGT A;  1V4J A;  3AE0 A;  4FP4 A;  1JFA A;  2PS4 A;  1YJ4 A;  1HM7 A;  4LFV F;  2AZL A;  2AZJ A;  5IK0 A;  2Z7H A;  4KQ5 A;  3VJB A;  4MC0 A;  2AZK A;  3N5J F;  2H8O A;  1UBX A;  5HNA A;  5B0J A;  4F6V A;  1N23 A;  5ILJ A;  2F94 F;  4OGU A;  3WCH A;  4LTZ A;  4H5D F;  3P5P A;  5A0I A;  3OAC B;  2VF6 A;  5ILD A;  3TC1 A;  3LOM A;  1RQI A;  3CC9 A;  3OAC A;  3M01 A;  4LPG F;  1PS1 A;  5DJR F;  4F6X A;  4FJQ A;  5JV0 F;  3WEF A;  3AQC B;  5HN7 A;  3WCJ A;  5JV1 F;  2P1C A;  2ZEU A;  3ZL6 A;  4NG6 A;  3LJI A;  4QPF A;  4GP1 A;  3OAB B;  4QXS F;  1YYS A;  2EWG A;  5ERN A;  1V4H A;  2AET A;  3WCB A;  4KVD A;  3OAB A;  4LFE A;  4LA6 A;  3WE9 A;  1N21 A;  2QIS A;  3M00 A;  3P8L A;  1UBW A;  3EZ3 A;  5AHU B;  3APZ A;  1YYU A;  3WCI A;  3WCD A;  3OYR A;  3CP6 A;  4RXC A;  2PS5 A;  4JYX A;  3SDV A;  1N22 A;  3LGZ B;  4LZ0 A;  3LK5 A;  2O1O A;  1WL3 A;  5E8H A;  1N24 A;  3WEI A;  3SDQ A;  4E9U A;  4KK2 A;  4LZC A;  5ERM A;  5DJP F;  3LZ9 A;  4MC8 A;  1YYQ A;  3ICM A;  3ADZ A;  2Q9Y A;  3MAV A;  1WY0 A;  2Z4Z A;  4KPD A;  4XQS F;  2ZCQ A;  4PVY F;  3SAE A;  3KRA A;  5IM1 A;  2E4O A;  3V1V A;  3V66 A;  5DJV F;  3WJN A;  4P0X A;  4JZX A;  2Z4Y A;  3TFP A;  1UBV A;  3LEE A;  5HN9 A;  3VJA A;  3ACY A;  3WJO A;  3MZV A;  2Z50 A;  4LFG A;  4KQS A;  4LZ3 A;  2AEK A;  4OKM A;  5ERO A;  2E90 A;  4LUU A;  3N6K F;  4NFK F;  1ZW5 A;  3N1V F;  3ACW A;  5IK9 A;  3ID0 A;  3G4D A;  5B02 A;  4JVJ F;  2E95 A;  4DZW A;  1HX9 A;  2E8V A;  4KFA A;  5B0M A;  1KIY A;  3W7F A;  2F9K F;  4KKM A;  4DWG A;  4LOB A;  2PS6 A;  2PS8 A;  3N3D A;  1WL0 A;  3N5H F;  4LTV A;  3VJ9 A;  1WMW A;  5A0J A;  3NRI A;  4GAX A;  3TFV A;  3WEK A;  3ZMB A;  4DEM F;  5B0L A;  4K10 A;  5JV2 F;  1RQJ A;  1YHM A;  2ZCR A;  5DZ2 A;  3V1X A;  3S4J A;  5E8K A;  3PKO A;  4OMH A;  4DWB A;  1YYT A;  3Q1O A;  3WCC A;  3RYE A;  5EAT A;  3B7L A;  5IVG A;  3WCA A;  1YQ7 A;  4H5E F;  4KPJ A;  1JFG A;  4E1E A;  4LLS A;  5CG5 A;  5AFX A;  3M0G A;  2Z4V A;  3WCM A;  3LLW A;  3WJK A;  5B03 A;  3WCE A;  5B0K A;  3ACX A;  1HM4 A;  4PVX F;  4KVW A;  2Z78 A;  4XQT F;  2Z7I A;  4WK5 A;  5ER8 A;  1WL2 A;  3LMD A;  3ZMC A;  2DH4 A; 
#chains in the Genus database with same CATH topology
 3WSA A;  4F62 A;  4P0V A;  4N1Z F;  2Q58 A;  4H5C F;  3NPR A;  4GP2 A;  3NF2 A;  2F8Z F;  3DYF A;  1N20 A;  2E94 A;  5EAS A;  3LVS A;  5IN8 A;  3QKC A;  3KRA B;  4NKE A;  4RXA A;  3WCF A;  3EFQ A;  3N46 F;  3RMG A;  5KSX F;  5DW7 A;  1WL1 A;  3LGK A;  3PYB A;  5CG6 A;  1VG7 A;  2OPN A;  4NFJ F;  3WEH A;  1V4I A;  1HXA A;  3AQB B;  1N1B A;  4NFI F;  2PS7 A;  4KWD A;  4OMG A;  1HXC A;  1EZF A;  1YYR A;  4RXE A;  3WEJ A;  5ILK A;  2ONH A;  3TS7 A;  3S9V A;  2ZY1 A;  4EA0 A;  2F8C F;  5IL8 A;  3SDR A;  5B01 A;  1FPS A;  3AQ0 A;  1VG4 A;  1VG2 A;  4KVI A;  2ZCS A;  1UBY A;  5ILH A;  4L2X F;  5B0I A;  4XQR F;  3LSN A;  4JXN A;  1DGP A;  4MC3 A;  2ONG A;  3KBK A;  2AEL A;  3WSB A;  4N9U A;  5IMP A;  4DI5 A;  3DYG A;  5IKA A;  5C05 A;  5ILI A;  2E8T A;  5AYP A;  5DHK A;  1YHL A;  2RAH A;  3KRP B;  5DGM F;  2E8X A;  1RTR A;  3M02 A;  3KRO B;  3KRP A;  3P8R A;  1N1Z A;  3P5R A;  3N1W F;  3ICK A;  4LIX A;  3ICN A;  3KRO A;  1WKZ A;  3VJE A;  4JZB A;  3Q30 A;  3P41 A;  3ZCD A;  2E91 A;  5ILY A;  1YV5 A;  4EA2 A;  2FTZ A;  2Z4X A;  2E92 A;  4NKF A;  2OA6 A;  5IK6 A;  2F7M F;  3ICZ A;  3IPI A;  3WCG A;  1KIZ A;  4LXW A;  5IMI A;  1V4K A;  3IBA A;  5IMN A;  1V4E A;  3VJC A;  3KRC B;  4UMJ A;  1DI1 A;  3KB9 A;  3KRC A;  3Q2Z A;  2OPM A;  4HD1 A;  2E8W A;  3SDU A;  4DXJ A;  1YHK A;  3ASX A;  2F92 F;  5DGN F;  3NPK A;  3CKE A;  3N45 F;  4EA1 A;  5H9D A;  2ZEV A;  3KRF B;  4GA3 A;  3WC9 A;  3PDE A;  5DIQ F;  2F89 F;  5IKH A;  5IL3 A;  4P0W A;  3PH7 A;  5JUZ F;  3KRF A;  2J1P A;  3LG5 A;  3BNY A;  2OGD A;  2FOR A;  4Q23 A;  4ZQ8 A;  4DHD A;  4RXD A;  5ILZ A;  4LPH F;  5A0K A;  2E93 A;  3N3L F;  3WEG A;  4RYP A;  5E8L A;  1VG3 A;  4NUA A;  3UCA A;  1HXG A;  3M9U A;  5DGS F;  2Q9Z A;  4E9Z A;  2Z52 A;  5B00 A;  2J5C A;  4LA5 A;  3Q2Q A;  3ZOU A;  5I1U A;  3LDW A;  2Z4W A;  3VJ8 A;  1VG6 A;  3QQV A;  5JA0 F;  2J1O A;  5DHI A;  3WCL A;  4LLT A;  3N0G A;  4JXY A;  5HN8 A;  4KVY A;  2E8U A;  3N49 F;  3RYW A;  2ZCO A;  4KQU A;  3VJD A;  4OKZ A;  3PYA A;  3G4F A;  2I19 A;  2Q80 A;  3SDT A;  3DYH A;  3TFN A;  4KUX A;  3RBM A;  3BNX A;  5EAU A;  5AEL A;  3N0F A;  4RNQ A;  3EGT A;  1V4J A;  3AE0 A;  4FP4 A;  1JFA A;  2PS4 A;  1YJ4 A;  1HM7 A;  4LFV F;  2AZL A;  2AZJ A;  5IK0 A;  2Z7H A;  4KQ5 A;  3VJB A;  4MC0 A;  2AZK A;  3N5J F;  2H8O A;  1UBX A;  5HNA A;  5B0J A;  4F6V A;  1N23 A;  5ILJ A;  2F94 F;  4OGU A;  3WCH A;  4LTZ A;  4H5D F;  3P5P A;  5A0I A;  3OAC B;  2VF6 A;  5ILD A;  3TC1 A;  3LOM A;  1RQI A;  3CC9 A;  3OAC A;  3M01 A;  4LPG F;  1PS1 A;  5DJR F;  4F6X A;  4FJQ A;  5JV0 F;  3WEF A;  3AQC B;  5HN7 A;  3WCJ A;  5JV1 F;  2P1C A;  2ZEU A;  3ZL6 A;  4NG6 A;  3LJI A;  4QPF A;  4GP1 A;  3OAB B;  4QXS F;  1YYS A;  2EWG A;  5ERN A;  1V4H A;  2AET A;  3WCB A;  4KVD A;  3OAB A;  4LFE A;  4LA6 A;  3WE9 A;  1N21 A;  2QIS A;  3M00 A;  3P8L A;  1UBW A;  3EZ3 A;  5AHU B;  3APZ A;  1YYU A;  3WCI A;  3WCD A;  3OYR A;  3CP6 A;  4RXC A;  2PS5 A;  4JYX A;  3SDV A;  1N22 A;  3LGZ B;  4LZ0 A;  3LK5 A;  2O1O A;  1WL3 A;  5E8H A;  1N24 A;  3WEI A;  3SDQ A;  4E9U A;  4KK2 A;  4LZC A;  5ERM A;  5DJP F;  3LZ9 A;  4MC8 A;  1YYQ A;  3ICM A;  3ADZ A;  2Q9Y A;  3MAV A;  1WY0 A;  2Z4Z A;  4KPD A;  4XQS F;  2ZCQ A;  4PVY F;  3SAE A;  3KRA A;  5IM1 A;  2E4O A;  3V1V A;  3V66 A;  5DJV F;  3WJN A;  4P0X A;  4JZX A;  2Z4Y A;  3TFP A;  1UBV A;  3LEE A;  5HN9 A;  3VJA A;  3ACY A;  3WJO A;  3MZV A;  2Z50 A;  4LFG A;  4KQS A;  4LZ3 A;  2AEK A;  4OKM A;  5ERO A;  2E90 A;  4LUU A;  3N6K F;  4NFK F;  1ZW5 A;  3N1V F;  3ACW A;  5IK9 A;  3ID0 A;  3G4D A;  5B02 A;  4JVJ F;  2E95 A;  4DZW A;  1HX9 A;  2E8V A;  4KFA A;  5B0M A;  1KIY A;  3W7F A;  2F9K F;  4KKM A;  4DWG A;  4LOB A;  2PS6 A;  2PS8 A;  3N3D A;  1WL0 A;  3N5H F;  4LTV A;  3VJ9 A;  1WMW A;  5A0J A;  3NRI A;  4GAX A;  3TFV A;  3WEK A;  3ZMB A;  4DEM F;  5B0L A;  4K10 A;  5JV2 F;  1RQJ A;  1YHM A;  2ZCR A;  5DZ2 A;  3V1X A;  3S4J A;  5E8K A;  3PKO A;  4OMH A;  4DWB A;  1YYT A;  3Q1O A;  3WCC A;  3RYE A;  5EAT A;  3B7L A;  5IVG A;  3WCA A;  1YQ7 A;  4H5E F;  4KPJ A;  1JFG A;  4E1E A;  4LLS A;  5CG5 A;  5AFX A;  3M0G A;  2Z4V A;  3WCM A;  3LLW A;  3WJK A;  5B03 A;  3WCE A;  5B0K A;  3ACX A;  1HM4 A;  4PVX F;  4KVW A;  2Z78 A;  4XQT F;  2Z7I A;  4WK5 A;  5ER8 A;  1WL2 A;  3LMD A;  3ZMC A;  2DH4 A; 
#chains in the Genus database with same CATH homology
 3WSA A;  4F62 A;  4P0V A;  4N1Z F;  2Q58 A;  4H5C F;  3NPR A;  4GP2 A;  3NF2 A;  2F8Z F;  3DYF A;  1N20 A;  2E94 A;  5EAS A;  3LVS A;  5IN8 A;  3QKC A;  3KRA B;  4NKE A;  4RXA A;  3WCF A;  3EFQ A;  3N46 F;  3RMG A;  5KSX F;  5DW7 A;  1WL1 A;  3LGK A;  3PYB A;  5CG6 A;  1VG7 A;  2OPN A;  4NFJ F;  3WEH A;  1V4I A;  1HXA A;  3AQB B;  1N1B A;  4NFI F;  2PS7 A;  4KWD A;  4OMG A;  1HXC A;  1EZF A;  1YYR A;  4RXE A;  3WEJ A;  5ILK A;  2ONH A;  3TS7 A;  3S9V A;  2ZY1 A;  4EA0 A;  2F8C F;  5IL8 A;  3SDR A;  5B01 A;  1FPS A;  3AQ0 A;  1VG4 A;  1VG2 A;  4KVI A;  2ZCS A;  1UBY A;  5ILH A;  4L2X F;  5B0I A;  4XQR F;  3LSN A;  4JXN A;  1DGP A;  4MC3 A;  2ONG A;  3KBK A;  2AEL A;  3WSB A;  4N9U A;  5IMP A;  4DI5 A;  3DYG A;  5IKA A;  5C05 A;  5ILI A;  2E8T A;  5AYP A;  5DHK A;  1YHL A;  2RAH A;  3KRP B;  5DGM F;  2E8X A;  1RTR A;  3M02 A;  3KRO B;  3KRP A;  3P8R A;  1N1Z A;  3P5R A;  3N1W F;  3ICK A;  4LIX A;  3ICN A;  3KRO A;  1WKZ A;  3VJE A;  4JZB A;  3Q30 A;  3P41 A;  3ZCD A;  2E91 A;  5ILY A;  1YV5 A;  4EA2 A;  2FTZ A;  2Z4X A;  2E92 A;  4NKF A;  2OA6 A;  5IK6 A;  2F7M F;  3ICZ A;  3IPI A;  3WCG A;  1KIZ A;  4LXW A;  5IMI A;  1V4K A;  3IBA A;  5IMN A;  1V4E A;  3VJC A;  3KRC B;  4UMJ A;  1DI1 A;  3KB9 A;  3KRC A;  3Q2Z A;  2OPM A;  4HD1 A;  2E8W A;  3SDU A;  4DXJ A;  1YHK A;  3ASX A;  2F92 F;  5DGN F;  3NPK A;  3CKE A;  3N45 F;  4EA1 A;  5H9D A;  2ZEV A;  3KRF B;  4GA3 A;  3WC9 A;  3PDE A;  5DIQ F;  2F89 F;  5IKH A;  5IL3 A;  4P0W A;  3PH7 A;  5JUZ F;  3KRF A;  2J1P A;  3LG5 A;  3BNY A;  2OGD A;  2FOR A;  4Q23 A;  4ZQ8 A;  4DHD A;  4RXD A;  5ILZ A;  4LPH F;  5A0K A;  2E93 A;  3N3L F;  3WEG A;  4RYP A;  5E8L A;  1VG3 A;  4NUA A;  3UCA A;  1HXG A;  3M9U A;  5DGS F;  2Q9Z A;  4E9Z A;  2Z52 A;  5B00 A;  2J5C A;  4LA5 A;  3Q2Q A;  3ZOU A;  5I1U A;  3LDW A;  2Z4W A;  3VJ8 A;  1VG6 A;  3QQV A;  5JA0 F;  2J1O A;  5DHI A;  3WCL A;  4LLT A;  3N0G A;  4JXY A;  5HN8 A;  4KVY A;  2E8U A;  3N49 F;  3RYW A;  2ZCO A;  4KQU A;  3VJD A;  4OKZ A;  3PYA A;  3G4F A;  2I19 A;  2Q80 A;  3SDT A;  3DYH A;  3TFN A;  4KUX A;  3RBM A;  3BNX A;  5EAU A;  5AEL A;  3N0F A;  4RNQ A;  3EGT A;  1V4J A;  3AE0 A;  4FP4 A;  1JFA A;  2PS4 A;  1YJ4 A;  1HM7 A;  4LFV F;  2AZL A;  2AZJ A;  5IK0 A;  2Z7H A;  4KQ5 A;  3VJB A;  4MC0 A;  2AZK A;  3N5J F;  2H8O A;  1UBX A;  5HNA A;  5B0J A;  4F6V A;  1N23 A;  5ILJ A;  2F94 F;  4OGU A;  3WCH A;  4LTZ A;  4H5D F;  3P5P A;  5A0I A;  3OAC B;  2VF6 A;  5ILD A;  3TC1 A;  3LOM A;  1RQI A;  3CC9 A;  3OAC A;  3M01 A;  4LPG F;  1PS1 A;  5DJR F;  4F6X A;  4FJQ A;  5JV0 F;  3WEF A;  3AQC B;  5HN7 A;  3WCJ A;  5JV1 F;  2P1C A;  2ZEU A;  3ZL6 A;  4NG6 A;  3LJI A;  4QPF A;  4GP1 A;  3OAB B;  4QXS F;  1YYS A;  2EWG A;  5ERN A;  1V4H A;  2AET A;  3WCB A;  4KVD A;  3OAB A;  4LFE A;  4LA6 A;  3WE9 A;  1N21 A;  2QIS A;  3M00 A;  3P8L A;  1UBW A;  3EZ3 A;  5AHU B;  3APZ A;  1YYU A;  3WCI A;  3WCD A;  3OYR A;  3CP6 A;  4RXC A;  2PS5 A;  4JYX A;  3SDV A;  1N22 A;  3LGZ B;  4LZ0 A;  3LK5 A;  2O1O A;  1WL3 A;  5E8H A;  1N24 A;  3WEI A;  3SDQ A;  4E9U A;  4KK2 A;  4LZC A;  5ERM A;  5DJP F;  3LZ9 A;  4MC8 A;  1YYQ A;  3ICM A;  3ADZ A;  2Q9Y A;  3MAV A;  1WY0 A;  2Z4Z A;  4KPD A;  4XQS F;  2ZCQ A;  4PVY F;  3SAE A;  3KRA A;  5IM1 A;  2E4O A;  3V1V A;  3V66 A;  5DJV F;  3WJN A;  4P0X A;  4JZX A;  2Z4Y A;  3TFP A;  1UBV A;  3LEE A;  5HN9 A;  3VJA A;  3ACY A;  3WJO A;  3MZV A;  2Z50 A;  4LFG A;  4KQS A;  4LZ3 A;  2AEK A;  4OKM A;  5ERO A;  2E90 A;  4LUU A;  3N6K F;  4NFK F;  1ZW5 A;  3N1V F;  3ACW A;  5IK9 A;  3ID0 A;  3G4D A;  5B02 A;  4JVJ F;  2E95 A;  4DZW A;  1HX9 A;  2E8V A;  4KFA A;  5B0M A;  1KIY A;  3W7F A;  2F9K F;  4KKM A;  4DWG A;  4LOB A;  2PS6 A;  2PS8 A;  3N3D A;  1WL0 A;  3N5H F;  4LTV A;  3VJ9 A;  1WMW A;  5A0J A;  3NRI A;  4GAX A;  3TFV A;  3WEK A;  3ZMB A;  4DEM F;  5B0L A;  4K10 A;  5JV2 F;  1RQJ A;  1YHM A;  2ZCR A;  5DZ2 A;  3V1X A;  3S4J A;  5E8K A;  3PKO A;  4OMH A;  4DWB A;  1YYT A;  3Q1O A;  3WCC A;  3RYE A;  5EAT A;  3B7L A;  5IVG A;  3WCA A;  1YQ7 A;  4H5E F;  4KPJ A;  1JFG A;  4E1E A;  4LLS A;  5CG5 A;  5AFX A;  3M0G A;  2Z4V A;  3WCM A;  3LLW A;  3WJK A;  5B03 A;  3WCE A;  5B0K A;  3ACX A;  1HM4 A;  4PVX F;  4KVW A;  2Z78 A;  4XQT F;  2Z7I A;  4WK5 A;  5ER8 A;  1WL2 A;  3LMD A;  3ZMC A;  2DH4 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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