3V66A

Human squalene synthase in complex with 2-(1-{2-[(4r,6s)-8-chloro-6-(2,3-dimethoxyphenyl)-4h,6h-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetic acid
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
335
structure length
335
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Squalene synthase
publication title Discovery of novel tricyclic compounds as squalene synthase inhibitors
pubmed doi rcsb
source organism Homo sapiens
total genus 142
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3v66A00
3TFNA 1V4KA 2Z4YA 2AELA 4JZXA 2ZCRA 4NFKF 3QQVA 3LLWA 3TFPA 3N0GA 3KRCB 3AE0A 4PVXF 3KRAB 2PS8A 3DYFA 1WL3A 4KPDA 5IMIA 2P1CA 4UMJA 3N6KF 2ONHA 3WJOA 3ZMCA 2E8TA 3BNXA 3MZVA 3KRPB 3RYEA 3P8RA 5IK6A 4QXSF 2Z7IA 4H5DF 3ZCDA 4EA0A 3SAEA 2OGDA 4RXEA 4LIXA 3PDEA 3ICNA 1YYRA 2E94A 2Q80A 5AFXA 3ACYA 1HXAA 1PS1A 5HN8A 3PYBA 2Z4VA 2OPMA 3EFQA 3ASXA 3AQCB 2PS7A 4JYXA 3TC1A 3B7LA 5ILIA 3PH7A 2PS5A 3ICZA 5I1UA 4LTVA 3N49F 3P5PA 5IN8A 5DZ2A 3ACXA 5IKHA 3M02A 1HM4A 1FPSA 3KROA 3WCCA 3WCGA 2QISA 2F9KF 4LZCA 4DI5A 1HX9A 2PS6A 4Q23A 1UBVA 5H9DA 3TFVA 2OA6A 3SDUA 4LFVF 5A0IA 4P0VA 4KPJA 3LJIA 3WCHA 5ILHA 4OKZA 5B03A 3V66A 3DYGA 5HN9A 1YHKA 4LFEA 3WCAA 5EROA 3WJNA 3WSAA 1VG2A 1V4HA 2Z4WA 3LEEA 4JXNA 3P8LA 3WEHA 5JA0F 3RYWA 3M01A 5AHUB 5ER8A 2E8XA 3ICMA 4LA6A 3M00A 5CG6A 2I19A 3KROB 3KBKA 1WL2A 2PS4A 3WEIA 1WKZA 2Z78A 3LOMA 2ZCOA 4NKFA 4GAXA 3M0GA 3ICKA 4NUAA 2E8VA 3G4DA 3N45F 3WCIA 3NRIA 4OKMA 1VG7A 4KVYA 3TS7A 3LG5A 4LLTA 2Z4ZA 3LSNA 5IL8A 4LTZA 3Q2ZA 5DHKA 5DW7A 2E92A 5DIQF 3ZMBA 4RYPA 3RMGA 4DWGA 3ADZA 1WL0A 4GP2A 1V4EA 3PYAA 4F62A 3WCLA 2ONGA 1UBWA 4OMGA 2FORA 5DJPF 2ZCSA 4LPHF 2E8UA 4KQUA 5EASA 3N1VF 3V1VA 3EGTA 3KB9A 3G4FA 5DGSF 2ZCQA 2ZY1A 4EA2A 1YYTA 4KK2A 2ZEUA 2RAHA 4RXDA 4DHDA 3SDQA 3DYHA 4LZ3A 3P5RA 3S4JA 5B02A 4FP4A 4JXYA 1YYUA 3N3LF 4NG6A 3LDWA 3NPRA 4LXWA 5ILDA 5B0LA 1VG3A 3KRFA 3WCFA 2EWGA 3VJ8A 3LGZB 4E1EA 4DXJA 3VJEA 4OGUA 1ZW5A 3VJDA 2E93A 4E9ZA 4JVJF 2ZEVA 3Q2QA 1UBXA 5KSXF 5DGMF 5B0MA 3PKOA 4XQRF 1DGPA 1YJ4A 4LOBA 3LMDA 4LFGA 5A0KA 2OPNA 4NFJF 5B01A 4LPGF 5E8KA 3WCMA 1HXCA 2E4OA 5IL3A 4P0WA 4FJQA 4MC3A 3UCAA 3BNYA 1HXGA 3KRFB 1N23A 3M9UA 3ACWA 1YQ7A 1YHMA 2O1OA 3NF2A 2F94F 5HNAA 4K10A 3CC9A 4LZ0A 3VJCA 3IPIA 1RQIA 4GP1A 3WEJA 3W7FA 3ZL6A 4KQSA 1N21A 3LZ9A 3Q1OA 4DEMF 3OACA 1HM7A 2FTZA 1N1BA 5HN7A 5A0JA 1YHLA 2E8WA 2Z7HA 4RXAA 3N0FA 5DGNF 1KIZA 4GA3A 4RXCA 1WMWA 4PVYF 5DHIA 3CP6A 4LA5A 3Q30A 4H5CF 4KQ5A 4KUXA 3WCBA 3N5JF 5JV2F 1VG4A 2Q9YA 3P41A 4KVIA 3APZA 4KWDA 3MAVA 2Z52A 5E8LA 5EAUA 3N1WF 5B0IA 4H5EF 2E90A 1KIYA 2Q9ZA 3OACB 3IBAA 4KKMA 3WJKA 5ILZA 3LVSA 3WEGA 5JV1F 5IMNA 3NPKA 3WC9A 4LUUA 2AZLA 3OABA 5EATA 3RBMA 3SDRA 2F8ZF 3WE9A 2DH4A 4N1ZF 3EZ3A 5E8HA 1N22A 3S9VA 1UBYA 1JFGA 3WCEA 2H8OA 4KFAA 5ERNA 4F6VA 5DJVF 2AEKA 3VJBA 1V4JA 3WEKA 5ERMA 1RTRA 3N5HF 4RNQA 5IMPA 5IK0A 4KVDA 4WK5A 2AZJA 2Q58A 3WSBA 1EZFA 3SDTA 3AQ0A 3CKEA 3LGKA 1V4IA 3AQBB 4F6XA 2Z4XA 5B0KA 5ILYA 4MC0A 4KVWA 2AETA 1VG6A 3VJ9A 4N9UA 5IKAA 5JV0F 3WCJA 3QKCA 4P0XA 3OABB 5CG5A 5AELA 5B00A 2Z50A 3SDVA 4L2XF 2F8CF 1JFAA 4NKEA 2VF6A 4JZBA 5ILKA 4XQTF 5C05A 5IK9A 4NFIF 5B0JA 4DWBA 3VJAA 3WEFA 3KRCA 5DJRF 2F7MF 3N3DA 2AZKA 3KRAA 1N20A 1WY0A 4QPFA 1N1ZA 4ZQ8A 4EA1A 5JUZF 5IM1A 3WCDA 1YV5A 3ZOUA 2F89F 5ILJA 1YYQA 3OYRA 4HD1A 4OMHA 1RQJA 3KRPA 1WL1A 2J1PA 4DZWA 4MC8A 2F92F 5AYPA 4XQSF 3N46F 5IVGA 1YYSA 1N24A 1DI1A 2E95A 3ID0A 2E91A 2J5CA 3V1XA 4LLSA 4E9UA 2J1OA 3LK5A
chains in the Genus database with same CATH superfamily
3TFNA 1V4KA 2Z4YA 2AELA 4JZXA 2ZCRA 4NFKF 3QQVA 3LLWA 3TFPA 3N0GA 3KRCB 3AE0A 4PVXF 3KRAB 2PS8A 3DYFA 1WL3A 4KPDA 5IMIA 2P1CA 4UMJA 3N6KF 2ONHA 3WJOA 3ZMCA 2E8TA 3BNXA 3MZVA 3KRPB 3RYEA 3P8RA 5IK6A 4QXSF 2Z7IA 4H5DF 3ZCDA 4EA0A 3SAEA 2OGDA 4RXEA 4LIXA 3PDEA 3ICNA 1YYRA 2E94A 2Q80A 5AFXA 3ACYA 1HXAA 1PS1A 5HN8A 3PYBA 2Z4VA 2OPMA 3EFQA 3ASXA 3AQCB 2PS7A 4JYXA 3TC1A 3B7LA 5ILIA 3PH7A 2PS5A 3ICZA 5I1UA 4LTVA 3N49F 3P5PA 5IN8A 5DZ2A 3ACXA 5IKHA 3M02A 1HM4A 1FPSA 3KROA 3WCCA 3WCGA 2QISA 2F9KF 4LZCA 4DI5A 1HX9A 2PS6A 4Q23A 1UBVA 5H9DA 3TFVA 2OA6A 3SDUA 4LFVF 5A0IA 4P0VA 4KPJA 3LJIA 3WCHA 5ILHA 4OKZA 5B03A 3V66A 3DYGA 5HN9A 1YHKA 4LFEA 3WCAA 5EROA 3WJNA 3WSAA 1VG2A 1V4HA 2Z4WA 3LEEA 4JXNA 3P8LA 3WEHA 5JA0F 3RYWA 3M01A 5AHUB 5ER8A 2E8XA 3ICMA 4LA6A 3M00A 5CG6A 2I19A 3KROB 3KBKA 1WL2A 2PS4A 3WEIA 1WKZA 2Z78A 3LOMA 2ZCOA 4NKFA 4GAXA 3M0GA 3ICKA 4NUAA 2E8VA 3G4DA 3N45F 3WCIA 3NRIA 4OKMA 1VG7A 4KVYA 3TS7A 3LG5A 4LLTA 2Z4ZA 3LSNA 5IL8A 4LTZA 3Q2ZA 5DHKA 5DW7A 2E92A 5DIQF 3ZMBA 4RYPA 3RMGA 4DWGA 3ADZA 1WL0A 4GP2A 1V4EA 3PYAA 4F62A 3WCLA 2ONGA 1UBWA 4OMGA 2FORA 5DJPF 2ZCSA 4LPHF 2E8UA 4KQUA 5EASA 3N1VF 3V1VA 3EGTA 3KB9A 3G4FA 5DGSF 2ZCQA 2ZY1A 4EA2A 1YYTA 4KK2A 2ZEUA 2RAHA 4RXDA 4DHDA 3SDQA 3DYHA 4LZ3A 3P5RA 3S4JA 5B02A 4FP4A 4JXYA 1YYUA 3N3LF 4NG6A 3LDWA 3NPRA 4LXWA 5ILDA 5B0LA 1VG3A 3KRFA 3WCFA 2EWGA 3VJ8A 3LGZB 4E1EA 4DXJA 3VJEA 4OGUA 1ZW5A 3VJDA 2E93A 4E9ZA 4JVJF 2ZEVA 3Q2QA 1UBXA 5KSXF 5DGMF 5B0MA 3PKOA 4XQRF 1DGPA 1YJ4A 4LOBA 3LMDA 4LFGA 5A0KA 2OPNA 4NFJF 5B01A 4LPGF 5E8KA 3WCMA 1HXCA 2E4OA 5IL3A 4P0WA 4FJQA 4MC3A 3UCAA 3BNYA 1HXGA 3KRFB 1N23A 3M9UA 3ACWA 1YQ7A 1YHMA 2O1OA 3NF2A 2F94F 5HNAA 4K10A 3CC9A 4LZ0A 3VJCA 3IPIA 1RQIA 4GP1A 3WEJA 3W7FA 3ZL6A 4KQSA 1N21A 3LZ9A 3Q1OA 4DEMF 3OACA 1HM7A 2FTZA 1N1BA 5HN7A 5A0JA 1YHLA 2E8WA 2Z7HA 4RXAA 3N0FA 5DGNF 1KIZA 4GA3A 4RXCA 1WMWA 4PVYF 5DHIA 3CP6A 4LA5A 3Q30A 4H5CF 4KQ5A 4KUXA 3WCBA 3N5JF 5JV2F 1VG4A 2Q9YA 3P41A 4KVIA 3APZA 4KWDA 3MAVA 2Z52A 5E8LA 5EAUA 3N1WF 5B0IA 4H5EF 2E90A 1KIYA 2Q9ZA 3OACB 3IBAA 4KKMA 3WJKA 5ILZA 3LVSA 3WEGA 5JV1F 5IMNA 3NPKA 3WC9A 4LUUA 2AZLA 3OABA 5EATA 3RBMA 3SDRA 2F8ZF 3WE9A 2DH4A 4N1ZF 3EZ3A 5E8HA 1N22A 3S9VA 1UBYA 1JFGA 3WCEA 2H8OA 4KFAA 5ERNA 4F6VA 5DJVF 2AEKA 3VJBA 1V4JA 3WEKA 5ERMA 1RTRA 3N5HF 4RNQA 5IMPA 5IK0A 4KVDA 4WK5A 2AZJA 2Q58A 3WSBA 1EZFA 3SDTA 3AQ0A 3CKEA 3LGKA 1V4IA 3AQBB 4F6XA 2Z4XA 5B0KA 5ILYA 4MC0A 4KVWA 2AETA 1VG6A 3VJ9A 4N9UA 5IKAA 5JV0F 3WCJA 3QKCA 4P0XA 3OABB 5CG5A 5AELA 5B00A 2Z50A 3SDVA 4L2XF 2F8CF 1JFAA 4NKEA 2VF6A 4JZBA 5ILKA 4XQTF 5C05A 5IK9A 4NFIF 5B0JA 4DWBA 3VJAA 3WEFA 3KRCA 5DJRF 2F7MF 3N3DA 2AZKA 3KRAA 1N20A 1WY0A 4QPFA 1N1ZA 4ZQ8A 4EA1A 5JUZF 5IM1A 3WCDA 1YV5A 3ZOUA 2F89F 5ILJA 1YYQA 3OYRA 4HD1A 4OMHA 1RQJA 3KRPA 1WL1A 2J1PA 4DZWA 4MC8A 2F92F 5AYPA 4XQSF 3N46F 5IVGA 1YYSA 1N24A 1DI1A 2E95A 3ID0A 2E91A 2J5CA 3V1XA 4LLSA 4E9UA 2J1OA 3LK5A
chains in the Genus database with same CATH topology
3TFNA 1V4KA 2Z4YA 2AELA 4JZXA 2ZCRA 4NFKF 3QQVA 3LLWA 3TFPA 3N0GA 3KRCB 3AE0A 4PVXF 3KRAB 2PS8A 3DYFA 1WL3A 4KPDA 5IMIA 2P1CA 4UMJA 3N6KF 2ONHA 3WJOA 3ZMCA 2E8TA 3BNXA 3MZVA 3KRPB 3RYEA 3P8RA 5IK6A 4QXSF 2Z7IA 4H5DF 3ZCDA 4EA0A 3SAEA 2OGDA 4RXEA 4LIXA 3PDEA 3ICNA 1YYRA 2E94A 2Q80A 5AFXA 3ACYA 1HXAA 1PS1A 5HN8A 3PYBA 2Z4VA 2OPMA 3EFQA 3ASXA 3AQCB 2PS7A 4JYXA 3TC1A 3B7LA 5ILIA 3PH7A 2PS5A 3ICZA 5I1UA 4LTVA 3N49F 3P5PA 5IN8A 5DZ2A 3ACXA 5IKHA 3M02A 1HM4A 1FPSA 3KROA 3WCCA 3WCGA 2QISA 2F9KF 4LZCA 4DI5A 1HX9A 2PS6A 4Q23A 1UBVA 5H9DA 3TFVA 2OA6A 3SDUA 4LFVF 5A0IA 4P0VA 4KPJA 3LJIA 3WCHA 5ILHA 4OKZA 5B03A 3V66A 3DYGA 5HN9A 1YHKA 4LFEA 3WCAA 5EROA 3WJNA 3WSAA 1VG2A 1V4HA 2Z4WA 3LEEA 4JXNA 3P8LA 3WEHA 5JA0F 3RYWA 3M01A 5AHUB 5ER8A 2E8XA 3ICMA 4LA6A 3M00A 5CG6A 2I19A 3KROB 3KBKA 1WL2A 2PS4A 3WEIA 1WKZA 2Z78A 3LOMA 2ZCOA 4NKFA 4GAXA 3M0GA 3ICKA 4NUAA 2E8VA 3G4DA 3N45F 3WCIA 3NRIA 4OKMA 1VG7A 4KVYA 3TS7A 3LG5A 4LLTA 2Z4ZA 3LSNA 5IL8A 4LTZA 3Q2ZA 5DHKA 5DW7A 2E92A 5DIQF 3ZMBA 4RYPA 3RMGA 4DWGA 3ADZA 1WL0A 4GP2A 1V4EA 3PYAA 4F62A 3WCLA 2ONGA 1UBWA 4OMGA 2FORA 5DJPF 2ZCSA 4LPHF 2E8UA 4KQUA 5EASA 3N1VF 3V1VA 3EGTA 3KB9A 3G4FA 5DGSF 2ZCQA 2ZY1A 4EA2A 1YYTA 4KK2A 2ZEUA 2RAHA 4RXDA 4DHDA 3SDQA 3DYHA 4LZ3A 3P5RA 3S4JA 5B02A 4FP4A 4JXYA 1YYUA 3N3LF 4NG6A 3LDWA 3NPRA 4LXWA 5ILDA 5B0LA 1VG3A 3KRFA 3WCFA 2EWGA 3VJ8A 3LGZB 4E1EA 4DXJA 3VJEA 4OGUA 1ZW5A 3VJDA 2E93A 4E9ZA 4JVJF 2ZEVA 3Q2QA 1UBXA 5KSXF 5DGMF 5B0MA 3PKOA 4XQRF 1DGPA 1YJ4A 4LOBA 3LMDA 4LFGA 5A0KA 2OPNA 4NFJF 5B01A 4LPGF 5E8KA 3WCMA 1HXCA 2E4OA 5IL3A 4P0WA 4FJQA 4MC3A 3UCAA 3BNYA 1HXGA 3KRFB 1N23A 3M9UA 3ACWA 1YQ7A 1YHMA 2O1OA 3NF2A 2F94F 5HNAA 4K10A 3CC9A 4LZ0A 3VJCA 3IPIA 1RQIA 4GP1A 3WEJA 3W7FA 3ZL6A 4KQSA 1N21A 3LZ9A 3Q1OA 4DEMF 3OACA 1HM7A 2FTZA 1N1BA 5HN7A 5A0JA 1YHLA 2E8WA 2Z7HA 4RXAA 3N0FA 5DGNF 1KIZA 4GA3A 4RXCA 1WMWA 4PVYF 5DHIA 3CP6A 4LA5A 3Q30A 4H5CF 4KQ5A 4KUXA 3WCBA 3N5JF 5JV2F 1VG4A 2Q9YA 3P41A 4KVIA 3APZA 4KWDA 3MAVA 2Z52A 5E8LA 5EAUA 3N1WF 5B0IA 4H5EF 2E90A 1KIYA 2Q9ZA 3OACB 3IBAA 4KKMA 3WJKA 5ILZA 3LVSA 3WEGA 5JV1F 5IMNA 3NPKA 3WC9A 4LUUA 2AZLA 3OABA 5EATA 3RBMA 3SDRA 2F8ZF 3WE9A 2DH4A 4N1ZF 3EZ3A 5E8HA 1N22A 3S9VA 1UBYA 1JFGA 3WCEA 2H8OA 4KFAA 5ERNA 4F6VA 5DJVF 2AEKA 3VJBA 1V4JA 3WEKA 5ERMA 1RTRA 3N5HF 4RNQA 5IMPA 5IK0A 4KVDA 4WK5A 2AZJA 2Q58A 3WSBA 1EZFA 3SDTA 3AQ0A 3CKEA 3LGKA 1V4IA 3AQBB 4F6XA 2Z4XA 5B0KA 5ILYA 4MC0A 4KVWA 2AETA 1VG6A 3VJ9A 4N9UA 5IKAA 5JV0F 3WCJA 3QKCA 4P0XA 3OABB 5CG5A 5AELA 5B00A 2Z50A 3SDVA 4L2XF 2F8CF 1JFAA 4NKEA 2VF6A 4JZBA 5ILKA 4XQTF 5C05A 5IK9A 4NFIF 5B0JA 4DWBA 3VJAA 3WEFA 3KRCA 5DJRF 2F7MF 3N3DA 2AZKA 3KRAA 1N20A 1WY0A 4QPFA 1N1ZA 4ZQ8A 4EA1A 5JUZF 5IM1A 3WCDA 1YV5A 3ZOUA 2F89F 5ILJA 1YYQA 3OYRA 4HD1A 4OMHA 1RQJA 3KRPA 1WL1A 2J1PA 4DZWA 4MC8A 2F92F 5AYPA 4XQSF 3N46F 5IVGA 1YYSA 1N24A 1DI1A 2E95A 3ID0A 2E91A 2J5CA 3V1XA 4LLSA 4E9UA 2J1OA 3LK5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TFN A;  1V4K A;  2Z4Y A;  2AEL A;  4JZX A;  2ZCR A;  4NFK F;  3QQV A;  3LLW A;  3TFP A;  3N0G A;  3KRC B;  3AE0 A;  4PVX F;  3KRA B;  2PS8 A;  3DYF A;  1WL3 A;  4KPD A;  5IMI A;  2P1C A;  4UMJ A;  3N6K F;  2ONH A;  3WJO A;  3ZMC A;  2E8T A;  3BNX A;  3MZV A;  3KRP B;  3RYE A;  3P8R A;  5IK6 A;  4QXS F;  2Z7I A;  4H5D F;  3ZCD A;  4EA0 A;  3SAE A;  2OGD A;  4RXE A;  4LIX A;  3PDE A;  3ICN A;  1YYR A;  2E94 A;  2Q80 A;  5AFX A;  3ACY A;  1HXA A;  1PS1 A;  5HN8 A;  3PYB A;  2Z4V A;  2OPM A;  3EFQ A;  3ASX A;  3AQC B;  2PS7 A;  4JYX A;  3TC1 A;  3B7L A;  5ILI A;  3PH7 A;  2PS5 A;  3ICZ A;  5I1U A;  4LTV A;  3N49 F;  3P5P A;  5IN8 A;  5DZ2 A;  3ACX A;  5IKH A;  3M02 A;  1HM4 A;  1FPS A;  3KRO A;  3WCC A;  3WCG A;  2QIS A;  2F9K F;  4LZC A;  4DI5 A;  1HX9 A;  2PS6 A;  4Q23 A;  1UBV A;  5H9D A;  3TFV A;  2OA6 A;  3SDU A;  4LFV F;  5A0I A;  4P0V A;  4KPJ A;  3LJI A;  3WCH A;  5ILH A;  4OKZ A;  5B03 A;  3V66 A;  3DYG A;  5HN9 A;  1YHK A;  4LFE A;  3WCA A;  5ERO A;  3WJN A;  3WSA A;  1VG2 A;  1V4H A;  2Z4W A;  3LEE A;  4JXN A;  3P8L A;  3WEH A;  5JA0 F;  3RYW A;  3M01 A;  5AHU B;  5ER8 A;  2E8X A;  3ICM A;  4LA6 A;  3M00 A;  5CG6 A;  2I19 A;  3KRO B;  3KBK A;  1WL2 A;  2PS4 A;  3WEI A;  1WKZ A;  2Z78 A;  3LOM A;  2ZCO A;  4NKF A;  4GAX A;  3M0G A;  3ICK A;  4NUA A;  2E8V A;  3G4D A;  3N45 F;  3WCI A;  3NRI A;  4OKM A;  1VG7 A;  4KVY A;  3TS7 A;  3LG5 A;  4LLT A;  2Z4Z A;  3LSN A;  5IL8 A;  4LTZ A;  3Q2Z A;  5DHK A;  5DW7 A;  2E92 A;  5DIQ F;  3ZMB A;  4RYP A;  3RMG A;  4DWG A;  3ADZ A;  1WL0 A;  4GP2 A;  1V4E A;  3PYA A;  4F62 A;  3WCL A;  2ONG A;  1UBW A;  4OMG A;  2FOR A;  5DJP F;  2ZCS A;  4LPH F;  2E8U A;  4KQU A;  5EAS A;  3N1V F;  3V1V A;  3EGT A;  3KB9 A;  3G4F A;  5DGS F;  2ZCQ A;  2ZY1 A;  4EA2 A;  1YYT A;  4KK2 A;  2ZEU A;  2RAH A;  4RXD A;  4DHD A;  3SDQ A;  3DYH A;  4LZ3 A;  3P5R A;  3S4J A;  5B02 A;  4FP4 A;  4JXY A;  1YYU A;  3N3L F;  4NG6 A;  3LDW A;  3NPR A;  4LXW A;  5ILD A;  5B0L A;  1VG3 A;  3KRF A;  3WCF A;  2EWG A;  3VJ8 A;  3LGZ B;  4E1E A;  4DXJ A;  3VJE A;  4OGU A;  1ZW5 A;  3VJD A;  2E93 A;  4E9Z A;  4JVJ F;  2ZEV A;  3Q2Q A;  1UBX A;  5KSX F;  5DGM F;  5B0M A;  3PKO A;  4XQR F;  1DGP A;  1YJ4 A;  4LOB A;  3LMD A;  4LFG A;  5A0K A;  2OPN A;  4NFJ F;  5B01 A;  4LPG F;  5E8K A;  3WCM A;  1HXC A;  2E4O A;  5IL3 A;  4P0W A;  4FJQ A;  4MC3 A;  3UCA A;  3BNY A;  1HXG A;  3KRF B;  1N23 A;  3M9U A;  3ACW A;  1YQ7 A;  1YHM A;  2O1O A;  3NF2 A;  2F94 F;  5HNA A;  4K10 A;  3CC9 A;  4LZ0 A;  3VJC A;  3IPI A;  1RQI A;  4GP1 A;  3WEJ A;  3W7F A;  3ZL6 A;  4KQS A;  1N21 A;  3LZ9 A;  3Q1O A;  4DEM F;  3OAC A;  1HM7 A;  2FTZ A;  1N1B A;  5HN7 A;  5A0J A;  1YHL A;  2E8W A;  2Z7H A;  4RXA A;  3N0F A;  5DGN F;  1KIZ A;  4GA3 A;  4RXC A;  1WMW A;  4PVY F;  5DHI A;  3CP6 A;  4LA5 A;  3Q30 A;  4H5C F;  4KQ5 A;  4KUX A;  3WCB A;  3N5J F;  5JV2 F;  1VG4 A;  2Q9Y A;  3P41 A;  4KVI A;  3APZ A;  4KWD A;  3MAV A;  2Z52 A;  5E8L A;  5EAU A;  3N1W F;  5B0I A;  4H5E F;  2E90 A;  1KIY A;  2Q9Z A;  3OAC B;  3IBA A;  4KKM A;  3WJK A;  5ILZ A;  3LVS A;  3WEG A;  5JV1 F;  5IMN A;  3NPK A;  3WC9 A;  4LUU A;  2AZL A;  3OAB A;  5EAT A;  3RBM A;  3SDR A;  2F8Z F;  3WE9 A;  2DH4 A;  4N1Z F;  3EZ3 A;  5E8H A;  1N22 A;  3S9V A;  1UBY A;  1JFG A;  3WCE A;  2H8O A;  4KFA A;  5ERN A;  4F6V A;  5DJV F;  2AEK A;  3VJB A;  1V4J A;  3WEK A;  5ERM A;  1RTR A;  3N5H F;  4RNQ A;  5IMP A;  5IK0 A;  4KVD A;  4WK5 A;  2AZJ A;  2Q58 A;  3WSB A;  1EZF A;  3SDT A;  3AQ0 A;  3CKE A;  3LGK A;  1V4I A;  3AQB B;  4F6X A;  2Z4X A;  5B0K A;  5ILY A;  4MC0 A;  4KVW A;  2AET A;  1VG6 A;  3VJ9 A;  4N9U A;  5IKA A;  5JV0 F;  3WCJ A;  3QKC A;  4P0X A;  3OAB B;  5CG5 A;  5AEL A;  5B00 A;  2Z50 A;  3SDV A;  4L2X F;  2F8C F;  1JFA A;  4NKE A;  2VF6 A;  4JZB A;  5ILK A;  4XQT F;  5C05 A;  5IK9 A;  4NFI F;  5B0J A;  4DWB A;  3VJA A;  3WEF A;  3KRC A;  5DJR F;  2F7M F;  3N3D A;  2AZK A;  3KRA A;  1N20 A;  1WY0 A;  4QPF A;  1N1Z A;  4ZQ8 A;  4EA1 A;  5JUZ F;  5IM1 A;  3WCD A;  1YV5 A;  3ZOU A;  2F89 F;  5ILJ A;  1YYQ A;  3OYR A;  4HD1 A;  4OMH A;  1RQJ A;  3KRP A;  1WL1 A;  2J1P A;  4DZW A;  4MC8 A;  2F92 F;  5AYP A;  4XQS F;  3N46 F;  5IVG A;  1YYS A;  1N24 A;  1DI1 A;  2E95 A;  3ID0 A;  2E91 A;  2J5C A;  3V1X A;  4LLS A;  4E9U A;  2J1O A;  3LK5 A; 
#chains in the Genus database with same CATH topology
 3TFN A;  1V4K A;  2Z4Y A;  2AEL A;  4JZX A;  2ZCR A;  4NFK F;  3QQV A;  3LLW A;  3TFP A;  3N0G A;  3KRC B;  3AE0 A;  4PVX F;  3KRA B;  2PS8 A;  3DYF A;  1WL3 A;  4KPD A;  5IMI A;  2P1C A;  4UMJ A;  3N6K F;  2ONH A;  3WJO A;  3ZMC A;  2E8T A;  3BNX A;  3MZV A;  3KRP B;  3RYE A;  3P8R A;  5IK6 A;  4QXS F;  2Z7I A;  4H5D F;  3ZCD A;  4EA0 A;  3SAE A;  2OGD A;  4RXE A;  4LIX A;  3PDE A;  3ICN A;  1YYR A;  2E94 A;  2Q80 A;  5AFX A;  3ACY A;  1HXA A;  1PS1 A;  5HN8 A;  3PYB A;  2Z4V A;  2OPM A;  3EFQ A;  3ASX A;  3AQC B;  2PS7 A;  4JYX A;  3TC1 A;  3B7L A;  5ILI A;  3PH7 A;  2PS5 A;  3ICZ A;  5I1U A;  4LTV A;  3N49 F;  3P5P A;  5IN8 A;  5DZ2 A;  3ACX A;  5IKH A;  3M02 A;  1HM4 A;  1FPS A;  3KRO A;  3WCC A;  3WCG A;  2QIS A;  2F9K F;  4LZC A;  4DI5 A;  1HX9 A;  2PS6 A;  4Q23 A;  1UBV A;  5H9D A;  3TFV A;  2OA6 A;  3SDU A;  4LFV F;  5A0I A;  4P0V A;  4KPJ A;  3LJI A;  3WCH A;  5ILH A;  4OKZ A;  5B03 A;  3V66 A;  3DYG A;  5HN9 A;  1YHK A;  4LFE A;  3WCA A;  5ERO A;  3WJN A;  3WSA A;  1VG2 A;  1V4H A;  2Z4W A;  3LEE A;  4JXN A;  3P8L A;  3WEH A;  5JA0 F;  3RYW A;  3M01 A;  5AHU B;  5ER8 A;  2E8X A;  3ICM A;  4LA6 A;  3M00 A;  5CG6 A;  2I19 A;  3KRO B;  3KBK A;  1WL2 A;  2PS4 A;  3WEI A;  1WKZ A;  2Z78 A;  3LOM A;  2ZCO A;  4NKF A;  4GAX A;  3M0G A;  3ICK A;  4NUA A;  2E8V A;  3G4D A;  3N45 F;  3WCI A;  3NRI A;  4OKM A;  1VG7 A;  4KVY A;  3TS7 A;  3LG5 A;  4LLT A;  2Z4Z A;  3LSN A;  5IL8 A;  4LTZ A;  3Q2Z A;  5DHK A;  5DW7 A;  2E92 A;  5DIQ F;  3ZMB A;  4RYP A;  3RMG A;  4DWG A;  3ADZ A;  1WL0 A;  4GP2 A;  1V4E A;  3PYA A;  4F62 A;  3WCL A;  2ONG A;  1UBW A;  4OMG A;  2FOR A;  5DJP F;  2ZCS A;  4LPH F;  2E8U A;  4KQU A;  5EAS A;  3N1V F;  3V1V A;  3EGT A;  3KB9 A;  3G4F A;  5DGS F;  2ZCQ A;  2ZY1 A;  4EA2 A;  1YYT A;  4KK2 A;  2ZEU A;  2RAH A;  4RXD A;  4DHD A;  3SDQ A;  3DYH A;  4LZ3 A;  3P5R A;  3S4J A;  5B02 A;  4FP4 A;  4JXY A;  1YYU A;  3N3L F;  4NG6 A;  3LDW A;  3NPR A;  4LXW A;  5ILD A;  5B0L A;  1VG3 A;  3KRF A;  3WCF A;  2EWG A;  3VJ8 A;  3LGZ B;  4E1E A;  4DXJ A;  3VJE A;  4OGU A;  1ZW5 A;  3VJD A;  2E93 A;  4E9Z A;  4JVJ F;  2ZEV A;  3Q2Q A;  1UBX A;  5KSX F;  5DGM F;  5B0M A;  3PKO A;  4XQR F;  1DGP A;  1YJ4 A;  4LOB A;  3LMD A;  4LFG A;  5A0K A;  2OPN A;  4NFJ F;  5B01 A;  4LPG F;  5E8K A;  3WCM A;  1HXC A;  2E4O A;  5IL3 A;  4P0W A;  4FJQ A;  4MC3 A;  3UCA A;  3BNY A;  1HXG A;  3KRF B;  1N23 A;  3M9U A;  3ACW A;  1YQ7 A;  1YHM A;  2O1O A;  3NF2 A;  2F94 F;  5HNA A;  4K10 A;  3CC9 A;  4LZ0 A;  3VJC A;  3IPI A;  1RQI A;  4GP1 A;  3WEJ A;  3W7F A;  3ZL6 A;  4KQS A;  1N21 A;  3LZ9 A;  3Q1O A;  4DEM F;  3OAC A;  1HM7 A;  2FTZ A;  1N1B A;  5HN7 A;  5A0J A;  1YHL A;  2E8W A;  2Z7H A;  4RXA A;  3N0F A;  5DGN F;  1KIZ A;  4GA3 A;  4RXC A;  1WMW A;  4PVY F;  5DHI A;  3CP6 A;  4LA5 A;  3Q30 A;  4H5C F;  4KQ5 A;  4KUX A;  3WCB A;  3N5J F;  5JV2 F;  1VG4 A;  2Q9Y A;  3P41 A;  4KVI A;  3APZ A;  4KWD A;  3MAV A;  2Z52 A;  5E8L A;  5EAU A;  3N1W F;  5B0I A;  4H5E F;  2E90 A;  1KIY A;  2Q9Z A;  3OAC B;  3IBA A;  4KKM A;  3WJK A;  5ILZ A;  3LVS A;  3WEG A;  5JV1 F;  5IMN A;  3NPK A;  3WC9 A;  4LUU A;  2AZL A;  3OAB A;  5EAT A;  3RBM A;  3SDR A;  2F8Z F;  3WE9 A;  2DH4 A;  4N1Z F;  3EZ3 A;  5E8H A;  1N22 A;  3S9V A;  1UBY A;  1JFG A;  3WCE A;  2H8O A;  4KFA A;  5ERN A;  4F6V A;  5DJV F;  2AEK A;  3VJB A;  1V4J A;  3WEK A;  5ERM A;  1RTR A;  3N5H F;  4RNQ A;  5IMP A;  5IK0 A;  4KVD A;  4WK5 A;  2AZJ A;  2Q58 A;  3WSB A;  1EZF A;  3SDT A;  3AQ0 A;  3CKE A;  3LGK A;  1V4I A;  3AQB B;  4F6X A;  2Z4X A;  5B0K A;  5ILY A;  4MC0 A;  4KVW A;  2AET A;  1VG6 A;  3VJ9 A;  4N9U A;  5IKA A;  5JV0 F;  3WCJ A;  3QKC A;  4P0X A;  3OAB B;  5CG5 A;  5AEL A;  5B00 A;  2Z50 A;  3SDV A;  4L2X F;  2F8C F;  1JFA A;  4NKE A;  2VF6 A;  4JZB A;  5ILK A;  4XQT F;  5C05 A;  5IK9 A;  4NFI F;  5B0J A;  4DWB A;  3VJA A;  3WEF A;  3KRC A;  5DJR F;  2F7M F;  3N3D A;  2AZK A;  3KRA A;  1N20 A;  1WY0 A;  4QPF A;  1N1Z A;  4ZQ8 A;  4EA1 A;  5JUZ F;  5IM1 A;  3WCD A;  1YV5 A;  3ZOU A;  2F89 F;  5ILJ A;  1YYQ A;  3OYR A;  4HD1 A;  4OMH A;  1RQJ A;  3KRP A;  1WL1 A;  2J1P A;  4DZW A;  4MC8 A;  2F92 F;  5AYP A;  4XQS F;  3N46 F;  5IVG A;  1YYS A;  1N24 A;  1DI1 A;  2E95 A;  3ID0 A;  2E91 A;  2J5C A;  3V1X A;  4LLS A;  4E9U A;  2J1O A;  3LK5 A; 
#chains in the Genus database with same CATH homology
 3TFN A;  1V4K A;  2Z4Y A;  2AEL A;  4JZX A;  2ZCR A;  4NFK F;  3QQV A;  3LLW A;  3TFP A;  3N0G A;  3KRC B;  3AE0 A;  4PVX F;  3KRA B;  2PS8 A;  3DYF A;  1WL3 A;  4KPD A;  5IMI A;  2P1C A;  4UMJ A;  3N6K F;  2ONH A;  3WJO A;  3ZMC A;  2E8T A;  3BNX A;  3MZV A;  3KRP B;  3RYE A;  3P8R A;  5IK6 A;  4QXS F;  2Z7I A;  4H5D F;  3ZCD A;  4EA0 A;  3SAE A;  2OGD A;  4RXE A;  4LIX A;  3PDE A;  3ICN A;  1YYR A;  2E94 A;  2Q80 A;  5AFX A;  3ACY A;  1HXA A;  1PS1 A;  5HN8 A;  3PYB A;  2Z4V A;  2OPM A;  3EFQ A;  3ASX A;  3AQC B;  2PS7 A;  4JYX A;  3TC1 A;  3B7L A;  5ILI A;  3PH7 A;  2PS5 A;  3ICZ A;  5I1U A;  4LTV A;  3N49 F;  3P5P A;  5IN8 A;  5DZ2 A;  3ACX A;  5IKH A;  3M02 A;  1HM4 A;  1FPS A;  3KRO A;  3WCC A;  3WCG A;  2QIS A;  2F9K F;  4LZC A;  4DI5 A;  1HX9 A;  2PS6 A;  4Q23 A;  1UBV A;  5H9D A;  3TFV A;  2OA6 A;  3SDU A;  4LFV F;  5A0I A;  4P0V A;  4KPJ A;  3LJI A;  3WCH A;  5ILH A;  4OKZ A;  5B03 A;  3V66 A;  3DYG A;  5HN9 A;  1YHK A;  4LFE A;  3WCA A;  5ERO A;  3WJN A;  3WSA A;  1VG2 A;  1V4H A;  2Z4W A;  3LEE A;  4JXN A;  3P8L A;  3WEH A;  5JA0 F;  3RYW A;  3M01 A;  5AHU B;  5ER8 A;  2E8X A;  3ICM A;  4LA6 A;  3M00 A;  5CG6 A;  2I19 A;  3KRO B;  3KBK A;  1WL2 A;  2PS4 A;  3WEI A;  1WKZ A;  2Z78 A;  3LOM A;  2ZCO A;  4NKF A;  4GAX A;  3M0G A;  3ICK A;  4NUA A;  2E8V A;  3G4D A;  3N45 F;  3WCI A;  3NRI A;  4OKM A;  1VG7 A;  4KVY A;  3TS7 A;  3LG5 A;  4LLT A;  2Z4Z A;  3LSN A;  5IL8 A;  4LTZ A;  3Q2Z A;  5DHK A;  5DW7 A;  2E92 A;  5DIQ F;  3ZMB A;  4RYP A;  3RMG A;  4DWG A;  3ADZ A;  1WL0 A;  4GP2 A;  1V4E A;  3PYA A;  4F62 A;  3WCL A;  2ONG A;  1UBW A;  4OMG A;  2FOR A;  5DJP F;  2ZCS A;  4LPH F;  2E8U A;  4KQU A;  5EAS A;  3N1V F;  3V1V A;  3EGT A;  3KB9 A;  3G4F A;  5DGS F;  2ZCQ A;  2ZY1 A;  4EA2 A;  1YYT A;  4KK2 A;  2ZEU A;  2RAH A;  4RXD A;  4DHD A;  3SDQ A;  3DYH A;  4LZ3 A;  3P5R A;  3S4J A;  5B02 A;  4FP4 A;  4JXY A;  1YYU A;  3N3L F;  4NG6 A;  3LDW A;  3NPR A;  4LXW A;  5ILD A;  5B0L A;  1VG3 A;  3KRF A;  3WCF A;  2EWG A;  3VJ8 A;  3LGZ B;  4E1E A;  4DXJ A;  3VJE A;  4OGU A;  1ZW5 A;  3VJD A;  2E93 A;  4E9Z A;  4JVJ F;  2ZEV A;  3Q2Q A;  1UBX A;  5KSX F;  5DGM F;  5B0M A;  3PKO A;  4XQR F;  1DGP A;  1YJ4 A;  4LOB A;  3LMD A;  4LFG A;  5A0K A;  2OPN A;  4NFJ F;  5B01 A;  4LPG F;  5E8K A;  3WCM A;  1HXC A;  2E4O A;  5IL3 A;  4P0W A;  4FJQ A;  4MC3 A;  3UCA A;  3BNY A;  1HXG A;  3KRF B;  1N23 A;  3M9U A;  3ACW A;  1YQ7 A;  1YHM A;  2O1O A;  3NF2 A;  2F94 F;  5HNA A;  4K10 A;  3CC9 A;  4LZ0 A;  3VJC A;  3IPI A;  1RQI A;  4GP1 A;  3WEJ A;  3W7F A;  3ZL6 A;  4KQS A;  1N21 A;  3LZ9 A;  3Q1O A;  4DEM F;  3OAC A;  1HM7 A;  2FTZ A;  1N1B A;  5HN7 A;  5A0J A;  1YHL A;  2E8W A;  2Z7H A;  4RXA A;  3N0F A;  5DGN F;  1KIZ A;  4GA3 A;  4RXC A;  1WMW A;  4PVY F;  5DHI A;  3CP6 A;  4LA5 A;  3Q30 A;  4H5C F;  4KQ5 A;  4KUX A;  3WCB A;  3N5J F;  5JV2 F;  1VG4 A;  2Q9Y A;  3P41 A;  4KVI A;  3APZ A;  4KWD A;  3MAV A;  2Z52 A;  5E8L A;  5EAU A;  3N1W F;  5B0I A;  4H5E F;  2E90 A;  1KIY A;  2Q9Z A;  3OAC B;  3IBA A;  4KKM A;  3WJK A;  5ILZ A;  3LVS A;  3WEG A;  5JV1 F;  5IMN A;  3NPK A;  3WC9 A;  4LUU A;  2AZL A;  3OAB A;  5EAT A;  3RBM A;  3SDR A;  2F8Z F;  3WE9 A;  2DH4 A;  4N1Z F;  3EZ3 A;  5E8H A;  1N22 A;  3S9V A;  1UBY A;  1JFG A;  3WCE A;  2H8O A;  4KFA A;  5ERN A;  4F6V A;  5DJV F;  2AEK A;  3VJB A;  1V4J A;  3WEK A;  5ERM A;  1RTR A;  3N5H F;  4RNQ A;  5IMP A;  5IK0 A;  4KVD A;  4WK5 A;  2AZJ A;  2Q58 A;  3WSB A;  1EZF A;  3SDT A;  3AQ0 A;  3CKE A;  3LGK A;  1V4I A;  3AQB B;  4F6X A;  2Z4X A;  5B0K A;  5ILY A;  4MC0 A;  4KVW A;  2AET A;  1VG6 A;  3VJ9 A;  4N9U A;  5IKA A;  5JV0 F;  3WCJ A;  3QKC A;  4P0X A;  3OAB B;  5CG5 A;  5AEL A;  5B00 A;  2Z50 A;  3SDV A;  4L2X F;  2F8C F;  1JFA A;  4NKE A;  2VF6 A;  4JZB A;  5ILK A;  4XQT F;  5C05 A;  5IK9 A;  4NFI F;  5B0J A;  4DWB A;  3VJA A;  3WEF A;  3KRC A;  5DJR F;  2F7M F;  3N3D A;  2AZK A;  3KRA A;  1N20 A;  1WY0 A;  4QPF A;  1N1Z A;  4ZQ8 A;  4EA1 A;  5JUZ F;  5IM1 A;  3WCD A;  1YV5 A;  3ZOU A;  2F89 F;  5ILJ A;  1YYQ A;  3OYR A;  4HD1 A;  4OMH A;  1RQJ A;  3KRP A;  1WL1 A;  2J1P A;  4DZW A;  4MC8 A;  2F92 F;  5AYP A;  4XQS F;  3N46 F;  5IVG A;  1YYS A;  1N24 A;  1DI1 A;  2E95 A;  3ID0 A;  2E91 A;  2J5C A;  3V1X A;  4LLS A;  4E9U A;  2J1O A;  3LK5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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