3V66A

Human squalene synthase in complex with 2-(1-{2-[(4r,6s)-8-chloro-6-(2,3-dimethoxyphenyl)-4h,6h-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]acetyl}-4-piperidinyl)acetic acid
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
335
structure length
335
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Squalene synthase
publication title Discovery of novel tricyclic compounds as squalene synthase inhibitors
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase/transferase inhibitor
total genus 142
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3v66A00
2H8OA 3WEKA 4F6XA 3G4FA 1YYQA 3UCAA 3KROB 3N1WF 1RTRA 3P8RA 5B03A 5H9DA 3QQVA 3SDVA 4KQ5A 1WL1A 3WJKA 1EZFA 2ZY1A 5B0MA 3KBKA 1DI1A 4E9ZA 1YHMA 3M00A 5ILYA 1FPSA 2AZJA 3NRIA 3PH7A 5B0KA 3LJIA 1UBXA 5HN8A 5ERNA 3AQCB 2Z4VA 3ZMCA 2E8VA 2I19A 4KVYA 1V4HA 4LZ3A 2ZCRA 3NF2A 1YHKA 3N3DA 3WSAA 5ILKA 5IK6A 1DGPA 4H5CF 3CC9A 1WKZA 4XQSF 5EASA 3ZOUA 3RBMA 2Q9ZA 3MAVA 3TFNA 1WL3A 3P5RA 5E8HA 3TFPA 2Q58A 3LVSA 1KIYA 2F9KF 3BNXA 4PVYF 3OACB 3WEJA 2AETA 3KROA 3ICMA 3LDWA 5HN7A 1VG2A 4RXCA 4ZQ8A 3KRPB 5DIQF 3SDRA 3P5PA 3WEFA 3WCLA 2E94A 3TFVA 4EA0A 3WCFA 3WCMA 3LEEA 5C05A 4JXNA 2Q9YA 3MZVA 3N1VF 2EWGA 1N1BA 2Z7HA 3TC1A 2AZLA 4RXDA 1JFAA 3KRFB 1YQ7A 1N22A 3VJDA 4H5DF 1RQIA 4RNQA 1V4KA 4KVWA 5ILZA 4LPHF 5IKAA 5IL8A 5IK0A 3SDQA 2E95A 3PDEA 4LZ0A 1N20A 4JXYA 2ONGA 3WEGA 2RAHA 1N23A 3N5HF 3ZL6A 4KKMA 1YYTA 4KFAA 4OKZA 3OACA 2AZKA 4QPFA 3LSNA 5DHIA 5B00A 3N6KF 1V4EA 3V1XA 3TS7A 3NPKA 3KRPA 2Z4XA 2DH4A 4P0XA 4GP1A 4F6VA 4HD1A 1N24A 3Q1OA 4EA1A 3AQ0A 5IK9A 5B01A 3LOMA 3CKEA 1HX9A 3WCBA 4NG6A 3KB9A 2AEKA 3KRFA 5DJPF 3ICZA 3SAEA 4P0WA 4N9UA 4LTVA 1VG7A 1N21A 3CP6A 1HM7A 3ICKA 2J1OA 1RQJA 4K10A 1VG3A 3P8LA 4PVXF 3WCJA 1ZW5A 3VJAA 2E90A 2F8ZF 5HNAA 4DWBA 4KK2A 4Q23A 5ILJA 5ILHA 5HN9A 4NFIF 1JFGA 4GP2A 5IN8A 1UBWA 3VJCA 3WCAA 5B02A 4LLSA 3LMDA 2E8TA 4MC8A 3ID0A 2PS8A 4NFJF 5DJVF 5JA0F 3WCHA 4LFGA 5B0LA 1WY0A 3QKCA 3OABB 2F92F 4FJQA 4LZCA 4XQRF 2PS4A 4LFVF 4WK5A 3PKOA 4JZBA 5EROA 1PS1A 2E91A 1VG6A 5KSXF 4DXJA 2E8WA 4LUUA 4RYPA 2FTZA 3EGTA 3RYWA 4FP4A 5CG6A 3WC9A 3ACWA 4UMJA 2ZCQA 4DWGA 3Q2ZA 3RMGA 3VJ8A 4OMHA 5DZ2A 5JV0F 5ER8A 4P0VA 2E93A 3WJOA 4LFEA 3WCDA 5E8KA 3ZMBA 3N49F 3WCGA 3RYEA 2ONHA 3WCEA 4DZWA 4XQTF 3WEIA 3G4DA 3OABA 4JZXA 2QISA 5JUZF 5CG5A 3LG5A 4RXEA 5AYPA 2ZEVA 3IBAA 5IKHA 3SDUA 4LOBA 3M01A 2P1CA 3N3LF 3M0GA 4LTZA 2ZEUA 3V66A 5A0JA 2ZCSA 2OPMA 5IMNA 3WEHA 4H5EF 2Z4YA 3BNYA 1YJ4A 1WMWA 5IMIA 3M9UA 3PYBA 4KVIA 3VJEA 4KVDA 4OGUA 2VF6A 2PS6A 4LXWA 1HXCA 4KPDA 5DHKA 5E8LA 2J1PA 4OMGA 5ERMA 3LGKA 3EFQA 2F7MF 3N0FA 2Z4WA 1N1ZA 3ACXA 4E1EA 5DGNF 3KRAB 5EAUA 5IVGA 3LZ9A 3B7LA 2J5CA 2F8CF 3M02A 5IMPA 1YYUA 3AQBB 2E8UA 4F62A 5B0JA 3DYGA 1YV5A 3ZCDA 1YYSA 4DEMF 5A0IA 1HXAA 2Q80A 4RXAA 1UBVA 3Q2QA 4EA2A 2OA6A 3APZA 5DGSF 2O1OA 1VG4A 3LGZB 2E8XA 1WL0A 4DI5A 5DJRF 3WCIA 4KPJA 4N1ZF 2PS7A 4LPGF 2PS5A 5AELA 4KQSA 3ACYA 4MC3A 2Z4ZA 4JVJF 5A0KA 3AE0A 5DGMF 2OPNA 3LLWA 2ZCOA 3Q30A 5JV2F 1YHLA 3KRCB 3WCCA 2Z50A 4GAXA 2F89F 3IPIA 3KRAA 3NPRA 4E9UA 4KUXA 4KWDA 5JV1F 2E92A 3WSBA 3W7FA 3DYHA 5AHUB 3OYRA 5AFXA 3ASXA 4JYXA 4NUAA 3S9VA 5DW7A 5B0IA 4GA3A 2FORA 3PYAA 5EATA 1YYRA 3EZ3A 3S4JA 3P41A 2Z52A 5IL3A 4OKMA 2AELA 3N0GA 4NKFA 1HXGA 3WJNA 1V4IA 1WL2A 5ILDA 3SDTA 3VJ9A 1HM4A 3N45F 2Z78A 1V4JA 2E4OA 5ILIA 3ADZA 3ICNA 3DYFA 1KIZA 4LLTA 4QXSF 4KQUA 4LA5A 3V1VA 3WE9A 4LA6A 4NKEA 4MC0A 5IM1A 4NFKF 4L2XF 5I1UA 3N5JF 3VJBA 4DHDA 2OGDA 2F94F 4LIXA 3KRCA 3N46F 2Z7IA 3LK5A 1UBYA
chains in the Genus database with same CATH superfamily
2H8OA 3WEKA 4F6XA 3G4FA 1YYQA 3UCAA 3KROB 3N1WF 1RTRA 3P8RA 5B03A 5H9DA 3QQVA 3SDVA 4KQ5A 1WL1A 3WJKA 1EZFA 2ZY1A 5B0MA 3KBKA 1DI1A 4E9ZA 1YHMA 3M00A 5ILYA 1FPSA 2AZJA 3NRIA 3PH7A 5B0KA 3LJIA 1UBXA 5HN8A 5ERNA 3AQCB 2Z4VA 3ZMCA 2E8VA 2I19A 4KVYA 1V4HA 4LZ3A 2ZCRA 3NF2A 1YHKA 3N3DA 3WSAA 5ILKA 5IK6A 1DGPA 4H5CF 3CC9A 1WKZA 4XQSF 5EASA 3ZOUA 3RBMA 2Q9ZA 3MAVA 3TFNA 1WL3A 3P5RA 5E8HA 3TFPA 2Q58A 3LVSA 1KIYA 2F9KF 3BNXA 4PVYF 3OACB 3WEJA 2AETA 3KROA 3ICMA 3LDWA 5HN7A 1VG2A 4RXCA 4ZQ8A 3KRPB 5DIQF 3SDRA 3P5PA 3WEFA 3WCLA 2E94A 3TFVA 4EA0A 3WCFA 3WCMA 3LEEA 5C05A 4JXNA 2Q9YA 3MZVA 3N1VF 2EWGA 1N1BA 2Z7HA 3TC1A 2AZLA 4RXDA 1JFAA 3KRFB 1YQ7A 1N22A 3VJDA 4H5DF 1RQIA 4RNQA 1V4KA 4KVWA 5ILZA 4LPHF 5IKAA 5IL8A 5IK0A 3SDQA 2E95A 3PDEA 4LZ0A 1N20A 4JXYA 2ONGA 3WEGA 2RAHA 1N23A 3N5HF 3ZL6A 4KKMA 1YYTA 4KFAA 4OKZA 3OACA 2AZKA 4QPFA 3LSNA 5DHIA 5B00A 3N6KF 1V4EA 3V1XA 3TS7A 3NPKA 3KRPA 2Z4XA 2DH4A 4P0XA 4GP1A 4F6VA 4HD1A 1N24A 3Q1OA 4EA1A 3AQ0A 5IK9A 5B01A 3LOMA 3CKEA 1HX9A 3WCBA 4NG6A 3KB9A 2AEKA 3KRFA 5DJPF 3ICZA 3SAEA 4P0WA 4N9UA 4LTVA 1VG7A 1N21A 3CP6A 1HM7A 3ICKA 2J1OA 1RQJA 4K10A 1VG3A 3P8LA 4PVXF 3WCJA 1ZW5A 3VJAA 2E90A 2F8ZF 5HNAA 4DWBA 4KK2A 4Q23A 5ILJA 5ILHA 5HN9A 4NFIF 1JFGA 4GP2A 5IN8A 1UBWA 3VJCA 3WCAA 5B02A 4LLSA 3LMDA 2E8TA 4MC8A 3ID0A 2PS8A 4NFJF 5DJVF 5JA0F 3WCHA 4LFGA 5B0LA 1WY0A 3QKCA 3OABB 2F92F 4FJQA 4LZCA 4XQRF 2PS4A 4LFVF 4WK5A 3PKOA 4JZBA 5EROA 1PS1A 2E91A 1VG6A 5KSXF 4DXJA 2E8WA 4LUUA 4RYPA 2FTZA 3EGTA 3RYWA 4FP4A 5CG6A 3WC9A 3ACWA 4UMJA 2ZCQA 4DWGA 3Q2ZA 3RMGA 3VJ8A 4OMHA 5DZ2A 5JV0F 5ER8A 4P0VA 2E93A 3WJOA 4LFEA 3WCDA 5E8KA 3ZMBA 3N49F 3WCGA 3RYEA 2ONHA 3WCEA 4DZWA 4XQTF 3WEIA 3G4DA 3OABA 4JZXA 2QISA 5JUZF 5CG5A 3LG5A 4RXEA 5AYPA 2ZEVA 3IBAA 5IKHA 3SDUA 4LOBA 3M01A 2P1CA 3N3LF 3M0GA 4LTZA 2ZEUA 3V66A 5A0JA 2ZCSA 2OPMA 5IMNA 3WEHA 4H5EF 2Z4YA 3BNYA 1YJ4A 1WMWA 5IMIA 3M9UA 3PYBA 4KVIA 3VJEA 4KVDA 4OGUA 2VF6A 2PS6A 4LXWA 1HXCA 4KPDA 5DHKA 5E8LA 2J1PA 4OMGA 5ERMA 3LGKA 3EFQA 2F7MF 3N0FA 2Z4WA 1N1ZA 3ACXA 4E1EA 5DGNF 3KRAB 5EAUA 5IVGA 3LZ9A 3B7LA 2J5CA 2F8CF 3M02A 5IMPA 1YYUA 3AQBB 2E8UA 4F62A 5B0JA 3DYGA 1YV5A 3ZCDA 1YYSA 4DEMF 5A0IA 1HXAA 2Q80A 4RXAA 1UBVA 3Q2QA 4EA2A 2OA6A 3APZA 5DGSF 2O1OA 1VG4A 3LGZB 2E8XA 1WL0A 4DI5A 5DJRF 3WCIA 4KPJA 4N1ZF 2PS7A 4LPGF 2PS5A 5AELA 4KQSA 3ACYA 4MC3A 2Z4ZA 4JVJF 5A0KA 3AE0A 5DGMF 2OPNA 3LLWA 2ZCOA 3Q30A 5JV2F 1YHLA 3KRCB 3WCCA 2Z50A 4GAXA 2F89F 3IPIA 3KRAA 3NPRA 4E9UA 4KUXA 4KWDA 5JV1F 2E92A 3WSBA 3W7FA 3DYHA 5AHUB 3OYRA 5AFXA 3ASXA 4JYXA 4NUAA 3S9VA 5DW7A 5B0IA 4GA3A 2FORA 3PYAA 5EATA 1YYRA 3EZ3A 3S4JA 3P41A 2Z52A 5IL3A 4OKMA 2AELA 3N0GA 4NKFA 1HXGA 3WJNA 1V4IA 1WL2A 5ILDA 3SDTA 3VJ9A 1HM4A 3N45F 2Z78A 1V4JA 2E4OA 5ILIA 3ADZA 3ICNA 3DYFA 1KIZA 4LLTA 4QXSF 4KQUA 4LA5A 3V1VA 3WE9A 4LA6A 4NKEA 4MC0A 5IM1A 4NFKF 4L2XF 5I1UA 3N5JF 3VJBA 4DHDA 2OGDA 2F94F 4LIXA 3KRCA 3N46F 2Z7IA 3LK5A 1UBYA
chains in the Genus database with same CATH topology
2H8OA 3WEKA 4F6XA 3G4FA 1YYQA 3UCAA 3KROB 3N1WF 1RTRA 3P8RA 5B03A 5H9DA 3QQVA 3SDVA 4KQ5A 1WL1A 3WJKA 1EZFA 2ZY1A 5B0MA 3KBKA 1DI1A 4E9ZA 1YHMA 3M00A 5ILYA 1FPSA 2AZJA 3NRIA 3PH7A 5B0KA 3LJIA 1UBXA 5HN8A 5ERNA 3AQCB 2Z4VA 3ZMCA 2E8VA 2I19A 4KVYA 1V4HA 4LZ3A 2ZCRA 3NF2A 1YHKA 3N3DA 3WSAA 5ILKA 5IK6A 1DGPA 4H5CF 3CC9A 1WKZA 4XQSF 5EASA 3ZOUA 3RBMA 2Q9ZA 3MAVA 3TFNA 1WL3A 3P5RA 5E8HA 3TFPA 2Q58A 3LVSA 1KIYA 2F9KF 3BNXA 4PVYF 3OACB 3WEJA 2AETA 3KROA 3ICMA 3LDWA 5HN7A 1VG2A 4RXCA 4ZQ8A 3KRPB 5DIQF 3SDRA 3P5PA 3WEFA 3WCLA 2E94A 3TFVA 4EA0A 3WCFA 3WCMA 3LEEA 5C05A 4JXNA 2Q9YA 3MZVA 3N1VF 2EWGA 1N1BA 2Z7HA 3TC1A 2AZLA 4RXDA 1JFAA 3KRFB 1YQ7A 1N22A 3VJDA 4H5DF 1RQIA 4RNQA 1V4KA 4KVWA 5ILZA 4LPHF 5IKAA 5IL8A 5IK0A 3SDQA 2E95A 3PDEA 4LZ0A 1N20A 4JXYA 2ONGA 3WEGA 2RAHA 1N23A 3N5HF 3ZL6A 4KKMA 1YYTA 4KFAA 4OKZA 3OACA 2AZKA 4QPFA 3LSNA 5DHIA 5B00A 3N6KF 1V4EA 3V1XA 3TS7A 3NPKA 3KRPA 2Z4XA 2DH4A 4P0XA 4GP1A 4F6VA 4HD1A 1N24A 3Q1OA 4EA1A 3AQ0A 5IK9A 5B01A 3LOMA 3CKEA 1HX9A 3WCBA 4NG6A 3KB9A 2AEKA 3KRFA 5DJPF 3ICZA 3SAEA 4P0WA 4N9UA 4LTVA 1VG7A 1N21A 3CP6A 1HM7A 3ICKA 2J1OA 1RQJA 4K10A 1VG3A 3P8LA 4PVXF 3WCJA 1ZW5A 3VJAA 2E90A 2F8ZF 5HNAA 4DWBA 4KK2A 4Q23A 5ILJA 5ILHA 5HN9A 4NFIF 1JFGA 4GP2A 5IN8A 1UBWA 3VJCA 3WCAA 5B02A 4LLSA 3LMDA 2E8TA 4MC8A 3ID0A 2PS8A 4NFJF 5DJVF 5JA0F 3WCHA 4LFGA 5B0LA 1WY0A 3QKCA 3OABB 2F92F 4FJQA 4LZCA 4XQRF 2PS4A 4LFVF 4WK5A 3PKOA 4JZBA 5EROA 1PS1A 2E91A 1VG6A 5KSXF 4DXJA 2E8WA 4LUUA 4RYPA 2FTZA 3EGTA 3RYWA 4FP4A 5CG6A 3WC9A 3ACWA 4UMJA 2ZCQA 4DWGA 3Q2ZA 3RMGA 3VJ8A 4OMHA 5DZ2A 5JV0F 5ER8A 4P0VA 2E93A 3WJOA 4LFEA 3WCDA 5E8KA 3ZMBA 3N49F 3WCGA 3RYEA 2ONHA 3WCEA 4DZWA 4XQTF 3WEIA 3G4DA 3OABA 4JZXA 2QISA 5JUZF 5CG5A 3LG5A 4RXEA 5AYPA 2ZEVA 3IBAA 5IKHA 3SDUA 4LOBA 3M01A 2P1CA 3N3LF 3M0GA 4LTZA 2ZEUA 3V66A 5A0JA 2ZCSA 2OPMA 5IMNA 3WEHA 4H5EF 2Z4YA 3BNYA 1YJ4A 1WMWA 5IMIA 3M9UA 3PYBA 4KVIA 3VJEA 4KVDA 4OGUA 2VF6A 2PS6A 4LXWA 1HXCA 4KPDA 5DHKA 5E8LA 2J1PA 4OMGA 5ERMA 3LGKA 3EFQA 2F7MF 3N0FA 2Z4WA 1N1ZA 3ACXA 4E1EA 5DGNF 3KRAB 5EAUA 5IVGA 3LZ9A 3B7LA 2J5CA 2F8CF 3M02A 5IMPA 1YYUA 3AQBB 2E8UA 4F62A 5B0JA 3DYGA 1YV5A 3ZCDA 1YYSA 4DEMF 5A0IA 1HXAA 2Q80A 4RXAA 1UBVA 3Q2QA 4EA2A 2OA6A 3APZA 5DGSF 2O1OA 1VG4A 3LGZB 2E8XA 1WL0A 4DI5A 5DJRF 3WCIA 4KPJA 4N1ZF 2PS7A 4LPGF 2PS5A 5AELA 4KQSA 3ACYA 4MC3A 2Z4ZA 4JVJF 5A0KA 3AE0A 5DGMF 2OPNA 3LLWA 2ZCOA 3Q30A 5JV2F 1YHLA 3KRCB 3WCCA 2Z50A 4GAXA 2F89F 3IPIA 3KRAA 3NPRA 4E9UA 4KUXA 4KWDA 5JV1F 2E92A 3WSBA 3W7FA 3DYHA 5AHUB 3OYRA 5AFXA 3ASXA 4JYXA 4NUAA 3S9VA 5DW7A 5B0IA 4GA3A 2FORA 3PYAA 5EATA 1YYRA 3EZ3A 3S4JA 3P41A 2Z52A 5IL3A 4OKMA 2AELA 3N0GA 4NKFA 1HXGA 3WJNA 1V4IA 1WL2A 5ILDA 3SDTA 3VJ9A 1HM4A 3N45F 2Z78A 1V4JA 2E4OA 5ILIA 3ADZA 3ICNA 3DYFA 1KIZA 4LLTA 4QXSF 4KQUA 4LA5A 3V1VA 3WE9A 4LA6A 4NKEA 4MC0A 5IM1A 4NFKF 4L2XF 5I1UA 3N5JF 3VJBA 4DHDA 2OGDA 2F94F 4LIXA 3KRCA 3N46F 2Z7IA 3LK5A 1UBYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2H8O A;  3WEK A;  4F6X A;  3G4F A;  1YYQ A;  3UCA A;  3KRO B;  3N1W F;  1RTR A;  3P8R A;  5B03 A;  5H9D A;  3QQV A;  3SDV A;  4KQ5 A;  1WL1 A;  3WJK A;  1EZF A;  2ZY1 A;  5B0M A;  3KBK A;  1DI1 A;  4E9Z A;  1YHM A;  3M00 A;  5ILY A;  1FPS A;  2AZJ A;  3NRI A;  3PH7 A;  5B0K A;  3LJI A;  1UBX A;  5HN8 A;  5ERN A;  3AQC B;  2Z4V A;  3ZMC A;  2E8V A;  2I19 A;  4KVY A;  1V4H A;  4LZ3 A;  2ZCR A;  3NF2 A;  1YHK A;  3N3D A;  3WSA A;  5ILK A;  5IK6 A;  1DGP A;  4H5C F;  3CC9 A;  1WKZ A;  4XQS F;  5EAS A;  3ZOU A;  3RBM A;  2Q9Z A;  3MAV A;  3TFN A;  1WL3 A;  3P5R A;  5E8H A;  3TFP A;  2Q58 A;  3LVS A;  1KIY A;  2F9K F;  3BNX A;  4PVY F;  3OAC B;  3WEJ A;  2AET A;  3KRO A;  3ICM A;  3LDW A;  5HN7 A;  1VG2 A;  4RXC A;  4ZQ8 A;  3KRP B;  5DIQ F;  3SDR A;  3P5P A;  3WEF A;  3WCL A;  2E94 A;  3TFV A;  4EA0 A;  3WCF A;  3WCM A;  3LEE A;  5C05 A;  4JXN A;  2Q9Y A;  3MZV A;  3N1V F;  2EWG A;  1N1B A;  2Z7H A;  3TC1 A;  2AZL A;  4RXD A;  1JFA A;  3KRF B;  1YQ7 A;  1N22 A;  3VJD A;  4H5D F;  1RQI A;  4RNQ A;  1V4K A;  4KVW A;  5ILZ A;  4LPH F;  5IKA A;  5IL8 A;  5IK0 A;  3SDQ A;  2E95 A;  3PDE A;  4LZ0 A;  1N20 A;  4JXY A;  2ONG A;  3WEG A;  2RAH A;  1N23 A;  3N5H F;  3ZL6 A;  4KKM A;  1YYT A;  4KFA A;  4OKZ A;  3OAC A;  2AZK A;  4QPF A;  3LSN A;  5DHI A;  5B00 A;  3N6K F;  1V4E A;  3V1X A;  3TS7 A;  3NPK A;  3KRP A;  2Z4X A;  2DH4 A;  4P0X A;  4GP1 A;  4F6V A;  4HD1 A;  1N24 A;  3Q1O A;  4EA1 A;  3AQ0 A;  5IK9 A;  5B01 A;  3LOM A;  3CKE A;  1HX9 A;  3WCB A;  4NG6 A;  3KB9 A;  2AEK A;  3KRF A;  5DJP F;  3ICZ A;  3SAE A;  4P0W A;  4N9U A;  4LTV A;  1VG7 A;  1N21 A;  3CP6 A;  1HM7 A;  3ICK A;  2J1O A;  1RQJ A;  4K10 A;  1VG3 A;  3P8L A;  4PVX F;  3WCJ A;  1ZW5 A;  3VJA A;  2E90 A;  2F8Z F;  5HNA A;  4DWB A;  4KK2 A;  4Q23 A;  5ILJ A;  5ILH A;  5HN9 A;  4NFI F;  1JFG A;  4GP2 A;  5IN8 A;  1UBW A;  3VJC A;  3WCA A;  5B02 A;  4LLS A;  3LMD A;  2E8T A;  4MC8 A;  3ID0 A;  2PS8 A;  4NFJ F;  5DJV F;  5JA0 F;  3WCH A;  4LFG A;  5B0L A;  1WY0 A;  3QKC A;  3OAB B;  2F92 F;  4FJQ A;  4LZC A;  4XQR F;  2PS4 A;  4LFV F;  4WK5 A;  3PKO A;  4JZB A;  5ERO A;  1PS1 A;  2E91 A;  1VG6 A;  5KSX F;  4DXJ A;  2E8W A;  4LUU A;  4RYP A;  2FTZ A;  3EGT A;  3RYW A;  4FP4 A;  5CG6 A;  3WC9 A;  3ACW A;  4UMJ A;  2ZCQ A;  4DWG A;  3Q2Z A;  3RMG A;  3VJ8 A;  4OMH A;  5DZ2 A;  5JV0 F;  5ER8 A;  4P0V A;  2E93 A;  3WJO A;  4LFE A;  3WCD A;  5E8K A;  3ZMB A;  3N49 F;  3WCG A;  3RYE A;  2ONH A;  3WCE A;  4DZW A;  4XQT F;  3WEI A;  3G4D A;  3OAB A;  4JZX A;  2QIS A;  5JUZ F;  5CG5 A;  3LG5 A;  4RXE A;  5AYP A;  2ZEV A;  3IBA A;  5IKH A;  3SDU A;  4LOB A;  3M01 A;  2P1C A;  3N3L F;  3M0G A;  4LTZ A;  2ZEU A;  3V66 A;  5A0J A;  2ZCS A;  2OPM A;  5IMN A;  3WEH A;  4H5E F;  2Z4Y A;  3BNY A;  1YJ4 A;  1WMW A;  5IMI A;  3M9U A;  3PYB A;  4KVI A;  3VJE A;  4KVD A;  4OGU A;  2VF6 A;  2PS6 A;  4LXW A;  1HXC A;  4KPD A;  5DHK A;  5E8L A;  2J1P A;  4OMG A;  5ERM A;  3LGK A;  3EFQ A;  2F7M F;  3N0F A;  2Z4W A;  1N1Z A;  3ACX A;  4E1E A;  5DGN F;  3KRA B;  5EAU A;  5IVG A;  3LZ9 A;  3B7L A;  2J5C A;  2F8C F;  3M02 A;  5IMP A;  1YYU A;  3AQB B;  2E8U A;  4F62 A;  5B0J A;  3DYG A;  1YV5 A;  3ZCD A;  1YYS A;  4DEM F;  5A0I A;  1HXA A;  2Q80 A;  4RXA A;  1UBV A;  3Q2Q A;  4EA2 A;  2OA6 A;  3APZ A;  5DGS F;  2O1O A;  1VG4 A;  3LGZ B;  2E8X A;  1WL0 A;  4DI5 A;  5DJR F;  3WCI A;  4KPJ A;  4N1Z F;  2PS7 A;  4LPG F;  2PS5 A;  5AEL A;  4KQS A;  3ACY A;  4MC3 A;  2Z4Z A;  4JVJ F;  5A0K A;  3AE0 A;  5DGM F;  2OPN A;  3LLW A;  2ZCO A;  3Q30 A;  5JV2 F;  1YHL A;  3KRC B;  3WCC A;  2Z50 A;  4GAX A;  2F89 F;  3IPI A;  3KRA A;  3NPR A;  4E9U A;  4KUX A;  4KWD A;  5JV1 F;  2E92 A;  3WSB A;  3W7F A;  3DYH A;  5AHU B;  3OYR A;  5AFX A;  3ASX A;  4JYX A;  4NUA A;  3S9V A;  5DW7 A;  5B0I A;  4GA3 A;  2FOR A;  3PYA A;  5EAT A;  1YYR A;  3EZ3 A;  3S4J A;  3P41 A;  2Z52 A;  5IL3 A;  4OKM A;  2AEL A;  3N0G A;  4NKF A;  1HXG A;  3WJN A;  1V4I A;  1WL2 A;  5ILD A;  3SDT A;  3VJ9 A;  1HM4 A;  3N45 F;  2Z78 A;  1V4J A;  2E4O A;  5ILI A;  3ADZ A;  3ICN A;  3DYF A;  1KIZ A;  4LLT A;  4QXS F;  4KQU A;  4LA5 A;  3V1V A;  3WE9 A;  4LA6 A;  4NKE A;  4MC0 A;  5IM1 A;  4NFK F;  4L2X F;  5I1U A;  3N5J F;  3VJB A;  4DHD A;  2OGD A;  2F94 F;  4LIX A;  3KRC A;  3N46 F;  2Z7I A;  3LK5 A;  1UBY A; 
#chains in the Genus database with same CATH topology
 2H8O A;  3WEK A;  4F6X A;  3G4F A;  1YYQ A;  3UCA A;  3KRO B;  3N1W F;  1RTR A;  3P8R A;  5B03 A;  5H9D A;  3QQV A;  3SDV A;  4KQ5 A;  1WL1 A;  3WJK A;  1EZF A;  2ZY1 A;  5B0M A;  3KBK A;  1DI1 A;  4E9Z A;  1YHM A;  3M00 A;  5ILY A;  1FPS A;  2AZJ A;  3NRI A;  3PH7 A;  5B0K A;  3LJI A;  1UBX A;  5HN8 A;  5ERN A;  3AQC B;  2Z4V A;  3ZMC A;  2E8V A;  2I19 A;  4KVY A;  1V4H A;  4LZ3 A;  2ZCR A;  3NF2 A;  1YHK A;  3N3D A;  3WSA A;  5ILK A;  5IK6 A;  1DGP A;  4H5C F;  3CC9 A;  1WKZ A;  4XQS F;  5EAS A;  3ZOU A;  3RBM A;  2Q9Z A;  3MAV A;  3TFN A;  1WL3 A;  3P5R A;  5E8H A;  3TFP A;  2Q58 A;  3LVS A;  1KIY A;  2F9K F;  3BNX A;  4PVY F;  3OAC B;  3WEJ A;  2AET A;  3KRO A;  3ICM A;  3LDW A;  5HN7 A;  1VG2 A;  4RXC A;  4ZQ8 A;  3KRP B;  5DIQ F;  3SDR A;  3P5P A;  3WEF A;  3WCL A;  2E94 A;  3TFV A;  4EA0 A;  3WCF A;  3WCM A;  3LEE A;  5C05 A;  4JXN A;  2Q9Y A;  3MZV A;  3N1V F;  2EWG A;  1N1B A;  2Z7H A;  3TC1 A;  2AZL A;  4RXD A;  1JFA A;  3KRF B;  1YQ7 A;  1N22 A;  3VJD A;  4H5D F;  1RQI A;  4RNQ A;  1V4K A;  4KVW A;  5ILZ A;  4LPH F;  5IKA A;  5IL8 A;  5IK0 A;  3SDQ A;  2E95 A;  3PDE A;  4LZ0 A;  1N20 A;  4JXY A;  2ONG A;  3WEG A;  2RAH A;  1N23 A;  3N5H F;  3ZL6 A;  4KKM A;  1YYT A;  4KFA A;  4OKZ A;  3OAC A;  2AZK A;  4QPF A;  3LSN A;  5DHI A;  5B00 A;  3N6K F;  1V4E A;  3V1X A;  3TS7 A;  3NPK A;  3KRP A;  2Z4X A;  2DH4 A;  4P0X A;  4GP1 A;  4F6V A;  4HD1 A;  1N24 A;  3Q1O A;  4EA1 A;  3AQ0 A;  5IK9 A;  5B01 A;  3LOM A;  3CKE A;  1HX9 A;  3WCB A;  4NG6 A;  3KB9 A;  2AEK A;  3KRF A;  5DJP F;  3ICZ A;  3SAE A;  4P0W A;  4N9U A;  4LTV A;  1VG7 A;  1N21 A;  3CP6 A;  1HM7 A;  3ICK A;  2J1O A;  1RQJ A;  4K10 A;  1VG3 A;  3P8L A;  4PVX F;  3WCJ A;  1ZW5 A;  3VJA A;  2E90 A;  2F8Z F;  5HNA A;  4DWB A;  4KK2 A;  4Q23 A;  5ILJ A;  5ILH A;  5HN9 A;  4NFI F;  1JFG A;  4GP2 A;  5IN8 A;  1UBW A;  3VJC A;  3WCA A;  5B02 A;  4LLS A;  3LMD A;  2E8T A;  4MC8 A;  3ID0 A;  2PS8 A;  4NFJ F;  5DJV F;  5JA0 F;  3WCH A;  4LFG A;  5B0L A;  1WY0 A;  3QKC A;  3OAB B;  2F92 F;  4FJQ A;  4LZC A;  4XQR F;  2PS4 A;  4LFV F;  4WK5 A;  3PKO A;  4JZB A;  5ERO A;  1PS1 A;  2E91 A;  1VG6 A;  5KSX F;  4DXJ A;  2E8W A;  4LUU A;  4RYP A;  2FTZ A;  3EGT A;  3RYW A;  4FP4 A;  5CG6 A;  3WC9 A;  3ACW A;  4UMJ A;  2ZCQ A;  4DWG A;  3Q2Z A;  3RMG A;  3VJ8 A;  4OMH A;  5DZ2 A;  5JV0 F;  5ER8 A;  4P0V A;  2E93 A;  3WJO A;  4LFE A;  3WCD A;  5E8K A;  3ZMB A;  3N49 F;  3WCG A;  3RYE A;  2ONH A;  3WCE A;  4DZW A;  4XQT F;  3WEI A;  3G4D A;  3OAB A;  4JZX A;  2QIS A;  5JUZ F;  5CG5 A;  3LG5 A;  4RXE A;  5AYP A;  2ZEV A;  3IBA A;  5IKH A;  3SDU A;  4LOB A;  3M01 A;  2P1C A;  3N3L F;  3M0G A;  4LTZ A;  2ZEU A;  3V66 A;  5A0J A;  2ZCS A;  2OPM A;  5IMN A;  3WEH A;  4H5E F;  2Z4Y A;  3BNY A;  1YJ4 A;  1WMW A;  5IMI A;  3M9U A;  3PYB A;  4KVI A;  3VJE A;  4KVD A;  4OGU A;  2VF6 A;  2PS6 A;  4LXW A;  1HXC A;  4KPD A;  5DHK A;  5E8L A;  2J1P A;  4OMG A;  5ERM A;  3LGK A;  3EFQ A;  2F7M F;  3N0F A;  2Z4W A;  1N1Z A;  3ACX A;  4E1E A;  5DGN F;  3KRA B;  5EAU A;  5IVG A;  3LZ9 A;  3B7L A;  2J5C A;  2F8C F;  3M02 A;  5IMP A;  1YYU A;  3AQB B;  2E8U A;  4F62 A;  5B0J A;  3DYG A;  1YV5 A;  3ZCD A;  1YYS A;  4DEM F;  5A0I A;  1HXA A;  2Q80 A;  4RXA A;  1UBV A;  3Q2Q A;  4EA2 A;  2OA6 A;  3APZ A;  5DGS F;  2O1O A;  1VG4 A;  3LGZ B;  2E8X A;  1WL0 A;  4DI5 A;  5DJR F;  3WCI A;  4KPJ A;  4N1Z F;  2PS7 A;  4LPG F;  2PS5 A;  5AEL A;  4KQS A;  3ACY A;  4MC3 A;  2Z4Z A;  4JVJ F;  5A0K A;  3AE0 A;  5DGM F;  2OPN A;  3LLW A;  2ZCO A;  3Q30 A;  5JV2 F;  1YHL A;  3KRC B;  3WCC A;  2Z50 A;  4GAX A;  2F89 F;  3IPI A;  3KRA A;  3NPR A;  4E9U A;  4KUX A;  4KWD A;  5JV1 F;  2E92 A;  3WSB A;  3W7F A;  3DYH A;  5AHU B;  3OYR A;  5AFX A;  3ASX A;  4JYX A;  4NUA A;  3S9V A;  5DW7 A;  5B0I A;  4GA3 A;  2FOR A;  3PYA A;  5EAT A;  1YYR A;  3EZ3 A;  3S4J A;  3P41 A;  2Z52 A;  5IL3 A;  4OKM A;  2AEL A;  3N0G A;  4NKF A;  1HXG A;  3WJN A;  1V4I A;  1WL2 A;  5ILD A;  3SDT A;  3VJ9 A;  1HM4 A;  3N45 F;  2Z78 A;  1V4J A;  2E4O A;  5ILI A;  3ADZ A;  3ICN A;  3DYF A;  1KIZ A;  4LLT A;  4QXS F;  4KQU A;  4LA5 A;  3V1V A;  3WE9 A;  4LA6 A;  4NKE A;  4MC0 A;  5IM1 A;  4NFK F;  4L2X F;  5I1U A;  3N5J F;  3VJB A;  4DHD A;  2OGD A;  2F94 F;  4LIX A;  3KRC A;  3N46 F;  2Z7I A;  3LK5 A;  1UBY A; 
#chains in the Genus database with same CATH homology
 2H8O A;  3WEK A;  4F6X A;  3G4F A;  1YYQ A;  3UCA A;  3KRO B;  3N1W F;  1RTR A;  3P8R A;  5B03 A;  5H9D A;  3QQV A;  3SDV A;  4KQ5 A;  1WL1 A;  3WJK A;  1EZF A;  2ZY1 A;  5B0M A;  3KBK A;  1DI1 A;  4E9Z A;  1YHM A;  3M00 A;  5ILY A;  1FPS A;  2AZJ A;  3NRI A;  3PH7 A;  5B0K A;  3LJI A;  1UBX A;  5HN8 A;  5ERN A;  3AQC B;  2Z4V A;  3ZMC A;  2E8V A;  2I19 A;  4KVY A;  1V4H A;  4LZ3 A;  2ZCR A;  3NF2 A;  1YHK A;  3N3D A;  3WSA A;  5ILK A;  5IK6 A;  1DGP A;  4H5C F;  3CC9 A;  1WKZ A;  4XQS F;  5EAS A;  3ZOU A;  3RBM A;  2Q9Z A;  3MAV A;  3TFN A;  1WL3 A;  3P5R A;  5E8H A;  3TFP A;  2Q58 A;  3LVS A;  1KIY A;  2F9K F;  3BNX A;  4PVY F;  3OAC B;  3WEJ A;  2AET A;  3KRO A;  3ICM A;  3LDW A;  5HN7 A;  1VG2 A;  4RXC A;  4ZQ8 A;  3KRP B;  5DIQ F;  3SDR A;  3P5P A;  3WEF A;  3WCL A;  2E94 A;  3TFV A;  4EA0 A;  3WCF A;  3WCM A;  3LEE A;  5C05 A;  4JXN A;  2Q9Y A;  3MZV A;  3N1V F;  2EWG A;  1N1B A;  2Z7H A;  3TC1 A;  2AZL A;  4RXD A;  1JFA A;  3KRF B;  1YQ7 A;  1N22 A;  3VJD A;  4H5D F;  1RQI A;  4RNQ A;  1V4K A;  4KVW A;  5ILZ A;  4LPH F;  5IKA A;  5IL8 A;  5IK0 A;  3SDQ A;  2E95 A;  3PDE A;  4LZ0 A;  1N20 A;  4JXY A;  2ONG A;  3WEG A;  2RAH A;  1N23 A;  3N5H F;  3ZL6 A;  4KKM A;  1YYT A;  4KFA A;  4OKZ A;  3OAC A;  2AZK A;  4QPF A;  3LSN A;  5DHI A;  5B00 A;  3N6K F;  1V4E A;  3V1X A;  3TS7 A;  3NPK A;  3KRP A;  2Z4X A;  2DH4 A;  4P0X A;  4GP1 A;  4F6V A;  4HD1 A;  1N24 A;  3Q1O A;  4EA1 A;  3AQ0 A;  5IK9 A;  5B01 A;  3LOM A;  3CKE A;  1HX9 A;  3WCB A;  4NG6 A;  3KB9 A;  2AEK A;  3KRF A;  5DJP F;  3ICZ A;  3SAE A;  4P0W A;  4N9U A;  4LTV A;  1VG7 A;  1N21 A;  3CP6 A;  1HM7 A;  3ICK A;  2J1O A;  1RQJ A;  4K10 A;  1VG3 A;  3P8L A;  4PVX F;  3WCJ A;  1ZW5 A;  3VJA A;  2E90 A;  2F8Z F;  5HNA A;  4DWB A;  4KK2 A;  4Q23 A;  5ILJ A;  5ILH A;  5HN9 A;  4NFI F;  1JFG A;  4GP2 A;  5IN8 A;  1UBW A;  3VJC A;  3WCA A;  5B02 A;  4LLS A;  3LMD A;  2E8T A;  4MC8 A;  3ID0 A;  2PS8 A;  4NFJ F;  5DJV F;  5JA0 F;  3WCH A;  4LFG A;  5B0L A;  1WY0 A;  3QKC A;  3OAB B;  2F92 F;  4FJQ A;  4LZC A;  4XQR F;  2PS4 A;  4LFV F;  4WK5 A;  3PKO A;  4JZB A;  5ERO A;  1PS1 A;  2E91 A;  1VG6 A;  5KSX F;  4DXJ A;  2E8W A;  4LUU A;  4RYP A;  2FTZ A;  3EGT A;  3RYW A;  4FP4 A;  5CG6 A;  3WC9 A;  3ACW A;  4UMJ A;  2ZCQ A;  4DWG A;  3Q2Z A;  3RMG A;  3VJ8 A;  4OMH A;  5DZ2 A;  5JV0 F;  5ER8 A;  4P0V A;  2E93 A;  3WJO A;  4LFE A;  3WCD A;  5E8K A;  3ZMB A;  3N49 F;  3WCG A;  3RYE A;  2ONH A;  3WCE A;  4DZW A;  4XQT F;  3WEI A;  3G4D A;  3OAB A;  4JZX A;  2QIS A;  5JUZ F;  5CG5 A;  3LG5 A;  4RXE A;  5AYP A;  2ZEV A;  3IBA A;  5IKH A;  3SDU A;  4LOB A;  3M01 A;  2P1C A;  3N3L F;  3M0G A;  4LTZ A;  2ZEU A;  3V66 A;  5A0J A;  2ZCS A;  2OPM A;  5IMN A;  3WEH A;  4H5E F;  2Z4Y A;  3BNY A;  1YJ4 A;  1WMW A;  5IMI A;  3M9U A;  3PYB A;  4KVI A;  3VJE A;  4KVD A;  4OGU A;  2VF6 A;  2PS6 A;  4LXW A;  1HXC A;  4KPD A;  5DHK A;  5E8L A;  2J1P A;  4OMG A;  5ERM A;  3LGK A;  3EFQ A;  2F7M F;  3N0F A;  2Z4W A;  1N1Z A;  3ACX A;  4E1E A;  5DGN F;  3KRA B;  5EAU A;  5IVG A;  3LZ9 A;  3B7L A;  2J5C A;  2F8C F;  3M02 A;  5IMP A;  1YYU A;  3AQB B;  2E8U A;  4F62 A;  5B0J A;  3DYG A;  1YV5 A;  3ZCD A;  1YYS A;  4DEM F;  5A0I A;  1HXA A;  2Q80 A;  4RXA A;  1UBV A;  3Q2Q A;  4EA2 A;  2OA6 A;  3APZ A;  5DGS F;  2O1O A;  1VG4 A;  3LGZ B;  2E8X A;  1WL0 A;  4DI5 A;  5DJR F;  3WCI A;  4KPJ A;  4N1Z F;  2PS7 A;  4LPG F;  2PS5 A;  5AEL A;  4KQS A;  3ACY A;  4MC3 A;  2Z4Z A;  4JVJ F;  5A0K A;  3AE0 A;  5DGM F;  2OPN A;  3LLW A;  2ZCO A;  3Q30 A;  5JV2 F;  1YHL A;  3KRC B;  3WCC A;  2Z50 A;  4GAX A;  2F89 F;  3IPI A;  3KRA A;  3NPR A;  4E9U A;  4KUX A;  4KWD A;  5JV1 F;  2E92 A;  3WSB A;  3W7F A;  3DYH A;  5AHU B;  3OYR A;  5AFX A;  3ASX A;  4JYX A;  4NUA A;  3S9V A;  5DW7 A;  5B0I A;  4GA3 A;  2FOR A;  3PYA A;  5EAT A;  1YYR A;  3EZ3 A;  3S4J A;  3P41 A;  2Z52 A;  5IL3 A;  4OKM A;  2AEL A;  3N0G A;  4NKF A;  1HXG A;  3WJN A;  1V4I A;  1WL2 A;  5ILD A;  3SDT A;  3VJ9 A;  1HM4 A;  3N45 F;  2Z78 A;  1V4J A;  2E4O A;  5ILI A;  3ADZ A;  3ICN A;  3DYF A;  1KIZ A;  4LLT A;  4QXS F;  4KQU A;  4LA5 A;  3V1V A;  3WE9 A;  4LA6 A;  4NKE A;  4MC0 A;  5IM1 A;  4NFK F;  4L2X F;  5I1U A;  3N5J F;  3VJB A;  4DHD A;  2OGD A;  2F94 F;  4LIX A;  3KRC A;  3N46 F;  2Z7I A;  3LK5 A;  1UBY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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