5DJPF

Crystal structure of human fpps in complex with biaryl compound 5
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title Discovery of Novel Allosteric Non-Bisphosphonate Inhibitors of Farnesyl Pyrophosphate Synthase by Integrated Lead Finding.
pubmed doi rcsb
source organism Homo sapiens
total genus 127
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2015-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 5djpF00
3WCGA 1UBWA 4H5CF 2AEKA 4NKFA 3VJDA 3Q2QA 5DJRF 3RYEA 4RYPA 4LXWA 3P5PA 4LZCA 3CC9A 3RYWA 4KWDA 2E8VA 3DYHA 2H8OA 3KRCA 3BNXA 4XQRF 5ILHA 1WL2A 2ONGA 3ICKA 2E8WA 3Q2ZA 4LTZA 4NFJF 2PS4A 2E91A 4KK2A 1V4IA 3MAVA 3VJBA 1HM7A 3M0GA 3KRPA 4KKMA 5HN7A 4LLTA 5H9DA 5EAUA 4JXNA 4WK5A 2ZCRA 5AYPA 4LZ0A 3P41A 3NPRA 4DI5A 3M01A 5HN8A 3DYGA 2Z4WA 2Z7IA 4LA5A 3IPIA 4RXAA 3IBAA 4OKZA 3M9UA 2AELA 2E95A 2EWGA 4RXCA 3WCCA 2PS5A 2VF6A 3AQBB 4DEMF 3KBKA 3W7FA 3WCDA 1WL0A 2OPMA 3ZL6A 1YQ7A 3SAEA 4N9UA 3N6KF 3TC1A 4LOBA 1YYSA 3LMDA 3PDEA 3LOMA 4LLSA 5B00A 2Q9YA 1HM4A 2OGDA 3PKOA 4RNQA 3S9VA 3CP6A 2Z4VA 2PS8A 2F89F 1WL1A 2E93A 3N5JF 3ICNA 4DWGA 4DXJA 1WMWA 2Z78A 4EA1A 2ZCSA 2Z50A 3ADZA 4HD1A 1UBVA 3WSBA 3Q1OA 2F94F 3SDQA 3WEGA 4JZXA 2AETA 1UBYA 2QISA 5B0KA 2Q58A 2E8UA 5DW7A 4MC3A 3OABA 5JUZF 1N1BA 4OKMA 3WSAA 5B0LA 1HXCA 5EATA 1YYTA 1VG3A 2PS7A 1YYRA 1ZW5A 3PYAA 5IN8A 5ERNA 5B02A 4KVDA 2AZLA 2Z4XA 5JV1F 1HXGA 3NPKA 4JVJF 5ER8A 3ACYA 2ZY1A 5A0JA 3KRAB 4NUAA 5DHIA 3VJEA 1YYQA 4XQTF 3TFVA 4JYXA 5B01A 3RBMA 3WJOA 3LDWA 4Q23A 4DHDA 3TFNA 3VJAA 5A0KA 3LVSA 4OMGA 5IM1A 4NFIF 3V1VA 3P8LA 3WEIA 3WE9A 3KRFB 5E8HA 3WEFA 3B7LA 5B03A 1N20A 3WCMA 1YJ4A 4KVYA 4EA2A 3ACWA 1KIZA 3ICZA 3WCHA 5IVGA 2AZJA 1WKZA 5C05A 1EZFA 3RMGA 2E8XA 3N49F 3KRAA 5A0IA 3LJIA 2ZEVA 3LZ9A 3WCFA 2ONHA 3LLWA 3N45F 1V4EA 3OYRA 4LA6A 4QXSF 3V1XA 4E1EA 5ILIA 4KUXA 1UBXA 2DH4A 4KVIA 3P5RA 4E9UA 3LK5A 4P0XA 2F9KF 3WEKA 2J1PA 5CG6A 3MZVA 1N22A 1VG7A 5AFXA 1JFGA 3S4JA 4LIXA 3DYFA 3NF2A 5DGSF 5B0MA 3EGTA 4K10A 2FTZA 4RXEA 4KPDA 4UMJA 4E9ZA 3ASXA 3OACB 3LSNA 5E8LA 4H5EF 3LEEA 3ID0A 4H5DF 1RTRA 4KVWA 4P0VA 4NKEA 2E4OA 2F8CF 5HNAA 2Z7HA 4LPGF 4LZ3A 5B0IA 5IL8A 1N23A 4F6VA 3LGZB 5EASA 1HX9A 1FPSA 1V4HA 3UCAA 1YYUA 5IMNA 3WCJA 4GP1A 1V4KA 3N5HF 5ILKA 3WCLA 2FORA 3LGKA 5DGNF 3N1WF 4DWBA 3SDTA 2OA6A 4EA0A 3EZ3A 4LFVF 3AE0A 3AQCB 2ZCQA 5EROA 2E92A 3BNYA 3WEHA 3WJKA 3OACA 2J5CA 1VG2A 2P1CA 3ACXA 5ILDA 3SDUA 4KQUA 5JA0F 1VG4A 3KRCB 2Q80A 3ICMA 5HN9A 1RQJA 4GAXA 2Z52A 5IL3A 1YHLA 1DGPA 4KFAA 5E8KA 3ZMBA 4GA3A 4F6XA 3N3LF 4LFEA 2PS6A 3G4DA 2Z4YA 1N1ZA 3G4FA 5KSXF 4MC8A 3TS7A 4NFKF 4P0WA 3QKCA 3LG5A 1DI1A 2AZKA 3ZOUA 4L2XF 4KPJA 5ILZA 3WJNA 1WL3A 5B0JA 3SDVA 3N46F 3M02A 2ZCOA 3CKEA 2I19A 2O1OA 4KQSA 1WY0A 2OPNA 2ZEUA 3Q30A 3N1VF 3KRFA 5DJPF 3EFQA 5DGMF 3PH7A 1RQIA 5JV0F 1V4JA 3VJCA 2E8TA 4OGUA 5IK9A 4F62A 3QQVA 5IKHA 1VG6A 2J1OA 4LFGA 4FP4A 3KB9A 2RAHA 3WCEA 5IK6A 4XQSF 3V66A 1YV5A 5IK0A 4OMHA 3VJ9A 4RXDA 4QPFA 5IMPA 3WEJA 5AHUB 4N1ZF 3OABB 5IMIA 3SDRA 4LPHF 5JV2F 5ILYA 1HXAA 3KROB 3AQ0A 1YHKA 3ZMCA 4GP2A 2Q9ZA 3WCIA 4KQ5A 2Z4ZA 2E90A 5AELA 5I1UA 5ERMA 5DJVF 3N0GA 1JFAA 3N0FA 4FJQA 4DZWA 3PYBA 4PVXF 5DIQF 5DZ2A 5DHKA 3M00A 1PS1A 1N21A 3WC9A 4ZQ8A 1N24A 3N3DA 5ILJA 3NRIA 4PVYF 4JZBA 3WCBA 4JXYA 2F8ZF 1KIYA 4LTVA 3TFPA 3APZA 3KROA 2F7MF 4NG6A 4MC0A 3ZCDA 5IKAA 3VJ8A 2F92F 5CG5A 3KRPB 1YHMA 2E94A 3P8RA 4LUUA 3WCAA
chains in the Genus database with same CATH superfamily
3WCGA 1UBWA 4H5CF 2AEKA 4NKFA 3VJDA 3Q2QA 5DJRF 3RYEA 4RYPA 4LXWA 3P5PA 4LZCA 3CC9A 3RYWA 4KWDA 2E8VA 3DYHA 2H8OA 3KRCA 3BNXA 4XQRF 5ILHA 1WL2A 2ONGA 3ICKA 2E8WA 3Q2ZA 4LTZA 4NFJF 2PS4A 2E91A 4KK2A 1V4IA 3MAVA 3VJBA 1HM7A 3M0GA 3KRPA 4KKMA 5HN7A 4LLTA 5H9DA 5EAUA 4JXNA 4WK5A 2ZCRA 5AYPA 4LZ0A 3P41A 3NPRA 4DI5A 3M01A 5HN8A 3DYGA 2Z4WA 2Z7IA 4LA5A 3IPIA 4RXAA 3IBAA 4OKZA 3M9UA 2AELA 2E95A 2EWGA 4RXCA 3WCCA 2PS5A 2VF6A 3AQBB 4DEMF 3KBKA 3W7FA 3WCDA 1WL0A 2OPMA 3ZL6A 1YQ7A 3SAEA 4N9UA 3N6KF 3TC1A 4LOBA 1YYSA 3LMDA 3PDEA 3LOMA 4LLSA 5B00A 2Q9YA 1HM4A 2OGDA 3PKOA 4RNQA 3S9VA 3CP6A 2Z4VA 2PS8A 2F89F 1WL1A 2E93A 3N5JF 3ICNA 4DWGA 4DXJA 1WMWA 2Z78A 4EA1A 2ZCSA 2Z50A 3ADZA 4HD1A 1UBVA 3WSBA 3Q1OA 2F94F 3SDQA 3WEGA 4JZXA 2AETA 1UBYA 2QISA 5B0KA 2Q58A 2E8UA 5DW7A 4MC3A 3OABA 5JUZF 1N1BA 4OKMA 3WSAA 5B0LA 1HXCA 5EATA 1YYTA 1VG3A 2PS7A 1YYRA 1ZW5A 3PYAA 5IN8A 5ERNA 5B02A 4KVDA 2AZLA 2Z4XA 5JV1F 1HXGA 3NPKA 4JVJF 5ER8A 3ACYA 2ZY1A 5A0JA 3KRAB 4NUAA 5DHIA 3VJEA 1YYQA 4XQTF 3TFVA 4JYXA 5B01A 3RBMA 3WJOA 3LDWA 4Q23A 4DHDA 3TFNA 3VJAA 5A0KA 3LVSA 4OMGA 5IM1A 4NFIF 3V1VA 3P8LA 3WEIA 3WE9A 3KRFB 5E8HA 3WEFA 3B7LA 5B03A 1N20A 3WCMA 1YJ4A 4KVYA 4EA2A 3ACWA 1KIZA 3ICZA 3WCHA 5IVGA 2AZJA 1WKZA 5C05A 1EZFA 3RMGA 2E8XA 3N49F 3KRAA 5A0IA 3LJIA 2ZEVA 3LZ9A 3WCFA 2ONHA 3LLWA 3N45F 1V4EA 3OYRA 4LA6A 4QXSF 3V1XA 4E1EA 5ILIA 4KUXA 1UBXA 2DH4A 4KVIA 3P5RA 4E9UA 3LK5A 4P0XA 2F9KF 3WEKA 2J1PA 5CG6A 3MZVA 1N22A 1VG7A 5AFXA 1JFGA 3S4JA 4LIXA 3DYFA 3NF2A 5DGSF 5B0MA 3EGTA 4K10A 2FTZA 4RXEA 4KPDA 4UMJA 4E9ZA 3ASXA 3OACB 3LSNA 5E8LA 4H5EF 3LEEA 3ID0A 4H5DF 1RTRA 4KVWA 4P0VA 4NKEA 2E4OA 2F8CF 5HNAA 2Z7HA 4LPGF 4LZ3A 5B0IA 5IL8A 1N23A 4F6VA 3LGZB 5EASA 1HX9A 1FPSA 1V4HA 3UCAA 1YYUA 5IMNA 3WCJA 4GP1A 1V4KA 3N5HF 5ILKA 3WCLA 2FORA 3LGKA 5DGNF 3N1WF 4DWBA 3SDTA 2OA6A 4EA0A 3EZ3A 4LFVF 3AE0A 3AQCB 2ZCQA 5EROA 2E92A 3BNYA 3WEHA 3WJKA 3OACA 2J5CA 1VG2A 2P1CA 3ACXA 5ILDA 3SDUA 4KQUA 5JA0F 1VG4A 3KRCB 2Q80A 3ICMA 5HN9A 1RQJA 4GAXA 2Z52A 5IL3A 1YHLA 1DGPA 4KFAA 5E8KA 3ZMBA 4GA3A 4F6XA 3N3LF 4LFEA 2PS6A 3G4DA 2Z4YA 1N1ZA 3G4FA 5KSXF 4MC8A 3TS7A 4NFKF 4P0WA 3QKCA 3LG5A 1DI1A 2AZKA 3ZOUA 4L2XF 4KPJA 5ILZA 3WJNA 1WL3A 5B0JA 3SDVA 3N46F 3M02A 2ZCOA 3CKEA 2I19A 2O1OA 4KQSA 1WY0A 2OPNA 2ZEUA 3Q30A 3N1VF 3KRFA 5DJPF 3EFQA 5DGMF 3PH7A 1RQIA 5JV0F 1V4JA 3VJCA 2E8TA 4OGUA 5IK9A 4F62A 3QQVA 5IKHA 1VG6A 2J1OA 4LFGA 4FP4A 3KB9A 2RAHA 3WCEA 5IK6A 4XQSF 3V66A 1YV5A 5IK0A 4OMHA 3VJ9A 4RXDA 4QPFA 5IMPA 3WEJA 5AHUB 4N1ZF 3OABB 5IMIA 3SDRA 4LPHF 5JV2F 5ILYA 1HXAA 3KROB 3AQ0A 1YHKA 3ZMCA 4GP2A 2Q9ZA 3WCIA 4KQ5A 2Z4ZA 2E90A 5AELA 5I1UA 5ERMA 5DJVF 3N0GA 1JFAA 3N0FA 4FJQA 4DZWA 3PYBA 4PVXF 5DIQF 5DZ2A 5DHKA 3M00A 1PS1A 1N21A 3WC9A 4ZQ8A 1N24A 3N3DA 5ILJA 3NRIA 4PVYF 4JZBA 3WCBA 4JXYA 2F8ZF 1KIYA 4LTVA 3TFPA 3APZA 3KROA 2F7MF 4NG6A 4MC0A 3ZCDA 5IKAA 3VJ8A 2F92F 5CG5A 3KRPB 1YHMA 2E94A 3P8RA 4LUUA 3WCAA
chains in the Genus database with same CATH topology
3WCGA 1UBWA 4H5CF 2AEKA 4NKFA 3VJDA 3Q2QA 5DJRF 3RYEA 4RYPA 4LXWA 3P5PA 4LZCA 3CC9A 3RYWA 4KWDA 2E8VA 3DYHA 2H8OA 3KRCA 3BNXA 4XQRF 5ILHA 1WL2A 2ONGA 3ICKA 2E8WA 3Q2ZA 4LTZA 4NFJF 2PS4A 2E91A 4KK2A 1V4IA 3MAVA 3VJBA 1HM7A 3M0GA 3KRPA 4KKMA 5HN7A 4LLTA 5H9DA 5EAUA 4JXNA 4WK5A 2ZCRA 5AYPA 4LZ0A 3P41A 3NPRA 4DI5A 3M01A 5HN8A 3DYGA 2Z4WA 2Z7IA 4LA5A 3IPIA 4RXAA 3IBAA 4OKZA 3M9UA 2AELA 2E95A 2EWGA 4RXCA 3WCCA 2PS5A 2VF6A 3AQBB 4DEMF 3KBKA 3W7FA 3WCDA 1WL0A 2OPMA 3ZL6A 1YQ7A 3SAEA 4N9UA 3N6KF 3TC1A 4LOBA 1YYSA 3LMDA 3PDEA 3LOMA 4LLSA 5B00A 2Q9YA 1HM4A 2OGDA 3PKOA 4RNQA 3S9VA 3CP6A 2Z4VA 2PS8A 2F89F 1WL1A 2E93A 3N5JF 3ICNA 4DWGA 4DXJA 1WMWA 2Z78A 4EA1A 2ZCSA 2Z50A 3ADZA 4HD1A 1UBVA 3WSBA 3Q1OA 2F94F 3SDQA 3WEGA 4JZXA 2AETA 1UBYA 2QISA 5B0KA 2Q58A 2E8UA 5DW7A 4MC3A 3OABA 5JUZF 1N1BA 4OKMA 3WSAA 5B0LA 1HXCA 5EATA 1YYTA 1VG3A 2PS7A 1YYRA 1ZW5A 3PYAA 5IN8A 5ERNA 5B02A 4KVDA 2AZLA 2Z4XA 5JV1F 1HXGA 3NPKA 4JVJF 5ER8A 3ACYA 2ZY1A 5A0JA 3KRAB 4NUAA 5DHIA 3VJEA 1YYQA 4XQTF 3TFVA 4JYXA 5B01A 3RBMA 3WJOA 3LDWA 4Q23A 4DHDA 3TFNA 3VJAA 5A0KA 3LVSA 4OMGA 5IM1A 4NFIF 3V1VA 3P8LA 3WEIA 3WE9A 3KRFB 5E8HA 3WEFA 3B7LA 5B03A 1N20A 3WCMA 1YJ4A 4KVYA 4EA2A 3ACWA 1KIZA 3ICZA 3WCHA 5IVGA 2AZJA 1WKZA 5C05A 1EZFA 3RMGA 2E8XA 3N49F 3KRAA 5A0IA 3LJIA 2ZEVA 3LZ9A 3WCFA 2ONHA 3LLWA 3N45F 1V4EA 3OYRA 4LA6A 4QXSF 3V1XA 4E1EA 5ILIA 4KUXA 1UBXA 2DH4A 4KVIA 3P5RA 4E9UA 3LK5A 4P0XA 2F9KF 3WEKA 2J1PA 5CG6A 3MZVA 1N22A 1VG7A 5AFXA 1JFGA 3S4JA 4LIXA 3DYFA 3NF2A 5DGSF 5B0MA 3EGTA 4K10A 2FTZA 4RXEA 4KPDA 4UMJA 4E9ZA 3ASXA 3OACB 3LSNA 5E8LA 4H5EF 3LEEA 3ID0A 4H5DF 1RTRA 4KVWA 4P0VA 4NKEA 2E4OA 2F8CF 5HNAA 2Z7HA 4LPGF 4LZ3A 5B0IA 5IL8A 1N23A 4F6VA 3LGZB 5EASA 1HX9A 1FPSA 1V4HA 3UCAA 1YYUA 5IMNA 3WCJA 4GP1A 1V4KA 3N5HF 5ILKA 3WCLA 2FORA 3LGKA 5DGNF 3N1WF 4DWBA 3SDTA 2OA6A 4EA0A 3EZ3A 4LFVF 3AE0A 3AQCB 2ZCQA 5EROA 2E92A 3BNYA 3WEHA 3WJKA 3OACA 2J5CA 1VG2A 2P1CA 3ACXA 5ILDA 3SDUA 4KQUA 5JA0F 1VG4A 3KRCB 2Q80A 3ICMA 5HN9A 1RQJA 4GAXA 2Z52A 5IL3A 1YHLA 1DGPA 4KFAA 5E8KA 3ZMBA 4GA3A 4F6XA 3N3LF 4LFEA 2PS6A 3G4DA 2Z4YA 1N1ZA 3G4FA 5KSXF 4MC8A 3TS7A 4NFKF 4P0WA 3QKCA 3LG5A 1DI1A 2AZKA 3ZOUA 4L2XF 4KPJA 5ILZA 3WJNA 1WL3A 5B0JA 3SDVA 3N46F 3M02A 2ZCOA 3CKEA 2I19A 2O1OA 4KQSA 1WY0A 2OPNA 2ZEUA 3Q30A 3N1VF 3KRFA 5DJPF 3EFQA 5DGMF 3PH7A 1RQIA 5JV0F 1V4JA 3VJCA 2E8TA 4OGUA 5IK9A 4F62A 3QQVA 5IKHA 1VG6A 2J1OA 4LFGA 4FP4A 3KB9A 2RAHA 3WCEA 5IK6A 4XQSF 3V66A 1YV5A 5IK0A 4OMHA 3VJ9A 4RXDA 4QPFA 5IMPA 3WEJA 5AHUB 4N1ZF 3OABB 5IMIA 3SDRA 4LPHF 5JV2F 5ILYA 1HXAA 3KROB 3AQ0A 1YHKA 3ZMCA 4GP2A 2Q9ZA 3WCIA 4KQ5A 2Z4ZA 2E90A 5AELA 5I1UA 5ERMA 5DJVF 3N0GA 1JFAA 3N0FA 4FJQA 4DZWA 3PYBA 4PVXF 5DIQF 5DZ2A 5DHKA 3M00A 1PS1A 1N21A 3WC9A 4ZQ8A 1N24A 3N3DA 5ILJA 3NRIA 4PVYF 4JZBA 3WCBA 4JXYA 2F8ZF 1KIYA 4LTVA 3TFPA 3APZA 3KROA 2F7MF 4NG6A 4MC0A 3ZCDA 5IKAA 3VJ8A 2F92F 5CG5A 3KRPB 1YHMA 2E94A 3P8RA 4LUUA 3WCAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WCG A;  1UBW A;  4H5C F;  2AEK A;  4NKF A;  3VJD A;  3Q2Q A;  5DJR F;  3RYE A;  4RYP A;  4LXW A;  3P5P A;  4LZC A;  3CC9 A;  3RYW A;  4KWD A;  2E8V A;  3DYH A;  2H8O A;  3KRC A;  3BNX A;  4XQR F;  5ILH A;  1WL2 A;  2ONG A;  3ICK A;  2E8W A;  3Q2Z A;  4LTZ A;  4NFJ F;  2PS4 A;  2E91 A;  4KK2 A;  1V4I A;  3MAV A;  3VJB A;  1HM7 A;  3M0G A;  3KRP A;  4KKM A;  5HN7 A;  4LLT A;  5H9D A;  5EAU A;  4JXN A;  4WK5 A;  2ZCR A;  5AYP A;  4LZ0 A;  3P41 A;  3NPR A;  4DI5 A;  3M01 A;  5HN8 A;  3DYG A;  2Z4W A;  2Z7I A;  4LA5 A;  3IPI A;  4RXA A;  3IBA A;  4OKZ A;  3M9U A;  2AEL A;  2E95 A;  2EWG A;  4RXC A;  3WCC A;  2PS5 A;  2VF6 A;  3AQB B;  4DEM F;  3KBK A;  3W7F A;  3WCD A;  1WL0 A;  2OPM A;  3ZL6 A;  1YQ7 A;  3SAE A;  4N9U A;  3N6K F;  3TC1 A;  4LOB A;  1YYS A;  3LMD A;  3PDE A;  3LOM A;  4LLS A;  5B00 A;  2Q9Y A;  1HM4 A;  2OGD A;  3PKO A;  4RNQ A;  3S9V A;  3CP6 A;  2Z4V A;  2PS8 A;  2F89 F;  1WL1 A;  2E93 A;  3N5J F;  3ICN A;  4DWG A;  4DXJ A;  1WMW A;  2Z78 A;  4EA1 A;  2ZCS A;  2Z50 A;  3ADZ A;  4HD1 A;  1UBV A;  3WSB A;  3Q1O A;  2F94 F;  3SDQ A;  3WEG A;  4JZX A;  2AET A;  1UBY A;  2QIS A;  5B0K A;  2Q58 A;  2E8U A;  5DW7 A;  4MC3 A;  3OAB A;  5JUZ F;  1N1B A;  4OKM A;  3WSA A;  5B0L A;  1HXC A;  5EAT A;  1YYT A;  1VG3 A;  2PS7 A;  1YYR A;  1ZW5 A;  3PYA A;  5IN8 A;  5ERN A;  5B02 A;  4KVD A;  2AZL A;  2Z4X A;  5JV1 F;  1HXG A;  3NPK A;  4JVJ F;  5ER8 A;  3ACY A;  2ZY1 A;  5A0J A;  3KRA B;  4NUA A;  5DHI A;  3VJE A;  1YYQ A;  4XQT F;  3TFV A;  4JYX A;  5B01 A;  3RBM A;  3WJO A;  3LDW A;  4Q23 A;  4DHD A;  3TFN A;  3VJA A;  5A0K A;  3LVS A;  4OMG A;  5IM1 A;  4NFI F;  3V1V A;  3P8L A;  3WEI A;  3WE9 A;  3KRF B;  5E8H A;  3WEF A;  3B7L A;  5B03 A;  1N20 A;  3WCM A;  1YJ4 A;  4KVY A;  4EA2 A;  3ACW A;  1KIZ A;  3ICZ A;  3WCH A;  5IVG A;  2AZJ A;  1WKZ A;  5C05 A;  1EZF A;  3RMG A;  2E8X A;  3N49 F;  3KRA A;  5A0I A;  3LJI A;  2ZEV A;  3LZ9 A;  3WCF A;  2ONH A;  3LLW A;  3N45 F;  1V4E A;  3OYR A;  4LA6 A;  4QXS F;  3V1X A;  4E1E A;  5ILI A;  4KUX A;  1UBX A;  2DH4 A;  4KVI A;  3P5R A;  4E9U A;  3LK5 A;  4P0X A;  2F9K F;  3WEK A;  2J1P A;  5CG6 A;  3MZV A;  1N22 A;  1VG7 A;  5AFX A;  1JFG A;  3S4J A;  4LIX A;  3DYF A;  3NF2 A;  5DGS F;  5B0M A;  3EGT A;  4K10 A;  2FTZ A;  4RXE A;  4KPD A;  4UMJ A;  4E9Z A;  3ASX A;  3OAC B;  3LSN A;  5E8L A;  4H5E F;  3LEE A;  3ID0 A;  4H5D F;  1RTR A;  4KVW A;  4P0V A;  4NKE A;  2E4O A;  2F8C F;  5HNA A;  2Z7H A;  4LPG F;  4LZ3 A;  5B0I A;  5IL8 A;  1N23 A;  4F6V A;  3LGZ B;  5EAS A;  1HX9 A;  1FPS A;  1V4H A;  3UCA A;  1YYU A;  5IMN A;  3WCJ A;  4GP1 A;  1V4K A;  3N5H F;  5ILK A;  3WCL A;  2FOR A;  3LGK A;  5DGN F;  3N1W F;  4DWB A;  3SDT A;  2OA6 A;  4EA0 A;  3EZ3 A;  4LFV F;  3AE0 A;  3AQC B;  2ZCQ A;  5ERO A;  2E92 A;  3BNY A;  3WEH A;  3WJK A;  3OAC A;  2J5C A;  1VG2 A;  2P1C A;  3ACX A;  5ILD A;  3SDU A;  4KQU A;  5JA0 F;  1VG4 A;  3KRC B;  2Q80 A;  3ICM A;  5HN9 A;  1RQJ A;  4GAX A;  2Z52 A;  5IL3 A;  1YHL A;  1DGP A;  4KFA A;  5E8K A;  3ZMB A;  4GA3 A;  4F6X A;  3N3L F;  4LFE A;  2PS6 A;  3G4D A;  2Z4Y A;  1N1Z A;  3G4F A;  5KSX F;  4MC8 A;  3TS7 A;  4NFK F;  4P0W A;  3QKC A;  3LG5 A;  1DI1 A;  2AZK A;  3ZOU A;  4L2X F;  4KPJ A;  5ILZ A;  3WJN A;  1WL3 A;  5B0J A;  3SDV A;  3N46 F;  3M02 A;  2ZCO A;  3CKE A;  2I19 A;  2O1O A;  4KQS A;  1WY0 A;  2OPN A;  2ZEU A;  3Q30 A;  3N1V F;  3KRF A;  5DJP F;  3EFQ A;  5DGM F;  3PH7 A;  1RQI A;  5JV0 F;  1V4J A;  3VJC A;  2E8T A;  4OGU A;  5IK9 A;  4F62 A;  3QQV A;  5IKH A;  1VG6 A;  2J1O A;  4LFG A;  4FP4 A;  3KB9 A;  2RAH A;  3WCE A;  5IK6 A;  4XQS F;  3V66 A;  1YV5 A;  5IK0 A;  4OMH A;  3VJ9 A;  4RXD A;  4QPF A;  5IMP A;  3WEJ A;  5AHU B;  4N1Z F;  3OAB B;  5IMI A;  3SDR A;  4LPH F;  5JV2 F;  5ILY A;  1HXA A;  3KRO B;  3AQ0 A;  1YHK A;  3ZMC A;  4GP2 A;  2Q9Z A;  3WCI A;  4KQ5 A;  2Z4Z A;  2E90 A;  5AEL A;  5I1U A;  5ERM A;  5DJV F;  3N0G A;  1JFA A;  3N0F A;  4FJQ A;  4DZW A;  3PYB A;  4PVX F;  5DIQ F;  5DZ2 A;  5DHK A;  3M00 A;  1PS1 A;  1N21 A;  3WC9 A;  4ZQ8 A;  1N24 A;  3N3D A;  5ILJ A;  3NRI A;  4PVY F;  4JZB A;  3WCB A;  4JXY A;  2F8Z F;  1KIY A;  4LTV A;  3TFP A;  3APZ A;  3KRO A;  2F7M F;  4NG6 A;  4MC0 A;  3ZCD A;  5IKA A;  3VJ8 A;  2F92 F;  5CG5 A;  3KRP B;  1YHM A;  2E94 A;  3P8R A;  4LUU A;  3WCA A; 
#chains in the Genus database with same CATH topology
 3WCG A;  1UBW A;  4H5C F;  2AEK A;  4NKF A;  3VJD A;  3Q2Q A;  5DJR F;  3RYE A;  4RYP A;  4LXW A;  3P5P A;  4LZC A;  3CC9 A;  3RYW A;  4KWD A;  2E8V A;  3DYH A;  2H8O A;  3KRC A;  3BNX A;  4XQR F;  5ILH A;  1WL2 A;  2ONG A;  3ICK A;  2E8W A;  3Q2Z A;  4LTZ A;  4NFJ F;  2PS4 A;  2E91 A;  4KK2 A;  1V4I A;  3MAV A;  3VJB A;  1HM7 A;  3M0G A;  3KRP A;  4KKM A;  5HN7 A;  4LLT A;  5H9D A;  5EAU A;  4JXN A;  4WK5 A;  2ZCR A;  5AYP A;  4LZ0 A;  3P41 A;  3NPR A;  4DI5 A;  3M01 A;  5HN8 A;  3DYG A;  2Z4W A;  2Z7I A;  4LA5 A;  3IPI A;  4RXA A;  3IBA A;  4OKZ A;  3M9U A;  2AEL A;  2E95 A;  2EWG A;  4RXC A;  3WCC A;  2PS5 A;  2VF6 A;  3AQB B;  4DEM F;  3KBK A;  3W7F A;  3WCD A;  1WL0 A;  2OPM A;  3ZL6 A;  1YQ7 A;  3SAE A;  4N9U A;  3N6K F;  3TC1 A;  4LOB A;  1YYS A;  3LMD A;  3PDE A;  3LOM A;  4LLS A;  5B00 A;  2Q9Y A;  1HM4 A;  2OGD A;  3PKO A;  4RNQ A;  3S9V A;  3CP6 A;  2Z4V A;  2PS8 A;  2F89 F;  1WL1 A;  2E93 A;  3N5J F;  3ICN A;  4DWG A;  4DXJ A;  1WMW A;  2Z78 A;  4EA1 A;  2ZCS A;  2Z50 A;  3ADZ A;  4HD1 A;  1UBV A;  3WSB A;  3Q1O A;  2F94 F;  3SDQ A;  3WEG A;  4JZX A;  2AET A;  1UBY A;  2QIS A;  5B0K A;  2Q58 A;  2E8U A;  5DW7 A;  4MC3 A;  3OAB A;  5JUZ F;  1N1B A;  4OKM A;  3WSA A;  5B0L A;  1HXC A;  5EAT A;  1YYT A;  1VG3 A;  2PS7 A;  1YYR A;  1ZW5 A;  3PYA A;  5IN8 A;  5ERN A;  5B02 A;  4KVD A;  2AZL A;  2Z4X A;  5JV1 F;  1HXG A;  3NPK A;  4JVJ F;  5ER8 A;  3ACY A;  2ZY1 A;  5A0J A;  3KRA B;  4NUA A;  5DHI A;  3VJE A;  1YYQ A;  4XQT F;  3TFV A;  4JYX A;  5B01 A;  3RBM A;  3WJO A;  3LDW A;  4Q23 A;  4DHD A;  3TFN A;  3VJA A;  5A0K A;  3LVS A;  4OMG A;  5IM1 A;  4NFI F;  3V1V A;  3P8L A;  3WEI A;  3WE9 A;  3KRF B;  5E8H A;  3WEF A;  3B7L A;  5B03 A;  1N20 A;  3WCM A;  1YJ4 A;  4KVY A;  4EA2 A;  3ACW A;  1KIZ A;  3ICZ A;  3WCH A;  5IVG A;  2AZJ A;  1WKZ A;  5C05 A;  1EZF A;  3RMG A;  2E8X A;  3N49 F;  3KRA A;  5A0I A;  3LJI A;  2ZEV A;  3LZ9 A;  3WCF A;  2ONH A;  3LLW A;  3N45 F;  1V4E A;  3OYR A;  4LA6 A;  4QXS F;  3V1X A;  4E1E A;  5ILI A;  4KUX A;  1UBX A;  2DH4 A;  4KVI A;  3P5R A;  4E9U A;  3LK5 A;  4P0X A;  2F9K F;  3WEK A;  2J1P A;  5CG6 A;  3MZV A;  1N22 A;  1VG7 A;  5AFX A;  1JFG A;  3S4J A;  4LIX A;  3DYF A;  3NF2 A;  5DGS F;  5B0M A;  3EGT A;  4K10 A;  2FTZ A;  4RXE A;  4KPD A;  4UMJ A;  4E9Z A;  3ASX A;  3OAC B;  3LSN A;  5E8L A;  4H5E F;  3LEE A;  3ID0 A;  4H5D F;  1RTR A;  4KVW A;  4P0V A;  4NKE A;  2E4O A;  2F8C F;  5HNA A;  2Z7H A;  4LPG F;  4LZ3 A;  5B0I A;  5IL8 A;  1N23 A;  4F6V A;  3LGZ B;  5EAS A;  1HX9 A;  1FPS A;  1V4H A;  3UCA A;  1YYU A;  5IMN A;  3WCJ A;  4GP1 A;  1V4K A;  3N5H F;  5ILK A;  3WCL A;  2FOR A;  3LGK A;  5DGN F;  3N1W F;  4DWB A;  3SDT A;  2OA6 A;  4EA0 A;  3EZ3 A;  4LFV F;  3AE0 A;  3AQC B;  2ZCQ A;  5ERO A;  2E92 A;  3BNY A;  3WEH A;  3WJK A;  3OAC A;  2J5C A;  1VG2 A;  2P1C A;  3ACX A;  5ILD A;  3SDU A;  4KQU A;  5JA0 F;  1VG4 A;  3KRC B;  2Q80 A;  3ICM A;  5HN9 A;  1RQJ A;  4GAX A;  2Z52 A;  5IL3 A;  1YHL A;  1DGP A;  4KFA A;  5E8K A;  3ZMB A;  4GA3 A;  4F6X A;  3N3L F;  4LFE A;  2PS6 A;  3G4D A;  2Z4Y A;  1N1Z A;  3G4F A;  5KSX F;  4MC8 A;  3TS7 A;  4NFK F;  4P0W A;  3QKC A;  3LG5 A;  1DI1 A;  2AZK A;  3ZOU A;  4L2X F;  4KPJ A;  5ILZ A;  3WJN A;  1WL3 A;  5B0J A;  3SDV A;  3N46 F;  3M02 A;  2ZCO A;  3CKE A;  2I19 A;  2O1O A;  4KQS A;  1WY0 A;  2OPN A;  2ZEU A;  3Q30 A;  3N1V F;  3KRF A;  5DJP F;  3EFQ A;  5DGM F;  3PH7 A;  1RQI A;  5JV0 F;  1V4J A;  3VJC A;  2E8T A;  4OGU A;  5IK9 A;  4F62 A;  3QQV A;  5IKH A;  1VG6 A;  2J1O A;  4LFG A;  4FP4 A;  3KB9 A;  2RAH A;  3WCE A;  5IK6 A;  4XQS F;  3V66 A;  1YV5 A;  5IK0 A;  4OMH A;  3VJ9 A;  4RXD A;  4QPF A;  5IMP A;  3WEJ A;  5AHU B;  4N1Z F;  3OAB B;  5IMI A;  3SDR A;  4LPH F;  5JV2 F;  5ILY A;  1HXA A;  3KRO B;  3AQ0 A;  1YHK A;  3ZMC A;  4GP2 A;  2Q9Z A;  3WCI A;  4KQ5 A;  2Z4Z A;  2E90 A;  5AEL A;  5I1U A;  5ERM A;  5DJV F;  3N0G A;  1JFA A;  3N0F A;  4FJQ A;  4DZW A;  3PYB A;  4PVX F;  5DIQ F;  5DZ2 A;  5DHK A;  3M00 A;  1PS1 A;  1N21 A;  3WC9 A;  4ZQ8 A;  1N24 A;  3N3D A;  5ILJ A;  3NRI A;  4PVY F;  4JZB A;  3WCB A;  4JXY A;  2F8Z F;  1KIY A;  4LTV A;  3TFP A;  3APZ A;  3KRO A;  2F7M F;  4NG6 A;  4MC0 A;  3ZCD A;  5IKA A;  3VJ8 A;  2F92 F;  5CG5 A;  3KRP B;  1YHM A;  2E94 A;  3P8R A;  4LUU A;  3WCA A; 
#chains in the Genus database with same CATH homology
 3WCG A;  1UBW A;  4H5C F;  2AEK A;  4NKF A;  3VJD A;  3Q2Q A;  5DJR F;  3RYE A;  4RYP A;  4LXW A;  3P5P A;  4LZC A;  3CC9 A;  3RYW A;  4KWD A;  2E8V A;  3DYH A;  2H8O A;  3KRC A;  3BNX A;  4XQR F;  5ILH A;  1WL2 A;  2ONG A;  3ICK A;  2E8W A;  3Q2Z A;  4LTZ A;  4NFJ F;  2PS4 A;  2E91 A;  4KK2 A;  1V4I A;  3MAV A;  3VJB A;  1HM7 A;  3M0G A;  3KRP A;  4KKM A;  5HN7 A;  4LLT A;  5H9D A;  5EAU A;  4JXN A;  4WK5 A;  2ZCR A;  5AYP A;  4LZ0 A;  3P41 A;  3NPR A;  4DI5 A;  3M01 A;  5HN8 A;  3DYG A;  2Z4W A;  2Z7I A;  4LA5 A;  3IPI A;  4RXA A;  3IBA A;  4OKZ A;  3M9U A;  2AEL A;  2E95 A;  2EWG A;  4RXC A;  3WCC A;  2PS5 A;  2VF6 A;  3AQB B;  4DEM F;  3KBK A;  3W7F A;  3WCD A;  1WL0 A;  2OPM A;  3ZL6 A;  1YQ7 A;  3SAE A;  4N9U A;  3N6K F;  3TC1 A;  4LOB A;  1YYS A;  3LMD A;  3PDE A;  3LOM A;  4LLS A;  5B00 A;  2Q9Y A;  1HM4 A;  2OGD A;  3PKO A;  4RNQ A;  3S9V A;  3CP6 A;  2Z4V A;  2PS8 A;  2F89 F;  1WL1 A;  2E93 A;  3N5J F;  3ICN A;  4DWG A;  4DXJ A;  1WMW A;  2Z78 A;  4EA1 A;  2ZCS A;  2Z50 A;  3ADZ A;  4HD1 A;  1UBV A;  3WSB A;  3Q1O A;  2F94 F;  3SDQ A;  3WEG A;  4JZX A;  2AET A;  1UBY A;  2QIS A;  5B0K A;  2Q58 A;  2E8U A;  5DW7 A;  4MC3 A;  3OAB A;  5JUZ F;  1N1B A;  4OKM A;  3WSA A;  5B0L A;  1HXC A;  5EAT A;  1YYT A;  1VG3 A;  2PS7 A;  1YYR A;  1ZW5 A;  3PYA A;  5IN8 A;  5ERN A;  5B02 A;  4KVD A;  2AZL A;  2Z4X A;  5JV1 F;  1HXG A;  3NPK A;  4JVJ F;  5ER8 A;  3ACY A;  2ZY1 A;  5A0J A;  3KRA B;  4NUA A;  5DHI A;  3VJE A;  1YYQ A;  4XQT F;  3TFV A;  4JYX A;  5B01 A;  3RBM A;  3WJO A;  3LDW A;  4Q23 A;  4DHD A;  3TFN A;  3VJA A;  5A0K A;  3LVS A;  4OMG A;  5IM1 A;  4NFI F;  3V1V A;  3P8L A;  3WEI A;  3WE9 A;  3KRF B;  5E8H A;  3WEF A;  3B7L A;  5B03 A;  1N20 A;  3WCM A;  1YJ4 A;  4KVY A;  4EA2 A;  3ACW A;  1KIZ A;  3ICZ A;  3WCH A;  5IVG A;  2AZJ A;  1WKZ A;  5C05 A;  1EZF A;  3RMG A;  2E8X A;  3N49 F;  3KRA A;  5A0I A;  3LJI A;  2ZEV A;  3LZ9 A;  3WCF A;  2ONH A;  3LLW A;  3N45 F;  1V4E A;  3OYR A;  4LA6 A;  4QXS F;  3V1X A;  4E1E A;  5ILI A;  4KUX A;  1UBX A;  2DH4 A;  4KVI A;  3P5R A;  4E9U A;  3LK5 A;  4P0X A;  2F9K F;  3WEK A;  2J1P A;  5CG6 A;  3MZV A;  1N22 A;  1VG7 A;  5AFX A;  1JFG A;  3S4J A;  4LIX A;  3DYF A;  3NF2 A;  5DGS F;  5B0M A;  3EGT A;  4K10 A;  2FTZ A;  4RXE A;  4KPD A;  4UMJ A;  4E9Z A;  3ASX A;  3OAC B;  3LSN A;  5E8L A;  4H5E F;  3LEE A;  3ID0 A;  4H5D F;  1RTR A;  4KVW A;  4P0V A;  4NKE A;  2E4O A;  2F8C F;  5HNA A;  2Z7H A;  4LPG F;  4LZ3 A;  5B0I A;  5IL8 A;  1N23 A;  4F6V A;  3LGZ B;  5EAS A;  1HX9 A;  1FPS A;  1V4H A;  3UCA A;  1YYU A;  5IMN A;  3WCJ A;  4GP1 A;  1V4K A;  3N5H F;  5ILK A;  3WCL A;  2FOR A;  3LGK A;  5DGN F;  3N1W F;  4DWB A;  3SDT A;  2OA6 A;  4EA0 A;  3EZ3 A;  4LFV F;  3AE0 A;  3AQC B;  2ZCQ A;  5ERO A;  2E92 A;  3BNY A;  3WEH A;  3WJK A;  3OAC A;  2J5C A;  1VG2 A;  2P1C A;  3ACX A;  5ILD A;  3SDU A;  4KQU A;  5JA0 F;  1VG4 A;  3KRC B;  2Q80 A;  3ICM A;  5HN9 A;  1RQJ A;  4GAX A;  2Z52 A;  5IL3 A;  1YHL A;  1DGP A;  4KFA A;  5E8K A;  3ZMB A;  4GA3 A;  4F6X A;  3N3L F;  4LFE A;  2PS6 A;  3G4D A;  2Z4Y A;  1N1Z A;  3G4F A;  5KSX F;  4MC8 A;  3TS7 A;  4NFK F;  4P0W A;  3QKC A;  3LG5 A;  1DI1 A;  2AZK A;  3ZOU A;  4L2X F;  4KPJ A;  5ILZ A;  3WJN A;  1WL3 A;  5B0J A;  3SDV A;  3N46 F;  3M02 A;  2ZCO A;  3CKE A;  2I19 A;  2O1O A;  4KQS A;  1WY0 A;  2OPN A;  2ZEU A;  3Q30 A;  3N1V F;  3KRF A;  5DJP F;  3EFQ A;  5DGM F;  3PH7 A;  1RQI A;  5JV0 F;  1V4J A;  3VJC A;  2E8T A;  4OGU A;  5IK9 A;  4F62 A;  3QQV A;  5IKH A;  1VG6 A;  2J1O A;  4LFG A;  4FP4 A;  3KB9 A;  2RAH A;  3WCE A;  5IK6 A;  4XQS F;  3V66 A;  1YV5 A;  5IK0 A;  4OMH A;  3VJ9 A;  4RXD A;  4QPF A;  5IMP A;  3WEJ A;  5AHU B;  4N1Z F;  3OAB B;  5IMI A;  3SDR A;  4LPH F;  5JV2 F;  5ILY A;  1HXA A;  3KRO B;  3AQ0 A;  1YHK A;  3ZMC A;  4GP2 A;  2Q9Z A;  3WCI A;  4KQ5 A;  2Z4Z A;  2E90 A;  5AEL A;  5I1U A;  5ERM A;  5DJV F;  3N0G A;  1JFA A;  3N0F A;  4FJQ A;  4DZW A;  3PYB A;  4PVX F;  5DIQ F;  5DZ2 A;  5DHK A;  3M00 A;  1PS1 A;  1N21 A;  3WC9 A;  4ZQ8 A;  1N24 A;  3N3D A;  5ILJ A;  3NRI A;  4PVY F;  4JZB A;  3WCB A;  4JXY A;  2F8Z F;  1KIY A;  4LTV A;  3TFP A;  3APZ A;  3KRO A;  2F7M F;  4NG6 A;  4MC0 A;  3ZCD A;  5IKA A;  3VJ8 A;  2F92 F;  5CG5 A;  3KRP B;  1YHM A;  2E94 A;  3P8R A;  4LUU A;  3WCA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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