4JVJF

Crystal structure of human fpps in complex with magnesium, cl01131, and sulfate
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Farnesyl pyrophosphate synthase
total genus 130
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4jvjF00
2PS6A 1YYUA 4JYXA 4KKMA 3AQBB 3LMDA 1VG7A 2F92F 3WCIA 3RMGA 4ZQ8A 1RQJA 5HNAA 3KRPA 5B0IA 1N1ZA 5IK6A 2Q9ZA 2J5CA 2OGDA 4KQUA 4KPJA 4OMGA 5A0IA 3CC9A 5B00A 3OACA 4F62A 1PS1A 1YHLA 5A0JA 1EZFA 4LLTA 1WKZA 3WEHA 3VJBA 2Z4ZA 4RXAA 1WY0A 3ADZA 3WCAA 3Q2QA 1N20A 4QPFA 4NFJF 1V4EA 3ZMCA 1HX9A 5B0JA 2Z50A 3WCJA 3V66A 2FTZA 3LZ9A 3LEEA 3KRPB 3TS7A 5B0MA 3WCBA 4RYPA 4LA5A 1VG6A 2QISA 2E90A 3NPRA 4LPGF 5ER8A 3SDTA 5IL8A 5ILKA 3LG5A 3N3LF 3WEIA 3LOMA 4OKZA 3OACB 3S4JA 5A0KA 2EWGA 3SDQA 2ONHA 1V4JA 1JFAA 3QKCA 5ILIA 3W7FA 4KK2A 1N24A 3QQVA 3LJIA 5DIQF 3RYEA 5B02A 3LGKA 3SDRA 3G4DA 4JXNA 4XQSF 1V4HA 3N3DA 3N5JF 1YHMA 3WCGA 5DGSF 3UCAA 3WSAA 3WCDA 4H5CF 3PYBA 3VJ8A 2F9KF 1RQIA 3LLWA 3TC1A 2RAHA 4HD1A 1WL3A 3NF2A 3ZMBA 4KWDA 2ONGA 4E9ZA 3WCHA 5DJPF 3TFPA 5IK0A 4WK5A 1YYRA 1YHKA 3AE0A 5EROA 5DW7A 5IVGA 3APZA 3ASXA 3ICKA 1FPSA 1YJ4A 3KRFA 3NRIA 3P8LA 2DH4A 2PS8A 3B7LA 5C05A 4KPDA 2H8OA 4NG6A 2Z78A 4MC3A 3P5RA 3LSNA 4GA3A 2E8WA 5E8KA 1YQ7A 2ZCOA 4P0VA 3P41A 2ZEVA 3VJDA 4GP1A 3P5PA 2Z4XA 4XQRF 1ZW5A 1VG2A 3N0FA 3PKOA 3WC9A 3Q2ZA 1HXGA 3V1XA 4NFIF 1YYTA 3KBKA 5AFXA 4LA6A 1WL2A 2Z7HA 3DYFA 1WMWA 5AHUB 5HN9A 3WJOA 5EASA 5B01A 3KRFB 3DYGA 3BNXA 3KRAA 4F6XA 2I19A 4KVYA 3N49F 2E8TA 5E8HA 2AZKA 2E92A 5IMNA 4JZBA 5IN8A 4DWBA 5KSXF 4LZ3A 3ACXA 2PS7A 5JV0F 3Q30A 4DWGA 3CKEA 1N22A 5IL3A 2AELA 2ZY1A 4N1ZF 4NKEA 2VF6A 4NFKF 2ZEUA 5ILYA 3N46F 3WJNA 4LFGA 3OYRA 4PVXF 3ZCDA 3PYAA 2F7MF 5B0LA 1KIZA 4DI5A 4DEMF 4RXEA 2AZLA 2OA6A 1YV5A 3IBAA 1JFGA 5CG5A 3M01A 3KRAB 4MC8A 5IK9A 1KIYA 3P8RA 3M9UA 2AETA 2Q80A 3KROA 3N0GA 5IKHA 1HM4A 4LTZA 3WE9A 3ICMA 1VG4A 5B0KA 3VJCA 3RYWA 3DYHA 5ILJA 2E8VA 3CP6A 2E8UA 1V4KA 3ZOUA 3WCEA 1N21A 3BNYA 3WJKA 5EATA 3KROB 5ILDA 3N1WF 5EAUA 4LLSA 3VJAA 2ZCSA 2AEKA 2Q9YA 4DXJA 2E93A 2F8CF 5ILHA 4H5EF 4RNQA 2F8ZF 5AYPA 1DI1A 4KQSA 3TFNA 1HM7A 2PS5A 3LGZB 5DGNF 5IKAA 4MC0A 3ACYA 5HN7A 4KVDA 1V4IA 3EZ3A 2Z52A 4FJQA 1UBWA 3N6KF 1YYQA 3EGTA 5AELA 3SDVA 2Z4YA 2O1OA 2E4OA 4F6VA 3ID0A 4LPHF 3WSBA 5JA0F 5JV2F 3WEGA 5B03A 3ICNA 3TFVA 2ZCQA 3RBMA 1YYSA 2Z4VA 3V1VA 4L2XF 4QXSF 2Q58A 5DJVF 2F89F 3N1VF 1N1BA 3IPIA 3VJ9A 3OABA 4XQTF 3AQCB 3PDEA 4LZ0A 4LXWA 5I1UA 5ERNA 4PVYF 3LVSA 3MAVA 5DJRF 2AZJA 4DHDA 3SDUA 1UBXA 5CG6A 3KRCA 4OKMA 3EFQA 3ICZA 4KVWA 3WCCA 3WCFA 3VJEA 1HXCA 2E94A 4OGUA 4LZCA 5ERMA 4EA2A 3G4FA 1WL1A 4KVIA 3WEKA 4EA0A 5DGMF 2Z7IA 5IMPA 4NUAA 3M02A 3OABB 4K10A 2J1PA 1RTRA 4LIXA 3ZL6A 4LTVA 2PS4A 5DHIA 1N23A 4LFVF 2FORA 4DZWA 4RXDA 4JZXA 4H5DF 4NKFA 3LK5A 3M00A 3KRCB 3NPKA 3ACWA 3N45F 4GAXA 5JV1F 3LDWA 3WEJA 2OPMA 2E91A 3MZVA 1HXAA 4KQ5A 1DGPA 2OPNA 2E95A 4OMHA 2ZCRA 4KUXA 5IMIA 1UBVA 4RXCA 3WEFA 5HN8A 2E8XA 4P0XA 5DZ2A 4P0WA 5JUZF 4N9UA 1VG3A 3KB9A 5E8LA 4UMJA 4JVJF 2P1CA 5IM1A 3S9VA 4JXYA 3PH7A 4LOBA 4LUUA 4KFAA 4EA1A 5DHKA 4FP4A 1UBYA 3N5HF 4Q23A 3M0GA 1WL0A 2J1OA 3Q1OA 3WCMA 3WCLA 4LFEA 3AQ0A 3SAEA 2Z4WA 2F94F 4GP2A 5H9DA 4E1EA 4E9UA 5ILZA
chains in the Genus database with same CATH superfamily
2PS6A 1YYUA 4JYXA 4KKMA 3AQBB 3LMDA 1VG7A 2F92F 3WCIA 3RMGA 4ZQ8A 1RQJA 5HNAA 3KRPA 5B0IA 1N1ZA 5IK6A 2Q9ZA 2J5CA 2OGDA 4KQUA 4KPJA 4OMGA 5A0IA 3CC9A 5B00A 3OACA 4F62A 1PS1A 1YHLA 5A0JA 1EZFA 4LLTA 1WKZA 3WEHA 3VJBA 2Z4ZA 4RXAA 1WY0A 3ADZA 3WCAA 3Q2QA 1N20A 4QPFA 4NFJF 1V4EA 3ZMCA 1HX9A 5B0JA 2Z50A 3WCJA 3V66A 2FTZA 3LZ9A 3LEEA 3KRPB 3TS7A 5B0MA 3WCBA 4RYPA 4LA5A 1VG6A 2QISA 2E90A 3NPRA 4LPGF 5ER8A 3SDTA 5IL8A 5ILKA 3LG5A 3N3LF 3WEIA 3LOMA 4OKZA 3OACB 3S4JA 5A0KA 2EWGA 3SDQA 2ONHA 1V4JA 1JFAA 3QKCA 5ILIA 3W7FA 4KK2A 1N24A 3QQVA 3LJIA 5DIQF 3RYEA 5B02A 3LGKA 3SDRA 3G4DA 4JXNA 4XQSF 1V4HA 3N3DA 3N5JF 1YHMA 3WCGA 5DGSF 3UCAA 3WSAA 3WCDA 4H5CF 3PYBA 3VJ8A 2F9KF 1RQIA 3LLWA 3TC1A 2RAHA 4HD1A 1WL3A 3NF2A 3ZMBA 4KWDA 2ONGA 4E9ZA 3WCHA 5DJPF 3TFPA 5IK0A 4WK5A 1YYRA 1YHKA 3AE0A 5EROA 5DW7A 5IVGA 3APZA 3ASXA 3ICKA 1FPSA 1YJ4A 3KRFA 3NRIA 3P8LA 2DH4A 2PS8A 3B7LA 5C05A 4KPDA 2H8OA 4NG6A 2Z78A 4MC3A 3P5RA 3LSNA 4GA3A 2E8WA 5E8KA 1YQ7A 2ZCOA 4P0VA 3P41A 2ZEVA 3VJDA 4GP1A 3P5PA 2Z4XA 4XQRF 1ZW5A 1VG2A 3N0FA 3PKOA 3WC9A 3Q2ZA 1HXGA 3V1XA 4NFIF 1YYTA 3KBKA 5AFXA 4LA6A 1WL2A 2Z7HA 3DYFA 1WMWA 5AHUB 5HN9A 3WJOA 5EASA 5B01A 3KRFB 3DYGA 3BNXA 3KRAA 4F6XA 2I19A 4KVYA 3N49F 2E8TA 5E8HA 2AZKA 2E92A 5IMNA 4JZBA 5IN8A 4DWBA 5KSXF 4LZ3A 3ACXA 2PS7A 5JV0F 3Q30A 4DWGA 3CKEA 1N22A 5IL3A 2AELA 2ZY1A 4N1ZF 4NKEA 2VF6A 4NFKF 2ZEUA 5ILYA 3N46F 3WJNA 4LFGA 3OYRA 4PVXF 3ZCDA 3PYAA 2F7MF 5B0LA 1KIZA 4DI5A 4DEMF 4RXEA 2AZLA 2OA6A 1YV5A 3IBAA 1JFGA 5CG5A 3M01A 3KRAB 4MC8A 5IK9A 1KIYA 3P8RA 3M9UA 2AETA 2Q80A 3KROA 3N0GA 5IKHA 1HM4A 4LTZA 3WE9A 3ICMA 1VG4A 5B0KA 3VJCA 3RYWA 3DYHA 5ILJA 2E8VA 3CP6A 2E8UA 1V4KA 3ZOUA 3WCEA 1N21A 3BNYA 3WJKA 5EATA 3KROB 5ILDA 3N1WF 5EAUA 4LLSA 3VJAA 2ZCSA 2AEKA 2Q9YA 4DXJA 2E93A 2F8CF 5ILHA 4H5EF 4RNQA 2F8ZF 5AYPA 1DI1A 4KQSA 3TFNA 1HM7A 2PS5A 3LGZB 5DGNF 5IKAA 4MC0A 3ACYA 5HN7A 4KVDA 1V4IA 3EZ3A 2Z52A 4FJQA 1UBWA 3N6KF 1YYQA 3EGTA 5AELA 3SDVA 2Z4YA 2O1OA 2E4OA 4F6VA 3ID0A 4LPHF 3WSBA 5JA0F 5JV2F 3WEGA 5B03A 3ICNA 3TFVA 2ZCQA 3RBMA 1YYSA 2Z4VA 3V1VA 4L2XF 4QXSF 2Q58A 5DJVF 2F89F 3N1VF 1N1BA 3IPIA 3VJ9A 3OABA 4XQTF 3AQCB 3PDEA 4LZ0A 4LXWA 5I1UA 5ERNA 4PVYF 3LVSA 3MAVA 5DJRF 2AZJA 4DHDA 3SDUA 1UBXA 5CG6A 3KRCA 4OKMA 3EFQA 3ICZA 4KVWA 3WCCA 3WCFA 3VJEA 1HXCA 2E94A 4OGUA 4LZCA 5ERMA 4EA2A 3G4FA 1WL1A 4KVIA 3WEKA 4EA0A 5DGMF 2Z7IA 5IMPA 4NUAA 3M02A 3OABB 4K10A 2J1PA 1RTRA 4LIXA 3ZL6A 4LTVA 2PS4A 5DHIA 1N23A 4LFVF 2FORA 4DZWA 4RXDA 4JZXA 4H5DF 4NKFA 3LK5A 3M00A 3KRCB 3NPKA 3ACWA 3N45F 4GAXA 5JV1F 3LDWA 3WEJA 2OPMA 2E91A 3MZVA 1HXAA 4KQ5A 1DGPA 2OPNA 2E95A 4OMHA 2ZCRA 4KUXA 5IMIA 1UBVA 4RXCA 3WEFA 5HN8A 2E8XA 4P0XA 5DZ2A 4P0WA 5JUZF 4N9UA 1VG3A 3KB9A 5E8LA 4UMJA 4JVJF 2P1CA 5IM1A 3S9VA 4JXYA 3PH7A 4LOBA 4LUUA 4KFAA 4EA1A 5DHKA 4FP4A 1UBYA 3N5HF 4Q23A 3M0GA 1WL0A 2J1OA 3Q1OA 3WCMA 3WCLA 4LFEA 3AQ0A 3SAEA 2Z4WA 2F94F 4GP2A 5H9DA 4E1EA 4E9UA 5ILZA
chains in the Genus database with same CATH topology
2PS6A 1YYUA 4JYXA 4KKMA 3AQBB 3LMDA 1VG7A 2F92F 3WCIA 3RMGA 4ZQ8A 1RQJA 5HNAA 3KRPA 5B0IA 1N1ZA 5IK6A 2Q9ZA 2J5CA 2OGDA 4KQUA 4KPJA 4OMGA 5A0IA 3CC9A 5B00A 3OACA 4F62A 1PS1A 1YHLA 5A0JA 1EZFA 4LLTA 1WKZA 3WEHA 3VJBA 2Z4ZA 4RXAA 1WY0A 3ADZA 3WCAA 3Q2QA 1N20A 4QPFA 4NFJF 1V4EA 3ZMCA 1HX9A 5B0JA 2Z50A 3WCJA 3V66A 2FTZA 3LZ9A 3LEEA 3KRPB 3TS7A 5B0MA 3WCBA 4RYPA 4LA5A 1VG6A 2QISA 2E90A 3NPRA 4LPGF 5ER8A 3SDTA 5IL8A 5ILKA 3LG5A 3N3LF 3WEIA 3LOMA 4OKZA 3OACB 3S4JA 5A0KA 2EWGA 3SDQA 2ONHA 1V4JA 1JFAA 3QKCA 5ILIA 3W7FA 4KK2A 1N24A 3QQVA 3LJIA 5DIQF 3RYEA 5B02A 3LGKA 3SDRA 3G4DA 4JXNA 4XQSF 1V4HA 3N3DA 3N5JF 1YHMA 3WCGA 5DGSF 3UCAA 3WSAA 3WCDA 4H5CF 3PYBA 3VJ8A 2F9KF 1RQIA 3LLWA 3TC1A 2RAHA 4HD1A 1WL3A 3NF2A 3ZMBA 4KWDA 2ONGA 4E9ZA 3WCHA 5DJPF 3TFPA 5IK0A 4WK5A 1YYRA 1YHKA 3AE0A 5EROA 5DW7A 5IVGA 3APZA 3ASXA 3ICKA 1FPSA 1YJ4A 3KRFA 3NRIA 3P8LA 2DH4A 2PS8A 3B7LA 5C05A 4KPDA 2H8OA 4NG6A 2Z78A 4MC3A 3P5RA 3LSNA 4GA3A 2E8WA 5E8KA 1YQ7A 2ZCOA 4P0VA 3P41A 2ZEVA 3VJDA 4GP1A 3P5PA 2Z4XA 4XQRF 1ZW5A 1VG2A 3N0FA 3PKOA 3WC9A 3Q2ZA 1HXGA 3V1XA 4NFIF 1YYTA 3KBKA 5AFXA 4LA6A 1WL2A 2Z7HA 3DYFA 1WMWA 5AHUB 5HN9A 3WJOA 5EASA 5B01A 3KRFB 3DYGA 3BNXA 3KRAA 4F6XA 2I19A 4KVYA 3N49F 2E8TA 5E8HA 2AZKA 2E92A 5IMNA 4JZBA 5IN8A 4DWBA 5KSXF 4LZ3A 3ACXA 2PS7A 5JV0F 3Q30A 4DWGA 3CKEA 1N22A 5IL3A 2AELA 2ZY1A 4N1ZF 4NKEA 2VF6A 4NFKF 2ZEUA 5ILYA 3N46F 3WJNA 4LFGA 3OYRA 4PVXF 3ZCDA 3PYAA 2F7MF 5B0LA 1KIZA 4DI5A 4DEMF 4RXEA 2AZLA 2OA6A 1YV5A 3IBAA 1JFGA 5CG5A 3M01A 3KRAB 4MC8A 5IK9A 1KIYA 3P8RA 3M9UA 2AETA 2Q80A 3KROA 3N0GA 5IKHA 1HM4A 4LTZA 3WE9A 3ICMA 1VG4A 5B0KA 3VJCA 3RYWA 3DYHA 5ILJA 2E8VA 3CP6A 2E8UA 1V4KA 3ZOUA 3WCEA 1N21A 3BNYA 3WJKA 5EATA 3KROB 5ILDA 3N1WF 5EAUA 4LLSA 3VJAA 2ZCSA 2AEKA 2Q9YA 4DXJA 2E93A 2F8CF 5ILHA 4H5EF 4RNQA 2F8ZF 5AYPA 1DI1A 4KQSA 3TFNA 1HM7A 2PS5A 3LGZB 5DGNF 5IKAA 4MC0A 3ACYA 5HN7A 4KVDA 1V4IA 3EZ3A 2Z52A 4FJQA 1UBWA 3N6KF 1YYQA 3EGTA 5AELA 3SDVA 2Z4YA 2O1OA 2E4OA 4F6VA 3ID0A 4LPHF 3WSBA 5JA0F 5JV2F 3WEGA 5B03A 3ICNA 3TFVA 2ZCQA 3RBMA 1YYSA 2Z4VA 3V1VA 4L2XF 4QXSF 2Q58A 5DJVF 2F89F 3N1VF 1N1BA 3IPIA 3VJ9A 3OABA 4XQTF 3AQCB 3PDEA 4LZ0A 4LXWA 5I1UA 5ERNA 4PVYF 3LVSA 3MAVA 5DJRF 2AZJA 4DHDA 3SDUA 1UBXA 5CG6A 3KRCA 4OKMA 3EFQA 3ICZA 4KVWA 3WCCA 3WCFA 3VJEA 1HXCA 2E94A 4OGUA 4LZCA 5ERMA 4EA2A 3G4FA 1WL1A 4KVIA 3WEKA 4EA0A 5DGMF 2Z7IA 5IMPA 4NUAA 3M02A 3OABB 4K10A 2J1PA 1RTRA 4LIXA 3ZL6A 4LTVA 2PS4A 5DHIA 1N23A 4LFVF 2FORA 4DZWA 4RXDA 4JZXA 4H5DF 4NKFA 3LK5A 3M00A 3KRCB 3NPKA 3ACWA 3N45F 4GAXA 5JV1F 3LDWA 3WEJA 2OPMA 2E91A 3MZVA 1HXAA 4KQ5A 1DGPA 2OPNA 2E95A 4OMHA 2ZCRA 4KUXA 5IMIA 1UBVA 4RXCA 3WEFA 5HN8A 2E8XA 4P0XA 5DZ2A 4P0WA 5JUZF 4N9UA 1VG3A 3KB9A 5E8LA 4UMJA 4JVJF 2P1CA 5IM1A 3S9VA 4JXYA 3PH7A 4LOBA 4LUUA 4KFAA 4EA1A 5DHKA 4FP4A 1UBYA 3N5HF 4Q23A 3M0GA 1WL0A 2J1OA 3Q1OA 3WCMA 3WCLA 4LFEA 3AQ0A 3SAEA 2Z4WA 2F94F 4GP2A 5H9DA 4E1EA 4E9UA 5ILZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PS6 A;  1YYU A;  4JYX A;  4KKM A;  3AQB B;  3LMD A;  1VG7 A;  2F92 F;  3WCI A;  3RMG A;  4ZQ8 A;  1RQJ A;  5HNA A;  3KRP A;  5B0I A;  1N1Z A;  5IK6 A;  2Q9Z A;  2J5C A;  2OGD A;  4KQU A;  4KPJ A;  4OMG A;  5A0I A;  3CC9 A;  5B00 A;  3OAC A;  4F62 A;  1PS1 A;  1YHL A;  5A0J A;  1EZF A;  4LLT A;  1WKZ A;  3WEH A;  3VJB A;  2Z4Z A;  4RXA A;  1WY0 A;  3ADZ A;  3WCA A;  3Q2Q A;  1N20 A;  4QPF A;  4NFJ F;  1V4E A;  3ZMC A;  1HX9 A;  5B0J A;  2Z50 A;  3WCJ A;  3V66 A;  2FTZ A;  3LZ9 A;  3LEE A;  3KRP B;  3TS7 A;  5B0M A;  3WCB A;  4RYP A;  4LA5 A;  1VG6 A;  2QIS A;  2E90 A;  3NPR A;  4LPG F;  5ER8 A;  3SDT A;  5IL8 A;  5ILK A;  3LG5 A;  3N3L F;  3WEI A;  3LOM A;  4OKZ A;  3OAC B;  3S4J A;  5A0K A;  2EWG A;  3SDQ A;  2ONH A;  1V4J A;  1JFA A;  3QKC A;  5ILI A;  3W7F A;  4KK2 A;  1N24 A;  3QQV A;  3LJI A;  5DIQ F;  3RYE A;  5B02 A;  3LGK A;  3SDR A;  3G4D A;  4JXN A;  4XQS F;  1V4H A;  3N3D A;  3N5J F;  1YHM A;  3WCG A;  5DGS F;  3UCA A;  3WSA A;  3WCD A;  4H5C F;  3PYB A;  3VJ8 A;  2F9K F;  1RQI A;  3LLW A;  3TC1 A;  2RAH A;  4HD1 A;  1WL3 A;  3NF2 A;  3ZMB A;  4KWD A;  2ONG A;  4E9Z A;  3WCH A;  5DJP F;  3TFP A;  5IK0 A;  4WK5 A;  1YYR A;  1YHK A;  3AE0 A;  5ERO A;  5DW7 A;  5IVG A;  3APZ A;  3ASX A;  3ICK A;  1FPS A;  1YJ4 A;  3KRF A;  3NRI A;  3P8L A;  2DH4 A;  2PS8 A;  3B7L A;  5C05 A;  4KPD A;  2H8O A;  4NG6 A;  2Z78 A;  4MC3 A;  3P5R A;  3LSN A;  4GA3 A;  2E8W A;  5E8K A;  1YQ7 A;  2ZCO A;  4P0V A;  3P41 A;  2ZEV A;  3VJD A;  4GP1 A;  3P5P A;  2Z4X A;  4XQR F;  1ZW5 A;  1VG2 A;  3N0F A;  3PKO A;  3WC9 A;  3Q2Z A;  1HXG A;  3V1X A;  4NFI F;  1YYT A;  3KBK A;  5AFX A;  4LA6 A;  1WL2 A;  2Z7H A;  3DYF A;  1WMW A;  5AHU B;  5HN9 A;  3WJO A;  5EAS A;  5B01 A;  3KRF B;  3DYG A;  3BNX A;  3KRA A;  4F6X A;  2I19 A;  4KVY A;  3N49 F;  2E8T A;  5E8H A;  2AZK A;  2E92 A;  5IMN A;  4JZB A;  5IN8 A;  4DWB A;  5KSX F;  4LZ3 A;  3ACX A;  2PS7 A;  5JV0 F;  3Q30 A;  4DWG A;  3CKE A;  1N22 A;  5IL3 A;  2AEL A;  2ZY1 A;  4N1Z F;  4NKE A;  2VF6 A;  4NFK F;  2ZEU A;  5ILY A;  3N46 F;  3WJN A;  4LFG A;  3OYR A;  4PVX F;  3ZCD A;  3PYA A;  2F7M F;  5B0L A;  1KIZ A;  4DI5 A;  4DEM F;  4RXE A;  2AZL A;  2OA6 A;  1YV5 A;  3IBA A;  1JFG A;  5CG5 A;  3M01 A;  3KRA B;  4MC8 A;  5IK9 A;  1KIY A;  3P8R A;  3M9U A;  2AET A;  2Q80 A;  3KRO A;  3N0G A;  5IKH A;  1HM4 A;  4LTZ A;  3WE9 A;  3ICM A;  1VG4 A;  5B0K A;  3VJC A;  3RYW A;  3DYH A;  5ILJ A;  2E8V A;  3CP6 A;  2E8U A;  1V4K A;  3ZOU A;  3WCE A;  1N21 A;  3BNY A;  3WJK A;  5EAT A;  3KRO B;  5ILD A;  3N1W F;  5EAU A;  4LLS A;  3VJA A;  2ZCS A;  2AEK A;  2Q9Y A;  4DXJ A;  2E93 A;  2F8C F;  5ILH A;  4H5E F;  4RNQ A;  2F8Z F;  5AYP A;  1DI1 A;  4KQS A;  3TFN A;  1HM7 A;  2PS5 A;  3LGZ B;  5DGN F;  5IKA A;  4MC0 A;  3ACY A;  5HN7 A;  4KVD A;  1V4I A;  3EZ3 A;  2Z52 A;  4FJQ A;  1UBW A;  3N6K F;  1YYQ A;  3EGT A;  5AEL A;  3SDV A;  2Z4Y A;  2O1O A;  2E4O A;  4F6V A;  3ID0 A;  4LPH F;  3WSB A;  5JA0 F;  5JV2 F;  3WEG A;  5B03 A;  3ICN A;  3TFV A;  2ZCQ A;  3RBM A;  1YYS A;  2Z4V A;  3V1V A;  4L2X F;  4QXS F;  2Q58 A;  5DJV F;  2F89 F;  3N1V F;  1N1B A;  3IPI A;  3VJ9 A;  3OAB A;  4XQT F;  3AQC B;  3PDE A;  4LZ0 A;  4LXW A;  5I1U A;  5ERN A;  4PVY F;  3LVS A;  3MAV A;  5DJR F;  2AZJ A;  4DHD A;  3SDU A;  1UBX A;  5CG6 A;  3KRC A;  4OKM A;  3EFQ A;  3ICZ A;  4KVW A;  3WCC A;  3WCF A;  3VJE A;  1HXC A;  2E94 A;  4OGU A;  4LZC A;  5ERM A;  4EA2 A;  3G4F A;  1WL1 A;  4KVI A;  3WEK A;  4EA0 A;  5DGM F;  2Z7I A;  5IMP A;  4NUA A;  3M02 A;  3OAB B;  4K10 A;  2J1P A;  1RTR A;  4LIX A;  3ZL6 A;  4LTV A;  2PS4 A;  5DHI A;  1N23 A;  4LFV F;  2FOR A;  4DZW A;  4RXD A;  4JZX A;  4H5D F;  4NKF A;  3LK5 A;  3M00 A;  3KRC B;  3NPK A;  3ACW A;  3N45 F;  4GAX A;  5JV1 F;  3LDW A;  3WEJ A;  2OPM A;  2E91 A;  3MZV A;  1HXA A;  4KQ5 A;  1DGP A;  2OPN A;  2E95 A;  4OMH A;  2ZCR A;  4KUX A;  5IMI A;  1UBV A;  4RXC A;  3WEF A;  5HN8 A;  2E8X A;  4P0X A;  5DZ2 A;  4P0W A;  5JUZ F;  4N9U A;  1VG3 A;  3KB9 A;  5E8L A;  4UMJ A;  4JVJ F;  2P1C A;  5IM1 A;  3S9V A;  4JXY A;  3PH7 A;  4LOB A;  4LUU A;  4KFA A;  4EA1 A;  5DHK A;  4FP4 A;  1UBY A;  3N5H F;  4Q23 A;  3M0G A;  1WL0 A;  2J1O A;  3Q1O A;  3WCM A;  3WCL A;  4LFE A;  3AQ0 A;  3SAE A;  2Z4W A;  2F94 F;  4GP2 A;  5H9D A;  4E1E A;  4E9U A;  5ILZ A; 
#chains in the Genus database with same CATH topology
 2PS6 A;  1YYU A;  4JYX A;  4KKM A;  3AQB B;  3LMD A;  1VG7 A;  2F92 F;  3WCI A;  3RMG A;  4ZQ8 A;  1RQJ A;  5HNA A;  3KRP A;  5B0I A;  1N1Z A;  5IK6 A;  2Q9Z A;  2J5C A;  2OGD A;  4KQU A;  4KPJ A;  4OMG A;  5A0I A;  3CC9 A;  5B00 A;  3OAC A;  4F62 A;  1PS1 A;  1YHL A;  5A0J A;  1EZF A;  4LLT A;  1WKZ A;  3WEH A;  3VJB A;  2Z4Z A;  4RXA A;  1WY0 A;  3ADZ A;  3WCA A;  3Q2Q A;  1N20 A;  4QPF A;  4NFJ F;  1V4E A;  3ZMC A;  1HX9 A;  5B0J A;  2Z50 A;  3WCJ A;  3V66 A;  2FTZ A;  3LZ9 A;  3LEE A;  3KRP B;  3TS7 A;  5B0M A;  3WCB A;  4RYP A;  4LA5 A;  1VG6 A;  2QIS A;  2E90 A;  3NPR A;  4LPG F;  5ER8 A;  3SDT A;  5IL8 A;  5ILK A;  3LG5 A;  3N3L F;  3WEI A;  3LOM A;  4OKZ A;  3OAC B;  3S4J A;  5A0K A;  2EWG A;  3SDQ A;  2ONH A;  1V4J A;  1JFA A;  3QKC A;  5ILI A;  3W7F A;  4KK2 A;  1N24 A;  3QQV A;  3LJI A;  5DIQ F;  3RYE A;  5B02 A;  3LGK A;  3SDR A;  3G4D A;  4JXN A;  4XQS F;  1V4H A;  3N3D A;  3N5J F;  1YHM A;  3WCG A;  5DGS F;  3UCA A;  3WSA A;  3WCD A;  4H5C F;  3PYB A;  3VJ8 A;  2F9K F;  1RQI A;  3LLW A;  3TC1 A;  2RAH A;  4HD1 A;  1WL3 A;  3NF2 A;  3ZMB A;  4KWD A;  2ONG A;  4E9Z A;  3WCH A;  5DJP F;  3TFP A;  5IK0 A;  4WK5 A;  1YYR A;  1YHK A;  3AE0 A;  5ERO A;  5DW7 A;  5IVG A;  3APZ A;  3ASX A;  3ICK A;  1FPS A;  1YJ4 A;  3KRF A;  3NRI A;  3P8L A;  2DH4 A;  2PS8 A;  3B7L A;  5C05 A;  4KPD A;  2H8O A;  4NG6 A;  2Z78 A;  4MC3 A;  3P5R A;  3LSN A;  4GA3 A;  2E8W A;  5E8K A;  1YQ7 A;  2ZCO A;  4P0V A;  3P41 A;  2ZEV A;  3VJD A;  4GP1 A;  3P5P A;  2Z4X A;  4XQR F;  1ZW5 A;  1VG2 A;  3N0F A;  3PKO A;  3WC9 A;  3Q2Z A;  1HXG A;  3V1X A;  4NFI F;  1YYT A;  3KBK A;  5AFX A;  4LA6 A;  1WL2 A;  2Z7H A;  3DYF A;  1WMW A;  5AHU B;  5HN9 A;  3WJO A;  5EAS A;  5B01 A;  3KRF B;  3DYG A;  3BNX A;  3KRA A;  4F6X A;  2I19 A;  4KVY A;  3N49 F;  2E8T A;  5E8H A;  2AZK A;  2E92 A;  5IMN A;  4JZB A;  5IN8 A;  4DWB A;  5KSX F;  4LZ3 A;  3ACX A;  2PS7 A;  5JV0 F;  3Q30 A;  4DWG A;  3CKE A;  1N22 A;  5IL3 A;  2AEL A;  2ZY1 A;  4N1Z F;  4NKE A;  2VF6 A;  4NFK F;  2ZEU A;  5ILY A;  3N46 F;  3WJN A;  4LFG A;  3OYR A;  4PVX F;  3ZCD A;  3PYA A;  2F7M F;  5B0L A;  1KIZ A;  4DI5 A;  4DEM F;  4RXE A;  2AZL A;  2OA6 A;  1YV5 A;  3IBA A;  1JFG A;  5CG5 A;  3M01 A;  3KRA B;  4MC8 A;  5IK9 A;  1KIY A;  3P8R A;  3M9U A;  2AET A;  2Q80 A;  3KRO A;  3N0G A;  5IKH A;  1HM4 A;  4LTZ A;  3WE9 A;  3ICM A;  1VG4 A;  5B0K A;  3VJC A;  3RYW A;  3DYH A;  5ILJ A;  2E8V A;  3CP6 A;  2E8U A;  1V4K A;  3ZOU A;  3WCE A;  1N21 A;  3BNY A;  3WJK A;  5EAT A;  3KRO B;  5ILD A;  3N1W F;  5EAU A;  4LLS A;  3VJA A;  2ZCS A;  2AEK A;  2Q9Y A;  4DXJ A;  2E93 A;  2F8C F;  5ILH A;  4H5E F;  4RNQ A;  2F8Z F;  5AYP A;  1DI1 A;  4KQS A;  3TFN A;  1HM7 A;  2PS5 A;  3LGZ B;  5DGN F;  5IKA A;  4MC0 A;  3ACY A;  5HN7 A;  4KVD A;  1V4I A;  3EZ3 A;  2Z52 A;  4FJQ A;  1UBW A;  3N6K F;  1YYQ A;  3EGT A;  5AEL A;  3SDV A;  2Z4Y A;  2O1O A;  2E4O A;  4F6V A;  3ID0 A;  4LPH F;  3WSB A;  5JA0 F;  5JV2 F;  3WEG A;  5B03 A;  3ICN A;  3TFV A;  2ZCQ A;  3RBM A;  1YYS A;  2Z4V A;  3V1V A;  4L2X F;  4QXS F;  2Q58 A;  5DJV F;  2F89 F;  3N1V F;  1N1B A;  3IPI A;  3VJ9 A;  3OAB A;  4XQT F;  3AQC B;  3PDE A;  4LZ0 A;  4LXW A;  5I1U A;  5ERN A;  4PVY F;  3LVS A;  3MAV A;  5DJR F;  2AZJ A;  4DHD A;  3SDU A;  1UBX A;  5CG6 A;  3KRC A;  4OKM A;  3EFQ A;  3ICZ A;  4KVW A;  3WCC A;  3WCF A;  3VJE A;  1HXC A;  2E94 A;  4OGU A;  4LZC A;  5ERM A;  4EA2 A;  3G4F A;  1WL1 A;  4KVI A;  3WEK A;  4EA0 A;  5DGM F;  2Z7I A;  5IMP A;  4NUA A;  3M02 A;  3OAB B;  4K10 A;  2J1P A;  1RTR A;  4LIX A;  3ZL6 A;  4LTV A;  2PS4 A;  5DHI A;  1N23 A;  4LFV F;  2FOR A;  4DZW A;  4RXD A;  4JZX A;  4H5D F;  4NKF A;  3LK5 A;  3M00 A;  3KRC B;  3NPK A;  3ACW A;  3N45 F;  4GAX A;  5JV1 F;  3LDW A;  3WEJ A;  2OPM A;  2E91 A;  3MZV A;  1HXA A;  4KQ5 A;  1DGP A;  2OPN A;  2E95 A;  4OMH A;  2ZCR A;  4KUX A;  5IMI A;  1UBV A;  4RXC A;  3WEF A;  5HN8 A;  2E8X A;  4P0X A;  5DZ2 A;  4P0W A;  5JUZ F;  4N9U A;  1VG3 A;  3KB9 A;  5E8L A;  4UMJ A;  4JVJ F;  2P1C A;  5IM1 A;  3S9V A;  4JXY A;  3PH7 A;  4LOB A;  4LUU A;  4KFA A;  4EA1 A;  5DHK A;  4FP4 A;  1UBY A;  3N5H F;  4Q23 A;  3M0G A;  1WL0 A;  2J1O A;  3Q1O A;  3WCM A;  3WCL A;  4LFE A;  3AQ0 A;  3SAE A;  2Z4W A;  2F94 F;  4GP2 A;  5H9D A;  4E1E A;  4E9U A;  5ILZ A; 
#chains in the Genus database with same CATH homology
 2PS6 A;  1YYU A;  4JYX A;  4KKM A;  3AQB B;  3LMD A;  1VG7 A;  2F92 F;  3WCI A;  3RMG A;  4ZQ8 A;  1RQJ A;  5HNA A;  3KRP A;  5B0I A;  1N1Z A;  5IK6 A;  2Q9Z A;  2J5C A;  2OGD A;  4KQU A;  4KPJ A;  4OMG A;  5A0I A;  3CC9 A;  5B00 A;  3OAC A;  4F62 A;  1PS1 A;  1YHL A;  5A0J A;  1EZF A;  4LLT A;  1WKZ A;  3WEH A;  3VJB A;  2Z4Z A;  4RXA A;  1WY0 A;  3ADZ A;  3WCA A;  3Q2Q A;  1N20 A;  4QPF A;  4NFJ F;  1V4E A;  3ZMC A;  1HX9 A;  5B0J A;  2Z50 A;  3WCJ A;  3V66 A;  2FTZ A;  3LZ9 A;  3LEE A;  3KRP B;  3TS7 A;  5B0M A;  3WCB A;  4RYP A;  4LA5 A;  1VG6 A;  2QIS A;  2E90 A;  3NPR A;  4LPG F;  5ER8 A;  3SDT A;  5IL8 A;  5ILK A;  3LG5 A;  3N3L F;  3WEI A;  3LOM A;  4OKZ A;  3OAC B;  3S4J A;  5A0K A;  2EWG A;  3SDQ A;  2ONH A;  1V4J A;  1JFA A;  3QKC A;  5ILI A;  3W7F A;  4KK2 A;  1N24 A;  3QQV A;  3LJI A;  5DIQ F;  3RYE A;  5B02 A;  3LGK A;  3SDR A;  3G4D A;  4JXN A;  4XQS F;  1V4H A;  3N3D A;  3N5J F;  1YHM A;  3WCG A;  5DGS F;  3UCA A;  3WSA A;  3WCD A;  4H5C F;  3PYB A;  3VJ8 A;  2F9K F;  1RQI A;  3LLW A;  3TC1 A;  2RAH A;  4HD1 A;  1WL3 A;  3NF2 A;  3ZMB A;  4KWD A;  2ONG A;  4E9Z A;  3WCH A;  5DJP F;  3TFP A;  5IK0 A;  4WK5 A;  1YYR A;  1YHK A;  3AE0 A;  5ERO A;  5DW7 A;  5IVG A;  3APZ A;  3ASX A;  3ICK A;  1FPS A;  1YJ4 A;  3KRF A;  3NRI A;  3P8L A;  2DH4 A;  2PS8 A;  3B7L A;  5C05 A;  4KPD A;  2H8O A;  4NG6 A;  2Z78 A;  4MC3 A;  3P5R A;  3LSN A;  4GA3 A;  2E8W A;  5E8K A;  1YQ7 A;  2ZCO A;  4P0V A;  3P41 A;  2ZEV A;  3VJD A;  4GP1 A;  3P5P A;  2Z4X A;  4XQR F;  1ZW5 A;  1VG2 A;  3N0F A;  3PKO A;  3WC9 A;  3Q2Z A;  1HXG A;  3V1X A;  4NFI F;  1YYT A;  3KBK A;  5AFX A;  4LA6 A;  1WL2 A;  2Z7H A;  3DYF A;  1WMW A;  5AHU B;  5HN9 A;  3WJO A;  5EAS A;  5B01 A;  3KRF B;  3DYG A;  3BNX A;  3KRA A;  4F6X A;  2I19 A;  4KVY A;  3N49 F;  2E8T A;  5E8H A;  2AZK A;  2E92 A;  5IMN A;  4JZB A;  5IN8 A;  4DWB A;  5KSX F;  4LZ3 A;  3ACX A;  2PS7 A;  5JV0 F;  3Q30 A;  4DWG A;  3CKE A;  1N22 A;  5IL3 A;  2AEL A;  2ZY1 A;  4N1Z F;  4NKE A;  2VF6 A;  4NFK F;  2ZEU A;  5ILY A;  3N46 F;  3WJN A;  4LFG A;  3OYR A;  4PVX F;  3ZCD A;  3PYA A;  2F7M F;  5B0L A;  1KIZ A;  4DI5 A;  4DEM F;  4RXE A;  2AZL A;  2OA6 A;  1YV5 A;  3IBA A;  1JFG A;  5CG5 A;  3M01 A;  3KRA B;  4MC8 A;  5IK9 A;  1KIY A;  3P8R A;  3M9U A;  2AET A;  2Q80 A;  3KRO A;  3N0G A;  5IKH A;  1HM4 A;  4LTZ A;  3WE9 A;  3ICM A;  1VG4 A;  5B0K A;  3VJC A;  3RYW A;  3DYH A;  5ILJ A;  2E8V A;  3CP6 A;  2E8U A;  1V4K A;  3ZOU A;  3WCE A;  1N21 A;  3BNY A;  3WJK A;  5EAT A;  3KRO B;  5ILD A;  3N1W F;  5EAU A;  4LLS A;  3VJA A;  2ZCS A;  2AEK A;  2Q9Y A;  4DXJ A;  2E93 A;  2F8C F;  5ILH A;  4H5E F;  4RNQ A;  2F8Z F;  5AYP A;  1DI1 A;  4KQS A;  3TFN A;  1HM7 A;  2PS5 A;  3LGZ B;  5DGN F;  5IKA A;  4MC0 A;  3ACY A;  5HN7 A;  4KVD A;  1V4I A;  3EZ3 A;  2Z52 A;  4FJQ A;  1UBW A;  3N6K F;  1YYQ A;  3EGT A;  5AEL A;  3SDV A;  2Z4Y A;  2O1O A;  2E4O A;  4F6V A;  3ID0 A;  4LPH F;  3WSB A;  5JA0 F;  5JV2 F;  3WEG A;  5B03 A;  3ICN A;  3TFV A;  2ZCQ A;  3RBM A;  1YYS A;  2Z4V A;  3V1V A;  4L2X F;  4QXS F;  2Q58 A;  5DJV F;  2F89 F;  3N1V F;  1N1B A;  3IPI A;  3VJ9 A;  3OAB A;  4XQT F;  3AQC B;  3PDE A;  4LZ0 A;  4LXW A;  5I1U A;  5ERN A;  4PVY F;  3LVS A;  3MAV A;  5DJR F;  2AZJ A;  4DHD A;  3SDU A;  1UBX A;  5CG6 A;  3KRC A;  4OKM A;  3EFQ A;  3ICZ A;  4KVW A;  3WCC A;  3WCF A;  3VJE A;  1HXC A;  2E94 A;  4OGU A;  4LZC A;  5ERM A;  4EA2 A;  3G4F A;  1WL1 A;  4KVI A;  3WEK A;  4EA0 A;  5DGM F;  2Z7I A;  5IMP A;  4NUA A;  3M02 A;  3OAB B;  4K10 A;  2J1P A;  1RTR A;  4LIX A;  3ZL6 A;  4LTV A;  2PS4 A;  5DHI A;  1N23 A;  4LFV F;  2FOR A;  4DZW A;  4RXD A;  4JZX A;  4H5D F;  4NKF A;  3LK5 A;  3M00 A;  3KRC B;  3NPK A;  3ACW A;  3N45 F;  4GAX A;  5JV1 F;  3LDW A;  3WEJ A;  2OPM A;  2E91 A;  3MZV A;  1HXA A;  4KQ5 A;  1DGP A;  2OPN A;  2E95 A;  4OMH A;  2ZCR A;  4KUX A;  5IMI A;  1UBV A;  4RXC A;  3WEF A;  5HN8 A;  2E8X A;  4P0X A;  5DZ2 A;  4P0W A;  5JUZ F;  4N9U A;  1VG3 A;  3KB9 A;  5E8L A;  4UMJ A;  4JVJ F;  2P1C A;  5IM1 A;  3S9V A;  4JXY A;  3PH7 A;  4LOB A;  4LUU A;  4KFA A;  4EA1 A;  5DHK A;  4FP4 A;  1UBY A;  3N5H F;  4Q23 A;  3M0G A;  1WL0 A;  2J1O A;  3Q1O A;  3WCM A;  3WCL A;  4LFE A;  3AQ0 A;  3SAE A;  2Z4W A;  2F94 F;  4GP2 A;  5H9D A;  4E1E A;  4E9U A;  5ILZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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