4JVJF

Crystal structure of human fpps in complex with magnesium, cl01131, and sulfate
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
pubmed doi rcsb
source organism Homo sapiens
total genus 130
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2013-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4jvjF00
5IKHA 3Q2ZA 4KK2A 2ZCSA 4LA5A 3V66A 5IMIA 4KWDA 5JUZF 5B0LA 1WL1A 3SDRA 3ACYA 3WCJA 3LSNA 3CC9A 4MC8A 3ID0A 4LZ3A 2AETA 3S4JA 5IKAA 1WMWA 5KSXF 5ERNA 4KVWA 2AELA 3P5PA 4RXAA 4LIXA 4OMGA 4E1EA 3M0GA 3N6KF 3KRPA 3IPIA 4KUXA 3M9UA 4EA0A 3WEJA 3KROB 1N22A 2O1OA 3WCIA 3NRIA 4KFAA 2F8CF 3B7LA 1RQIA 4GAXA 1HXCA 3QQVA 5ERMA 1HM4A 3P5RA 5HN7A 1YHLA 5B00A 4EA2A 4OMHA 1UBVA 4N9UA 4GP1A 4H5DF 5IMNA 1YYRA 3ZL6A 3V1VA 4HD1A 3M01A 3LMDA 5IM1A 3DYFA 2Q80A 4H5CF 3ZMBA 2F94F 1VG7A 3ACXA 5DZ2A 3W7FA 3TFPA 5B0JA 3KRCA 3SDUA 3N0GA 4DI5A 4E9UA 3N49F 3AQBB 3KRAB 4NFJF 4KQSA 2PS5A 3WEGA 1RQJA 2Z4VA 4XQSF 5IMPA 5E8HA 3VJAA 3WEFA 2F7MF 2ONGA 2E8TA 5E8LA 2DH4A 3WJOA 1ZW5A 4NKEA 1YYUA 3LLWA 5H9DA 5B02A 3ICKA 4KVDA 5DGNF 3LVSA 4PVYF 2E94A 5B0MA 3OACA 2Z78A 3APZA 5EATA 4FP4A 3TFNA 4P0VA 2I19A 3CKEA 4LZ0A 3VJ8A 1EZFA 3KROA 5IL8A 2E90A 3G4DA 1VG4A 2PS6A 3ADZA 3OYRA 3RYEA 4JZBA 2E8WA 1YYTA 3VJDA 4XQTF 2ZCRA 1N21A 3N0FA 1RTRA 1KIZA 3AE0A 5DHKA 3N1VF 4LZCA 1HXGA 2E4OA 2Q9YA 3WCAA 1N1BA 2OPNA 4LUUA 4WK5A 3WC9A 1HXAA 1WL3A 1UBWA 5HN9A 3WCCA 4RXDA 2Z7HA 4KPJA 1KIYA 4LA6A 4P0XA 2J5CA 4LTVA 1N24A 3WSAA 1VG2A 3P41A 3LZ9A 5DIQF 3VJBA 3ZMCA 2OA6A 5IN8A 3SDTA 3LDWA 2Z4XA 1HM7A 3NF2A 5CG6A 5IK0A 3ICMA 1HX9A 4F62A 1VG3A 3WCFA 5HN8A 2Q58A 3TS7A 3ICNA 3Q30A 1VG6A 3QKCA 4JXYA 2FTZA 4MC3A 2E93A 5CG5A 5IL3A 3LK5A 5A0IA 1N23A 3TFVA 3M02A 3MZVA 4OGUA 3N1WF 4OKMA 3DYGA 4KVYA 5AELA 2Z4ZA 1YV5A 3VJ9A 5B03A 2AZKA 5JV2F 1UBYA 4RNQA 3WCBA 4RYPA 3VJCA 3SAEA 5AHUB 4P0WA 3KBKA 3KRFB 2AZJA 3WJKA 5DW7A 2Z50A 3WCLA 5DHIA 1YHKA 2J1PA 4GP2A 3KB9A 2AZLA 2PS8A 4OKZA 3EZ3A 5DJRF 3CP6A 3ZOUA 2E91A 3LEEA 2Z4YA 3WEHA 4PVXF 3OABB 4DHDA 4KPDA 5IVGA 5B0KA 2E8VA 2ZEUA 2PS7A 2E92A 2OPMA 3PKOA 4KKMA 2Z4WA 4E9ZA 4LXWA 4QXSF 5DGSF 3EGTA 3ICZA 4XQRF 4RXCA 4KQUA 1JFGA 4NKFA 4QPFA 4EA1A 4ZQ8A 3RBMA 4LPGF 3S9VA 1YHMA 2F9KF 2E95A 2ZCOA 3PH7A 3ACWA 3PYBA 4LPHF 3WCGA 5ILDA 3N45F 4DWGA 5JV0F 4LFGA 2ONHA 3P8RA 3VJEA 5ILYA 4L2XF 5AYPA 5ILJA 3TC1A 3KRAA 3M00A 1DGPA 5ILZA 1JFAA 3Q2QA 3AQ0A 5EASA 3N3DA 2ZY1A 3WE9A 1FPSA 3SDQA 2F89F 1DI1A 2RAHA 5I1UA 5E8KA 3AQCB 3ZCDA 2E8XA 3NPRA 3KRFA 4KVIA 1YYSA 5ILKA 5A0JA 4K10A 4LLSA 1WL2A 3Q1OA 5B0IA 5B01A 3OACB 4LFEA 3PDEA 3LOMA 4NG6A 3DYHA 1V4HA 4FJQA 3OABA 3LGZB 4DZWA 5JV1F 4LOBA 4UMJA 3N5JF 4JZXA 2OGDA 1V4IA 1WKZA 5A0KA 3NPKA 1WY0A 3UCAA 1UBXA 4DXJA 2VF6A 5AFXA 5ILHA 4RXEA 2Z7IA 4H5EF 1WL0A 3V1XA 3WCEA 3LJIA 1N20A 5EROA 2P1CA 3LGKA 3WEKA 3WSBA 5DJVF 4LFVF 3BNYA 1YYQA 3N5HF 3WCDA 3G4FA 4NFIF 4MC0A 3ASXA 3WCMA 5ER8A 3IBAA 3N46F 4GA3A 2EWGA 4LLTA 4JYXA 4JXNA 5ILIA 3KRPB 3PYAA 4Q23A 2Z52A 2H8OA 5EAUA 5DJPF 5JA0F 2PS4A 4DEMF 4LTZA 2ZEVA 2J1OA 3WCHA 4F6XA 2F8ZF 5DGMF 4KQ5A 2E8UA 3WJNA 4NUAA 2Q9ZA 2F92F 5C05A 3SDVA 4DWBA 4JVJF 1N1ZA 1V4EA 4NFKF 2AEKA 5IK6A 1YJ4A 3WEIA 2FORA 2QISA 1V4KA 4N1ZF 1V4JA 3BNXA 3N3LF 4F6VA 3KRCB 3LG5A 3RMGA 3MAVA 2ZCQA 5IK9A 3EFQA 5HNAA 1YQ7A 3P8LA 3RYWA 1PS1A
chains in the Genus database with same CATH superfamily
5IKHA 3Q2ZA 4KK2A 2ZCSA 4LA5A 3V66A 5IMIA 4KWDA 5JUZF 5B0LA 1WL1A 3SDRA 3ACYA 3WCJA 3LSNA 3CC9A 4MC8A 3ID0A 4LZ3A 2AETA 3S4JA 5IKAA 1WMWA 5KSXF 5ERNA 4KVWA 2AELA 3P5PA 4RXAA 4LIXA 4OMGA 4E1EA 3M0GA 3N6KF 3KRPA 3IPIA 4KUXA 3M9UA 4EA0A 3WEJA 3KROB 1N22A 2O1OA 3WCIA 3NRIA 4KFAA 2F8CF 3B7LA 1RQIA 4GAXA 1HXCA 3QQVA 5ERMA 1HM4A 3P5RA 5HN7A 1YHLA 5B00A 4EA2A 4OMHA 1UBVA 4N9UA 4GP1A 4H5DF 5IMNA 1YYRA 3ZL6A 3V1VA 4HD1A 3M01A 3LMDA 5IM1A 3DYFA 2Q80A 4H5CF 3ZMBA 2F94F 1VG7A 3ACXA 5DZ2A 3W7FA 3TFPA 5B0JA 3KRCA 3SDUA 3N0GA 4DI5A 4E9UA 3N49F 3AQBB 3KRAB 4NFJF 4KQSA 2PS5A 3WEGA 1RQJA 2Z4VA 4XQSF 5IMPA 5E8HA 3VJAA 3WEFA 2F7MF 2ONGA 2E8TA 5E8LA 2DH4A 3WJOA 1ZW5A 4NKEA 1YYUA 3LLWA 5H9DA 5B02A 3ICKA 4KVDA 5DGNF 3LVSA 4PVYF 2E94A 5B0MA 3OACA 2Z78A 3APZA 5EATA 4FP4A 3TFNA 4P0VA 2I19A 3CKEA 4LZ0A 3VJ8A 1EZFA 3KROA 5IL8A 2E90A 3G4DA 1VG4A 2PS6A 3ADZA 3OYRA 3RYEA 4JZBA 2E8WA 1YYTA 3VJDA 4XQTF 2ZCRA 1N21A 3N0FA 1RTRA 1KIZA 3AE0A 5DHKA 3N1VF 4LZCA 1HXGA 2E4OA 2Q9YA 3WCAA 1N1BA 2OPNA 4LUUA 4WK5A 3WC9A 1HXAA 1WL3A 1UBWA 5HN9A 3WCCA 4RXDA 2Z7HA 4KPJA 1KIYA 4LA6A 4P0XA 2J5CA 4LTVA 1N24A 3WSAA 1VG2A 3P41A 3LZ9A 5DIQF 3VJBA 3ZMCA 2OA6A 5IN8A 3SDTA 3LDWA 2Z4XA 1HM7A 3NF2A 5CG6A 5IK0A 3ICMA 1HX9A 4F62A 1VG3A 3WCFA 5HN8A 2Q58A 3TS7A 3ICNA 3Q30A 1VG6A 3QKCA 4JXYA 2FTZA 4MC3A 2E93A 5CG5A 5IL3A 3LK5A 5A0IA 1N23A 3TFVA 3M02A 3MZVA 4OGUA 3N1WF 4OKMA 3DYGA 4KVYA 5AELA 2Z4ZA 1YV5A 3VJ9A 5B03A 2AZKA 5JV2F 1UBYA 4RNQA 3WCBA 4RYPA 3VJCA 3SAEA 5AHUB 4P0WA 3KBKA 3KRFB 2AZJA 3WJKA 5DW7A 2Z50A 3WCLA 5DHIA 1YHKA 2J1PA 4GP2A 3KB9A 2AZLA 2PS8A 4OKZA 3EZ3A 5DJRF 3CP6A 3ZOUA 2E91A 3LEEA 2Z4YA 3WEHA 4PVXF 3OABB 4DHDA 4KPDA 5IVGA 5B0KA 2E8VA 2ZEUA 2PS7A 2E92A 2OPMA 3PKOA 4KKMA 2Z4WA 4E9ZA 4LXWA 4QXSF 5DGSF 3EGTA 3ICZA 4XQRF 4RXCA 4KQUA 1JFGA 4NKFA 4QPFA 4EA1A 4ZQ8A 3RBMA 4LPGF 3S9VA 1YHMA 2F9KF 2E95A 2ZCOA 3PH7A 3ACWA 3PYBA 4LPHF 3WCGA 5ILDA 3N45F 4DWGA 5JV0F 4LFGA 2ONHA 3P8RA 3VJEA 5ILYA 4L2XF 5AYPA 5ILJA 3TC1A 3KRAA 3M00A 1DGPA 5ILZA 1JFAA 3Q2QA 3AQ0A 5EASA 3N3DA 2ZY1A 3WE9A 1FPSA 3SDQA 2F89F 1DI1A 2RAHA 5I1UA 5E8KA 3AQCB 3ZCDA 2E8XA 3NPRA 3KRFA 4KVIA 1YYSA 5ILKA 5A0JA 4K10A 4LLSA 1WL2A 3Q1OA 5B0IA 5B01A 3OACB 4LFEA 3PDEA 3LOMA 4NG6A 3DYHA 1V4HA 4FJQA 3OABA 3LGZB 4DZWA 5JV1F 4LOBA 4UMJA 3N5JF 4JZXA 2OGDA 1V4IA 1WKZA 5A0KA 3NPKA 1WY0A 3UCAA 1UBXA 4DXJA 2VF6A 5AFXA 5ILHA 4RXEA 2Z7IA 4H5EF 1WL0A 3V1XA 3WCEA 3LJIA 1N20A 5EROA 2P1CA 3LGKA 3WEKA 3WSBA 5DJVF 4LFVF 3BNYA 1YYQA 3N5HF 3WCDA 3G4FA 4NFIF 4MC0A 3ASXA 3WCMA 5ER8A 3IBAA 3N46F 4GA3A 2EWGA 4LLTA 4JYXA 4JXNA 5ILIA 3KRPB 3PYAA 4Q23A 2Z52A 2H8OA 5EAUA 5DJPF 5JA0F 2PS4A 4DEMF 4LTZA 2ZEVA 2J1OA 3WCHA 4F6XA 2F8ZF 5DGMF 4KQ5A 2E8UA 3WJNA 4NUAA 2Q9ZA 2F92F 5C05A 3SDVA 4DWBA 4JVJF 1N1ZA 1V4EA 4NFKF 2AEKA 5IK6A 1YJ4A 3WEIA 2FORA 2QISA 1V4KA 4N1ZF 1V4JA 3BNXA 3N3LF 4F6VA 3KRCB 3LG5A 3RMGA 3MAVA 2ZCQA 5IK9A 3EFQA 5HNAA 1YQ7A 3P8LA 3RYWA 1PS1A
chains in the Genus database with same CATH topology
5IKHA 3Q2ZA 4KK2A 2ZCSA 4LA5A 3V66A 5IMIA 4KWDA 5JUZF 5B0LA 1WL1A 3SDRA 3ACYA 3WCJA 3LSNA 3CC9A 4MC8A 3ID0A 4LZ3A 2AETA 3S4JA 5IKAA 1WMWA 5KSXF 5ERNA 4KVWA 2AELA 3P5PA 4RXAA 4LIXA 4OMGA 4E1EA 3M0GA 3N6KF 3KRPA 3IPIA 4KUXA 3M9UA 4EA0A 3WEJA 3KROB 1N22A 2O1OA 3WCIA 3NRIA 4KFAA 2F8CF 3B7LA 1RQIA 4GAXA 1HXCA 3QQVA 5ERMA 1HM4A 3P5RA 5HN7A 1YHLA 5B00A 4EA2A 4OMHA 1UBVA 4N9UA 4GP1A 4H5DF 5IMNA 1YYRA 3ZL6A 3V1VA 4HD1A 3M01A 3LMDA 5IM1A 3DYFA 2Q80A 4H5CF 3ZMBA 2F94F 1VG7A 3ACXA 5DZ2A 3W7FA 3TFPA 5B0JA 3KRCA 3SDUA 3N0GA 4DI5A 4E9UA 3N49F 3AQBB 3KRAB 4NFJF 4KQSA 2PS5A 3WEGA 1RQJA 2Z4VA 4XQSF 5IMPA 5E8HA 3VJAA 3WEFA 2F7MF 2ONGA 2E8TA 5E8LA 2DH4A 3WJOA 1ZW5A 4NKEA 1YYUA 3LLWA 5H9DA 5B02A 3ICKA 4KVDA 5DGNF 3LVSA 4PVYF 2E94A 5B0MA 3OACA 2Z78A 3APZA 5EATA 4FP4A 3TFNA 4P0VA 2I19A 3CKEA 4LZ0A 3VJ8A 1EZFA 3KROA 5IL8A 2E90A 3G4DA 1VG4A 2PS6A 3ADZA 3OYRA 3RYEA 4JZBA 2E8WA 1YYTA 3VJDA 4XQTF 2ZCRA 1N21A 3N0FA 1RTRA 1KIZA 3AE0A 5DHKA 3N1VF 4LZCA 1HXGA 2E4OA 2Q9YA 3WCAA 1N1BA 2OPNA 4LUUA 4WK5A 3WC9A 1HXAA 1WL3A 1UBWA 5HN9A 3WCCA 4RXDA 2Z7HA 4KPJA 1KIYA 4LA6A 4P0XA 2J5CA 4LTVA 1N24A 3WSAA 1VG2A 3P41A 3LZ9A 5DIQF 3VJBA 3ZMCA 2OA6A 5IN8A 3SDTA 3LDWA 2Z4XA 1HM7A 3NF2A 5CG6A 5IK0A 3ICMA 1HX9A 4F62A 1VG3A 3WCFA 5HN8A 2Q58A 3TS7A 3ICNA 3Q30A 1VG6A 3QKCA 4JXYA 2FTZA 4MC3A 2E93A 5CG5A 5IL3A 3LK5A 5A0IA 1N23A 3TFVA 3M02A 3MZVA 4OGUA 3N1WF 4OKMA 3DYGA 4KVYA 5AELA 2Z4ZA 1YV5A 3VJ9A 5B03A 2AZKA 5JV2F 1UBYA 4RNQA 3WCBA 4RYPA 3VJCA 3SAEA 5AHUB 4P0WA 3KBKA 3KRFB 2AZJA 3WJKA 5DW7A 2Z50A 3WCLA 5DHIA 1YHKA 2J1PA 4GP2A 3KB9A 2AZLA 2PS8A 4OKZA 3EZ3A 5DJRF 3CP6A 3ZOUA 2E91A 3LEEA 2Z4YA 3WEHA 4PVXF 3OABB 4DHDA 4KPDA 5IVGA 5B0KA 2E8VA 2ZEUA 2PS7A 2E92A 2OPMA 3PKOA 4KKMA 2Z4WA 4E9ZA 4LXWA 4QXSF 5DGSF 3EGTA 3ICZA 4XQRF 4RXCA 4KQUA 1JFGA 4NKFA 4QPFA 4EA1A 4ZQ8A 3RBMA 4LPGF 3S9VA 1YHMA 2F9KF 2E95A 2ZCOA 3PH7A 3ACWA 3PYBA 4LPHF 3WCGA 5ILDA 3N45F 4DWGA 5JV0F 4LFGA 2ONHA 3P8RA 3VJEA 5ILYA 4L2XF 5AYPA 5ILJA 3TC1A 3KRAA 3M00A 1DGPA 5ILZA 1JFAA 3Q2QA 3AQ0A 5EASA 3N3DA 2ZY1A 3WE9A 1FPSA 3SDQA 2F89F 1DI1A 2RAHA 5I1UA 5E8KA 3AQCB 3ZCDA 2E8XA 3NPRA 3KRFA 4KVIA 1YYSA 5ILKA 5A0JA 4K10A 4LLSA 1WL2A 3Q1OA 5B0IA 5B01A 3OACB 4LFEA 3PDEA 3LOMA 4NG6A 3DYHA 1V4HA 4FJQA 3OABA 3LGZB 4DZWA 5JV1F 4LOBA 4UMJA 3N5JF 4JZXA 2OGDA 1V4IA 1WKZA 5A0KA 3NPKA 1WY0A 3UCAA 1UBXA 4DXJA 2VF6A 5AFXA 5ILHA 4RXEA 2Z7IA 4H5EF 1WL0A 3V1XA 3WCEA 3LJIA 1N20A 5EROA 2P1CA 3LGKA 3WEKA 3WSBA 5DJVF 4LFVF 3BNYA 1YYQA 3N5HF 3WCDA 3G4FA 4NFIF 4MC0A 3ASXA 3WCMA 5ER8A 3IBAA 3N46F 4GA3A 2EWGA 4LLTA 4JYXA 4JXNA 5ILIA 3KRPB 3PYAA 4Q23A 2Z52A 2H8OA 5EAUA 5DJPF 5JA0F 2PS4A 4DEMF 4LTZA 2ZEVA 2J1OA 3WCHA 4F6XA 2F8ZF 5DGMF 4KQ5A 2E8UA 3WJNA 4NUAA 2Q9ZA 2F92F 5C05A 3SDVA 4DWBA 4JVJF 1N1ZA 1V4EA 4NFKF 2AEKA 5IK6A 1YJ4A 3WEIA 2FORA 2QISA 1V4KA 4N1ZF 1V4JA 3BNXA 3N3LF 4F6VA 3KRCB 3LG5A 3RMGA 3MAVA 2ZCQA 5IK9A 3EFQA 5HNAA 1YQ7A 3P8LA 3RYWA 1PS1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IKH A;  3Q2Z A;  4KK2 A;  2ZCS A;  4LA5 A;  3V66 A;  5IMI A;  4KWD A;  5JUZ F;  5B0L A;  1WL1 A;  3SDR A;  3ACY A;  3WCJ A;  3LSN A;  3CC9 A;  4MC8 A;  3ID0 A;  4LZ3 A;  2AET A;  3S4J A;  5IKA A;  1WMW A;  5KSX F;  5ERN A;  4KVW A;  2AEL A;  3P5P A;  4RXA A;  4LIX A;  4OMG A;  4E1E A;  3M0G A;  3N6K F;  3KRP A;  3IPI A;  4KUX A;  3M9U A;  4EA0 A;  3WEJ A;  3KRO B;  1N22 A;  2O1O A;  3WCI A;  3NRI A;  4KFA A;  2F8C F;  3B7L A;  1RQI A;  4GAX A;  1HXC A;  3QQV A;  5ERM A;  1HM4 A;  3P5R A;  5HN7 A;  1YHL A;  5B00 A;  4EA2 A;  4OMH A;  1UBV A;  4N9U A;  4GP1 A;  4H5D F;  5IMN A;  1YYR A;  3ZL6 A;  3V1V A;  4HD1 A;  3M01 A;  3LMD A;  5IM1 A;  3DYF A;  2Q80 A;  4H5C F;  3ZMB A;  2F94 F;  1VG7 A;  3ACX A;  5DZ2 A;  3W7F A;  3TFP A;  5B0J A;  3KRC A;  3SDU A;  3N0G A;  4DI5 A;  4E9U A;  3N49 F;  3AQB B;  3KRA B;  4NFJ F;  4KQS A;  2PS5 A;  3WEG A;  1RQJ A;  2Z4V A;  4XQS F;  5IMP A;  5E8H A;  3VJA A;  3WEF A;  2F7M F;  2ONG A;  2E8T A;  5E8L A;  2DH4 A;  3WJO A;  1ZW5 A;  4NKE A;  1YYU A;  3LLW A;  5H9D A;  5B02 A;  3ICK A;  4KVD A;  5DGN F;  3LVS A;  4PVY F;  2E94 A;  5B0M A;  3OAC A;  2Z78 A;  3APZ A;  5EAT A;  4FP4 A;  3TFN A;  4P0V A;  2I19 A;  3CKE A;  4LZ0 A;  3VJ8 A;  1EZF A;  3KRO A;  5IL8 A;  2E90 A;  3G4D A;  1VG4 A;  2PS6 A;  3ADZ A;  3OYR A;  3RYE A;  4JZB A;  2E8W A;  1YYT A;  3VJD A;  4XQT F;  2ZCR A;  1N21 A;  3N0F A;  1RTR A;  1KIZ A;  3AE0 A;  5DHK A;  3N1V F;  4LZC A;  1HXG A;  2E4O A;  2Q9Y A;  3WCA A;  1N1B A;  2OPN A;  4LUU A;  4WK5 A;  3WC9 A;  1HXA A;  1WL3 A;  1UBW A;  5HN9 A;  3WCC A;  4RXD A;  2Z7H A;  4KPJ A;  1KIY A;  4LA6 A;  4P0X A;  2J5C A;  4LTV A;  1N24 A;  3WSA A;  1VG2 A;  3P41 A;  3LZ9 A;  5DIQ F;  3VJB A;  3ZMC A;  2OA6 A;  5IN8 A;  3SDT A;  3LDW A;  2Z4X A;  1HM7 A;  3NF2 A;  5CG6 A;  5IK0 A;  3ICM A;  1HX9 A;  4F62 A;  1VG3 A;  3WCF A;  5HN8 A;  2Q58 A;  3TS7 A;  3ICN A;  3Q30 A;  1VG6 A;  3QKC A;  4JXY A;  2FTZ A;  4MC3 A;  2E93 A;  5CG5 A;  5IL3 A;  3LK5 A;  5A0I A;  1N23 A;  3TFV A;  3M02 A;  3MZV A;  4OGU A;  3N1W F;  4OKM A;  3DYG A;  4KVY A;  5AEL A;  2Z4Z A;  1YV5 A;  3VJ9 A;  5B03 A;  2AZK A;  5JV2 F;  1UBY A;  4RNQ A;  3WCB A;  4RYP A;  3VJC A;  3SAE A;  5AHU B;  4P0W A;  3KBK A;  3KRF B;  2AZJ A;  3WJK A;  5DW7 A;  2Z50 A;  3WCL A;  5DHI A;  1YHK A;  2J1P A;  4GP2 A;  3KB9 A;  2AZL A;  2PS8 A;  4OKZ A;  3EZ3 A;  5DJR F;  3CP6 A;  3ZOU A;  2E91 A;  3LEE A;  2Z4Y A;  3WEH A;  4PVX F;  3OAB B;  4DHD A;  4KPD A;  5IVG A;  5B0K A;  2E8V A;  2ZEU A;  2PS7 A;  2E92 A;  2OPM A;  3PKO A;  4KKM A;  2Z4W A;  4E9Z A;  4LXW A;  4QXS F;  5DGS F;  3EGT A;  3ICZ A;  4XQR F;  4RXC A;  4KQU A;  1JFG A;  4NKF A;  4QPF A;  4EA1 A;  4ZQ8 A;  3RBM A;  4LPG F;  3S9V A;  1YHM A;  2F9K F;  2E95 A;  2ZCO A;  3PH7 A;  3ACW A;  3PYB A;  4LPH F;  3WCG A;  5ILD A;  3N45 F;  4DWG A;  5JV0 F;  4LFG A;  2ONH A;  3P8R A;  3VJE A;  5ILY A;  4L2X F;  5AYP A;  5ILJ A;  3TC1 A;  3KRA A;  3M00 A;  1DGP A;  5ILZ A;  1JFA A;  3Q2Q A;  3AQ0 A;  5EAS A;  3N3D A;  2ZY1 A;  3WE9 A;  1FPS A;  3SDQ A;  2F89 F;  1DI1 A;  2RAH A;  5I1U A;  5E8K A;  3AQC B;  3ZCD A;  2E8X A;  3NPR A;  3KRF A;  4KVI A;  1YYS A;  5ILK A;  5A0J A;  4K10 A;  4LLS A;  1WL2 A;  3Q1O A;  5B0I A;  5B01 A;  3OAC B;  4LFE A;  3PDE A;  3LOM A;  4NG6 A;  3DYH A;  1V4H A;  4FJQ A;  3OAB A;  3LGZ B;  4DZW A;  5JV1 F;  4LOB A;  4UMJ A;  3N5J F;  4JZX A;  2OGD A;  1V4I A;  1WKZ A;  5A0K A;  3NPK A;  1WY0 A;  3UCA A;  1UBX A;  4DXJ A;  2VF6 A;  5AFX A;  5ILH A;  4RXE A;  2Z7I A;  4H5E F;  1WL0 A;  3V1X A;  3WCE A;  3LJI A;  1N20 A;  5ERO A;  2P1C A;  3LGK A;  3WEK A;  3WSB A;  5DJV F;  4LFV F;  3BNY A;  1YYQ A;  3N5H F;  3WCD A;  3G4F A;  4NFI F;  4MC0 A;  3ASX A;  3WCM A;  5ER8 A;  3IBA A;  3N46 F;  4GA3 A;  2EWG A;  4LLT A;  4JYX A;  4JXN A;  5ILI A;  3KRP B;  3PYA A;  4Q23 A;  2Z52 A;  2H8O A;  5EAU A;  5DJP F;  5JA0 F;  2PS4 A;  4DEM F;  4LTZ A;  2ZEV A;  2J1O A;  3WCH A;  4F6X A;  2F8Z F;  5DGM F;  4KQ5 A;  2E8U A;  3WJN A;  4NUA A;  2Q9Z A;  2F92 F;  5C05 A;  3SDV A;  4DWB A;  4JVJ F;  1N1Z A;  1V4E A;  4NFK F;  2AEK A;  5IK6 A;  1YJ4 A;  3WEI A;  2FOR A;  2QIS A;  1V4K A;  4N1Z F;  1V4J A;  3BNX A;  3N3L F;  4F6V A;  3KRC B;  3LG5 A;  3RMG A;  3MAV A;  2ZCQ A;  5IK9 A;  3EFQ A;  5HNA A;  1YQ7 A;  3P8L A;  3RYW A;  1PS1 A; 
#chains in the Genus database with same CATH topology
 5IKH A;  3Q2Z A;  4KK2 A;  2ZCS A;  4LA5 A;  3V66 A;  5IMI A;  4KWD A;  5JUZ F;  5B0L A;  1WL1 A;  3SDR A;  3ACY A;  3WCJ A;  3LSN A;  3CC9 A;  4MC8 A;  3ID0 A;  4LZ3 A;  2AET A;  3S4J A;  5IKA A;  1WMW A;  5KSX F;  5ERN A;  4KVW A;  2AEL A;  3P5P A;  4RXA A;  4LIX A;  4OMG A;  4E1E A;  3M0G A;  3N6K F;  3KRP A;  3IPI A;  4KUX A;  3M9U A;  4EA0 A;  3WEJ A;  3KRO B;  1N22 A;  2O1O A;  3WCI A;  3NRI A;  4KFA A;  2F8C F;  3B7L A;  1RQI A;  4GAX A;  1HXC A;  3QQV A;  5ERM A;  1HM4 A;  3P5R A;  5HN7 A;  1YHL A;  5B00 A;  4EA2 A;  4OMH A;  1UBV A;  4N9U A;  4GP1 A;  4H5D F;  5IMN A;  1YYR A;  3ZL6 A;  3V1V A;  4HD1 A;  3M01 A;  3LMD A;  5IM1 A;  3DYF A;  2Q80 A;  4H5C F;  3ZMB A;  2F94 F;  1VG7 A;  3ACX A;  5DZ2 A;  3W7F A;  3TFP A;  5B0J A;  3KRC A;  3SDU A;  3N0G A;  4DI5 A;  4E9U A;  3N49 F;  3AQB B;  3KRA B;  4NFJ F;  4KQS A;  2PS5 A;  3WEG A;  1RQJ A;  2Z4V A;  4XQS F;  5IMP A;  5E8H A;  3VJA A;  3WEF A;  2F7M F;  2ONG A;  2E8T A;  5E8L A;  2DH4 A;  3WJO A;  1ZW5 A;  4NKE A;  1YYU A;  3LLW A;  5H9D A;  5B02 A;  3ICK A;  4KVD A;  5DGN F;  3LVS A;  4PVY F;  2E94 A;  5B0M A;  3OAC A;  2Z78 A;  3APZ A;  5EAT A;  4FP4 A;  3TFN A;  4P0V A;  2I19 A;  3CKE A;  4LZ0 A;  3VJ8 A;  1EZF A;  3KRO A;  5IL8 A;  2E90 A;  3G4D A;  1VG4 A;  2PS6 A;  3ADZ A;  3OYR A;  3RYE A;  4JZB A;  2E8W A;  1YYT A;  3VJD A;  4XQT F;  2ZCR A;  1N21 A;  3N0F A;  1RTR A;  1KIZ A;  3AE0 A;  5DHK A;  3N1V F;  4LZC A;  1HXG A;  2E4O A;  2Q9Y A;  3WCA A;  1N1B A;  2OPN A;  4LUU A;  4WK5 A;  3WC9 A;  1HXA A;  1WL3 A;  1UBW A;  5HN9 A;  3WCC A;  4RXD A;  2Z7H A;  4KPJ A;  1KIY A;  4LA6 A;  4P0X A;  2J5C A;  4LTV A;  1N24 A;  3WSA A;  1VG2 A;  3P41 A;  3LZ9 A;  5DIQ F;  3VJB A;  3ZMC A;  2OA6 A;  5IN8 A;  3SDT A;  3LDW A;  2Z4X A;  1HM7 A;  3NF2 A;  5CG6 A;  5IK0 A;  3ICM A;  1HX9 A;  4F62 A;  1VG3 A;  3WCF A;  5HN8 A;  2Q58 A;  3TS7 A;  3ICN A;  3Q30 A;  1VG6 A;  3QKC A;  4JXY A;  2FTZ A;  4MC3 A;  2E93 A;  5CG5 A;  5IL3 A;  3LK5 A;  5A0I A;  1N23 A;  3TFV A;  3M02 A;  3MZV A;  4OGU A;  3N1W F;  4OKM A;  3DYG A;  4KVY A;  5AEL A;  2Z4Z A;  1YV5 A;  3VJ9 A;  5B03 A;  2AZK A;  5JV2 F;  1UBY A;  4RNQ A;  3WCB A;  4RYP A;  3VJC A;  3SAE A;  5AHU B;  4P0W A;  3KBK A;  3KRF B;  2AZJ A;  3WJK A;  5DW7 A;  2Z50 A;  3WCL A;  5DHI A;  1YHK A;  2J1P A;  4GP2 A;  3KB9 A;  2AZL A;  2PS8 A;  4OKZ A;  3EZ3 A;  5DJR F;  3CP6 A;  3ZOU A;  2E91 A;  3LEE A;  2Z4Y A;  3WEH A;  4PVX F;  3OAB B;  4DHD A;  4KPD A;  5IVG A;  5B0K A;  2E8V A;  2ZEU A;  2PS7 A;  2E92 A;  2OPM A;  3PKO A;  4KKM A;  2Z4W A;  4E9Z A;  4LXW A;  4QXS F;  5DGS F;  3EGT A;  3ICZ A;  4XQR F;  4RXC A;  4KQU A;  1JFG A;  4NKF A;  4QPF A;  4EA1 A;  4ZQ8 A;  3RBM A;  4LPG F;  3S9V A;  1YHM A;  2F9K F;  2E95 A;  2ZCO A;  3PH7 A;  3ACW A;  3PYB A;  4LPH F;  3WCG A;  5ILD A;  3N45 F;  4DWG A;  5JV0 F;  4LFG A;  2ONH A;  3P8R A;  3VJE A;  5ILY A;  4L2X F;  5AYP A;  5ILJ A;  3TC1 A;  3KRA A;  3M00 A;  1DGP A;  5ILZ A;  1JFA A;  3Q2Q A;  3AQ0 A;  5EAS A;  3N3D A;  2ZY1 A;  3WE9 A;  1FPS A;  3SDQ A;  2F89 F;  1DI1 A;  2RAH A;  5I1U A;  5E8K A;  3AQC B;  3ZCD A;  2E8X A;  3NPR A;  3KRF A;  4KVI A;  1YYS A;  5ILK A;  5A0J A;  4K10 A;  4LLS A;  1WL2 A;  3Q1O A;  5B0I A;  5B01 A;  3OAC B;  4LFE A;  3PDE A;  3LOM A;  4NG6 A;  3DYH A;  1V4H A;  4FJQ A;  3OAB A;  3LGZ B;  4DZW A;  5JV1 F;  4LOB A;  4UMJ A;  3N5J F;  4JZX A;  2OGD A;  1V4I A;  1WKZ A;  5A0K A;  3NPK A;  1WY0 A;  3UCA A;  1UBX A;  4DXJ A;  2VF6 A;  5AFX A;  5ILH A;  4RXE A;  2Z7I A;  4H5E F;  1WL0 A;  3V1X A;  3WCE A;  3LJI A;  1N20 A;  5ERO A;  2P1C A;  3LGK A;  3WEK A;  3WSB A;  5DJV F;  4LFV F;  3BNY A;  1YYQ A;  3N5H F;  3WCD A;  3G4F A;  4NFI F;  4MC0 A;  3ASX A;  3WCM A;  5ER8 A;  3IBA A;  3N46 F;  4GA3 A;  2EWG A;  4LLT A;  4JYX A;  4JXN A;  5ILI A;  3KRP B;  3PYA A;  4Q23 A;  2Z52 A;  2H8O A;  5EAU A;  5DJP F;  5JA0 F;  2PS4 A;  4DEM F;  4LTZ A;  2ZEV A;  2J1O A;  3WCH A;  4F6X A;  2F8Z F;  5DGM F;  4KQ5 A;  2E8U A;  3WJN A;  4NUA A;  2Q9Z A;  2F92 F;  5C05 A;  3SDV A;  4DWB A;  4JVJ F;  1N1Z A;  1V4E A;  4NFK F;  2AEK A;  5IK6 A;  1YJ4 A;  3WEI A;  2FOR A;  2QIS A;  1V4K A;  4N1Z F;  1V4J A;  3BNX A;  3N3L F;  4F6V A;  3KRC B;  3LG5 A;  3RMG A;  3MAV A;  2ZCQ A;  5IK9 A;  3EFQ A;  5HNA A;  1YQ7 A;  3P8L A;  3RYW A;  1PS1 A; 
#chains in the Genus database with same CATH homology
 5IKH A;  3Q2Z A;  4KK2 A;  2ZCS A;  4LA5 A;  3V66 A;  5IMI A;  4KWD A;  5JUZ F;  5B0L A;  1WL1 A;  3SDR A;  3ACY A;  3WCJ A;  3LSN A;  3CC9 A;  4MC8 A;  3ID0 A;  4LZ3 A;  2AET A;  3S4J A;  5IKA A;  1WMW A;  5KSX F;  5ERN A;  4KVW A;  2AEL A;  3P5P A;  4RXA A;  4LIX A;  4OMG A;  4E1E A;  3M0G A;  3N6K F;  3KRP A;  3IPI A;  4KUX A;  3M9U A;  4EA0 A;  3WEJ A;  3KRO B;  1N22 A;  2O1O A;  3WCI A;  3NRI A;  4KFA A;  2F8C F;  3B7L A;  1RQI A;  4GAX A;  1HXC A;  3QQV A;  5ERM A;  1HM4 A;  3P5R A;  5HN7 A;  1YHL A;  5B00 A;  4EA2 A;  4OMH A;  1UBV A;  4N9U A;  4GP1 A;  4H5D F;  5IMN A;  1YYR A;  3ZL6 A;  3V1V A;  4HD1 A;  3M01 A;  3LMD A;  5IM1 A;  3DYF A;  2Q80 A;  4H5C F;  3ZMB A;  2F94 F;  1VG7 A;  3ACX A;  5DZ2 A;  3W7F A;  3TFP A;  5B0J A;  3KRC A;  3SDU A;  3N0G A;  4DI5 A;  4E9U A;  3N49 F;  3AQB B;  3KRA B;  4NFJ F;  4KQS A;  2PS5 A;  3WEG A;  1RQJ A;  2Z4V A;  4XQS F;  5IMP A;  5E8H A;  3VJA A;  3WEF A;  2F7M F;  2ONG A;  2E8T A;  5E8L A;  2DH4 A;  3WJO A;  1ZW5 A;  4NKE A;  1YYU A;  3LLW A;  5H9D A;  5B02 A;  3ICK A;  4KVD A;  5DGN F;  3LVS A;  4PVY F;  2E94 A;  5B0M A;  3OAC A;  2Z78 A;  3APZ A;  5EAT A;  4FP4 A;  3TFN A;  4P0V A;  2I19 A;  3CKE A;  4LZ0 A;  3VJ8 A;  1EZF A;  3KRO A;  5IL8 A;  2E90 A;  3G4D A;  1VG4 A;  2PS6 A;  3ADZ A;  3OYR A;  3RYE A;  4JZB A;  2E8W A;  1YYT A;  3VJD A;  4XQT F;  2ZCR A;  1N21 A;  3N0F A;  1RTR A;  1KIZ A;  3AE0 A;  5DHK A;  3N1V F;  4LZC A;  1HXG A;  2E4O A;  2Q9Y A;  3WCA A;  1N1B A;  2OPN A;  4LUU A;  4WK5 A;  3WC9 A;  1HXA A;  1WL3 A;  1UBW A;  5HN9 A;  3WCC A;  4RXD A;  2Z7H A;  4KPJ A;  1KIY A;  4LA6 A;  4P0X A;  2J5C A;  4LTV A;  1N24 A;  3WSA A;  1VG2 A;  3P41 A;  3LZ9 A;  5DIQ F;  3VJB A;  3ZMC A;  2OA6 A;  5IN8 A;  3SDT A;  3LDW A;  2Z4X A;  1HM7 A;  3NF2 A;  5CG6 A;  5IK0 A;  3ICM A;  1HX9 A;  4F62 A;  1VG3 A;  3WCF A;  5HN8 A;  2Q58 A;  3TS7 A;  3ICN A;  3Q30 A;  1VG6 A;  3QKC A;  4JXY A;  2FTZ A;  4MC3 A;  2E93 A;  5CG5 A;  5IL3 A;  3LK5 A;  5A0I A;  1N23 A;  3TFV A;  3M02 A;  3MZV A;  4OGU A;  3N1W F;  4OKM A;  3DYG A;  4KVY A;  5AEL A;  2Z4Z A;  1YV5 A;  3VJ9 A;  5B03 A;  2AZK A;  5JV2 F;  1UBY A;  4RNQ A;  3WCB A;  4RYP A;  3VJC A;  3SAE A;  5AHU B;  4P0W A;  3KBK A;  3KRF B;  2AZJ A;  3WJK A;  5DW7 A;  2Z50 A;  3WCL A;  5DHI A;  1YHK A;  2J1P A;  4GP2 A;  3KB9 A;  2AZL A;  2PS8 A;  4OKZ A;  3EZ3 A;  5DJR F;  3CP6 A;  3ZOU A;  2E91 A;  3LEE A;  2Z4Y A;  3WEH A;  4PVX F;  3OAB B;  4DHD A;  4KPD A;  5IVG A;  5B0K A;  2E8V A;  2ZEU A;  2PS7 A;  2E92 A;  2OPM A;  3PKO A;  4KKM A;  2Z4W A;  4E9Z A;  4LXW A;  4QXS F;  5DGS F;  3EGT A;  3ICZ A;  4XQR F;  4RXC A;  4KQU A;  1JFG A;  4NKF A;  4QPF A;  4EA1 A;  4ZQ8 A;  3RBM A;  4LPG F;  3S9V A;  1YHM A;  2F9K F;  2E95 A;  2ZCO A;  3PH7 A;  3ACW A;  3PYB A;  4LPH F;  3WCG A;  5ILD A;  3N45 F;  4DWG A;  5JV0 F;  4LFG A;  2ONH A;  3P8R A;  3VJE A;  5ILY A;  4L2X F;  5AYP A;  5ILJ A;  3TC1 A;  3KRA A;  3M00 A;  1DGP A;  5ILZ A;  1JFA A;  3Q2Q A;  3AQ0 A;  5EAS A;  3N3D A;  2ZY1 A;  3WE9 A;  1FPS A;  3SDQ A;  2F89 F;  1DI1 A;  2RAH A;  5I1U A;  5E8K A;  3AQC B;  3ZCD A;  2E8X A;  3NPR A;  3KRF A;  4KVI A;  1YYS A;  5ILK A;  5A0J A;  4K10 A;  4LLS A;  1WL2 A;  3Q1O A;  5B0I A;  5B01 A;  3OAC B;  4LFE A;  3PDE A;  3LOM A;  4NG6 A;  3DYH A;  1V4H A;  4FJQ A;  3OAB A;  3LGZ B;  4DZW A;  5JV1 F;  4LOB A;  4UMJ A;  3N5J F;  4JZX A;  2OGD A;  1V4I A;  1WKZ A;  5A0K A;  3NPK A;  1WY0 A;  3UCA A;  1UBX A;  4DXJ A;  2VF6 A;  5AFX A;  5ILH A;  4RXE A;  2Z7I A;  4H5E F;  1WL0 A;  3V1X A;  3WCE A;  3LJI A;  1N20 A;  5ERO A;  2P1C A;  3LGK A;  3WEK A;  3WSB A;  5DJV F;  4LFV F;  3BNY A;  1YYQ A;  3N5H F;  3WCD A;  3G4F A;  4NFI F;  4MC0 A;  3ASX A;  3WCM A;  5ER8 A;  3IBA A;  3N46 F;  4GA3 A;  2EWG A;  4LLT A;  4JYX A;  4JXN A;  5ILI A;  3KRP B;  3PYA A;  4Q23 A;  2Z52 A;  2H8O A;  5EAU A;  5DJP F;  5JA0 F;  2PS4 A;  4DEM F;  4LTZ A;  2ZEV A;  2J1O A;  3WCH A;  4F6X A;  2F8Z F;  5DGM F;  4KQ5 A;  2E8U A;  3WJN A;  4NUA A;  2Q9Z A;  2F92 F;  5C05 A;  3SDV A;  4DWB A;  4JVJ F;  1N1Z A;  1V4E A;  4NFK F;  2AEK A;  5IK6 A;  1YJ4 A;  3WEI A;  2FOR A;  2QIS A;  1V4K A;  4N1Z F;  1V4J A;  3BNX A;  3N3L F;  4F6V A;  3KRC B;  3LG5 A;  3RMG A;  3MAV A;  2ZCQ A;  5IK9 A;  3EFQ A;  5HNA A;  1YQ7 A;  3P8L A;  3RYW A;  1PS1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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