3WEJA

Crystal structure of the human squalene synthase f288a mutant in complex with presqualene pyrophosphate
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNACAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords Squalene synthase
publication title Structural insights into the catalytic mechanism of human squalene synthase
doi rcsb
source organism Homo sapiens
total genus 130
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wejA00
4LZ0A 2PS6A 3P5PA 1WL0A 3ZMBA 3ICKA 4PVXF 3WJNA 2VF6A 3KRPA 4H5EF 5ER8A 2I19A 3LOMA 5HN8A 3WCAA 5DGNF 5JUZF 4JXNA 5E8KA 3LK5A 3MAVA 4P0WA 1V4JA 4NFJF 4LPHF 3LG5A 5EAUA 4KUXA 3N6KF 3G4DA 1YYUA 4F62A 3LDWA 2ZEUA 4DEMF 4LUUA 2ZY1A 5DHIA 3WJKA 4LLSA 2E95A 5DGSF 4JYXA 3PDEA 4GP2A 1YHKA 5IMNA 3RYWA 5JV2F 3TFNA 3M01A 2ONHA 4OMHA 5ILIA 1EZFA 3DYHA 2PS5A 5EATA 5IK0A 4LFEA 5C05A 4H5CF 3NPKA 4LOBA 3WCMA 3SDQA 3WCFA 3WSBA 3IPIA 1N1ZA 3Q30A 3LMDA 4P0VA 3N0FA 1DI1A 2PS8A 1UBVA 5DHKA 3QQVA 4F6VA 3SDRA 3NPRA 1RQIA 3N5JF 2AELA 4JXYA 4E1EA 3MZVA 1VG6A 2FTZA 2F8CF 5IVGA 3WEKA 3KRAB 1HXCA 5B0KA 2AZLA 3LLWA 3N5HF 5DIQF 3ACXA 2ZCQA 5B01A 4P0XA 3KROA 4KKMA 3OABA 3PKOA 4GA3A 5B0JA 3W7FA 5B0IA 4NFIF 2F9KF 4EA1A 2ZCOA 1JFGA 1PS1A 3WEFA 5IMPA 5HN9A 2F8ZF 2ONGA 5AYPA 5IMIA 5DJRF 5JA0F 5B03A 2DH4A 4RYPA 2Z78A 3ZMCA 3M00A 5ERMA 3WSAA 4LFGA 4DHDA 3AE0A 3G4FA 3VJEA 1YYQA 3KRPB 3PYBA 3TC1A 2E92A 4GP1A 1RQJA 1VG2A 4KVIA 3WCJA 2AEKA 2AZKA 3AQBB 3VJBA 3CKEA 1WKZA 5ILHA 4LZCA 3KRFA 4NKEA 5AFXA 5CG5A 2Q80A 2J1OA 5IK9A 5EROA 1YQ7A 2E8VA 3ICMA 3ID0A 5A0JA 1JFAA 4ZQ8A 2J1PA 4EA2A 4OGUA 3WJOA 3DYFA 2F92F 4LFVF 3N45F 5CG6A 2E90A 3QKCA 3VJ9A 1V4IA 2PS7A 3RYEA 2E4OA 3VJDA 5A0KA 3VJ8A 1HXGA 3P8LA 4N1ZF 2Z4XA 2FORA 3WC9A 1V4HA 5B02A 4KPDA 3TS7A 2F89F 3N49F 5B00A 3LGKA 5ILYA 5DJPF 1WL1A 1YJ4A 1VG4A 4RNQA 5A0IA 4DI5A 4MC3A 4KQSA 1N23A 4JVJF 3WE9A 4Q23A 2OGDA 5DZ2A 5JV1F 3M02A 3VJAA 5AELA 4NKFA 4OKMA 4XQRF 4DWGA 2Q9YA 4KVYA 2OPMA 3CC9A 1KIZA 4JZXA 4NFKF 1V4KA 4LXWA 4KVDA 3OACA 2Q58A 2Q9ZA 2Z7HA 5IM1A 3N3DA 4PVYF 3UCAA 5IL3A 5ILKA 3ADZA 3EFQA 4RXDA 1YV5A 4LA5A 3WEIA 3V1XA 4DWBA 2H8OA 4KPJA 4FP4A 2Z52A 4NUAA 1N21A 2EWGA 4H5DF 3ZCDA 3KRCA 3RMGA 3LSNA 3V66A 1UBWA 3EGTA 4MC0A 5ILDA 3SDTA 1N22A 1UBYA 5B0MA 3ACWA 2OA6A 3N46F 3S9VA 3DYGA 5IKHA 4OMGA 3WCHA 3LGZB 4HD1A 3CP6A 4LIXA 5E8LA 5HN7A 3P41A 3WCGA 5I1UA 2O1OA 1YYSA 1N1BA 3B7LA 3AQ0A 3OYRA 4LTZA 1YYRA 3APZA 5ILZA 3KRFB 3M9UA 4RXAA 3ASXA 3KB9A 3LVSA 3PH7A 3V1VA 2E94A 2Z4VA 3LZ9A 3LEEA 1YHLA 3WCCA 1FPSA 4LPGF 5HNAA 4LA6A 1VG7A 4DXJA 5IN8A 2Z7IA 2AETA 3TFPA 3WCDA 2J5CA 3KBKA 1N24A 2QISA 4RXEA 1HXAA 3NF2A 3SDVA 4QXSF 4QPFA 3VJCA 1WL2A 2E8XA 4F6XA 2F7MF 4KFAA 4UMJA 3S4JA 4XQTF 1V4EA 2AZJA 1KIYA 4LLTA 4L2XF 1HM4A 5E8HA 4LTVA 3ZOUA 4WK5A 4XQSF 2Z4ZA 2E93A 2PS4A 4E9UA 1N20A 4OKZA 2E91A 3LJIA 3WCBA 3WEGA 5ERNA 3RBMA 1WL3A 3WCIA 3SDUA 2OPNA 3N1VF 2E8WA 5IK6A 2Z4WA 4DZWA 3ICNA 5AHUB 4KQUA 3WEHA 3AQCB 2E8TA 4EA0A 5DW7A 3PYAA 3P5RA 2ZCRA 3M0GA 2ZCSA 3KROB 3OACB 3TFVA 4RXCA 3OABB 4N9UA 1UBXA 3IBAA 4KQ5A 3ICZA 5B0LA 2P1CA 4KWDA 3ZL6A 4NG6A 1YHMA 3BNYA 1DGPA 5JV0F 4FJQA 1HM7A 2ZEVA 3EZ3A 3KRAA 5H9DA 1WY0A 4MC8A 3N3LF 5DJVF 1HX9A 3BNXA 3KRCB 5IL8A 5EASA 3SAEA 3Q1OA 2E8UA 2Z50A 2RAHA 2Z4YA 5IKAA 3WCLA 3N1WF 4JZBA 3ACYA 4E9ZA 3NRIA 4K10A 3N0GA 5KSXF 3WEJA 4LZ3A 1WMWA 3Q2QA 3Q2ZA 1RTRA 4KVWA 5ILJA 2F94F 4GAXA 1VG3A 3WCEA 1YYTA 3P8RA 5DGMF 1ZW5A 4KK2A
chains in the Genus database with same CATH superfamily
4LZ0A 2PS6A 3P5PA 1WL0A 3ZMBA 3ICKA 4PVXF 3WJNA 2VF6A 3KRPA 4H5EF 5ER8A 2I19A 3LOMA 5HN8A 3WCAA 5DGNF 5JUZF 4JXNA 5E8KA 3LK5A 3MAVA 4P0WA 1V4JA 4NFJF 4LPHF 3LG5A 5EAUA 4KUXA 3N6KF 3G4DA 1YYUA 4F62A 3LDWA 2ZEUA 4DEMF 4LUUA 2ZY1A 5DHIA 3WJKA 4LLSA 2E95A 5DGSF 4JYXA 3PDEA 4GP2A 1YHKA 5IMNA 3RYWA 5JV2F 3TFNA 3M01A 2ONHA 4OMHA 5ILIA 1EZFA 3DYHA 2PS5A 5EATA 5IK0A 4LFEA 5C05A 4H5CF 3NPKA 4LOBA 3WCMA 3SDQA 3WCFA 3WSBA 3IPIA 1N1ZA 3Q30A 3LMDA 4P0VA 3N0FA 1DI1A 2PS8A 1UBVA 5DHKA 3QQVA 4F6VA 3SDRA 3NPRA 1RQIA 3N5JF 2AELA 4JXYA 4E1EA 3MZVA 1VG6A 2FTZA 2F8CF 5IVGA 3WEKA 3KRAB 1HXCA 5B0KA 2AZLA 3LLWA 3N5HF 5DIQF 3ACXA 2ZCQA 5B01A 4P0XA 3KROA 4KKMA 3OABA 3PKOA 4GA3A 5B0JA 3W7FA 5B0IA 4NFIF 2F9KF 4EA1A 2ZCOA 1JFGA 1PS1A 3WEFA 5IMPA 5HN9A 2F8ZF 2ONGA 5AYPA 5IMIA 5DJRF 5JA0F 5B03A 2DH4A 4RYPA 2Z78A 3ZMCA 3M00A 5ERMA 3WSAA 4LFGA 4DHDA 3AE0A 3G4FA 3VJEA 1YYQA 3KRPB 3PYBA 3TC1A 2E92A 4GP1A 1RQJA 1VG2A 4KVIA 3WCJA 2AEKA 2AZKA 3AQBB 3VJBA 3CKEA 1WKZA 5ILHA 4LZCA 3KRFA 4NKEA 5AFXA 5CG5A 2Q80A 2J1OA 5IK9A 5EROA 1YQ7A 2E8VA 3ICMA 3ID0A 5A0JA 1JFAA 4ZQ8A 2J1PA 4EA2A 4OGUA 3WJOA 3DYFA 2F92F 4LFVF 3N45F 5CG6A 2E90A 3QKCA 3VJ9A 1V4IA 2PS7A 3RYEA 2E4OA 3VJDA 5A0KA 3VJ8A 1HXGA 3P8LA 4N1ZF 2Z4XA 2FORA 3WC9A 1V4HA 5B02A 4KPDA 3TS7A 2F89F 3N49F 5B00A 3LGKA 5ILYA 5DJPF 1WL1A 1YJ4A 1VG4A 4RNQA 5A0IA 4DI5A 4MC3A 4KQSA 1N23A 4JVJF 3WE9A 4Q23A 2OGDA 5DZ2A 5JV1F 3M02A 3VJAA 5AELA 4NKFA 4OKMA 4XQRF 4DWGA 2Q9YA 4KVYA 2OPMA 3CC9A 1KIZA 4JZXA 4NFKF 1V4KA 4LXWA 4KVDA 3OACA 2Q58A 2Q9ZA 2Z7HA 5IM1A 3N3DA 4PVYF 3UCAA 5IL3A 5ILKA 3ADZA 3EFQA 4RXDA 1YV5A 4LA5A 3WEIA 3V1XA 4DWBA 2H8OA 4KPJA 4FP4A 2Z52A 4NUAA 1N21A 2EWGA 4H5DF 3ZCDA 3KRCA 3RMGA 3LSNA 3V66A 1UBWA 3EGTA 4MC0A 5ILDA 3SDTA 1N22A 1UBYA 5B0MA 3ACWA 2OA6A 3N46F 3S9VA 3DYGA 5IKHA 4OMGA 3WCHA 3LGZB 4HD1A 3CP6A 4LIXA 5E8LA 5HN7A 3P41A 3WCGA 5I1UA 2O1OA 1YYSA 1N1BA 3B7LA 3AQ0A 3OYRA 4LTZA 1YYRA 3APZA 5ILZA 3KRFB 3M9UA 4RXAA 3ASXA 3KB9A 3LVSA 3PH7A 3V1VA 2E94A 2Z4VA 3LZ9A 3LEEA 1YHLA 3WCCA 1FPSA 4LPGF 5HNAA 4LA6A 1VG7A 4DXJA 5IN8A 2Z7IA 2AETA 3TFPA 3WCDA 2J5CA 3KBKA 1N24A 2QISA 4RXEA 1HXAA 3NF2A 3SDVA 4QXSF 4QPFA 3VJCA 1WL2A 2E8XA 4F6XA 2F7MF 4KFAA 4UMJA 3S4JA 4XQTF 1V4EA 2AZJA 1KIYA 4LLTA 4L2XF 1HM4A 5E8HA 4LTVA 3ZOUA 4WK5A 4XQSF 2Z4ZA 2E93A 2PS4A 4E9UA 1N20A 4OKZA 2E91A 3LJIA 3WCBA 3WEGA 5ERNA 3RBMA 1WL3A 3WCIA 3SDUA 2OPNA 3N1VF 2E8WA 5IK6A 2Z4WA 4DZWA 3ICNA 5AHUB 4KQUA 3WEHA 3AQCB 2E8TA 4EA0A 5DW7A 3PYAA 3P5RA 2ZCRA 3M0GA 2ZCSA 3KROB 3OACB 3TFVA 4RXCA 3OABB 4N9UA 1UBXA 3IBAA 4KQ5A 3ICZA 5B0LA 2P1CA 4KWDA 3ZL6A 4NG6A 1YHMA 3BNYA 1DGPA 5JV0F 4FJQA 1HM7A 2ZEVA 3EZ3A 3KRAA 5H9DA 1WY0A 4MC8A 3N3LF 5DJVF 1HX9A 3BNXA 3KRCB 5IL8A 5EASA 3SAEA 3Q1OA 2E8UA 2Z50A 2RAHA 2Z4YA 5IKAA 3WCLA 3N1WF 4JZBA 3ACYA 4E9ZA 3NRIA 4K10A 3N0GA 5KSXF 3WEJA 4LZ3A 1WMWA 3Q2QA 3Q2ZA 1RTRA 4KVWA 5ILJA 2F94F 4GAXA 1VG3A 3WCEA 1YYTA 3P8RA 5DGMF 1ZW5A 4KK2A
chains in the Genus database with same CATH topology
4LZ0A 2PS6A 3P5PA 1WL0A 3ZMBA 3ICKA 4PVXF 3WJNA 2VF6A 3KRPA 4H5EF 5ER8A 2I19A 3LOMA 5HN8A 3WCAA 5DGNF 5JUZF 4JXNA 5E8KA 3LK5A 3MAVA 4P0WA 1V4JA 4NFJF 4LPHF 3LG5A 5EAUA 4KUXA 3N6KF 3G4DA 1YYUA 4F62A 3LDWA 2ZEUA 4DEMF 4LUUA 2ZY1A 5DHIA 3WJKA 4LLSA 2E95A 5DGSF 4JYXA 3PDEA 4GP2A 1YHKA 5IMNA 3RYWA 5JV2F 3TFNA 3M01A 2ONHA 4OMHA 5ILIA 1EZFA 3DYHA 2PS5A 5EATA 5IK0A 4LFEA 5C05A 4H5CF 3NPKA 4LOBA 3WCMA 3SDQA 3WCFA 3WSBA 3IPIA 1N1ZA 3Q30A 3LMDA 4P0VA 3N0FA 1DI1A 2PS8A 1UBVA 5DHKA 3QQVA 4F6VA 3SDRA 3NPRA 1RQIA 3N5JF 2AELA 4JXYA 4E1EA 3MZVA 1VG6A 2FTZA 2F8CF 5IVGA 3WEKA 3KRAB 1HXCA 5B0KA 2AZLA 3LLWA 3N5HF 5DIQF 3ACXA 2ZCQA 5B01A 4P0XA 3KROA 4KKMA 3OABA 3PKOA 4GA3A 5B0JA 3W7FA 5B0IA 4NFIF 2F9KF 4EA1A 2ZCOA 1JFGA 1PS1A 3WEFA 5IMPA 5HN9A 2F8ZF 2ONGA 5AYPA 5IMIA 5DJRF 5JA0F 5B03A 2DH4A 4RYPA 2Z78A 3ZMCA 3M00A 5ERMA 3WSAA 4LFGA 4DHDA 3AE0A 3G4FA 3VJEA 1YYQA 3KRPB 3PYBA 3TC1A 2E92A 4GP1A 1RQJA 1VG2A 4KVIA 3WCJA 2AEKA 2AZKA 3AQBB 3VJBA 3CKEA 1WKZA 5ILHA 4LZCA 3KRFA 4NKEA 5AFXA 5CG5A 2Q80A 2J1OA 5IK9A 5EROA 1YQ7A 2E8VA 3ICMA 3ID0A 5A0JA 1JFAA 4ZQ8A 2J1PA 4EA2A 4OGUA 3WJOA 3DYFA 2F92F 4LFVF 3N45F 5CG6A 2E90A 3QKCA 3VJ9A 1V4IA 2PS7A 3RYEA 2E4OA 3VJDA 5A0KA 3VJ8A 1HXGA 3P8LA 4N1ZF 2Z4XA 2FORA 3WC9A 1V4HA 5B02A 4KPDA 3TS7A 2F89F 3N49F 5B00A 3LGKA 5ILYA 5DJPF 1WL1A 1YJ4A 1VG4A 4RNQA 5A0IA 4DI5A 4MC3A 4KQSA 1N23A 4JVJF 3WE9A 4Q23A 2OGDA 5DZ2A 5JV1F 3M02A 3VJAA 5AELA 4NKFA 4OKMA 4XQRF 4DWGA 2Q9YA 4KVYA 2OPMA 3CC9A 1KIZA 4JZXA 4NFKF 1V4KA 4LXWA 4KVDA 3OACA 2Q58A 2Q9ZA 2Z7HA 5IM1A 3N3DA 4PVYF 3UCAA 5IL3A 5ILKA 3ADZA 3EFQA 4RXDA 1YV5A 4LA5A 3WEIA 3V1XA 4DWBA 2H8OA 4KPJA 4FP4A 2Z52A 4NUAA 1N21A 2EWGA 4H5DF 3ZCDA 3KRCA 3RMGA 3LSNA 3V66A 1UBWA 3EGTA 4MC0A 5ILDA 3SDTA 1N22A 1UBYA 5B0MA 3ACWA 2OA6A 3N46F 3S9VA 3DYGA 5IKHA 4OMGA 3WCHA 3LGZB 4HD1A 3CP6A 4LIXA 5E8LA 5HN7A 3P41A 3WCGA 5I1UA 2O1OA 1YYSA 1N1BA 3B7LA 3AQ0A 3OYRA 4LTZA 1YYRA 3APZA 5ILZA 3KRFB 3M9UA 4RXAA 3ASXA 3KB9A 3LVSA 3PH7A 3V1VA 2E94A 2Z4VA 3LZ9A 3LEEA 1YHLA 3WCCA 1FPSA 4LPGF 5HNAA 4LA6A 1VG7A 4DXJA 5IN8A 2Z7IA 2AETA 3TFPA 3WCDA 2J5CA 3KBKA 1N24A 2QISA 4RXEA 1HXAA 3NF2A 3SDVA 4QXSF 4QPFA 3VJCA 1WL2A 2E8XA 4F6XA 2F7MF 4KFAA 4UMJA 3S4JA 4XQTF 1V4EA 2AZJA 1KIYA 4LLTA 4L2XF 1HM4A 5E8HA 4LTVA 3ZOUA 4WK5A 4XQSF 2Z4ZA 2E93A 2PS4A 4E9UA 1N20A 4OKZA 2E91A 3LJIA 3WCBA 3WEGA 5ERNA 3RBMA 1WL3A 3WCIA 3SDUA 2OPNA 3N1VF 2E8WA 5IK6A 2Z4WA 4DZWA 3ICNA 5AHUB 4KQUA 3WEHA 3AQCB 2E8TA 4EA0A 5DW7A 3PYAA 3P5RA 2ZCRA 3M0GA 2ZCSA 3KROB 3OACB 3TFVA 4RXCA 3OABB 4N9UA 1UBXA 3IBAA 4KQ5A 3ICZA 5B0LA 2P1CA 4KWDA 3ZL6A 4NG6A 1YHMA 3BNYA 1DGPA 5JV0F 4FJQA 1HM7A 2ZEVA 3EZ3A 3KRAA 5H9DA 1WY0A 4MC8A 3N3LF 5DJVF 1HX9A 3BNXA 3KRCB 5IL8A 5EASA 3SAEA 3Q1OA 2E8UA 2Z50A 2RAHA 2Z4YA 5IKAA 3WCLA 3N1WF 4JZBA 3ACYA 4E9ZA 3NRIA 4K10A 3N0GA 5KSXF 3WEJA 4LZ3A 1WMWA 3Q2QA 3Q2ZA 1RTRA 4KVWA 5ILJA 2F94F 4GAXA 1VG3A 3WCEA 1YYTA 3P8RA 5DGMF 1ZW5A 4KK2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LZ0 A;  2PS6 A;  3P5P A;  1WL0 A;  3ZMB A;  3ICK A;  4PVX F;  3WJN A;  2VF6 A;  3KRP A;  4H5E F;  5ER8 A;  2I19 A;  3LOM A;  5HN8 A;  3WCA A;  5DGN F;  5JUZ F;  4JXN A;  5E8K A;  3LK5 A;  3MAV A;  4P0W A;  1V4J A;  4NFJ F;  4LPH F;  3LG5 A;  5EAU A;  4KUX A;  3N6K F;  3G4D A;  1YYU A;  4F62 A;  3LDW A;  2ZEU A;  4DEM F;  4LUU A;  2ZY1 A;  5DHI A;  3WJK A;  4LLS A;  2E95 A;  5DGS F;  4JYX A;  3PDE A;  4GP2 A;  1YHK A;  5IMN A;  3RYW A;  5JV2 F;  3TFN A;  3M01 A;  2ONH A;  4OMH A;  5ILI A;  1EZF A;  3DYH A;  2PS5 A;  5EAT A;  5IK0 A;  4LFE A;  5C05 A;  4H5C F;  3NPK A;  4LOB A;  3WCM A;  3SDQ A;  3WCF A;  3WSB A;  3IPI A;  1N1Z A;  3Q30 A;  3LMD A;  4P0V A;  3N0F A;  1DI1 A;  2PS8 A;  1UBV A;  5DHK A;  3QQV A;  4F6V A;  3SDR A;  3NPR A;  1RQI A;  3N5J F;  2AEL A;  4JXY A;  4E1E A;  3MZV A;  1VG6 A;  2FTZ A;  2F8C F;  5IVG A;  3WEK A;  3KRA B;  1HXC A;  5B0K A;  2AZL A;  3LLW A;  3N5H F;  5DIQ F;  3ACX A;  2ZCQ A;  5B01 A;  4P0X A;  3KRO A;  4KKM A;  3OAB A;  3PKO A;  4GA3 A;  5B0J A;  3W7F A;  5B0I A;  4NFI F;  2F9K F;  4EA1 A;  2ZCO A;  1JFG A;  1PS1 A;  3WEF A;  5IMP A;  5HN9 A;  2F8Z F;  2ONG A;  5AYP A;  5IMI A;  5DJR F;  5JA0 F;  5B03 A;  2DH4 A;  4RYP A;  2Z78 A;  3ZMC A;  3M00 A;  5ERM A;  3WSA A;  4LFG A;  4DHD A;  3AE0 A;  3G4F A;  3VJE A;  1YYQ A;  3KRP B;  3PYB A;  3TC1 A;  2E92 A;  4GP1 A;  1RQJ A;  1VG2 A;  4KVI A;  3WCJ A;  2AEK A;  2AZK A;  3AQB B;  3VJB A;  3CKE A;  1WKZ A;  5ILH A;  4LZC A;  3KRF A;  4NKE A;  5AFX A;  5CG5 A;  2Q80 A;  2J1O A;  5IK9 A;  5ERO A;  1YQ7 A;  2E8V A;  3ICM A;  3ID0 A;  5A0J A;  1JFA A;  4ZQ8 A;  2J1P A;  4EA2 A;  4OGU A;  3WJO A;  3DYF A;  2F92 F;  4LFV F;  3N45 F;  5CG6 A;  2E90 A;  3QKC A;  3VJ9 A;  1V4I A;  2PS7 A;  3RYE A;  2E4O A;  3VJD A;  5A0K A;  3VJ8 A;  1HXG A;  3P8L A;  4N1Z F;  2Z4X A;  2FOR A;  3WC9 A;  1V4H A;  5B02 A;  4KPD A;  3TS7 A;  2F89 F;  3N49 F;  5B00 A;  3LGK A;  5ILY A;  5DJP F;  1WL1 A;  1YJ4 A;  1VG4 A;  4RNQ A;  5A0I A;  4DI5 A;  4MC3 A;  4KQS A;  1N23 A;  4JVJ F;  3WE9 A;  4Q23 A;  2OGD A;  5DZ2 A;  5JV1 F;  3M02 A;  3VJA A;  5AEL A;  4NKF A;  4OKM A;  4XQR F;  4DWG A;  2Q9Y A;  4KVY A;  2OPM A;  3CC9 A;  1KIZ A;  4JZX A;  4NFK F;  1V4K A;  4LXW A;  4KVD A;  3OAC A;  2Q58 A;  2Q9Z A;  2Z7H A;  5IM1 A;  3N3D A;  4PVY F;  3UCA A;  5IL3 A;  5ILK A;  3ADZ A;  3EFQ A;  4RXD A;  1YV5 A;  4LA5 A;  3WEI A;  3V1X A;  4DWB A;  2H8O A;  4KPJ A;  4FP4 A;  2Z52 A;  4NUA A;  1N21 A;  2EWG A;  4H5D F;  3ZCD A;  3KRC A;  3RMG A;  3LSN A;  3V66 A;  1UBW A;  3EGT A;  4MC0 A;  5ILD A;  3SDT A;  1N22 A;  1UBY A;  5B0M A;  3ACW A;  2OA6 A;  3N46 F;  3S9V A;  3DYG A;  5IKH A;  4OMG A;  3WCH A;  3LGZ B;  4HD1 A;  3CP6 A;  4LIX A;  5E8L A;  5HN7 A;  3P41 A;  3WCG A;  5I1U A;  2O1O A;  1YYS A;  1N1B A;  3B7L A;  3AQ0 A;  3OYR A;  4LTZ A;  1YYR A;  3APZ A;  5ILZ A;  3KRF B;  3M9U A;  4RXA A;  3ASX A;  3KB9 A;  3LVS A;  3PH7 A;  3V1V A;  2E94 A;  2Z4V A;  3LZ9 A;  3LEE A;  1YHL A;  3WCC A;  1FPS A;  4LPG F;  5HNA A;  4LA6 A;  1VG7 A;  4DXJ A;  5IN8 A;  2Z7I A;  2AET A;  3TFP A;  3WCD A;  2J5C A;  3KBK A;  1N24 A;  2QIS A;  4RXE A;  1HXA A;  3NF2 A;  3SDV A;  4QXS F;  4QPF A;  3VJC A;  1WL2 A;  2E8X A;  4F6X A;  2F7M F;  4KFA A;  4UMJ A;  3S4J A;  4XQT F;  1V4E A;  2AZJ A;  1KIY A;  4LLT A;  4L2X F;  1HM4 A;  5E8H A;  4LTV A;  3ZOU A;  4WK5 A;  4XQS F;  2Z4Z A;  2E93 A;  2PS4 A;  4E9U A;  1N20 A;  4OKZ A;  2E91 A;  3LJI A;  3WCB A;  3WEG A;  5ERN A;  3RBM A;  1WL3 A;  3WCI A;  3SDU A;  2OPN A;  3N1V F;  2E8W A;  5IK6 A;  2Z4W A;  4DZW A;  3ICN A;  5AHU B;  4KQU A;  3WEH A;  3AQC B;  2E8T A;  4EA0 A;  5DW7 A;  3PYA A;  3P5R A;  2ZCR A;  3M0G A;  2ZCS A;  3KRO B;  3OAC B;  3TFV A;  4RXC A;  3OAB B;  4N9U A;  1UBX A;  3IBA A;  4KQ5 A;  3ICZ A;  5B0L A;  2P1C A;  4KWD A;  3ZL6 A;  4NG6 A;  1YHM A;  3BNY A;  1DGP A;  5JV0 F;  4FJQ A;  1HM7 A;  2ZEV A;  3EZ3 A;  3KRA A;  5H9D A;  1WY0 A;  4MC8 A;  3N3L F;  5DJV F;  1HX9 A;  3BNX A;  3KRC B;  5IL8 A;  5EAS A;  3SAE A;  3Q1O A;  2E8U A;  2Z50 A;  2RAH A;  2Z4Y A;  5IKA A;  3WCL A;  3N1W F;  4JZB A;  3ACY A;  4E9Z A;  3NRI A;  4K10 A;  3N0G A;  5KSX F;  3WEJ A;  4LZ3 A;  1WMW A;  3Q2Q A;  3Q2Z A;  1RTR A;  4KVW A;  5ILJ A;  2F94 F;  4GAX A;  1VG3 A;  3WCE A;  1YYT A;  3P8R A;  5DGM F;  1ZW5 A;  4KK2 A; 
#chains in the Genus database with same CATH topology
 4LZ0 A;  2PS6 A;  3P5P A;  1WL0 A;  3ZMB A;  3ICK A;  4PVX F;  3WJN A;  2VF6 A;  3KRP A;  4H5E F;  5ER8 A;  2I19 A;  3LOM A;  5HN8 A;  3WCA A;  5DGN F;  5JUZ F;  4JXN A;  5E8K A;  3LK5 A;  3MAV A;  4P0W A;  1V4J A;  4NFJ F;  4LPH F;  3LG5 A;  5EAU A;  4KUX A;  3N6K F;  3G4D A;  1YYU A;  4F62 A;  3LDW A;  2ZEU A;  4DEM F;  4LUU A;  2ZY1 A;  5DHI A;  3WJK A;  4LLS A;  2E95 A;  5DGS F;  4JYX A;  3PDE A;  4GP2 A;  1YHK A;  5IMN A;  3RYW A;  5JV2 F;  3TFN A;  3M01 A;  2ONH A;  4OMH A;  5ILI A;  1EZF A;  3DYH A;  2PS5 A;  5EAT A;  5IK0 A;  4LFE A;  5C05 A;  4H5C F;  3NPK A;  4LOB A;  3WCM A;  3SDQ A;  3WCF A;  3WSB A;  3IPI A;  1N1Z A;  3Q30 A;  3LMD A;  4P0V A;  3N0F A;  1DI1 A;  2PS8 A;  1UBV A;  5DHK A;  3QQV A;  4F6V A;  3SDR A;  3NPR A;  1RQI A;  3N5J F;  2AEL A;  4JXY A;  4E1E A;  3MZV A;  1VG6 A;  2FTZ A;  2F8C F;  5IVG A;  3WEK A;  3KRA B;  1HXC A;  5B0K A;  2AZL A;  3LLW A;  3N5H F;  5DIQ F;  3ACX A;  2ZCQ A;  5B01 A;  4P0X A;  3KRO A;  4KKM A;  3OAB A;  3PKO A;  4GA3 A;  5B0J A;  3W7F A;  5B0I A;  4NFI F;  2F9K F;  4EA1 A;  2ZCO A;  1JFG A;  1PS1 A;  3WEF A;  5IMP A;  5HN9 A;  2F8Z F;  2ONG A;  5AYP A;  5IMI A;  5DJR F;  5JA0 F;  5B03 A;  2DH4 A;  4RYP A;  2Z78 A;  3ZMC A;  3M00 A;  5ERM A;  3WSA A;  4LFG A;  4DHD A;  3AE0 A;  3G4F A;  3VJE A;  1YYQ A;  3KRP B;  3PYB A;  3TC1 A;  2E92 A;  4GP1 A;  1RQJ A;  1VG2 A;  4KVI A;  3WCJ A;  2AEK A;  2AZK A;  3AQB B;  3VJB A;  3CKE A;  1WKZ A;  5ILH A;  4LZC A;  3KRF A;  4NKE A;  5AFX A;  5CG5 A;  2Q80 A;  2J1O A;  5IK9 A;  5ERO A;  1YQ7 A;  2E8V A;  3ICM A;  3ID0 A;  5A0J A;  1JFA A;  4ZQ8 A;  2J1P A;  4EA2 A;  4OGU A;  3WJO A;  3DYF A;  2F92 F;  4LFV F;  3N45 F;  5CG6 A;  2E90 A;  3QKC A;  3VJ9 A;  1V4I A;  2PS7 A;  3RYE A;  2E4O A;  3VJD A;  5A0K A;  3VJ8 A;  1HXG A;  3P8L A;  4N1Z F;  2Z4X A;  2FOR A;  3WC9 A;  1V4H A;  5B02 A;  4KPD A;  3TS7 A;  2F89 F;  3N49 F;  5B00 A;  3LGK A;  5ILY A;  5DJP F;  1WL1 A;  1YJ4 A;  1VG4 A;  4RNQ A;  5A0I A;  4DI5 A;  4MC3 A;  4KQS A;  1N23 A;  4JVJ F;  3WE9 A;  4Q23 A;  2OGD A;  5DZ2 A;  5JV1 F;  3M02 A;  3VJA A;  5AEL A;  4NKF A;  4OKM A;  4XQR F;  4DWG A;  2Q9Y A;  4KVY A;  2OPM A;  3CC9 A;  1KIZ A;  4JZX A;  4NFK F;  1V4K A;  4LXW A;  4KVD A;  3OAC A;  2Q58 A;  2Q9Z A;  2Z7H A;  5IM1 A;  3N3D A;  4PVY F;  3UCA A;  5IL3 A;  5ILK A;  3ADZ A;  3EFQ A;  4RXD A;  1YV5 A;  4LA5 A;  3WEI A;  3V1X A;  4DWB A;  2H8O A;  4KPJ A;  4FP4 A;  2Z52 A;  4NUA A;  1N21 A;  2EWG A;  4H5D F;  3ZCD A;  3KRC A;  3RMG A;  3LSN A;  3V66 A;  1UBW A;  3EGT A;  4MC0 A;  5ILD A;  3SDT A;  1N22 A;  1UBY A;  5B0M A;  3ACW A;  2OA6 A;  3N46 F;  3S9V A;  3DYG A;  5IKH A;  4OMG A;  3WCH A;  3LGZ B;  4HD1 A;  3CP6 A;  4LIX A;  5E8L A;  5HN7 A;  3P41 A;  3WCG A;  5I1U A;  2O1O A;  1YYS A;  1N1B A;  3B7L A;  3AQ0 A;  3OYR A;  4LTZ A;  1YYR A;  3APZ A;  5ILZ A;  3KRF B;  3M9U A;  4RXA A;  3ASX A;  3KB9 A;  3LVS A;  3PH7 A;  3V1V A;  2E94 A;  2Z4V A;  3LZ9 A;  3LEE A;  1YHL A;  3WCC A;  1FPS A;  4LPG F;  5HNA A;  4LA6 A;  1VG7 A;  4DXJ A;  5IN8 A;  2Z7I A;  2AET A;  3TFP A;  3WCD A;  2J5C A;  3KBK A;  1N24 A;  2QIS A;  4RXE A;  1HXA A;  3NF2 A;  3SDV A;  4QXS F;  4QPF A;  3VJC A;  1WL2 A;  2E8X A;  4F6X A;  2F7M F;  4KFA A;  4UMJ A;  3S4J A;  4XQT F;  1V4E A;  2AZJ A;  1KIY A;  4LLT A;  4L2X F;  1HM4 A;  5E8H A;  4LTV A;  3ZOU A;  4WK5 A;  4XQS F;  2Z4Z A;  2E93 A;  2PS4 A;  4E9U A;  1N20 A;  4OKZ A;  2E91 A;  3LJI A;  3WCB A;  3WEG A;  5ERN A;  3RBM A;  1WL3 A;  3WCI A;  3SDU A;  2OPN A;  3N1V F;  2E8W A;  5IK6 A;  2Z4W A;  4DZW A;  3ICN A;  5AHU B;  4KQU A;  3WEH A;  3AQC B;  2E8T A;  4EA0 A;  5DW7 A;  3PYA A;  3P5R A;  2ZCR A;  3M0G A;  2ZCS A;  3KRO B;  3OAC B;  3TFV A;  4RXC A;  3OAB B;  4N9U A;  1UBX A;  3IBA A;  4KQ5 A;  3ICZ A;  5B0L A;  2P1C A;  4KWD A;  3ZL6 A;  4NG6 A;  1YHM A;  3BNY A;  1DGP A;  5JV0 F;  4FJQ A;  1HM7 A;  2ZEV A;  3EZ3 A;  3KRA A;  5H9D A;  1WY0 A;  4MC8 A;  3N3L F;  5DJV F;  1HX9 A;  3BNX A;  3KRC B;  5IL8 A;  5EAS A;  3SAE A;  3Q1O A;  2E8U A;  2Z50 A;  2RAH A;  2Z4Y A;  5IKA A;  3WCL A;  3N1W F;  4JZB A;  3ACY A;  4E9Z A;  3NRI A;  4K10 A;  3N0G A;  5KSX F;  3WEJ A;  4LZ3 A;  1WMW A;  3Q2Q A;  3Q2Z A;  1RTR A;  4KVW A;  5ILJ A;  2F94 F;  4GAX A;  1VG3 A;  3WCE A;  1YYT A;  3P8R A;  5DGM F;  1ZW5 A;  4KK2 A; 
#chains in the Genus database with same CATH homology
 4LZ0 A;  2PS6 A;  3P5P A;  1WL0 A;  3ZMB A;  3ICK A;  4PVX F;  3WJN A;  2VF6 A;  3KRP A;  4H5E F;  5ER8 A;  2I19 A;  3LOM A;  5HN8 A;  3WCA A;  5DGN F;  5JUZ F;  4JXN A;  5E8K A;  3LK5 A;  3MAV A;  4P0W A;  1V4J A;  4NFJ F;  4LPH F;  3LG5 A;  5EAU A;  4KUX A;  3N6K F;  3G4D A;  1YYU A;  4F62 A;  3LDW A;  2ZEU A;  4DEM F;  4LUU A;  2ZY1 A;  5DHI A;  3WJK A;  4LLS A;  2E95 A;  5DGS F;  4JYX A;  3PDE A;  4GP2 A;  1YHK A;  5IMN A;  3RYW A;  5JV2 F;  3TFN A;  3M01 A;  2ONH A;  4OMH A;  5ILI A;  1EZF A;  3DYH A;  2PS5 A;  5EAT A;  5IK0 A;  4LFE A;  5C05 A;  4H5C F;  3NPK A;  4LOB A;  3WCM A;  3SDQ A;  3WCF A;  3WSB A;  3IPI A;  1N1Z A;  3Q30 A;  3LMD A;  4P0V A;  3N0F A;  1DI1 A;  2PS8 A;  1UBV A;  5DHK A;  3QQV A;  4F6V A;  3SDR A;  3NPR A;  1RQI A;  3N5J F;  2AEL A;  4JXY A;  4E1E A;  3MZV A;  1VG6 A;  2FTZ A;  2F8C F;  5IVG A;  3WEK A;  3KRA B;  1HXC A;  5B0K A;  2AZL A;  3LLW A;  3N5H F;  5DIQ F;  3ACX A;  2ZCQ A;  5B01 A;  4P0X A;  3KRO A;  4KKM A;  3OAB A;  3PKO A;  4GA3 A;  5B0J A;  3W7F A;  5B0I A;  4NFI F;  2F9K F;  4EA1 A;  2ZCO A;  1JFG A;  1PS1 A;  3WEF A;  5IMP A;  5HN9 A;  2F8Z F;  2ONG A;  5AYP A;  5IMI A;  5DJR F;  5JA0 F;  5B03 A;  2DH4 A;  4RYP A;  2Z78 A;  3ZMC A;  3M00 A;  5ERM A;  3WSA A;  4LFG A;  4DHD A;  3AE0 A;  3G4F A;  3VJE A;  1YYQ A;  3KRP B;  3PYB A;  3TC1 A;  2E92 A;  4GP1 A;  1RQJ A;  1VG2 A;  4KVI A;  3WCJ A;  2AEK A;  2AZK A;  3AQB B;  3VJB A;  3CKE A;  1WKZ A;  5ILH A;  4LZC A;  3KRF A;  4NKE A;  5AFX A;  5CG5 A;  2Q80 A;  2J1O A;  5IK9 A;  5ERO A;  1YQ7 A;  2E8V A;  3ICM A;  3ID0 A;  5A0J A;  1JFA A;  4ZQ8 A;  2J1P A;  4EA2 A;  4OGU A;  3WJO A;  3DYF A;  2F92 F;  4LFV F;  3N45 F;  5CG6 A;  2E90 A;  3QKC A;  3VJ9 A;  1V4I A;  2PS7 A;  3RYE A;  2E4O A;  3VJD A;  5A0K A;  3VJ8 A;  1HXG A;  3P8L A;  4N1Z F;  2Z4X A;  2FOR A;  3WC9 A;  1V4H A;  5B02 A;  4KPD A;  3TS7 A;  2F89 F;  3N49 F;  5B00 A;  3LGK A;  5ILY A;  5DJP F;  1WL1 A;  1YJ4 A;  1VG4 A;  4RNQ A;  5A0I A;  4DI5 A;  4MC3 A;  4KQS A;  1N23 A;  4JVJ F;  3WE9 A;  4Q23 A;  2OGD A;  5DZ2 A;  5JV1 F;  3M02 A;  3VJA A;  5AEL A;  4NKF A;  4OKM A;  4XQR F;  4DWG A;  2Q9Y A;  4KVY A;  2OPM A;  3CC9 A;  1KIZ A;  4JZX A;  4NFK F;  1V4K A;  4LXW A;  4KVD A;  3OAC A;  2Q58 A;  2Q9Z A;  2Z7H A;  5IM1 A;  3N3D A;  4PVY F;  3UCA A;  5IL3 A;  5ILK A;  3ADZ A;  3EFQ A;  4RXD A;  1YV5 A;  4LA5 A;  3WEI A;  3V1X A;  4DWB A;  2H8O A;  4KPJ A;  4FP4 A;  2Z52 A;  4NUA A;  1N21 A;  2EWG A;  4H5D F;  3ZCD A;  3KRC A;  3RMG A;  3LSN A;  3V66 A;  1UBW A;  3EGT A;  4MC0 A;  5ILD A;  3SDT A;  1N22 A;  1UBY A;  5B0M A;  3ACW A;  2OA6 A;  3N46 F;  3S9V A;  3DYG A;  5IKH A;  4OMG A;  3WCH A;  3LGZ B;  4HD1 A;  3CP6 A;  4LIX A;  5E8L A;  5HN7 A;  3P41 A;  3WCG A;  5I1U A;  2O1O A;  1YYS A;  1N1B A;  3B7L A;  3AQ0 A;  3OYR A;  4LTZ A;  1YYR A;  3APZ A;  5ILZ A;  3KRF B;  3M9U A;  4RXA A;  3ASX A;  3KB9 A;  3LVS A;  3PH7 A;  3V1V A;  2E94 A;  2Z4V A;  3LZ9 A;  3LEE A;  1YHL A;  3WCC A;  1FPS A;  4LPG F;  5HNA A;  4LA6 A;  1VG7 A;  4DXJ A;  5IN8 A;  2Z7I A;  2AET A;  3TFP A;  3WCD A;  2J5C A;  3KBK A;  1N24 A;  2QIS A;  4RXE A;  1HXA A;  3NF2 A;  3SDV A;  4QXS F;  4QPF A;  3VJC A;  1WL2 A;  2E8X A;  4F6X A;  2F7M F;  4KFA A;  4UMJ A;  3S4J A;  4XQT F;  1V4E A;  2AZJ A;  1KIY A;  4LLT A;  4L2X F;  1HM4 A;  5E8H A;  4LTV A;  3ZOU A;  4WK5 A;  4XQS F;  2Z4Z A;  2E93 A;  2PS4 A;  4E9U A;  1N20 A;  4OKZ A;  2E91 A;  3LJI A;  3WCB A;  3WEG A;  5ERN A;  3RBM A;  1WL3 A;  3WCI A;  3SDU A;  2OPN A;  3N1V F;  2E8W A;  5IK6 A;  2Z4W A;  4DZW A;  3ICN A;  5AHU B;  4KQU A;  3WEH A;  3AQC B;  2E8T A;  4EA0 A;  5DW7 A;  3PYA A;  3P5R A;  2ZCR A;  3M0G A;  2ZCS A;  3KRO B;  3OAC B;  3TFV A;  4RXC A;  3OAB B;  4N9U A;  1UBX A;  3IBA A;  4KQ5 A;  3ICZ A;  5B0L A;  2P1C A;  4KWD A;  3ZL6 A;  4NG6 A;  1YHM A;  3BNY A;  1DGP A;  5JV0 F;  4FJQ A;  1HM7 A;  2ZEV A;  3EZ3 A;  3KRA A;  5H9D A;  1WY0 A;  4MC8 A;  3N3L F;  5DJV F;  1HX9 A;  3BNX A;  3KRC B;  5IL8 A;  5EAS A;  3SAE A;  3Q1O A;  2E8U A;  2Z50 A;  2RAH A;  2Z4Y A;  5IKA A;  3WCL A;  3N1W F;  4JZB A;  3ACY A;  4E9Z A;  3NRI A;  4K10 A;  3N0G A;  5KSX F;  3WEJ A;  4LZ3 A;  1WMW A;  3Q2Q A;  3Q2Z A;  1RTR A;  4KVW A;  5ILJ A;  2F94 F;  4GAX A;  1VG3 A;  3WCE A;  1YYT A;  3P8R A;  5DGM F;  1ZW5 A;  4KK2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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