1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule keywords farnesyl pyrophosphate synthase
publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
source organism Trypanosoma cruzi
molecule tags Transferase
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
3TS7A 4GAXA 5IMPA 3P41A 1YQ7A 4Q23A 5DGNF 4FJQA 3SDVA 2OPNA 4P0XA 2PS6A 3WCHA 1UBYA 4OKMA 2E8UA 3LOMA 1HXCA 3KROB 1UBVA 2AZKA 2PS7A 4DHDA 1KIZA 4QPFA 4LA6A 2Q9YA 3LDWA 3QKCA 4KK2A 3VJ9A 2E90A 3WJOA 3WEGA 4DWGA 1RQIA 5DHIA 5AFXA 5DHKA 3CP6A 4KKMA 1JFAA 5HN9A 2I19A 3WCMA 3LK5A 4LXWA 3WCDA 1V4HA 1YYRA 5DJPF 4KUXA 2RAHA 1HM7A 5IK9A 2VF6A 5E8KA 3ASXA 4KPJA 3AE0A 1VG7A 4MC3A 1YJ4A 3N46F 4DWBA 3NPRA 4DEMF 3EZ3A 5EATA 1VG4A 4LOBA 2Q58A 3ZMCA 3PH7A 4UMJA 4GP2A 3CC9A 4PVXF 5JA0F 4KFAA 4GA3A 4JXYA 4EA1A 1VG2A 4LA5A 4KQUA 3OABA 3WJNA 3LGKA 4NFJF 3P8RA 5IKAA 3TFPA 1V4EA 3N3LF 3N49F 1HX9A 3OACA 4KPDA 3WEIA 3KRFB 5JV1F 5AYPA 2AELA 3ICMA 2ONHA 3TFVA 5ILJA 4RXDA 4F62A 5DGSF 3PYBA 1EZFA 5E8LA 3OABB 3LG5A 5EROA 3V66A 2AEKA 1WY0A 2Q80A 2F8ZF 3ZOUA 4LFEA 1YHKA 1ZW5A 2ZEVA 5ERMA 2E95A 2FTZA 5IK6A 3EFQA 5DW7A 4L2XF 4GP1A 4ZQ8A 1VG3A 5ER8A 5ERNA 3M01A 5B02A 3KBKA 3WSBA 3W7FA 3WCFA 4DZWA 3WC9A 5DGMF 3ZCDA 3VJEA 3DYFA 5IN8A 1N1ZA 3ACXA 1N23A 4JZBA 2OGDA 3N1VF 4LIXA 4N9UA 5EAUA 2E8VA 1WL3A 3S4JA 4NKFA 4RXCA 3CKEA 3LSNA 2E4OA 5B01A 3LLWA 5ILZA 2H8OA 3Q30A 3WCAA 5B0JA 2J1OA 4NG6A 2Z7HA 2FORA 3ID0A 3ACWA 3WEHA 3BNXA 2OA6A 3P5RA 3V1VA 4LTZA 4NKEA 5B0MA 3ICKA 5HN8A 2Z78A 4DXJA 3SDRA 3ACYA 3WCLA 4H5CF 5IMNA 5HNAA 3G4DA 3WEJA 2E8WA 3VJAA 2DH4A 2Z7IA 3BNYA 1HXGA 3SDTA 3OYRA 4LPHF 3WCCA 1DI1A 3N3DA 5ILDA 3IPIA 1RQJA 3KRPA 2PS5A 3P5PA 1WL0A 3M0GA 4FP4A 5DZ2A 4KQ5A 5B0IA 2O1OA 3Q2ZA 3P8LA 4LLSA 5IKHA 3ICZA 2F92F 5DJRF 3UCAA 3Q2QA 4KVWA 4LZ0A 4H5EF 3RYWA 4E9UA 5ILIA 5JV0F 1FPSA 3KRPB 2Z50A 2F9KF 2PS4A 1PS1A 3M00A 4LZ3A 5A0IA 3WCIA 1YYQA 2ZCSA 3LZ9A 3OACB 3RBMA 4NFKF 4H5DF 5H9DA 3PDEA 3WJKA 5AELA 4P0WA 3NF2A 2EWGA 1WL2A 1YV5A 4F6VA 2J1PA 5AHUB 3AQCB 3M9UA 1V4JA 4P0VA 4WK5A 1YYTA 2Z4VA 3Q1OA 4XQTF 3N5HF 5IM1A 4OGUA 3LMDA 2E93A 4LLTA 3TC1A 2ZCOA 5B00A 3ZMBA 3KROA 5ILHA 3WCEA 5B03A 4JVJF 2Z4ZA 2AZJA 5ILKA 2E94A 1UBWA 3M02A 3ZL6A 1N21A 2P1CA 4LPGF 3B7LA 3N1WF 5E8HA 3SDUA 3S9VA 2ZCQA 4XQRF 4LFGA 5IL8A 3RMGA 3PYAA 3ADZA 5CG6A 2Q9ZA 5EASA 3N0GA 3QQVA 1WKZA 4E9ZA 5B0LA 3KB9A 1UBXA 1YYUA 2F8CF 4PVYF 2ZEUA 1YHLA 5IK0A 1HM4A 5A0JA 2J5CA 4MC8A 3LEEA 4K10A 2Z4XA 4LTVA 4JXNA 2ZY1A 2OPMA 4JYXA 3DYHA 5IVGA 3KRAA 1JFGA 1WMWA 4NFIF 2F89F 2E91A 3SAEA 5DIQF 1N24A 4KQSA 3MZVA 3VJBA 3N5JF 2ONGA 5C05A 4DI5A 3IBAA 5A0KA 4LUUA 3MAVA 3RYEA 3WSAA 3EGTA 2E92A 1RTRA 4LZCA 4N1ZF 3NPKA 4OMHA 5DJVF 5JV2F 4OMGA 3LVSA 1V4IA 4EA0A 3KRAB 3KRFA 3AQ0A 4MC0A 2E8TA 3LGZB 5I1UA 2F94F 3WCGA 2PS8A 4RNQA 4RYPA 3TFNA 5ILYA 3WCBA 1V4KA 2QISA 3N45F 4LFVF 4EA2A 1VG6A 5IMIA 3WEFA 4HD1A 2Z4YA 2AETA 3ICNA 1YYSA 3KRCA 1N1BA 3G4FA 3LJIA 3SDQA 3VJ8A 1N20A 2Z52A 3APZA 3N6KF 1N22A 2E8XA 3WE9A 3AQBB 3V1XA 4F6XA 2Z4WA 2ZCRA 4OKZA 1KIYA 4E1EA 5B0KA 4RXEA 1DGPA 4KVYA 5CG5A 5KSXF 2F7MF 5JUZF 3KRCB 3PKOA 4RXAA 3NRIA 4QXSF 4NUAA 4XQSF 2AZLA 3VJDA 4KVIA 1YHMA 3WCJA 3N0FA 3DYGA 1WL1A 5HN7A 4JZXA 1HXAA 5IL3A 4KWDA 3VJCA 3WEKA 4KVDA
chains in the Genus database with same CATH superfamily
3TS7A 4GAXA 5IMPA 3P41A 1YQ7A 4Q23A 5DGNF 4FJQA 3SDVA 2OPNA 4P0XA 2PS6A 3WCHA 1UBYA 4OKMA 2E8UA 3LOMA 1HXCA 3KROB 1UBVA 2AZKA 2PS7A 4DHDA 1KIZA 4QPFA 4LA6A 2Q9YA 3LDWA 3QKCA 4KK2A 3VJ9A 2E90A 3WJOA 3WEGA 4DWGA 1RQIA 5DHIA 5AFXA 5DHKA 3CP6A 4KKMA 1JFAA 5HN9A 2I19A 3WCMA 3LK5A 4LXWA 3WCDA 1V4HA 1YYRA 5DJPF 4KUXA 2RAHA 1HM7A 5IK9A 2VF6A 5E8KA 3ASXA 4KPJA 3AE0A 1VG7A 4MC3A 1YJ4A 3N46F 4DWBA 3NPRA 4DEMF 3EZ3A 5EATA 1VG4A 4LOBA 2Q58A 3ZMCA 3PH7A 4UMJA 4GP2A 3CC9A 4PVXF 5JA0F 4KFAA 4GA3A 4JXYA 4EA1A 1VG2A 4LA5A 4KQUA 3OABA 3WJNA 3LGKA 4NFJF 3P8RA 5IKAA 3TFPA 1V4EA 3N3LF 3N49F 1HX9A 3OACA 4KPDA 3WEIA 3KRFB 5JV1F 5AYPA 2AELA 3ICMA 2ONHA 3TFVA 5ILJA 4RXDA 4F62A 5DGSF 3PYBA 1EZFA 5E8LA 3OABB 3LG5A 5EROA 3V66A 2AEKA 1WY0A 2Q80A 2F8ZF 3ZOUA 4LFEA 1YHKA 1ZW5A 2ZEVA 5ERMA 2E95A 2FTZA 5IK6A 3EFQA 5DW7A 4L2XF 4GP1A 4ZQ8A 1VG3A 5ER8A 5ERNA 3M01A 5B02A 3KBKA 3WSBA 3W7FA 3WCFA 4DZWA 3WC9A 5DGMF 3ZCDA 3VJEA 3DYFA 5IN8A 1N1ZA 3ACXA 1N23A 4JZBA 2OGDA 3N1VF 4LIXA 4N9UA 5EAUA 2E8VA 1WL3A 3S4JA 4NKFA 4RXCA 3CKEA 3LSNA 2E4OA 5B01A 3LLWA 5ILZA 2H8OA 3Q30A 3WCAA 5B0JA 2J1OA 4NG6A 2Z7HA 2FORA 3ID0A 3ACWA 3WEHA 3BNXA 2OA6A 3P5RA 3V1VA 4LTZA 4NKEA 5B0MA 3ICKA 5HN8A 2Z78A 4DXJA 3SDRA 3ACYA 3WCLA 4H5CF 5IMNA 5HNAA 3G4DA 3WEJA 2E8WA 3VJAA 2DH4A 2Z7IA 3BNYA 1HXGA 3SDTA 3OYRA 4LPHF 3WCCA 1DI1A 3N3DA 5ILDA 3IPIA 1RQJA 3KRPA 2PS5A 3P5PA 1WL0A 3M0GA 4FP4A 5DZ2A 4KQ5A 5B0IA 2O1OA 3Q2ZA 3P8LA 4LLSA 5IKHA 3ICZA 2F92F 5DJRF 3UCAA 3Q2QA 4KVWA 4LZ0A 4H5EF 3RYWA 4E9UA 5ILIA 5JV0F 1FPSA 3KRPB 2Z50A 2F9KF 2PS4A 1PS1A 3M00A 4LZ3A 5A0IA 3WCIA 1YYQA 2ZCSA 3LZ9A 3OACB 3RBMA 4NFKF 4H5DF 5H9DA 3PDEA 3WJKA 5AELA 4P0WA 3NF2A 2EWGA 1WL2A 1YV5A 4F6VA 2J1PA 5AHUB 3AQCB 3M9UA 1V4JA 4P0VA 4WK5A 1YYTA 2Z4VA 3Q1OA 4XQTF 3N5HF 5IM1A 4OGUA 3LMDA 2E93A 4LLTA 3TC1A 2ZCOA 5B00A 3ZMBA 3KROA 5ILHA 3WCEA 5B03A 4JVJF 2Z4ZA 2AZJA 5ILKA 2E94A 1UBWA 3M02A 3ZL6A 1N21A 2P1CA 4LPGF 3B7LA 3N1WF 5E8HA 3SDUA 3S9VA 2ZCQA 4XQRF 4LFGA 5IL8A 3RMGA 3PYAA 3ADZA 5CG6A 2Q9ZA 5EASA 3N0GA 3QQVA 1WKZA 4E9ZA 5B0LA 3KB9A 1UBXA 1YYUA 2F8CF 4PVYF 2ZEUA 1YHLA 5IK0A 1HM4A 5A0JA 2J5CA 4MC8A 3LEEA 4K10A 2Z4XA 4LTVA 4JXNA 2ZY1A 2OPMA 4JYXA 3DYHA 5IVGA 3KRAA 1JFGA 1WMWA 4NFIF 2F89F 2E91A 3SAEA 5DIQF 1N24A 4KQSA 3MZVA 3VJBA 3N5JF 2ONGA 5C05A 4DI5A 3IBAA 5A0KA 4LUUA 3MAVA 3RYEA 3WSAA 3EGTA 2E92A 1RTRA 4LZCA 4N1ZF 3NPKA 4OMHA 5DJVF 5JV2F 4OMGA 3LVSA 1V4IA 4EA0A 3KRAB 3KRFA 3AQ0A 4MC0A 2E8TA 3LGZB 5I1UA 2F94F 3WCGA 2PS8A 4RNQA 4RYPA 3TFNA 5ILYA 3WCBA 1V4KA 2QISA 3N45F 4LFVF 4EA2A 1VG6A 5IMIA 3WEFA 4HD1A 2Z4YA 2AETA 3ICNA 1YYSA 3KRCA 1N1BA 3G4FA 3LJIA 3SDQA 3VJ8A 1N20A 2Z52A 3APZA 3N6KF 1N22A 2E8XA 3WE9A 3AQBB 3V1XA 4F6XA 2Z4WA 2ZCRA 4OKZA 1KIYA 4E1EA 5B0KA 4RXEA 1DGPA 4KVYA 5CG5A 5KSXF 2F7MF 5JUZF 3KRCB 3PKOA 4RXAA 3NRIA 4QXSF 4NUAA 4XQSF 2AZLA 3VJDA 4KVIA 1YHMA 3WCJA 3N0FA 3DYGA 1WL1A 5HN7A 4JZXA 1HXAA 5IL3A 4KWDA 3VJCA 3WEKA 4KVDA
chains in the Genus database with same CATH topology
3TS7A 4GAXA 5IMPA 3P41A 1YQ7A 4Q23A 5DGNF 4FJQA 3SDVA 2OPNA 4P0XA 2PS6A 3WCHA 1UBYA 4OKMA 2E8UA 3LOMA 1HXCA 3KROB 1UBVA 2AZKA 2PS7A 4DHDA 1KIZA 4QPFA 4LA6A 2Q9YA 3LDWA 3QKCA 4KK2A 3VJ9A 2E90A 3WJOA 3WEGA 4DWGA 1RQIA 5DHIA 5AFXA 5DHKA 3CP6A 4KKMA 1JFAA 5HN9A 2I19A 3WCMA 3LK5A 4LXWA 3WCDA 1V4HA 1YYRA 5DJPF 4KUXA 2RAHA 1HM7A 5IK9A 2VF6A 5E8KA 3ASXA 4KPJA 3AE0A 1VG7A 4MC3A 1YJ4A 3N46F 4DWBA 3NPRA 4DEMF 3EZ3A 5EATA 1VG4A 4LOBA 2Q58A 3ZMCA 3PH7A 4UMJA 4GP2A 3CC9A 4PVXF 5JA0F 4KFAA 4GA3A 4JXYA 4EA1A 1VG2A 4LA5A 4KQUA 3OABA 3WJNA 3LGKA 4NFJF 3P8RA 5IKAA 3TFPA 1V4EA 3N3LF 3N49F 1HX9A 3OACA 4KPDA 3WEIA 3KRFB 5JV1F 5AYPA 2AELA 3ICMA 2ONHA 3TFVA 5ILJA 4RXDA 4F62A 5DGSF 3PYBA 1EZFA 5E8LA 3OABB 3LG5A 5EROA 3V66A 2AEKA 1WY0A 2Q80A 2F8ZF 3ZOUA 4LFEA 1YHKA 1ZW5A 2ZEVA 5ERMA 2E95A 2FTZA 5IK6A 3EFQA 5DW7A 4L2XF 4GP1A 4ZQ8A 1VG3A 5ER8A 5ERNA 3M01A 5B02A 3KBKA 3WSBA 3W7FA 3WCFA 4DZWA 3WC9A 5DGMF 3ZCDA 3VJEA 3DYFA 5IN8A 1N1ZA 3ACXA 1N23A 4JZBA 2OGDA 3N1VF 4LIXA 4N9UA 5EAUA 2E8VA 1WL3A 3S4JA 4NKFA 4RXCA 3CKEA 3LSNA 2E4OA 5B01A 3LLWA 5ILZA 2H8OA 3Q30A 3WCAA 5B0JA 2J1OA 4NG6A 2Z7HA 2FORA 3ID0A 3ACWA 3WEHA 3BNXA 2OA6A 3P5RA 3V1VA 4LTZA 4NKEA 5B0MA 3ICKA 5HN8A 2Z78A 4DXJA 3SDRA 3ACYA 3WCLA 4H5CF 5IMNA 5HNAA 3G4DA 3WEJA 2E8WA 3VJAA 2DH4A 2Z7IA 3BNYA 1HXGA 3SDTA 3OYRA 4LPHF 3WCCA 1DI1A 3N3DA 5ILDA 3IPIA 1RQJA 3KRPA 2PS5A 3P5PA 1WL0A 3M0GA 4FP4A 5DZ2A 4KQ5A 5B0IA 2O1OA 3Q2ZA 3P8LA 4LLSA 5IKHA 3ICZA 2F92F 5DJRF 3UCAA 3Q2QA 4KVWA 4LZ0A 4H5EF 3RYWA 4E9UA 5ILIA 5JV0F 1FPSA 3KRPB 2Z50A 2F9KF 2PS4A 1PS1A 3M00A 4LZ3A 5A0IA 3WCIA 1YYQA 2ZCSA 3LZ9A 3OACB 3RBMA 4NFKF 4H5DF 5H9DA 3PDEA 3WJKA 5AELA 4P0WA 3NF2A 2EWGA 1WL2A 1YV5A 4F6VA 2J1PA 5AHUB 3AQCB 3M9UA 1V4JA 4P0VA 4WK5A 1YYTA 2Z4VA 3Q1OA 4XQTF 3N5HF 5IM1A 4OGUA 3LMDA 2E93A 4LLTA 3TC1A 2ZCOA 5B00A 3ZMBA 3KROA 5ILHA 3WCEA 5B03A 4JVJF 2Z4ZA 2AZJA 5ILKA 2E94A 1UBWA 3M02A 3ZL6A 1N21A 2P1CA 4LPGF 3B7LA 3N1WF 5E8HA 3SDUA 3S9VA 2ZCQA 4XQRF 4LFGA 5IL8A 3RMGA 3PYAA 3ADZA 5CG6A 2Q9ZA 5EASA 3N0GA 3QQVA 1WKZA 4E9ZA 5B0LA 3KB9A 1UBXA 1YYUA 2F8CF 4PVYF 2ZEUA 1YHLA 5IK0A 1HM4A 5A0JA 2J5CA 4MC8A 3LEEA 4K10A 2Z4XA 4LTVA 4JXNA 2ZY1A 2OPMA 4JYXA 3DYHA 5IVGA 3KRAA 1JFGA 1WMWA 4NFIF 2F89F 2E91A 3SAEA 5DIQF 1N24A 4KQSA 3MZVA 3VJBA 3N5JF 2ONGA 5C05A 4DI5A 3IBAA 5A0KA 4LUUA 3MAVA 3RYEA 3WSAA 3EGTA 2E92A 1RTRA 4LZCA 4N1ZF 3NPKA 4OMHA 5DJVF 5JV2F 4OMGA 3LVSA 1V4IA 4EA0A 3KRAB 3KRFA 3AQ0A 4MC0A 2E8TA 3LGZB 5I1UA 2F94F 3WCGA 2PS8A 4RNQA 4RYPA 3TFNA 5ILYA 3WCBA 1V4KA 2QISA 3N45F 4LFVF 4EA2A 1VG6A 5IMIA 3WEFA 4HD1A 2Z4YA 2AETA 3ICNA 1YYSA 3KRCA 1N1BA 3G4FA 3LJIA 3SDQA 3VJ8A 1N20A 2Z52A 3APZA 3N6KF 1N22A 2E8XA 3WE9A 3AQBB 3V1XA 4F6XA 2Z4WA 2ZCRA 4OKZA 1KIYA 4E1EA 5B0KA 4RXEA 1DGPA 4KVYA 5CG5A 5KSXF 2F7MF 5JUZF 3KRCB 3PKOA 4RXAA 3NRIA 4QXSF 4NUAA 4XQSF 2AZLA 3VJDA 4KVIA 1YHMA 3WCJA 3N0FA 3DYGA 1WL1A 5HN7A 4JZXA 1HXAA 5IL3A 4KWDA 3VJCA 3WEKA 4KVDA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3TS7 A;  4GAX A;  5IMP A;  3P41 A;  1YQ7 A;  4Q23 A;  5DGN F;  4FJQ A;  3SDV A;  2OPN A;  4P0X A;  2PS6 A;  3WCH A;  1UBY A;  4OKM A;  2E8U A;  3LOM A;  1HXC A;  3KRO B;  1UBV A;  2AZK A;  2PS7 A;  4DHD A;  1KIZ A;  4QPF A;  4LA6 A;  2Q9Y A;  3LDW A;  3QKC A;  4KK2 A;  3VJ9 A;  2E90 A;  3WJO A;  3WEG A;  4DWG A;  1RQI A;  5DHI A;  5AFX A;  5DHK A;  3CP6 A;  4KKM A;  1JFA A;  5HN9 A;  2I19 A;  3WCM A;  3LK5 A;  4LXW A;  3WCD A;  1V4H A;  1YYR A;  5DJP F;  4KUX A;  2RAH A;  1HM7 A;  5IK9 A;  2VF6 A;  5E8K A;  3ASX A;  4KPJ A;  3AE0 A;  1VG7 A;  4MC3 A;  1YJ4 A;  3N46 F;  4DWB A;  3NPR A;  4DEM F;  3EZ3 A;  5EAT A;  1VG4 A;  4LOB A;  2Q58 A;  3ZMC A;  3PH7 A;  4UMJ A;  4GP2 A;  3CC9 A;  4PVX F;  5JA0 F;  4KFA A;  4GA3 A;  4JXY A;  4EA1 A;  1VG2 A;  4LA5 A;  4KQU A;  3OAB A;  3WJN A;  3LGK A;  4NFJ F;  3P8R A;  5IKA A;  3TFP A;  1V4E A;  3N3L F;  3N49 F;  1HX9 A;  3OAC A;  4KPD A;  3WEI A;  3KRF B;  5JV1 F;  5AYP A;  2AEL A;  3ICM A;  2ONH A;  3TFV A;  5ILJ A;  4RXD A;  4F62 A;  5DGS F;  3PYB A;  1EZF A;  5E8L A;  3OAB B;  3LG5 A;  5ERO A;  3V66 A;  2AEK A;  1WY0 A;  2Q80 A;  2F8Z F;  3ZOU A;  4LFE A;  1YHK A;  1ZW5 A;  2ZEV A;  5ERM A;  2E95 A;  2FTZ A;  5IK6 A;  3EFQ A;  5DW7 A;  4L2X F;  4GP1 A;  4ZQ8 A;  1VG3 A;  5ER8 A;  5ERN A;  3M01 A;  5B02 A;  3KBK A;  3WSB A;  3W7F A;  3WCF A;  4DZW A;  3WC9 A;  5DGM F;  3ZCD A;  3VJE A;  3DYF A;  5IN8 A;  1N1Z A;  3ACX A;  1N23 A;  4JZB A;  2OGD A;  3N1V F;  4LIX A;  4N9U A;  5EAU A;  2E8V A;  1WL3 A;  3S4J A;  4NKF A;  4RXC A;  3CKE A;  3LSN A;  2E4O A;  5B01 A;  3LLW A;  5ILZ A;  2H8O A;  3Q30 A;  3WCA A;  5B0J A;  2J1O A;  4NG6 A;  2Z7H A;  2FOR A;  3ID0 A;  3ACW A;  3WEH A;  3BNX A;  2OA6 A;  3P5R A;  3V1V A;  4LTZ A;  4NKE A;  5B0M A;  3ICK A;  5HN8 A;  2Z78 A;  4DXJ A;  3SDR A;  3ACY A;  3WCL A;  4H5C F;  5IMN A;  5HNA A;  3G4D A;  3WEJ A;  2E8W A;  3VJA A;  2DH4 A;  2Z7I A;  3BNY A;  1HXG A;  3SDT A;  3OYR A;  4LPH F;  3WCC A;  1DI1 A;  3N3D A;  5ILD A;  3IPI A;  1RQJ A;  3KRP A;  2PS5 A;  3P5P A;  1WL0 A;  3M0G A;  4FP4 A;  5DZ2 A;  4KQ5 A;  5B0I A;  2O1O A;  3Q2Z A;  3P8L A;  4LLS A;  5IKH A;  3ICZ A;  2F92 F;  5DJR F;  3UCA A;  3Q2Q A;  4KVW A;  4LZ0 A;  4H5E F;  3RYW A;  4E9U A;  5ILI A;  5JV0 F;  1FPS A;  3KRP B;  2Z50 A;  2F9K F;  2PS4 A;  1PS1 A;  3M00 A;  4LZ3 A;  5A0I A;  3WCI A;  1YYQ A;  2ZCS A;  3LZ9 A;  3OAC B;  3RBM A;  4NFK F;  4H5D F;  5H9D A;  3PDE A;  3WJK A;  5AEL A;  4P0W A;  3NF2 A;  2EWG A;  1WL2 A;  1YV5 A;  4F6V A;  2J1P A;  5AHU B;  3AQC B;  3M9U A;  1V4J A;  4P0V A;  4WK5 A;  1YYT A;  2Z4V A;  3Q1O A;  4XQT F;  3N5H F;  5IM1 A;  4OGU A;  3LMD A;  2E93 A;  4LLT A;  3TC1 A;  2ZCO A;  5B00 A;  3ZMB A;  3KRO A;  5ILH A;  3WCE A;  5B03 A;  4JVJ F;  2Z4Z A;  2AZJ A;  5ILK A;  2E94 A;  1UBW A;  3M02 A;  3ZL6 A;  1N21 A;  2P1C A;  4LPG F;  3B7L A;  3N1W F;  5E8H A;  3SDU A;  3S9V A;  2ZCQ A;  4XQR F;  4LFG A;  5IL8 A;  3RMG A;  3PYA A;  3ADZ A;  5CG6 A;  2Q9Z A;  5EAS A;  3N0G A;  3QQV A;  1WKZ A;  4E9Z A;  5B0L A;  3KB9 A;  1UBX A;  1YYU A;  2F8C F;  4PVY F;  2ZEU A;  1YHL A;  5IK0 A;  1HM4 A;  5A0J A;  2J5C A;  4MC8 A;  3LEE A;  4K10 A;  2Z4X A;  4LTV A;  4JXN A;  2ZY1 A;  2OPM A;  4JYX A;  3DYH A;  5IVG A;  3KRA A;  1JFG A;  1WMW A;  4NFI F;  2F89 F;  2E91 A;  3SAE A;  5DIQ F;  1N24 A;  4KQS A;  3MZV A;  3VJB A;  3N5J F;  2ONG A;  5C05 A;  4DI5 A;  3IBA A;  5A0K A;  4LUU A;  3MAV A;  3RYE A;  3WSA A;  3EGT A;  2E92 A;  1RTR A;  4LZC A;  4N1Z F;  3NPK A;  4OMH A;  5DJV F;  5JV2 F;  4OMG A;  3LVS A;  1V4I A;  4EA0 A;  3KRA B;  3KRF A;  3AQ0 A;  4MC0 A;  2E8T A;  3LGZ B;  5I1U A;  2F94 F;  3WCG A;  2PS8 A;  4RNQ A;  4RYP A;  3TFN A;  5ILY A;  3WCB A;  1V4K A;  2QIS A;  3N45 F;  4LFV F;  4EA2 A;  1VG6 A;  5IMI A;  3WEF A;  4HD1 A;  2Z4Y A;  2AET A;  3ICN A;  1YYS A;  3KRC A;  1N1B A;  3G4F A;  3LJI A;  3SDQ A;  3VJ8 A;  1N20 A;  2Z52 A;  3APZ A;  3N6K F;  1N22 A;  2E8X A;  3WE9 A;  3AQB B;  3V1X A;  4F6X A;  2Z4W A;  2ZCR A;  4OKZ A;  1KIY A;  4E1E A;  5B0K A;  4RXE A;  1DGP A;  4KVY A;  5CG5 A;  5KSX F;  2F7M F;  5JUZ F;  3KRC B;  3PKO A;  4RXA A;  3NRI A;  4QXS F;  4NUA A;  4XQS F;  2AZL A;  3VJD A;  4KVI A;  1YHM A;  3WCJ A;  3N0F A;  3DYG A;  1WL1 A;  5HN7 A;  4JZX A;  1HXA A;  5IL3 A;  4KWD A;  3VJC A;  3WEK A;  4KVD A; 
#chains in the Genus database with same CATH topology
 3TS7 A;  4GAX A;  5IMP A;  3P41 A;  1YQ7 A;  4Q23 A;  5DGN F;  4FJQ A;  3SDV A;  2OPN A;  4P0X A;  2PS6 A;  3WCH A;  1UBY A;  4OKM A;  2E8U A;  3LOM A;  1HXC A;  3KRO B;  1UBV A;  2AZK A;  2PS7 A;  4DHD A;  1KIZ A;  4QPF A;  4LA6 A;  2Q9Y A;  3LDW A;  3QKC A;  4KK2 A;  3VJ9 A;  2E90 A;  3WJO A;  3WEG A;  4DWG A;  1RQI A;  5DHI A;  5AFX A;  5DHK A;  3CP6 A;  4KKM A;  1JFA A;  5HN9 A;  2I19 A;  3WCM A;  3LK5 A;  4LXW A;  3WCD A;  1V4H A;  1YYR A;  5DJP F;  4KUX A;  2RAH A;  1HM7 A;  5IK9 A;  2VF6 A;  5E8K A;  3ASX A;  4KPJ A;  3AE0 A;  1VG7 A;  4MC3 A;  1YJ4 A;  3N46 F;  4DWB A;  3NPR A;  4DEM F;  3EZ3 A;  5EAT A;  1VG4 A;  4LOB A;  2Q58 A;  3ZMC A;  3PH7 A;  4UMJ A;  4GP2 A;  3CC9 A;  4PVX F;  5JA0 F;  4KFA A;  4GA3 A;  4JXY A;  4EA1 A;  1VG2 A;  4LA5 A;  4KQU A;  3OAB A;  3WJN A;  3LGK A;  4NFJ F;  3P8R A;  5IKA A;  3TFP A;  1V4E A;  3N3L F;  3N49 F;  1HX9 A;  3OAC A;  4KPD A;  3WEI A;  3KRF B;  5JV1 F;  5AYP A;  2AEL A;  3ICM A;  2ONH A;  3TFV A;  5ILJ A;  4RXD A;  4F62 A;  5DGS F;  3PYB A;  1EZF A;  5E8L A;  3OAB B;  3LG5 A;  5ERO A;  3V66 A;  2AEK A;  1WY0 A;  2Q80 A;  2F8Z F;  3ZOU A;  4LFE A;  1YHK A;  1ZW5 A;  2ZEV A;  5ERM A;  2E95 A;  2FTZ A;  5IK6 A;  3EFQ A;  5DW7 A;  4L2X F;  4GP1 A;  4ZQ8 A;  1VG3 A;  5ER8 A;  5ERN A;  3M01 A;  5B02 A;  3KBK A;  3WSB A;  3W7F A;  3WCF A;  4DZW A;  3WC9 A;  5DGM F;  3ZCD A;  3VJE A;  3DYF A;  5IN8 A;  1N1Z A;  3ACX A;  1N23 A;  4JZB A;  2OGD A;  3N1V F;  4LIX A;  4N9U A;  5EAU A;  2E8V A;  1WL3 A;  3S4J A;  4NKF A;  4RXC A;  3CKE A;  3LSN A;  2E4O A;  5B01 A;  3LLW A;  5ILZ A;  2H8O A;  3Q30 A;  3WCA A;  5B0J A;  2J1O A;  4NG6 A;  2Z7H A;  2FOR A;  3ID0 A;  3ACW A;  3WEH A;  3BNX A;  2OA6 A;  3P5R A;  3V1V A;  4LTZ A;  4NKE A;  5B0M A;  3ICK A;  5HN8 A;  2Z78 A;  4DXJ A;  3SDR A;  3ACY A;  3WCL A;  4H5C F;  5IMN A;  5HNA A;  3G4D A;  3WEJ A;  2E8W A;  3VJA A;  2DH4 A;  2Z7I A;  3BNY A;  1HXG A;  3SDT A;  3OYR A;  4LPH F;  3WCC A;  1DI1 A;  3N3D A;  5ILD A;  3IPI A;  1RQJ A;  3KRP A;  2PS5 A;  3P5P A;  1WL0 A;  3M0G A;  4FP4 A;  5DZ2 A;  4KQ5 A;  5B0I A;  2O1O A;  3Q2Z A;  3P8L A;  4LLS A;  5IKH A;  3ICZ A;  2F92 F;  5DJR F;  3UCA A;  3Q2Q A;  4KVW A;  4LZ0 A;  4H5E F;  3RYW A;  4E9U A;  5ILI A;  5JV0 F;  1FPS A;  3KRP B;  2Z50 A;  2F9K F;  2PS4 A;  1PS1 A;  3M00 A;  4LZ3 A;  5A0I A;  3WCI A;  1YYQ A;  2ZCS A;  3LZ9 A;  3OAC B;  3RBM A;  4NFK F;  4H5D F;  5H9D A;  3PDE A;  3WJK A;  5AEL A;  4P0W A;  3NF2 A;  2EWG A;  1WL2 A;  1YV5 A;  4F6V A;  2J1P A;  5AHU B;  3AQC B;  3M9U A;  1V4J A;  4P0V A;  4WK5 A;  1YYT A;  2Z4V A;  3Q1O A;  4XQT F;  3N5H F;  5IM1 A;  4OGU A;  3LMD A;  2E93 A;  4LLT A;  3TC1 A;  2ZCO A;  5B00 A;  3ZMB A;  3KRO A;  5ILH A;  3WCE A;  5B03 A;  4JVJ F;  2Z4Z A;  2AZJ A;  5ILK A;  2E94 A;  1UBW A;  3M02 A;  3ZL6 A;  1N21 A;  2P1C A;  4LPG F;  3B7L A;  3N1W F;  5E8H A;  3SDU A;  3S9V A;  2ZCQ A;  4XQR F;  4LFG A;  5IL8 A;  3RMG A;  3PYA A;  3ADZ A;  5CG6 A;  2Q9Z A;  5EAS A;  3N0G A;  3QQV A;  1WKZ A;  4E9Z A;  5B0L A;  3KB9 A;  1UBX A;  1YYU A;  2F8C F;  4PVY F;  2ZEU A;  1YHL A;  5IK0 A;  1HM4 A;  5A0J A;  2J5C A;  4MC8 A;  3LEE A;  4K10 A;  2Z4X A;  4LTV A;  4JXN A;  2ZY1 A;  2OPM A;  4JYX A;  3DYH A;  5IVG A;  3KRA A;  1JFG A;  1WMW A;  4NFI F;  2F89 F;  2E91 A;  3SAE A;  5DIQ F;  1N24 A;  4KQS A;  3MZV A;  3VJB A;  3N5J F;  2ONG A;  5C05 A;  4DI5 A;  3IBA A;  5A0K A;  4LUU A;  3MAV A;  3RYE A;  3WSA A;  3EGT A;  2E92 A;  1RTR A;  4LZC A;  4N1Z F;  3NPK A;  4OMH A;  5DJV F;  5JV2 F;  4OMG A;  3LVS A;  1V4I A;  4EA0 A;  3KRA B;  3KRF A;  3AQ0 A;  4MC0 A;  2E8T A;  3LGZ B;  5I1U A;  2F94 F;  3WCG A;  2PS8 A;  4RNQ A;  4RYP A;  3TFN A;  5ILY A;  3WCB A;  1V4K A;  2QIS A;  3N45 F;  4LFV F;  4EA2 A;  1VG6 A;  5IMI A;  3WEF A;  4HD1 A;  2Z4Y A;  2AET A;  3ICN A;  1YYS A;  3KRC A;  1N1B A;  3G4F A;  3LJI A;  3SDQ A;  3VJ8 A;  1N20 A;  2Z52 A;  3APZ A;  3N6K F;  1N22 A;  2E8X A;  3WE9 A;  3AQB B;  3V1X A;  4F6X A;  2Z4W A;  2ZCR A;  4OKZ A;  1KIY A;  4E1E A;  5B0K A;  4RXE A;  1DGP A;  4KVY A;  5CG5 A;  5KSX F;  2F7M F;  5JUZ F;  3KRC B;  3PKO A;  4RXA A;  3NRI A;  4QXS F;  4NUA A;  4XQS F;  2AZL A;  3VJD A;  4KVI A;  1YHM A;  3WCJ A;  3N0F A;  3DYG A;  1WL1 A;  5HN7 A;  4JZX A;  1HXA A;  5IL3 A;  4KWD A;  3VJC A;  3WEK A;  4KVD A; 
#chains in the Genus database with same CATH homology
 3TS7 A;  4GAX A;  5IMP A;  3P41 A;  1YQ7 A;  4Q23 A;  5DGN F;  4FJQ A;  3SDV A;  2OPN A;  4P0X A;  2PS6 A;  3WCH A;  1UBY A;  4OKM A;  2E8U A;  3LOM A;  1HXC A;  3KRO B;  1UBV A;  2AZK A;  2PS7 A;  4DHD A;  1KIZ A;  4QPF A;  4LA6 A;  2Q9Y A;  3LDW A;  3QKC A;  4KK2 A;  3VJ9 A;  2E90 A;  3WJO A;  3WEG A;  4DWG A;  1RQI A;  5DHI A;  5AFX A;  5DHK A;  3CP6 A;  4KKM A;  1JFA A;  5HN9 A;  2I19 A;  3WCM A;  3LK5 A;  4LXW A;  3WCD A;  1V4H A;  1YYR A;  5DJP F;  4KUX A;  2RAH A;  1HM7 A;  5IK9 A;  2VF6 A;  5E8K A;  3ASX A;  4KPJ A;  3AE0 A;  1VG7 A;  4MC3 A;  1YJ4 A;  3N46 F;  4DWB A;  3NPR A;  4DEM F;  3EZ3 A;  5EAT A;  1VG4 A;  4LOB A;  2Q58 A;  3ZMC A;  3PH7 A;  4UMJ A;  4GP2 A;  3CC9 A;  4PVX F;  5JA0 F;  4KFA A;  4GA3 A;  4JXY A;  4EA1 A;  1VG2 A;  4LA5 A;  4KQU A;  3OAB A;  3WJN A;  3LGK A;  4NFJ F;  3P8R A;  5IKA A;  3TFP A;  1V4E A;  3N3L F;  3N49 F;  1HX9 A;  3OAC A;  4KPD A;  3WEI A;  3KRF B;  5JV1 F;  5AYP A;  2AEL A;  3ICM A;  2ONH A;  3TFV A;  5ILJ A;  4RXD A;  4F62 A;  5DGS F;  3PYB A;  1EZF A;  5E8L A;  3OAB B;  3LG5 A;  5ERO A;  3V66 A;  2AEK A;  1WY0 A;  2Q80 A;  2F8Z F;  3ZOU A;  4LFE A;  1YHK A;  1ZW5 A;  2ZEV A;  5ERM A;  2E95 A;  2FTZ A;  5IK6 A;  3EFQ A;  5DW7 A;  4L2X F;  4GP1 A;  4ZQ8 A;  1VG3 A;  5ER8 A;  5ERN A;  3M01 A;  5B02 A;  3KBK A;  3WSB A;  3W7F A;  3WCF A;  4DZW A;  3WC9 A;  5DGM F;  3ZCD A;  3VJE A;  3DYF A;  5IN8 A;  1N1Z A;  3ACX A;  1N23 A;  4JZB A;  2OGD A;  3N1V F;  4LIX A;  4N9U A;  5EAU A;  2E8V A;  1WL3 A;  3S4J A;  4NKF A;  4RXC A;  3CKE A;  3LSN A;  2E4O A;  5B01 A;  3LLW A;  5ILZ A;  2H8O A;  3Q30 A;  3WCA A;  5B0J A;  2J1O A;  4NG6 A;  2Z7H A;  2FOR A;  3ID0 A;  3ACW A;  3WEH A;  3BNX A;  2OA6 A;  3P5R A;  3V1V A;  4LTZ A;  4NKE A;  5B0M A;  3ICK A;  5HN8 A;  2Z78 A;  4DXJ A;  3SDR A;  3ACY A;  3WCL A;  4H5C F;  5IMN A;  5HNA A;  3G4D A;  3WEJ A;  2E8W A;  3VJA A;  2DH4 A;  2Z7I A;  3BNY A;  1HXG A;  3SDT A;  3OYR A;  4LPH F;  3WCC A;  1DI1 A;  3N3D A;  5ILD A;  3IPI A;  1RQJ A;  3KRP A;  2PS5 A;  3P5P A;  1WL0 A;  3M0G A;  4FP4 A;  5DZ2 A;  4KQ5 A;  5B0I A;  2O1O A;  3Q2Z A;  3P8L A;  4LLS A;  5IKH A;  3ICZ A;  2F92 F;  5DJR F;  3UCA A;  3Q2Q A;  4KVW A;  4LZ0 A;  4H5E F;  3RYW A;  4E9U A;  5ILI A;  5JV0 F;  1FPS A;  3KRP B;  2Z50 A;  2F9K F;  2PS4 A;  1PS1 A;  3M00 A;  4LZ3 A;  5A0I A;  3WCI A;  1YYQ A;  2ZCS A;  3LZ9 A;  3OAC B;  3RBM A;  4NFK F;  4H5D F;  5H9D A;  3PDE A;  3WJK A;  5AEL A;  4P0W A;  3NF2 A;  2EWG A;  1WL2 A;  1YV5 A;  4F6V A;  2J1P A;  5AHU B;  3AQC B;  3M9U A;  1V4J A;  4P0V A;  4WK5 A;  1YYT A;  2Z4V A;  3Q1O A;  4XQT F;  3N5H F;  5IM1 A;  4OGU A;  3LMD A;  2E93 A;  4LLT A;  3TC1 A;  2ZCO A;  5B00 A;  3ZMB A;  3KRO A;  5ILH A;  3WCE A;  5B03 A;  4JVJ F;  2Z4Z A;  2AZJ A;  5ILK A;  2E94 A;  1UBW A;  3M02 A;  3ZL6 A;  1N21 A;  2P1C A;  4LPG F;  3B7L A;  3N1W F;  5E8H A;  3SDU A;  3S9V A;  2ZCQ A;  4XQR F;  4LFG A;  5IL8 A;  3RMG A;  3PYA A;  3ADZ A;  5CG6 A;  2Q9Z A;  5EAS A;  3N0G A;  3QQV A;  1WKZ A;  4E9Z A;  5B0L A;  3KB9 A;  1UBX A;  1YYU A;  2F8C F;  4PVY F;  2ZEU A;  1YHL A;  5IK0 A;  1HM4 A;  5A0J A;  2J5C A;  4MC8 A;  3LEE A;  4K10 A;  2Z4X A;  4LTV A;  4JXN A;  2ZY1 A;  2OPM A;  4JYX A;  3DYH A;  5IVG A;  3KRA A;  1JFG A;  1WMW A;  4NFI F;  2F89 F;  2E91 A;  3SAE A;  5DIQ F;  1N24 A;  4KQS A;  3MZV A;  3VJB A;  3N5J F;  2ONG A;  5C05 A;  4DI5 A;  3IBA A;  5A0K A;  4LUU A;  3MAV A;  3RYE A;  3WSA A;  3EGT A;  2E92 A;  1RTR A;  4LZC A;  4N1Z F;  3NPK A;  4OMH A;  5DJV F;  5JV2 F;  4OMG A;  3LVS A;  1V4I A;  4EA0 A;  3KRA B;  3KRF A;  3AQ0 A;  4MC0 A;  2E8T A;  3LGZ B;  5I1U A;  2F94 F;  3WCG A;  2PS8 A;  4RNQ A;  4RYP A;  3TFN A;  5ILY A;  3WCB A;  1V4K A;  2QIS A;  3N45 F;  4LFV F;  4EA2 A;  1VG6 A;  5IMI A;  3WEF A;  4HD1 A;  2Z4Y A;  2AET A;  3ICN A;  1YYS A;  3KRC A;  1N1B A;  3G4F A;  3LJI A;  3SDQ A;  3VJ8 A;  1N20 A;  2Z52 A;  3APZ A;  3N6K F;  1N22 A;  2E8X A;  3WE9 A;  3AQB B;  3V1X A;  4F6X A;  2Z4W A;  2ZCR A;  4OKZ A;  1KIY A;  4E1E A;  5B0K A;  4RXE A;  1DGP A;  4KVY A;  5CG5 A;  5KSX F;  2F7M F;  5JUZ F;  3KRC B;  3PKO A;  4RXA A;  3NRI A;  4QXS F;  4NUA A;  4XQS F;  2AZL A;  3VJD A;  4KVI A;  1YHM A;  3WCJ A;  3N0F A;  3DYG A;  1WL1 A;  5HN7 A;  4JZX A;  1HXA A;  5IL3 A;  4KWD A;  3VJC A;  3WEK A;  4KVD A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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