1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords farnesyl pyrophosphate synthase
publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
4JVJF 3N3LF 3WJOA 2P1CA 4L2XF 2Z50A 5IKAA 1RTRA 3N5JF 2E95A 4HD1A 3TC1A 5A0JA 3EFQA 4DWGA 3EGTA 3KROA 2E8TA 3CKEA 3KRPA 4NKFA 1N22A 4E9ZA 5DGMF 3NPRA 2E91A 1V4IA 4JYXA 3KRAB 3NPKA 3ZCDA 5HNAA 4KVIA 2F8ZF 4JZXA 1YHMA 3KRFB 5DJPF 1YYQA 5DJVF 3G4DA 4OGUA 2E4OA 3WCIA 5DGSF 2J1PA 1YYSA 3WCMA 5ER8A 1UBWA 4GA3A 5ILIA 5DW7A 4KPJA 4LFGA 4LPGF 4WK5A 5ILDA 5IK9A 5EATA 4KFAA 1WL1A 4E1EA 3Q30A 3WCFA 2E90A 3WCHA 5IKHA 3DYGA 4KUXA 5B0IA 3ICMA 5AHUB 1DI1A 4JXNA 4NFIF 3WEIA 5B0JA 1HXAA 4LA5A 3PYBA 1YQ7A 3VJDA 3SDUA 3OABA 4LFVF 1WMWA 5HN7A 3WEHA 2AZKA 3MZVA 3M02A 2DH4A 5DGNF 3VJCA 3VJ9A 4LZCA 3PYAA 3V66A 2E93A 2F7MF 4QXSF 3AE0A 1RQIA 2Z4XA 2Z4ZA 4DI5A 3NF2A 3EZ3A 3P5PA 2ONGA 3LSNA 3SAEA 3LK5A 1YYRA 3LVSA 3ICNA 5IMIA 3ZOUA 4EA2A 5KSXF 1YYTA 2PS8A 4OMGA 2OPMA 1V4JA 2ZCRA 1HXGA 4KPDA 2J1OA 4H5EF 5B01A 2Z78A 5EAUA 4LZ3A 1V4KA 2AZJA 4DZWA 5EASA 5ERMA 2AELA 4LOBA 5IL8A 1RQJA 3S4JA 3N46F 3KRAA 1KIZA 3PDEA 3UCAA 1VG7A 2F9KF 5B0KA 4NFJF 2RAHA 3SDQA 4MC3A 3KRFA 3N3DA 5IN8A 4DWBA 3NRIA 2Z52A 1V4HA 3APZA 5JV2F 4GAXA 4DHDA 4KQSA 4GP1A 5DIQF 4Q23A 5DZ2A 4PVYF 3N45F 3LGKA 3CC9A 4FJQA 3LLWA 2ZCQA 1JFGA 3WJKA 3P8LA 3KBKA 5B03A 3LMDA 3V1VA 3AQBB 4RXDA 3Q2ZA 1V4EA 3WSBA 1YHLA 3N1VF 3OACB 4RXAA 5IMPA 3BNYA 3SDTA 2Q80A 4RYPA 5AELA 4OMHA 3OYRA 3RYWA 2FORA 4F62A 2ZEVA 1YV5A 4EA0A 3LZ9A 4N1ZF 2F89F 1EZFA 4E9UA 3VJ8A 4KWDA 3DYFA 3N6KF 1WY0A 3P8RA 4XQSF 2AZLA 1VG6A 5CG6A 5DHIA 3P5RA 4ZQ8A 2Q58A 1N23A 4K10A 5E8KA 3N5HF 3ZMCA 3WCBA 3WEGA 3WC9A 2PS6A 4KKMA 2OA6A 4JZBA 4LPHF 2E8XA 2PS7A 4QPFA 2VF6A 2H8OA 1N24A 4N9UA 2Z7IA 1JFAA 3LGZB 4OKMA 3ADZA 3RYEA 2ZEUA 4NUAA 3TFNA 3ICKA 2AETA 5B0LA 4LLTA 3AQCB 5E8HA 1HM4A 4NFKF 5H9DA 4LIXA 3WCJA 1N20A 3QKCA 5A0IA 3Q1OA 3WEKA 4H5DF 4NKEA 5AFXA 3WCGA 3M01A 3RBMA 3N1WF 2ZY1A 4EA1A 1HXCA 3ACXA 4KQ5A 1WKZA 4GP2A 3KRCB 3QQVA 5E8LA 2I19A 2PS4A 5JV0F 3WEJA 2E8UA 2E94A 2FTZA 4NG6A 3WCCA 1N1ZA 3WEFA 4UMJA 1YJ4A 1HX9A 4FP4A 2PS5A 4KVWA 5JV1F 5EROA 3TS7A 3M00A 3PKOA 3ACYA 3PH7A 3OACA 2Z7HA 4LA6A 5DHKA 1N21A 5ILKA 3TFVA 5HN9A 2J5CA 1ZW5A 2AEKA 3Q2QA 3P41A 3LEEA 2F8CF 3SDRA 3LOMA 3N0GA 5IK0A 3LG5A 5DJRF 5C05A 2EWGA 4KVYA 4OKZA 2OPNA 3ID0A 3DYHA 2Q9ZA 2ONHA 1UBYA 2QISA 5B0MA 4DXJA 2F94F 5IVGA 5JUZF 3N49F 1KIYA 3KB9A 3CP6A 5IMNA 2Q9YA 1YYUA 3M0GA 3ZMBA 3WSAA 1WL2A 3KROB 5CG5A 3IBAA 3ICZA 4KQUA 4DEMF 3KRPB 4LXWA 4RXCA 1WL3A 4LUUA 5IK6A 4LLSA 1VG3A 2E8VA 3MAVA 1FPSA 5B00A 1PS1A 5JA0F 1WL0A 3V1XA 3VJEA 4LZ0A 3RMGA 2ZCOA 3AQ0A 2ZCSA 2F92F 2Z4VA 3G4FA 3N0FA 4P0XA 2E92A 2OGDA 5ILJA 3WJNA 3BNXA 3M9UA 1DGPA 1UBVA 4JXYA 4XQTF 3WE9A 2Z4WA 4PVXF 3WCEA 3WCAA 3VJBA 3ASXA 3ZL6A 1HM7A 3KRCA 3SDVA 3LJIA 3IPIA 4LTZA 4XQRF 1VG2A 1YHKA 4KVDA 4LFEA 3ACWA 5ERNA 4F6XA 5ILHA 4MC0A 5IL3A 2O1OA 4H5CF 3OABB 3WCDA 3TFPA 2E8WA 4KK2A 1UBXA 4RXEA 1N1BA 5ILYA 3B7LA 2Z4YA 3S9VA 4P0VA 5I1UA 1VG4A 5AYPA 3VJAA 3LDWA 4F6VA 5A0KA 3W7FA 5HN8A 4RNQA 4MC8A 3WCLA 5ILZA 5IM1A 5B02A 4LTVA 4P0WA
chains in the Genus database with same CATH superfamily
4JVJF 3N3LF 3WJOA 2P1CA 4L2XF 2Z50A 5IKAA 1RTRA 3N5JF 2E95A 4HD1A 3TC1A 5A0JA 3EFQA 4DWGA 3EGTA 3KROA 2E8TA 3CKEA 3KRPA 4NKFA 1N22A 4E9ZA 5DGMF 3NPRA 2E91A 1V4IA 4JYXA 3KRAB 3NPKA 3ZCDA 5HNAA 4KVIA 2F8ZF 4JZXA 1YHMA 3KRFB 5DJPF 1YYQA 5DJVF 3G4DA 4OGUA 2E4OA 3WCIA 5DGSF 2J1PA 1YYSA 3WCMA 5ER8A 1UBWA 4GA3A 5ILIA 5DW7A 4KPJA 4LFGA 4LPGF 4WK5A 5ILDA 5IK9A 5EATA 4KFAA 1WL1A 4E1EA 3Q30A 3WCFA 2E90A 3WCHA 5IKHA 3DYGA 4KUXA 5B0IA 3ICMA 5AHUB 1DI1A 4JXNA 4NFIF 3WEIA 5B0JA 1HXAA 4LA5A 3PYBA 1YQ7A 3VJDA 3SDUA 3OABA 4LFVF 1WMWA 5HN7A 3WEHA 2AZKA 3MZVA 3M02A 2DH4A 5DGNF 3VJCA 3VJ9A 4LZCA 3PYAA 3V66A 2E93A 2F7MF 4QXSF 3AE0A 1RQIA 2Z4XA 2Z4ZA 4DI5A 3NF2A 3EZ3A 3P5PA 2ONGA 3LSNA 3SAEA 3LK5A 1YYRA 3LVSA 3ICNA 5IMIA 3ZOUA 4EA2A 5KSXF 1YYTA 2PS8A 4OMGA 2OPMA 1V4JA 2ZCRA 1HXGA 4KPDA 2J1OA 4H5EF 5B01A 2Z78A 5EAUA 4LZ3A 1V4KA 2AZJA 4DZWA 5EASA 5ERMA 2AELA 4LOBA 5IL8A 1RQJA 3S4JA 3N46F 3KRAA 1KIZA 3PDEA 3UCAA 1VG7A 2F9KF 5B0KA 4NFJF 2RAHA 3SDQA 4MC3A 3KRFA 3N3DA 5IN8A 4DWBA 3NRIA 2Z52A 1V4HA 3APZA 5JV2F 4GAXA 4DHDA 4KQSA 4GP1A 5DIQF 4Q23A 5DZ2A 4PVYF 3N45F 3LGKA 3CC9A 4FJQA 3LLWA 2ZCQA 1JFGA 3WJKA 3P8LA 3KBKA 5B03A 3LMDA 3V1VA 3AQBB 4RXDA 3Q2ZA 1V4EA 3WSBA 1YHLA 3N1VF 3OACB 4RXAA 5IMPA 3BNYA 3SDTA 2Q80A 4RYPA 5AELA 4OMHA 3OYRA 3RYWA 2FORA 4F62A 2ZEVA 1YV5A 4EA0A 3LZ9A 4N1ZF 2F89F 1EZFA 4E9UA 3VJ8A 4KWDA 3DYFA 3N6KF 1WY0A 3P8RA 4XQSF 2AZLA 1VG6A 5CG6A 5DHIA 3P5RA 4ZQ8A 2Q58A 1N23A 4K10A 5E8KA 3N5HF 3ZMCA 3WCBA 3WEGA 3WC9A 2PS6A 4KKMA 2OA6A 4JZBA 4LPHF 2E8XA 2PS7A 4QPFA 2VF6A 2H8OA 1N24A 4N9UA 2Z7IA 1JFAA 3LGZB 4OKMA 3ADZA 3RYEA 2ZEUA 4NUAA 3TFNA 3ICKA 2AETA 5B0LA 4LLTA 3AQCB 5E8HA 1HM4A 4NFKF 5H9DA 4LIXA 3WCJA 1N20A 3QKCA 5A0IA 3Q1OA 3WEKA 4H5DF 4NKEA 5AFXA 3WCGA 3M01A 3RBMA 3N1WF 2ZY1A 4EA1A 1HXCA 3ACXA 4KQ5A 1WKZA 4GP2A 3KRCB 3QQVA 5E8LA 2I19A 2PS4A 5JV0F 3WEJA 2E8UA 2E94A 2FTZA 4NG6A 3WCCA 1N1ZA 3WEFA 4UMJA 1YJ4A 1HX9A 4FP4A 2PS5A 4KVWA 5JV1F 5EROA 3TS7A 3M00A 3PKOA 3ACYA 3PH7A 3OACA 2Z7HA 4LA6A 5DHKA 1N21A 5ILKA 3TFVA 5HN9A 2J5CA 1ZW5A 2AEKA 3Q2QA 3P41A 3LEEA 2F8CF 3SDRA 3LOMA 3N0GA 5IK0A 3LG5A 5DJRF 5C05A 2EWGA 4KVYA 4OKZA 2OPNA 3ID0A 3DYHA 2Q9ZA 2ONHA 1UBYA 2QISA 5B0MA 4DXJA 2F94F 5IVGA 5JUZF 3N49F 1KIYA 3KB9A 3CP6A 5IMNA 2Q9YA 1YYUA 3M0GA 3ZMBA 3WSAA 1WL2A 3KROB 5CG5A 3IBAA 3ICZA 4KQUA 4DEMF 3KRPB 4LXWA 4RXCA 1WL3A 4LUUA 5IK6A 4LLSA 1VG3A 2E8VA 3MAVA 1FPSA 5B00A 1PS1A 5JA0F 1WL0A 3V1XA 3VJEA 4LZ0A 3RMGA 2ZCOA 3AQ0A 2ZCSA 2F92F 2Z4VA 3G4FA 3N0FA 4P0XA 2E92A 2OGDA 5ILJA 3WJNA 3BNXA 3M9UA 1DGPA 1UBVA 4JXYA 4XQTF 3WE9A 2Z4WA 4PVXF 3WCEA 3WCAA 3VJBA 3ASXA 3ZL6A 1HM7A 3KRCA 3SDVA 3LJIA 3IPIA 4LTZA 4XQRF 1VG2A 1YHKA 4KVDA 4LFEA 3ACWA 5ERNA 4F6XA 5ILHA 4MC0A 5IL3A 2O1OA 4H5CF 3OABB 3WCDA 3TFPA 2E8WA 4KK2A 1UBXA 4RXEA 1N1BA 5ILYA 3B7LA 2Z4YA 3S9VA 4P0VA 5I1UA 1VG4A 5AYPA 3VJAA 3LDWA 4F6VA 5A0KA 3W7FA 5HN8A 4RNQA 4MC8A 3WCLA 5ILZA 5IM1A 5B02A 4LTVA 4P0WA
chains in the Genus database with same CATH topology
4JVJF 3N3LF 3WJOA 2P1CA 4L2XF 2Z50A 5IKAA 1RTRA 3N5JF 2E95A 4HD1A 3TC1A 5A0JA 3EFQA 4DWGA 3EGTA 3KROA 2E8TA 3CKEA 3KRPA 4NKFA 1N22A 4E9ZA 5DGMF 3NPRA 2E91A 1V4IA 4JYXA 3KRAB 3NPKA 3ZCDA 5HNAA 4KVIA 2F8ZF 4JZXA 1YHMA 3KRFB 5DJPF 1YYQA 5DJVF 3G4DA 4OGUA 2E4OA 3WCIA 5DGSF 2J1PA 1YYSA 3WCMA 5ER8A 1UBWA 4GA3A 5ILIA 5DW7A 4KPJA 4LFGA 4LPGF 4WK5A 5ILDA 5IK9A 5EATA 4KFAA 1WL1A 4E1EA 3Q30A 3WCFA 2E90A 3WCHA 5IKHA 3DYGA 4KUXA 5B0IA 3ICMA 5AHUB 1DI1A 4JXNA 4NFIF 3WEIA 5B0JA 1HXAA 4LA5A 3PYBA 1YQ7A 3VJDA 3SDUA 3OABA 4LFVF 1WMWA 5HN7A 3WEHA 2AZKA 3MZVA 3M02A 2DH4A 5DGNF 3VJCA 3VJ9A 4LZCA 3PYAA 3V66A 2E93A 2F7MF 4QXSF 3AE0A 1RQIA 2Z4XA 2Z4ZA 4DI5A 3NF2A 3EZ3A 3P5PA 2ONGA 3LSNA 3SAEA 3LK5A 1YYRA 3LVSA 3ICNA 5IMIA 3ZOUA 4EA2A 5KSXF 1YYTA 2PS8A 4OMGA 2OPMA 1V4JA 2ZCRA 1HXGA 4KPDA 2J1OA 4H5EF 5B01A 2Z78A 5EAUA 4LZ3A 1V4KA 2AZJA 4DZWA 5EASA 5ERMA 2AELA 4LOBA 5IL8A 1RQJA 3S4JA 3N46F 3KRAA 1KIZA 3PDEA 3UCAA 1VG7A 2F9KF 5B0KA 4NFJF 2RAHA 3SDQA 4MC3A 3KRFA 3N3DA 5IN8A 4DWBA 3NRIA 2Z52A 1V4HA 3APZA 5JV2F 4GAXA 4DHDA 4KQSA 4GP1A 5DIQF 4Q23A 5DZ2A 4PVYF 3N45F 3LGKA 3CC9A 4FJQA 3LLWA 2ZCQA 1JFGA 3WJKA 3P8LA 3KBKA 5B03A 3LMDA 3V1VA 3AQBB 4RXDA 3Q2ZA 1V4EA 3WSBA 1YHLA 3N1VF 3OACB 4RXAA 5IMPA 3BNYA 3SDTA 2Q80A 4RYPA 5AELA 4OMHA 3OYRA 3RYWA 2FORA 4F62A 2ZEVA 1YV5A 4EA0A 3LZ9A 4N1ZF 2F89F 1EZFA 4E9UA 3VJ8A 4KWDA 3DYFA 3N6KF 1WY0A 3P8RA 4XQSF 2AZLA 1VG6A 5CG6A 5DHIA 3P5RA 4ZQ8A 2Q58A 1N23A 4K10A 5E8KA 3N5HF 3ZMCA 3WCBA 3WEGA 3WC9A 2PS6A 4KKMA 2OA6A 4JZBA 4LPHF 2E8XA 2PS7A 4QPFA 2VF6A 2H8OA 1N24A 4N9UA 2Z7IA 1JFAA 3LGZB 4OKMA 3ADZA 3RYEA 2ZEUA 4NUAA 3TFNA 3ICKA 2AETA 5B0LA 4LLTA 3AQCB 5E8HA 1HM4A 4NFKF 5H9DA 4LIXA 3WCJA 1N20A 3QKCA 5A0IA 3Q1OA 3WEKA 4H5DF 4NKEA 5AFXA 3WCGA 3M01A 3RBMA 3N1WF 2ZY1A 4EA1A 1HXCA 3ACXA 4KQ5A 1WKZA 4GP2A 3KRCB 3QQVA 5E8LA 2I19A 2PS4A 5JV0F 3WEJA 2E8UA 2E94A 2FTZA 4NG6A 3WCCA 1N1ZA 3WEFA 4UMJA 1YJ4A 1HX9A 4FP4A 2PS5A 4KVWA 5JV1F 5EROA 3TS7A 3M00A 3PKOA 3ACYA 3PH7A 3OACA 2Z7HA 4LA6A 5DHKA 1N21A 5ILKA 3TFVA 5HN9A 2J5CA 1ZW5A 2AEKA 3Q2QA 3P41A 3LEEA 2F8CF 3SDRA 3LOMA 3N0GA 5IK0A 3LG5A 5DJRF 5C05A 2EWGA 4KVYA 4OKZA 2OPNA 3ID0A 3DYHA 2Q9ZA 2ONHA 1UBYA 2QISA 5B0MA 4DXJA 2F94F 5IVGA 5JUZF 3N49F 1KIYA 3KB9A 3CP6A 5IMNA 2Q9YA 1YYUA 3M0GA 3ZMBA 3WSAA 1WL2A 3KROB 5CG5A 3IBAA 3ICZA 4KQUA 4DEMF 3KRPB 4LXWA 4RXCA 1WL3A 4LUUA 5IK6A 4LLSA 1VG3A 2E8VA 3MAVA 1FPSA 5B00A 1PS1A 5JA0F 1WL0A 3V1XA 3VJEA 4LZ0A 3RMGA 2ZCOA 3AQ0A 2ZCSA 2F92F 2Z4VA 3G4FA 3N0FA 4P0XA 2E92A 2OGDA 5ILJA 3WJNA 3BNXA 3M9UA 1DGPA 1UBVA 4JXYA 4XQTF 3WE9A 2Z4WA 4PVXF 3WCEA 3WCAA 3VJBA 3ASXA 3ZL6A 1HM7A 3KRCA 3SDVA 3LJIA 3IPIA 4LTZA 4XQRF 1VG2A 1YHKA 4KVDA 4LFEA 3ACWA 5ERNA 4F6XA 5ILHA 4MC0A 5IL3A 2O1OA 4H5CF 3OABB 3WCDA 3TFPA 2E8WA 4KK2A 1UBXA 4RXEA 1N1BA 5ILYA 3B7LA 2Z4YA 3S9VA 4P0VA 5I1UA 1VG4A 5AYPA 3VJAA 3LDWA 4F6VA 5A0KA 3W7FA 5HN8A 4RNQA 4MC8A 3WCLA 5ILZA 5IM1A 5B02A 4LTVA 4P0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JVJ F;  3N3L F;  3WJO A;  2P1C A;  4L2X F;  2Z50 A;  5IKA A;  1RTR A;  3N5J F;  2E95 A;  4HD1 A;  3TC1 A;  5A0J A;  3EFQ A;  4DWG A;  3EGT A;  3KRO A;  2E8T A;  3CKE A;  3KRP A;  4NKF A;  1N22 A;  4E9Z A;  5DGM F;  3NPR A;  2E91 A;  1V4I A;  4JYX A;  3KRA B;  3NPK A;  3ZCD A;  5HNA A;  4KVI A;  2F8Z F;  4JZX A;  1YHM A;  3KRF B;  5DJP F;  1YYQ A;  5DJV F;  3G4D A;  4OGU A;  2E4O A;  3WCI A;  5DGS F;  2J1P A;  1YYS A;  3WCM A;  5ER8 A;  1UBW A;  4GA3 A;  5ILI A;  5DW7 A;  4KPJ A;  4LFG A;  4LPG F;  4WK5 A;  5ILD A;  5IK9 A;  5EAT A;  4KFA A;  1WL1 A;  4E1E A;  3Q30 A;  3WCF A;  2E90 A;  3WCH A;  5IKH A;  3DYG A;  4KUX A;  5B0I A;  3ICM A;  5AHU B;  1DI1 A;  4JXN A;  4NFI F;  3WEI A;  5B0J A;  1HXA A;  4LA5 A;  3PYB A;  1YQ7 A;  3VJD A;  3SDU A;  3OAB A;  4LFV F;  1WMW A;  5HN7 A;  3WEH A;  2AZK A;  3MZV A;  3M02 A;  2DH4 A;  5DGN F;  3VJC A;  3VJ9 A;  4LZC A;  3PYA A;  3V66 A;  2E93 A;  2F7M F;  4QXS F;  3AE0 A;  1RQI A;  2Z4X A;  2Z4Z A;  4DI5 A;  3NF2 A;  3EZ3 A;  3P5P A;  2ONG A;  3LSN A;  3SAE A;  3LK5 A;  1YYR A;  3LVS A;  3ICN A;  5IMI A;  3ZOU A;  4EA2 A;  5KSX F;  1YYT A;  2PS8 A;  4OMG A;  2OPM A;  1V4J A;  2ZCR A;  1HXG A;  4KPD A;  2J1O A;  4H5E F;  5B01 A;  2Z78 A;  5EAU A;  4LZ3 A;  1V4K A;  2AZJ A;  4DZW A;  5EAS A;  5ERM A;  2AEL A;  4LOB A;  5IL8 A;  1RQJ A;  3S4J A;  3N46 F;  3KRA A;  1KIZ A;  3PDE A;  3UCA A;  1VG7 A;  2F9K F;  5B0K A;  4NFJ F;  2RAH A;  3SDQ A;  4MC3 A;  3KRF A;  3N3D A;  5IN8 A;  4DWB A;  3NRI A;  2Z52 A;  1V4H A;  3APZ A;  5JV2 F;  4GAX A;  4DHD A;  4KQS A;  4GP1 A;  5DIQ F;  4Q23 A;  5DZ2 A;  4PVY F;  3N45 F;  3LGK A;  3CC9 A;  4FJQ A;  3LLW A;  2ZCQ A;  1JFG A;  3WJK A;  3P8L A;  3KBK A;  5B03 A;  3LMD A;  3V1V A;  3AQB B;  4RXD A;  3Q2Z A;  1V4E A;  3WSB A;  1YHL A;  3N1V F;  3OAC B;  4RXA A;  5IMP A;  3BNY A;  3SDT A;  2Q80 A;  4RYP A;  5AEL A;  4OMH A;  3OYR A;  3RYW A;  2FOR A;  4F62 A;  2ZEV A;  1YV5 A;  4EA0 A;  3LZ9 A;  4N1Z F;  2F89 F;  1EZF A;  4E9U A;  3VJ8 A;  4KWD A;  3DYF A;  3N6K F;  1WY0 A;  3P8R A;  4XQS F;  2AZL A;  1VG6 A;  5CG6 A;  5DHI A;  3P5R A;  4ZQ8 A;  2Q58 A;  1N23 A;  4K10 A;  5E8K A;  3N5H F;  3ZMC A;  3WCB A;  3WEG A;  3WC9 A;  2PS6 A;  4KKM A;  2OA6 A;  4JZB A;  4LPH F;  2E8X A;  2PS7 A;  4QPF A;  2VF6 A;  2H8O A;  1N24 A;  4N9U A;  2Z7I A;  1JFA A;  3LGZ B;  4OKM A;  3ADZ A;  3RYE A;  2ZEU A;  4NUA A;  3TFN A;  3ICK A;  2AET A;  5B0L A;  4LLT A;  3AQC B;  5E8H A;  1HM4 A;  4NFK F;  5H9D A;  4LIX A;  3WCJ A;  1N20 A;  3QKC A;  5A0I A;  3Q1O A;  3WEK A;  4H5D F;  4NKE A;  5AFX A;  3WCG A;  3M01 A;  3RBM A;  3N1W F;  2ZY1 A;  4EA1 A;  1HXC A;  3ACX A;  4KQ5 A;  1WKZ A;  4GP2 A;  3KRC B;  3QQV A;  5E8L A;  2I19 A;  2PS4 A;  5JV0 F;  3WEJ A;  2E8U A;  2E94 A;  2FTZ A;  4NG6 A;  3WCC A;  1N1Z A;  3WEF A;  4UMJ A;  1YJ4 A;  1HX9 A;  4FP4 A;  2PS5 A;  4KVW A;  5JV1 F;  5ERO A;  3TS7 A;  3M00 A;  3PKO A;  3ACY A;  3PH7 A;  3OAC A;  2Z7H A;  4LA6 A;  5DHK A;  1N21 A;  5ILK A;  3TFV A;  5HN9 A;  2J5C A;  1ZW5 A;  2AEK A;  3Q2Q A;  3P41 A;  3LEE A;  2F8C F;  3SDR A;  3LOM A;  3N0G A;  5IK0 A;  3LG5 A;  5DJR F;  5C05 A;  2EWG A;  4KVY A;  4OKZ A;  2OPN A;  3ID0 A;  3DYH A;  2Q9Z A;  2ONH A;  1UBY A;  2QIS A;  5B0M A;  4DXJ A;  2F94 F;  5IVG A;  5JUZ F;  3N49 F;  1KIY A;  3KB9 A;  3CP6 A;  5IMN A;  2Q9Y A;  1YYU A;  3M0G A;  3ZMB A;  3WSA A;  1WL2 A;  3KRO B;  5CG5 A;  3IBA A;  3ICZ A;  4KQU A;  4DEM F;  3KRP B;  4LXW A;  4RXC A;  1WL3 A;  4LUU A;  5IK6 A;  4LLS A;  1VG3 A;  2E8V A;  3MAV A;  1FPS A;  5B00 A;  1PS1 A;  5JA0 F;  1WL0 A;  3V1X A;  3VJE A;  4LZ0 A;  3RMG A;  2ZCO A;  3AQ0 A;  2ZCS A;  2F92 F;  2Z4V A;  3G4F A;  3N0F A;  4P0X A;  2E92 A;  2OGD A;  5ILJ A;  3WJN A;  3BNX A;  3M9U A;  1DGP A;  1UBV A;  4JXY A;  4XQT F;  3WE9 A;  2Z4W A;  4PVX F;  3WCE A;  3WCA A;  3VJB A;  3ASX A;  3ZL6 A;  1HM7 A;  3KRC A;  3SDV A;  3LJI A;  3IPI A;  4LTZ A;  4XQR F;  1VG2 A;  1YHK A;  4KVD A;  4LFE A;  3ACW A;  5ERN A;  4F6X A;  5ILH A;  4MC0 A;  5IL3 A;  2O1O A;  4H5C F;  3OAB B;  3WCD A;  3TFP A;  2E8W A;  4KK2 A;  1UBX A;  4RXE A;  1N1B A;  5ILY A;  3B7L A;  2Z4Y A;  3S9V A;  4P0V A;  5I1U A;  1VG4 A;  5AYP A;  3VJA A;  3LDW A;  4F6V A;  5A0K A;  3W7F A;  5HN8 A;  4RNQ A;  4MC8 A;  3WCL A;  5ILZ A;  5IM1 A;  5B02 A;  4LTV A;  4P0W A; 
#chains in the Genus database with same CATH topology
 4JVJ F;  3N3L F;  3WJO A;  2P1C A;  4L2X F;  2Z50 A;  5IKA A;  1RTR A;  3N5J F;  2E95 A;  4HD1 A;  3TC1 A;  5A0J A;  3EFQ A;  4DWG A;  3EGT A;  3KRO A;  2E8T A;  3CKE A;  3KRP A;  4NKF A;  1N22 A;  4E9Z A;  5DGM F;  3NPR A;  2E91 A;  1V4I A;  4JYX A;  3KRA B;  3NPK A;  3ZCD A;  5HNA A;  4KVI A;  2F8Z F;  4JZX A;  1YHM A;  3KRF B;  5DJP F;  1YYQ A;  5DJV F;  3G4D A;  4OGU A;  2E4O A;  3WCI A;  5DGS F;  2J1P A;  1YYS A;  3WCM A;  5ER8 A;  1UBW A;  4GA3 A;  5ILI A;  5DW7 A;  4KPJ A;  4LFG A;  4LPG F;  4WK5 A;  5ILD A;  5IK9 A;  5EAT A;  4KFA A;  1WL1 A;  4E1E A;  3Q30 A;  3WCF A;  2E90 A;  3WCH A;  5IKH A;  3DYG A;  4KUX A;  5B0I A;  3ICM A;  5AHU B;  1DI1 A;  4JXN A;  4NFI F;  3WEI A;  5B0J A;  1HXA A;  4LA5 A;  3PYB A;  1YQ7 A;  3VJD A;  3SDU A;  3OAB A;  4LFV F;  1WMW A;  5HN7 A;  3WEH A;  2AZK A;  3MZV A;  3M02 A;  2DH4 A;  5DGN F;  3VJC A;  3VJ9 A;  4LZC A;  3PYA A;  3V66 A;  2E93 A;  2F7M F;  4QXS F;  3AE0 A;  1RQI A;  2Z4X A;  2Z4Z A;  4DI5 A;  3NF2 A;  3EZ3 A;  3P5P A;  2ONG A;  3LSN A;  3SAE A;  3LK5 A;  1YYR A;  3LVS A;  3ICN A;  5IMI A;  3ZOU A;  4EA2 A;  5KSX F;  1YYT A;  2PS8 A;  4OMG A;  2OPM A;  1V4J A;  2ZCR A;  1HXG A;  4KPD A;  2J1O A;  4H5E F;  5B01 A;  2Z78 A;  5EAU A;  4LZ3 A;  1V4K A;  2AZJ A;  4DZW A;  5EAS A;  5ERM A;  2AEL A;  4LOB A;  5IL8 A;  1RQJ A;  3S4J A;  3N46 F;  3KRA A;  1KIZ A;  3PDE A;  3UCA A;  1VG7 A;  2F9K F;  5B0K A;  4NFJ F;  2RAH A;  3SDQ A;  4MC3 A;  3KRF A;  3N3D A;  5IN8 A;  4DWB A;  3NRI A;  2Z52 A;  1V4H A;  3APZ A;  5JV2 F;  4GAX A;  4DHD A;  4KQS A;  4GP1 A;  5DIQ F;  4Q23 A;  5DZ2 A;  4PVY F;  3N45 F;  3LGK A;  3CC9 A;  4FJQ A;  3LLW A;  2ZCQ A;  1JFG A;  3WJK A;  3P8L A;  3KBK A;  5B03 A;  3LMD A;  3V1V A;  3AQB B;  4RXD A;  3Q2Z A;  1V4E A;  3WSB A;  1YHL A;  3N1V F;  3OAC B;  4RXA A;  5IMP A;  3BNY A;  3SDT A;  2Q80 A;  4RYP A;  5AEL A;  4OMH A;  3OYR A;  3RYW A;  2FOR A;  4F62 A;  2ZEV A;  1YV5 A;  4EA0 A;  3LZ9 A;  4N1Z F;  2F89 F;  1EZF A;  4E9U A;  3VJ8 A;  4KWD A;  3DYF A;  3N6K F;  1WY0 A;  3P8R A;  4XQS F;  2AZL A;  1VG6 A;  5CG6 A;  5DHI A;  3P5R A;  4ZQ8 A;  2Q58 A;  1N23 A;  4K10 A;  5E8K A;  3N5H F;  3ZMC A;  3WCB A;  3WEG A;  3WC9 A;  2PS6 A;  4KKM A;  2OA6 A;  4JZB A;  4LPH F;  2E8X A;  2PS7 A;  4QPF A;  2VF6 A;  2H8O A;  1N24 A;  4N9U A;  2Z7I A;  1JFA A;  3LGZ B;  4OKM A;  3ADZ A;  3RYE A;  2ZEU A;  4NUA A;  3TFN A;  3ICK A;  2AET A;  5B0L A;  4LLT A;  3AQC B;  5E8H A;  1HM4 A;  4NFK F;  5H9D A;  4LIX A;  3WCJ A;  1N20 A;  3QKC A;  5A0I A;  3Q1O A;  3WEK A;  4H5D F;  4NKE A;  5AFX A;  3WCG A;  3M01 A;  3RBM A;  3N1W F;  2ZY1 A;  4EA1 A;  1HXC A;  3ACX A;  4KQ5 A;  1WKZ A;  4GP2 A;  3KRC B;  3QQV A;  5E8L A;  2I19 A;  2PS4 A;  5JV0 F;  3WEJ A;  2E8U A;  2E94 A;  2FTZ A;  4NG6 A;  3WCC A;  1N1Z A;  3WEF A;  4UMJ A;  1YJ4 A;  1HX9 A;  4FP4 A;  2PS5 A;  4KVW A;  5JV1 F;  5ERO A;  3TS7 A;  3M00 A;  3PKO A;  3ACY A;  3PH7 A;  3OAC A;  2Z7H A;  4LA6 A;  5DHK A;  1N21 A;  5ILK A;  3TFV A;  5HN9 A;  2J5C A;  1ZW5 A;  2AEK A;  3Q2Q A;  3P41 A;  3LEE A;  2F8C F;  3SDR A;  3LOM A;  3N0G A;  5IK0 A;  3LG5 A;  5DJR F;  5C05 A;  2EWG A;  4KVY A;  4OKZ A;  2OPN A;  3ID0 A;  3DYH A;  2Q9Z A;  2ONH A;  1UBY A;  2QIS A;  5B0M A;  4DXJ A;  2F94 F;  5IVG A;  5JUZ F;  3N49 F;  1KIY A;  3KB9 A;  3CP6 A;  5IMN A;  2Q9Y A;  1YYU A;  3M0G A;  3ZMB A;  3WSA A;  1WL2 A;  3KRO B;  5CG5 A;  3IBA A;  3ICZ A;  4KQU A;  4DEM F;  3KRP B;  4LXW A;  4RXC A;  1WL3 A;  4LUU A;  5IK6 A;  4LLS A;  1VG3 A;  2E8V A;  3MAV A;  1FPS A;  5B00 A;  1PS1 A;  5JA0 F;  1WL0 A;  3V1X A;  3VJE A;  4LZ0 A;  3RMG A;  2ZCO A;  3AQ0 A;  2ZCS A;  2F92 F;  2Z4V A;  3G4F A;  3N0F A;  4P0X A;  2E92 A;  2OGD A;  5ILJ A;  3WJN A;  3BNX A;  3M9U A;  1DGP A;  1UBV A;  4JXY A;  4XQT F;  3WE9 A;  2Z4W A;  4PVX F;  3WCE A;  3WCA A;  3VJB A;  3ASX A;  3ZL6 A;  1HM7 A;  3KRC A;  3SDV A;  3LJI A;  3IPI A;  4LTZ A;  4XQR F;  1VG2 A;  1YHK A;  4KVD A;  4LFE A;  3ACW A;  5ERN A;  4F6X A;  5ILH A;  4MC0 A;  5IL3 A;  2O1O A;  4H5C F;  3OAB B;  3WCD A;  3TFP A;  2E8W A;  4KK2 A;  1UBX A;  4RXE A;  1N1B A;  5ILY A;  3B7L A;  2Z4Y A;  3S9V A;  4P0V A;  5I1U A;  1VG4 A;  5AYP A;  3VJA A;  3LDW A;  4F6V A;  5A0K A;  3W7F A;  5HN8 A;  4RNQ A;  4MC8 A;  3WCL A;  5ILZ A;  5IM1 A;  5B02 A;  4LTV A;  4P0W A; 
#chains in the Genus database with same CATH homology
 4JVJ F;  3N3L F;  3WJO A;  2P1C A;  4L2X F;  2Z50 A;  5IKA A;  1RTR A;  3N5J F;  2E95 A;  4HD1 A;  3TC1 A;  5A0J A;  3EFQ A;  4DWG A;  3EGT A;  3KRO A;  2E8T A;  3CKE A;  3KRP A;  4NKF A;  1N22 A;  4E9Z A;  5DGM F;  3NPR A;  2E91 A;  1V4I A;  4JYX A;  3KRA B;  3NPK A;  3ZCD A;  5HNA A;  4KVI A;  2F8Z F;  4JZX A;  1YHM A;  3KRF B;  5DJP F;  1YYQ A;  5DJV F;  3G4D A;  4OGU A;  2E4O A;  3WCI A;  5DGS F;  2J1P A;  1YYS A;  3WCM A;  5ER8 A;  1UBW A;  4GA3 A;  5ILI A;  5DW7 A;  4KPJ A;  4LFG A;  4LPG F;  4WK5 A;  5ILD A;  5IK9 A;  5EAT A;  4KFA A;  1WL1 A;  4E1E A;  3Q30 A;  3WCF A;  2E90 A;  3WCH A;  5IKH A;  3DYG A;  4KUX A;  5B0I A;  3ICM A;  5AHU B;  1DI1 A;  4JXN A;  4NFI F;  3WEI A;  5B0J A;  1HXA A;  4LA5 A;  3PYB A;  1YQ7 A;  3VJD A;  3SDU A;  3OAB A;  4LFV F;  1WMW A;  5HN7 A;  3WEH A;  2AZK A;  3MZV A;  3M02 A;  2DH4 A;  5DGN F;  3VJC A;  3VJ9 A;  4LZC A;  3PYA A;  3V66 A;  2E93 A;  2F7M F;  4QXS F;  3AE0 A;  1RQI A;  2Z4X A;  2Z4Z A;  4DI5 A;  3NF2 A;  3EZ3 A;  3P5P A;  2ONG A;  3LSN A;  3SAE A;  3LK5 A;  1YYR A;  3LVS A;  3ICN A;  5IMI A;  3ZOU A;  4EA2 A;  5KSX F;  1YYT A;  2PS8 A;  4OMG A;  2OPM A;  1V4J A;  2ZCR A;  1HXG A;  4KPD A;  2J1O A;  4H5E F;  5B01 A;  2Z78 A;  5EAU A;  4LZ3 A;  1V4K A;  2AZJ A;  4DZW A;  5EAS A;  5ERM A;  2AEL A;  4LOB A;  5IL8 A;  1RQJ A;  3S4J A;  3N46 F;  3KRA A;  1KIZ A;  3PDE A;  3UCA A;  1VG7 A;  2F9K F;  5B0K A;  4NFJ F;  2RAH A;  3SDQ A;  4MC3 A;  3KRF A;  3N3D A;  5IN8 A;  4DWB A;  3NRI A;  2Z52 A;  1V4H A;  3APZ A;  5JV2 F;  4GAX A;  4DHD A;  4KQS A;  4GP1 A;  5DIQ F;  4Q23 A;  5DZ2 A;  4PVY F;  3N45 F;  3LGK A;  3CC9 A;  4FJQ A;  3LLW A;  2ZCQ A;  1JFG A;  3WJK A;  3P8L A;  3KBK A;  5B03 A;  3LMD A;  3V1V A;  3AQB B;  4RXD A;  3Q2Z A;  1V4E A;  3WSB A;  1YHL A;  3N1V F;  3OAC B;  4RXA A;  5IMP A;  3BNY A;  3SDT A;  2Q80 A;  4RYP A;  5AEL A;  4OMH A;  3OYR A;  3RYW A;  2FOR A;  4F62 A;  2ZEV A;  1YV5 A;  4EA0 A;  3LZ9 A;  4N1Z F;  2F89 F;  1EZF A;  4E9U A;  3VJ8 A;  4KWD A;  3DYF A;  3N6K F;  1WY0 A;  3P8R A;  4XQS F;  2AZL A;  1VG6 A;  5CG6 A;  5DHI A;  3P5R A;  4ZQ8 A;  2Q58 A;  1N23 A;  4K10 A;  5E8K A;  3N5H F;  3ZMC A;  3WCB A;  3WEG A;  3WC9 A;  2PS6 A;  4KKM A;  2OA6 A;  4JZB A;  4LPH F;  2E8X A;  2PS7 A;  4QPF A;  2VF6 A;  2H8O A;  1N24 A;  4N9U A;  2Z7I A;  1JFA A;  3LGZ B;  4OKM A;  3ADZ A;  3RYE A;  2ZEU A;  4NUA A;  3TFN A;  3ICK A;  2AET A;  5B0L A;  4LLT A;  3AQC B;  5E8H A;  1HM4 A;  4NFK F;  5H9D A;  4LIX A;  3WCJ A;  1N20 A;  3QKC A;  5A0I A;  3Q1O A;  3WEK A;  4H5D F;  4NKE A;  5AFX A;  3WCG A;  3M01 A;  3RBM A;  3N1W F;  2ZY1 A;  4EA1 A;  1HXC A;  3ACX A;  4KQ5 A;  1WKZ A;  4GP2 A;  3KRC B;  3QQV A;  5E8L A;  2I19 A;  2PS4 A;  5JV0 F;  3WEJ A;  2E8U A;  2E94 A;  2FTZ A;  4NG6 A;  3WCC A;  1N1Z A;  3WEF A;  4UMJ A;  1YJ4 A;  1HX9 A;  4FP4 A;  2PS5 A;  4KVW A;  5JV1 F;  5ERO A;  3TS7 A;  3M00 A;  3PKO A;  3ACY A;  3PH7 A;  3OAC A;  2Z7H A;  4LA6 A;  5DHK A;  1N21 A;  5ILK A;  3TFV A;  5HN9 A;  2J5C A;  1ZW5 A;  2AEK A;  3Q2Q A;  3P41 A;  3LEE A;  2F8C F;  3SDR A;  3LOM A;  3N0G A;  5IK0 A;  3LG5 A;  5DJR F;  5C05 A;  2EWG A;  4KVY A;  4OKZ A;  2OPN A;  3ID0 A;  3DYH A;  2Q9Z A;  2ONH A;  1UBY A;  2QIS A;  5B0M A;  4DXJ A;  2F94 F;  5IVG A;  5JUZ F;  3N49 F;  1KIY A;  3KB9 A;  3CP6 A;  5IMN A;  2Q9Y A;  1YYU A;  3M0G A;  3ZMB A;  3WSA A;  1WL2 A;  3KRO B;  5CG5 A;  3IBA A;  3ICZ A;  4KQU A;  4DEM F;  3KRP B;  4LXW A;  4RXC A;  1WL3 A;  4LUU A;  5IK6 A;  4LLS A;  1VG3 A;  2E8V A;  3MAV A;  1FPS A;  5B00 A;  1PS1 A;  5JA0 F;  1WL0 A;  3V1X A;  3VJE A;  4LZ0 A;  3RMG A;  2ZCO A;  3AQ0 A;  2ZCS A;  2F92 F;  2Z4V A;  3G4F A;  3N0F A;  4P0X A;  2E92 A;  2OGD A;  5ILJ A;  3WJN A;  3BNX A;  3M9U A;  1DGP A;  1UBV A;  4JXY A;  4XQT F;  3WE9 A;  2Z4W A;  4PVX F;  3WCE A;  3WCA A;  3VJB A;  3ASX A;  3ZL6 A;  1HM7 A;  3KRC A;  3SDV A;  3LJI A;  3IPI A;  4LTZ A;  4XQR F;  1VG2 A;  1YHK A;  4KVD A;  4LFE A;  3ACW A;  5ERN A;  4F6X A;  5ILH A;  4MC0 A;  5IL3 A;  2O1O A;  4H5C F;  3OAB B;  3WCD A;  3TFP A;  2E8W A;  4KK2 A;  1UBX A;  4RXE A;  1N1B A;  5ILY A;  3B7L A;  2Z4Y A;  3S9V A;  4P0V A;  5I1U A;  1VG4 A;  5AYP A;  3VJA A;  3LDW A;  4F6V A;  5A0K A;  3W7F A;  5HN8 A;  4RNQ A;  4MC8 A;  3WCL A;  5ILZ A;  5IM1 A;  5B02 A;  4LTV A;  4P0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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