1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
molecule keywords farnesyl pyrophosphate synthase
molecule tags Transferase
source organism Trypanosoma cruzi
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
3CP6A 2RAHA 3KRAB 2E91A 4DWGA 2ONHA 5DIQF 3Q30A 3Q2ZA 2Q80A 4XQTF 3WCBA 3WCDA 4XQSF 3ZCDA 4LUUA 2F89F 3AQ0A 2Q9YA 3KROB 4KPDA 3TC1A 3TFPA 2J5CA 3KRPB 3SAEA 4LA6A 4LFEA 5DW7A 5JV0F 2Z7HA 4LIXA 3SDUA 1DI1A 3WE9A 4GP1A 3M00A 5AHUB 5B00A 1VG2A 4LFVF 3W7FA 3EZ3A 3KB9A 5ERNA 3P41A 2OA6A 5H9DA 5ILZA 5CG5A 1WKZA 5ILYA 5ILHA 4K10A 3LSNA 4E9UA 5E8HA 2Z78A 4UMJA 3VJ9A 5ILKA 3TS7A 3BNYA 1UBXA 5KSXF 2I19A 4E9ZA 3N45F 3QKCA 5DGSF 4LPHF 3ZMBA 3P8LA 1VG3A 5EATA 4DZWA 5A0IA 3LMDA 1N23A 4LZ0A 3N5JF 1RQJA 4OKMA 5B0IA 3M01A 3CC9A 1ZW5A 5IL8A 4OKZA 3ADZA 5EASA 4P0WA 5IM1A 4RYPA 1EZFA 3S9VA 4EA2A 3BNXA 3OACA 4JXYA 2E8UA 4DI5A 1HXAA 3NF2A 4NFKF 3N46F 1YYQA 3DYGA 1KIYA 3WCAA 4KK2A 5JA0F 1WL1A 4HD1A 4RXDA 4XQRF 4JZXA 1N24A 4JVJF 5DHIA 5ILIA 5HN7A 3WCFA 3WCLA 2Z52A 3EFQA 4FJQA 2Z7IA 2AEKA 3ZL6A 3NPRA 3WCGA 4KVYA 3IBAA 4OGUA 4WK5A 5AFXA 2Q9ZA 1WL3A 4JXNA 3WCIA 2AZJA 3AQCB 5IK9A 1WY0A 3G4FA 2F92F 2ZCOA 3WCJA 3ASXA 3OYRA 4LZCA 4NUAA 3KBKA 2OGDA 1N21A 3WEIA 1YHLA 3LOMA 5IKAA 2VF6A 3RYEA 4F62A 2Z50A 4F6VA 3N3LF 3KRFA 3LLWA 4KPJA 2AZKA 1FPSA 1VG6A 4MC3A 3WEJA 3ICMA 4KFAA 2H8OA 3ZOUA 5B0LA 2DH4A 1YV5A 3KRCA 3OABB 3P5PA 1UBYA 4LLSA 4KKMA 2EWGA 1YYTA 2E90A 3AQBB 4MC8A 5JV1F 3N1VF 4LPGF 4JZBA 2AELA 4RNQA 3VJBA 3QQVA 5DZ2A 4KVWA 2ZCQA 2E4OA 1HXGA 4NFJF 5IMIA 3LVSA 3N3DA 3WSAA 3LK5A 3WJNA 5E8LA 2FORA 4ZQ8A 2ONGA 3V66A 4KQSA 4RXCA 3LGKA 4GAXA 2F8CF 4N1ZF 5IMPA 4GA3A 3VJEA 3RYWA 4OMGA 3Q2QA 4P0XA 5IK0A 3RMGA 4LA5A 5AYPA 2AZLA 3PKOA 3WEFA 3NRIA 3S4JA 3ICKA 3IPIA 3APZA 5HN9A 1YQ7A 5IMNA 5I1UA 3G4DA 5HNAA 3ICZA 2OPNA 4F6XA 2Z4YA 1JFAA 4MC0A 2E8XA 3Q1OA 5B03A 1V4EA 5DGNF 2E92A 1YYRA 3KROA 1N1ZA 4LFGA 3SDVA 5B0KA 1YYSA 1RQIA 4NFIF 1YYUA 2E94A 3ACYA 4E1EA 5DJRF 1WL2A 1UBVA 3N6KF 2AETA 1UBWA 5IKHA 5JV2F 3EGTA 3SDTA 2FTZA 1HM7A 3LEEA 3V1VA 1KIZA 4P0VA 1HXCA 3UCAA 4LXWA 5DJPF 3SDQA 3TFVA 3M02A 5ILJA 4H5DF 2J1PA 2QISA 3WCEA 3ZMCA 2PS4A 3ACXA 3V1XA 3WCMA 4RXAA 3LGZB 5JUZF 3OACB 5B02A 4LLTA 3N5HF 2PS5A 4DEMF 3WC9A 3LJIA 3N49F 5IL3A 3M0GA 2P1CA 2F94F 4L2XF 4NKFA 5ERMA 2F9KF 2ZEVA 3CKEA 5DHKA 1YHMA 5HN8A 3SDRA 4NG6A 3VJDA 1N1BA 3N1WF 1V4JA 3PH7A 5IN8A 3LG5A 4KQUA 3P5RA 2E8WA 4FP4A 3ID0A 1WMWA 3WEKA 4DHDA 2E8VA 2E95A 2E93A 5ILDA 3WJKA 3P8RA 2Q58A 3AE0A 5DJVF 4LOBA 1N22A 2OPMA 5CG6A 4Q23A 1RTRA 2O1OA 4LZ3A 4PVXF 2F7MF 2ZCRA 3N0GA 3PYBA 4LTZA 1WL0A 3DYHA 4KQ5A 3VJAA 3WCCA 3M9UA 3WCHA 1DGPA 2PS6A 4EA0A 4PVYF 4QXSF 3TFNA 2PS8A 3KRFB 4H5EF 2Z4ZA 2F8ZF 5A0JA 2Z4XA 3ACWA 3KRAA 1V4HA 1VG4A 4QPFA 4KVIA 3MZVA 3NPKA 4H5CF 5B01A 4JYXA 4KVDA 2PS7A 3WJOA 5EROA 2Z4WA 5IK6A 4GP2A 3LDWA 4NKEA 4N9UA 3KRCB 1JFGA 5B0JA 2ZEUA 2ZCSA 4LTVA 4EA1A 3MAVA 2E8TA 3PYAA 4KWDA 5EAUA 3KRPA 1VG7A 3VJCA 5B0MA 1YHKA 1V4IA 4KUXA 2ZY1A 3ICNA 5C05A 5AELA 1N20A 3DYFA 5A0KA 4DWBA 3LZ9A 1HM4A 3WSBA 5DGMF 3RBMA 3PDEA 3WEHA 3WEGA 2Z4VA 4DXJA 2J1OA 1HX9A 3B7LA 4RXEA 1PS1A 3OABA 3N0FA 1YJ4A 4OMHA 3VJ8A 5E8KA 5ER8A 5IVGA 1V4KA
chains in the Genus database with same CATH superfamily
3CP6A 2RAHA 3KRAB 2E91A 4DWGA 2ONHA 5DIQF 3Q30A 3Q2ZA 2Q80A 4XQTF 3WCBA 3WCDA 4XQSF 3ZCDA 4LUUA 2F89F 3AQ0A 2Q9YA 3KROB 4KPDA 3TC1A 3TFPA 2J5CA 3KRPB 3SAEA 4LA6A 4LFEA 5DW7A 5JV0F 2Z7HA 4LIXA 3SDUA 1DI1A 3WE9A 4GP1A 3M00A 5AHUB 5B00A 1VG2A 4LFVF 3W7FA 3EZ3A 3KB9A 5ERNA 3P41A 2OA6A 5H9DA 5ILZA 5CG5A 1WKZA 5ILYA 5ILHA 4K10A 3LSNA 4E9UA 5E8HA 2Z78A 4UMJA 3VJ9A 5ILKA 3TS7A 3BNYA 1UBXA 5KSXF 2I19A 4E9ZA 3N45F 3QKCA 5DGSF 4LPHF 3ZMBA 3P8LA 1VG3A 5EATA 4DZWA 5A0IA 3LMDA 1N23A 4LZ0A 3N5JF 1RQJA 4OKMA 5B0IA 3M01A 3CC9A 1ZW5A 5IL8A 4OKZA 3ADZA 5EASA 4P0WA 5IM1A 4RYPA 1EZFA 3S9VA 4EA2A 3BNXA 3OACA 4JXYA 2E8UA 4DI5A 1HXAA 3NF2A 4NFKF 3N46F 1YYQA 3DYGA 1KIYA 3WCAA 4KK2A 5JA0F 1WL1A 4HD1A 4RXDA 4XQRF 4JZXA 1N24A 4JVJF 5DHIA 5ILIA 5HN7A 3WCFA 3WCLA 2Z52A 3EFQA 4FJQA 2Z7IA 2AEKA 3ZL6A 3NPRA 3WCGA 4KVYA 3IBAA 4OGUA 4WK5A 5AFXA 2Q9ZA 1WL3A 4JXNA 3WCIA 2AZJA 3AQCB 5IK9A 1WY0A 3G4FA 2F92F 2ZCOA 3WCJA 3ASXA 3OYRA 4LZCA 4NUAA 3KBKA 2OGDA 1N21A 3WEIA 1YHLA 3LOMA 5IKAA 2VF6A 3RYEA 4F62A 2Z50A 4F6VA 3N3LF 3KRFA 3LLWA 4KPJA 2AZKA 1FPSA 1VG6A 4MC3A 3WEJA 3ICMA 4KFAA 2H8OA 3ZOUA 5B0LA 2DH4A 1YV5A 3KRCA 3OABB 3P5PA 1UBYA 4LLSA 4KKMA 2EWGA 1YYTA 2E90A 3AQBB 4MC8A 5JV1F 3N1VF 4LPGF 4JZBA 2AELA 4RNQA 3VJBA 3QQVA 5DZ2A 4KVWA 2ZCQA 2E4OA 1HXGA 4NFJF 5IMIA 3LVSA 3N3DA 3WSAA 3LK5A 3WJNA 5E8LA 2FORA 4ZQ8A 2ONGA 3V66A 4KQSA 4RXCA 3LGKA 4GAXA 2F8CF 4N1ZF 5IMPA 4GA3A 3VJEA 3RYWA 4OMGA 3Q2QA 4P0XA 5IK0A 3RMGA 4LA5A 5AYPA 2AZLA 3PKOA 3WEFA 3NRIA 3S4JA 3ICKA 3IPIA 3APZA 5HN9A 1YQ7A 5IMNA 5I1UA 3G4DA 5HNAA 3ICZA 2OPNA 4F6XA 2Z4YA 1JFAA 4MC0A 2E8XA 3Q1OA 5B03A 1V4EA 5DGNF 2E92A 1YYRA 3KROA 1N1ZA 4LFGA 3SDVA 5B0KA 1YYSA 1RQIA 4NFIF 1YYUA 2E94A 3ACYA 4E1EA 5DJRF 1WL2A 1UBVA 3N6KF 2AETA 1UBWA 5IKHA 5JV2F 3EGTA 3SDTA 2FTZA 1HM7A 3LEEA 3V1VA 1KIZA 4P0VA 1HXCA 3UCAA 4LXWA 5DJPF 3SDQA 3TFVA 3M02A 5ILJA 4H5DF 2J1PA 2QISA 3WCEA 3ZMCA 2PS4A 3ACXA 3V1XA 3WCMA 4RXAA 3LGZB 5JUZF 3OACB 5B02A 4LLTA 3N5HF 2PS5A 4DEMF 3WC9A 3LJIA 3N49F 5IL3A 3M0GA 2P1CA 2F94F 4L2XF 4NKFA 5ERMA 2F9KF 2ZEVA 3CKEA 5DHKA 1YHMA 5HN8A 3SDRA 4NG6A 3VJDA 1N1BA 3N1WF 1V4JA 3PH7A 5IN8A 3LG5A 4KQUA 3P5RA 2E8WA 4FP4A 3ID0A 1WMWA 3WEKA 4DHDA 2E8VA 2E95A 2E93A 5ILDA 3WJKA 3P8RA 2Q58A 3AE0A 5DJVF 4LOBA 1N22A 2OPMA 5CG6A 4Q23A 1RTRA 2O1OA 4LZ3A 4PVXF 2F7MF 2ZCRA 3N0GA 3PYBA 4LTZA 1WL0A 3DYHA 4KQ5A 3VJAA 3WCCA 3M9UA 3WCHA 1DGPA 2PS6A 4EA0A 4PVYF 4QXSF 3TFNA 2PS8A 3KRFB 4H5EF 2Z4ZA 2F8ZF 5A0JA 2Z4XA 3ACWA 3KRAA 1V4HA 1VG4A 4QPFA 4KVIA 3MZVA 3NPKA 4H5CF 5B01A 4JYXA 4KVDA 2PS7A 3WJOA 5EROA 2Z4WA 5IK6A 4GP2A 3LDWA 4NKEA 4N9UA 3KRCB 1JFGA 5B0JA 2ZEUA 2ZCSA 4LTVA 4EA1A 3MAVA 2E8TA 3PYAA 4KWDA 5EAUA 3KRPA 1VG7A 3VJCA 5B0MA 1YHKA 1V4IA 4KUXA 2ZY1A 3ICNA 5C05A 5AELA 1N20A 3DYFA 5A0KA 4DWBA 3LZ9A 1HM4A 3WSBA 5DGMF 3RBMA 3PDEA 3WEHA 3WEGA 2Z4VA 4DXJA 2J1OA 1HX9A 3B7LA 4RXEA 1PS1A 3OABA 3N0FA 1YJ4A 4OMHA 3VJ8A 5E8KA 5ER8A 5IVGA 1V4KA
chains in the Genus database with same CATH topology
3CP6A 2RAHA 3KRAB 2E91A 4DWGA 2ONHA 5DIQF 3Q30A 3Q2ZA 2Q80A 4XQTF 3WCBA 3WCDA 4XQSF 3ZCDA 4LUUA 2F89F 3AQ0A 2Q9YA 3KROB 4KPDA 3TC1A 3TFPA 2J5CA 3KRPB 3SAEA 4LA6A 4LFEA 5DW7A 5JV0F 2Z7HA 4LIXA 3SDUA 1DI1A 3WE9A 4GP1A 3M00A 5AHUB 5B00A 1VG2A 4LFVF 3W7FA 3EZ3A 3KB9A 5ERNA 3P41A 2OA6A 5H9DA 5ILZA 5CG5A 1WKZA 5ILYA 5ILHA 4K10A 3LSNA 4E9UA 5E8HA 2Z78A 4UMJA 3VJ9A 5ILKA 3TS7A 3BNYA 1UBXA 5KSXF 2I19A 4E9ZA 3N45F 3QKCA 5DGSF 4LPHF 3ZMBA 3P8LA 1VG3A 5EATA 4DZWA 5A0IA 3LMDA 1N23A 4LZ0A 3N5JF 1RQJA 4OKMA 5B0IA 3M01A 3CC9A 1ZW5A 5IL8A 4OKZA 3ADZA 5EASA 4P0WA 5IM1A 4RYPA 1EZFA 3S9VA 4EA2A 3BNXA 3OACA 4JXYA 2E8UA 4DI5A 1HXAA 3NF2A 4NFKF 3N46F 1YYQA 3DYGA 1KIYA 3WCAA 4KK2A 5JA0F 1WL1A 4HD1A 4RXDA 4XQRF 4JZXA 1N24A 4JVJF 5DHIA 5ILIA 5HN7A 3WCFA 3WCLA 2Z52A 3EFQA 4FJQA 2Z7IA 2AEKA 3ZL6A 3NPRA 3WCGA 4KVYA 3IBAA 4OGUA 4WK5A 5AFXA 2Q9ZA 1WL3A 4JXNA 3WCIA 2AZJA 3AQCB 5IK9A 1WY0A 3G4FA 2F92F 2ZCOA 3WCJA 3ASXA 3OYRA 4LZCA 4NUAA 3KBKA 2OGDA 1N21A 3WEIA 1YHLA 3LOMA 5IKAA 2VF6A 3RYEA 4F62A 2Z50A 4F6VA 3N3LF 3KRFA 3LLWA 4KPJA 2AZKA 1FPSA 1VG6A 4MC3A 3WEJA 3ICMA 4KFAA 2H8OA 3ZOUA 5B0LA 2DH4A 1YV5A 3KRCA 3OABB 3P5PA 1UBYA 4LLSA 4KKMA 2EWGA 1YYTA 2E90A 3AQBB 4MC8A 5JV1F 3N1VF 4LPGF 4JZBA 2AELA 4RNQA 3VJBA 3QQVA 5DZ2A 4KVWA 2ZCQA 2E4OA 1HXGA 4NFJF 5IMIA 3LVSA 3N3DA 3WSAA 3LK5A 3WJNA 5E8LA 2FORA 4ZQ8A 2ONGA 3V66A 4KQSA 4RXCA 3LGKA 4GAXA 2F8CF 4N1ZF 5IMPA 4GA3A 3VJEA 3RYWA 4OMGA 3Q2QA 4P0XA 5IK0A 3RMGA 4LA5A 5AYPA 2AZLA 3PKOA 3WEFA 3NRIA 3S4JA 3ICKA 3IPIA 3APZA 5HN9A 1YQ7A 5IMNA 5I1UA 3G4DA 5HNAA 3ICZA 2OPNA 4F6XA 2Z4YA 1JFAA 4MC0A 2E8XA 3Q1OA 5B03A 1V4EA 5DGNF 2E92A 1YYRA 3KROA 1N1ZA 4LFGA 3SDVA 5B0KA 1YYSA 1RQIA 4NFIF 1YYUA 2E94A 3ACYA 4E1EA 5DJRF 1WL2A 1UBVA 3N6KF 2AETA 1UBWA 5IKHA 5JV2F 3EGTA 3SDTA 2FTZA 1HM7A 3LEEA 3V1VA 1KIZA 4P0VA 1HXCA 3UCAA 4LXWA 5DJPF 3SDQA 3TFVA 3M02A 5ILJA 4H5DF 2J1PA 2QISA 3WCEA 3ZMCA 2PS4A 3ACXA 3V1XA 3WCMA 4RXAA 3LGZB 5JUZF 3OACB 5B02A 4LLTA 3N5HF 2PS5A 4DEMF 3WC9A 3LJIA 3N49F 5IL3A 3M0GA 2P1CA 2F94F 4L2XF 4NKFA 5ERMA 2F9KF 2ZEVA 3CKEA 5DHKA 1YHMA 5HN8A 3SDRA 4NG6A 3VJDA 1N1BA 3N1WF 1V4JA 3PH7A 5IN8A 3LG5A 4KQUA 3P5RA 2E8WA 4FP4A 3ID0A 1WMWA 3WEKA 4DHDA 2E8VA 2E95A 2E93A 5ILDA 3WJKA 3P8RA 2Q58A 3AE0A 5DJVF 4LOBA 1N22A 2OPMA 5CG6A 4Q23A 1RTRA 2O1OA 4LZ3A 4PVXF 2F7MF 2ZCRA 3N0GA 3PYBA 4LTZA 1WL0A 3DYHA 4KQ5A 3VJAA 3WCCA 3M9UA 3WCHA 1DGPA 2PS6A 4EA0A 4PVYF 4QXSF 3TFNA 2PS8A 3KRFB 4H5EF 2Z4ZA 2F8ZF 5A0JA 2Z4XA 3ACWA 3KRAA 1V4HA 1VG4A 4QPFA 4KVIA 3MZVA 3NPKA 4H5CF 5B01A 4JYXA 4KVDA 2PS7A 3WJOA 5EROA 2Z4WA 5IK6A 4GP2A 3LDWA 4NKEA 4N9UA 3KRCB 1JFGA 5B0JA 2ZEUA 2ZCSA 4LTVA 4EA1A 3MAVA 2E8TA 3PYAA 4KWDA 5EAUA 3KRPA 1VG7A 3VJCA 5B0MA 1YHKA 1V4IA 4KUXA 2ZY1A 3ICNA 5C05A 5AELA 1N20A 3DYFA 5A0KA 4DWBA 3LZ9A 1HM4A 3WSBA 5DGMF 3RBMA 3PDEA 3WEHA 3WEGA 2Z4VA 4DXJA 2J1OA 1HX9A 3B7LA 4RXEA 1PS1A 3OABA 3N0FA 1YJ4A 4OMHA 3VJ8A 5E8KA 5ER8A 5IVGA 1V4KA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3CP6 A;  2RAH A;  3KRA B;  2E91 A;  4DWG A;  2ONH A;  5DIQ F;  3Q30 A;  3Q2Z A;  2Q80 A;  4XQT F;  3WCB A;  3WCD A;  4XQS F;  3ZCD A;  4LUU A;  2F89 F;  3AQ0 A;  2Q9Y A;  3KRO B;  4KPD A;  3TC1 A;  3TFP A;  2J5C A;  3KRP B;  3SAE A;  4LA6 A;  4LFE A;  5DW7 A;  5JV0 F;  2Z7H A;  4LIX A;  3SDU A;  1DI1 A;  3WE9 A;  4GP1 A;  3M00 A;  5AHU B;  5B00 A;  1VG2 A;  4LFV F;  3W7F A;  3EZ3 A;  3KB9 A;  5ERN A;  3P41 A;  2OA6 A;  5H9D A;  5ILZ A;  5CG5 A;  1WKZ A;  5ILY A;  5ILH A;  4K10 A;  3LSN A;  4E9U A;  5E8H A;  2Z78 A;  4UMJ A;  3VJ9 A;  5ILK A;  3TS7 A;  3BNY A;  1UBX A;  5KSX F;  2I19 A;  4E9Z A;  3N45 F;  3QKC A;  5DGS F;  4LPH F;  3ZMB A;  3P8L A;  1VG3 A;  5EAT A;  4DZW A;  5A0I A;  3LMD A;  1N23 A;  4LZ0 A;  3N5J F;  1RQJ A;  4OKM A;  5B0I A;  3M01 A;  3CC9 A;  1ZW5 A;  5IL8 A;  4OKZ A;  3ADZ A;  5EAS A;  4P0W A;  5IM1 A;  4RYP A;  1EZF A;  3S9V A;  4EA2 A;  3BNX A;  3OAC A;  4JXY A;  2E8U A;  4DI5 A;  1HXA A;  3NF2 A;  4NFK F;  3N46 F;  1YYQ A;  3DYG A;  1KIY A;  3WCA A;  4KK2 A;  5JA0 F;  1WL1 A;  4HD1 A;  4RXD A;  4XQR F;  4JZX A;  1N24 A;  4JVJ F;  5DHI A;  5ILI A;  5HN7 A;  3WCF A;  3WCL A;  2Z52 A;  3EFQ A;  4FJQ A;  2Z7I A;  2AEK A;  3ZL6 A;  3NPR A;  3WCG A;  4KVY A;  3IBA A;  4OGU A;  4WK5 A;  5AFX A;  2Q9Z A;  1WL3 A;  4JXN A;  3WCI A;  2AZJ A;  3AQC B;  5IK9 A;  1WY0 A;  3G4F A;  2F92 F;  2ZCO A;  3WCJ A;  3ASX A;  3OYR A;  4LZC A;  4NUA A;  3KBK A;  2OGD A;  1N21 A;  3WEI A;  1YHL A;  3LOM A;  5IKA A;  2VF6 A;  3RYE A;  4F62 A;  2Z50 A;  4F6V A;  3N3L F;  3KRF A;  3LLW A;  4KPJ A;  2AZK A;  1FPS A;  1VG6 A;  4MC3 A;  3WEJ A;  3ICM A;  4KFA A;  2H8O A;  3ZOU A;  5B0L A;  2DH4 A;  1YV5 A;  3KRC A;  3OAB B;  3P5P A;  1UBY A;  4LLS A;  4KKM A;  2EWG A;  1YYT A;  2E90 A;  3AQB B;  4MC8 A;  5JV1 F;  3N1V F;  4LPG F;  4JZB A;  2AEL A;  4RNQ A;  3VJB A;  3QQV A;  5DZ2 A;  4KVW A;  2ZCQ A;  2E4O A;  1HXG A;  4NFJ F;  5IMI A;  3LVS A;  3N3D A;  3WSA A;  3LK5 A;  3WJN A;  5E8L A;  2FOR A;  4ZQ8 A;  2ONG A;  3V66 A;  4KQS A;  4RXC A;  3LGK A;  4GAX A;  2F8C F;  4N1Z F;  5IMP A;  4GA3 A;  3VJE A;  3RYW A;  4OMG A;  3Q2Q A;  4P0X A;  5IK0 A;  3RMG A;  4LA5 A;  5AYP A;  2AZL A;  3PKO A;  3WEF A;  3NRI A;  3S4J A;  3ICK A;  3IPI A;  3APZ A;  5HN9 A;  1YQ7 A;  5IMN A;  5I1U A;  3G4D A;  5HNA A;  3ICZ A;  2OPN A;  4F6X A;  2Z4Y A;  1JFA A;  4MC0 A;  2E8X A;  3Q1O A;  5B03 A;  1V4E A;  5DGN F;  2E92 A;  1YYR A;  3KRO A;  1N1Z A;  4LFG A;  3SDV A;  5B0K A;  1YYS A;  1RQI A;  4NFI F;  1YYU A;  2E94 A;  3ACY A;  4E1E A;  5DJR F;  1WL2 A;  1UBV A;  3N6K F;  2AET A;  1UBW A;  5IKH A;  5JV2 F;  3EGT A;  3SDT A;  2FTZ A;  1HM7 A;  3LEE A;  3V1V A;  1KIZ A;  4P0V A;  1HXC A;  3UCA A;  4LXW A;  5DJP F;  3SDQ A;  3TFV A;  3M02 A;  5ILJ A;  4H5D F;  2J1P A;  2QIS A;  3WCE A;  3ZMC A;  2PS4 A;  3ACX A;  3V1X A;  3WCM A;  4RXA A;  3LGZ B;  5JUZ F;  3OAC B;  5B02 A;  4LLT A;  3N5H F;  2PS5 A;  4DEM F;  3WC9 A;  3LJI A;  3N49 F;  5IL3 A;  3M0G A;  2P1C A;  2F94 F;  4L2X F;  4NKF A;  5ERM A;  2F9K F;  2ZEV A;  3CKE A;  5DHK A;  1YHM A;  5HN8 A;  3SDR A;  4NG6 A;  3VJD A;  1N1B A;  3N1W F;  1V4J A;  3PH7 A;  5IN8 A;  3LG5 A;  4KQU A;  3P5R A;  2E8W A;  4FP4 A;  3ID0 A;  1WMW A;  3WEK A;  4DHD A;  2E8V A;  2E95 A;  2E93 A;  5ILD A;  3WJK A;  3P8R A;  2Q58 A;  3AE0 A;  5DJV F;  4LOB A;  1N22 A;  2OPM A;  5CG6 A;  4Q23 A;  1RTR A;  2O1O A;  4LZ3 A;  4PVX F;  2F7M F;  2ZCR A;  3N0G A;  3PYB A;  4LTZ A;  1WL0 A;  3DYH A;  4KQ5 A;  3VJA A;  3WCC A;  3M9U A;  3WCH A;  1DGP A;  2PS6 A;  4EA0 A;  4PVY F;  4QXS F;  3TFN A;  2PS8 A;  3KRF B;  4H5E F;  2Z4Z A;  2F8Z F;  5A0J A;  2Z4X A;  3ACW A;  3KRA A;  1V4H A;  1VG4 A;  4QPF A;  4KVI A;  3MZV A;  3NPK A;  4H5C F;  5B01 A;  4JYX A;  4KVD A;  2PS7 A;  3WJO A;  5ERO A;  2Z4W A;  5IK6 A;  4GP2 A;  3LDW A;  4NKE A;  4N9U A;  3KRC B;  1JFG A;  5B0J A;  2ZEU A;  2ZCS A;  4LTV A;  4EA1 A;  3MAV A;  2E8T A;  3PYA A;  4KWD A;  5EAU A;  3KRP A;  1VG7 A;  3VJC A;  5B0M A;  1YHK A;  1V4I A;  4KUX A;  2ZY1 A;  3ICN A;  5C05 A;  5AEL A;  1N20 A;  3DYF A;  5A0K A;  4DWB A;  3LZ9 A;  1HM4 A;  3WSB A;  5DGM F;  3RBM A;  3PDE A;  3WEH A;  3WEG A;  2Z4V A;  4DXJ A;  2J1O A;  1HX9 A;  3B7L A;  4RXE A;  1PS1 A;  3OAB A;  3N0F A;  1YJ4 A;  4OMH A;  3VJ8 A;  5E8K A;  5ER8 A;  5IVG A;  1V4K A; 
#chains in the Genus database with same CATH topology
 3CP6 A;  2RAH A;  3KRA B;  2E91 A;  4DWG A;  2ONH A;  5DIQ F;  3Q30 A;  3Q2Z A;  2Q80 A;  4XQT F;  3WCB A;  3WCD A;  4XQS F;  3ZCD A;  4LUU A;  2F89 F;  3AQ0 A;  2Q9Y A;  3KRO B;  4KPD A;  3TC1 A;  3TFP A;  2J5C A;  3KRP B;  3SAE A;  4LA6 A;  4LFE A;  5DW7 A;  5JV0 F;  2Z7H A;  4LIX A;  3SDU A;  1DI1 A;  3WE9 A;  4GP1 A;  3M00 A;  5AHU B;  5B00 A;  1VG2 A;  4LFV F;  3W7F A;  3EZ3 A;  3KB9 A;  5ERN A;  3P41 A;  2OA6 A;  5H9D A;  5ILZ A;  5CG5 A;  1WKZ A;  5ILY A;  5ILH A;  4K10 A;  3LSN A;  4E9U A;  5E8H A;  2Z78 A;  4UMJ A;  3VJ9 A;  5ILK A;  3TS7 A;  3BNY A;  1UBX A;  5KSX F;  2I19 A;  4E9Z A;  3N45 F;  3QKC A;  5DGS F;  4LPH F;  3ZMB A;  3P8L A;  1VG3 A;  5EAT A;  4DZW A;  5A0I A;  3LMD A;  1N23 A;  4LZ0 A;  3N5J F;  1RQJ A;  4OKM A;  5B0I A;  3M01 A;  3CC9 A;  1ZW5 A;  5IL8 A;  4OKZ A;  3ADZ A;  5EAS A;  4P0W A;  5IM1 A;  4RYP A;  1EZF A;  3S9V A;  4EA2 A;  3BNX A;  3OAC A;  4JXY A;  2E8U A;  4DI5 A;  1HXA A;  3NF2 A;  4NFK F;  3N46 F;  1YYQ A;  3DYG A;  1KIY A;  3WCA A;  4KK2 A;  5JA0 F;  1WL1 A;  4HD1 A;  4RXD A;  4XQR F;  4JZX A;  1N24 A;  4JVJ F;  5DHI A;  5ILI A;  5HN7 A;  3WCF A;  3WCL A;  2Z52 A;  3EFQ A;  4FJQ A;  2Z7I A;  2AEK A;  3ZL6 A;  3NPR A;  3WCG A;  4KVY A;  3IBA A;  4OGU A;  4WK5 A;  5AFX A;  2Q9Z A;  1WL3 A;  4JXN A;  3WCI A;  2AZJ A;  3AQC B;  5IK9 A;  1WY0 A;  3G4F A;  2F92 F;  2ZCO A;  3WCJ A;  3ASX A;  3OYR A;  4LZC A;  4NUA A;  3KBK A;  2OGD A;  1N21 A;  3WEI A;  1YHL A;  3LOM A;  5IKA A;  2VF6 A;  3RYE A;  4F62 A;  2Z50 A;  4F6V A;  3N3L F;  3KRF A;  3LLW A;  4KPJ A;  2AZK A;  1FPS A;  1VG6 A;  4MC3 A;  3WEJ A;  3ICM A;  4KFA A;  2H8O A;  3ZOU A;  5B0L A;  2DH4 A;  1YV5 A;  3KRC A;  3OAB B;  3P5P A;  1UBY A;  4LLS A;  4KKM A;  2EWG A;  1YYT A;  2E90 A;  3AQB B;  4MC8 A;  5JV1 F;  3N1V F;  4LPG F;  4JZB A;  2AEL A;  4RNQ A;  3VJB A;  3QQV A;  5DZ2 A;  4KVW A;  2ZCQ A;  2E4O A;  1HXG A;  4NFJ F;  5IMI A;  3LVS A;  3N3D A;  3WSA A;  3LK5 A;  3WJN A;  5E8L A;  2FOR A;  4ZQ8 A;  2ONG A;  3V66 A;  4KQS A;  4RXC A;  3LGK A;  4GAX A;  2F8C F;  4N1Z F;  5IMP A;  4GA3 A;  3VJE A;  3RYW A;  4OMG A;  3Q2Q A;  4P0X A;  5IK0 A;  3RMG A;  4LA5 A;  5AYP A;  2AZL A;  3PKO A;  3WEF A;  3NRI A;  3S4J A;  3ICK A;  3IPI A;  3APZ A;  5HN9 A;  1YQ7 A;  5IMN A;  5I1U A;  3G4D A;  5HNA A;  3ICZ A;  2OPN A;  4F6X A;  2Z4Y A;  1JFA A;  4MC0 A;  2E8X A;  3Q1O A;  5B03 A;  1V4E A;  5DGN F;  2E92 A;  1YYR A;  3KRO A;  1N1Z A;  4LFG A;  3SDV A;  5B0K A;  1YYS A;  1RQI A;  4NFI F;  1YYU A;  2E94 A;  3ACY A;  4E1E A;  5DJR F;  1WL2 A;  1UBV A;  3N6K F;  2AET A;  1UBW A;  5IKH A;  5JV2 F;  3EGT A;  3SDT A;  2FTZ A;  1HM7 A;  3LEE A;  3V1V A;  1KIZ A;  4P0V A;  1HXC A;  3UCA A;  4LXW A;  5DJP F;  3SDQ A;  3TFV A;  3M02 A;  5ILJ A;  4H5D F;  2J1P A;  2QIS A;  3WCE A;  3ZMC A;  2PS4 A;  3ACX A;  3V1X A;  3WCM A;  4RXA A;  3LGZ B;  5JUZ F;  3OAC B;  5B02 A;  4LLT A;  3N5H F;  2PS5 A;  4DEM F;  3WC9 A;  3LJI A;  3N49 F;  5IL3 A;  3M0G A;  2P1C A;  2F94 F;  4L2X F;  4NKF A;  5ERM A;  2F9K F;  2ZEV A;  3CKE A;  5DHK A;  1YHM A;  5HN8 A;  3SDR A;  4NG6 A;  3VJD A;  1N1B A;  3N1W F;  1V4J A;  3PH7 A;  5IN8 A;  3LG5 A;  4KQU A;  3P5R A;  2E8W A;  4FP4 A;  3ID0 A;  1WMW A;  3WEK A;  4DHD A;  2E8V A;  2E95 A;  2E93 A;  5ILD A;  3WJK A;  3P8R A;  2Q58 A;  3AE0 A;  5DJV F;  4LOB A;  1N22 A;  2OPM A;  5CG6 A;  4Q23 A;  1RTR A;  2O1O A;  4LZ3 A;  4PVX F;  2F7M F;  2ZCR A;  3N0G A;  3PYB A;  4LTZ A;  1WL0 A;  3DYH A;  4KQ5 A;  3VJA A;  3WCC A;  3M9U A;  3WCH A;  1DGP A;  2PS6 A;  4EA0 A;  4PVY F;  4QXS F;  3TFN A;  2PS8 A;  3KRF B;  4H5E F;  2Z4Z A;  2F8Z F;  5A0J A;  2Z4X A;  3ACW A;  3KRA A;  1V4H A;  1VG4 A;  4QPF A;  4KVI A;  3MZV A;  3NPK A;  4H5C F;  5B01 A;  4JYX A;  4KVD A;  2PS7 A;  3WJO A;  5ERO A;  2Z4W A;  5IK6 A;  4GP2 A;  3LDW A;  4NKE A;  4N9U A;  3KRC B;  1JFG A;  5B0J A;  2ZEU A;  2ZCS A;  4LTV A;  4EA1 A;  3MAV A;  2E8T A;  3PYA A;  4KWD A;  5EAU A;  3KRP A;  1VG7 A;  3VJC A;  5B0M A;  1YHK A;  1V4I A;  4KUX A;  2ZY1 A;  3ICN A;  5C05 A;  5AEL A;  1N20 A;  3DYF A;  5A0K A;  4DWB A;  3LZ9 A;  1HM4 A;  3WSB A;  5DGM F;  3RBM A;  3PDE A;  3WEH A;  3WEG A;  2Z4V A;  4DXJ A;  2J1O A;  1HX9 A;  3B7L A;  4RXE A;  1PS1 A;  3OAB A;  3N0F A;  1YJ4 A;  4OMH A;  3VJ8 A;  5E8K A;  5ER8 A;  5IVG A;  1V4K A; 
#chains in the Genus database with same CATH homology
 3CP6 A;  2RAH A;  3KRA B;  2E91 A;  4DWG A;  2ONH A;  5DIQ F;  3Q30 A;  3Q2Z A;  2Q80 A;  4XQT F;  3WCB A;  3WCD A;  4XQS F;  3ZCD A;  4LUU A;  2F89 F;  3AQ0 A;  2Q9Y A;  3KRO B;  4KPD A;  3TC1 A;  3TFP A;  2J5C A;  3KRP B;  3SAE A;  4LA6 A;  4LFE A;  5DW7 A;  5JV0 F;  2Z7H A;  4LIX A;  3SDU A;  1DI1 A;  3WE9 A;  4GP1 A;  3M00 A;  5AHU B;  5B00 A;  1VG2 A;  4LFV F;  3W7F A;  3EZ3 A;  3KB9 A;  5ERN A;  3P41 A;  2OA6 A;  5H9D A;  5ILZ A;  5CG5 A;  1WKZ A;  5ILY A;  5ILH A;  4K10 A;  3LSN A;  4E9U A;  5E8H A;  2Z78 A;  4UMJ A;  3VJ9 A;  5ILK A;  3TS7 A;  3BNY A;  1UBX A;  5KSX F;  2I19 A;  4E9Z A;  3N45 F;  3QKC A;  5DGS F;  4LPH F;  3ZMB A;  3P8L A;  1VG3 A;  5EAT A;  4DZW A;  5A0I A;  3LMD A;  1N23 A;  4LZ0 A;  3N5J F;  1RQJ A;  4OKM A;  5B0I A;  3M01 A;  3CC9 A;  1ZW5 A;  5IL8 A;  4OKZ A;  3ADZ A;  5EAS A;  4P0W A;  5IM1 A;  4RYP A;  1EZF A;  3S9V A;  4EA2 A;  3BNX A;  3OAC A;  4JXY A;  2E8U A;  4DI5 A;  1HXA A;  3NF2 A;  4NFK F;  3N46 F;  1YYQ A;  3DYG A;  1KIY A;  3WCA A;  4KK2 A;  5JA0 F;  1WL1 A;  4HD1 A;  4RXD A;  4XQR F;  4JZX A;  1N24 A;  4JVJ F;  5DHI A;  5ILI A;  5HN7 A;  3WCF A;  3WCL A;  2Z52 A;  3EFQ A;  4FJQ A;  2Z7I A;  2AEK A;  3ZL6 A;  3NPR A;  3WCG A;  4KVY A;  3IBA A;  4OGU A;  4WK5 A;  5AFX A;  2Q9Z A;  1WL3 A;  4JXN A;  3WCI A;  2AZJ A;  3AQC B;  5IK9 A;  1WY0 A;  3G4F A;  2F92 F;  2ZCO A;  3WCJ A;  3ASX A;  3OYR A;  4LZC A;  4NUA A;  3KBK A;  2OGD A;  1N21 A;  3WEI A;  1YHL A;  3LOM A;  5IKA A;  2VF6 A;  3RYE A;  4F62 A;  2Z50 A;  4F6V A;  3N3L F;  3KRF A;  3LLW A;  4KPJ A;  2AZK A;  1FPS A;  1VG6 A;  4MC3 A;  3WEJ A;  3ICM A;  4KFA A;  2H8O A;  3ZOU A;  5B0L A;  2DH4 A;  1YV5 A;  3KRC A;  3OAB B;  3P5P A;  1UBY A;  4LLS A;  4KKM A;  2EWG A;  1YYT A;  2E90 A;  3AQB B;  4MC8 A;  5JV1 F;  3N1V F;  4LPG F;  4JZB A;  2AEL A;  4RNQ A;  3VJB A;  3QQV A;  5DZ2 A;  4KVW A;  2ZCQ A;  2E4O A;  1HXG A;  4NFJ F;  5IMI A;  3LVS A;  3N3D A;  3WSA A;  3LK5 A;  3WJN A;  5E8L A;  2FOR A;  4ZQ8 A;  2ONG A;  3V66 A;  4KQS A;  4RXC A;  3LGK A;  4GAX A;  2F8C F;  4N1Z F;  5IMP A;  4GA3 A;  3VJE A;  3RYW A;  4OMG A;  3Q2Q A;  4P0X A;  5IK0 A;  3RMG A;  4LA5 A;  5AYP A;  2AZL A;  3PKO A;  3WEF A;  3NRI A;  3S4J A;  3ICK A;  3IPI A;  3APZ A;  5HN9 A;  1YQ7 A;  5IMN A;  5I1U A;  3G4D A;  5HNA A;  3ICZ A;  2OPN A;  4F6X A;  2Z4Y A;  1JFA A;  4MC0 A;  2E8X A;  3Q1O A;  5B03 A;  1V4E A;  5DGN F;  2E92 A;  1YYR A;  3KRO A;  1N1Z A;  4LFG A;  3SDV A;  5B0K A;  1YYS A;  1RQI A;  4NFI F;  1YYU A;  2E94 A;  3ACY A;  4E1E A;  5DJR F;  1WL2 A;  1UBV A;  3N6K F;  2AET A;  1UBW A;  5IKH A;  5JV2 F;  3EGT A;  3SDT A;  2FTZ A;  1HM7 A;  3LEE A;  3V1V A;  1KIZ A;  4P0V A;  1HXC A;  3UCA A;  4LXW A;  5DJP F;  3SDQ A;  3TFV A;  3M02 A;  5ILJ A;  4H5D F;  2J1P A;  2QIS A;  3WCE A;  3ZMC A;  2PS4 A;  3ACX A;  3V1X A;  3WCM A;  4RXA A;  3LGZ B;  5JUZ F;  3OAC B;  5B02 A;  4LLT A;  3N5H F;  2PS5 A;  4DEM F;  3WC9 A;  3LJI A;  3N49 F;  5IL3 A;  3M0G A;  2P1C A;  2F94 F;  4L2X F;  4NKF A;  5ERM A;  2F9K F;  2ZEV A;  3CKE A;  5DHK A;  1YHM A;  5HN8 A;  3SDR A;  4NG6 A;  3VJD A;  1N1B A;  3N1W F;  1V4J A;  3PH7 A;  5IN8 A;  3LG5 A;  4KQU A;  3P5R A;  2E8W A;  4FP4 A;  3ID0 A;  1WMW A;  3WEK A;  4DHD A;  2E8V A;  2E95 A;  2E93 A;  5ILD A;  3WJK A;  3P8R A;  2Q58 A;  3AE0 A;  5DJV F;  4LOB A;  1N22 A;  2OPM A;  5CG6 A;  4Q23 A;  1RTR A;  2O1O A;  4LZ3 A;  4PVX F;  2F7M F;  2ZCR A;  3N0G A;  3PYB A;  4LTZ A;  1WL0 A;  3DYH A;  4KQ5 A;  3VJA A;  3WCC A;  3M9U A;  3WCH A;  1DGP A;  2PS6 A;  4EA0 A;  4PVY F;  4QXS F;  3TFN A;  2PS8 A;  3KRF B;  4H5E F;  2Z4Z A;  2F8Z F;  5A0J A;  2Z4X A;  3ACW A;  3KRA A;  1V4H A;  1VG4 A;  4QPF A;  4KVI A;  3MZV A;  3NPK A;  4H5C F;  5B01 A;  4JYX A;  4KVD A;  2PS7 A;  3WJO A;  5ERO A;  2Z4W A;  5IK6 A;  4GP2 A;  3LDW A;  4NKE A;  4N9U A;  3KRC B;  1JFG A;  5B0J A;  2ZEU A;  2ZCS A;  4LTV A;  4EA1 A;  3MAV A;  2E8T A;  3PYA A;  4KWD A;  5EAU A;  3KRP A;  1VG7 A;  3VJC A;  5B0M A;  1YHK A;  1V4I A;  4KUX A;  2ZY1 A;  3ICN A;  5C05 A;  5AEL A;  1N20 A;  3DYF A;  5A0K A;  4DWB A;  3LZ9 A;  1HM4 A;  3WSB A;  5DGM F;  3RBM A;  3PDE A;  3WEH A;  3WEG A;  2Z4V A;  4DXJ A;  2J1O A;  1HX9 A;  3B7L A;  4RXE A;  1PS1 A;  3OAB A;  3N0F A;  1YJ4 A;  4OMH A;  3VJ8 A;  5E8K A;  5ER8 A;  5IVG A;  1V4K A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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