1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase
source organism Trypanosoma cruzi
publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
molecule keywords farnesyl pyrophosphate synthase
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
2AETA 3SDUA 5EROA 3SDRA 3LJIA 4ZQ8A 3WE9A 3ACYA 5B00A 2Z50A 2ZCSA 3M0GA 4KQ5A 4JZXA 4NFIF 5DJPF 3EZ3A 2Q80A 4NUAA 2E8WA 2PS5A 1N24A 3N6KF 4KKMA 4MC0A 4XQRF 4KPDA 3ICNA 1HM7A 4KVWA 4KQSA 1JFGA 3SDVA 2ZEVA 4MC3A 4UMJA 1HM4A 3LG5A 5EATA 2PS6A 3QQVA 4N1ZF 3WCMA 4EA0A 1DGPA 4N9UA 5E8KA 1YHKA 3AQ0A 5IL3A 4LIXA 4PVYF 3PYAA 5B0KA 1YV5A 2OPNA 4OGUA 5ERNA 2VF6A 4JXNA 2AELA 4P0WA 5B03A 5I1UA 1WL1A 5CG6A 5ILJA 4LLTA 4OMGA 4XQSF 4LFEA 3WEGA 4NFKF 4LZ3A 5JV2F 3SDQA 4KK2A 5C05A 3WSBA 5DHKA 4OKZA 2AZJA 2E8TA 2ZY1A 5HN7A 3KROA 4MC8A 2F89F 5A0JA 3WEIA 3KRCB 5DW7A 3IPIA 3M00A 4NKFA 5IL8A 3WCCA 5HN8A 4RXCA 2F8CF 3NF2A 5B01A 4LA5A 3N46F 3MZVA 3WCJA 5H9DA 3OABB 4P0XA 3EFQA 4KQUA 1V4HA 3N0FA 3ZL6A 2P1CA 4QXSF 2E8VA 3OACB 5IMPA 3KRFB 1RQIA 5IKAA 5DIQF 3ICKA 3N3LF 3AQBB 3WCHA 2ONHA 1JFAA 3N5HF 5DGSF 2ZCRA 5ILZA 3DYGA 1V4KA 2PS4A 4RNQA 2E91A 3CC9A 4DEMF 3P5PA 4E9ZA 5DGNF 2OA6A 4DI5A 3LDWA 5A0KA 3WJNA 1HXAA 3M01A 1YJ4A 2AZLA 4RXDA 4LUUA 3WJOA 4F6VA 1N23A 3P5RA 3NPKA 5AELA 3VJ9A 1V4EA 2H8OA 4NFJF 4DWGA 2Q9ZA 5B0JA 2E95A 1KIZA 4KFAA 5B0MA 2Z4VA 3LLWA 2PS8A 3KRAA 5DZ2A 4FP4A 4KUXA 3OYRA 2DH4A 1YYUA 2Q9YA 1WL2A 4LLSA 2Z4WA 5ILYA 4K10A 3NPRA 3N45F 4LTZA 2AZKA 4LZ0A 4XQTF 1YYQA 4RYPA 5E8HA 3S4JA 1PS1A 1EZFA 3N5JF 5IMNA 1WKZA 1WMWA 4DWBA 3P8LA 1YYSA 4GP1A 2Z4XA 1VG7A 2Z4ZA 3ZCDA 3SAEA 3ACWA 2Z78A 2ZEUA 5ILDA 5ERMA 3TS7A 5B0IA 3APZA 3WCDA 5B02A 5AFXA 3SDTA 3CKEA 3S9VA 2E90A 3VJDA 2FORA 4EA1A 1V4JA 3KBKA 2EWGA 2OGDA 5DJRF 3N1WF 1RQJA 5DHIA 4GA3A 3KRPA 4Q23A 3ASXA 3G4DA 3Q2ZA 3WCIA 3Q30A 3WSAA 1HX9A 2ZCQA 5JUZF 3N3DA 3WCFA 4OMHA 1YHLA 5IK0A 3WJKA 1ZW5A 3LGZB 5IMIA 4LZCA 1WL0A 1HXCA 4H5EF 1UBXA 3ZMCA 1UBVA 2I19A 5JV0F 4WK5A 4KVDA 1UBWA 1VG4A 3KROB 2F92F 3LEEA 4QPFA 4H5DF 2ONGA 1N22A 3VJCA 3DYFA 5ILKA 3UCAA 3LGKA 5JA0F 3WCAA 4LA6A 4KPJA 3KB9A 2O1OA 3TFVA 3TFNA 3M02A 5ILHA 3WCGA 1YQ7A 3ICZA 5IKHA 1HXGA 3EGTA 2J1OA 3DYHA 3BNXA 3WCBA 1V4IA 4FJQA 3ACXA 4DXJA 3ZMBA 4OKMA 3B7LA 4KWDA 3LZ9A 3V1VA 3N0GA 3BNYA 5ER8A 1N21A 4GAXA 3Q2QA 3WEHA 4NG6A 2E8XA 1VG3A 5B0LA 3ZOUA 5DJVF 3QKCA 3LMDA 3N49F 4GP2A 1YYTA 2AEKA 1N20A 4NKEA 4RXAA 4LPHF 5AYPA 4JVJF 2Z52A 3KRCA 5JV1F 4JYXA 4LOBA 5IK6A 5IVGA 4DZWA 5CG5A 5HN9A 1YHMA 2OPMA 5HNAA 4LFGA 5IN8A 3PYBA 3G4FA 2E8UA 3CP6A 3KRAB 1VG2A 3OABA 3AE0A 3AQCB 2Z7IA 4JXYA 1WL3A 2Z7HA 2Z4YA 3WCLA 3RMGA 5EASA 3RYWA 4E1EA 4KVYA 3OACA 2FTZA 5IK9A 2F9KF 3KRFA 2RAHA 4DHDA 1KIYA 5IM1A 3M9UA 4LPGF 3VJAA 2E4OA 3Q1OA 3LK5A 4LTVA 2PS7A 3LVSA 3RYEA 3WEFA 5AHUB 3TFPA 2F94F 3ADZA 4RXEA 1RTRA 3WEKA 3LOMA 5EAUA 3PKOA 3P41A 3W7FA 2F8ZF 5A0IA 4F62A 3WEJA 2E94A 5DGMF 3TC1A 1DI1A 2J1PA 1N1BA 1WY0A 3IBAA 4KVIA 4PVXF 3P8RA 3ID0A 3PH7A 4HD1A 3VJBA 4H5CF 3NRIA 5ILIA 5KSXF 1YYRA 4EA2A 3LSNA 3ICMA 4L2XF 2E92A 3KRPB 2QISA 3N1VF 3V66A 4LXWA 2F7MF 3MAVA 3VJ8A 1UBYA 3VJEA 1FPSA 2E93A 3PDEA 2J5CA 3RBMA 4E9UA 4JZBA 4P0VA 2ZCOA 2Q58A 4F6XA 3V1XA 3WCEA 5E8LA 4LFVF 1VG6A 1N1ZA 3WC9A
chains in the Genus database with same CATH superfamily
2AETA 3SDUA 5EROA 3SDRA 3LJIA 4ZQ8A 3WE9A 3ACYA 5B00A 2Z50A 2ZCSA 3M0GA 4KQ5A 4JZXA 4NFIF 5DJPF 3EZ3A 2Q80A 4NUAA 2E8WA 2PS5A 1N24A 3N6KF 4KKMA 4MC0A 4XQRF 4KPDA 3ICNA 1HM7A 4KVWA 4KQSA 1JFGA 3SDVA 2ZEVA 4MC3A 4UMJA 1HM4A 3LG5A 5EATA 2PS6A 3QQVA 4N1ZF 3WCMA 4EA0A 1DGPA 4N9UA 5E8KA 1YHKA 3AQ0A 5IL3A 4LIXA 4PVYF 3PYAA 5B0KA 1YV5A 2OPNA 4OGUA 5ERNA 2VF6A 4JXNA 2AELA 4P0WA 5B03A 5I1UA 1WL1A 5CG6A 5ILJA 4LLTA 4OMGA 4XQSF 4LFEA 3WEGA 4NFKF 4LZ3A 5JV2F 3SDQA 4KK2A 5C05A 3WSBA 5DHKA 4OKZA 2AZJA 2E8TA 2ZY1A 5HN7A 3KROA 4MC8A 2F89F 5A0JA 3WEIA 3KRCB 5DW7A 3IPIA 3M00A 4NKFA 5IL8A 3WCCA 5HN8A 4RXCA 2F8CF 3NF2A 5B01A 4LA5A 3N46F 3MZVA 3WCJA 5H9DA 3OABB 4P0XA 3EFQA 4KQUA 1V4HA 3N0FA 3ZL6A 2P1CA 4QXSF 2E8VA 3OACB 5IMPA 3KRFB 1RQIA 5IKAA 5DIQF 3ICKA 3N3LF 3AQBB 3WCHA 2ONHA 1JFAA 3N5HF 5DGSF 2ZCRA 5ILZA 3DYGA 1V4KA 2PS4A 4RNQA 2E91A 3CC9A 4DEMF 3P5PA 4E9ZA 5DGNF 2OA6A 4DI5A 3LDWA 5A0KA 3WJNA 1HXAA 3M01A 1YJ4A 2AZLA 4RXDA 4LUUA 3WJOA 4F6VA 1N23A 3P5RA 3NPKA 5AELA 3VJ9A 1V4EA 2H8OA 4NFJF 4DWGA 2Q9ZA 5B0JA 2E95A 1KIZA 4KFAA 5B0MA 2Z4VA 3LLWA 2PS8A 3KRAA 5DZ2A 4FP4A 4KUXA 3OYRA 2DH4A 1YYUA 2Q9YA 1WL2A 4LLSA 2Z4WA 5ILYA 4K10A 3NPRA 3N45F 4LTZA 2AZKA 4LZ0A 4XQTF 1YYQA 4RYPA 5E8HA 3S4JA 1PS1A 1EZFA 3N5JF 5IMNA 1WKZA 1WMWA 4DWBA 3P8LA 1YYSA 4GP1A 2Z4XA 1VG7A 2Z4ZA 3ZCDA 3SAEA 3ACWA 2Z78A 2ZEUA 5ILDA 5ERMA 3TS7A 5B0IA 3APZA 3WCDA 5B02A 5AFXA 3SDTA 3CKEA 3S9VA 2E90A 3VJDA 2FORA 4EA1A 1V4JA 3KBKA 2EWGA 2OGDA 5DJRF 3N1WF 1RQJA 5DHIA 4GA3A 3KRPA 4Q23A 3ASXA 3G4DA 3Q2ZA 3WCIA 3Q30A 3WSAA 1HX9A 2ZCQA 5JUZF 3N3DA 3WCFA 4OMHA 1YHLA 5IK0A 3WJKA 1ZW5A 3LGZB 5IMIA 4LZCA 1WL0A 1HXCA 4H5EF 1UBXA 3ZMCA 1UBVA 2I19A 5JV0F 4WK5A 4KVDA 1UBWA 1VG4A 3KROB 2F92F 3LEEA 4QPFA 4H5DF 2ONGA 1N22A 3VJCA 3DYFA 5ILKA 3UCAA 3LGKA 5JA0F 3WCAA 4LA6A 4KPJA 3KB9A 2O1OA 3TFVA 3TFNA 3M02A 5ILHA 3WCGA 1YQ7A 3ICZA 5IKHA 1HXGA 3EGTA 2J1OA 3DYHA 3BNXA 3WCBA 1V4IA 4FJQA 3ACXA 4DXJA 3ZMBA 4OKMA 3B7LA 4KWDA 3LZ9A 3V1VA 3N0GA 3BNYA 5ER8A 1N21A 4GAXA 3Q2QA 3WEHA 4NG6A 2E8XA 1VG3A 5B0LA 3ZOUA 5DJVF 3QKCA 3LMDA 3N49F 4GP2A 1YYTA 2AEKA 1N20A 4NKEA 4RXAA 4LPHF 5AYPA 4JVJF 2Z52A 3KRCA 5JV1F 4JYXA 4LOBA 5IK6A 5IVGA 4DZWA 5CG5A 5HN9A 1YHMA 2OPMA 5HNAA 4LFGA 5IN8A 3PYBA 3G4FA 2E8UA 3CP6A 3KRAB 1VG2A 3OABA 3AE0A 3AQCB 2Z7IA 4JXYA 1WL3A 2Z7HA 2Z4YA 3WCLA 3RMGA 5EASA 3RYWA 4E1EA 4KVYA 3OACA 2FTZA 5IK9A 2F9KF 3KRFA 2RAHA 4DHDA 1KIYA 5IM1A 3M9UA 4LPGF 3VJAA 2E4OA 3Q1OA 3LK5A 4LTVA 2PS7A 3LVSA 3RYEA 3WEFA 5AHUB 3TFPA 2F94F 3ADZA 4RXEA 1RTRA 3WEKA 3LOMA 5EAUA 3PKOA 3P41A 3W7FA 2F8ZF 5A0IA 4F62A 3WEJA 2E94A 5DGMF 3TC1A 1DI1A 2J1PA 1N1BA 1WY0A 3IBAA 4KVIA 4PVXF 3P8RA 3ID0A 3PH7A 4HD1A 3VJBA 4H5CF 3NRIA 5ILIA 5KSXF 1YYRA 4EA2A 3LSNA 3ICMA 4L2XF 2E92A 3KRPB 2QISA 3N1VF 3V66A 4LXWA 2F7MF 3MAVA 3VJ8A 1UBYA 3VJEA 1FPSA 2E93A 3PDEA 2J5CA 3RBMA 4E9UA 4JZBA 4P0VA 2ZCOA 2Q58A 4F6XA 3V1XA 3WCEA 5E8LA 4LFVF 1VG6A 1N1ZA 3WC9A
chains in the Genus database with same CATH topology
2AETA 3SDUA 5EROA 3SDRA 3LJIA 4ZQ8A 3WE9A 3ACYA 5B00A 2Z50A 2ZCSA 3M0GA 4KQ5A 4JZXA 4NFIF 5DJPF 3EZ3A 2Q80A 4NUAA 2E8WA 2PS5A 1N24A 3N6KF 4KKMA 4MC0A 4XQRF 4KPDA 3ICNA 1HM7A 4KVWA 4KQSA 1JFGA 3SDVA 2ZEVA 4MC3A 4UMJA 1HM4A 3LG5A 5EATA 2PS6A 3QQVA 4N1ZF 3WCMA 4EA0A 1DGPA 4N9UA 5E8KA 1YHKA 3AQ0A 5IL3A 4LIXA 4PVYF 3PYAA 5B0KA 1YV5A 2OPNA 4OGUA 5ERNA 2VF6A 4JXNA 2AELA 4P0WA 5B03A 5I1UA 1WL1A 5CG6A 5ILJA 4LLTA 4OMGA 4XQSF 4LFEA 3WEGA 4NFKF 4LZ3A 5JV2F 3SDQA 4KK2A 5C05A 3WSBA 5DHKA 4OKZA 2AZJA 2E8TA 2ZY1A 5HN7A 3KROA 4MC8A 2F89F 5A0JA 3WEIA 3KRCB 5DW7A 3IPIA 3M00A 4NKFA 5IL8A 3WCCA 5HN8A 4RXCA 2F8CF 3NF2A 5B01A 4LA5A 3N46F 3MZVA 3WCJA 5H9DA 3OABB 4P0XA 3EFQA 4KQUA 1V4HA 3N0FA 3ZL6A 2P1CA 4QXSF 2E8VA 3OACB 5IMPA 3KRFB 1RQIA 5IKAA 5DIQF 3ICKA 3N3LF 3AQBB 3WCHA 2ONHA 1JFAA 3N5HF 5DGSF 2ZCRA 5ILZA 3DYGA 1V4KA 2PS4A 4RNQA 2E91A 3CC9A 4DEMF 3P5PA 4E9ZA 5DGNF 2OA6A 4DI5A 3LDWA 5A0KA 3WJNA 1HXAA 3M01A 1YJ4A 2AZLA 4RXDA 4LUUA 3WJOA 4F6VA 1N23A 3P5RA 3NPKA 5AELA 3VJ9A 1V4EA 2H8OA 4NFJF 4DWGA 2Q9ZA 5B0JA 2E95A 1KIZA 4KFAA 5B0MA 2Z4VA 3LLWA 2PS8A 3KRAA 5DZ2A 4FP4A 4KUXA 3OYRA 2DH4A 1YYUA 2Q9YA 1WL2A 4LLSA 2Z4WA 5ILYA 4K10A 3NPRA 3N45F 4LTZA 2AZKA 4LZ0A 4XQTF 1YYQA 4RYPA 5E8HA 3S4JA 1PS1A 1EZFA 3N5JF 5IMNA 1WKZA 1WMWA 4DWBA 3P8LA 1YYSA 4GP1A 2Z4XA 1VG7A 2Z4ZA 3ZCDA 3SAEA 3ACWA 2Z78A 2ZEUA 5ILDA 5ERMA 3TS7A 5B0IA 3APZA 3WCDA 5B02A 5AFXA 3SDTA 3CKEA 3S9VA 2E90A 3VJDA 2FORA 4EA1A 1V4JA 3KBKA 2EWGA 2OGDA 5DJRF 3N1WF 1RQJA 5DHIA 4GA3A 3KRPA 4Q23A 3ASXA 3G4DA 3Q2ZA 3WCIA 3Q30A 3WSAA 1HX9A 2ZCQA 5JUZF 3N3DA 3WCFA 4OMHA 1YHLA 5IK0A 3WJKA 1ZW5A 3LGZB 5IMIA 4LZCA 1WL0A 1HXCA 4H5EF 1UBXA 3ZMCA 1UBVA 2I19A 5JV0F 4WK5A 4KVDA 1UBWA 1VG4A 3KROB 2F92F 3LEEA 4QPFA 4H5DF 2ONGA 1N22A 3VJCA 3DYFA 5ILKA 3UCAA 3LGKA 5JA0F 3WCAA 4LA6A 4KPJA 3KB9A 2O1OA 3TFVA 3TFNA 3M02A 5ILHA 3WCGA 1YQ7A 3ICZA 5IKHA 1HXGA 3EGTA 2J1OA 3DYHA 3BNXA 3WCBA 1V4IA 4FJQA 3ACXA 4DXJA 3ZMBA 4OKMA 3B7LA 4KWDA 3LZ9A 3V1VA 3N0GA 3BNYA 5ER8A 1N21A 4GAXA 3Q2QA 3WEHA 4NG6A 2E8XA 1VG3A 5B0LA 3ZOUA 5DJVF 3QKCA 3LMDA 3N49F 4GP2A 1YYTA 2AEKA 1N20A 4NKEA 4RXAA 4LPHF 5AYPA 4JVJF 2Z52A 3KRCA 5JV1F 4JYXA 4LOBA 5IK6A 5IVGA 4DZWA 5CG5A 5HN9A 1YHMA 2OPMA 5HNAA 4LFGA 5IN8A 3PYBA 3G4FA 2E8UA 3CP6A 3KRAB 1VG2A 3OABA 3AE0A 3AQCB 2Z7IA 4JXYA 1WL3A 2Z7HA 2Z4YA 3WCLA 3RMGA 5EASA 3RYWA 4E1EA 4KVYA 3OACA 2FTZA 5IK9A 2F9KF 3KRFA 2RAHA 4DHDA 1KIYA 5IM1A 3M9UA 4LPGF 3VJAA 2E4OA 3Q1OA 3LK5A 4LTVA 2PS7A 3LVSA 3RYEA 3WEFA 5AHUB 3TFPA 2F94F 3ADZA 4RXEA 1RTRA 3WEKA 3LOMA 5EAUA 3PKOA 3P41A 3W7FA 2F8ZF 5A0IA 4F62A 3WEJA 2E94A 5DGMF 3TC1A 1DI1A 2J1PA 1N1BA 1WY0A 3IBAA 4KVIA 4PVXF 3P8RA 3ID0A 3PH7A 4HD1A 3VJBA 4H5CF 3NRIA 5ILIA 5KSXF 1YYRA 4EA2A 3LSNA 3ICMA 4L2XF 2E92A 3KRPB 2QISA 3N1VF 3V66A 4LXWA 2F7MF 3MAVA 3VJ8A 1UBYA 3VJEA 1FPSA 2E93A 3PDEA 2J5CA 3RBMA 4E9UA 4JZBA 4P0VA 2ZCOA 2Q58A 4F6XA 3V1XA 3WCEA 5E8LA 4LFVF 1VG6A 1N1ZA 3WC9A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2AET A;  3SDU A;  5ERO A;  3SDR A;  3LJI A;  4ZQ8 A;  3WE9 A;  3ACY A;  5B00 A;  2Z50 A;  2ZCS A;  3M0G A;  4KQ5 A;  4JZX A;  4NFI F;  5DJP F;  3EZ3 A;  2Q80 A;  4NUA A;  2E8W A;  2PS5 A;  1N24 A;  3N6K F;  4KKM A;  4MC0 A;  4XQR F;  4KPD A;  3ICN A;  1HM7 A;  4KVW A;  4KQS A;  1JFG A;  3SDV A;  2ZEV A;  4MC3 A;  4UMJ A;  1HM4 A;  3LG5 A;  5EAT A;  2PS6 A;  3QQV A;  4N1Z F;  3WCM A;  4EA0 A;  1DGP A;  4N9U A;  5E8K A;  1YHK A;  3AQ0 A;  5IL3 A;  4LIX A;  4PVY F;  3PYA A;  5B0K A;  1YV5 A;  2OPN A;  4OGU A;  5ERN A;  2VF6 A;  4JXN A;  2AEL A;  4P0W A;  5B03 A;  5I1U A;  1WL1 A;  5CG6 A;  5ILJ A;  4LLT A;  4OMG A;  4XQS F;  4LFE A;  3WEG A;  4NFK F;  4LZ3 A;  5JV2 F;  3SDQ A;  4KK2 A;  5C05 A;  3WSB A;  5DHK A;  4OKZ A;  2AZJ A;  2E8T A;  2ZY1 A;  5HN7 A;  3KRO A;  4MC8 A;  2F89 F;  5A0J A;  3WEI A;  3KRC B;  5DW7 A;  3IPI A;  3M00 A;  4NKF A;  5IL8 A;  3WCC A;  5HN8 A;  4RXC A;  2F8C F;  3NF2 A;  5B01 A;  4LA5 A;  3N46 F;  3MZV A;  3WCJ A;  5H9D A;  3OAB B;  4P0X A;  3EFQ A;  4KQU A;  1V4H A;  3N0F A;  3ZL6 A;  2P1C A;  4QXS F;  2E8V A;  3OAC B;  5IMP A;  3KRF B;  1RQI A;  5IKA A;  5DIQ F;  3ICK A;  3N3L F;  3AQB B;  3WCH A;  2ONH A;  1JFA A;  3N5H F;  5DGS F;  2ZCR A;  5ILZ A;  3DYG A;  1V4K A;  2PS4 A;  4RNQ A;  2E91 A;  3CC9 A;  4DEM F;  3P5P A;  4E9Z A;  5DGN F;  2OA6 A;  4DI5 A;  3LDW A;  5A0K A;  3WJN A;  1HXA A;  3M01 A;  1YJ4 A;  2AZL A;  4RXD A;  4LUU A;  3WJO A;  4F6V A;  1N23 A;  3P5R A;  3NPK A;  5AEL A;  3VJ9 A;  1V4E A;  2H8O A;  4NFJ F;  4DWG A;  2Q9Z A;  5B0J A;  2E95 A;  1KIZ A;  4KFA A;  5B0M A;  2Z4V A;  3LLW A;  2PS8 A;  3KRA A;  5DZ2 A;  4FP4 A;  4KUX A;  3OYR A;  2DH4 A;  1YYU A;  2Q9Y A;  1WL2 A;  4LLS A;  2Z4W A;  5ILY A;  4K10 A;  3NPR A;  3N45 F;  4LTZ A;  2AZK A;  4LZ0 A;  4XQT F;  1YYQ A;  4RYP A;  5E8H A;  3S4J A;  1PS1 A;  1EZF A;  3N5J F;  5IMN A;  1WKZ A;  1WMW A;  4DWB A;  3P8L A;  1YYS A;  4GP1 A;  2Z4X A;  1VG7 A;  2Z4Z A;  3ZCD A;  3SAE A;  3ACW A;  2Z78 A;  2ZEU A;  5ILD A;  5ERM A;  3TS7 A;  5B0I A;  3APZ A;  3WCD A;  5B02 A;  5AFX A;  3SDT A;  3CKE A;  3S9V A;  2E90 A;  3VJD A;  2FOR A;  4EA1 A;  1V4J A;  3KBK A;  2EWG A;  2OGD A;  5DJR F;  3N1W F;  1RQJ A;  5DHI A;  4GA3 A;  3KRP A;  4Q23 A;  3ASX A;  3G4D A;  3Q2Z A;  3WCI A;  3Q30 A;  3WSA A;  1HX9 A;  2ZCQ A;  5JUZ F;  3N3D A;  3WCF A;  4OMH A;  1YHL A;  5IK0 A;  3WJK A;  1ZW5 A;  3LGZ B;  5IMI A;  4LZC A;  1WL0 A;  1HXC A;  4H5E F;  1UBX A;  3ZMC A;  1UBV A;  2I19 A;  5JV0 F;  4WK5 A;  4KVD A;  1UBW A;  1VG4 A;  3KRO B;  2F92 F;  3LEE A;  4QPF A;  4H5D F;  2ONG A;  1N22 A;  3VJC A;  3DYF A;  5ILK A;  3UCA A;  3LGK A;  5JA0 F;  3WCA A;  4LA6 A;  4KPJ A;  3KB9 A;  2O1O A;  3TFV A;  3TFN A;  3M02 A;  5ILH A;  3WCG A;  1YQ7 A;  3ICZ A;  5IKH A;  1HXG A;  3EGT A;  2J1O A;  3DYH A;  3BNX A;  3WCB A;  1V4I A;  4FJQ A;  3ACX A;  4DXJ A;  3ZMB A;  4OKM A;  3B7L A;  4KWD A;  3LZ9 A;  3V1V A;  3N0G A;  3BNY A;  5ER8 A;  1N21 A;  4GAX A;  3Q2Q A;  3WEH A;  4NG6 A;  2E8X A;  1VG3 A;  5B0L A;  3ZOU A;  5DJV F;  3QKC A;  3LMD A;  3N49 F;  4GP2 A;  1YYT A;  2AEK A;  1N20 A;  4NKE A;  4RXA A;  4LPH F;  5AYP A;  4JVJ F;  2Z52 A;  3KRC A;  5JV1 F;  4JYX A;  4LOB A;  5IK6 A;  5IVG A;  4DZW A;  5CG5 A;  5HN9 A;  1YHM A;  2OPM A;  5HNA A;  4LFG A;  5IN8 A;  3PYB A;  3G4F A;  2E8U A;  3CP6 A;  3KRA B;  1VG2 A;  3OAB A;  3AE0 A;  3AQC B;  2Z7I A;  4JXY A;  1WL3 A;  2Z7H A;  2Z4Y A;  3WCL A;  3RMG A;  5EAS A;  3RYW A;  4E1E A;  4KVY A;  3OAC A;  2FTZ A;  5IK9 A;  2F9K F;  3KRF A;  2RAH A;  4DHD A;  1KIY A;  5IM1 A;  3M9U A;  4LPG F;  3VJA A;  2E4O A;  3Q1O A;  3LK5 A;  4LTV A;  2PS7 A;  3LVS A;  3RYE A;  3WEF A;  5AHU B;  3TFP A;  2F94 F;  3ADZ A;  4RXE A;  1RTR A;  3WEK A;  3LOM A;  5EAU A;  3PKO A;  3P41 A;  3W7F A;  2F8Z F;  5A0I A;  4F62 A;  3WEJ A;  2E94 A;  5DGM F;  3TC1 A;  1DI1 A;  2J1P A;  1N1B A;  1WY0 A;  3IBA A;  4KVI A;  4PVX F;  3P8R A;  3ID0 A;  3PH7 A;  4HD1 A;  3VJB A;  4H5C F;  3NRI A;  5ILI A;  5KSX F;  1YYR A;  4EA2 A;  3LSN A;  3ICM A;  4L2X F;  2E92 A;  3KRP B;  2QIS A;  3N1V F;  3V66 A;  4LXW A;  2F7M F;  3MAV A;  3VJ8 A;  1UBY A;  3VJE A;  1FPS A;  2E93 A;  3PDE A;  2J5C A;  3RBM A;  4E9U A;  4JZB A;  4P0V A;  2ZCO A;  2Q58 A;  4F6X A;  3V1X A;  3WCE A;  5E8L A;  4LFV F;  1VG6 A;  1N1Z A;  3WC9 A; 
#chains in the Genus database with same CATH topology
 2AET A;  3SDU A;  5ERO A;  3SDR A;  3LJI A;  4ZQ8 A;  3WE9 A;  3ACY A;  5B00 A;  2Z50 A;  2ZCS A;  3M0G A;  4KQ5 A;  4JZX A;  4NFI F;  5DJP F;  3EZ3 A;  2Q80 A;  4NUA A;  2E8W A;  2PS5 A;  1N24 A;  3N6K F;  4KKM A;  4MC0 A;  4XQR F;  4KPD A;  3ICN A;  1HM7 A;  4KVW A;  4KQS A;  1JFG A;  3SDV A;  2ZEV A;  4MC3 A;  4UMJ A;  1HM4 A;  3LG5 A;  5EAT A;  2PS6 A;  3QQV A;  4N1Z F;  3WCM A;  4EA0 A;  1DGP A;  4N9U A;  5E8K A;  1YHK A;  3AQ0 A;  5IL3 A;  4LIX A;  4PVY F;  3PYA A;  5B0K A;  1YV5 A;  2OPN A;  4OGU A;  5ERN A;  2VF6 A;  4JXN A;  2AEL A;  4P0W A;  5B03 A;  5I1U A;  1WL1 A;  5CG6 A;  5ILJ A;  4LLT A;  4OMG A;  4XQS F;  4LFE A;  3WEG A;  4NFK F;  4LZ3 A;  5JV2 F;  3SDQ A;  4KK2 A;  5C05 A;  3WSB A;  5DHK A;  4OKZ A;  2AZJ A;  2E8T A;  2ZY1 A;  5HN7 A;  3KRO A;  4MC8 A;  2F89 F;  5A0J A;  3WEI A;  3KRC B;  5DW7 A;  3IPI A;  3M00 A;  4NKF A;  5IL8 A;  3WCC A;  5HN8 A;  4RXC A;  2F8C F;  3NF2 A;  5B01 A;  4LA5 A;  3N46 F;  3MZV A;  3WCJ A;  5H9D A;  3OAB B;  4P0X A;  3EFQ A;  4KQU A;  1V4H A;  3N0F A;  3ZL6 A;  2P1C A;  4QXS F;  2E8V A;  3OAC B;  5IMP A;  3KRF B;  1RQI A;  5IKA A;  5DIQ F;  3ICK A;  3N3L F;  3AQB B;  3WCH A;  2ONH A;  1JFA A;  3N5H F;  5DGS F;  2ZCR A;  5ILZ A;  3DYG A;  1V4K A;  2PS4 A;  4RNQ A;  2E91 A;  3CC9 A;  4DEM F;  3P5P A;  4E9Z A;  5DGN F;  2OA6 A;  4DI5 A;  3LDW A;  5A0K A;  3WJN A;  1HXA A;  3M01 A;  1YJ4 A;  2AZL A;  4RXD A;  4LUU A;  3WJO A;  4F6V A;  1N23 A;  3P5R A;  3NPK A;  5AEL A;  3VJ9 A;  1V4E A;  2H8O A;  4NFJ F;  4DWG A;  2Q9Z A;  5B0J A;  2E95 A;  1KIZ A;  4KFA A;  5B0M A;  2Z4V A;  3LLW A;  2PS8 A;  3KRA A;  5DZ2 A;  4FP4 A;  4KUX A;  3OYR A;  2DH4 A;  1YYU A;  2Q9Y A;  1WL2 A;  4LLS A;  2Z4W A;  5ILY A;  4K10 A;  3NPR A;  3N45 F;  4LTZ A;  2AZK A;  4LZ0 A;  4XQT F;  1YYQ A;  4RYP A;  5E8H A;  3S4J A;  1PS1 A;  1EZF A;  3N5J F;  5IMN A;  1WKZ A;  1WMW A;  4DWB A;  3P8L A;  1YYS A;  4GP1 A;  2Z4X A;  1VG7 A;  2Z4Z A;  3ZCD A;  3SAE A;  3ACW A;  2Z78 A;  2ZEU A;  5ILD A;  5ERM A;  3TS7 A;  5B0I A;  3APZ A;  3WCD A;  5B02 A;  5AFX A;  3SDT A;  3CKE A;  3S9V A;  2E90 A;  3VJD A;  2FOR A;  4EA1 A;  1V4J A;  3KBK A;  2EWG A;  2OGD A;  5DJR F;  3N1W F;  1RQJ A;  5DHI A;  4GA3 A;  3KRP A;  4Q23 A;  3ASX A;  3G4D A;  3Q2Z A;  3WCI A;  3Q30 A;  3WSA A;  1HX9 A;  2ZCQ A;  5JUZ F;  3N3D A;  3WCF A;  4OMH A;  1YHL A;  5IK0 A;  3WJK A;  1ZW5 A;  3LGZ B;  5IMI A;  4LZC A;  1WL0 A;  1HXC A;  4H5E F;  1UBX A;  3ZMC A;  1UBV A;  2I19 A;  5JV0 F;  4WK5 A;  4KVD A;  1UBW A;  1VG4 A;  3KRO B;  2F92 F;  3LEE A;  4QPF A;  4H5D F;  2ONG A;  1N22 A;  3VJC A;  3DYF A;  5ILK A;  3UCA A;  3LGK A;  5JA0 F;  3WCA A;  4LA6 A;  4KPJ A;  3KB9 A;  2O1O A;  3TFV A;  3TFN A;  3M02 A;  5ILH A;  3WCG A;  1YQ7 A;  3ICZ A;  5IKH A;  1HXG A;  3EGT A;  2J1O A;  3DYH A;  3BNX A;  3WCB A;  1V4I A;  4FJQ A;  3ACX A;  4DXJ A;  3ZMB A;  4OKM A;  3B7L A;  4KWD A;  3LZ9 A;  3V1V A;  3N0G A;  3BNY A;  5ER8 A;  1N21 A;  4GAX A;  3Q2Q A;  3WEH A;  4NG6 A;  2E8X A;  1VG3 A;  5B0L A;  3ZOU A;  5DJV F;  3QKC A;  3LMD A;  3N49 F;  4GP2 A;  1YYT A;  2AEK A;  1N20 A;  4NKE A;  4RXA A;  4LPH F;  5AYP A;  4JVJ F;  2Z52 A;  3KRC A;  5JV1 F;  4JYX A;  4LOB A;  5IK6 A;  5IVG A;  4DZW A;  5CG5 A;  5HN9 A;  1YHM A;  2OPM A;  5HNA A;  4LFG A;  5IN8 A;  3PYB A;  3G4F A;  2E8U A;  3CP6 A;  3KRA B;  1VG2 A;  3OAB A;  3AE0 A;  3AQC B;  2Z7I A;  4JXY A;  1WL3 A;  2Z7H A;  2Z4Y A;  3WCL A;  3RMG A;  5EAS A;  3RYW A;  4E1E A;  4KVY A;  3OAC A;  2FTZ A;  5IK9 A;  2F9K F;  3KRF A;  2RAH A;  4DHD A;  1KIY A;  5IM1 A;  3M9U A;  4LPG F;  3VJA A;  2E4O A;  3Q1O A;  3LK5 A;  4LTV A;  2PS7 A;  3LVS A;  3RYE A;  3WEF A;  5AHU B;  3TFP A;  2F94 F;  3ADZ A;  4RXE A;  1RTR A;  3WEK A;  3LOM A;  5EAU A;  3PKO A;  3P41 A;  3W7F A;  2F8Z F;  5A0I A;  4F62 A;  3WEJ A;  2E94 A;  5DGM F;  3TC1 A;  1DI1 A;  2J1P A;  1N1B A;  1WY0 A;  3IBA A;  4KVI A;  4PVX F;  3P8R A;  3ID0 A;  3PH7 A;  4HD1 A;  3VJB A;  4H5C F;  3NRI A;  5ILI A;  5KSX F;  1YYR A;  4EA2 A;  3LSN A;  3ICM A;  4L2X F;  2E92 A;  3KRP B;  2QIS A;  3N1V F;  3V66 A;  4LXW A;  2F7M F;  3MAV A;  3VJ8 A;  1UBY A;  3VJE A;  1FPS A;  2E93 A;  3PDE A;  2J5C A;  3RBM A;  4E9U A;  4JZB A;  4P0V A;  2ZCO A;  2Q58 A;  4F6X A;  3V1X A;  3WCE A;  5E8L A;  4LFV F;  1VG6 A;  1N1Z A;  3WC9 A; 
#chains in the Genus database with same CATH homology
 2AET A;  3SDU A;  5ERO A;  3SDR A;  3LJI A;  4ZQ8 A;  3WE9 A;  3ACY A;  5B00 A;  2Z50 A;  2ZCS A;  3M0G A;  4KQ5 A;  4JZX A;  4NFI F;  5DJP F;  3EZ3 A;  2Q80 A;  4NUA A;  2E8W A;  2PS5 A;  1N24 A;  3N6K F;  4KKM A;  4MC0 A;  4XQR F;  4KPD A;  3ICN A;  1HM7 A;  4KVW A;  4KQS A;  1JFG A;  3SDV A;  2ZEV A;  4MC3 A;  4UMJ A;  1HM4 A;  3LG5 A;  5EAT A;  2PS6 A;  3QQV A;  4N1Z F;  3WCM A;  4EA0 A;  1DGP A;  4N9U A;  5E8K A;  1YHK A;  3AQ0 A;  5IL3 A;  4LIX A;  4PVY F;  3PYA A;  5B0K A;  1YV5 A;  2OPN A;  4OGU A;  5ERN A;  2VF6 A;  4JXN A;  2AEL A;  4P0W A;  5B03 A;  5I1U A;  1WL1 A;  5CG6 A;  5ILJ A;  4LLT A;  4OMG A;  4XQS F;  4LFE A;  3WEG A;  4NFK F;  4LZ3 A;  5JV2 F;  3SDQ A;  4KK2 A;  5C05 A;  3WSB A;  5DHK A;  4OKZ A;  2AZJ A;  2E8T A;  2ZY1 A;  5HN7 A;  3KRO A;  4MC8 A;  2F89 F;  5A0J A;  3WEI A;  3KRC B;  5DW7 A;  3IPI A;  3M00 A;  4NKF A;  5IL8 A;  3WCC A;  5HN8 A;  4RXC A;  2F8C F;  3NF2 A;  5B01 A;  4LA5 A;  3N46 F;  3MZV A;  3WCJ A;  5H9D A;  3OAB B;  4P0X A;  3EFQ A;  4KQU A;  1V4H A;  3N0F A;  3ZL6 A;  2P1C A;  4QXS F;  2E8V A;  3OAC B;  5IMP A;  3KRF B;  1RQI A;  5IKA A;  5DIQ F;  3ICK A;  3N3L F;  3AQB B;  3WCH A;  2ONH A;  1JFA A;  3N5H F;  5DGS F;  2ZCR A;  5ILZ A;  3DYG A;  1V4K A;  2PS4 A;  4RNQ A;  2E91 A;  3CC9 A;  4DEM F;  3P5P A;  4E9Z A;  5DGN F;  2OA6 A;  4DI5 A;  3LDW A;  5A0K A;  3WJN A;  1HXA A;  3M01 A;  1YJ4 A;  2AZL A;  4RXD A;  4LUU A;  3WJO A;  4F6V A;  1N23 A;  3P5R A;  3NPK A;  5AEL A;  3VJ9 A;  1V4E A;  2H8O A;  4NFJ F;  4DWG A;  2Q9Z A;  5B0J A;  2E95 A;  1KIZ A;  4KFA A;  5B0M A;  2Z4V A;  3LLW A;  2PS8 A;  3KRA A;  5DZ2 A;  4FP4 A;  4KUX A;  3OYR A;  2DH4 A;  1YYU A;  2Q9Y A;  1WL2 A;  4LLS A;  2Z4W A;  5ILY A;  4K10 A;  3NPR A;  3N45 F;  4LTZ A;  2AZK A;  4LZ0 A;  4XQT F;  1YYQ A;  4RYP A;  5E8H A;  3S4J A;  1PS1 A;  1EZF A;  3N5J F;  5IMN A;  1WKZ A;  1WMW A;  4DWB A;  3P8L A;  1YYS A;  4GP1 A;  2Z4X A;  1VG7 A;  2Z4Z A;  3ZCD A;  3SAE A;  3ACW A;  2Z78 A;  2ZEU A;  5ILD A;  5ERM A;  3TS7 A;  5B0I A;  3APZ A;  3WCD A;  5B02 A;  5AFX A;  3SDT A;  3CKE A;  3S9V A;  2E90 A;  3VJD A;  2FOR A;  4EA1 A;  1V4J A;  3KBK A;  2EWG A;  2OGD A;  5DJR F;  3N1W F;  1RQJ A;  5DHI A;  4GA3 A;  3KRP A;  4Q23 A;  3ASX A;  3G4D A;  3Q2Z A;  3WCI A;  3Q30 A;  3WSA A;  1HX9 A;  2ZCQ A;  5JUZ F;  3N3D A;  3WCF A;  4OMH A;  1YHL A;  5IK0 A;  3WJK A;  1ZW5 A;  3LGZ B;  5IMI A;  4LZC A;  1WL0 A;  1HXC A;  4H5E F;  1UBX A;  3ZMC A;  1UBV A;  2I19 A;  5JV0 F;  4WK5 A;  4KVD A;  1UBW A;  1VG4 A;  3KRO B;  2F92 F;  3LEE A;  4QPF A;  4H5D F;  2ONG A;  1N22 A;  3VJC A;  3DYF A;  5ILK A;  3UCA A;  3LGK A;  5JA0 F;  3WCA A;  4LA6 A;  4KPJ A;  3KB9 A;  2O1O A;  3TFV A;  3TFN A;  3M02 A;  5ILH A;  3WCG A;  1YQ7 A;  3ICZ A;  5IKH A;  1HXG A;  3EGT A;  2J1O A;  3DYH A;  3BNX A;  3WCB A;  1V4I A;  4FJQ A;  3ACX A;  4DXJ A;  3ZMB A;  4OKM A;  3B7L A;  4KWD A;  3LZ9 A;  3V1V A;  3N0G A;  3BNY A;  5ER8 A;  1N21 A;  4GAX A;  3Q2Q A;  3WEH A;  4NG6 A;  2E8X A;  1VG3 A;  5B0L A;  3ZOU A;  5DJV F;  3QKC A;  3LMD A;  3N49 F;  4GP2 A;  1YYT A;  2AEK A;  1N20 A;  4NKE A;  4RXA A;  4LPH F;  5AYP A;  4JVJ F;  2Z52 A;  3KRC A;  5JV1 F;  4JYX A;  4LOB A;  5IK6 A;  5IVG A;  4DZW A;  5CG5 A;  5HN9 A;  1YHM A;  2OPM A;  5HNA A;  4LFG A;  5IN8 A;  3PYB A;  3G4F A;  2E8U A;  3CP6 A;  3KRA B;  1VG2 A;  3OAB A;  3AE0 A;  3AQC B;  2Z7I A;  4JXY A;  1WL3 A;  2Z7H A;  2Z4Y A;  3WCL A;  3RMG A;  5EAS A;  3RYW A;  4E1E A;  4KVY A;  3OAC A;  2FTZ A;  5IK9 A;  2F9K F;  3KRF A;  2RAH A;  4DHD A;  1KIY A;  5IM1 A;  3M9U A;  4LPG F;  3VJA A;  2E4O A;  3Q1O A;  3LK5 A;  4LTV A;  2PS7 A;  3LVS A;  3RYE A;  3WEF A;  5AHU B;  3TFP A;  2F94 F;  3ADZ A;  4RXE A;  1RTR A;  3WEK A;  3LOM A;  5EAU A;  3PKO A;  3P41 A;  3W7F A;  2F8Z F;  5A0I A;  4F62 A;  3WEJ A;  2E94 A;  5DGM F;  3TC1 A;  1DI1 A;  2J1P A;  1N1B A;  1WY0 A;  3IBA A;  4KVI A;  4PVX F;  3P8R A;  3ID0 A;  3PH7 A;  4HD1 A;  3VJB A;  4H5C F;  3NRI A;  5ILI A;  5KSX F;  1YYR A;  4EA2 A;  3LSN A;  3ICM A;  4L2X F;  2E92 A;  3KRP B;  2QIS A;  3N1V F;  3V66 A;  4LXW A;  2F7M F;  3MAV A;  3VJ8 A;  1UBY A;  3VJE A;  1FPS A;  2E93 A;  3PDE A;  2J5C A;  3RBM A;  4E9U A;  4JZB A;  4P0V A;  2ZCO A;  2Q58 A;  4F6X A;  3V1X A;  3WCE A;  5E8L A;  4LFV F;  1VG6 A;  1N1Z A;  3WC9 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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