4H5EF

Crystal structure of human fpps in ternary complex with ys0470 and isopentenyl pyrophosphate
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Farnesyl pyrophosphate synthase
publication title Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
pubmed doi rcsb
source organism Homo sapiens
total genus 136
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2012-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4h5eF00
4LTVA 4QXSF 4LLSA 3MAVA 2OGDA 3WJOA 2E95A 3G4FA 5AELA 2Z78A 4NG6A 4FJQA 5CG5A 5IKAA 1N1ZA 4OMHA 3ASXA 1N1BA 1V4IA 3WCDA 5A0JA 2F92F 3NPRA 2PS8A 4KFAA 4MC3A 4P0VA 3EGTA 3N45F 2F9KF 3VJ9A 4RYPA 3S4JA 4XQRF 1WL0A 1RQJA 3PH7A 1UBXA 4JVJF 4FP4A 4NFJF 4DHDA 4OGUA 2PS6A 5JV2F 3P5PA 3VJDA 3CP6A 4LTZA 4LA6A 5DIQF 3WCJA 2F8ZF 4XQSF 3LVSA 4KPJA 4PVYF 1YQ7A 2FORA 2PS7A 2F7MF 3TC1A 5ILZA 2Z4WA 1YHKA 2E90A 2Z4VA 5B0LA 4KVWA 5IM1A 1N21A 4XQTF 2F8CF 3WEIA 3M00A 1WMWA 5IL3A 4KK2A 5KSXF 2E92A 3WCHA 3N46F 2DH4A 3ID0A 3WCFA 3ICKA 3ZMCA 3VJEA 1WL3A 1PS1A 4KVDA 3ZCDA 3RYWA 3DYHA 3KROA 5DZ2A 4DEMF 3PYAA 5JV1F 3ICZA 3KRAB 5B01A 3VJCA 2Z50A 3ACYA 3DYFA 3KBKA 3N49F 2ONGA 4NUAA 4JZXA 3WSAA 3SDRA 3EFQA 2AETA 3NPKA 3LDWA 3Q2ZA 4LIXA 1WKZA 3LGZB 5DGSF 4DXJA 4E9ZA 5IMNA 5E8LA 3KRAA 5DHKA 4KPDA 3OYRA 3P8RA 5I1UA 2ZCRA 3EZ3A 5B00A 2Z52A 5B0JA 3WEGA 4OKZA 3WCGA 5JA0F 5HN7A 2AELA 1YYRA 5IK0A 3M9UA 3WCAA 4F6XA 1YHMA 3N0GA 5EASA 2E8TA 3VJ8A 3ICMA 4DWBA 2ZCQA 3M01A 5AHUB 4DZWA 5JUZF 3N5JF 1V4HA 5H9DA 3RMGA 2Q80A 3N6KF 1EZFA 1HM7A 4GAXA 4EA0A 1YYUA 1V4KA 4E9UA 3LOMA 4ZQ8A 1FPSA 3WE9A 3LMDA 3ZMBA 3W7FA 5EATA 3WSBA 5IMPA 2AEKA 4LOBA 4DWGA 3WC9A 2J1PA 4H5DF 4P0WA 5HNAA 1HX9A 3KRPA 2H8OA 3KRFA 4EA1A 2Z4XA 3APZA 5IK6A 2E8VA 4E1EA 4F6VA 3Q30A 2VF6A 2Z4ZA 3WJKA 3WCBA 2AZJA 3KROB 3WEFA 3OACA 3ZOUA 4KKMA 4JXNA 3QQVA 5ILKA 5B0MA 5DJRF 2P1CA 1N24A 3LLWA 3ZL6A 3NRIA 1JFAA 2E8XA 3WEKA 3SDTA 5DW7A 1RQIA 5AYPA 3VJAA 3WEHA 2E94A 5DJPF 4LPGF 5DJVF 2Q9ZA 3OABA 5ILIA 1RTRA 3P5RA 2AZKA 4F62A 3ACXA 5EAUA 4OMGA 3SDQA 3KRCB 2OPMA 4RXAA 3TFNA 2ZCSA 3B7LA 3WCLA 2E8UA 3M0GA 1KIZA 2FTZA 4KVYA 5JV0F 4OKMA 3AQBB 1JFGA 1YYQA 4LA5A 4UMJA 3CC9A 4HD1A 4LFGA 3WCIA 1HM4A 1DGPA 3ADZA 3WJNA 4KQ5A 4LPHF 2Q58A 4NFIF 3WCCA 1WY0A 4H5CF 3WEJA 1KIYA 1V4EA 3LSNA 5CG6A 3PDEA 3KRCA 2ZY1A 1UBWA 4MC8A 3DYGA 2J1OA 1V4JA 4LUUA 3P8LA 2F89F 4JYXA 3SDUA 5DHIA 3KB9A 2J5CA 3KRPB 2RAHA 5IMIA 3KRFB 5ILDA 5IVGA 2F94F 5EROA 3V1VA 3N5HF 1DI1A 4KQSA 4QPFA 3LEEA 4NKFA 5ILJA 2PS4A 4LZ0A 5AFXA 4LZCA 5DGNF 3AQCB 3Q1OA 3RYEA 4L2XF 4GP1A 3WCMA 5ILYA 3OACB 4NKEA 1VG6A 3QKCA 5DGMF 1N23A 4KVIA 2Z7HA 3M02A 5B02A 4RXDA 2E93A 3AQ0A 2OPNA 4KUXA 4N1ZF 5IKHA 4GA3A 4KWDA 5A0IA 1WL2A 1HXCA 4H5EF 3PYBA 4LXWA 1YYTA 3LK5A 3IBAA 4RXEA 3LJIA 3N0FA 2Q9YA 3OABB 3TFVA 2ONHA 3UCAA 1UBYA 1VG7A 3SDVA 1YYSA 4WK5A 5A0KA 2ZCOA 3N1VF 3N3LF 5B0IA 4JZBA 2I19A 3LG5A 3G4DA 4MC0A 2AZLA 2EWGA 2QISA 2E8WA 3N3DA 5IK9A 2ZEVA 4K10A 5E8HA 3MZVA 2PS5A 5HN8A 3ACWA 2E4OA 2ZEUA 3LZ9A 3CKEA 3VJBA 1WL1A 3V1XA 5B03A 3BNYA 3IPIA 2OA6A 1VG2A 5ERMA 4LZ3A 3S9VA 5C05A 3ICNA 4EA2A 1YV5A 5B0KA 5ER8A 3WCEA 5IN8A 1N20A 3NF2A 4LLTA 3P41A 4DI5A 1VG4A 3TS7A 1VG3A 1HXGA 1YHLA 1HXAA 4JXYA 1N22A 5E8KA 3TFPA 4KQUA 4RNQA 3V66A 3N1WF 4Q23A 4PVXF 3AE0A 1ZW5A 4RXCA 4NFKF 4N9UA 3RBMA 3LGKA 3BNXA 2Z4YA 4GP2A 2Z7IA 3SAEA 1UBVA 2E91A 2O1OA 5ERNA 5HN9A 4LFVF 1YJ4A 3PKOA 5ILHA 3Q2QA 4P0XA 5IL8A 4LFEA
chains in the Genus database with same CATH superfamily
4LTVA 4QXSF 4LLSA 3MAVA 2OGDA 3WJOA 2E95A 3G4FA 5AELA 2Z78A 4NG6A 4FJQA 5CG5A 5IKAA 1N1ZA 4OMHA 3ASXA 1N1BA 1V4IA 3WCDA 5A0JA 2F92F 3NPRA 2PS8A 4KFAA 4MC3A 4P0VA 3EGTA 3N45F 2F9KF 3VJ9A 4RYPA 3S4JA 4XQRF 1WL0A 1RQJA 3PH7A 1UBXA 4JVJF 4FP4A 4NFJF 4DHDA 4OGUA 2PS6A 5JV2F 3P5PA 3VJDA 3CP6A 4LTZA 4LA6A 5DIQF 3WCJA 2F8ZF 4XQSF 3LVSA 4KPJA 4PVYF 1YQ7A 2FORA 2PS7A 2F7MF 3TC1A 5ILZA 2Z4WA 1YHKA 2E90A 2Z4VA 5B0LA 4KVWA 5IM1A 1N21A 4XQTF 2F8CF 3WEIA 3M00A 1WMWA 5IL3A 4KK2A 5KSXF 2E92A 3WCHA 3N46F 2DH4A 3ID0A 3WCFA 3ICKA 3ZMCA 3VJEA 1WL3A 1PS1A 4KVDA 3ZCDA 3RYWA 3DYHA 3KROA 5DZ2A 4DEMF 3PYAA 5JV1F 3ICZA 3KRAB 5B01A 3VJCA 2Z50A 3ACYA 3DYFA 3KBKA 3N49F 2ONGA 4NUAA 4JZXA 3WSAA 3SDRA 3EFQA 2AETA 3NPKA 3LDWA 3Q2ZA 4LIXA 1WKZA 3LGZB 5DGSF 4DXJA 4E9ZA 5IMNA 5E8LA 3KRAA 5DHKA 4KPDA 3OYRA 3P8RA 5I1UA 2ZCRA 3EZ3A 5B00A 2Z52A 5B0JA 3WEGA 4OKZA 3WCGA 5JA0F 5HN7A 2AELA 1YYRA 5IK0A 3M9UA 3WCAA 4F6XA 1YHMA 3N0GA 5EASA 2E8TA 3VJ8A 3ICMA 4DWBA 2ZCQA 3M01A 5AHUB 4DZWA 5JUZF 3N5JF 1V4HA 5H9DA 3RMGA 2Q80A 3N6KF 1EZFA 1HM7A 4GAXA 4EA0A 1YYUA 1V4KA 4E9UA 3LOMA 4ZQ8A 1FPSA 3WE9A 3LMDA 3ZMBA 3W7FA 5EATA 3WSBA 5IMPA 2AEKA 4LOBA 4DWGA 3WC9A 2J1PA 4H5DF 4P0WA 5HNAA 1HX9A 3KRPA 2H8OA 3KRFA 4EA1A 2Z4XA 3APZA 5IK6A 2E8VA 4E1EA 4F6VA 3Q30A 2VF6A 2Z4ZA 3WJKA 3WCBA 2AZJA 3KROB 3WEFA 3OACA 3ZOUA 4KKMA 4JXNA 3QQVA 5ILKA 5B0MA 5DJRF 2P1CA 1N24A 3LLWA 3ZL6A 3NRIA 1JFAA 2E8XA 3WEKA 3SDTA 5DW7A 1RQIA 5AYPA 3VJAA 3WEHA 2E94A 5DJPF 4LPGF 5DJVF 2Q9ZA 3OABA 5ILIA 1RTRA 3P5RA 2AZKA 4F62A 3ACXA 5EAUA 4OMGA 3SDQA 3KRCB 2OPMA 4RXAA 3TFNA 2ZCSA 3B7LA 3WCLA 2E8UA 3M0GA 1KIZA 2FTZA 4KVYA 5JV0F 4OKMA 3AQBB 1JFGA 1YYQA 4LA5A 4UMJA 3CC9A 4HD1A 4LFGA 3WCIA 1HM4A 1DGPA 3ADZA 3WJNA 4KQ5A 4LPHF 2Q58A 4NFIF 3WCCA 1WY0A 4H5CF 3WEJA 1KIYA 1V4EA 3LSNA 5CG6A 3PDEA 3KRCA 2ZY1A 1UBWA 4MC8A 3DYGA 2J1OA 1V4JA 4LUUA 3P8LA 2F89F 4JYXA 3SDUA 5DHIA 3KB9A 2J5CA 3KRPB 2RAHA 5IMIA 3KRFB 5ILDA 5IVGA 2F94F 5EROA 3V1VA 3N5HF 1DI1A 4KQSA 4QPFA 3LEEA 4NKFA 5ILJA 2PS4A 4LZ0A 5AFXA 4LZCA 5DGNF 3AQCB 3Q1OA 3RYEA 4L2XF 4GP1A 3WCMA 5ILYA 3OACB 4NKEA 1VG6A 3QKCA 5DGMF 1N23A 4KVIA 2Z7HA 3M02A 5B02A 4RXDA 2E93A 3AQ0A 2OPNA 4KUXA 4N1ZF 5IKHA 4GA3A 4KWDA 5A0IA 1WL2A 1HXCA 4H5EF 3PYBA 4LXWA 1YYTA 3LK5A 3IBAA 4RXEA 3LJIA 3N0FA 2Q9YA 3OABB 3TFVA 2ONHA 3UCAA 1UBYA 1VG7A 3SDVA 1YYSA 4WK5A 5A0KA 2ZCOA 3N1VF 3N3LF 5B0IA 4JZBA 2I19A 3LG5A 3G4DA 4MC0A 2AZLA 2EWGA 2QISA 2E8WA 3N3DA 5IK9A 2ZEVA 4K10A 5E8HA 3MZVA 2PS5A 5HN8A 3ACWA 2E4OA 2ZEUA 3LZ9A 3CKEA 3VJBA 1WL1A 3V1XA 5B03A 3BNYA 3IPIA 2OA6A 1VG2A 5ERMA 4LZ3A 3S9VA 5C05A 3ICNA 4EA2A 1YV5A 5B0KA 5ER8A 3WCEA 5IN8A 1N20A 3NF2A 4LLTA 3P41A 4DI5A 1VG4A 3TS7A 1VG3A 1HXGA 1YHLA 1HXAA 4JXYA 1N22A 5E8KA 3TFPA 4KQUA 4RNQA 3V66A 3N1WF 4Q23A 4PVXF 3AE0A 1ZW5A 4RXCA 4NFKF 4N9UA 3RBMA 3LGKA 3BNXA 2Z4YA 4GP2A 2Z7IA 3SAEA 1UBVA 2E91A 2O1OA 5ERNA 5HN9A 4LFVF 1YJ4A 3PKOA 5ILHA 3Q2QA 4P0XA 5IL8A 4LFEA
chains in the Genus database with same CATH topology
4LTVA 4QXSF 4LLSA 3MAVA 2OGDA 3WJOA 2E95A 3G4FA 5AELA 2Z78A 4NG6A 4FJQA 5CG5A 5IKAA 1N1ZA 4OMHA 3ASXA 1N1BA 1V4IA 3WCDA 5A0JA 2F92F 3NPRA 2PS8A 4KFAA 4MC3A 4P0VA 3EGTA 3N45F 2F9KF 3VJ9A 4RYPA 3S4JA 4XQRF 1WL0A 1RQJA 3PH7A 1UBXA 4JVJF 4FP4A 4NFJF 4DHDA 4OGUA 2PS6A 5JV2F 3P5PA 3VJDA 3CP6A 4LTZA 4LA6A 5DIQF 3WCJA 2F8ZF 4XQSF 3LVSA 4KPJA 4PVYF 1YQ7A 2FORA 2PS7A 2F7MF 3TC1A 5ILZA 2Z4WA 1YHKA 2E90A 2Z4VA 5B0LA 4KVWA 5IM1A 1N21A 4XQTF 2F8CF 3WEIA 3M00A 1WMWA 5IL3A 4KK2A 5KSXF 2E92A 3WCHA 3N46F 2DH4A 3ID0A 3WCFA 3ICKA 3ZMCA 3VJEA 1WL3A 1PS1A 4KVDA 3ZCDA 3RYWA 3DYHA 3KROA 5DZ2A 4DEMF 3PYAA 5JV1F 3ICZA 3KRAB 5B01A 3VJCA 2Z50A 3ACYA 3DYFA 3KBKA 3N49F 2ONGA 4NUAA 4JZXA 3WSAA 3SDRA 3EFQA 2AETA 3NPKA 3LDWA 3Q2ZA 4LIXA 1WKZA 3LGZB 5DGSF 4DXJA 4E9ZA 5IMNA 5E8LA 3KRAA 5DHKA 4KPDA 3OYRA 3P8RA 5I1UA 2ZCRA 3EZ3A 5B00A 2Z52A 5B0JA 3WEGA 4OKZA 3WCGA 5JA0F 5HN7A 2AELA 1YYRA 5IK0A 3M9UA 3WCAA 4F6XA 1YHMA 3N0GA 5EASA 2E8TA 3VJ8A 3ICMA 4DWBA 2ZCQA 3M01A 5AHUB 4DZWA 5JUZF 3N5JF 1V4HA 5H9DA 3RMGA 2Q80A 3N6KF 1EZFA 1HM7A 4GAXA 4EA0A 1YYUA 1V4KA 4E9UA 3LOMA 4ZQ8A 1FPSA 3WE9A 3LMDA 3ZMBA 3W7FA 5EATA 3WSBA 5IMPA 2AEKA 4LOBA 4DWGA 3WC9A 2J1PA 4H5DF 4P0WA 5HNAA 1HX9A 3KRPA 2H8OA 3KRFA 4EA1A 2Z4XA 3APZA 5IK6A 2E8VA 4E1EA 4F6VA 3Q30A 2VF6A 2Z4ZA 3WJKA 3WCBA 2AZJA 3KROB 3WEFA 3OACA 3ZOUA 4KKMA 4JXNA 3QQVA 5ILKA 5B0MA 5DJRF 2P1CA 1N24A 3LLWA 3ZL6A 3NRIA 1JFAA 2E8XA 3WEKA 3SDTA 5DW7A 1RQIA 5AYPA 3VJAA 3WEHA 2E94A 5DJPF 4LPGF 5DJVF 2Q9ZA 3OABA 5ILIA 1RTRA 3P5RA 2AZKA 4F62A 3ACXA 5EAUA 4OMGA 3SDQA 3KRCB 2OPMA 4RXAA 3TFNA 2ZCSA 3B7LA 3WCLA 2E8UA 3M0GA 1KIZA 2FTZA 4KVYA 5JV0F 4OKMA 3AQBB 1JFGA 1YYQA 4LA5A 4UMJA 3CC9A 4HD1A 4LFGA 3WCIA 1HM4A 1DGPA 3ADZA 3WJNA 4KQ5A 4LPHF 2Q58A 4NFIF 3WCCA 1WY0A 4H5CF 3WEJA 1KIYA 1V4EA 3LSNA 5CG6A 3PDEA 3KRCA 2ZY1A 1UBWA 4MC8A 3DYGA 2J1OA 1V4JA 4LUUA 3P8LA 2F89F 4JYXA 3SDUA 5DHIA 3KB9A 2J5CA 3KRPB 2RAHA 5IMIA 3KRFB 5ILDA 5IVGA 2F94F 5EROA 3V1VA 3N5HF 1DI1A 4KQSA 4QPFA 3LEEA 4NKFA 5ILJA 2PS4A 4LZ0A 5AFXA 4LZCA 5DGNF 3AQCB 3Q1OA 3RYEA 4L2XF 4GP1A 3WCMA 5ILYA 3OACB 4NKEA 1VG6A 3QKCA 5DGMF 1N23A 4KVIA 2Z7HA 3M02A 5B02A 4RXDA 2E93A 3AQ0A 2OPNA 4KUXA 4N1ZF 5IKHA 4GA3A 4KWDA 5A0IA 1WL2A 1HXCA 4H5EF 3PYBA 4LXWA 1YYTA 3LK5A 3IBAA 4RXEA 3LJIA 3N0FA 2Q9YA 3OABB 3TFVA 2ONHA 3UCAA 1UBYA 1VG7A 3SDVA 1YYSA 4WK5A 5A0KA 2ZCOA 3N1VF 3N3LF 5B0IA 4JZBA 2I19A 3LG5A 3G4DA 4MC0A 2AZLA 2EWGA 2QISA 2E8WA 3N3DA 5IK9A 2ZEVA 4K10A 5E8HA 3MZVA 2PS5A 5HN8A 3ACWA 2E4OA 2ZEUA 3LZ9A 3CKEA 3VJBA 1WL1A 3V1XA 5B03A 3BNYA 3IPIA 2OA6A 1VG2A 5ERMA 4LZ3A 3S9VA 5C05A 3ICNA 4EA2A 1YV5A 5B0KA 5ER8A 3WCEA 5IN8A 1N20A 3NF2A 4LLTA 3P41A 4DI5A 1VG4A 3TS7A 1VG3A 1HXGA 1YHLA 1HXAA 4JXYA 1N22A 5E8KA 3TFPA 4KQUA 4RNQA 3V66A 3N1WF 4Q23A 4PVXF 3AE0A 1ZW5A 4RXCA 4NFKF 4N9UA 3RBMA 3LGKA 3BNXA 2Z4YA 4GP2A 2Z7IA 3SAEA 1UBVA 2E91A 2O1OA 5ERNA 5HN9A 4LFVF 1YJ4A 3PKOA 5ILHA 3Q2QA 4P0XA 5IL8A 4LFEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LTV A;  4QXS F;  4LLS A;  3MAV A;  2OGD A;  3WJO A;  2E95 A;  3G4F A;  5AEL A;  2Z78 A;  4NG6 A;  4FJQ A;  5CG5 A;  5IKA A;  1N1Z A;  4OMH A;  3ASX A;  1N1B A;  1V4I A;  3WCD A;  5A0J A;  2F92 F;  3NPR A;  2PS8 A;  4KFA A;  4MC3 A;  4P0V A;  3EGT A;  3N45 F;  2F9K F;  3VJ9 A;  4RYP A;  3S4J A;  4XQR F;  1WL0 A;  1RQJ A;  3PH7 A;  1UBX A;  4JVJ F;  4FP4 A;  4NFJ F;  4DHD A;  4OGU A;  2PS6 A;  5JV2 F;  3P5P A;  3VJD A;  3CP6 A;  4LTZ A;  4LA6 A;  5DIQ F;  3WCJ A;  2F8Z F;  4XQS F;  3LVS A;  4KPJ A;  4PVY F;  1YQ7 A;  2FOR A;  2PS7 A;  2F7M F;  3TC1 A;  5ILZ A;  2Z4W A;  1YHK A;  2E90 A;  2Z4V A;  5B0L A;  4KVW A;  5IM1 A;  1N21 A;  4XQT F;  2F8C F;  3WEI A;  3M00 A;  1WMW A;  5IL3 A;  4KK2 A;  5KSX F;  2E92 A;  3WCH A;  3N46 F;  2DH4 A;  3ID0 A;  3WCF A;  3ICK A;  3ZMC A;  3VJE A;  1WL3 A;  1PS1 A;  4KVD A;  3ZCD A;  3RYW A;  3DYH A;  3KRO A;  5DZ2 A;  4DEM F;  3PYA A;  5JV1 F;  3ICZ A;  3KRA B;  5B01 A;  3VJC A;  2Z50 A;  3ACY A;  3DYF A;  3KBK A;  3N49 F;  2ONG A;  4NUA A;  4JZX A;  3WSA A;  3SDR A;  3EFQ A;  2AET A;  3NPK A;  3LDW A;  3Q2Z A;  4LIX A;  1WKZ A;  3LGZ B;  5DGS F;  4DXJ A;  4E9Z A;  5IMN A;  5E8L A;  3KRA A;  5DHK A;  4KPD A;  3OYR A;  3P8R A;  5I1U A;  2ZCR A;  3EZ3 A;  5B00 A;  2Z52 A;  5B0J A;  3WEG A;  4OKZ A;  3WCG A;  5JA0 F;  5HN7 A;  2AEL A;  1YYR A;  5IK0 A;  3M9U A;  3WCA A;  4F6X A;  1YHM A;  3N0G A;  5EAS A;  2E8T A;  3VJ8 A;  3ICM A;  4DWB A;  2ZCQ A;  3M01 A;  5AHU B;  4DZW A;  5JUZ F;  3N5J F;  1V4H A;  5H9D A;  3RMG A;  2Q80 A;  3N6K F;  1EZF A;  1HM7 A;  4GAX A;  4EA0 A;  1YYU A;  1V4K A;  4E9U A;  3LOM A;  4ZQ8 A;  1FPS A;  3WE9 A;  3LMD A;  3ZMB A;  3W7F A;  5EAT A;  3WSB A;  5IMP A;  2AEK A;  4LOB A;  4DWG A;  3WC9 A;  2J1P A;  4H5D F;  4P0W A;  5HNA A;  1HX9 A;  3KRP A;  2H8O A;  3KRF A;  4EA1 A;  2Z4X A;  3APZ A;  5IK6 A;  2E8V A;  4E1E A;  4F6V A;  3Q30 A;  2VF6 A;  2Z4Z A;  3WJK A;  3WCB A;  2AZJ A;  3KRO B;  3WEF A;  3OAC A;  3ZOU A;  4KKM A;  4JXN A;  3QQV A;  5ILK A;  5B0M A;  5DJR F;  2P1C A;  1N24 A;  3LLW A;  3ZL6 A;  3NRI A;  1JFA A;  2E8X A;  3WEK A;  3SDT A;  5DW7 A;  1RQI A;  5AYP A;  3VJA A;  3WEH A;  2E94 A;  5DJP F;  4LPG F;  5DJV F;  2Q9Z A;  3OAB A;  5ILI A;  1RTR A;  3P5R A;  2AZK A;  4F62 A;  3ACX A;  5EAU A;  4OMG A;  3SDQ A;  3KRC B;  2OPM A;  4RXA A;  3TFN A;  2ZCS A;  3B7L A;  3WCL A;  2E8U A;  3M0G A;  1KIZ A;  2FTZ A;  4KVY A;  5JV0 F;  4OKM A;  3AQB B;  1JFG A;  1YYQ A;  4LA5 A;  4UMJ A;  3CC9 A;  4HD1 A;  4LFG A;  3WCI A;  1HM4 A;  1DGP A;  3ADZ A;  3WJN A;  4KQ5 A;  4LPH F;  2Q58 A;  4NFI F;  3WCC A;  1WY0 A;  4H5C F;  3WEJ A;  1KIY A;  1V4E A;  3LSN A;  5CG6 A;  3PDE A;  3KRC A;  2ZY1 A;  1UBW A;  4MC8 A;  3DYG A;  2J1O A;  1V4J A;  4LUU A;  3P8L A;  2F89 F;  4JYX A;  3SDU A;  5DHI A;  3KB9 A;  2J5C A;  3KRP B;  2RAH A;  5IMI A;  3KRF B;  5ILD A;  5IVG A;  2F94 F;  5ERO A;  3V1V A;  3N5H F;  1DI1 A;  4KQS A;  4QPF A;  3LEE A;  4NKF A;  5ILJ A;  2PS4 A;  4LZ0 A;  5AFX A;  4LZC A;  5DGN F;  3AQC B;  3Q1O A;  3RYE A;  4L2X F;  4GP1 A;  3WCM A;  5ILY A;  3OAC B;  4NKE A;  1VG6 A;  3QKC A;  5DGM F;  1N23 A;  4KVI A;  2Z7H A;  3M02 A;  5B02 A;  4RXD A;  2E93 A;  3AQ0 A;  2OPN A;  4KUX A;  4N1Z F;  5IKH A;  4GA3 A;  4KWD A;  5A0I A;  1WL2 A;  1HXC A;  4H5E F;  3PYB A;  4LXW A;  1YYT A;  3LK5 A;  3IBA A;  4RXE A;  3LJI A;  3N0F A;  2Q9Y A;  3OAB B;  3TFV A;  2ONH A;  3UCA A;  1UBY A;  1VG7 A;  3SDV A;  1YYS A;  4WK5 A;  5A0K A;  2ZCO A;  3N1V F;  3N3L F;  5B0I A;  4JZB A;  2I19 A;  3LG5 A;  3G4D A;  4MC0 A;  2AZL A;  2EWG A;  2QIS A;  2E8W A;  3N3D A;  5IK9 A;  2ZEV A;  4K10 A;  5E8H A;  3MZV A;  2PS5 A;  5HN8 A;  3ACW A;  2E4O A;  2ZEU A;  3LZ9 A;  3CKE A;  3VJB A;  1WL1 A;  3V1X A;  5B03 A;  3BNY A;  3IPI A;  2OA6 A;  1VG2 A;  5ERM A;  4LZ3 A;  3S9V A;  5C05 A;  3ICN A;  4EA2 A;  1YV5 A;  5B0K A;  5ER8 A;  3WCE A;  5IN8 A;  1N20 A;  3NF2 A;  4LLT A;  3P41 A;  4DI5 A;  1VG4 A;  3TS7 A;  1VG3 A;  1HXG A;  1YHL A;  1HXA A;  4JXY A;  1N22 A;  5E8K A;  3TFP A;  4KQU A;  4RNQ A;  3V66 A;  3N1W F;  4Q23 A;  4PVX F;  3AE0 A;  1ZW5 A;  4RXC A;  4NFK F;  4N9U A;  3RBM A;  3LGK A;  3BNX A;  2Z4Y A;  4GP2 A;  2Z7I A;  3SAE A;  1UBV A;  2E91 A;  2O1O A;  5ERN A;  5HN9 A;  4LFV F;  1YJ4 A;  3PKO A;  5ILH A;  3Q2Q A;  4P0X A;  5IL8 A;  4LFE A; 
#chains in the Genus database with same CATH topology
 4LTV A;  4QXS F;  4LLS A;  3MAV A;  2OGD A;  3WJO A;  2E95 A;  3G4F A;  5AEL A;  2Z78 A;  4NG6 A;  4FJQ A;  5CG5 A;  5IKA A;  1N1Z A;  4OMH A;  3ASX A;  1N1B A;  1V4I A;  3WCD A;  5A0J A;  2F92 F;  3NPR A;  2PS8 A;  4KFA A;  4MC3 A;  4P0V A;  3EGT A;  3N45 F;  2F9K F;  3VJ9 A;  4RYP A;  3S4J A;  4XQR F;  1WL0 A;  1RQJ A;  3PH7 A;  1UBX A;  4JVJ F;  4FP4 A;  4NFJ F;  4DHD A;  4OGU A;  2PS6 A;  5JV2 F;  3P5P A;  3VJD A;  3CP6 A;  4LTZ A;  4LA6 A;  5DIQ F;  3WCJ A;  2F8Z F;  4XQS F;  3LVS A;  4KPJ A;  4PVY F;  1YQ7 A;  2FOR A;  2PS7 A;  2F7M F;  3TC1 A;  5ILZ A;  2Z4W A;  1YHK A;  2E90 A;  2Z4V A;  5B0L A;  4KVW A;  5IM1 A;  1N21 A;  4XQT F;  2F8C F;  3WEI A;  3M00 A;  1WMW A;  5IL3 A;  4KK2 A;  5KSX F;  2E92 A;  3WCH A;  3N46 F;  2DH4 A;  3ID0 A;  3WCF A;  3ICK A;  3ZMC A;  3VJE A;  1WL3 A;  1PS1 A;  4KVD A;  3ZCD A;  3RYW A;  3DYH A;  3KRO A;  5DZ2 A;  4DEM F;  3PYA A;  5JV1 F;  3ICZ A;  3KRA B;  5B01 A;  3VJC A;  2Z50 A;  3ACY A;  3DYF A;  3KBK A;  3N49 F;  2ONG A;  4NUA A;  4JZX A;  3WSA A;  3SDR A;  3EFQ A;  2AET A;  3NPK A;  3LDW A;  3Q2Z A;  4LIX A;  1WKZ A;  3LGZ B;  5DGS F;  4DXJ A;  4E9Z A;  5IMN A;  5E8L A;  3KRA A;  5DHK A;  4KPD A;  3OYR A;  3P8R A;  5I1U A;  2ZCR A;  3EZ3 A;  5B00 A;  2Z52 A;  5B0J A;  3WEG A;  4OKZ A;  3WCG A;  5JA0 F;  5HN7 A;  2AEL A;  1YYR A;  5IK0 A;  3M9U A;  3WCA A;  4F6X A;  1YHM A;  3N0G A;  5EAS A;  2E8T A;  3VJ8 A;  3ICM A;  4DWB A;  2ZCQ A;  3M01 A;  5AHU B;  4DZW A;  5JUZ F;  3N5J F;  1V4H A;  5H9D A;  3RMG A;  2Q80 A;  3N6K F;  1EZF A;  1HM7 A;  4GAX A;  4EA0 A;  1YYU A;  1V4K A;  4E9U A;  3LOM A;  4ZQ8 A;  1FPS A;  3WE9 A;  3LMD A;  3ZMB A;  3W7F A;  5EAT A;  3WSB A;  5IMP A;  2AEK A;  4LOB A;  4DWG A;  3WC9 A;  2J1P A;  4H5D F;  4P0W A;  5HNA A;  1HX9 A;  3KRP A;  2H8O A;  3KRF A;  4EA1 A;  2Z4X A;  3APZ A;  5IK6 A;  2E8V A;  4E1E A;  4F6V A;  3Q30 A;  2VF6 A;  2Z4Z A;  3WJK A;  3WCB A;  2AZJ A;  3KRO B;  3WEF A;  3OAC A;  3ZOU A;  4KKM A;  4JXN A;  3QQV A;  5ILK A;  5B0M A;  5DJR F;  2P1C A;  1N24 A;  3LLW A;  3ZL6 A;  3NRI A;  1JFA A;  2E8X A;  3WEK A;  3SDT A;  5DW7 A;  1RQI A;  5AYP A;  3VJA A;  3WEH A;  2E94 A;  5DJP F;  4LPG F;  5DJV F;  2Q9Z A;  3OAB A;  5ILI A;  1RTR A;  3P5R A;  2AZK A;  4F62 A;  3ACX A;  5EAU A;  4OMG A;  3SDQ A;  3KRC B;  2OPM A;  4RXA A;  3TFN A;  2ZCS A;  3B7L A;  3WCL A;  2E8U A;  3M0G A;  1KIZ A;  2FTZ A;  4KVY A;  5JV0 F;  4OKM A;  3AQB B;  1JFG A;  1YYQ A;  4LA5 A;  4UMJ A;  3CC9 A;  4HD1 A;  4LFG A;  3WCI A;  1HM4 A;  1DGP A;  3ADZ A;  3WJN A;  4KQ5 A;  4LPH F;  2Q58 A;  4NFI F;  3WCC A;  1WY0 A;  4H5C F;  3WEJ A;  1KIY A;  1V4E A;  3LSN A;  5CG6 A;  3PDE A;  3KRC A;  2ZY1 A;  1UBW A;  4MC8 A;  3DYG A;  2J1O A;  1V4J A;  4LUU A;  3P8L A;  2F89 F;  4JYX A;  3SDU A;  5DHI A;  3KB9 A;  2J5C A;  3KRP B;  2RAH A;  5IMI A;  3KRF B;  5ILD A;  5IVG A;  2F94 F;  5ERO A;  3V1V A;  3N5H F;  1DI1 A;  4KQS A;  4QPF A;  3LEE A;  4NKF A;  5ILJ A;  2PS4 A;  4LZ0 A;  5AFX A;  4LZC A;  5DGN F;  3AQC B;  3Q1O A;  3RYE A;  4L2X F;  4GP1 A;  3WCM A;  5ILY A;  3OAC B;  4NKE A;  1VG6 A;  3QKC A;  5DGM F;  1N23 A;  4KVI A;  2Z7H A;  3M02 A;  5B02 A;  4RXD A;  2E93 A;  3AQ0 A;  2OPN A;  4KUX A;  4N1Z F;  5IKH A;  4GA3 A;  4KWD A;  5A0I A;  1WL2 A;  1HXC A;  4H5E F;  3PYB A;  4LXW A;  1YYT A;  3LK5 A;  3IBA A;  4RXE A;  3LJI A;  3N0F A;  2Q9Y A;  3OAB B;  3TFV A;  2ONH A;  3UCA A;  1UBY A;  1VG7 A;  3SDV A;  1YYS A;  4WK5 A;  5A0K A;  2ZCO A;  3N1V F;  3N3L F;  5B0I A;  4JZB A;  2I19 A;  3LG5 A;  3G4D A;  4MC0 A;  2AZL A;  2EWG A;  2QIS A;  2E8W A;  3N3D A;  5IK9 A;  2ZEV A;  4K10 A;  5E8H A;  3MZV A;  2PS5 A;  5HN8 A;  3ACW A;  2E4O A;  2ZEU A;  3LZ9 A;  3CKE A;  3VJB A;  1WL1 A;  3V1X A;  5B03 A;  3BNY A;  3IPI A;  2OA6 A;  1VG2 A;  5ERM A;  4LZ3 A;  3S9V A;  5C05 A;  3ICN A;  4EA2 A;  1YV5 A;  5B0K A;  5ER8 A;  3WCE A;  5IN8 A;  1N20 A;  3NF2 A;  4LLT A;  3P41 A;  4DI5 A;  1VG4 A;  3TS7 A;  1VG3 A;  1HXG A;  1YHL A;  1HXA A;  4JXY A;  1N22 A;  5E8K A;  3TFP A;  4KQU A;  4RNQ A;  3V66 A;  3N1W F;  4Q23 A;  4PVX F;  3AE0 A;  1ZW5 A;  4RXC A;  4NFK F;  4N9U A;  3RBM A;  3LGK A;  3BNX A;  2Z4Y A;  4GP2 A;  2Z7I A;  3SAE A;  1UBV A;  2E91 A;  2O1O A;  5ERN A;  5HN9 A;  4LFV F;  1YJ4 A;  3PKO A;  5ILH A;  3Q2Q A;  4P0X A;  5IL8 A;  4LFE A; 
#chains in the Genus database with same CATH homology
 4LTV A;  4QXS F;  4LLS A;  3MAV A;  2OGD A;  3WJO A;  2E95 A;  3G4F A;  5AEL A;  2Z78 A;  4NG6 A;  4FJQ A;  5CG5 A;  5IKA A;  1N1Z A;  4OMH A;  3ASX A;  1N1B A;  1V4I A;  3WCD A;  5A0J A;  2F92 F;  3NPR A;  2PS8 A;  4KFA A;  4MC3 A;  4P0V A;  3EGT A;  3N45 F;  2F9K F;  3VJ9 A;  4RYP A;  3S4J A;  4XQR F;  1WL0 A;  1RQJ A;  3PH7 A;  1UBX A;  4JVJ F;  4FP4 A;  4NFJ F;  4DHD A;  4OGU A;  2PS6 A;  5JV2 F;  3P5P A;  3VJD A;  3CP6 A;  4LTZ A;  4LA6 A;  5DIQ F;  3WCJ A;  2F8Z F;  4XQS F;  3LVS A;  4KPJ A;  4PVY F;  1YQ7 A;  2FOR A;  2PS7 A;  2F7M F;  3TC1 A;  5ILZ A;  2Z4W A;  1YHK A;  2E90 A;  2Z4V A;  5B0L A;  4KVW A;  5IM1 A;  1N21 A;  4XQT F;  2F8C F;  3WEI A;  3M00 A;  1WMW A;  5IL3 A;  4KK2 A;  5KSX F;  2E92 A;  3WCH A;  3N46 F;  2DH4 A;  3ID0 A;  3WCF A;  3ICK A;  3ZMC A;  3VJE A;  1WL3 A;  1PS1 A;  4KVD A;  3ZCD A;  3RYW A;  3DYH A;  3KRO A;  5DZ2 A;  4DEM F;  3PYA A;  5JV1 F;  3ICZ A;  3KRA B;  5B01 A;  3VJC A;  2Z50 A;  3ACY A;  3DYF A;  3KBK A;  3N49 F;  2ONG A;  4NUA A;  4JZX A;  3WSA A;  3SDR A;  3EFQ A;  2AET A;  3NPK A;  3LDW A;  3Q2Z A;  4LIX A;  1WKZ A;  3LGZ B;  5DGS F;  4DXJ A;  4E9Z A;  5IMN A;  5E8L A;  3KRA A;  5DHK A;  4KPD A;  3OYR A;  3P8R A;  5I1U A;  2ZCR A;  3EZ3 A;  5B00 A;  2Z52 A;  5B0J A;  3WEG A;  4OKZ A;  3WCG A;  5JA0 F;  5HN7 A;  2AEL A;  1YYR A;  5IK0 A;  3M9U A;  3WCA A;  4F6X A;  1YHM A;  3N0G A;  5EAS A;  2E8T A;  3VJ8 A;  3ICM A;  4DWB A;  2ZCQ A;  3M01 A;  5AHU B;  4DZW A;  5JUZ F;  3N5J F;  1V4H A;  5H9D A;  3RMG A;  2Q80 A;  3N6K F;  1EZF A;  1HM7 A;  4GAX A;  4EA0 A;  1YYU A;  1V4K A;  4E9U A;  3LOM A;  4ZQ8 A;  1FPS A;  3WE9 A;  3LMD A;  3ZMB A;  3W7F A;  5EAT A;  3WSB A;  5IMP A;  2AEK A;  4LOB A;  4DWG A;  3WC9 A;  2J1P A;  4H5D F;  4P0W A;  5HNA A;  1HX9 A;  3KRP A;  2H8O A;  3KRF A;  4EA1 A;  2Z4X A;  3APZ A;  5IK6 A;  2E8V A;  4E1E A;  4F6V A;  3Q30 A;  2VF6 A;  2Z4Z A;  3WJK A;  3WCB A;  2AZJ A;  3KRO B;  3WEF A;  3OAC A;  3ZOU A;  4KKM A;  4JXN A;  3QQV A;  5ILK A;  5B0M A;  5DJR F;  2P1C A;  1N24 A;  3LLW A;  3ZL6 A;  3NRI A;  1JFA A;  2E8X A;  3WEK A;  3SDT A;  5DW7 A;  1RQI A;  5AYP A;  3VJA A;  3WEH A;  2E94 A;  5DJP F;  4LPG F;  5DJV F;  2Q9Z A;  3OAB A;  5ILI A;  1RTR A;  3P5R A;  2AZK A;  4F62 A;  3ACX A;  5EAU A;  4OMG A;  3SDQ A;  3KRC B;  2OPM A;  4RXA A;  3TFN A;  2ZCS A;  3B7L A;  3WCL A;  2E8U A;  3M0G A;  1KIZ A;  2FTZ A;  4KVY A;  5JV0 F;  4OKM A;  3AQB B;  1JFG A;  1YYQ A;  4LA5 A;  4UMJ A;  3CC9 A;  4HD1 A;  4LFG A;  3WCI A;  1HM4 A;  1DGP A;  3ADZ A;  3WJN A;  4KQ5 A;  4LPH F;  2Q58 A;  4NFI F;  3WCC A;  1WY0 A;  4H5C F;  3WEJ A;  1KIY A;  1V4E A;  3LSN A;  5CG6 A;  3PDE A;  3KRC A;  2ZY1 A;  1UBW A;  4MC8 A;  3DYG A;  2J1O A;  1V4J A;  4LUU A;  3P8L A;  2F89 F;  4JYX A;  3SDU A;  5DHI A;  3KB9 A;  2J5C A;  3KRP B;  2RAH A;  5IMI A;  3KRF B;  5ILD A;  5IVG A;  2F94 F;  5ERO A;  3V1V A;  3N5H F;  1DI1 A;  4KQS A;  4QPF A;  3LEE A;  4NKF A;  5ILJ A;  2PS4 A;  4LZ0 A;  5AFX A;  4LZC A;  5DGN F;  3AQC B;  3Q1O A;  3RYE A;  4L2X F;  4GP1 A;  3WCM A;  5ILY A;  3OAC B;  4NKE A;  1VG6 A;  3QKC A;  5DGM F;  1N23 A;  4KVI A;  2Z7H A;  3M02 A;  5B02 A;  4RXD A;  2E93 A;  3AQ0 A;  2OPN A;  4KUX A;  4N1Z F;  5IKH A;  4GA3 A;  4KWD A;  5A0I A;  1WL2 A;  1HXC A;  4H5E F;  3PYB A;  4LXW A;  1YYT A;  3LK5 A;  3IBA A;  4RXE A;  3LJI A;  3N0F A;  2Q9Y A;  3OAB B;  3TFV A;  2ONH A;  3UCA A;  1UBY A;  1VG7 A;  3SDV A;  1YYS A;  4WK5 A;  5A0K A;  2ZCO A;  3N1V F;  3N3L F;  5B0I A;  4JZB A;  2I19 A;  3LG5 A;  3G4D A;  4MC0 A;  2AZL A;  2EWG A;  2QIS A;  2E8W A;  3N3D A;  5IK9 A;  2ZEV A;  4K10 A;  5E8H A;  3MZV A;  2PS5 A;  5HN8 A;  3ACW A;  2E4O A;  2ZEU A;  3LZ9 A;  3CKE A;  3VJB A;  1WL1 A;  3V1X A;  5B03 A;  3BNY A;  3IPI A;  2OA6 A;  1VG2 A;  5ERM A;  4LZ3 A;  3S9V A;  5C05 A;  3ICN A;  4EA2 A;  1YV5 A;  5B0K A;  5ER8 A;  3WCE A;  5IN8 A;  1N20 A;  3NF2 A;  4LLT A;  3P41 A;  4DI5 A;  1VG4 A;  3TS7 A;  1VG3 A;  1HXG A;  1YHL A;  1HXA A;  4JXY A;  1N22 A;  5E8K A;  3TFP A;  4KQU A;  4RNQ A;  3V66 A;  3N1W F;  4Q23 A;  4PVX F;  3AE0 A;  1ZW5 A;  4RXC A;  4NFK F;  4N9U A;  3RBM A;  3LGK A;  3BNX A;  2Z4Y A;  4GP2 A;  2Z7I A;  3SAE A;  1UBV A;  2E91 A;  2O1O A;  5ERN A;  5HN9 A;  4LFV F;  1YJ4 A;  3PKO A;  5ILH A;  3Q2Q A;  4P0X A;  5IL8 A;  4LFE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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