4Q23A

The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates
Total Genus 136
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
341
structure length
337
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKAAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title The role of threonine 201 and tyrosine 204 in the human farnesyl pyrophosphate synthase catalytic mechanism and the mode of inhibition by the nitrogen-containing bisphosphonates
rcsb
source organism Homo sapiens
total genus 136
structure length 337
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2014-04-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 4q23A00
1FPSA 4XQTF 1HX9A 5B01A 1RTRA 4DHDA 3SAEA 1EZFA 3NPKA 4P0WA 2ONHA 3LOMA 3G4DA 4NKEA 3OACA 3RYEA 4OMGA 5ILJA 3ZMBA 3N6KF 5IK9A 2RAHA 2AELA 3WC9A 5EASA 3LZ9A 5B0MA 3P41A 3CKEA 1V4HA 3KBKA 5E8LA 3TS7A 1JFAA 3M02A 4WK5A 3VJDA 4NKFA 2DH4A 2EWGA 4NUAA 3EGTA 3MZVA 2Z4VA 3AQ0A 5CG6A 2I19A 2OA6A 4OGUA 3B7LA 3RBMA 2Z4YA 3KROA 5AFXA 5IMPA 5DHKA 3M00A 3WJOA 3LGKA 3OABA 4LXWA 4DWBA 1YHKA 5HN9A 3RYWA 1YHMA 2F7MF 2Q9ZA 5HN7A 5B0KA 3ADZA 4NFIF 4JVJF 1YYUA 5ILHA 2F94F 5IMNA 2FTZA 4KVWA 1RQIA 4JXNA 5DJVF 2E95A 3WEFA 4ZQ8A 5CG5A 2PS6A 5IM1A 4RXAA 2OPMA 3S9VA 4H5DF 1YQ7A 3WCJA 5KSXF 5DGNF 5DHIA 3M01A 2Q58A 4GA3A 5I1UA 2ZCOA 1YYTA 4E9ZA 3LMDA 2OGDA 2Z4ZA 3AQBB 3WEIA 3MAVA 2Z7HA 5JV1F 1YV5A 1DGPA 3WCBA 3WCDA 3PDEA 1N22A 3BNXA 3N49F 3N0FA 3N45F 3QQVA 3PYAA 1VG4A 2E8UA 4DXJA 5HNAA 4K10A 4LTZA 2P1CA 5ER8A 3NF2A 2PS7A 5DIQF 1WKZA 2E8XA 2AETA 5IK6A 3N5JF 3WCHA 4NG6A 4PVYF 3OABB 4KPJA 2Z4XA 1WL1A 3N0GA 2ZY1A 3P8RA 3VJ8A 4MC3A 5IKAA 3IBAA 4XQSF 3PH7A 4LA5A 5ERMA 4E1EA 1N24A 1KIYA 4LZ0A 4PVXF 1PS1A 4LFGA 1YYSA 3PKOA 4FP4A 3WCGA 3NRIA 5ILZA 2Z50A 3OYRA 4GP2A 4LIXA 5AHUB 5ILDA 1JFGA 5A0KA 2ZEUA 3WJNA 2Q80A 1VG7A 3DYHA 3AE0A 1HXCA 4KVDA 5HN8A 2H8OA 1DI1A 4RNQA 5IL3A 3ICMA 2PS5A 1HM4A 3LDWA 5EAUA 3EZ3A 4H5EF 3ICNA 3WEHA 4H5CF 4KWDA 5JUZF 1V4IA 2VF6A 1KIZA 3TFNA 3W7FA 1VG3A 5B02A 1WL2A 2AZJA 3KRAB 4KVYA 2F9KF 3WE9A 4KKMA 2F8CF 3N3LF 3WCMA 2E8TA 4F6VA 1N20A 5A0IA 3LJIA 3PYBA 3TFPA 3V1XA 5JV0F 2J5CA 3DYFA 4N1ZF 5DW7A 3RMGA 5B0LA 5H9DA 5EROA 4DI5A 3CC9A 3LLWA 3M0GA 2E91A 4JXYA 2ZCRA 3ICKA 1V4EA 4LLSA 4OMHA 2ZCQA 3WCIA 1WL0A 3ID0A 4EA1A 3DYGA 5DJRF 4XQRF 3V66A 1VG6A 3NPRA 3P8LA 3LG5A 1UBVA 2Q9YA 5B03A 3N46F 2ZCSA 4KQUA 1YHLA 3M9UA 3G4FA 1HM7A 2Z4WA 3KRAA 3SDQA 2AEKA 2E93A 4JZBA 4E9UA 3N3DA 3WCLA 3VJEA 3WCFA 4KPDA 5A0JA 5JA0F 4NFKF 3QKCA 3KRPA 4RXDA 1V4KA 3EFQA 5IVGA 3ACYA 1YJ4A 2ONGA 4LLTA 4N9UA 4RXCA 3ACWA 2F8ZF 5ILIA 2O1OA 4EA0A 5DJPF 4L2XF 5JV2F 1YYRA 1UBYA 5AELA 1HXGA 4JYXA 3Q30A 4KQSA 1N1BA 2Z78A 2ZEVA 1V4JA 4OKMA 4GAXA 3LVSA 3TFVA 1UBXA 4KFAA 3APZA 4KQ5A 5IKHA 3WSBA 3P5RA 3N5HF 4UMJA 4LFEA 4DEMF 3Q2ZA 3N1VF 4F6XA 3S4JA 3VJ9A 2E90A 3WCCA 1WL3A 4F62A 3LSNA 2PS8A 5ILYA 1WY0A 5DZ2A 5IMIA 3SDRA 4KK2A 4RYPA 5B00A 2F92F 3VJCA 2OPNA 3LGZB 1YYQA 5B0JA 3KRCA 4LUUA 3VJAA 3UCAA 4OKZA 4LPGF 3ZL6A 3ACXA 3KRFB 3WCAA 3ZCDA 3KRPB 4FJQA 4DWGA 3SDVA 3LEEA 3TC1A 3BNYA 4HD1A 5E8KA 1WMWA 4DZWA 2Z7IA 3WSAA 3Q1OA 3WCEA 2E94A 4RXEA 4EA2A 3ZOUA 3AQCB 3SDUA 3WEGA 2E8WA 3Q2QA 3CP6A 3WEJA 5B0IA 4LTVA 4JZXA 3VJBA 3V1VA 4QXSF 3LK5A 3P5PA 2Z52A 1VG2A 5DGMF 4LA6A 4P0XA 2E8VA 2J1PA 4GP1A 3OACB 5ILKA 1HXAA 4LFVF 1RQJA 2E92A 2AZKA 3ASXA 1N23A 4P0VA 4KVIA 4NFJF 4LZCA 5IL8A 3WEKA 2AZLA 5ERNA 2E4OA 3N1WF 3KRFA 2QISA 4LZ3A 5EATA 4KUXA 4MC0A 3KB9A 2PS4A 5AYPA 3ICZA 5IK0A 5IN8A 1ZW5A 1N1ZA 5E8HA 3SDTA 5C05A 4LPHF 5DGSF 2F89F 4QPFA 3ZMCA 2J1OA 4LOBA 3KROB 3IPIA 2FORA 3KRCB 4MC8A 1UBWA 1N21A 3WJKA 4Q23A
chains in the Genus database with same CATH superfamily
1FPSA 4XQTF 1HX9A 5B01A 1RTRA 4DHDA 3SAEA 1EZFA 3NPKA 4P0WA 2ONHA 3LOMA 3G4DA 4NKEA 3OACA 3RYEA 4OMGA 5ILJA 3ZMBA 3N6KF 5IK9A 2RAHA 2AELA 3WC9A 5EASA 3LZ9A 5B0MA 3P41A 3CKEA 1V4HA 3KBKA 5E8LA 3TS7A 1JFAA 3M02A 4WK5A 3VJDA 4NKFA 2DH4A 2EWGA 4NUAA 3EGTA 3MZVA 2Z4VA 3AQ0A 5CG6A 2I19A 2OA6A 4OGUA 3B7LA 3RBMA 2Z4YA 3KROA 5AFXA 5IMPA 5DHKA 3M00A 3WJOA 3LGKA 3OABA 4LXWA 4DWBA 1YHKA 5HN9A 3RYWA 1YHMA 2F7MF 2Q9ZA 5HN7A 5B0KA 3ADZA 4NFIF 4JVJF 1YYUA 5ILHA 2F94F 5IMNA 2FTZA 4KVWA 1RQIA 4JXNA 5DJVF 2E95A 3WEFA 4ZQ8A 5CG5A 2PS6A 5IM1A 4RXAA 2OPMA 3S9VA 4H5DF 1YQ7A 3WCJA 5KSXF 5DGNF 5DHIA 3M01A 2Q58A 4GA3A 5I1UA 2ZCOA 1YYTA 4E9ZA 3LMDA 2OGDA 2Z4ZA 3AQBB 3WEIA 3MAVA 2Z7HA 5JV1F 1YV5A 1DGPA 3WCBA 3WCDA 3PDEA 1N22A 3BNXA 3N49F 3N0FA 3N45F 3QQVA 3PYAA 1VG4A 2E8UA 4DXJA 5HNAA 4K10A 4LTZA 2P1CA 5ER8A 3NF2A 2PS7A 5DIQF 1WKZA 2E8XA 2AETA 5IK6A 3N5JF 3WCHA 4NG6A 4PVYF 3OABB 4KPJA 2Z4XA 1WL1A 3N0GA 2ZY1A 3P8RA 3VJ8A 4MC3A 5IKAA 3IBAA 4XQSF 3PH7A 4LA5A 5ERMA 4E1EA 1N24A 1KIYA 4LZ0A 4PVXF 1PS1A 4LFGA 1YYSA 3PKOA 4FP4A 3WCGA 3NRIA 5ILZA 2Z50A 3OYRA 4GP2A 4LIXA 5AHUB 5ILDA 1JFGA 5A0KA 2ZEUA 3WJNA 2Q80A 1VG7A 3DYHA 3AE0A 1HXCA 4KVDA 5HN8A 2H8OA 1DI1A 4RNQA 5IL3A 3ICMA 2PS5A 1HM4A 3LDWA 5EAUA 3EZ3A 4H5EF 3ICNA 3WEHA 4H5CF 4KWDA 5JUZF 1V4IA 2VF6A 1KIZA 3TFNA 3W7FA 1VG3A 5B02A 1WL2A 2AZJA 3KRAB 4KVYA 2F9KF 3WE9A 4KKMA 2F8CF 3N3LF 3WCMA 2E8TA 4F6VA 1N20A 5A0IA 3LJIA 3PYBA 3TFPA 3V1XA 5JV0F 2J5CA 3DYFA 4N1ZF 5DW7A 3RMGA 5B0LA 5H9DA 5EROA 4DI5A 3CC9A 3LLWA 3M0GA 2E91A 4JXYA 2ZCRA 3ICKA 1V4EA 4LLSA 4OMHA 2ZCQA 3WCIA 1WL0A 3ID0A 4EA1A 3DYGA 5DJRF 4XQRF 3V66A 1VG6A 3NPRA 3P8LA 3LG5A 1UBVA 2Q9YA 5B03A 3N46F 2ZCSA 4KQUA 1YHLA 3M9UA 3G4FA 1HM7A 2Z4WA 3KRAA 3SDQA 2AEKA 2E93A 4JZBA 4E9UA 3N3DA 3WCLA 3VJEA 3WCFA 4KPDA 5A0JA 5JA0F 4NFKF 3QKCA 3KRPA 4RXDA 1V4KA 3EFQA 5IVGA 3ACYA 1YJ4A 2ONGA 4LLTA 4N9UA 4RXCA 3ACWA 2F8ZF 5ILIA 2O1OA 4EA0A 5DJPF 4L2XF 5JV2F 1YYRA 1UBYA 5AELA 1HXGA 4JYXA 3Q30A 4KQSA 1N1BA 2Z78A 2ZEVA 1V4JA 4OKMA 4GAXA 3LVSA 3TFVA 1UBXA 4KFAA 3APZA 4KQ5A 5IKHA 3WSBA 3P5RA 3N5HF 4UMJA 4LFEA 4DEMF 3Q2ZA 3N1VF 4F6XA 3S4JA 3VJ9A 2E90A 3WCCA 1WL3A 4F62A 3LSNA 2PS8A 5ILYA 1WY0A 5DZ2A 5IMIA 3SDRA 4KK2A 4RYPA 5B00A 2F92F 3VJCA 2OPNA 3LGZB 1YYQA 5B0JA 3KRCA 4LUUA 3VJAA 3UCAA 4OKZA 4LPGF 3ZL6A 3ACXA 3KRFB 3WCAA 3ZCDA 3KRPB 4FJQA 4DWGA 3SDVA 3LEEA 3TC1A 3BNYA 4HD1A 5E8KA 1WMWA 4DZWA 2Z7IA 3WSAA 3Q1OA 3WCEA 2E94A 4RXEA 4EA2A 3ZOUA 3AQCB 3SDUA 3WEGA 2E8WA 3Q2QA 3CP6A 3WEJA 5B0IA 4LTVA 4JZXA 3VJBA 3V1VA 4QXSF 3LK5A 3P5PA 2Z52A 1VG2A 5DGMF 4LA6A 4P0XA 2E8VA 2J1PA 4GP1A 3OACB 5ILKA 1HXAA 4LFVF 1RQJA 2E92A 2AZKA 3ASXA 1N23A 4P0VA 4KVIA 4NFJF 4LZCA 5IL8A 3WEKA 2AZLA 5ERNA 2E4OA 3N1WF 3KRFA 2QISA 4LZ3A 5EATA 4KUXA 4MC0A 3KB9A 2PS4A 5AYPA 3ICZA 5IK0A 5IN8A 1ZW5A 1N1ZA 5E8HA 3SDTA 5C05A 4LPHF 5DGSF 2F89F 4QPFA 3ZMCA 2J1OA 4LOBA 3KROB 3IPIA 2FORA 3KRCB 4MC8A 1UBWA 1N21A 3WJKA 4Q23A
chains in the Genus database with same CATH topology
1FPSA 4XQTF 1HX9A 5B01A 1RTRA 4DHDA 3SAEA 1EZFA 3NPKA 4P0WA 2ONHA 3LOMA 3G4DA 4NKEA 3OACA 3RYEA 4OMGA 5ILJA 3ZMBA 3N6KF 5IK9A 2RAHA 2AELA 3WC9A 5EASA 3LZ9A 5B0MA 3P41A 3CKEA 1V4HA 3KBKA 5E8LA 3TS7A 1JFAA 3M02A 4WK5A 3VJDA 4NKFA 2DH4A 2EWGA 4NUAA 3EGTA 3MZVA 2Z4VA 3AQ0A 5CG6A 2I19A 2OA6A 4OGUA 3B7LA 3RBMA 2Z4YA 3KROA 5AFXA 5IMPA 5DHKA 3M00A 3WJOA 3LGKA 3OABA 4LXWA 4DWBA 1YHKA 5HN9A 3RYWA 1YHMA 2F7MF 2Q9ZA 5HN7A 5B0KA 3ADZA 4NFIF 4JVJF 1YYUA 5ILHA 2F94F 5IMNA 2FTZA 4KVWA 1RQIA 4JXNA 5DJVF 2E95A 3WEFA 4ZQ8A 5CG5A 2PS6A 5IM1A 4RXAA 2OPMA 3S9VA 4H5DF 1YQ7A 3WCJA 5KSXF 5DGNF 5DHIA 3M01A 2Q58A 4GA3A 5I1UA 2ZCOA 1YYTA 4E9ZA 3LMDA 2OGDA 2Z4ZA 3AQBB 3WEIA 3MAVA 2Z7HA 5JV1F 1YV5A 1DGPA 3WCBA 3WCDA 3PDEA 1N22A 3BNXA 3N49F 3N0FA 3N45F 3QQVA 3PYAA 1VG4A 2E8UA 4DXJA 5HNAA 4K10A 4LTZA 2P1CA 5ER8A 3NF2A 2PS7A 5DIQF 1WKZA 2E8XA 2AETA 5IK6A 3N5JF 3WCHA 4NG6A 4PVYF 3OABB 4KPJA 2Z4XA 1WL1A 3N0GA 2ZY1A 3P8RA 3VJ8A 4MC3A 5IKAA 3IBAA 4XQSF 3PH7A 4LA5A 5ERMA 4E1EA 1N24A 1KIYA 4LZ0A 4PVXF 1PS1A 4LFGA 1YYSA 3PKOA 4FP4A 3WCGA 3NRIA 5ILZA 2Z50A 3OYRA 4GP2A 4LIXA 5AHUB 5ILDA 1JFGA 5A0KA 2ZEUA 3WJNA 2Q80A 1VG7A 3DYHA 3AE0A 1HXCA 4KVDA 5HN8A 2H8OA 1DI1A 4RNQA 5IL3A 3ICMA 2PS5A 1HM4A 3LDWA 5EAUA 3EZ3A 4H5EF 3ICNA 3WEHA 4H5CF 4KWDA 5JUZF 1V4IA 2VF6A 1KIZA 3TFNA 3W7FA 1VG3A 5B02A 1WL2A 2AZJA 3KRAB 4KVYA 2F9KF 3WE9A 4KKMA 2F8CF 3N3LF 3WCMA 2E8TA 4F6VA 1N20A 5A0IA 3LJIA 3PYBA 3TFPA 3V1XA 5JV0F 2J5CA 3DYFA 4N1ZF 5DW7A 3RMGA 5B0LA 5H9DA 5EROA 4DI5A 3CC9A 3LLWA 3M0GA 2E91A 4JXYA 2ZCRA 3ICKA 1V4EA 4LLSA 4OMHA 2ZCQA 3WCIA 1WL0A 3ID0A 4EA1A 3DYGA 5DJRF 4XQRF 3V66A 1VG6A 3NPRA 3P8LA 3LG5A 1UBVA 2Q9YA 5B03A 3N46F 2ZCSA 4KQUA 1YHLA 3M9UA 3G4FA 1HM7A 2Z4WA 3KRAA 3SDQA 2AEKA 2E93A 4JZBA 4E9UA 3N3DA 3WCLA 3VJEA 3WCFA 4KPDA 5A0JA 5JA0F 4NFKF 3QKCA 3KRPA 4RXDA 1V4KA 3EFQA 5IVGA 3ACYA 1YJ4A 2ONGA 4LLTA 4N9UA 4RXCA 3ACWA 2F8ZF 5ILIA 2O1OA 4EA0A 5DJPF 4L2XF 5JV2F 1YYRA 1UBYA 5AELA 1HXGA 4JYXA 3Q30A 4KQSA 1N1BA 2Z78A 2ZEVA 1V4JA 4OKMA 4GAXA 3LVSA 3TFVA 1UBXA 4KFAA 3APZA 4KQ5A 5IKHA 3WSBA 3P5RA 3N5HF 4UMJA 4LFEA 4DEMF 3Q2ZA 3N1VF 4F6XA 3S4JA 3VJ9A 2E90A 3WCCA 1WL3A 4F62A 3LSNA 2PS8A 5ILYA 1WY0A 5DZ2A 5IMIA 3SDRA 4KK2A 4RYPA 5B00A 2F92F 3VJCA 2OPNA 3LGZB 1YYQA 5B0JA 3KRCA 4LUUA 3VJAA 3UCAA 4OKZA 4LPGF 3ZL6A 3ACXA 3KRFB 3WCAA 3ZCDA 3KRPB 4FJQA 4DWGA 3SDVA 3LEEA 3TC1A 3BNYA 4HD1A 5E8KA 1WMWA 4DZWA 2Z7IA 3WSAA 3Q1OA 3WCEA 2E94A 4RXEA 4EA2A 3ZOUA 3AQCB 3SDUA 3WEGA 2E8WA 3Q2QA 3CP6A 3WEJA 5B0IA 4LTVA 4JZXA 3VJBA 3V1VA 4QXSF 3LK5A 3P5PA 2Z52A 1VG2A 5DGMF 4LA6A 4P0XA 2E8VA 2J1PA 4GP1A 3OACB 5ILKA 1HXAA 4LFVF 1RQJA 2E92A 2AZKA 3ASXA 1N23A 4P0VA 4KVIA 4NFJF 4LZCA 5IL8A 3WEKA 2AZLA 5ERNA 2E4OA 3N1WF 3KRFA 2QISA 4LZ3A 5EATA 4KUXA 4MC0A 3KB9A 2PS4A 5AYPA 3ICZA 5IK0A 5IN8A 1ZW5A 1N1ZA 5E8HA 3SDTA 5C05A 4LPHF 5DGSF 2F89F 4QPFA 3ZMCA 2J1OA 4LOBA 3KROB 3IPIA 2FORA 3KRCB 4MC8A 1UBWA 1N21A 3WJKA 4Q23A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FPS A;  4XQT F;  1HX9 A;  5B01 A;  1RTR A;  4DHD A;  3SAE A;  1EZF A;  3NPK A;  4P0W A;  2ONH A;  3LOM A;  3G4D A;  4NKE A;  3OAC A;  3RYE A;  4OMG A;  5ILJ A;  3ZMB A;  3N6K F;  5IK9 A;  2RAH A;  2AEL A;  3WC9 A;  5EAS A;  3LZ9 A;  5B0M A;  3P41 A;  3CKE A;  1V4H A;  3KBK A;  5E8L A;  3TS7 A;  1JFA A;  3M02 A;  4WK5 A;  3VJD A;  4NKF A;  2DH4 A;  2EWG A;  4NUA A;  3EGT A;  3MZV A;  2Z4V A;  3AQ0 A;  5CG6 A;  2I19 A;  2OA6 A;  4OGU A;  3B7L A;  3RBM A;  2Z4Y A;  3KRO A;  5AFX A;  5IMP A;  5DHK A;  3M00 A;  3WJO A;  3LGK A;  3OAB A;  4LXW A;  4DWB A;  1YHK A;  5HN9 A;  3RYW A;  1YHM A;  2F7M F;  2Q9Z A;  5HN7 A;  5B0K A;  3ADZ A;  4NFI F;  4JVJ F;  1YYU A;  5ILH A;  2F94 F;  5IMN A;  2FTZ A;  4KVW A;  1RQI A;  4JXN A;  5DJV F;  2E95 A;  3WEF A;  4ZQ8 A;  5CG5 A;  2PS6 A;  5IM1 A;  4RXA A;  2OPM A;  3S9V A;  4H5D F;  1YQ7 A;  3WCJ A;  5KSX F;  5DGN F;  5DHI A;  3M01 A;  2Q58 A;  4GA3 A;  5I1U A;  2ZCO A;  1YYT A;  4E9Z A;  3LMD A;  2OGD A;  2Z4Z A;  3AQB B;  3WEI A;  3MAV A;  2Z7H A;  5JV1 F;  1YV5 A;  1DGP A;  3WCB A;  3WCD A;  3PDE A;  1N22 A;  3BNX A;  3N49 F;  3N0F A;  3N45 F;  3QQV A;  3PYA A;  1VG4 A;  2E8U A;  4DXJ A;  5HNA A;  4K10 A;  4LTZ A;  2P1C A;  5ER8 A;  3NF2 A;  2PS7 A;  5DIQ F;  1WKZ A;  2E8X A;  2AET A;  5IK6 A;  3N5J F;  3WCH A;  4NG6 A;  4PVY F;  3OAB B;  4KPJ A;  2Z4X A;  1WL1 A;  3N0G A;  2ZY1 A;  3P8R A;  3VJ8 A;  4MC3 A;  5IKA A;  3IBA A;  4XQS F;  3PH7 A;  4LA5 A;  5ERM A;  4E1E A;  1N24 A;  1KIY A;  4LZ0 A;  4PVX F;  1PS1 A;  4LFG A;  1YYS A;  3PKO A;  4FP4 A;  3WCG A;  3NRI A;  5ILZ A;  2Z50 A;  3OYR A;  4GP2 A;  4LIX A;  5AHU B;  5ILD A;  1JFG A;  5A0K A;  2ZEU A;  3WJN A;  2Q80 A;  1VG7 A;  3DYH A;  3AE0 A;  1HXC A;  4KVD A;  5HN8 A;  2H8O A;  1DI1 A;  4RNQ A;  5IL3 A;  3ICM A;  2PS5 A;  1HM4 A;  3LDW A;  5EAU A;  3EZ3 A;  4H5E F;  3ICN A;  3WEH A;  4H5C F;  4KWD A;  5JUZ F;  1V4I A;  2VF6 A;  1KIZ A;  3TFN A;  3W7F A;  1VG3 A;  5B02 A;  1WL2 A;  2AZJ A;  3KRA B;  4KVY A;  2F9K F;  3WE9 A;  4KKM A;  2F8C F;  3N3L F;  3WCM A;  2E8T A;  4F6V A;  1N20 A;  5A0I A;  3LJI A;  3PYB A;  3TFP A;  3V1X A;  5JV0 F;  2J5C A;  3DYF A;  4N1Z F;  5DW7 A;  3RMG A;  5B0L A;  5H9D A;  5ERO A;  4DI5 A;  3CC9 A;  3LLW A;  3M0G A;  2E91 A;  4JXY A;  2ZCR A;  3ICK A;  1V4E A;  4LLS A;  4OMH A;  2ZCQ A;  3WCI A;  1WL0 A;  3ID0 A;  4EA1 A;  3DYG A;  5DJR F;  4XQR F;  3V66 A;  1VG6 A;  3NPR A;  3P8L A;  3LG5 A;  1UBV A;  2Q9Y A;  5B03 A;  3N46 F;  2ZCS A;  4KQU A;  1YHL A;  3M9U A;  3G4F A;  1HM7 A;  2Z4W A;  3KRA A;  3SDQ A;  2AEK A;  2E93 A;  4JZB A;  4E9U A;  3N3D A;  3WCL A;  3VJE A;  3WCF A;  4KPD A;  5A0J A;  5JA0 F;  4NFK F;  3QKC A;  3KRP A;  4RXD A;  1V4K A;  3EFQ A;  5IVG A;  3ACY A;  1YJ4 A;  2ONG A;  4LLT A;  4N9U A;  4RXC A;  3ACW A;  2F8Z F;  5ILI A;  2O1O A;  4EA0 A;  5DJP F;  4L2X F;  5JV2 F;  1YYR A;  1UBY A;  5AEL A;  1HXG A;  4JYX A;  3Q30 A;  4KQS A;  1N1B A;  2Z78 A;  2ZEV A;  1V4J A;  4OKM A;  4GAX A;  3LVS A;  3TFV A;  1UBX A;  4KFA A;  3APZ A;  4KQ5 A;  5IKH A;  3WSB A;  3P5R A;  3N5H F;  4UMJ A;  4LFE A;  4DEM F;  3Q2Z A;  3N1V F;  4F6X A;  3S4J A;  3VJ9 A;  2E90 A;  3WCC A;  1WL3 A;  4F62 A;  3LSN A;  2PS8 A;  5ILY A;  1WY0 A;  5DZ2 A;  5IMI A;  3SDR A;  4KK2 A;  4RYP A;  5B00 A;  2F92 F;  3VJC A;  2OPN A;  3LGZ B;  1YYQ A;  5B0J A;  3KRC A;  4LUU A;  3VJA A;  3UCA A;  4OKZ A;  4LPG F;  3ZL6 A;  3ACX A;  3KRF B;  3WCA A;  3ZCD A;  3KRP B;  4FJQ A;  4DWG A;  3SDV A;  3LEE A;  3TC1 A;  3BNY A;  4HD1 A;  5E8K A;  1WMW A;  4DZW A;  2Z7I A;  3WSA A;  3Q1O A;  3WCE A;  2E94 A;  4RXE A;  4EA2 A;  3ZOU A;  3AQC B;  3SDU A;  3WEG A;  2E8W A;  3Q2Q A;  3CP6 A;  3WEJ A;  5B0I A;  4LTV A;  4JZX A;  3VJB A;  3V1V A;  4QXS F;  3LK5 A;  3P5P A;  2Z52 A;  1VG2 A;  5DGM F;  4LA6 A;  4P0X A;  2E8V A;  2J1P A;  4GP1 A;  3OAC B;  5ILK A;  1HXA A;  4LFV F;  1RQJ A;  2E92 A;  2AZK A;  3ASX A;  1N23 A;  4P0V A;  4KVI A;  4NFJ F;  4LZC A;  5IL8 A;  3WEK A;  2AZL A;  5ERN A;  2E4O A;  3N1W F;  3KRF A;  2QIS A;  4LZ3 A;  5EAT A;  4KUX A;  4MC0 A;  3KB9 A;  2PS4 A;  5AYP A;  3ICZ A;  5IK0 A;  5IN8 A;  1ZW5 A;  1N1Z A;  5E8H A;  3SDT A;  5C05 A;  4LPH F;  5DGS F;  2F89 F;  4QPF A;  3ZMC A;  2J1O A;  4LOB A;  3KRO B;  3IPI A;  2FOR A;  3KRC B;  4MC8 A;  1UBW A;  1N21 A;  3WJK A;  4Q23 A; 
#chains in the Genus database with same CATH topology
 1FPS A;  4XQT F;  1HX9 A;  5B01 A;  1RTR A;  4DHD A;  3SAE A;  1EZF A;  3NPK A;  4P0W A;  2ONH A;  3LOM A;  3G4D A;  4NKE A;  3OAC A;  3RYE A;  4OMG A;  5ILJ A;  3ZMB A;  3N6K F;  5IK9 A;  2RAH A;  2AEL A;  3WC9 A;  5EAS A;  3LZ9 A;  5B0M A;  3P41 A;  3CKE A;  1V4H A;  3KBK A;  5E8L A;  3TS7 A;  1JFA A;  3M02 A;  4WK5 A;  3VJD A;  4NKF A;  2DH4 A;  2EWG A;  4NUA A;  3EGT A;  3MZV A;  2Z4V A;  3AQ0 A;  5CG6 A;  2I19 A;  2OA6 A;  4OGU A;  3B7L A;  3RBM A;  2Z4Y A;  3KRO A;  5AFX A;  5IMP A;  5DHK A;  3M00 A;  3WJO A;  3LGK A;  3OAB A;  4LXW A;  4DWB A;  1YHK A;  5HN9 A;  3RYW A;  1YHM A;  2F7M F;  2Q9Z A;  5HN7 A;  5B0K A;  3ADZ A;  4NFI F;  4JVJ F;  1YYU A;  5ILH A;  2F94 F;  5IMN A;  2FTZ A;  4KVW A;  1RQI A;  4JXN A;  5DJV F;  2E95 A;  3WEF A;  4ZQ8 A;  5CG5 A;  2PS6 A;  5IM1 A;  4RXA A;  2OPM A;  3S9V A;  4H5D F;  1YQ7 A;  3WCJ A;  5KSX F;  5DGN F;  5DHI A;  3M01 A;  2Q58 A;  4GA3 A;  5I1U A;  2ZCO A;  1YYT A;  4E9Z A;  3LMD A;  2OGD A;  2Z4Z A;  3AQB B;  3WEI A;  3MAV A;  2Z7H A;  5JV1 F;  1YV5 A;  1DGP A;  3WCB A;  3WCD A;  3PDE A;  1N22 A;  3BNX A;  3N49 F;  3N0F A;  3N45 F;  3QQV A;  3PYA A;  1VG4 A;  2E8U A;  4DXJ A;  5HNA A;  4K10 A;  4LTZ A;  2P1C A;  5ER8 A;  3NF2 A;  2PS7 A;  5DIQ F;  1WKZ A;  2E8X A;  2AET A;  5IK6 A;  3N5J F;  3WCH A;  4NG6 A;  4PVY F;  3OAB B;  4KPJ A;  2Z4X A;  1WL1 A;  3N0G A;  2ZY1 A;  3P8R A;  3VJ8 A;  4MC3 A;  5IKA A;  3IBA A;  4XQS F;  3PH7 A;  4LA5 A;  5ERM A;  4E1E A;  1N24 A;  1KIY A;  4LZ0 A;  4PVX F;  1PS1 A;  4LFG A;  1YYS A;  3PKO A;  4FP4 A;  3WCG A;  3NRI A;  5ILZ A;  2Z50 A;  3OYR A;  4GP2 A;  4LIX A;  5AHU B;  5ILD A;  1JFG A;  5A0K A;  2ZEU A;  3WJN A;  2Q80 A;  1VG7 A;  3DYH A;  3AE0 A;  1HXC A;  4KVD A;  5HN8 A;  2H8O A;  1DI1 A;  4RNQ A;  5IL3 A;  3ICM A;  2PS5 A;  1HM4 A;  3LDW A;  5EAU A;  3EZ3 A;  4H5E F;  3ICN A;  3WEH A;  4H5C F;  4KWD A;  5JUZ F;  1V4I A;  2VF6 A;  1KIZ A;  3TFN A;  3W7F A;  1VG3 A;  5B02 A;  1WL2 A;  2AZJ A;  3KRA B;  4KVY A;  2F9K F;  3WE9 A;  4KKM A;  2F8C F;  3N3L F;  3WCM A;  2E8T A;  4F6V A;  1N20 A;  5A0I A;  3LJI A;  3PYB A;  3TFP A;  3V1X A;  5JV0 F;  2J5C A;  3DYF A;  4N1Z F;  5DW7 A;  3RMG A;  5B0L A;  5H9D A;  5ERO A;  4DI5 A;  3CC9 A;  3LLW A;  3M0G A;  2E91 A;  4JXY A;  2ZCR A;  3ICK A;  1V4E A;  4LLS A;  4OMH A;  2ZCQ A;  3WCI A;  1WL0 A;  3ID0 A;  4EA1 A;  3DYG A;  5DJR F;  4XQR F;  3V66 A;  1VG6 A;  3NPR A;  3P8L A;  3LG5 A;  1UBV A;  2Q9Y A;  5B03 A;  3N46 F;  2ZCS A;  4KQU A;  1YHL A;  3M9U A;  3G4F A;  1HM7 A;  2Z4W A;  3KRA A;  3SDQ A;  2AEK A;  2E93 A;  4JZB A;  4E9U A;  3N3D A;  3WCL A;  3VJE A;  3WCF A;  4KPD A;  5A0J A;  5JA0 F;  4NFK F;  3QKC A;  3KRP A;  4RXD A;  1V4K A;  3EFQ A;  5IVG A;  3ACY A;  1YJ4 A;  2ONG A;  4LLT A;  4N9U A;  4RXC A;  3ACW A;  2F8Z F;  5ILI A;  2O1O A;  4EA0 A;  5DJP F;  4L2X F;  5JV2 F;  1YYR A;  1UBY A;  5AEL A;  1HXG A;  4JYX A;  3Q30 A;  4KQS A;  1N1B A;  2Z78 A;  2ZEV A;  1V4J A;  4OKM A;  4GAX A;  3LVS A;  3TFV A;  1UBX A;  4KFA A;  3APZ A;  4KQ5 A;  5IKH A;  3WSB A;  3P5R A;  3N5H F;  4UMJ A;  4LFE A;  4DEM F;  3Q2Z A;  3N1V F;  4F6X A;  3S4J A;  3VJ9 A;  2E90 A;  3WCC A;  1WL3 A;  4F62 A;  3LSN A;  2PS8 A;  5ILY A;  1WY0 A;  5DZ2 A;  5IMI A;  3SDR A;  4KK2 A;  4RYP A;  5B00 A;  2F92 F;  3VJC A;  2OPN A;  3LGZ B;  1YYQ A;  5B0J A;  3KRC A;  4LUU A;  3VJA A;  3UCA A;  4OKZ A;  4LPG F;  3ZL6 A;  3ACX A;  3KRF B;  3WCA A;  3ZCD A;  3KRP B;  4FJQ A;  4DWG A;  3SDV A;  3LEE A;  3TC1 A;  3BNY A;  4HD1 A;  5E8K A;  1WMW A;  4DZW A;  2Z7I A;  3WSA A;  3Q1O A;  3WCE A;  2E94 A;  4RXE A;  4EA2 A;  3ZOU A;  3AQC B;  3SDU A;  3WEG A;  2E8W A;  3Q2Q A;  3CP6 A;  3WEJ A;  5B0I A;  4LTV A;  4JZX A;  3VJB A;  3V1V A;  4QXS F;  3LK5 A;  3P5P A;  2Z52 A;  1VG2 A;  5DGM F;  4LA6 A;  4P0X A;  2E8V A;  2J1P A;  4GP1 A;  3OAC B;  5ILK A;  1HXA A;  4LFV F;  1RQJ A;  2E92 A;  2AZK A;  3ASX A;  1N23 A;  4P0V A;  4KVI A;  4NFJ F;  4LZC A;  5IL8 A;  3WEK A;  2AZL A;  5ERN A;  2E4O A;  3N1W F;  3KRF A;  2QIS A;  4LZ3 A;  5EAT A;  4KUX A;  4MC0 A;  3KB9 A;  2PS4 A;  5AYP A;  3ICZ A;  5IK0 A;  5IN8 A;  1ZW5 A;  1N1Z A;  5E8H A;  3SDT A;  5C05 A;  4LPH F;  5DGS F;  2F89 F;  4QPF A;  3ZMC A;  2J1O A;  4LOB A;  3KRO B;  3IPI A;  2FOR A;  3KRC B;  4MC8 A;  1UBW A;  1N21 A;  3WJK A;  4Q23 A; 
#chains in the Genus database with same CATH homology
 1FPS A;  4XQT F;  1HX9 A;  5B01 A;  1RTR A;  4DHD A;  3SAE A;  1EZF A;  3NPK A;  4P0W A;  2ONH A;  3LOM A;  3G4D A;  4NKE A;  3OAC A;  3RYE A;  4OMG A;  5ILJ A;  3ZMB A;  3N6K F;  5IK9 A;  2RAH A;  2AEL A;  3WC9 A;  5EAS A;  3LZ9 A;  5B0M A;  3P41 A;  3CKE A;  1V4H A;  3KBK A;  5E8L A;  3TS7 A;  1JFA A;  3M02 A;  4WK5 A;  3VJD A;  4NKF A;  2DH4 A;  2EWG A;  4NUA A;  3EGT A;  3MZV A;  2Z4V A;  3AQ0 A;  5CG6 A;  2I19 A;  2OA6 A;  4OGU A;  3B7L A;  3RBM A;  2Z4Y A;  3KRO A;  5AFX A;  5IMP A;  5DHK A;  3M00 A;  3WJO A;  3LGK A;  3OAB A;  4LXW A;  4DWB A;  1YHK A;  5HN9 A;  3RYW A;  1YHM A;  2F7M F;  2Q9Z A;  5HN7 A;  5B0K A;  3ADZ A;  4NFI F;  4JVJ F;  1YYU A;  5ILH A;  2F94 F;  5IMN A;  2FTZ A;  4KVW A;  1RQI A;  4JXN A;  5DJV F;  2E95 A;  3WEF A;  4ZQ8 A;  5CG5 A;  2PS6 A;  5IM1 A;  4RXA A;  2OPM A;  3S9V A;  4H5D F;  1YQ7 A;  3WCJ A;  5KSX F;  5DGN F;  5DHI A;  3M01 A;  2Q58 A;  4GA3 A;  5I1U A;  2ZCO A;  1YYT A;  4E9Z A;  3LMD A;  2OGD A;  2Z4Z A;  3AQB B;  3WEI A;  3MAV A;  2Z7H A;  5JV1 F;  1YV5 A;  1DGP A;  3WCB A;  3WCD A;  3PDE A;  1N22 A;  3BNX A;  3N49 F;  3N0F A;  3N45 F;  3QQV A;  3PYA A;  1VG4 A;  2E8U A;  4DXJ A;  5HNA A;  4K10 A;  4LTZ A;  2P1C A;  5ER8 A;  3NF2 A;  2PS7 A;  5DIQ F;  1WKZ A;  2E8X A;  2AET A;  5IK6 A;  3N5J F;  3WCH A;  4NG6 A;  4PVY F;  3OAB B;  4KPJ A;  2Z4X A;  1WL1 A;  3N0G A;  2ZY1 A;  3P8R A;  3VJ8 A;  4MC3 A;  5IKA A;  3IBA A;  4XQS F;  3PH7 A;  4LA5 A;  5ERM A;  4E1E A;  1N24 A;  1KIY A;  4LZ0 A;  4PVX F;  1PS1 A;  4LFG A;  1YYS A;  3PKO A;  4FP4 A;  3WCG A;  3NRI A;  5ILZ A;  2Z50 A;  3OYR A;  4GP2 A;  4LIX A;  5AHU B;  5ILD A;  1JFG A;  5A0K A;  2ZEU A;  3WJN A;  2Q80 A;  1VG7 A;  3DYH A;  3AE0 A;  1HXC A;  4KVD A;  5HN8 A;  2H8O A;  1DI1 A;  4RNQ A;  5IL3 A;  3ICM A;  2PS5 A;  1HM4 A;  3LDW A;  5EAU A;  3EZ3 A;  4H5E F;  3ICN A;  3WEH A;  4H5C F;  4KWD A;  5JUZ F;  1V4I A;  2VF6 A;  1KIZ A;  3TFN A;  3W7F A;  1VG3 A;  5B02 A;  1WL2 A;  2AZJ A;  3KRA B;  4KVY A;  2F9K F;  3WE9 A;  4KKM A;  2F8C F;  3N3L F;  3WCM A;  2E8T A;  4F6V A;  1N20 A;  5A0I A;  3LJI A;  3PYB A;  3TFP A;  3V1X A;  5JV0 F;  2J5C A;  3DYF A;  4N1Z F;  5DW7 A;  3RMG A;  5B0L A;  5H9D A;  5ERO A;  4DI5 A;  3CC9 A;  3LLW A;  3M0G A;  2E91 A;  4JXY A;  2ZCR A;  3ICK A;  1V4E A;  4LLS A;  4OMH A;  2ZCQ A;  3WCI A;  1WL0 A;  3ID0 A;  4EA1 A;  3DYG A;  5DJR F;  4XQR F;  3V66 A;  1VG6 A;  3NPR A;  3P8L A;  3LG5 A;  1UBV A;  2Q9Y A;  5B03 A;  3N46 F;  2ZCS A;  4KQU A;  1YHL A;  3M9U A;  3G4F A;  1HM7 A;  2Z4W A;  3KRA A;  3SDQ A;  2AEK A;  2E93 A;  4JZB A;  4E9U A;  3N3D A;  3WCL A;  3VJE A;  3WCF A;  4KPD A;  5A0J A;  5JA0 F;  4NFK F;  3QKC A;  3KRP A;  4RXD A;  1V4K A;  3EFQ A;  5IVG A;  3ACY A;  1YJ4 A;  2ONG A;  4LLT A;  4N9U A;  4RXC A;  3ACW A;  2F8Z F;  5ILI A;  2O1O A;  4EA0 A;  5DJP F;  4L2X F;  5JV2 F;  1YYR A;  1UBY A;  5AEL A;  1HXG A;  4JYX A;  3Q30 A;  4KQS A;  1N1B A;  2Z78 A;  2ZEV A;  1V4J A;  4OKM A;  4GAX A;  3LVS A;  3TFV A;  1UBX A;  4KFA A;  3APZ A;  4KQ5 A;  5IKH A;  3WSB A;  3P5R A;  3N5H F;  4UMJ A;  4LFE A;  4DEM F;  3Q2Z A;  3N1V F;  4F6X A;  3S4J A;  3VJ9 A;  2E90 A;  3WCC A;  1WL3 A;  4F62 A;  3LSN A;  2PS8 A;  5ILY A;  1WY0 A;  5DZ2 A;  5IMI A;  3SDR A;  4KK2 A;  4RYP A;  5B00 A;  2F92 F;  3VJC A;  2OPN A;  3LGZ B;  1YYQ A;  5B0J A;  3KRC A;  4LUU A;  3VJA A;  3UCA A;  4OKZ A;  4LPG F;  3ZL6 A;  3ACX A;  3KRF B;  3WCA A;  3ZCD A;  3KRP B;  4FJQ A;  4DWG A;  3SDV A;  3LEE A;  3TC1 A;  3BNY A;  4HD1 A;  5E8K A;  1WMW A;  4DZW A;  2Z7I A;  3WSA A;  3Q1O A;  3WCE A;  2E94 A;  4RXE A;  4EA2 A;  3ZOU A;  3AQC B;  3SDU A;  3WEG A;  2E8W A;  3Q2Q A;  3CP6 A;  3WEJ A;  5B0I A;  4LTV A;  4JZX A;  3VJB A;  3V1V A;  4QXS F;  3LK5 A;  3P5P A;  2Z52 A;  1VG2 A;  5DGM F;  4LA6 A;  4P0X A;  2E8V A;  2J1P A;  4GP1 A;  3OAC B;  5ILK A;  1HXA A;  4LFV F;  1RQJ A;  2E92 A;  2AZK A;  3ASX A;  1N23 A;  4P0V A;  4KVI A;  4NFJ F;  4LZC A;  5IL8 A;  3WEK A;  2AZL A;  5ERN A;  2E4O A;  3N1W F;  3KRF A;  2QIS A;  4LZ3 A;  5EAT A;  4KUX A;  4MC0 A;  3KB9 A;  2PS4 A;  5AYP A;  3ICZ A;  5IK0 A;  5IN8 A;  1ZW5 A;  1N1Z A;  5E8H A;  3SDT A;  5C05 A;  4LPH F;  5DGS F;  2F89 F;  4QPF A;  3ZMC A;  2J1O A;  4LOB A;  3KRO B;  3IPI A;  2FOR A;  3KRC B;  4MC8 A;  1UBW A;  1N21 A;  3WJK A;  4Q23 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...