2F9KF

Crystal structure of human fpps in complex with zoledronate and zn2+
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl Diphosphate Synthase
publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 137
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f9kF00
1YV5A 1N24A 3DYHA 2AETA 4H5DF 4RYPA 3NRIA 3V1XA 3N46F 4QPFA 3ICNA 2Z4ZA 3P8RA 3KRFB 3TFNA 4JYXA 4DEMF 5AHUB 5ILYA 2H8OA 5IVGA 3CC9A 5DHIA 4NG6A 3RYWA 3LLWA 3KRAB 3QQVA 3SAEA 2FTZA 1VG2A 1FPSA 2E8TA 3LGZB 3P8LA 4RXCA 4LZCA 2O1OA 3VJ8A 5DJRF 4WK5A 4DZWA 4LOBA 3VJEA 3KRAA 4KQSA 3WJKA 1N23A 4RXEA 5IL3A 5EATA 5IK6A 1V4JA 4MC0A 3PDEA 4LUUA 3NF2A 3OABA 1YQ7A 2ONGA 4LTVA 5ILZA 3WCDA 3WJNA 4DWBA 1UBVA 3ICZA 3ASXA 3M01A 2F92F 1RQJA 2Q9ZA 2FORA 4NUAA 5B00A 4LLSA 3S4JA 3N6KF 4KFAA 5DHKA 2ZCOA 3VJAA 2PS6A 3SDVA 4KVDA 4MC8A 1V4KA 2E8UA 3V66A 2F89F 2E8XA 1KIZA 3EGTA 5JV0F 4KUXA 4H5EF 4LFVF 4OKZA 4NFJF 4KQ5A 3WCHA 3V1VA 1HM7A 2Z4VA 4LTZA 3N1VF 5ER8A 2Z7IA 4L2XF 5DJVF 3WCEA 3WEJA 3WCMA 3PYBA 2PS7A 2ZCQA 5AYPA 5EAUA 3W7FA 5ERMA 5ILHA 3ZMCA 5B0LA 3WEGA 5DGSF 2PS4A 4P0WA 3LSNA 5B0MA 4N1ZF 5EASA 3WEKA 5IKAA 3Q1OA 3N5HF 4P0XA 3TS7A 3WSBA 3LEEA 3PKOA 3KRCB 4LFEA 2Z4XA 1HM4A 4K10A 4QXSF 4P0VA 3WE9A 3VJBA 3WCAA 5IMIA 3WEIA 2E8WA 3WSAA 2AZJA 1WL2A 3WCFA 1VG6A 1HXGA 4JZBA 3G4DA 2Q80A 3S9VA 3WCGA 1UBXA 4KVYA 2ZEVA 3WEFA 3Q2QA 3EZ3A 1DGPA 3AQ0A 3ZL6A 3ICKA 2E94A 1VG7A 4JVJF 1JFAA 3CP6A 5B02A 3Q30A 2F94F 3KRFA 2Q58A 4PVYF 3QKCA 3VJCA 1N20A 4NKEA 4OGUA 4E1EA 3M0GA 2VF6A 4HD1A 3B7LA 1HXCA 3ZCDA 5I1UA 4LPGF 3NPRA 3BNXA 3SDQA 1JFGA 5DW7A 2OPNA 3ZMBA 4KWDA 5JA0F 3SDRA 3RYEA 4GAXA 3EFQA 4JXNA 3APZA 2Q9YA 3ID0A 4FJQA 3WCLA 4LPHF 5E8KA 4JZXA 2F8ZF 1WL1A 2ZCRA 3IBAA 4LLTA 4H5CF 5AFXA 3VJ9A 3KBKA 4KK2A 2ZEUA 5DGNF 2AELA 3AE0A 3KRPB 1WL3A 4RXAA 4N9UA 1YHLA 3LDWA 4RNQA 3IPIA 3WEHA 3ICMA 5E8LA 3ACWA 3N45F 2RAHA 5A0KA 1WKZA 2Z7HA 3KRPA 3N5JF 1HXAA 3DYGA 2E4OA 5B0JA 2ZCSA 4LXWA 3VJDA 2P1CA 2J1OA 3MAVA 3TC1A 5JV2F 1YYSA 2F7MF 4NKFA 1KIYA 5DIQF 1WL0A 3P41A 4MC3A 4OKMA 5EROA 3LGKA 2F8CF 5B0IA 5IM1A 3WCCA 5B03A 5IMNA 2E92A 4KVIA 5DJPF 2ONHA 3OYRA 4F6VA 4F6XA 1V4HA 3ACYA 1YYUA 3M02A 3N0FA 3LMDA 4JXYA 3WCIA 4GP1A 3LG5A 2E8VA 3OACB 4DI5A 1V4EA 3M9UA 4DXJA 1EZFA 2J5CA 2AEKA 1VG4A 3WCJA 3KRCA 1YHKA 3ADZA 1DI1A 1N21A 5HN7A 5B0KA 4KVWA 2AZKA 2E91A 3OACA 3N1WF 4LIXA 4Q23A 4LZ0A 5B01A 2OGDA 4NFKF 3PYAA 3RBMA 3N3LF 1YYTA 5CG5A 4XQRF 4LZ3A 4E9UA 5JUZF 2AZLA 1YYRA 5IN8A 5IL8A 5CG6A 1YHMA 2E95A 5DGMF 1RTRA 4LA6A 3UCAA 4OMGA 5DZ2A 2OA6A 4EA2A 5IK0A 4KPJA 3PH7A 5ILDA 2EWGA 3ZOUA 1WMWA 4GP2A 1PS1A 1V4IA 5ERNA 4OMHA 2F9KF 5E8HA 1N1BA 3N3DA 4F62A 2Z4YA 4XQTF 1N22A 3WC9A 3OABB 4LA5A 4PVXF 3AQCB 3LZ9A 5IKHA 2DH4A 2Z4WA 4KKMA 1ZW5A 3BNYA 4EA0A 2QISA 3G4FA 3LK5A 4UMJA 2ZY1A 5ILIA 5JV1F 1N1ZA 3DYFA 4ZQ8A 3Q2ZA 3SDTA 5ILKA 3M00A 5AELA 3LJIA 4DHDA 1UBYA 2Z52A 4E9ZA 2E90A 2OPMA 3NPKA 3TFPA 3AQBB 4DWGA 4NFIF 3MZVA 4GA3A 1YJ4A 5ILJA 5C05A 1RQIA 3KROB 5IMPA 4KQUA 3WCBA 3SDUA 5IK9A 3P5RA 4KPDA 5HNAA 2Z78A 2J1PA 3LOMA 3LVSA 1WY0A 5KSXF 3WJOA 3KROA 3P5PA 1HX9A 5HN8A 4XQSF 5H9DA 3ACXA 1VG3A 2E93A 4RXDA 3CKEA 4FP4A 3N0GA 2PS5A 3KB9A 2Z50A 4EA1A 2I19A 2PS8A 3TFVA 5A0IA 3N49F 5A0JA 5HN9A 3RMGA 1UBWA 4LFGA 1YYQA
chains in the Genus database with same CATH superfamily
1YV5A 1N24A 3DYHA 2AETA 4H5DF 4RYPA 3NRIA 3V1XA 3N46F 4QPFA 3ICNA 2Z4ZA 3P8RA 3KRFB 3TFNA 4JYXA 4DEMF 5AHUB 5ILYA 2H8OA 5IVGA 3CC9A 5DHIA 4NG6A 3RYWA 3LLWA 3KRAB 3QQVA 3SAEA 2FTZA 1VG2A 1FPSA 2E8TA 3LGZB 3P8LA 4RXCA 4LZCA 2O1OA 3VJ8A 5DJRF 4WK5A 4DZWA 4LOBA 3VJEA 3KRAA 4KQSA 3WJKA 1N23A 4RXEA 5IL3A 5EATA 5IK6A 1V4JA 4MC0A 3PDEA 4LUUA 3NF2A 3OABA 1YQ7A 2ONGA 4LTVA 5ILZA 3WCDA 3WJNA 4DWBA 1UBVA 3ICZA 3ASXA 3M01A 2F92F 1RQJA 2Q9ZA 2FORA 4NUAA 5B00A 4LLSA 3S4JA 3N6KF 4KFAA 5DHKA 2ZCOA 3VJAA 2PS6A 3SDVA 4KVDA 4MC8A 1V4KA 2E8UA 3V66A 2F89F 2E8XA 1KIZA 3EGTA 5JV0F 4KUXA 4H5EF 4LFVF 4OKZA 4NFJF 4KQ5A 3WCHA 3V1VA 1HM7A 2Z4VA 4LTZA 3N1VF 5ER8A 2Z7IA 4L2XF 5DJVF 3WCEA 3WEJA 3WCMA 3PYBA 2PS7A 2ZCQA 5AYPA 5EAUA 3W7FA 5ERMA 5ILHA 3ZMCA 5B0LA 3WEGA 5DGSF 2PS4A 4P0WA 3LSNA 5B0MA 4N1ZF 5EASA 3WEKA 5IKAA 3Q1OA 3N5HF 4P0XA 3TS7A 3WSBA 3LEEA 3PKOA 3KRCB 4LFEA 2Z4XA 1HM4A 4K10A 4QXSF 4P0VA 3WE9A 3VJBA 3WCAA 5IMIA 3WEIA 2E8WA 3WSAA 2AZJA 1WL2A 3WCFA 1VG6A 1HXGA 4JZBA 3G4DA 2Q80A 3S9VA 3WCGA 1UBXA 4KVYA 2ZEVA 3WEFA 3Q2QA 3EZ3A 1DGPA 3AQ0A 3ZL6A 3ICKA 2E94A 1VG7A 4JVJF 1JFAA 3CP6A 5B02A 3Q30A 2F94F 3KRFA 2Q58A 4PVYF 3QKCA 3VJCA 1N20A 4NKEA 4OGUA 4E1EA 3M0GA 2VF6A 4HD1A 3B7LA 1HXCA 3ZCDA 5I1UA 4LPGF 3NPRA 3BNXA 3SDQA 1JFGA 5DW7A 2OPNA 3ZMBA 4KWDA 5JA0F 3SDRA 3RYEA 4GAXA 3EFQA 4JXNA 3APZA 2Q9YA 3ID0A 4FJQA 3WCLA 4LPHF 5E8KA 4JZXA 2F8ZF 1WL1A 2ZCRA 3IBAA 4LLTA 4H5CF 5AFXA 3VJ9A 3KBKA 4KK2A 2ZEUA 5DGNF 2AELA 3AE0A 3KRPB 1WL3A 4RXAA 4N9UA 1YHLA 3LDWA 4RNQA 3IPIA 3WEHA 3ICMA 5E8LA 3ACWA 3N45F 2RAHA 5A0KA 1WKZA 2Z7HA 3KRPA 3N5JF 1HXAA 3DYGA 2E4OA 5B0JA 2ZCSA 4LXWA 3VJDA 2P1CA 2J1OA 3MAVA 3TC1A 5JV2F 1YYSA 2F7MF 4NKFA 1KIYA 5DIQF 1WL0A 3P41A 4MC3A 4OKMA 5EROA 3LGKA 2F8CF 5B0IA 5IM1A 3WCCA 5B03A 5IMNA 2E92A 4KVIA 5DJPF 2ONHA 3OYRA 4F6VA 4F6XA 1V4HA 3ACYA 1YYUA 3M02A 3N0FA 3LMDA 4JXYA 3WCIA 4GP1A 3LG5A 2E8VA 3OACB 4DI5A 1V4EA 3M9UA 4DXJA 1EZFA 2J5CA 2AEKA 1VG4A 3WCJA 3KRCA 1YHKA 3ADZA 1DI1A 1N21A 5HN7A 5B0KA 4KVWA 2AZKA 2E91A 3OACA 3N1WF 4LIXA 4Q23A 4LZ0A 5B01A 2OGDA 4NFKF 3PYAA 3RBMA 3N3LF 1YYTA 5CG5A 4XQRF 4LZ3A 4E9UA 5JUZF 2AZLA 1YYRA 5IN8A 5IL8A 5CG6A 1YHMA 2E95A 5DGMF 1RTRA 4LA6A 3UCAA 4OMGA 5DZ2A 2OA6A 4EA2A 5IK0A 4KPJA 3PH7A 5ILDA 2EWGA 3ZOUA 1WMWA 4GP2A 1PS1A 1V4IA 5ERNA 4OMHA 2F9KF 5E8HA 1N1BA 3N3DA 4F62A 2Z4YA 4XQTF 1N22A 3WC9A 3OABB 4LA5A 4PVXF 3AQCB 3LZ9A 5IKHA 2DH4A 2Z4WA 4KKMA 1ZW5A 3BNYA 4EA0A 2QISA 3G4FA 3LK5A 4UMJA 2ZY1A 5ILIA 5JV1F 1N1ZA 3DYFA 4ZQ8A 3Q2ZA 3SDTA 5ILKA 3M00A 5AELA 3LJIA 4DHDA 1UBYA 2Z52A 4E9ZA 2E90A 2OPMA 3NPKA 3TFPA 3AQBB 4DWGA 4NFIF 3MZVA 4GA3A 1YJ4A 5ILJA 5C05A 1RQIA 3KROB 5IMPA 4KQUA 3WCBA 3SDUA 5IK9A 3P5RA 4KPDA 5HNAA 2Z78A 2J1PA 3LOMA 3LVSA 1WY0A 5KSXF 3WJOA 3KROA 3P5PA 1HX9A 5HN8A 4XQSF 5H9DA 3ACXA 1VG3A 2E93A 4RXDA 3CKEA 4FP4A 3N0GA 2PS5A 3KB9A 2Z50A 4EA1A 2I19A 2PS8A 3TFVA 5A0IA 3N49F 5A0JA 5HN9A 3RMGA 1UBWA 4LFGA 1YYQA
chains in the Genus database with same CATH topology
1YV5A 1N24A 3DYHA 2AETA 4H5DF 4RYPA 3NRIA 3V1XA 3N46F 4QPFA 3ICNA 2Z4ZA 3P8RA 3KRFB 3TFNA 4JYXA 4DEMF 5AHUB 5ILYA 2H8OA 5IVGA 3CC9A 5DHIA 4NG6A 3RYWA 3LLWA 3KRAB 3QQVA 3SAEA 2FTZA 1VG2A 1FPSA 2E8TA 3LGZB 3P8LA 4RXCA 4LZCA 2O1OA 3VJ8A 5DJRF 4WK5A 4DZWA 4LOBA 3VJEA 3KRAA 4KQSA 3WJKA 1N23A 4RXEA 5IL3A 5EATA 5IK6A 1V4JA 4MC0A 3PDEA 4LUUA 3NF2A 3OABA 1YQ7A 2ONGA 4LTVA 5ILZA 3WCDA 3WJNA 4DWBA 1UBVA 3ICZA 3ASXA 3M01A 2F92F 1RQJA 2Q9ZA 2FORA 4NUAA 5B00A 4LLSA 3S4JA 3N6KF 4KFAA 5DHKA 2ZCOA 3VJAA 2PS6A 3SDVA 4KVDA 4MC8A 1V4KA 2E8UA 3V66A 2F89F 2E8XA 1KIZA 3EGTA 5JV0F 4KUXA 4H5EF 4LFVF 4OKZA 4NFJF 4KQ5A 3WCHA 3V1VA 1HM7A 2Z4VA 4LTZA 3N1VF 5ER8A 2Z7IA 4L2XF 5DJVF 3WCEA 3WEJA 3WCMA 3PYBA 2PS7A 2ZCQA 5AYPA 5EAUA 3W7FA 5ERMA 5ILHA 3ZMCA 5B0LA 3WEGA 5DGSF 2PS4A 4P0WA 3LSNA 5B0MA 4N1ZF 5EASA 3WEKA 5IKAA 3Q1OA 3N5HF 4P0XA 3TS7A 3WSBA 3LEEA 3PKOA 3KRCB 4LFEA 2Z4XA 1HM4A 4K10A 4QXSF 4P0VA 3WE9A 3VJBA 3WCAA 5IMIA 3WEIA 2E8WA 3WSAA 2AZJA 1WL2A 3WCFA 1VG6A 1HXGA 4JZBA 3G4DA 2Q80A 3S9VA 3WCGA 1UBXA 4KVYA 2ZEVA 3WEFA 3Q2QA 3EZ3A 1DGPA 3AQ0A 3ZL6A 3ICKA 2E94A 1VG7A 4JVJF 1JFAA 3CP6A 5B02A 3Q30A 2F94F 3KRFA 2Q58A 4PVYF 3QKCA 3VJCA 1N20A 4NKEA 4OGUA 4E1EA 3M0GA 2VF6A 4HD1A 3B7LA 1HXCA 3ZCDA 5I1UA 4LPGF 3NPRA 3BNXA 3SDQA 1JFGA 5DW7A 2OPNA 3ZMBA 4KWDA 5JA0F 3SDRA 3RYEA 4GAXA 3EFQA 4JXNA 3APZA 2Q9YA 3ID0A 4FJQA 3WCLA 4LPHF 5E8KA 4JZXA 2F8ZF 1WL1A 2ZCRA 3IBAA 4LLTA 4H5CF 5AFXA 3VJ9A 3KBKA 4KK2A 2ZEUA 5DGNF 2AELA 3AE0A 3KRPB 1WL3A 4RXAA 4N9UA 1YHLA 3LDWA 4RNQA 3IPIA 3WEHA 3ICMA 5E8LA 3ACWA 3N45F 2RAHA 5A0KA 1WKZA 2Z7HA 3KRPA 3N5JF 1HXAA 3DYGA 2E4OA 5B0JA 2ZCSA 4LXWA 3VJDA 2P1CA 2J1OA 3MAVA 3TC1A 5JV2F 1YYSA 2F7MF 4NKFA 1KIYA 5DIQF 1WL0A 3P41A 4MC3A 4OKMA 5EROA 3LGKA 2F8CF 5B0IA 5IM1A 3WCCA 5B03A 5IMNA 2E92A 4KVIA 5DJPF 2ONHA 3OYRA 4F6VA 4F6XA 1V4HA 3ACYA 1YYUA 3M02A 3N0FA 3LMDA 4JXYA 3WCIA 4GP1A 3LG5A 2E8VA 3OACB 4DI5A 1V4EA 3M9UA 4DXJA 1EZFA 2J5CA 2AEKA 1VG4A 3WCJA 3KRCA 1YHKA 3ADZA 1DI1A 1N21A 5HN7A 5B0KA 4KVWA 2AZKA 2E91A 3OACA 3N1WF 4LIXA 4Q23A 4LZ0A 5B01A 2OGDA 4NFKF 3PYAA 3RBMA 3N3LF 1YYTA 5CG5A 4XQRF 4LZ3A 4E9UA 5JUZF 2AZLA 1YYRA 5IN8A 5IL8A 5CG6A 1YHMA 2E95A 5DGMF 1RTRA 4LA6A 3UCAA 4OMGA 5DZ2A 2OA6A 4EA2A 5IK0A 4KPJA 3PH7A 5ILDA 2EWGA 3ZOUA 1WMWA 4GP2A 1PS1A 1V4IA 5ERNA 4OMHA 2F9KF 5E8HA 1N1BA 3N3DA 4F62A 2Z4YA 4XQTF 1N22A 3WC9A 3OABB 4LA5A 4PVXF 3AQCB 3LZ9A 5IKHA 2DH4A 2Z4WA 4KKMA 1ZW5A 3BNYA 4EA0A 2QISA 3G4FA 3LK5A 4UMJA 2ZY1A 5ILIA 5JV1F 1N1ZA 3DYFA 4ZQ8A 3Q2ZA 3SDTA 5ILKA 3M00A 5AELA 3LJIA 4DHDA 1UBYA 2Z52A 4E9ZA 2E90A 2OPMA 3NPKA 3TFPA 3AQBB 4DWGA 4NFIF 3MZVA 4GA3A 1YJ4A 5ILJA 5C05A 1RQIA 3KROB 5IMPA 4KQUA 3WCBA 3SDUA 5IK9A 3P5RA 4KPDA 5HNAA 2Z78A 2J1PA 3LOMA 3LVSA 1WY0A 5KSXF 3WJOA 3KROA 3P5PA 1HX9A 5HN8A 4XQSF 5H9DA 3ACXA 1VG3A 2E93A 4RXDA 3CKEA 4FP4A 3N0GA 2PS5A 3KB9A 2Z50A 4EA1A 2I19A 2PS8A 3TFVA 5A0IA 3N49F 5A0JA 5HN9A 3RMGA 1UBWA 4LFGA 1YYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YV5 A;  1N24 A;  3DYH A;  2AET A;  4H5D F;  4RYP A;  3NRI A;  3V1X A;  3N46 F;  4QPF A;  3ICN A;  2Z4Z A;  3P8R A;  3KRF B;  3TFN A;  4JYX A;  4DEM F;  5AHU B;  5ILY A;  2H8O A;  5IVG A;  3CC9 A;  5DHI A;  4NG6 A;  3RYW A;  3LLW A;  3KRA B;  3QQV A;  3SAE A;  2FTZ A;  1VG2 A;  1FPS A;  2E8T A;  3LGZ B;  3P8L A;  4RXC A;  4LZC A;  2O1O A;  3VJ8 A;  5DJR F;  4WK5 A;  4DZW A;  4LOB A;  3VJE A;  3KRA A;  4KQS A;  3WJK A;  1N23 A;  4RXE A;  5IL3 A;  5EAT A;  5IK6 A;  1V4J A;  4MC0 A;  3PDE A;  4LUU A;  3NF2 A;  3OAB A;  1YQ7 A;  2ONG A;  4LTV A;  5ILZ A;  3WCD A;  3WJN A;  4DWB A;  1UBV A;  3ICZ A;  3ASX A;  3M01 A;  2F92 F;  1RQJ A;  2Q9Z A;  2FOR A;  4NUA A;  5B00 A;  4LLS A;  3S4J A;  3N6K F;  4KFA A;  5DHK A;  2ZCO A;  3VJA A;  2PS6 A;  3SDV A;  4KVD A;  4MC8 A;  1V4K A;  2E8U A;  3V66 A;  2F89 F;  2E8X A;  1KIZ A;  3EGT A;  5JV0 F;  4KUX A;  4H5E F;  4LFV F;  4OKZ A;  4NFJ F;  4KQ5 A;  3WCH A;  3V1V A;  1HM7 A;  2Z4V A;  4LTZ A;  3N1V F;  5ER8 A;  2Z7I A;  4L2X F;  5DJV F;  3WCE A;  3WEJ A;  3WCM A;  3PYB A;  2PS7 A;  2ZCQ A;  5AYP A;  5EAU A;  3W7F A;  5ERM A;  5ILH A;  3ZMC A;  5B0L A;  3WEG A;  5DGS F;  2PS4 A;  4P0W A;  3LSN A;  5B0M A;  4N1Z F;  5EAS A;  3WEK A;  5IKA A;  3Q1O A;  3N5H F;  4P0X A;  3TS7 A;  3WSB A;  3LEE A;  3PKO A;  3KRC B;  4LFE A;  2Z4X A;  1HM4 A;  4K10 A;  4QXS F;  4P0V A;  3WE9 A;  3VJB A;  3WCA A;  5IMI A;  3WEI A;  2E8W A;  3WSA A;  2AZJ A;  1WL2 A;  3WCF A;  1VG6 A;  1HXG A;  4JZB A;  3G4D A;  2Q80 A;  3S9V A;  3WCG A;  1UBX A;  4KVY A;  2ZEV A;  3WEF A;  3Q2Q A;  3EZ3 A;  1DGP A;  3AQ0 A;  3ZL6 A;  3ICK A;  2E94 A;  1VG7 A;  4JVJ F;  1JFA A;  3CP6 A;  5B02 A;  3Q30 A;  2F94 F;  3KRF A;  2Q58 A;  4PVY F;  3QKC A;  3VJC A;  1N20 A;  4NKE A;  4OGU A;  4E1E A;  3M0G A;  2VF6 A;  4HD1 A;  3B7L A;  1HXC A;  3ZCD A;  5I1U A;  4LPG F;  3NPR A;  3BNX A;  3SDQ A;  1JFG A;  5DW7 A;  2OPN A;  3ZMB A;  4KWD A;  5JA0 F;  3SDR A;  3RYE A;  4GAX A;  3EFQ A;  4JXN A;  3APZ A;  2Q9Y A;  3ID0 A;  4FJQ A;  3WCL A;  4LPH F;  5E8K A;  4JZX A;  2F8Z F;  1WL1 A;  2ZCR A;  3IBA A;  4LLT A;  4H5C F;  5AFX A;  3VJ9 A;  3KBK A;  4KK2 A;  2ZEU A;  5DGN F;  2AEL A;  3AE0 A;  3KRP B;  1WL3 A;  4RXA A;  4N9U A;  1YHL A;  3LDW A;  4RNQ A;  3IPI A;  3WEH A;  3ICM A;  5E8L A;  3ACW A;  3N45 F;  2RAH A;  5A0K A;  1WKZ A;  2Z7H A;  3KRP A;  3N5J F;  1HXA A;  3DYG A;  2E4O A;  5B0J A;  2ZCS A;  4LXW A;  3VJD A;  2P1C A;  2J1O A;  3MAV A;  3TC1 A;  5JV2 F;  1YYS A;  2F7M F;  4NKF A;  1KIY A;  5DIQ F;  1WL0 A;  3P41 A;  4MC3 A;  4OKM A;  5ERO A;  3LGK A;  2F8C F;  5B0I A;  5IM1 A;  3WCC A;  5B03 A;  5IMN A;  2E92 A;  4KVI A;  5DJP F;  2ONH A;  3OYR A;  4F6V A;  4F6X A;  1V4H A;  3ACY A;  1YYU A;  3M02 A;  3N0F A;  3LMD A;  4JXY A;  3WCI A;  4GP1 A;  3LG5 A;  2E8V A;  3OAC B;  4DI5 A;  1V4E A;  3M9U A;  4DXJ A;  1EZF A;  2J5C A;  2AEK A;  1VG4 A;  3WCJ A;  3KRC A;  1YHK A;  3ADZ A;  1DI1 A;  1N21 A;  5HN7 A;  5B0K A;  4KVW A;  2AZK A;  2E91 A;  3OAC A;  3N1W F;  4LIX A;  4Q23 A;  4LZ0 A;  5B01 A;  2OGD A;  4NFK F;  3PYA A;  3RBM A;  3N3L F;  1YYT A;  5CG5 A;  4XQR F;  4LZ3 A;  4E9U A;  5JUZ F;  2AZL A;  1YYR A;  5IN8 A;  5IL8 A;  5CG6 A;  1YHM A;  2E95 A;  5DGM F;  1RTR A;  4LA6 A;  3UCA A;  4OMG A;  5DZ2 A;  2OA6 A;  4EA2 A;  5IK0 A;  4KPJ A;  3PH7 A;  5ILD A;  2EWG A;  3ZOU A;  1WMW A;  4GP2 A;  1PS1 A;  1V4I A;  5ERN A;  4OMH A;  2F9K F;  5E8H A;  1N1B A;  3N3D A;  4F62 A;  2Z4Y A;  4XQT F;  1N22 A;  3WC9 A;  3OAB B;  4LA5 A;  4PVX F;  3AQC B;  3LZ9 A;  5IKH A;  2DH4 A;  2Z4W A;  4KKM A;  1ZW5 A;  3BNY A;  4EA0 A;  2QIS A;  3G4F A;  3LK5 A;  4UMJ A;  2ZY1 A;  5ILI A;  5JV1 F;  1N1Z A;  3DYF A;  4ZQ8 A;  3Q2Z A;  3SDT A;  5ILK A;  3M00 A;  5AEL A;  3LJI A;  4DHD A;  1UBY A;  2Z52 A;  4E9Z A;  2E90 A;  2OPM A;  3NPK A;  3TFP A;  3AQB B;  4DWG A;  4NFI F;  3MZV A;  4GA3 A;  1YJ4 A;  5ILJ A;  5C05 A;  1RQI A;  3KRO B;  5IMP A;  4KQU A;  3WCB A;  3SDU A;  5IK9 A;  3P5R A;  4KPD A;  5HNA A;  2Z78 A;  2J1P A;  3LOM A;  3LVS A;  1WY0 A;  5KSX F;  3WJO A;  3KRO A;  3P5P A;  1HX9 A;  5HN8 A;  4XQS F;  5H9D A;  3ACX A;  1VG3 A;  2E93 A;  4RXD A;  3CKE A;  4FP4 A;  3N0G A;  2PS5 A;  3KB9 A;  2Z50 A;  4EA1 A;  2I19 A;  2PS8 A;  3TFV A;  5A0I A;  3N49 F;  5A0J A;  5HN9 A;  3RMG A;  1UBW A;  4LFG A;  1YYQ A; 
#chains in the Genus database with same CATH topology
 1YV5 A;  1N24 A;  3DYH A;  2AET A;  4H5D F;  4RYP A;  3NRI A;  3V1X A;  3N46 F;  4QPF A;  3ICN A;  2Z4Z A;  3P8R A;  3KRF B;  3TFN A;  4JYX A;  4DEM F;  5AHU B;  5ILY A;  2H8O A;  5IVG A;  3CC9 A;  5DHI A;  4NG6 A;  3RYW A;  3LLW A;  3KRA B;  3QQV A;  3SAE A;  2FTZ A;  1VG2 A;  1FPS A;  2E8T A;  3LGZ B;  3P8L A;  4RXC A;  4LZC A;  2O1O A;  3VJ8 A;  5DJR F;  4WK5 A;  4DZW A;  4LOB A;  3VJE A;  3KRA A;  4KQS A;  3WJK A;  1N23 A;  4RXE A;  5IL3 A;  5EAT A;  5IK6 A;  1V4J A;  4MC0 A;  3PDE A;  4LUU A;  3NF2 A;  3OAB A;  1YQ7 A;  2ONG A;  4LTV A;  5ILZ A;  3WCD A;  3WJN A;  4DWB A;  1UBV A;  3ICZ A;  3ASX A;  3M01 A;  2F92 F;  1RQJ A;  2Q9Z A;  2FOR A;  4NUA A;  5B00 A;  4LLS A;  3S4J A;  3N6K F;  4KFA A;  5DHK A;  2ZCO A;  3VJA A;  2PS6 A;  3SDV A;  4KVD A;  4MC8 A;  1V4K A;  2E8U A;  3V66 A;  2F89 F;  2E8X A;  1KIZ A;  3EGT A;  5JV0 F;  4KUX A;  4H5E F;  4LFV F;  4OKZ A;  4NFJ F;  4KQ5 A;  3WCH A;  3V1V A;  1HM7 A;  2Z4V A;  4LTZ A;  3N1V F;  5ER8 A;  2Z7I A;  4L2X F;  5DJV F;  3WCE A;  3WEJ A;  3WCM A;  3PYB A;  2PS7 A;  2ZCQ A;  5AYP A;  5EAU A;  3W7F A;  5ERM A;  5ILH A;  3ZMC A;  5B0L A;  3WEG A;  5DGS F;  2PS4 A;  4P0W A;  3LSN A;  5B0M A;  4N1Z F;  5EAS A;  3WEK A;  5IKA A;  3Q1O A;  3N5H F;  4P0X A;  3TS7 A;  3WSB A;  3LEE A;  3PKO A;  3KRC B;  4LFE A;  2Z4X A;  1HM4 A;  4K10 A;  4QXS F;  4P0V A;  3WE9 A;  3VJB A;  3WCA A;  5IMI A;  3WEI A;  2E8W A;  3WSA A;  2AZJ A;  1WL2 A;  3WCF A;  1VG6 A;  1HXG A;  4JZB A;  3G4D A;  2Q80 A;  3S9V A;  3WCG A;  1UBX A;  4KVY A;  2ZEV A;  3WEF A;  3Q2Q A;  3EZ3 A;  1DGP A;  3AQ0 A;  3ZL6 A;  3ICK A;  2E94 A;  1VG7 A;  4JVJ F;  1JFA A;  3CP6 A;  5B02 A;  3Q30 A;  2F94 F;  3KRF A;  2Q58 A;  4PVY F;  3QKC A;  3VJC A;  1N20 A;  4NKE A;  4OGU A;  4E1E A;  3M0G A;  2VF6 A;  4HD1 A;  3B7L A;  1HXC A;  3ZCD A;  5I1U A;  4LPG F;  3NPR A;  3BNX A;  3SDQ A;  1JFG A;  5DW7 A;  2OPN A;  3ZMB A;  4KWD A;  5JA0 F;  3SDR A;  3RYE A;  4GAX A;  3EFQ A;  4JXN A;  3APZ A;  2Q9Y A;  3ID0 A;  4FJQ A;  3WCL A;  4LPH F;  5E8K A;  4JZX A;  2F8Z F;  1WL1 A;  2ZCR A;  3IBA A;  4LLT A;  4H5C F;  5AFX A;  3VJ9 A;  3KBK A;  4KK2 A;  2ZEU A;  5DGN F;  2AEL A;  3AE0 A;  3KRP B;  1WL3 A;  4RXA A;  4N9U A;  1YHL A;  3LDW A;  4RNQ A;  3IPI A;  3WEH A;  3ICM A;  5E8L A;  3ACW A;  3N45 F;  2RAH A;  5A0K A;  1WKZ A;  2Z7H A;  3KRP A;  3N5J F;  1HXA A;  3DYG A;  2E4O A;  5B0J A;  2ZCS A;  4LXW A;  3VJD A;  2P1C A;  2J1O A;  3MAV A;  3TC1 A;  5JV2 F;  1YYS A;  2F7M F;  4NKF A;  1KIY A;  5DIQ F;  1WL0 A;  3P41 A;  4MC3 A;  4OKM A;  5ERO A;  3LGK A;  2F8C F;  5B0I A;  5IM1 A;  3WCC A;  5B03 A;  5IMN A;  2E92 A;  4KVI A;  5DJP F;  2ONH A;  3OYR A;  4F6V A;  4F6X A;  1V4H A;  3ACY A;  1YYU A;  3M02 A;  3N0F A;  3LMD A;  4JXY A;  3WCI A;  4GP1 A;  3LG5 A;  2E8V A;  3OAC B;  4DI5 A;  1V4E A;  3M9U A;  4DXJ A;  1EZF A;  2J5C A;  2AEK A;  1VG4 A;  3WCJ A;  3KRC A;  1YHK A;  3ADZ A;  1DI1 A;  1N21 A;  5HN7 A;  5B0K A;  4KVW A;  2AZK A;  2E91 A;  3OAC A;  3N1W F;  4LIX A;  4Q23 A;  4LZ0 A;  5B01 A;  2OGD A;  4NFK F;  3PYA A;  3RBM A;  3N3L F;  1YYT A;  5CG5 A;  4XQR F;  4LZ3 A;  4E9U A;  5JUZ F;  2AZL A;  1YYR A;  5IN8 A;  5IL8 A;  5CG6 A;  1YHM A;  2E95 A;  5DGM F;  1RTR A;  4LA6 A;  3UCA A;  4OMG A;  5DZ2 A;  2OA6 A;  4EA2 A;  5IK0 A;  4KPJ A;  3PH7 A;  5ILD A;  2EWG A;  3ZOU A;  1WMW A;  4GP2 A;  1PS1 A;  1V4I A;  5ERN A;  4OMH A;  2F9K F;  5E8H A;  1N1B A;  3N3D A;  4F62 A;  2Z4Y A;  4XQT F;  1N22 A;  3WC9 A;  3OAB B;  4LA5 A;  4PVX F;  3AQC B;  3LZ9 A;  5IKH A;  2DH4 A;  2Z4W A;  4KKM A;  1ZW5 A;  3BNY A;  4EA0 A;  2QIS A;  3G4F A;  3LK5 A;  4UMJ A;  2ZY1 A;  5ILI A;  5JV1 F;  1N1Z A;  3DYF A;  4ZQ8 A;  3Q2Z A;  3SDT A;  5ILK A;  3M00 A;  5AEL A;  3LJI A;  4DHD A;  1UBY A;  2Z52 A;  4E9Z A;  2E90 A;  2OPM A;  3NPK A;  3TFP A;  3AQB B;  4DWG A;  4NFI F;  3MZV A;  4GA3 A;  1YJ4 A;  5ILJ A;  5C05 A;  1RQI A;  3KRO B;  5IMP A;  4KQU A;  3WCB A;  3SDU A;  5IK9 A;  3P5R A;  4KPD A;  5HNA A;  2Z78 A;  2J1P A;  3LOM A;  3LVS A;  1WY0 A;  5KSX F;  3WJO A;  3KRO A;  3P5P A;  1HX9 A;  5HN8 A;  4XQS F;  5H9D A;  3ACX A;  1VG3 A;  2E93 A;  4RXD A;  3CKE A;  4FP4 A;  3N0G A;  2PS5 A;  3KB9 A;  2Z50 A;  4EA1 A;  2I19 A;  2PS8 A;  3TFV A;  5A0I A;  3N49 F;  5A0J A;  5HN9 A;  3RMG A;  1UBW A;  4LFG A;  1YYQ A; 
#chains in the Genus database with same CATH homology
 1YV5 A;  1N24 A;  3DYH A;  2AET A;  4H5D F;  4RYP A;  3NRI A;  3V1X A;  3N46 F;  4QPF A;  3ICN A;  2Z4Z A;  3P8R A;  3KRF B;  3TFN A;  4JYX A;  4DEM F;  5AHU B;  5ILY A;  2H8O A;  5IVG A;  3CC9 A;  5DHI A;  4NG6 A;  3RYW A;  3LLW A;  3KRA B;  3QQV A;  3SAE A;  2FTZ A;  1VG2 A;  1FPS A;  2E8T A;  3LGZ B;  3P8L A;  4RXC A;  4LZC A;  2O1O A;  3VJ8 A;  5DJR F;  4WK5 A;  4DZW A;  4LOB A;  3VJE A;  3KRA A;  4KQS A;  3WJK A;  1N23 A;  4RXE A;  5IL3 A;  5EAT A;  5IK6 A;  1V4J A;  4MC0 A;  3PDE A;  4LUU A;  3NF2 A;  3OAB A;  1YQ7 A;  2ONG A;  4LTV A;  5ILZ A;  3WCD A;  3WJN A;  4DWB A;  1UBV A;  3ICZ A;  3ASX A;  3M01 A;  2F92 F;  1RQJ A;  2Q9Z A;  2FOR A;  4NUA A;  5B00 A;  4LLS A;  3S4J A;  3N6K F;  4KFA A;  5DHK A;  2ZCO A;  3VJA A;  2PS6 A;  3SDV A;  4KVD A;  4MC8 A;  1V4K A;  2E8U A;  3V66 A;  2F89 F;  2E8X A;  1KIZ A;  3EGT A;  5JV0 F;  4KUX A;  4H5E F;  4LFV F;  4OKZ A;  4NFJ F;  4KQ5 A;  3WCH A;  3V1V A;  1HM7 A;  2Z4V A;  4LTZ A;  3N1V F;  5ER8 A;  2Z7I A;  4L2X F;  5DJV F;  3WCE A;  3WEJ A;  3WCM A;  3PYB A;  2PS7 A;  2ZCQ A;  5AYP A;  5EAU A;  3W7F A;  5ERM A;  5ILH A;  3ZMC A;  5B0L A;  3WEG A;  5DGS F;  2PS4 A;  4P0W A;  3LSN A;  5B0M A;  4N1Z F;  5EAS A;  3WEK A;  5IKA A;  3Q1O A;  3N5H F;  4P0X A;  3TS7 A;  3WSB A;  3LEE A;  3PKO A;  3KRC B;  4LFE A;  2Z4X A;  1HM4 A;  4K10 A;  4QXS F;  4P0V A;  3WE9 A;  3VJB A;  3WCA A;  5IMI A;  3WEI A;  2E8W A;  3WSA A;  2AZJ A;  1WL2 A;  3WCF A;  1VG6 A;  1HXG A;  4JZB A;  3G4D A;  2Q80 A;  3S9V A;  3WCG A;  1UBX A;  4KVY A;  2ZEV A;  3WEF A;  3Q2Q A;  3EZ3 A;  1DGP A;  3AQ0 A;  3ZL6 A;  3ICK A;  2E94 A;  1VG7 A;  4JVJ F;  1JFA A;  3CP6 A;  5B02 A;  3Q30 A;  2F94 F;  3KRF A;  2Q58 A;  4PVY F;  3QKC A;  3VJC A;  1N20 A;  4NKE A;  4OGU A;  4E1E A;  3M0G A;  2VF6 A;  4HD1 A;  3B7L A;  1HXC A;  3ZCD A;  5I1U A;  4LPG F;  3NPR A;  3BNX A;  3SDQ A;  1JFG A;  5DW7 A;  2OPN A;  3ZMB A;  4KWD A;  5JA0 F;  3SDR A;  3RYE A;  4GAX A;  3EFQ A;  4JXN A;  3APZ A;  2Q9Y A;  3ID0 A;  4FJQ A;  3WCL A;  4LPH F;  5E8K A;  4JZX A;  2F8Z F;  1WL1 A;  2ZCR A;  3IBA A;  4LLT A;  4H5C F;  5AFX A;  3VJ9 A;  3KBK A;  4KK2 A;  2ZEU A;  5DGN F;  2AEL A;  3AE0 A;  3KRP B;  1WL3 A;  4RXA A;  4N9U A;  1YHL A;  3LDW A;  4RNQ A;  3IPI A;  3WEH A;  3ICM A;  5E8L A;  3ACW A;  3N45 F;  2RAH A;  5A0K A;  1WKZ A;  2Z7H A;  3KRP A;  3N5J F;  1HXA A;  3DYG A;  2E4O A;  5B0J A;  2ZCS A;  4LXW A;  3VJD A;  2P1C A;  2J1O A;  3MAV A;  3TC1 A;  5JV2 F;  1YYS A;  2F7M F;  4NKF A;  1KIY A;  5DIQ F;  1WL0 A;  3P41 A;  4MC3 A;  4OKM A;  5ERO A;  3LGK A;  2F8C F;  5B0I A;  5IM1 A;  3WCC A;  5B03 A;  5IMN A;  2E92 A;  4KVI A;  5DJP F;  2ONH A;  3OYR A;  4F6V A;  4F6X A;  1V4H A;  3ACY A;  1YYU A;  3M02 A;  3N0F A;  3LMD A;  4JXY A;  3WCI A;  4GP1 A;  3LG5 A;  2E8V A;  3OAC B;  4DI5 A;  1V4E A;  3M9U A;  4DXJ A;  1EZF A;  2J5C A;  2AEK A;  1VG4 A;  3WCJ A;  3KRC A;  1YHK A;  3ADZ A;  1DI1 A;  1N21 A;  5HN7 A;  5B0K A;  4KVW A;  2AZK A;  2E91 A;  3OAC A;  3N1W F;  4LIX A;  4Q23 A;  4LZ0 A;  5B01 A;  2OGD A;  4NFK F;  3PYA A;  3RBM A;  3N3L F;  1YYT A;  5CG5 A;  4XQR F;  4LZ3 A;  4E9U A;  5JUZ F;  2AZL A;  1YYR A;  5IN8 A;  5IL8 A;  5CG6 A;  1YHM A;  2E95 A;  5DGM F;  1RTR A;  4LA6 A;  3UCA A;  4OMG A;  5DZ2 A;  2OA6 A;  4EA2 A;  5IK0 A;  4KPJ A;  3PH7 A;  5ILD A;  2EWG A;  3ZOU A;  1WMW A;  4GP2 A;  1PS1 A;  1V4I A;  5ERN A;  4OMH A;  2F9K F;  5E8H A;  1N1B A;  3N3D A;  4F62 A;  2Z4Y A;  4XQT F;  1N22 A;  3WC9 A;  3OAB B;  4LA5 A;  4PVX F;  3AQC B;  3LZ9 A;  5IKH A;  2DH4 A;  2Z4W A;  4KKM A;  1ZW5 A;  3BNY A;  4EA0 A;  2QIS A;  3G4F A;  3LK5 A;  4UMJ A;  2ZY1 A;  5ILI A;  5JV1 F;  1N1Z A;  3DYF A;  4ZQ8 A;  3Q2Z A;  3SDT A;  5ILK A;  3M00 A;  5AEL A;  3LJI A;  4DHD A;  1UBY A;  2Z52 A;  4E9Z A;  2E90 A;  2OPM A;  3NPK A;  3TFP A;  3AQB B;  4DWG A;  4NFI F;  3MZV A;  4GA3 A;  1YJ4 A;  5ILJ A;  5C05 A;  1RQI A;  3KRO B;  5IMP A;  4KQU A;  3WCB A;  3SDU A;  5IK9 A;  3P5R A;  4KPD A;  5HNA A;  2Z78 A;  2J1P A;  3LOM A;  3LVS A;  1WY0 A;  5KSX F;  3WJO A;  3KRO A;  3P5P A;  1HX9 A;  5HN8 A;  4XQS F;  5H9D A;  3ACX A;  1VG3 A;  2E93 A;  4RXD A;  3CKE A;  4FP4 A;  3N0G A;  2PS5 A;  3KB9 A;  2Z50 A;  4EA1 A;  2I19 A;  2PS8 A;  3TFV A;  5A0I A;  3N49 F;  5A0J A;  5HN9 A;  3RMG A;  1UBW A;  4LFG A;  1YYQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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