2F9KF

Crystal structure of human fpps in complex with zoledronate and zn2+
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Farnesyl Diphosphate Synthase
publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 137
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f9kF00
5IMPA 2QISA 3N6KF 5IM1A 1N22A 1KIYA 3ICZA 3VJCA 3CC9A 3SAEA 1V4IA 5I1UA 2Z4XA 3LJIA 1YHMA 2P1CA 3WCHA 1FPSA 3EZ3A 2FTZA 3S4JA 1WL0A 3N3DA 3PH7A 2E8WA 2Q58A 1DGPA 1UBYA 3P5RA 5E8LA 3EFQA 3WEKA 2E95A 3QQVA 5B0IA 2ONGA 5JV2F 3CKEA 2E93A 5IL3A 2Z4VA 1N24A 1KIZA 1RQIA 3N45F 4KQUA 4DHDA 2OPMA 3N0FA 1HXGA 1V4KA 2E8XA 4NUAA 5DJVF 3RYWA 3V1XA 2ZCQA 5IVGA 3SDRA 3IPIA 5CG5A 4E9UA 5EASA 5A0IA 4NFIF 1RTRA 3KROA 4QPFA 3TFPA 4P0XA 3DYGA 3ZCDA 3M01A 4OKMA 5AYPA 5ERNA 1DI1A 4GP1A 3M00A 4H5CF 3LMDA 3KRFB 2E8TA 1HXAA 4XQSF 4JZXA 5ILYA 3ICKA 3VJDA 4KWDA 3WEGA 3WCLA 2Z52A 1WMWA 4JZBA 4LFGA 4RXAA 4DZWA 4JXNA 3WJOA 1V4EA 3LOMA 2OPNA 3WEFA 2E8VA 2PS8A 5DGMF 2Z50A 2PS4A 1V4JA 2F8ZF 3AQBB 3LZ9A 4LIXA 3AQCB 1WKZA 2F7MF 4E1EA 4GA3A 3PYAA 2E4OA 5B0KA 3RYEA 1JFAA 3OYRA 3Q2ZA 3WC9A 3V66A 5AHUB 2PS7A 5B03A 3BNXA 2PS6A 4KFAA 3ID0A 3TC1A 3BNYA 3KRAA 5C05A 5ILIA 3TFVA 3ACWA 5JUZF 4XQRF 4JVJF 4KVDA 3LDWA 3ACYA 4GP2A 1HXCA 3DYFA 3P41A 3VJ9A 4OKZA 5JV0F 3ZL6A 4KPDA 4RXEA 3SDUA 5IL8A 2Z4ZA 1N23A 4NFJF 2Q80A 2AELA 1YYRA 3WJKA 1PS1A 4QXSF 3TS7A 3KRPA 3N46F 3WCFA 4JXYA 1EZFA 5KSXF 5ILJA 4NFKF 4L2XF 1V4HA 4LA5A 4OGUA 5IKAA 2I19A 3W7FA 3OABB 3PYBA 5AELA 5A0JA 5E8HA 5AFXA 2J5CA 2RAHA 2ONHA 2E8UA 3VJAA 1YJ4A 3AQ0A 3B7LA 3APZA 3KBKA 2AZLA 2ZEUA 3WCCA 3AE0A 4EA2A 5IN8A 3LVSA 4KQSA 1VG2A 4DWGA 5IK6A 3KRCB 3WCGA 3M02A 1WY0A 2J1PA 3S9VA 3NF2A 4LUUA 4MC8A 1WL3A 4UMJA 3WEJA 3WCBA 2OA6A 4NKFA 1HM4A 3WJNA 3WSAA 4LTVA 3NRIA 3N1WF 4EA1A 3OACA 3WCEA 4H5EF 4JYXA 4DEMF 3N49F 2Z7HA 4KKMA 4LTZA 2FORA 5IMIA 5IMNA 3DYHA 5DJRF 3P5PA 1HX9A 3VJBA 4H5DF 4KQ5A 2F94F 3LG5A 1UBXA 5ILKA 3TFNA 3Q30A 1YQ7A 4F6XA 4LZ3A 4F62A 5B00A 3SDVA 4F6VA 3EGTA 5CG6A 3QKCA 2F89F 3IBAA 5DJPF 2E90A 2O1OA 1YYTA 3ACXA 3WE9A 5ILHA 3N1VF 4DI5A 3P8LA 3ICMA 2ZCSA 3ASXA 2VF6A 5DHIA 5IK9A 2J1OA 3V1VA 4EA0A 1UBWA 2E91A 1UBVA 1ZW5A 1N1BA 4K10A 3PKOA 5JA0F 4PVYF 3LLWA 3NPKA 3Q2QA 4DWBA 2Z4YA 5ERMA 2Z7IA 5DZ2A 3UCAA 2OGDA 3Q1OA 2Z4WA 2AZKA 2DH4A 1N1ZA 3ADZA 3VJ8A 4GAXA 1RQJA 1VG4A 1YYQA 3RBMA 3ZMCA 4DXJA 3SDTA 1HM7A 2AETA 2EWGA 3ZMBA 5HN8A 4KK2A 3KROB 3LSNA 5EATA 5E8KA 5B0MA 5HN7A 3CP6A 3WCAA 4NKEA 3M9UA 1WL1A 5IKHA 5H9DA 3PDEA 3WCMA 4P0VA 5A0KA 4MC3A 5DIQF 3G4DA 4P0WA 3MAVA 3LEEA 2AEKA 5B0JA 2PS5A 4LZ0A 4LA6A 4KVYA 3WSBA 3ZOUA 4LZCA 4RNQA 5B02A 4LFVF 2Q9YA 3OACB 4FP4A 4LLTA 3WCJA 4KUXA 3LGZB 1YYSA 4OMGA 5B0LA 1YYUA 3ICNA 3SDQA 3LK5A 2ZEVA 3KB9A 4HD1A 2Q9ZA 3N3LF 3N5HF 4NG6A 2Z78A 4KVWA 3OABA 1WL2A 3RMGA 3N0GA 5IK0A 5ER8A 3KRAB 5DW7A 4LXWA 4RXDA 5B01A 1JFGA 2H8OA 4MC0A 3LGKA 1VG7A 1VG3A 4N1ZF 1YV5A 4LPHF 3WCDA 4XQTF 2ZCRA 5ILZA 3P8RA 5EROA 2F92F 4KVIA 2ZCOA 4E9ZA 4PVXF 1YHLA 5DGNF 4LPGF 2E94A 4LOBA 3KRPB 5DHKA 3VJEA 3KRCA 4RYPA 3KRFA 4Q23A 4OMHA 4RXCA 3WCIA 4WK5A 2F8CF 4ZQ8A 1N21A 5HN9A 5DGSF 5EAUA 3M0GA 4LLSA 3MZVA 3NPRA 1VG6A 4N9UA 3N5JF 2E92A 2ZY1A 1YHKA 4LFEA 4FJQA 2F9KF 2AZJA 5JV1F 4KPJA 1N20A 5HNAA 5ILDA 3WEHA 3WEIA 3G4FA
chains in the Genus database with same CATH superfamily
5IMPA 2QISA 3N6KF 5IM1A 1N22A 1KIYA 3ICZA 3VJCA 3CC9A 3SAEA 1V4IA 5I1UA 2Z4XA 3LJIA 1YHMA 2P1CA 3WCHA 1FPSA 3EZ3A 2FTZA 3S4JA 1WL0A 3N3DA 3PH7A 2E8WA 2Q58A 1DGPA 1UBYA 3P5RA 5E8LA 3EFQA 3WEKA 2E95A 3QQVA 5B0IA 2ONGA 5JV2F 3CKEA 2E93A 5IL3A 2Z4VA 1N24A 1KIZA 1RQIA 3N45F 4KQUA 4DHDA 2OPMA 3N0FA 1HXGA 1V4KA 2E8XA 4NUAA 5DJVF 3RYWA 3V1XA 2ZCQA 5IVGA 3SDRA 3IPIA 5CG5A 4E9UA 5EASA 5A0IA 4NFIF 1RTRA 3KROA 4QPFA 3TFPA 4P0XA 3DYGA 3ZCDA 3M01A 4OKMA 5AYPA 5ERNA 1DI1A 4GP1A 3M00A 4H5CF 3LMDA 3KRFB 2E8TA 1HXAA 4XQSF 4JZXA 5ILYA 3ICKA 3VJDA 4KWDA 3WEGA 3WCLA 2Z52A 1WMWA 4JZBA 4LFGA 4RXAA 4DZWA 4JXNA 3WJOA 1V4EA 3LOMA 2OPNA 3WEFA 2E8VA 2PS8A 5DGMF 2Z50A 2PS4A 1V4JA 2F8ZF 3AQBB 3LZ9A 4LIXA 3AQCB 1WKZA 2F7MF 4E1EA 4GA3A 3PYAA 2E4OA 5B0KA 3RYEA 1JFAA 3OYRA 3Q2ZA 3WC9A 3V66A 5AHUB 2PS7A 5B03A 3BNXA 2PS6A 4KFAA 3ID0A 3TC1A 3BNYA 3KRAA 5C05A 5ILIA 3TFVA 3ACWA 5JUZF 4XQRF 4JVJF 4KVDA 3LDWA 3ACYA 4GP2A 1HXCA 3DYFA 3P41A 3VJ9A 4OKZA 5JV0F 3ZL6A 4KPDA 4RXEA 3SDUA 5IL8A 2Z4ZA 1N23A 4NFJF 2Q80A 2AELA 1YYRA 3WJKA 1PS1A 4QXSF 3TS7A 3KRPA 3N46F 3WCFA 4JXYA 1EZFA 5KSXF 5ILJA 4NFKF 4L2XF 1V4HA 4LA5A 4OGUA 5IKAA 2I19A 3W7FA 3OABB 3PYBA 5AELA 5A0JA 5E8HA 5AFXA 2J5CA 2RAHA 2ONHA 2E8UA 3VJAA 1YJ4A 3AQ0A 3B7LA 3APZA 3KBKA 2AZLA 2ZEUA 3WCCA 3AE0A 4EA2A 5IN8A 3LVSA 4KQSA 1VG2A 4DWGA 5IK6A 3KRCB 3WCGA 3M02A 1WY0A 2J1PA 3S9VA 3NF2A 4LUUA 4MC8A 1WL3A 4UMJA 3WEJA 3WCBA 2OA6A 4NKFA 1HM4A 3WJNA 3WSAA 4LTVA 3NRIA 3N1WF 4EA1A 3OACA 3WCEA 4H5EF 4JYXA 4DEMF 3N49F 2Z7HA 4KKMA 4LTZA 2FORA 5IMIA 5IMNA 3DYHA 5DJRF 3P5PA 1HX9A 3VJBA 4H5DF 4KQ5A 2F94F 3LG5A 1UBXA 5ILKA 3TFNA 3Q30A 1YQ7A 4F6XA 4LZ3A 4F62A 5B00A 3SDVA 4F6VA 3EGTA 5CG6A 3QKCA 2F89F 3IBAA 5DJPF 2E90A 2O1OA 1YYTA 3ACXA 3WE9A 5ILHA 3N1VF 4DI5A 3P8LA 3ICMA 2ZCSA 3ASXA 2VF6A 5DHIA 5IK9A 2J1OA 3V1VA 4EA0A 1UBWA 2E91A 1UBVA 1ZW5A 1N1BA 4K10A 3PKOA 5JA0F 4PVYF 3LLWA 3NPKA 3Q2QA 4DWBA 2Z4YA 5ERMA 2Z7IA 5DZ2A 3UCAA 2OGDA 3Q1OA 2Z4WA 2AZKA 2DH4A 1N1ZA 3ADZA 3VJ8A 4GAXA 1RQJA 1VG4A 1YYQA 3RBMA 3ZMCA 4DXJA 3SDTA 1HM7A 2AETA 2EWGA 3ZMBA 5HN8A 4KK2A 3KROB 3LSNA 5EATA 5E8KA 5B0MA 5HN7A 3CP6A 3WCAA 4NKEA 3M9UA 1WL1A 5IKHA 5H9DA 3PDEA 3WCMA 4P0VA 5A0KA 4MC3A 5DIQF 3G4DA 4P0WA 3MAVA 3LEEA 2AEKA 5B0JA 2PS5A 4LZ0A 4LA6A 4KVYA 3WSBA 3ZOUA 4LZCA 4RNQA 5B02A 4LFVF 2Q9YA 3OACB 4FP4A 4LLTA 3WCJA 4KUXA 3LGZB 1YYSA 4OMGA 5B0LA 1YYUA 3ICNA 3SDQA 3LK5A 2ZEVA 3KB9A 4HD1A 2Q9ZA 3N3LF 3N5HF 4NG6A 2Z78A 4KVWA 3OABA 1WL2A 3RMGA 3N0GA 5IK0A 5ER8A 3KRAB 5DW7A 4LXWA 4RXDA 5B01A 1JFGA 2H8OA 4MC0A 3LGKA 1VG7A 1VG3A 4N1ZF 1YV5A 4LPHF 3WCDA 4XQTF 2ZCRA 5ILZA 3P8RA 5EROA 2F92F 4KVIA 2ZCOA 4E9ZA 4PVXF 1YHLA 5DGNF 4LPGF 2E94A 4LOBA 3KRPB 5DHKA 3VJEA 3KRCA 4RYPA 3KRFA 4Q23A 4OMHA 4RXCA 3WCIA 4WK5A 2F8CF 4ZQ8A 1N21A 5HN9A 5DGSF 5EAUA 3M0GA 4LLSA 3MZVA 3NPRA 1VG6A 4N9UA 3N5JF 2E92A 2ZY1A 1YHKA 4LFEA 4FJQA 2F9KF 2AZJA 5JV1F 4KPJA 1N20A 5HNAA 5ILDA 3WEHA 3WEIA 3G4FA
chains in the Genus database with same CATH topology
5IMPA 2QISA 3N6KF 5IM1A 1N22A 1KIYA 3ICZA 3VJCA 3CC9A 3SAEA 1V4IA 5I1UA 2Z4XA 3LJIA 1YHMA 2P1CA 3WCHA 1FPSA 3EZ3A 2FTZA 3S4JA 1WL0A 3N3DA 3PH7A 2E8WA 2Q58A 1DGPA 1UBYA 3P5RA 5E8LA 3EFQA 3WEKA 2E95A 3QQVA 5B0IA 2ONGA 5JV2F 3CKEA 2E93A 5IL3A 2Z4VA 1N24A 1KIZA 1RQIA 3N45F 4KQUA 4DHDA 2OPMA 3N0FA 1HXGA 1V4KA 2E8XA 4NUAA 5DJVF 3RYWA 3V1XA 2ZCQA 5IVGA 3SDRA 3IPIA 5CG5A 4E9UA 5EASA 5A0IA 4NFIF 1RTRA 3KROA 4QPFA 3TFPA 4P0XA 3DYGA 3ZCDA 3M01A 4OKMA 5AYPA 5ERNA 1DI1A 4GP1A 3M00A 4H5CF 3LMDA 3KRFB 2E8TA 1HXAA 4XQSF 4JZXA 5ILYA 3ICKA 3VJDA 4KWDA 3WEGA 3WCLA 2Z52A 1WMWA 4JZBA 4LFGA 4RXAA 4DZWA 4JXNA 3WJOA 1V4EA 3LOMA 2OPNA 3WEFA 2E8VA 2PS8A 5DGMF 2Z50A 2PS4A 1V4JA 2F8ZF 3AQBB 3LZ9A 4LIXA 3AQCB 1WKZA 2F7MF 4E1EA 4GA3A 3PYAA 2E4OA 5B0KA 3RYEA 1JFAA 3OYRA 3Q2ZA 3WC9A 3V66A 5AHUB 2PS7A 5B03A 3BNXA 2PS6A 4KFAA 3ID0A 3TC1A 3BNYA 3KRAA 5C05A 5ILIA 3TFVA 3ACWA 5JUZF 4XQRF 4JVJF 4KVDA 3LDWA 3ACYA 4GP2A 1HXCA 3DYFA 3P41A 3VJ9A 4OKZA 5JV0F 3ZL6A 4KPDA 4RXEA 3SDUA 5IL8A 2Z4ZA 1N23A 4NFJF 2Q80A 2AELA 1YYRA 3WJKA 1PS1A 4QXSF 3TS7A 3KRPA 3N46F 3WCFA 4JXYA 1EZFA 5KSXF 5ILJA 4NFKF 4L2XF 1V4HA 4LA5A 4OGUA 5IKAA 2I19A 3W7FA 3OABB 3PYBA 5AELA 5A0JA 5E8HA 5AFXA 2J5CA 2RAHA 2ONHA 2E8UA 3VJAA 1YJ4A 3AQ0A 3B7LA 3APZA 3KBKA 2AZLA 2ZEUA 3WCCA 3AE0A 4EA2A 5IN8A 3LVSA 4KQSA 1VG2A 4DWGA 5IK6A 3KRCB 3WCGA 3M02A 1WY0A 2J1PA 3S9VA 3NF2A 4LUUA 4MC8A 1WL3A 4UMJA 3WEJA 3WCBA 2OA6A 4NKFA 1HM4A 3WJNA 3WSAA 4LTVA 3NRIA 3N1WF 4EA1A 3OACA 3WCEA 4H5EF 4JYXA 4DEMF 3N49F 2Z7HA 4KKMA 4LTZA 2FORA 5IMIA 5IMNA 3DYHA 5DJRF 3P5PA 1HX9A 3VJBA 4H5DF 4KQ5A 2F94F 3LG5A 1UBXA 5ILKA 3TFNA 3Q30A 1YQ7A 4F6XA 4LZ3A 4F62A 5B00A 3SDVA 4F6VA 3EGTA 5CG6A 3QKCA 2F89F 3IBAA 5DJPF 2E90A 2O1OA 1YYTA 3ACXA 3WE9A 5ILHA 3N1VF 4DI5A 3P8LA 3ICMA 2ZCSA 3ASXA 2VF6A 5DHIA 5IK9A 2J1OA 3V1VA 4EA0A 1UBWA 2E91A 1UBVA 1ZW5A 1N1BA 4K10A 3PKOA 5JA0F 4PVYF 3LLWA 3NPKA 3Q2QA 4DWBA 2Z4YA 5ERMA 2Z7IA 5DZ2A 3UCAA 2OGDA 3Q1OA 2Z4WA 2AZKA 2DH4A 1N1ZA 3ADZA 3VJ8A 4GAXA 1RQJA 1VG4A 1YYQA 3RBMA 3ZMCA 4DXJA 3SDTA 1HM7A 2AETA 2EWGA 3ZMBA 5HN8A 4KK2A 3KROB 3LSNA 5EATA 5E8KA 5B0MA 5HN7A 3CP6A 3WCAA 4NKEA 3M9UA 1WL1A 5IKHA 5H9DA 3PDEA 3WCMA 4P0VA 5A0KA 4MC3A 5DIQF 3G4DA 4P0WA 3MAVA 3LEEA 2AEKA 5B0JA 2PS5A 4LZ0A 4LA6A 4KVYA 3WSBA 3ZOUA 4LZCA 4RNQA 5B02A 4LFVF 2Q9YA 3OACB 4FP4A 4LLTA 3WCJA 4KUXA 3LGZB 1YYSA 4OMGA 5B0LA 1YYUA 3ICNA 3SDQA 3LK5A 2ZEVA 3KB9A 4HD1A 2Q9ZA 3N3LF 3N5HF 4NG6A 2Z78A 4KVWA 3OABA 1WL2A 3RMGA 3N0GA 5IK0A 5ER8A 3KRAB 5DW7A 4LXWA 4RXDA 5B01A 1JFGA 2H8OA 4MC0A 3LGKA 1VG7A 1VG3A 4N1ZF 1YV5A 4LPHF 3WCDA 4XQTF 2ZCRA 5ILZA 3P8RA 5EROA 2F92F 4KVIA 2ZCOA 4E9ZA 4PVXF 1YHLA 5DGNF 4LPGF 2E94A 4LOBA 3KRPB 5DHKA 3VJEA 3KRCA 4RYPA 3KRFA 4Q23A 4OMHA 4RXCA 3WCIA 4WK5A 2F8CF 4ZQ8A 1N21A 5HN9A 5DGSF 5EAUA 3M0GA 4LLSA 3MZVA 3NPRA 1VG6A 4N9UA 3N5JF 2E92A 2ZY1A 1YHKA 4LFEA 4FJQA 2F9KF 2AZJA 5JV1F 4KPJA 1N20A 5HNAA 5ILDA 3WEHA 3WEIA 3G4FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IMP A;  2QIS A;  3N6K F;  5IM1 A;  1N22 A;  1KIY A;  3ICZ A;  3VJC A;  3CC9 A;  3SAE A;  1V4I A;  5I1U A;  2Z4X A;  3LJI A;  1YHM A;  2P1C A;  3WCH A;  1FPS A;  3EZ3 A;  2FTZ A;  3S4J A;  1WL0 A;  3N3D A;  3PH7 A;  2E8W A;  2Q58 A;  1DGP A;  1UBY A;  3P5R A;  5E8L A;  3EFQ A;  3WEK A;  2E95 A;  3QQV A;  5B0I A;  2ONG A;  5JV2 F;  3CKE A;  2E93 A;  5IL3 A;  2Z4V A;  1N24 A;  1KIZ A;  1RQI A;  3N45 F;  4KQU A;  4DHD A;  2OPM A;  3N0F A;  1HXG A;  1V4K A;  2E8X A;  4NUA A;  5DJV F;  3RYW A;  3V1X A;  2ZCQ A;  5IVG A;  3SDR A;  3IPI A;  5CG5 A;  4E9U A;  5EAS A;  5A0I A;  4NFI F;  1RTR A;  3KRO A;  4QPF A;  3TFP A;  4P0X A;  3DYG A;  3ZCD A;  3M01 A;  4OKM A;  5AYP A;  5ERN A;  1DI1 A;  4GP1 A;  3M00 A;  4H5C F;  3LMD A;  3KRF B;  2E8T A;  1HXA A;  4XQS F;  4JZX A;  5ILY A;  3ICK A;  3VJD A;  4KWD A;  3WEG A;  3WCL A;  2Z52 A;  1WMW A;  4JZB A;  4LFG A;  4RXA A;  4DZW A;  4JXN A;  3WJO A;  1V4E A;  3LOM A;  2OPN A;  3WEF A;  2E8V A;  2PS8 A;  5DGM F;  2Z50 A;  2PS4 A;  1V4J A;  2F8Z F;  3AQB B;  3LZ9 A;  4LIX A;  3AQC B;  1WKZ A;  2F7M F;  4E1E A;  4GA3 A;  3PYA A;  2E4O A;  5B0K A;  3RYE A;  1JFA A;  3OYR A;  3Q2Z A;  3WC9 A;  3V66 A;  5AHU B;  2PS7 A;  5B03 A;  3BNX A;  2PS6 A;  4KFA A;  3ID0 A;  3TC1 A;  3BNY A;  3KRA A;  5C05 A;  5ILI A;  3TFV A;  3ACW A;  5JUZ F;  4XQR F;  4JVJ F;  4KVD A;  3LDW A;  3ACY A;  4GP2 A;  1HXC A;  3DYF A;  3P41 A;  3VJ9 A;  4OKZ A;  5JV0 F;  3ZL6 A;  4KPD A;  4RXE A;  3SDU A;  5IL8 A;  2Z4Z A;  1N23 A;  4NFJ F;  2Q80 A;  2AEL A;  1YYR A;  3WJK A;  1PS1 A;  4QXS F;  3TS7 A;  3KRP A;  3N46 F;  3WCF A;  4JXY A;  1EZF A;  5KSX F;  5ILJ A;  4NFK F;  4L2X F;  1V4H A;  4LA5 A;  4OGU A;  5IKA A;  2I19 A;  3W7F A;  3OAB B;  3PYB A;  5AEL A;  5A0J A;  5E8H A;  5AFX A;  2J5C A;  2RAH A;  2ONH A;  2E8U A;  3VJA A;  1YJ4 A;  3AQ0 A;  3B7L A;  3APZ A;  3KBK A;  2AZL A;  2ZEU A;  3WCC A;  3AE0 A;  4EA2 A;  5IN8 A;  3LVS A;  4KQS A;  1VG2 A;  4DWG A;  5IK6 A;  3KRC B;  3WCG A;  3M02 A;  1WY0 A;  2J1P A;  3S9V A;  3NF2 A;  4LUU A;  4MC8 A;  1WL3 A;  4UMJ A;  3WEJ A;  3WCB A;  2OA6 A;  4NKF A;  1HM4 A;  3WJN A;  3WSA A;  4LTV A;  3NRI A;  3N1W F;  4EA1 A;  3OAC A;  3WCE A;  4H5E F;  4JYX A;  4DEM F;  3N49 F;  2Z7H A;  4KKM A;  4LTZ A;  2FOR A;  5IMI A;  5IMN A;  3DYH A;  5DJR F;  3P5P A;  1HX9 A;  3VJB A;  4H5D F;  4KQ5 A;  2F94 F;  3LG5 A;  1UBX A;  5ILK A;  3TFN A;  3Q30 A;  1YQ7 A;  4F6X A;  4LZ3 A;  4F62 A;  5B00 A;  3SDV A;  4F6V A;  3EGT A;  5CG6 A;  3QKC A;  2F89 F;  3IBA A;  5DJP F;  2E90 A;  2O1O A;  1YYT A;  3ACX A;  3WE9 A;  5ILH A;  3N1V F;  4DI5 A;  3P8L A;  3ICM A;  2ZCS A;  3ASX A;  2VF6 A;  5DHI A;  5IK9 A;  2J1O A;  3V1V A;  4EA0 A;  1UBW A;  2E91 A;  1UBV A;  1ZW5 A;  1N1B A;  4K10 A;  3PKO A;  5JA0 F;  4PVY F;  3LLW A;  3NPK A;  3Q2Q A;  4DWB A;  2Z4Y A;  5ERM A;  2Z7I A;  5DZ2 A;  3UCA A;  2OGD A;  3Q1O A;  2Z4W A;  2AZK A;  2DH4 A;  1N1Z A;  3ADZ A;  3VJ8 A;  4GAX A;  1RQJ A;  1VG4 A;  1YYQ A;  3RBM A;  3ZMC A;  4DXJ A;  3SDT A;  1HM7 A;  2AET A;  2EWG A;  3ZMB A;  5HN8 A;  4KK2 A;  3KRO B;  3LSN A;  5EAT A;  5E8K A;  5B0M A;  5HN7 A;  3CP6 A;  3WCA A;  4NKE A;  3M9U A;  1WL1 A;  5IKH A;  5H9D A;  3PDE A;  3WCM A;  4P0V A;  5A0K A;  4MC3 A;  5DIQ F;  3G4D A;  4P0W A;  3MAV A;  3LEE A;  2AEK A;  5B0J A;  2PS5 A;  4LZ0 A;  4LA6 A;  4KVY A;  3WSB A;  3ZOU A;  4LZC A;  4RNQ A;  5B02 A;  4LFV F;  2Q9Y A;  3OAC B;  4FP4 A;  4LLT A;  3WCJ A;  4KUX A;  3LGZ B;  1YYS A;  4OMG A;  5B0L A;  1YYU A;  3ICN A;  3SDQ A;  3LK5 A;  2ZEV A;  3KB9 A;  4HD1 A;  2Q9Z A;  3N3L F;  3N5H F;  4NG6 A;  2Z78 A;  4KVW A;  3OAB A;  1WL2 A;  3RMG A;  3N0G A;  5IK0 A;  5ER8 A;  3KRA B;  5DW7 A;  4LXW A;  4RXD A;  5B01 A;  1JFG A;  2H8O A;  4MC0 A;  3LGK A;  1VG7 A;  1VG3 A;  4N1Z F;  1YV5 A;  4LPH F;  3WCD A;  4XQT F;  2ZCR A;  5ILZ A;  3P8R A;  5ERO A;  2F92 F;  4KVI A;  2ZCO A;  4E9Z A;  4PVX F;  1YHL A;  5DGN F;  4LPG F;  2E94 A;  4LOB A;  3KRP B;  5DHK A;  3VJE A;  3KRC A;  4RYP A;  3KRF A;  4Q23 A;  4OMH A;  4RXC A;  3WCI A;  4WK5 A;  2F8C F;  4ZQ8 A;  1N21 A;  5HN9 A;  5DGS F;  5EAU A;  3M0G A;  4LLS A;  3MZV A;  3NPR A;  1VG6 A;  4N9U A;  3N5J F;  2E92 A;  2ZY1 A;  1YHK A;  4LFE A;  4FJQ A;  2F9K F;  2AZJ A;  5JV1 F;  4KPJ A;  1N20 A;  5HNA A;  5ILD A;  3WEH A;  3WEI A;  3G4F A; 
#chains in the Genus database with same CATH topology
 5IMP A;  2QIS A;  3N6K F;  5IM1 A;  1N22 A;  1KIY A;  3ICZ A;  3VJC A;  3CC9 A;  3SAE A;  1V4I A;  5I1U A;  2Z4X A;  3LJI A;  1YHM A;  2P1C A;  3WCH A;  1FPS A;  3EZ3 A;  2FTZ A;  3S4J A;  1WL0 A;  3N3D A;  3PH7 A;  2E8W A;  2Q58 A;  1DGP A;  1UBY A;  3P5R A;  5E8L A;  3EFQ A;  3WEK A;  2E95 A;  3QQV A;  5B0I A;  2ONG A;  5JV2 F;  3CKE A;  2E93 A;  5IL3 A;  2Z4V A;  1N24 A;  1KIZ A;  1RQI A;  3N45 F;  4KQU A;  4DHD A;  2OPM A;  3N0F A;  1HXG A;  1V4K A;  2E8X A;  4NUA A;  5DJV F;  3RYW A;  3V1X A;  2ZCQ A;  5IVG A;  3SDR A;  3IPI A;  5CG5 A;  4E9U A;  5EAS A;  5A0I A;  4NFI F;  1RTR A;  3KRO A;  4QPF A;  3TFP A;  4P0X A;  3DYG A;  3ZCD A;  3M01 A;  4OKM A;  5AYP A;  5ERN A;  1DI1 A;  4GP1 A;  3M00 A;  4H5C F;  3LMD A;  3KRF B;  2E8T A;  1HXA A;  4XQS F;  4JZX A;  5ILY A;  3ICK A;  3VJD A;  4KWD A;  3WEG A;  3WCL A;  2Z52 A;  1WMW A;  4JZB A;  4LFG A;  4RXA A;  4DZW A;  4JXN A;  3WJO A;  1V4E A;  3LOM A;  2OPN A;  3WEF A;  2E8V A;  2PS8 A;  5DGM F;  2Z50 A;  2PS4 A;  1V4J A;  2F8Z F;  3AQB B;  3LZ9 A;  4LIX A;  3AQC B;  1WKZ A;  2F7M F;  4E1E A;  4GA3 A;  3PYA A;  2E4O A;  5B0K A;  3RYE A;  1JFA A;  3OYR A;  3Q2Z A;  3WC9 A;  3V66 A;  5AHU B;  2PS7 A;  5B03 A;  3BNX A;  2PS6 A;  4KFA A;  3ID0 A;  3TC1 A;  3BNY A;  3KRA A;  5C05 A;  5ILI A;  3TFV A;  3ACW A;  5JUZ F;  4XQR F;  4JVJ F;  4KVD A;  3LDW A;  3ACY A;  4GP2 A;  1HXC A;  3DYF A;  3P41 A;  3VJ9 A;  4OKZ A;  5JV0 F;  3ZL6 A;  4KPD A;  4RXE A;  3SDU A;  5IL8 A;  2Z4Z A;  1N23 A;  4NFJ F;  2Q80 A;  2AEL A;  1YYR A;  3WJK A;  1PS1 A;  4QXS F;  3TS7 A;  3KRP A;  3N46 F;  3WCF A;  4JXY A;  1EZF A;  5KSX F;  5ILJ A;  4NFK F;  4L2X F;  1V4H A;  4LA5 A;  4OGU A;  5IKA A;  2I19 A;  3W7F A;  3OAB B;  3PYB A;  5AEL A;  5A0J A;  5E8H A;  5AFX A;  2J5C A;  2RAH A;  2ONH A;  2E8U A;  3VJA A;  1YJ4 A;  3AQ0 A;  3B7L A;  3APZ A;  3KBK A;  2AZL A;  2ZEU A;  3WCC A;  3AE0 A;  4EA2 A;  5IN8 A;  3LVS A;  4KQS A;  1VG2 A;  4DWG A;  5IK6 A;  3KRC B;  3WCG A;  3M02 A;  1WY0 A;  2J1P A;  3S9V A;  3NF2 A;  4LUU A;  4MC8 A;  1WL3 A;  4UMJ A;  3WEJ A;  3WCB A;  2OA6 A;  4NKF A;  1HM4 A;  3WJN A;  3WSA A;  4LTV A;  3NRI A;  3N1W F;  4EA1 A;  3OAC A;  3WCE A;  4H5E F;  4JYX A;  4DEM F;  3N49 F;  2Z7H A;  4KKM A;  4LTZ A;  2FOR A;  5IMI A;  5IMN A;  3DYH A;  5DJR F;  3P5P A;  1HX9 A;  3VJB A;  4H5D F;  4KQ5 A;  2F94 F;  3LG5 A;  1UBX A;  5ILK A;  3TFN A;  3Q30 A;  1YQ7 A;  4F6X A;  4LZ3 A;  4F62 A;  5B00 A;  3SDV A;  4F6V A;  3EGT A;  5CG6 A;  3QKC A;  2F89 F;  3IBA A;  5DJP F;  2E90 A;  2O1O A;  1YYT A;  3ACX A;  3WE9 A;  5ILH A;  3N1V F;  4DI5 A;  3P8L A;  3ICM A;  2ZCS A;  3ASX A;  2VF6 A;  5DHI A;  5IK9 A;  2J1O A;  3V1V A;  4EA0 A;  1UBW A;  2E91 A;  1UBV A;  1ZW5 A;  1N1B A;  4K10 A;  3PKO A;  5JA0 F;  4PVY F;  3LLW A;  3NPK A;  3Q2Q A;  4DWB A;  2Z4Y A;  5ERM A;  2Z7I A;  5DZ2 A;  3UCA A;  2OGD A;  3Q1O A;  2Z4W A;  2AZK A;  2DH4 A;  1N1Z A;  3ADZ A;  3VJ8 A;  4GAX A;  1RQJ A;  1VG4 A;  1YYQ A;  3RBM A;  3ZMC A;  4DXJ A;  3SDT A;  1HM7 A;  2AET A;  2EWG A;  3ZMB A;  5HN8 A;  4KK2 A;  3KRO B;  3LSN A;  5EAT A;  5E8K A;  5B0M A;  5HN7 A;  3CP6 A;  3WCA A;  4NKE A;  3M9U A;  1WL1 A;  5IKH A;  5H9D A;  3PDE A;  3WCM A;  4P0V A;  5A0K A;  4MC3 A;  5DIQ F;  3G4D A;  4P0W A;  3MAV A;  3LEE A;  2AEK A;  5B0J A;  2PS5 A;  4LZ0 A;  4LA6 A;  4KVY A;  3WSB A;  3ZOU A;  4LZC A;  4RNQ A;  5B02 A;  4LFV F;  2Q9Y A;  3OAC B;  4FP4 A;  4LLT A;  3WCJ A;  4KUX A;  3LGZ B;  1YYS A;  4OMG A;  5B0L A;  1YYU A;  3ICN A;  3SDQ A;  3LK5 A;  2ZEV A;  3KB9 A;  4HD1 A;  2Q9Z A;  3N3L F;  3N5H F;  4NG6 A;  2Z78 A;  4KVW A;  3OAB A;  1WL2 A;  3RMG A;  3N0G A;  5IK0 A;  5ER8 A;  3KRA B;  5DW7 A;  4LXW A;  4RXD A;  5B01 A;  1JFG A;  2H8O A;  4MC0 A;  3LGK A;  1VG7 A;  1VG3 A;  4N1Z F;  1YV5 A;  4LPH F;  3WCD A;  4XQT F;  2ZCR A;  5ILZ A;  3P8R A;  5ERO A;  2F92 F;  4KVI A;  2ZCO A;  4E9Z A;  4PVX F;  1YHL A;  5DGN F;  4LPG F;  2E94 A;  4LOB A;  3KRP B;  5DHK A;  3VJE A;  3KRC A;  4RYP A;  3KRF A;  4Q23 A;  4OMH A;  4RXC A;  3WCI A;  4WK5 A;  2F8C F;  4ZQ8 A;  1N21 A;  5HN9 A;  5DGS F;  5EAU A;  3M0G A;  4LLS A;  3MZV A;  3NPR A;  1VG6 A;  4N9U A;  3N5J F;  2E92 A;  2ZY1 A;  1YHK A;  4LFE A;  4FJQ A;  2F9K F;  2AZJ A;  5JV1 F;  4KPJ A;  1N20 A;  5HNA A;  5ILD A;  3WEH A;  3WEI A;  3G4F A; 
#chains in the Genus database with same CATH homology
 5IMP A;  2QIS A;  3N6K F;  5IM1 A;  1N22 A;  1KIY A;  3ICZ A;  3VJC A;  3CC9 A;  3SAE A;  1V4I A;  5I1U A;  2Z4X A;  3LJI A;  1YHM A;  2P1C A;  3WCH A;  1FPS A;  3EZ3 A;  2FTZ A;  3S4J A;  1WL0 A;  3N3D A;  3PH7 A;  2E8W A;  2Q58 A;  1DGP A;  1UBY A;  3P5R A;  5E8L A;  3EFQ A;  3WEK A;  2E95 A;  3QQV A;  5B0I A;  2ONG A;  5JV2 F;  3CKE A;  2E93 A;  5IL3 A;  2Z4V A;  1N24 A;  1KIZ A;  1RQI A;  3N45 F;  4KQU A;  4DHD A;  2OPM A;  3N0F A;  1HXG A;  1V4K A;  2E8X A;  4NUA A;  5DJV F;  3RYW A;  3V1X A;  2ZCQ A;  5IVG A;  3SDR A;  3IPI A;  5CG5 A;  4E9U A;  5EAS A;  5A0I A;  4NFI F;  1RTR A;  3KRO A;  4QPF A;  3TFP A;  4P0X A;  3DYG A;  3ZCD A;  3M01 A;  4OKM A;  5AYP A;  5ERN A;  1DI1 A;  4GP1 A;  3M00 A;  4H5C F;  3LMD A;  3KRF B;  2E8T A;  1HXA A;  4XQS F;  4JZX A;  5ILY A;  3ICK A;  3VJD A;  4KWD A;  3WEG A;  3WCL A;  2Z52 A;  1WMW A;  4JZB A;  4LFG A;  4RXA A;  4DZW A;  4JXN A;  3WJO A;  1V4E A;  3LOM A;  2OPN A;  3WEF A;  2E8V A;  2PS8 A;  5DGM F;  2Z50 A;  2PS4 A;  1V4J A;  2F8Z F;  3AQB B;  3LZ9 A;  4LIX A;  3AQC B;  1WKZ A;  2F7M F;  4E1E A;  4GA3 A;  3PYA A;  2E4O A;  5B0K A;  3RYE A;  1JFA A;  3OYR A;  3Q2Z A;  3WC9 A;  3V66 A;  5AHU B;  2PS7 A;  5B03 A;  3BNX A;  2PS6 A;  4KFA A;  3ID0 A;  3TC1 A;  3BNY A;  3KRA A;  5C05 A;  5ILI A;  3TFV A;  3ACW A;  5JUZ F;  4XQR F;  4JVJ F;  4KVD A;  3LDW A;  3ACY A;  4GP2 A;  1HXC A;  3DYF A;  3P41 A;  3VJ9 A;  4OKZ A;  5JV0 F;  3ZL6 A;  4KPD A;  4RXE A;  3SDU A;  5IL8 A;  2Z4Z A;  1N23 A;  4NFJ F;  2Q80 A;  2AEL A;  1YYR A;  3WJK A;  1PS1 A;  4QXS F;  3TS7 A;  3KRP A;  3N46 F;  3WCF A;  4JXY A;  1EZF A;  5KSX F;  5ILJ A;  4NFK F;  4L2X F;  1V4H A;  4LA5 A;  4OGU A;  5IKA A;  2I19 A;  3W7F A;  3OAB B;  3PYB A;  5AEL A;  5A0J A;  5E8H A;  5AFX A;  2J5C A;  2RAH A;  2ONH A;  2E8U A;  3VJA A;  1YJ4 A;  3AQ0 A;  3B7L A;  3APZ A;  3KBK A;  2AZL A;  2ZEU A;  3WCC A;  3AE0 A;  4EA2 A;  5IN8 A;  3LVS A;  4KQS A;  1VG2 A;  4DWG A;  5IK6 A;  3KRC B;  3WCG A;  3M02 A;  1WY0 A;  2J1P A;  3S9V A;  3NF2 A;  4LUU A;  4MC8 A;  1WL3 A;  4UMJ A;  3WEJ A;  3WCB A;  2OA6 A;  4NKF A;  1HM4 A;  3WJN A;  3WSA A;  4LTV A;  3NRI A;  3N1W F;  4EA1 A;  3OAC A;  3WCE A;  4H5E F;  4JYX A;  4DEM F;  3N49 F;  2Z7H A;  4KKM A;  4LTZ A;  2FOR A;  5IMI A;  5IMN A;  3DYH A;  5DJR F;  3P5P A;  1HX9 A;  3VJB A;  4H5D F;  4KQ5 A;  2F94 F;  3LG5 A;  1UBX A;  5ILK A;  3TFN A;  3Q30 A;  1YQ7 A;  4F6X A;  4LZ3 A;  4F62 A;  5B00 A;  3SDV A;  4F6V A;  3EGT A;  5CG6 A;  3QKC A;  2F89 F;  3IBA A;  5DJP F;  2E90 A;  2O1O A;  1YYT A;  3ACX A;  3WE9 A;  5ILH A;  3N1V F;  4DI5 A;  3P8L A;  3ICM A;  2ZCS A;  3ASX A;  2VF6 A;  5DHI A;  5IK9 A;  2J1O A;  3V1V A;  4EA0 A;  1UBW A;  2E91 A;  1UBV A;  1ZW5 A;  1N1B A;  4K10 A;  3PKO A;  5JA0 F;  4PVY F;  3LLW A;  3NPK A;  3Q2Q A;  4DWB A;  2Z4Y A;  5ERM A;  2Z7I A;  5DZ2 A;  3UCA A;  2OGD A;  3Q1O A;  2Z4W A;  2AZK A;  2DH4 A;  1N1Z A;  3ADZ A;  3VJ8 A;  4GAX A;  1RQJ A;  1VG4 A;  1YYQ A;  3RBM A;  3ZMC A;  4DXJ A;  3SDT A;  1HM7 A;  2AET A;  2EWG A;  3ZMB A;  5HN8 A;  4KK2 A;  3KRO B;  3LSN A;  5EAT A;  5E8K A;  5B0M A;  5HN7 A;  3CP6 A;  3WCA A;  4NKE A;  3M9U A;  1WL1 A;  5IKH A;  5H9D A;  3PDE A;  3WCM A;  4P0V A;  5A0K A;  4MC3 A;  5DIQ F;  3G4D A;  4P0W A;  3MAV A;  3LEE A;  2AEK A;  5B0J A;  2PS5 A;  4LZ0 A;  4LA6 A;  4KVY A;  3WSB A;  3ZOU A;  4LZC A;  4RNQ A;  5B02 A;  4LFV F;  2Q9Y A;  3OAC B;  4FP4 A;  4LLT A;  3WCJ A;  4KUX A;  3LGZ B;  1YYS A;  4OMG A;  5B0L A;  1YYU A;  3ICN A;  3SDQ A;  3LK5 A;  2ZEV A;  3KB9 A;  4HD1 A;  2Q9Z A;  3N3L F;  3N5H F;  4NG6 A;  2Z78 A;  4KVW A;  3OAB A;  1WL2 A;  3RMG A;  3N0G A;  5IK0 A;  5ER8 A;  3KRA B;  5DW7 A;  4LXW A;  4RXD A;  5B01 A;  1JFG A;  2H8O A;  4MC0 A;  3LGK A;  1VG7 A;  1VG3 A;  4N1Z F;  1YV5 A;  4LPH F;  3WCD A;  4XQT F;  2ZCR A;  5ILZ A;  3P8R A;  5ERO A;  2F92 F;  4KVI A;  2ZCO A;  4E9Z A;  4PVX F;  1YHL A;  5DGN F;  4LPG F;  2E94 A;  4LOB A;  3KRP B;  5DHK A;  3VJE A;  3KRC A;  4RYP A;  3KRF A;  4Q23 A;  4OMH A;  4RXC A;  3WCI A;  4WK5 A;  2F8C F;  4ZQ8 A;  1N21 A;  5HN9 A;  5DGS F;  5EAU A;  3M0G A;  4LLS A;  3MZV A;  3NPR A;  1VG6 A;  4N9U A;  3N5J F;  2E92 A;  2ZY1 A;  1YHK A;  4LFE A;  4FJQ A;  2F9K F;  2AZJ A;  5JV1 F;  4KPJ A;  1N20 A;  5HNA A;  5ILD A;  3WEH A;  3WEI A;  3G4F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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