1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords farnesyl pyrophosphate synthase
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
3VJDA 4NKFA 4MC0A 3S9VA 1EZFA 3ADZA 3B7LA 3ICZA 4KVDA 3LK5A 4LA6A 3UCAA 2E91A 5HN9A 2Q9YA 2E8VA 4LLSA 3Q2ZA 4MC3A 3QQVA 2ZY1A 5DJPF 5DGMF 5EROA 2ONGA 4KPJA 5IK6A 2E8XA 4LTVA 4KQ5A 4EA1A 5DJVF 3EFQA 3APZA 2J1PA 2PS7A 1V4IA 3ICNA 3TFNA 2E93A 2I19A 1PS1A 3IBAA 1RTRA 3VJ9A 1N1ZA 4E9UA 4LZ0A 3MZVA 1N1BA 2F94F 2VF6A 3KROA 4KQSA 4OKMA 4F62A 5KSXF 3VJAA 5IK9A 3PKOA 2PS8A 5C05A 2AELA 3N45F 3WCIA 2ZCRA 3OACB 5IN8A 3WC9A 2F89F 1VG4A 3WSAA 5B0JA 3NRIA 4Q23A 1UBVA 4PVYF 3Q2QA 5HN8A 3OYRA 3WEJA 1VG3A 3PH7A 3BNYA 3LZ9A 2O1OA 3WCFA 3KROB 3G4DA 4KKMA 3WEGA 3ZOUA 1YYTA 5ER8A 3WCLA 4JXYA 3ZMCA 2F8CF 4DEMF 5JUZF 3CKEA 3LJIA 3BNXA 4K10A 1UBYA 1WMWA 4JYXA 5HN7A 4DHDA 4LOBA 5JA0F 1RQIA 3WJNA 2FORA 5DHIA 4JVJF 1WKZA 4GA3A 5IK0A 3W7FA 3WCEA 1YV5A 1WL2A 2ZEVA 4RYPA 5B02A 2Z52A 1WY0A 4OGUA 4GP1A 5IMPA 3N5JF 3N3LF 2H8OA 3N0GA 5A0KA 3VJEA 4EA0A 3TFPA 3PYBA 4PVXF 5I1UA 3WSBA 4LPHF 5DW7A 1HXCA 4H5EF 1V4EA 1YHMA 3KRPA 3N49F 3Q1OA 3P8RA 4E1EA 3WJOA 3KRAB 3RYWA 2Q80A 3DYFA 4LFVF 1HXGA 3WCGA 3WEKA 3ICMA 4LZ3A 5AELA 1VG7A 4KQUA 5EAUA 1WL0A 4LTZA 1V4KA 3KRPB 1N22A 5ILZA 3AE0A 2AETA 2PS4A 3SDUA 1ZW5A 3ZCDA 3N46F 4UMJA 3WCHA 4RNQA 4EA2A 3WCJA 5AHUB 2ZCSA 4KK2A 4DXJA 3OACA 1YHLA 3KRCB 2OGDA 4OMHA 5ILKA 3N5HF 3M9UA 4KWDA 4KVYA 1VG2A 4DZWA 3AQCB 5EATA 3LGKA 4N1ZF 5DJRF 4LIXA 4GP2A 3LVSA 3ICKA 5DIQF 4LFEA 4RXCA 5E8KA 3TFVA 1VG6A 1V4HA 2Z50A 3WCBA 2E90A 2OPMA 2OA6A 5IL3A 3WJKA 1YHKA 3ASXA 3N1VF 2J5CA 3M02A 5E8LA 3S4JA 2ZEUA 4H5DF 3N3DA 5DHKA 5E8HA 4RXEA 2Z4XA 1YJ4A 5B00A 1DGPA 3ZL6A 4L2XF 4NFKF 4P0XA 4NG6A 1YQ7A 3LEEA 5ERNA 3WCMA 5CG5A 3M00A 4NKEA 3V1VA 2EWGA 2Q58A 3KRAA 3N0FA 4RXAA 3ID0A 3SDTA 3G4FA 2Z4WA 3DYHA 2DH4A 5IMIA 4WK5A 5IL8A 1YYUA 2AZLA 5ILDA 1JFAA 4KVWA 3ACWA 1N23A 2AEKA 2ZCOA 2F92F 4LA5A 1N24A 3SDVA 4FP4A 3NPRA 5DGSF 3P41A 4N9UA 4OMGA 3SDQA 3PYAA 5HNAA 3M0GA 1V4JA 2Z78A 4JZBA 1YYRA 5JV0F 3Q30A 4LFGA 4KUXA 1WL3A 1KIZA 3NF2A 3EGTA 3KRCA 2E94A 3OABB 5ILJA 4KFAA 3N1WF 5IVGA 4ZQ8A 5A0IA 5DGNF 3TC1A 5B03A 4DWGA 3AQ0A 5IMNA 1HXAA 4NUAA 4H5CF 3P5RA 5B0IA 2E92A 3WEIA 5B0MA 1HM7A 3LGZB 5ERMA 5JV1F 3V66A 3WEHA 1HM4A 3KRFB 4OKZA 5A0JA 3WCAA 2Q9ZA 2Z7IA 2Z4YA 3NPKA 4HD1A 3VJ8A 5IM1A 2E8TA 3M01A 5CG6A 2E8WA 4P0VA 3P8LA 2RAHA 1N21A 5DZ2A 2PS5A 4LXWA 3PDEA 2Z4VA 3EZ3A 2F9KF 2J1OA 4LZCA 3SAEA 5B01A 2OPNA 3KBKA 2ZCQA 1YYSA 3LDWA 4JZXA 2AZKA 3RBMA 3WCDA 3ACXA 3VJCA 4E9ZA 5IKAA 4QXSF 4QPFA 4LPGF 5B0LA 3N6KF 3WE9A 2P1CA 3P5PA 4FJQA 5AYPA 4DWBA 3DYGA 5ILHA 4RXDA 4XQTF 5ILYA 3QKCA 4NFIF 5H9DA 4P0WA 3LSNA 3LLWA 3RYEA 2Z4ZA 3ACYA 2QISA 5EASA 4XQSF 3LG5A 4DI5A 1RQJA 4MC8A 3RMGA 3IPIA 1FPSA 3WEFA 1HX9A 5AFXA 2ONHA 3WCCA 5IKHA 3MAVA 3CP6A 3CC9A 2E95A 4JXNA 2Z7HA 1UBXA 3OABA 3TS7A 1JFGA 4F6VA 1UBWA 4LUUA 4GAXA 5ILIA 4KPDA 4KVIA 3LOMA 4XQRF 3KRFA 3VJBA 4F6XA 1YYQA 3KB9A 1WL1A 4LLTA 3V1XA 5JV2F 2F7MF 5B0KA 4NFJF 2E8UA 2AZJA 1N20A 2PS6A 2E4OA 1KIYA 2FTZA 3LMDA 3ZMBA 1DI1A 3AQBB 3SDRA 2F8ZF
chains in the Genus database with same CATH superfamily
3VJDA 4NKFA 4MC0A 3S9VA 1EZFA 3ADZA 3B7LA 3ICZA 4KVDA 3LK5A 4LA6A 3UCAA 2E91A 5HN9A 2Q9YA 2E8VA 4LLSA 3Q2ZA 4MC3A 3QQVA 2ZY1A 5DJPF 5DGMF 5EROA 2ONGA 4KPJA 5IK6A 2E8XA 4LTVA 4KQ5A 4EA1A 5DJVF 3EFQA 3APZA 2J1PA 2PS7A 1V4IA 3ICNA 3TFNA 2E93A 2I19A 1PS1A 3IBAA 1RTRA 3VJ9A 1N1ZA 4E9UA 4LZ0A 3MZVA 1N1BA 2F94F 2VF6A 3KROA 4KQSA 4OKMA 4F62A 5KSXF 3VJAA 5IK9A 3PKOA 2PS8A 5C05A 2AELA 3N45F 3WCIA 2ZCRA 3OACB 5IN8A 3WC9A 2F89F 1VG4A 3WSAA 5B0JA 3NRIA 4Q23A 1UBVA 4PVYF 3Q2QA 5HN8A 3OYRA 3WEJA 1VG3A 3PH7A 3BNYA 3LZ9A 2O1OA 3WCFA 3KROB 3G4DA 4KKMA 3WEGA 3ZOUA 1YYTA 5ER8A 3WCLA 4JXYA 3ZMCA 2F8CF 4DEMF 5JUZF 3CKEA 3LJIA 3BNXA 4K10A 1UBYA 1WMWA 4JYXA 5HN7A 4DHDA 4LOBA 5JA0F 1RQIA 3WJNA 2FORA 5DHIA 4JVJF 1WKZA 4GA3A 5IK0A 3W7FA 3WCEA 1YV5A 1WL2A 2ZEVA 4RYPA 5B02A 2Z52A 1WY0A 4OGUA 4GP1A 5IMPA 3N5JF 3N3LF 2H8OA 3N0GA 5A0KA 3VJEA 4EA0A 3TFPA 3PYBA 4PVXF 5I1UA 3WSBA 4LPHF 5DW7A 1HXCA 4H5EF 1V4EA 1YHMA 3KRPA 3N49F 3Q1OA 3P8RA 4E1EA 3WJOA 3KRAB 3RYWA 2Q80A 3DYFA 4LFVF 1HXGA 3WCGA 3WEKA 3ICMA 4LZ3A 5AELA 1VG7A 4KQUA 5EAUA 1WL0A 4LTZA 1V4KA 3KRPB 1N22A 5ILZA 3AE0A 2AETA 2PS4A 3SDUA 1ZW5A 3ZCDA 3N46F 4UMJA 3WCHA 4RNQA 4EA2A 3WCJA 5AHUB 2ZCSA 4KK2A 4DXJA 3OACA 1YHLA 3KRCB 2OGDA 4OMHA 5ILKA 3N5HF 3M9UA 4KWDA 4KVYA 1VG2A 4DZWA 3AQCB 5EATA 3LGKA 4N1ZF 5DJRF 4LIXA 4GP2A 3LVSA 3ICKA 5DIQF 4LFEA 4RXCA 5E8KA 3TFVA 1VG6A 1V4HA 2Z50A 3WCBA 2E90A 2OPMA 2OA6A 5IL3A 3WJKA 1YHKA 3ASXA 3N1VF 2J5CA 3M02A 5E8LA 3S4JA 2ZEUA 4H5DF 3N3DA 5DHKA 5E8HA 4RXEA 2Z4XA 1YJ4A 5B00A 1DGPA 3ZL6A 4L2XF 4NFKF 4P0XA 4NG6A 1YQ7A 3LEEA 5ERNA 3WCMA 5CG5A 3M00A 4NKEA 3V1VA 2EWGA 2Q58A 3KRAA 3N0FA 4RXAA 3ID0A 3SDTA 3G4FA 2Z4WA 3DYHA 2DH4A 5IMIA 4WK5A 5IL8A 1YYUA 2AZLA 5ILDA 1JFAA 4KVWA 3ACWA 1N23A 2AEKA 2ZCOA 2F92F 4LA5A 1N24A 3SDVA 4FP4A 3NPRA 5DGSF 3P41A 4N9UA 4OMGA 3SDQA 3PYAA 5HNAA 3M0GA 1V4JA 2Z78A 4JZBA 1YYRA 5JV0F 3Q30A 4LFGA 4KUXA 1WL3A 1KIZA 3NF2A 3EGTA 3KRCA 2E94A 3OABB 5ILJA 4KFAA 3N1WF 5IVGA 4ZQ8A 5A0IA 5DGNF 3TC1A 5B03A 4DWGA 3AQ0A 5IMNA 1HXAA 4NUAA 4H5CF 3P5RA 5B0IA 2E92A 3WEIA 5B0MA 1HM7A 3LGZB 5ERMA 5JV1F 3V66A 3WEHA 1HM4A 3KRFB 4OKZA 5A0JA 3WCAA 2Q9ZA 2Z7IA 2Z4YA 3NPKA 4HD1A 3VJ8A 5IM1A 2E8TA 3M01A 5CG6A 2E8WA 4P0VA 3P8LA 2RAHA 1N21A 5DZ2A 2PS5A 4LXWA 3PDEA 2Z4VA 3EZ3A 2F9KF 2J1OA 4LZCA 3SAEA 5B01A 2OPNA 3KBKA 2ZCQA 1YYSA 3LDWA 4JZXA 2AZKA 3RBMA 3WCDA 3ACXA 3VJCA 4E9ZA 5IKAA 4QXSF 4QPFA 4LPGF 5B0LA 3N6KF 3WE9A 2P1CA 3P5PA 4FJQA 5AYPA 4DWBA 3DYGA 5ILHA 4RXDA 4XQTF 5ILYA 3QKCA 4NFIF 5H9DA 4P0WA 3LSNA 3LLWA 3RYEA 2Z4ZA 3ACYA 2QISA 5EASA 4XQSF 3LG5A 4DI5A 1RQJA 4MC8A 3RMGA 3IPIA 1FPSA 3WEFA 1HX9A 5AFXA 2ONHA 3WCCA 5IKHA 3MAVA 3CP6A 3CC9A 2E95A 4JXNA 2Z7HA 1UBXA 3OABA 3TS7A 1JFGA 4F6VA 1UBWA 4LUUA 4GAXA 5ILIA 4KPDA 4KVIA 3LOMA 4XQRF 3KRFA 3VJBA 4F6XA 1YYQA 3KB9A 1WL1A 4LLTA 3V1XA 5JV2F 2F7MF 5B0KA 4NFJF 2E8UA 2AZJA 1N20A 2PS6A 2E4OA 1KIYA 2FTZA 3LMDA 3ZMBA 1DI1A 3AQBB 3SDRA 2F8ZF
chains in the Genus database with same CATH topology
3VJDA 4NKFA 4MC0A 3S9VA 1EZFA 3ADZA 3B7LA 3ICZA 4KVDA 3LK5A 4LA6A 3UCAA 2E91A 5HN9A 2Q9YA 2E8VA 4LLSA 3Q2ZA 4MC3A 3QQVA 2ZY1A 5DJPF 5DGMF 5EROA 2ONGA 4KPJA 5IK6A 2E8XA 4LTVA 4KQ5A 4EA1A 5DJVF 3EFQA 3APZA 2J1PA 2PS7A 1V4IA 3ICNA 3TFNA 2E93A 2I19A 1PS1A 3IBAA 1RTRA 3VJ9A 1N1ZA 4E9UA 4LZ0A 3MZVA 1N1BA 2F94F 2VF6A 3KROA 4KQSA 4OKMA 4F62A 5KSXF 3VJAA 5IK9A 3PKOA 2PS8A 5C05A 2AELA 3N45F 3WCIA 2ZCRA 3OACB 5IN8A 3WC9A 2F89F 1VG4A 3WSAA 5B0JA 3NRIA 4Q23A 1UBVA 4PVYF 3Q2QA 5HN8A 3OYRA 3WEJA 1VG3A 3PH7A 3BNYA 3LZ9A 2O1OA 3WCFA 3KROB 3G4DA 4KKMA 3WEGA 3ZOUA 1YYTA 5ER8A 3WCLA 4JXYA 3ZMCA 2F8CF 4DEMF 5JUZF 3CKEA 3LJIA 3BNXA 4K10A 1UBYA 1WMWA 4JYXA 5HN7A 4DHDA 4LOBA 5JA0F 1RQIA 3WJNA 2FORA 5DHIA 4JVJF 1WKZA 4GA3A 5IK0A 3W7FA 3WCEA 1YV5A 1WL2A 2ZEVA 4RYPA 5B02A 2Z52A 1WY0A 4OGUA 4GP1A 5IMPA 3N5JF 3N3LF 2H8OA 3N0GA 5A0KA 3VJEA 4EA0A 3TFPA 3PYBA 4PVXF 5I1UA 3WSBA 4LPHF 5DW7A 1HXCA 4H5EF 1V4EA 1YHMA 3KRPA 3N49F 3Q1OA 3P8RA 4E1EA 3WJOA 3KRAB 3RYWA 2Q80A 3DYFA 4LFVF 1HXGA 3WCGA 3WEKA 3ICMA 4LZ3A 5AELA 1VG7A 4KQUA 5EAUA 1WL0A 4LTZA 1V4KA 3KRPB 1N22A 5ILZA 3AE0A 2AETA 2PS4A 3SDUA 1ZW5A 3ZCDA 3N46F 4UMJA 3WCHA 4RNQA 4EA2A 3WCJA 5AHUB 2ZCSA 4KK2A 4DXJA 3OACA 1YHLA 3KRCB 2OGDA 4OMHA 5ILKA 3N5HF 3M9UA 4KWDA 4KVYA 1VG2A 4DZWA 3AQCB 5EATA 3LGKA 4N1ZF 5DJRF 4LIXA 4GP2A 3LVSA 3ICKA 5DIQF 4LFEA 4RXCA 5E8KA 3TFVA 1VG6A 1V4HA 2Z50A 3WCBA 2E90A 2OPMA 2OA6A 5IL3A 3WJKA 1YHKA 3ASXA 3N1VF 2J5CA 3M02A 5E8LA 3S4JA 2ZEUA 4H5DF 3N3DA 5DHKA 5E8HA 4RXEA 2Z4XA 1YJ4A 5B00A 1DGPA 3ZL6A 4L2XF 4NFKF 4P0XA 4NG6A 1YQ7A 3LEEA 5ERNA 3WCMA 5CG5A 3M00A 4NKEA 3V1VA 2EWGA 2Q58A 3KRAA 3N0FA 4RXAA 3ID0A 3SDTA 3G4FA 2Z4WA 3DYHA 2DH4A 5IMIA 4WK5A 5IL8A 1YYUA 2AZLA 5ILDA 1JFAA 4KVWA 3ACWA 1N23A 2AEKA 2ZCOA 2F92F 4LA5A 1N24A 3SDVA 4FP4A 3NPRA 5DGSF 3P41A 4N9UA 4OMGA 3SDQA 3PYAA 5HNAA 3M0GA 1V4JA 2Z78A 4JZBA 1YYRA 5JV0F 3Q30A 4LFGA 4KUXA 1WL3A 1KIZA 3NF2A 3EGTA 3KRCA 2E94A 3OABB 5ILJA 4KFAA 3N1WF 5IVGA 4ZQ8A 5A0IA 5DGNF 3TC1A 5B03A 4DWGA 3AQ0A 5IMNA 1HXAA 4NUAA 4H5CF 3P5RA 5B0IA 2E92A 3WEIA 5B0MA 1HM7A 3LGZB 5ERMA 5JV1F 3V66A 3WEHA 1HM4A 3KRFB 4OKZA 5A0JA 3WCAA 2Q9ZA 2Z7IA 2Z4YA 3NPKA 4HD1A 3VJ8A 5IM1A 2E8TA 3M01A 5CG6A 2E8WA 4P0VA 3P8LA 2RAHA 1N21A 5DZ2A 2PS5A 4LXWA 3PDEA 2Z4VA 3EZ3A 2F9KF 2J1OA 4LZCA 3SAEA 5B01A 2OPNA 3KBKA 2ZCQA 1YYSA 3LDWA 4JZXA 2AZKA 3RBMA 3WCDA 3ACXA 3VJCA 4E9ZA 5IKAA 4QXSF 4QPFA 4LPGF 5B0LA 3N6KF 3WE9A 2P1CA 3P5PA 4FJQA 5AYPA 4DWBA 3DYGA 5ILHA 4RXDA 4XQTF 5ILYA 3QKCA 4NFIF 5H9DA 4P0WA 3LSNA 3LLWA 3RYEA 2Z4ZA 3ACYA 2QISA 5EASA 4XQSF 3LG5A 4DI5A 1RQJA 4MC8A 3RMGA 3IPIA 1FPSA 3WEFA 1HX9A 5AFXA 2ONHA 3WCCA 5IKHA 3MAVA 3CP6A 3CC9A 2E95A 4JXNA 2Z7HA 1UBXA 3OABA 3TS7A 1JFGA 4F6VA 1UBWA 4LUUA 4GAXA 5ILIA 4KPDA 4KVIA 3LOMA 4XQRF 3KRFA 3VJBA 4F6XA 1YYQA 3KB9A 1WL1A 4LLTA 3V1XA 5JV2F 2F7MF 5B0KA 4NFJF 2E8UA 2AZJA 1N20A 2PS6A 2E4OA 1KIYA 2FTZA 3LMDA 3ZMBA 1DI1A 3AQBB 3SDRA 2F8ZF
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3VJD A;  4NKF A;  4MC0 A;  3S9V A;  1EZF A;  3ADZ A;  3B7L A;  3ICZ A;  4KVD A;  3LK5 A;  4LA6 A;  3UCA A;  2E91 A;  5HN9 A;  2Q9Y A;  2E8V A;  4LLS A;  3Q2Z A;  4MC3 A;  3QQV A;  2ZY1 A;  5DJP F;  5DGM F;  5ERO A;  2ONG A;  4KPJ A;  5IK6 A;  2E8X A;  4LTV A;  4KQ5 A;  4EA1 A;  5DJV F;  3EFQ A;  3APZ A;  2J1P A;  2PS7 A;  1V4I A;  3ICN A;  3TFN A;  2E93 A;  2I19 A;  1PS1 A;  3IBA A;  1RTR A;  3VJ9 A;  1N1Z A;  4E9U A;  4LZ0 A;  3MZV A;  1N1B A;  2F94 F;  2VF6 A;  3KRO A;  4KQS A;  4OKM A;  4F62 A;  5KSX F;  3VJA A;  5IK9 A;  3PKO A;  2PS8 A;  5C05 A;  2AEL A;  3N45 F;  3WCI A;  2ZCR A;  3OAC B;  5IN8 A;  3WC9 A;  2F89 F;  1VG4 A;  3WSA A;  5B0J A;  3NRI A;  4Q23 A;  1UBV A;  4PVY F;  3Q2Q A;  5HN8 A;  3OYR A;  3WEJ A;  1VG3 A;  3PH7 A;  3BNY A;  3LZ9 A;  2O1O A;  3WCF A;  3KRO B;  3G4D A;  4KKM A;  3WEG A;  3ZOU A;  1YYT A;  5ER8 A;  3WCL A;  4JXY A;  3ZMC A;  2F8C F;  4DEM F;  5JUZ F;  3CKE A;  3LJI A;  3BNX A;  4K10 A;  1UBY A;  1WMW A;  4JYX A;  5HN7 A;  4DHD A;  4LOB A;  5JA0 F;  1RQI A;  3WJN A;  2FOR A;  5DHI A;  4JVJ F;  1WKZ A;  4GA3 A;  5IK0 A;  3W7F A;  3WCE A;  1YV5 A;  1WL2 A;  2ZEV A;  4RYP A;  5B02 A;  2Z52 A;  1WY0 A;  4OGU A;  4GP1 A;  5IMP A;  3N5J F;  3N3L F;  2H8O A;  3N0G A;  5A0K A;  3VJE A;  4EA0 A;  3TFP A;  3PYB A;  4PVX F;  5I1U A;  3WSB A;  4LPH F;  5DW7 A;  1HXC A;  4H5E F;  1V4E A;  1YHM A;  3KRP A;  3N49 F;  3Q1O A;  3P8R A;  4E1E A;  3WJO A;  3KRA B;  3RYW A;  2Q80 A;  3DYF A;  4LFV F;  1HXG A;  3WCG A;  3WEK A;  3ICM A;  4LZ3 A;  5AEL A;  1VG7 A;  4KQU A;  5EAU A;  1WL0 A;  4LTZ A;  1V4K A;  3KRP B;  1N22 A;  5ILZ A;  3AE0 A;  2AET A;  2PS4 A;  3SDU A;  1ZW5 A;  3ZCD A;  3N46 F;  4UMJ A;  3WCH A;  4RNQ A;  4EA2 A;  3WCJ A;  5AHU B;  2ZCS A;  4KK2 A;  4DXJ A;  3OAC A;  1YHL A;  3KRC B;  2OGD A;  4OMH A;  5ILK A;  3N5H F;  3M9U A;  4KWD A;  4KVY A;  1VG2 A;  4DZW A;  3AQC B;  5EAT A;  3LGK A;  4N1Z F;  5DJR F;  4LIX A;  4GP2 A;  3LVS A;  3ICK A;  5DIQ F;  4LFE A;  4RXC A;  5E8K A;  3TFV A;  1VG6 A;  1V4H A;  2Z50 A;  3WCB A;  2E90 A;  2OPM A;  2OA6 A;  5IL3 A;  3WJK A;  1YHK A;  3ASX A;  3N1V F;  2J5C A;  3M02 A;  5E8L A;  3S4J A;  2ZEU A;  4H5D F;  3N3D A;  5DHK A;  5E8H A;  4RXE A;  2Z4X A;  1YJ4 A;  5B00 A;  1DGP A;  3ZL6 A;  4L2X F;  4NFK F;  4P0X A;  4NG6 A;  1YQ7 A;  3LEE A;  5ERN A;  3WCM A;  5CG5 A;  3M00 A;  4NKE A;  3V1V A;  2EWG A;  2Q58 A;  3KRA A;  3N0F A;  4RXA A;  3ID0 A;  3SDT A;  3G4F A;  2Z4W A;  3DYH A;  2DH4 A;  5IMI A;  4WK5 A;  5IL8 A;  1YYU A;  2AZL A;  5ILD A;  1JFA A;  4KVW A;  3ACW A;  1N23 A;  2AEK A;  2ZCO A;  2F92 F;  4LA5 A;  1N24 A;  3SDV A;  4FP4 A;  3NPR A;  5DGS F;  3P41 A;  4N9U A;  4OMG A;  3SDQ A;  3PYA A;  5HNA A;  3M0G A;  1V4J A;  2Z78 A;  4JZB A;  1YYR A;  5JV0 F;  3Q30 A;  4LFG A;  4KUX A;  1WL3 A;  1KIZ A;  3NF2 A;  3EGT A;  3KRC A;  2E94 A;  3OAB B;  5ILJ A;  4KFA A;  3N1W F;  5IVG A;  4ZQ8 A;  5A0I A;  5DGN F;  3TC1 A;  5B03 A;  4DWG A;  3AQ0 A;  5IMN A;  1HXA A;  4NUA A;  4H5C F;  3P5R A;  5B0I A;  2E92 A;  3WEI A;  5B0M A;  1HM7 A;  3LGZ B;  5ERM A;  5JV1 F;  3V66 A;  3WEH A;  1HM4 A;  3KRF B;  4OKZ A;  5A0J A;  3WCA A;  2Q9Z A;  2Z7I A;  2Z4Y A;  3NPK A;  4HD1 A;  3VJ8 A;  5IM1 A;  2E8T A;  3M01 A;  5CG6 A;  2E8W A;  4P0V A;  3P8L A;  2RAH A;  1N21 A;  5DZ2 A;  2PS5 A;  4LXW A;  3PDE A;  2Z4V A;  3EZ3 A;  2F9K F;  2J1O A;  4LZC A;  3SAE A;  5B01 A;  2OPN A;  3KBK A;  2ZCQ A;  1YYS A;  3LDW A;  4JZX A;  2AZK A;  3RBM A;  3WCD A;  3ACX A;  3VJC A;  4E9Z A;  5IKA A;  4QXS F;  4QPF A;  4LPG F;  5B0L A;  3N6K F;  3WE9 A;  2P1C A;  3P5P A;  4FJQ A;  5AYP A;  4DWB A;  3DYG A;  5ILH A;  4RXD A;  4XQT F;  5ILY A;  3QKC A;  4NFI F;  5H9D A;  4P0W A;  3LSN A;  3LLW A;  3RYE A;  2Z4Z A;  3ACY A;  2QIS A;  5EAS A;  4XQS F;  3LG5 A;  4DI5 A;  1RQJ A;  4MC8 A;  3RMG A;  3IPI A;  1FPS A;  3WEF A;  1HX9 A;  5AFX A;  2ONH A;  3WCC A;  5IKH A;  3MAV A;  3CP6 A;  3CC9 A;  2E95 A;  4JXN A;  2Z7H A;  1UBX A;  3OAB A;  3TS7 A;  1JFG A;  4F6V A;  1UBW A;  4LUU A;  4GAX A;  5ILI A;  4KPD A;  4KVI A;  3LOM A;  4XQR F;  3KRF A;  3VJB A;  4F6X A;  1YYQ A;  3KB9 A;  1WL1 A;  4LLT A;  3V1X A;  5JV2 F;  2F7M F;  5B0K A;  4NFJ F;  2E8U A;  2AZJ A;  1N20 A;  2PS6 A;  2E4O A;  1KIY A;  2FTZ A;  3LMD A;  3ZMB A;  1DI1 A;  3AQB B;  3SDR A;  2F8Z F; 
#chains in the Genus database with same CATH topology
 3VJD A;  4NKF A;  4MC0 A;  3S9V A;  1EZF A;  3ADZ A;  3B7L A;  3ICZ A;  4KVD A;  3LK5 A;  4LA6 A;  3UCA A;  2E91 A;  5HN9 A;  2Q9Y A;  2E8V A;  4LLS A;  3Q2Z A;  4MC3 A;  3QQV A;  2ZY1 A;  5DJP F;  5DGM F;  5ERO A;  2ONG A;  4KPJ A;  5IK6 A;  2E8X A;  4LTV A;  4KQ5 A;  4EA1 A;  5DJV F;  3EFQ A;  3APZ A;  2J1P A;  2PS7 A;  1V4I A;  3ICN A;  3TFN A;  2E93 A;  2I19 A;  1PS1 A;  3IBA A;  1RTR A;  3VJ9 A;  1N1Z A;  4E9U A;  4LZ0 A;  3MZV A;  1N1B A;  2F94 F;  2VF6 A;  3KRO A;  4KQS A;  4OKM A;  4F62 A;  5KSX F;  3VJA A;  5IK9 A;  3PKO A;  2PS8 A;  5C05 A;  2AEL A;  3N45 F;  3WCI A;  2ZCR A;  3OAC B;  5IN8 A;  3WC9 A;  2F89 F;  1VG4 A;  3WSA A;  5B0J A;  3NRI A;  4Q23 A;  1UBV A;  4PVY F;  3Q2Q A;  5HN8 A;  3OYR A;  3WEJ A;  1VG3 A;  3PH7 A;  3BNY A;  3LZ9 A;  2O1O A;  3WCF A;  3KRO B;  3G4D A;  4KKM A;  3WEG A;  3ZOU A;  1YYT A;  5ER8 A;  3WCL A;  4JXY A;  3ZMC A;  2F8C F;  4DEM F;  5JUZ F;  3CKE A;  3LJI A;  3BNX A;  4K10 A;  1UBY A;  1WMW A;  4JYX A;  5HN7 A;  4DHD A;  4LOB A;  5JA0 F;  1RQI A;  3WJN A;  2FOR A;  5DHI A;  4JVJ F;  1WKZ A;  4GA3 A;  5IK0 A;  3W7F A;  3WCE A;  1YV5 A;  1WL2 A;  2ZEV A;  4RYP A;  5B02 A;  2Z52 A;  1WY0 A;  4OGU A;  4GP1 A;  5IMP A;  3N5J F;  3N3L F;  2H8O A;  3N0G A;  5A0K A;  3VJE A;  4EA0 A;  3TFP A;  3PYB A;  4PVX F;  5I1U A;  3WSB A;  4LPH F;  5DW7 A;  1HXC A;  4H5E F;  1V4E A;  1YHM A;  3KRP A;  3N49 F;  3Q1O A;  3P8R A;  4E1E A;  3WJO A;  3KRA B;  3RYW A;  2Q80 A;  3DYF A;  4LFV F;  1HXG A;  3WCG A;  3WEK A;  3ICM A;  4LZ3 A;  5AEL A;  1VG7 A;  4KQU A;  5EAU A;  1WL0 A;  4LTZ A;  1V4K A;  3KRP B;  1N22 A;  5ILZ A;  3AE0 A;  2AET A;  2PS4 A;  3SDU A;  1ZW5 A;  3ZCD A;  3N46 F;  4UMJ A;  3WCH A;  4RNQ A;  4EA2 A;  3WCJ A;  5AHU B;  2ZCS A;  4KK2 A;  4DXJ A;  3OAC A;  1YHL A;  3KRC B;  2OGD A;  4OMH A;  5ILK A;  3N5H F;  3M9U A;  4KWD A;  4KVY A;  1VG2 A;  4DZW A;  3AQC B;  5EAT A;  3LGK A;  4N1Z F;  5DJR F;  4LIX A;  4GP2 A;  3LVS A;  3ICK A;  5DIQ F;  4LFE A;  4RXC A;  5E8K A;  3TFV A;  1VG6 A;  1V4H A;  2Z50 A;  3WCB A;  2E90 A;  2OPM A;  2OA6 A;  5IL3 A;  3WJK A;  1YHK A;  3ASX A;  3N1V F;  2J5C A;  3M02 A;  5E8L A;  3S4J A;  2ZEU A;  4H5D F;  3N3D A;  5DHK A;  5E8H A;  4RXE A;  2Z4X A;  1YJ4 A;  5B00 A;  1DGP A;  3ZL6 A;  4L2X F;  4NFK F;  4P0X A;  4NG6 A;  1YQ7 A;  3LEE A;  5ERN A;  3WCM A;  5CG5 A;  3M00 A;  4NKE A;  3V1V A;  2EWG A;  2Q58 A;  3KRA A;  3N0F A;  4RXA A;  3ID0 A;  3SDT A;  3G4F A;  2Z4W A;  3DYH A;  2DH4 A;  5IMI A;  4WK5 A;  5IL8 A;  1YYU A;  2AZL A;  5ILD A;  1JFA A;  4KVW A;  3ACW A;  1N23 A;  2AEK A;  2ZCO A;  2F92 F;  4LA5 A;  1N24 A;  3SDV A;  4FP4 A;  3NPR A;  5DGS F;  3P41 A;  4N9U A;  4OMG A;  3SDQ A;  3PYA A;  5HNA A;  3M0G A;  1V4J A;  2Z78 A;  4JZB A;  1YYR A;  5JV0 F;  3Q30 A;  4LFG A;  4KUX A;  1WL3 A;  1KIZ A;  3NF2 A;  3EGT A;  3KRC A;  2E94 A;  3OAB B;  5ILJ A;  4KFA A;  3N1W F;  5IVG A;  4ZQ8 A;  5A0I A;  5DGN F;  3TC1 A;  5B03 A;  4DWG A;  3AQ0 A;  5IMN A;  1HXA A;  4NUA A;  4H5C F;  3P5R A;  5B0I A;  2E92 A;  3WEI A;  5B0M A;  1HM7 A;  3LGZ B;  5ERM A;  5JV1 F;  3V66 A;  3WEH A;  1HM4 A;  3KRF B;  4OKZ A;  5A0J A;  3WCA A;  2Q9Z A;  2Z7I A;  2Z4Y A;  3NPK A;  4HD1 A;  3VJ8 A;  5IM1 A;  2E8T A;  3M01 A;  5CG6 A;  2E8W A;  4P0V A;  3P8L A;  2RAH A;  1N21 A;  5DZ2 A;  2PS5 A;  4LXW A;  3PDE A;  2Z4V A;  3EZ3 A;  2F9K F;  2J1O A;  4LZC A;  3SAE A;  5B01 A;  2OPN A;  3KBK A;  2ZCQ A;  1YYS A;  3LDW A;  4JZX A;  2AZK A;  3RBM A;  3WCD A;  3ACX A;  3VJC A;  4E9Z A;  5IKA A;  4QXS F;  4QPF A;  4LPG F;  5B0L A;  3N6K F;  3WE9 A;  2P1C A;  3P5P A;  4FJQ A;  5AYP A;  4DWB A;  3DYG A;  5ILH A;  4RXD A;  4XQT F;  5ILY A;  3QKC A;  4NFI F;  5H9D A;  4P0W A;  3LSN A;  3LLW A;  3RYE A;  2Z4Z A;  3ACY A;  2QIS A;  5EAS A;  4XQS F;  3LG5 A;  4DI5 A;  1RQJ A;  4MC8 A;  3RMG A;  3IPI A;  1FPS A;  3WEF A;  1HX9 A;  5AFX A;  2ONH A;  3WCC A;  5IKH A;  3MAV A;  3CP6 A;  3CC9 A;  2E95 A;  4JXN A;  2Z7H A;  1UBX A;  3OAB A;  3TS7 A;  1JFG A;  4F6V A;  1UBW A;  4LUU A;  4GAX A;  5ILI A;  4KPD A;  4KVI A;  3LOM A;  4XQR F;  3KRF A;  3VJB A;  4F6X A;  1YYQ A;  3KB9 A;  1WL1 A;  4LLT A;  3V1X A;  5JV2 F;  2F7M F;  5B0K A;  4NFJ F;  2E8U A;  2AZJ A;  1N20 A;  2PS6 A;  2E4O A;  1KIY A;  2FTZ A;  3LMD A;  3ZMB A;  1DI1 A;  3AQB B;  3SDR A;  2F8Z F; 
#chains in the Genus database with same CATH homology
 3VJD A;  4NKF A;  4MC0 A;  3S9V A;  1EZF A;  3ADZ A;  3B7L A;  3ICZ A;  4KVD A;  3LK5 A;  4LA6 A;  3UCA A;  2E91 A;  5HN9 A;  2Q9Y A;  2E8V A;  4LLS A;  3Q2Z A;  4MC3 A;  3QQV A;  2ZY1 A;  5DJP F;  5DGM F;  5ERO A;  2ONG A;  4KPJ A;  5IK6 A;  2E8X A;  4LTV A;  4KQ5 A;  4EA1 A;  5DJV F;  3EFQ A;  3APZ A;  2J1P A;  2PS7 A;  1V4I A;  3ICN A;  3TFN A;  2E93 A;  2I19 A;  1PS1 A;  3IBA A;  1RTR A;  3VJ9 A;  1N1Z A;  4E9U A;  4LZ0 A;  3MZV A;  1N1B A;  2F94 F;  2VF6 A;  3KRO A;  4KQS A;  4OKM A;  4F62 A;  5KSX F;  3VJA A;  5IK9 A;  3PKO A;  2PS8 A;  5C05 A;  2AEL A;  3N45 F;  3WCI A;  2ZCR A;  3OAC B;  5IN8 A;  3WC9 A;  2F89 F;  1VG4 A;  3WSA A;  5B0J A;  3NRI A;  4Q23 A;  1UBV A;  4PVY F;  3Q2Q A;  5HN8 A;  3OYR A;  3WEJ A;  1VG3 A;  3PH7 A;  3BNY A;  3LZ9 A;  2O1O A;  3WCF A;  3KRO B;  3G4D A;  4KKM A;  3WEG A;  3ZOU A;  1YYT A;  5ER8 A;  3WCL A;  4JXY A;  3ZMC A;  2F8C F;  4DEM F;  5JUZ F;  3CKE A;  3LJI A;  3BNX A;  4K10 A;  1UBY A;  1WMW A;  4JYX A;  5HN7 A;  4DHD A;  4LOB A;  5JA0 F;  1RQI A;  3WJN A;  2FOR A;  5DHI A;  4JVJ F;  1WKZ A;  4GA3 A;  5IK0 A;  3W7F A;  3WCE A;  1YV5 A;  1WL2 A;  2ZEV A;  4RYP A;  5B02 A;  2Z52 A;  1WY0 A;  4OGU A;  4GP1 A;  5IMP A;  3N5J F;  3N3L F;  2H8O A;  3N0G A;  5A0K A;  3VJE A;  4EA0 A;  3TFP A;  3PYB A;  4PVX F;  5I1U A;  3WSB A;  4LPH F;  5DW7 A;  1HXC A;  4H5E F;  1V4E A;  1YHM A;  3KRP A;  3N49 F;  3Q1O A;  3P8R A;  4E1E A;  3WJO A;  3KRA B;  3RYW A;  2Q80 A;  3DYF A;  4LFV F;  1HXG A;  3WCG A;  3WEK A;  3ICM A;  4LZ3 A;  5AEL A;  1VG7 A;  4KQU A;  5EAU A;  1WL0 A;  4LTZ A;  1V4K A;  3KRP B;  1N22 A;  5ILZ A;  3AE0 A;  2AET A;  2PS4 A;  3SDU A;  1ZW5 A;  3ZCD A;  3N46 F;  4UMJ A;  3WCH A;  4RNQ A;  4EA2 A;  3WCJ A;  5AHU B;  2ZCS A;  4KK2 A;  4DXJ A;  3OAC A;  1YHL A;  3KRC B;  2OGD A;  4OMH A;  5ILK A;  3N5H F;  3M9U A;  4KWD A;  4KVY A;  1VG2 A;  4DZW A;  3AQC B;  5EAT A;  3LGK A;  4N1Z F;  5DJR F;  4LIX A;  4GP2 A;  3LVS A;  3ICK A;  5DIQ F;  4LFE A;  4RXC A;  5E8K A;  3TFV A;  1VG6 A;  1V4H A;  2Z50 A;  3WCB A;  2E90 A;  2OPM A;  2OA6 A;  5IL3 A;  3WJK A;  1YHK A;  3ASX A;  3N1V F;  2J5C A;  3M02 A;  5E8L A;  3S4J A;  2ZEU A;  4H5D F;  3N3D A;  5DHK A;  5E8H A;  4RXE A;  2Z4X A;  1YJ4 A;  5B00 A;  1DGP A;  3ZL6 A;  4L2X F;  4NFK F;  4P0X A;  4NG6 A;  1YQ7 A;  3LEE A;  5ERN A;  3WCM A;  5CG5 A;  3M00 A;  4NKE A;  3V1V A;  2EWG A;  2Q58 A;  3KRA A;  3N0F A;  4RXA A;  3ID0 A;  3SDT A;  3G4F A;  2Z4W A;  3DYH A;  2DH4 A;  5IMI A;  4WK5 A;  5IL8 A;  1YYU A;  2AZL A;  5ILD A;  1JFA A;  4KVW A;  3ACW A;  1N23 A;  2AEK A;  2ZCO A;  2F92 F;  4LA5 A;  1N24 A;  3SDV A;  4FP4 A;  3NPR A;  5DGS F;  3P41 A;  4N9U A;  4OMG A;  3SDQ A;  3PYA A;  5HNA A;  3M0G A;  1V4J A;  2Z78 A;  4JZB A;  1YYR A;  5JV0 F;  3Q30 A;  4LFG A;  4KUX A;  1WL3 A;  1KIZ A;  3NF2 A;  3EGT A;  3KRC A;  2E94 A;  3OAB B;  5ILJ A;  4KFA A;  3N1W F;  5IVG A;  4ZQ8 A;  5A0I A;  5DGN F;  3TC1 A;  5B03 A;  4DWG A;  3AQ0 A;  5IMN A;  1HXA A;  4NUA A;  4H5C F;  3P5R A;  5B0I A;  2E92 A;  3WEI A;  5B0M A;  1HM7 A;  3LGZ B;  5ERM A;  5JV1 F;  3V66 A;  3WEH A;  1HM4 A;  3KRF B;  4OKZ A;  5A0J A;  3WCA A;  2Q9Z A;  2Z7I A;  2Z4Y A;  3NPK A;  4HD1 A;  3VJ8 A;  5IM1 A;  2E8T A;  3M01 A;  5CG6 A;  2E8W A;  4P0V A;  3P8L A;  2RAH A;  1N21 A;  5DZ2 A;  2PS5 A;  4LXW A;  3PDE A;  2Z4V A;  3EZ3 A;  2F9K F;  2J1O A;  4LZC A;  3SAE A;  5B01 A;  2OPN A;  3KBK A;  2ZCQ A;  1YYS A;  3LDW A;  4JZX A;  2AZK A;  3RBM A;  3WCD A;  3ACX A;  3VJC A;  4E9Z A;  5IKA A;  4QXS F;  4QPF A;  4LPG F;  5B0L A;  3N6K F;  3WE9 A;  2P1C A;  3P5P A;  4FJQ A;  5AYP A;  4DWB A;  3DYG A;  5ILH A;  4RXD A;  4XQT F;  5ILY A;  3QKC A;  4NFI F;  5H9D A;  4P0W A;  3LSN A;  3LLW A;  3RYE A;  2Z4Z A;  3ACY A;  2QIS A;  5EAS A;  4XQS F;  3LG5 A;  4DI5 A;  1RQJ A;  4MC8 A;  3RMG A;  3IPI A;  1FPS A;  3WEF A;  1HX9 A;  5AFX A;  2ONH A;  3WCC A;  5IKH A;  3MAV A;  3CP6 A;  3CC9 A;  2E95 A;  4JXN A;  2Z7H A;  1UBX A;  3OAB A;  3TS7 A;  1JFG A;  4F6V A;  1UBW A;  4LUU A;  4GAX A;  5ILI A;  4KPD A;  4KVI A;  3LOM A;  4XQR F;  3KRF A;  3VJB A;  4F6X A;  1YYQ A;  3KB9 A;  1WL1 A;  4LLT A;  3V1X A;  5JV2 F;  2F7M F;  5B0K A;  4NFJ F;  2E8U A;  2AZJ A;  1N20 A;  2PS6 A;  2E4O A;  1KIY A;  2FTZ A;  3LMD A;  3ZMB A;  1DI1 A;  3AQB B;  3SDR A;  2F8Z F;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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