1YHMA

Structure of the complex of trypanosoma cruzi farnesyl disphosphate synthase with alendronate, isopentenyl diphosphate and mg+2
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords farnesyl pyrophosphate synthase
total genus 136
structure length 362
sequence length 362
chains with identical sequence B, C
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhmA00
1RQJA 4NUAA 4XQTF 3WCJA 2AZLA 4KVWA 3P5PA 5ILDA 4QPFA 1YQ7A 5KSXF 4E9ZA 3Q2QA 1YHLA 4OKMA 5ERNA 3RYEA 4UMJA 2Z7IA 2Q80A 5ILIA 3OABA 4LUUA 3N5HF 2Z4VA 2E93A 1KIZA 3V1VA 5DHIA 3VJEA 3WCDA 3G4FA 3KRFB 3WCGA 3N3LF 4KK2A 4DXJA 2F89F 1WL1A 2PS4A 2PS5A 4MC0A 4GAXA 4DZWA 3IBAA 1WL0A 5EASA 5IK6A 1JFGA 1FPSA 1V4JA 1WY0A 3WSAA 4LLSA 4HD1A 3CC9A 3KRAB 5JV0F 3M0GA 4LFEA 3WCFA 5H9DA 5IK0A 3M01A 3WEJA 1N21A 3ICMA 5B0LA 3WCHA 4DWGA 3WEIA 1V4HA 1N1BA 3N1WF 3LEEA 4K10A 4QXSF 3AQCB 5B0KA 4LZ0A 4DI5A 4KUXA 3ACWA 4LA6A 2OPNA 5JV1F 3CKEA 3LSNA 5HNAA 5DGMF 5EROA 2ZEUA 3B7LA 5JUZF 3DYHA 3ICKA 2DH4A 5DZ2A 2AELA 5E8LA 2O1OA 1YV5A 4P0WA 1YYUA 2I19A 4DHDA 1YYRA 1YHMA 3TS7A 2F94F 4XQRF 5AHUB 2J1PA 3N45F 2ONHA 2QISA 5E8HA 3KB9A 5DW7A 3S4JA 3OACB 3DYFA 4PVYF 2Q9ZA 5IL8A 4LZCA 3KRAA 5ERMA 4OMGA 1YHKA 2P1CA 4LPGF 3N1VF 5EAUA 4DEMF 3SDUA 4RNQA 1VG6A 4LFGA 1HM4A 4JZBA 4E9UA 4KKMA 4NFIF 3MAVA 3VJCA 1WL3A 4N9UA 3VJ8A 2E92A 3V1XA 3TFPA 2E8WA 4P0VA 5IVGA 2Z50A 3N49F 5DJRF 3EFQA 1RTRA 3PYBA 1HXCA 4RXDA 4RYPA 2ZCQA 3KROB 5ILZA 4JXYA 3KRCA 5IMPA 4F6VA 5HN8A 5CG5A 4F62A 3LMDA 4RXCA 3EZ3A 3WC9A 4FP4A 2E94A 3KBKA 5IKHA 4P0XA 3ICNA 3TC1A 4EA1A 3LK5A 2J1OA 2AZKA 4N1ZF 3BNXA 2Z78A 4OMHA 1N23A 5A0KA 3APZA 3ID0A 3WCMA 5JA0F 2OPMA 2Z4WA 3G4DA 5HN7A 2ZCSA 3WJKA 3WJNA 3KRPA 3ICZA 3LG5A 5DIQF 3TFNA 5IN8A 3N3DA 1WKZA 2E95A 2Q9YA 3S9VA 3IPIA 1V4KA 3ZOUA 1HXGA 1HX9A 4KQSA 1N1ZA 4GP1A 5ILKA 4JXNA 5B00A 2F8CF 3LDWA 5B0JA 4MC3A 2F9KF 3N46F 3ZL6A 3N6KF 4LLTA 2ZCRA 1UBYA 4ZQ8A 3NF2A 3LJIA 2E91A 4MC8A 3P41A 3DYGA 5B0MA 3KRFA 3SDTA 3VJAA 3WEFA 1UBVA 5ILHA 3OABB 3LZ9A 5AFXA 4KVDA 3Q2ZA 2J5CA 2AZJA 4LIXA 5AYPA 3VJ9A 2PS6A 5IM1A 2RAHA 3P8RA 3M02A 3WJOA 1V4EA 3LVSA 3P5RA 3CP6A 4NKFA 5I1UA 4RXEA 1ZW5A 3N5JF 3WSBA 4GA3A 5ILJA 3EGTA 4DWBA 3WCBA 4XQSF 4EA0A 2PS7A 2F8ZF 2E90A 3PKOA 3P8LA 2VF6A 4LPHF 4H5EF 3RMGA 3LLWA 5ER8A 4FJQA 5IK9A 4EA2A 4KPJA 4KPDA 2OA6A 4Q23A 2E8TA 4NFJF 4JYXA 3SDQA 3LGZB 5EATA 1HM7A 3VJDA 3ACXA 5E8KA 2PS8A 4NG6A 3VJBA 4E1EA 2E8UA 3SDVA 2E4OA 1PS1A 5IMNA 3WEHA 5B0IA 5IMIA 2AEKA 4PVXF 2FTZA 3SDRA 3WCIA 3Q30A 2ZY1A 3RYWA 3NRIA 4NKEA 3QQVA 3ADZA 5B02A 4JVJF 4KVIA 5AELA 3WCLA 3PH7A 4GP2A 3ACYA 3AE0A 3W7FA 5IL3A 3PYAA 2EWGA 3M00A 3OACA 1YYTA 1VG4A 1UBWA 5DJVF 4L2XF 1V4IA 4KFAA 3ZMCA 3ASXA 4H5CF 3N0FA 1YYQA 3LGKA 5DHKA 2Z7HA 4LZ3A 4LA5A 3AQBB 3NPRA 1HXAA 1UBXA 2F92F 2Z4YA 3AQ0A 3WCAA 4RXAA 2H8OA 1YJ4A 1KIYA 3MZVA 3NPKA 3RBMA 3SAEA 3OYRA 1DI1A 3KROA 5DJPF 5B03A 2F7MF 1N20A 4H5DF 2OGDA 5B01A 5HN9A 1EZFA 5C05A 2AETA 1RQIA 1N22A 5A0IA 4OKZA 3TFVA 1WMWA 1YYSA 4LTVA 3KRCB 5ILYA 3UCAA 2Z52A 4LTZA 4OGUA 3WE9A 3N0GA 3WCEA 4NFKF 3BNYA 5JV2F 3PDEA 4JZXA 3ZCDA 5DGSF 3ZMBA 3WEGA 5DGNF 1WL2A 2ONGA 3QKCA 4KQ5A 2FORA 4KWDA 1VG2A 3LOMA 3WEKA 1N24A 2ZCOA 4F6XA 4LOBA 4LFVF 5CG6A 2E8XA 2E8VA 2ZEVA 2Z4XA 3KRPB 1VG7A 3M9UA 1JFAA 5A0JA 3Q1OA 3WCCA 4WK5A 2Q58A 3V66A 2Z4ZA 4LXWA 5IKAA 1DGPA 4KVYA 4KQUA 1VG3A
chains in the Genus database with same CATH superfamily
1RQJA 4NUAA 4XQTF 3WCJA 2AZLA 4KVWA 3P5PA 5ILDA 4QPFA 1YQ7A 5KSXF 4E9ZA 3Q2QA 1YHLA 4OKMA 5ERNA 3RYEA 4UMJA 2Z7IA 2Q80A 5ILIA 3OABA 4LUUA 3N5HF 2Z4VA 2E93A 1KIZA 3V1VA 5DHIA 3VJEA 3WCDA 3G4FA 3KRFB 3WCGA 3N3LF 4KK2A 4DXJA 2F89F 1WL1A 2PS4A 2PS5A 4MC0A 4GAXA 4DZWA 3IBAA 1WL0A 5EASA 5IK6A 1JFGA 1FPSA 1V4JA 1WY0A 3WSAA 4LLSA 4HD1A 3CC9A 3KRAB 5JV0F 3M0GA 4LFEA 3WCFA 5H9DA 5IK0A 3M01A 3WEJA 1N21A 3ICMA 5B0LA 3WCHA 4DWGA 3WEIA 1V4HA 1N1BA 3N1WF 3LEEA 4K10A 4QXSF 3AQCB 5B0KA 4LZ0A 4DI5A 4KUXA 3ACWA 4LA6A 2OPNA 5JV1F 3CKEA 3LSNA 5HNAA 5DGMF 5EROA 2ZEUA 3B7LA 5JUZF 3DYHA 3ICKA 2DH4A 5DZ2A 2AELA 5E8LA 2O1OA 1YV5A 4P0WA 1YYUA 2I19A 4DHDA 1YYRA 1YHMA 3TS7A 2F94F 4XQRF 5AHUB 2J1PA 3N45F 2ONHA 2QISA 5E8HA 3KB9A 5DW7A 3S4JA 3OACB 3DYFA 4PVYF 2Q9ZA 5IL8A 4LZCA 3KRAA 5ERMA 4OMGA 1YHKA 2P1CA 4LPGF 3N1VF 5EAUA 4DEMF 3SDUA 4RNQA 1VG6A 4LFGA 1HM4A 4JZBA 4E9UA 4KKMA 4NFIF 3MAVA 3VJCA 1WL3A 4N9UA 3VJ8A 2E92A 3V1XA 3TFPA 2E8WA 4P0VA 5IVGA 2Z50A 3N49F 5DJRF 3EFQA 1RTRA 3PYBA 1HXCA 4RXDA 4RYPA 2ZCQA 3KROB 5ILZA 4JXYA 3KRCA 5IMPA 4F6VA 5HN8A 5CG5A 4F62A 3LMDA 4RXCA 3EZ3A 3WC9A 4FP4A 2E94A 3KBKA 5IKHA 4P0XA 3ICNA 3TC1A 4EA1A 3LK5A 2J1OA 2AZKA 4N1ZF 3BNXA 2Z78A 4OMHA 1N23A 5A0KA 3APZA 3ID0A 3WCMA 5JA0F 2OPMA 2Z4WA 3G4DA 5HN7A 2ZCSA 3WJKA 3WJNA 3KRPA 3ICZA 3LG5A 5DIQF 3TFNA 5IN8A 3N3DA 1WKZA 2E95A 2Q9YA 3S9VA 3IPIA 1V4KA 3ZOUA 1HXGA 1HX9A 4KQSA 1N1ZA 4GP1A 5ILKA 4JXNA 5B00A 2F8CF 3LDWA 5B0JA 4MC3A 2F9KF 3N46F 3ZL6A 3N6KF 4LLTA 2ZCRA 1UBYA 4ZQ8A 3NF2A 3LJIA 2E91A 4MC8A 3P41A 3DYGA 5B0MA 3KRFA 3SDTA 3VJAA 3WEFA 1UBVA 5ILHA 3OABB 3LZ9A 5AFXA 4KVDA 3Q2ZA 2J5CA 2AZJA 4LIXA 5AYPA 3VJ9A 2PS6A 5IM1A 2RAHA 3P8RA 3M02A 3WJOA 1V4EA 3LVSA 3P5RA 3CP6A 4NKFA 5I1UA 4RXEA 1ZW5A 3N5JF 3WSBA 4GA3A 5ILJA 3EGTA 4DWBA 3WCBA 4XQSF 4EA0A 2PS7A 2F8ZF 2E90A 3PKOA 3P8LA 2VF6A 4LPHF 4H5EF 3RMGA 3LLWA 5ER8A 4FJQA 5IK9A 4EA2A 4KPJA 4KPDA 2OA6A 4Q23A 2E8TA 4NFJF 4JYXA 3SDQA 3LGZB 5EATA 1HM7A 3VJDA 3ACXA 5E8KA 2PS8A 4NG6A 3VJBA 4E1EA 2E8UA 3SDVA 2E4OA 1PS1A 5IMNA 3WEHA 5B0IA 5IMIA 2AEKA 4PVXF 2FTZA 3SDRA 3WCIA 3Q30A 2ZY1A 3RYWA 3NRIA 4NKEA 3QQVA 3ADZA 5B02A 4JVJF 4KVIA 5AELA 3WCLA 3PH7A 4GP2A 3ACYA 3AE0A 3W7FA 5IL3A 3PYAA 2EWGA 3M00A 3OACA 1YYTA 1VG4A 1UBWA 5DJVF 4L2XF 1V4IA 4KFAA 3ZMCA 3ASXA 4H5CF 3N0FA 1YYQA 3LGKA 5DHKA 2Z7HA 4LZ3A 4LA5A 3AQBB 3NPRA 1HXAA 1UBXA 2F92F 2Z4YA 3AQ0A 3WCAA 4RXAA 2H8OA 1YJ4A 1KIYA 3MZVA 3NPKA 3RBMA 3SAEA 3OYRA 1DI1A 3KROA 5DJPF 5B03A 2F7MF 1N20A 4H5DF 2OGDA 5B01A 5HN9A 1EZFA 5C05A 2AETA 1RQIA 1N22A 5A0IA 4OKZA 3TFVA 1WMWA 1YYSA 4LTVA 3KRCB 5ILYA 3UCAA 2Z52A 4LTZA 4OGUA 3WE9A 3N0GA 3WCEA 4NFKF 3BNYA 5JV2F 3PDEA 4JZXA 3ZCDA 5DGSF 3ZMBA 3WEGA 5DGNF 1WL2A 2ONGA 3QKCA 4KQ5A 2FORA 4KWDA 1VG2A 3LOMA 3WEKA 1N24A 2ZCOA 4F6XA 4LOBA 4LFVF 5CG6A 2E8XA 2E8VA 2ZEVA 2Z4XA 3KRPB 1VG7A 3M9UA 1JFAA 5A0JA 3Q1OA 3WCCA 4WK5A 2Q58A 3V66A 2Z4ZA 4LXWA 5IKAA 1DGPA 4KVYA 4KQUA 1VG3A
chains in the Genus database with same CATH topology
1RQJA 4NUAA 4XQTF 3WCJA 2AZLA 4KVWA 3P5PA 5ILDA 4QPFA 1YQ7A 5KSXF 4E9ZA 3Q2QA 1YHLA 4OKMA 5ERNA 3RYEA 4UMJA 2Z7IA 2Q80A 5ILIA 3OABA 4LUUA 3N5HF 2Z4VA 2E93A 1KIZA 3V1VA 5DHIA 3VJEA 3WCDA 3G4FA 3KRFB 3WCGA 3N3LF 4KK2A 4DXJA 2F89F 1WL1A 2PS4A 2PS5A 4MC0A 4GAXA 4DZWA 3IBAA 1WL0A 5EASA 5IK6A 1JFGA 1FPSA 1V4JA 1WY0A 3WSAA 4LLSA 4HD1A 3CC9A 3KRAB 5JV0F 3M0GA 4LFEA 3WCFA 5H9DA 5IK0A 3M01A 3WEJA 1N21A 3ICMA 5B0LA 3WCHA 4DWGA 3WEIA 1V4HA 1N1BA 3N1WF 3LEEA 4K10A 4QXSF 3AQCB 5B0KA 4LZ0A 4DI5A 4KUXA 3ACWA 4LA6A 2OPNA 5JV1F 3CKEA 3LSNA 5HNAA 5DGMF 5EROA 2ZEUA 3B7LA 5JUZF 3DYHA 3ICKA 2DH4A 5DZ2A 2AELA 5E8LA 2O1OA 1YV5A 4P0WA 1YYUA 2I19A 4DHDA 1YYRA 1YHMA 3TS7A 2F94F 4XQRF 5AHUB 2J1PA 3N45F 2ONHA 2QISA 5E8HA 3KB9A 5DW7A 3S4JA 3OACB 3DYFA 4PVYF 2Q9ZA 5IL8A 4LZCA 3KRAA 5ERMA 4OMGA 1YHKA 2P1CA 4LPGF 3N1VF 5EAUA 4DEMF 3SDUA 4RNQA 1VG6A 4LFGA 1HM4A 4JZBA 4E9UA 4KKMA 4NFIF 3MAVA 3VJCA 1WL3A 4N9UA 3VJ8A 2E92A 3V1XA 3TFPA 2E8WA 4P0VA 5IVGA 2Z50A 3N49F 5DJRF 3EFQA 1RTRA 3PYBA 1HXCA 4RXDA 4RYPA 2ZCQA 3KROB 5ILZA 4JXYA 3KRCA 5IMPA 4F6VA 5HN8A 5CG5A 4F62A 3LMDA 4RXCA 3EZ3A 3WC9A 4FP4A 2E94A 3KBKA 5IKHA 4P0XA 3ICNA 3TC1A 4EA1A 3LK5A 2J1OA 2AZKA 4N1ZF 3BNXA 2Z78A 4OMHA 1N23A 5A0KA 3APZA 3ID0A 3WCMA 5JA0F 2OPMA 2Z4WA 3G4DA 5HN7A 2ZCSA 3WJKA 3WJNA 3KRPA 3ICZA 3LG5A 5DIQF 3TFNA 5IN8A 3N3DA 1WKZA 2E95A 2Q9YA 3S9VA 3IPIA 1V4KA 3ZOUA 1HXGA 1HX9A 4KQSA 1N1ZA 4GP1A 5ILKA 4JXNA 5B00A 2F8CF 3LDWA 5B0JA 4MC3A 2F9KF 3N46F 3ZL6A 3N6KF 4LLTA 2ZCRA 1UBYA 4ZQ8A 3NF2A 3LJIA 2E91A 4MC8A 3P41A 3DYGA 5B0MA 3KRFA 3SDTA 3VJAA 3WEFA 1UBVA 5ILHA 3OABB 3LZ9A 5AFXA 4KVDA 3Q2ZA 2J5CA 2AZJA 4LIXA 5AYPA 3VJ9A 2PS6A 5IM1A 2RAHA 3P8RA 3M02A 3WJOA 1V4EA 3LVSA 3P5RA 3CP6A 4NKFA 5I1UA 4RXEA 1ZW5A 3N5JF 3WSBA 4GA3A 5ILJA 3EGTA 4DWBA 3WCBA 4XQSF 4EA0A 2PS7A 2F8ZF 2E90A 3PKOA 3P8LA 2VF6A 4LPHF 4H5EF 3RMGA 3LLWA 5ER8A 4FJQA 5IK9A 4EA2A 4KPJA 4KPDA 2OA6A 4Q23A 2E8TA 4NFJF 4JYXA 3SDQA 3LGZB 5EATA 1HM7A 3VJDA 3ACXA 5E8KA 2PS8A 4NG6A 3VJBA 4E1EA 2E8UA 3SDVA 2E4OA 1PS1A 5IMNA 3WEHA 5B0IA 5IMIA 2AEKA 4PVXF 2FTZA 3SDRA 3WCIA 3Q30A 2ZY1A 3RYWA 3NRIA 4NKEA 3QQVA 3ADZA 5B02A 4JVJF 4KVIA 5AELA 3WCLA 3PH7A 4GP2A 3ACYA 3AE0A 3W7FA 5IL3A 3PYAA 2EWGA 3M00A 3OACA 1YYTA 1VG4A 1UBWA 5DJVF 4L2XF 1V4IA 4KFAA 3ZMCA 3ASXA 4H5CF 3N0FA 1YYQA 3LGKA 5DHKA 2Z7HA 4LZ3A 4LA5A 3AQBB 3NPRA 1HXAA 1UBXA 2F92F 2Z4YA 3AQ0A 3WCAA 4RXAA 2H8OA 1YJ4A 1KIYA 3MZVA 3NPKA 3RBMA 3SAEA 3OYRA 1DI1A 3KROA 5DJPF 5B03A 2F7MF 1N20A 4H5DF 2OGDA 5B01A 5HN9A 1EZFA 5C05A 2AETA 1RQIA 1N22A 5A0IA 4OKZA 3TFVA 1WMWA 1YYSA 4LTVA 3KRCB 5ILYA 3UCAA 2Z52A 4LTZA 4OGUA 3WE9A 3N0GA 3WCEA 4NFKF 3BNYA 5JV2F 3PDEA 4JZXA 3ZCDA 5DGSF 3ZMBA 3WEGA 5DGNF 1WL2A 2ONGA 3QKCA 4KQ5A 2FORA 4KWDA 1VG2A 3LOMA 3WEKA 1N24A 2ZCOA 4F6XA 4LOBA 4LFVF 5CG6A 2E8XA 2E8VA 2ZEVA 2Z4XA 3KRPB 1VG7A 3M9UA 1JFAA 5A0JA 3Q1OA 3WCCA 4WK5A 2Q58A 3V66A 2Z4ZA 4LXWA 5IKAA 1DGPA 4KVYA 4KQUA 1VG3A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1RQJ A;  4NUA A;  4XQT F;  3WCJ A;  2AZL A;  4KVW A;  3P5P A;  5ILD A;  4QPF A;  1YQ7 A;  5KSX F;  4E9Z A;  3Q2Q A;  1YHL A;  4OKM A;  5ERN A;  3RYE A;  4UMJ A;  2Z7I A;  2Q80 A;  5ILI A;  3OAB A;  4LUU A;  3N5H F;  2Z4V A;  2E93 A;  1KIZ A;  3V1V A;  5DHI A;  3VJE A;  3WCD A;  3G4F A;  3KRF B;  3WCG A;  3N3L F;  4KK2 A;  4DXJ A;  2F89 F;  1WL1 A;  2PS4 A;  2PS5 A;  4MC0 A;  4GAX A;  4DZW A;  3IBA A;  1WL0 A;  5EAS A;  5IK6 A;  1JFG A;  1FPS A;  1V4J A;  1WY0 A;  3WSA A;  4LLS A;  4HD1 A;  3CC9 A;  3KRA B;  5JV0 F;  3M0G A;  4LFE A;  3WCF A;  5H9D A;  5IK0 A;  3M01 A;  3WEJ A;  1N21 A;  3ICM A;  5B0L A;  3WCH A;  4DWG A;  3WEI A;  1V4H A;  1N1B A;  3N1W F;  3LEE A;  4K10 A;  4QXS F;  3AQC B;  5B0K A;  4LZ0 A;  4DI5 A;  4KUX A;  3ACW A;  4LA6 A;  2OPN A;  5JV1 F;  3CKE A;  3LSN A;  5HNA A;  5DGM F;  5ERO A;  2ZEU A;  3B7L A;  5JUZ F;  3DYH A;  3ICK A;  2DH4 A;  5DZ2 A;  2AEL A;  5E8L A;  2O1O A;  1YV5 A;  4P0W A;  1YYU A;  2I19 A;  4DHD A;  1YYR A;  1YHM A;  3TS7 A;  2F94 F;  4XQR F;  5AHU B;  2J1P A;  3N45 F;  2ONH A;  2QIS A;  5E8H A;  3KB9 A;  5DW7 A;  3S4J A;  3OAC B;  3DYF A;  4PVY F;  2Q9Z A;  5IL8 A;  4LZC A;  3KRA A;  5ERM A;  4OMG A;  1YHK A;  2P1C A;  4LPG F;  3N1V F;  5EAU A;  4DEM F;  3SDU A;  4RNQ A;  1VG6 A;  4LFG A;  1HM4 A;  4JZB A;  4E9U A;  4KKM A;  4NFI F;  3MAV A;  3VJC A;  1WL3 A;  4N9U A;  3VJ8 A;  2E92 A;  3V1X A;  3TFP A;  2E8W A;  4P0V A;  5IVG A;  2Z50 A;  3N49 F;  5DJR F;  3EFQ A;  1RTR A;  3PYB A;  1HXC A;  4RXD A;  4RYP A;  2ZCQ A;  3KRO B;  5ILZ A;  4JXY A;  3KRC A;  5IMP A;  4F6V A;  5HN8 A;  5CG5 A;  4F62 A;  3LMD A;  4RXC A;  3EZ3 A;  3WC9 A;  4FP4 A;  2E94 A;  3KBK A;  5IKH A;  4P0X A;  3ICN A;  3TC1 A;  4EA1 A;  3LK5 A;  2J1O A;  2AZK A;  4N1Z F;  3BNX A;  2Z78 A;  4OMH A;  1N23 A;  5A0K A;  3APZ A;  3ID0 A;  3WCM A;  5JA0 F;  2OPM A;  2Z4W A;  3G4D A;  5HN7 A;  2ZCS A;  3WJK A;  3WJN A;  3KRP A;  3ICZ A;  3LG5 A;  5DIQ F;  3TFN A;  5IN8 A;  3N3D A;  1WKZ A;  2E95 A;  2Q9Y A;  3S9V A;  3IPI A;  1V4K A;  3ZOU A;  1HXG A;  1HX9 A;  4KQS A;  1N1Z A;  4GP1 A;  5ILK A;  4JXN A;  5B00 A;  2F8C F;  3LDW A;  5B0J A;  4MC3 A;  2F9K F;  3N46 F;  3ZL6 A;  3N6K F;  4LLT A;  2ZCR A;  1UBY A;  4ZQ8 A;  3NF2 A;  3LJI A;  2E91 A;  4MC8 A;  3P41 A;  3DYG A;  5B0M A;  3KRF A;  3SDT A;  3VJA A;  3WEF A;  1UBV A;  5ILH A;  3OAB B;  3LZ9 A;  5AFX A;  4KVD A;  3Q2Z A;  2J5C A;  2AZJ A;  4LIX A;  5AYP A;  3VJ9 A;  2PS6 A;  5IM1 A;  2RAH A;  3P8R A;  3M02 A;  3WJO A;  1V4E A;  3LVS A;  3P5R A;  3CP6 A;  4NKF A;  5I1U A;  4RXE A;  1ZW5 A;  3N5J F;  3WSB A;  4GA3 A;  5ILJ A;  3EGT A;  4DWB A;  3WCB A;  4XQS F;  4EA0 A;  2PS7 A;  2F8Z F;  2E90 A;  3PKO A;  3P8L A;  2VF6 A;  4LPH F;  4H5E F;  3RMG A;  3LLW A;  5ER8 A;  4FJQ A;  5IK9 A;  4EA2 A;  4KPJ A;  4KPD A;  2OA6 A;  4Q23 A;  2E8T A;  4NFJ F;  4JYX A;  3SDQ A;  3LGZ B;  5EAT A;  1HM7 A;  3VJD A;  3ACX A;  5E8K A;  2PS8 A;  4NG6 A;  3VJB A;  4E1E A;  2E8U A;  3SDV A;  2E4O A;  1PS1 A;  5IMN A;  3WEH A;  5B0I A;  5IMI A;  2AEK A;  4PVX F;  2FTZ A;  3SDR A;  3WCI A;  3Q30 A;  2ZY1 A;  3RYW A;  3NRI A;  4NKE A;  3QQV A;  3ADZ A;  5B02 A;  4JVJ F;  4KVI A;  5AEL A;  3WCL A;  3PH7 A;  4GP2 A;  3ACY A;  3AE0 A;  3W7F A;  5IL3 A;  3PYA A;  2EWG A;  3M00 A;  3OAC A;  1YYT A;  1VG4 A;  1UBW A;  5DJV F;  4L2X F;  1V4I A;  4KFA A;  3ZMC A;  3ASX A;  4H5C F;  3N0F A;  1YYQ A;  3LGK A;  5DHK A;  2Z7H A;  4LZ3 A;  4LA5 A;  3AQB B;  3NPR A;  1HXA A;  1UBX A;  2F92 F;  2Z4Y A;  3AQ0 A;  3WCA A;  4RXA A;  2H8O A;  1YJ4 A;  1KIY A;  3MZV A;  3NPK A;  3RBM A;  3SAE A;  3OYR A;  1DI1 A;  3KRO A;  5DJP F;  5B03 A;  2F7M F;  1N20 A;  4H5D F;  2OGD A;  5B01 A;  5HN9 A;  1EZF A;  5C05 A;  2AET A;  1RQI A;  1N22 A;  5A0I A;  4OKZ A;  3TFV A;  1WMW A;  1YYS A;  4LTV A;  3KRC B;  5ILY A;  3UCA A;  2Z52 A;  4LTZ A;  4OGU A;  3WE9 A;  3N0G A;  3WCE A;  4NFK F;  3BNY A;  5JV2 F;  3PDE A;  4JZX A;  3ZCD A;  5DGS F;  3ZMB A;  3WEG A;  5DGN F;  1WL2 A;  2ONG A;  3QKC A;  4KQ5 A;  2FOR A;  4KWD A;  1VG2 A;  3LOM A;  3WEK A;  1N24 A;  2ZCO A;  4F6X A;  4LOB A;  4LFV F;  5CG6 A;  2E8X A;  2E8V A;  2ZEV A;  2Z4X A;  3KRP B;  1VG7 A;  3M9U A;  1JFA A;  5A0J A;  3Q1O A;  3WCC A;  4WK5 A;  2Q58 A;  3V66 A;  2Z4Z A;  4LXW A;  5IKA A;  1DGP A;  4KVY A;  4KQU A;  1VG3 A; 
#chains in the Genus database with same CATH topology
 1RQJ A;  4NUA A;  4XQT F;  3WCJ A;  2AZL A;  4KVW A;  3P5P A;  5ILD A;  4QPF A;  1YQ7 A;  5KSX F;  4E9Z A;  3Q2Q A;  1YHL A;  4OKM A;  5ERN A;  3RYE A;  4UMJ A;  2Z7I A;  2Q80 A;  5ILI A;  3OAB A;  4LUU A;  3N5H F;  2Z4V A;  2E93 A;  1KIZ A;  3V1V A;  5DHI A;  3VJE A;  3WCD A;  3G4F A;  3KRF B;  3WCG A;  3N3L F;  4KK2 A;  4DXJ A;  2F89 F;  1WL1 A;  2PS4 A;  2PS5 A;  4MC0 A;  4GAX A;  4DZW A;  3IBA A;  1WL0 A;  5EAS A;  5IK6 A;  1JFG A;  1FPS A;  1V4J A;  1WY0 A;  3WSA A;  4LLS A;  4HD1 A;  3CC9 A;  3KRA B;  5JV0 F;  3M0G A;  4LFE A;  3WCF A;  5H9D A;  5IK0 A;  3M01 A;  3WEJ A;  1N21 A;  3ICM A;  5B0L A;  3WCH A;  4DWG A;  3WEI A;  1V4H A;  1N1B A;  3N1W F;  3LEE A;  4K10 A;  4QXS F;  3AQC B;  5B0K A;  4LZ0 A;  4DI5 A;  4KUX A;  3ACW A;  4LA6 A;  2OPN A;  5JV1 F;  3CKE A;  3LSN A;  5HNA A;  5DGM F;  5ERO A;  2ZEU A;  3B7L A;  5JUZ F;  3DYH A;  3ICK A;  2DH4 A;  5DZ2 A;  2AEL A;  5E8L A;  2O1O A;  1YV5 A;  4P0W A;  1YYU A;  2I19 A;  4DHD A;  1YYR A;  1YHM A;  3TS7 A;  2F94 F;  4XQR F;  5AHU B;  2J1P A;  3N45 F;  2ONH A;  2QIS A;  5E8H A;  3KB9 A;  5DW7 A;  3S4J A;  3OAC B;  3DYF A;  4PVY F;  2Q9Z A;  5IL8 A;  4LZC A;  3KRA A;  5ERM A;  4OMG A;  1YHK A;  2P1C A;  4LPG F;  3N1V F;  5EAU A;  4DEM F;  3SDU A;  4RNQ A;  1VG6 A;  4LFG A;  1HM4 A;  4JZB A;  4E9U A;  4KKM A;  4NFI F;  3MAV A;  3VJC A;  1WL3 A;  4N9U A;  3VJ8 A;  2E92 A;  3V1X A;  3TFP A;  2E8W A;  4P0V A;  5IVG A;  2Z50 A;  3N49 F;  5DJR F;  3EFQ A;  1RTR A;  3PYB A;  1HXC A;  4RXD A;  4RYP A;  2ZCQ A;  3KRO B;  5ILZ A;  4JXY A;  3KRC A;  5IMP A;  4F6V A;  5HN8 A;  5CG5 A;  4F62 A;  3LMD A;  4RXC A;  3EZ3 A;  3WC9 A;  4FP4 A;  2E94 A;  3KBK A;  5IKH A;  4P0X A;  3ICN A;  3TC1 A;  4EA1 A;  3LK5 A;  2J1O A;  2AZK A;  4N1Z F;  3BNX A;  2Z78 A;  4OMH A;  1N23 A;  5A0K A;  3APZ A;  3ID0 A;  3WCM A;  5JA0 F;  2OPM A;  2Z4W A;  3G4D A;  5HN7 A;  2ZCS A;  3WJK A;  3WJN A;  3KRP A;  3ICZ A;  3LG5 A;  5DIQ F;  3TFN A;  5IN8 A;  3N3D A;  1WKZ A;  2E95 A;  2Q9Y A;  3S9V A;  3IPI A;  1V4K A;  3ZOU A;  1HXG A;  1HX9 A;  4KQS A;  1N1Z A;  4GP1 A;  5ILK A;  4JXN A;  5B00 A;  2F8C F;  3LDW A;  5B0J A;  4MC3 A;  2F9K F;  3N46 F;  3ZL6 A;  3N6K F;  4LLT A;  2ZCR A;  1UBY A;  4ZQ8 A;  3NF2 A;  3LJI A;  2E91 A;  4MC8 A;  3P41 A;  3DYG A;  5B0M A;  3KRF A;  3SDT A;  3VJA A;  3WEF A;  1UBV A;  5ILH A;  3OAB B;  3LZ9 A;  5AFX A;  4KVD A;  3Q2Z A;  2J5C A;  2AZJ A;  4LIX A;  5AYP A;  3VJ9 A;  2PS6 A;  5IM1 A;  2RAH A;  3P8R A;  3M02 A;  3WJO A;  1V4E A;  3LVS A;  3P5R A;  3CP6 A;  4NKF A;  5I1U A;  4RXE A;  1ZW5 A;  3N5J F;  3WSB A;  4GA3 A;  5ILJ A;  3EGT A;  4DWB A;  3WCB A;  4XQS F;  4EA0 A;  2PS7 A;  2F8Z F;  2E90 A;  3PKO A;  3P8L A;  2VF6 A;  4LPH F;  4H5E F;  3RMG A;  3LLW A;  5ER8 A;  4FJQ A;  5IK9 A;  4EA2 A;  4KPJ A;  4KPD A;  2OA6 A;  4Q23 A;  2E8T A;  4NFJ F;  4JYX A;  3SDQ A;  3LGZ B;  5EAT A;  1HM7 A;  3VJD A;  3ACX A;  5E8K A;  2PS8 A;  4NG6 A;  3VJB A;  4E1E A;  2E8U A;  3SDV A;  2E4O A;  1PS1 A;  5IMN A;  3WEH A;  5B0I A;  5IMI A;  2AEK A;  4PVX F;  2FTZ A;  3SDR A;  3WCI A;  3Q30 A;  2ZY1 A;  3RYW A;  3NRI A;  4NKE A;  3QQV A;  3ADZ A;  5B02 A;  4JVJ F;  4KVI A;  5AEL A;  3WCL A;  3PH7 A;  4GP2 A;  3ACY A;  3AE0 A;  3W7F A;  5IL3 A;  3PYA A;  2EWG A;  3M00 A;  3OAC A;  1YYT A;  1VG4 A;  1UBW A;  5DJV F;  4L2X F;  1V4I A;  4KFA A;  3ZMC A;  3ASX A;  4H5C F;  3N0F A;  1YYQ A;  3LGK A;  5DHK A;  2Z7H A;  4LZ3 A;  4LA5 A;  3AQB B;  3NPR A;  1HXA A;  1UBX A;  2F92 F;  2Z4Y A;  3AQ0 A;  3WCA A;  4RXA A;  2H8O A;  1YJ4 A;  1KIY A;  3MZV A;  3NPK A;  3RBM A;  3SAE A;  3OYR A;  1DI1 A;  3KRO A;  5DJP F;  5B03 A;  2F7M F;  1N20 A;  4H5D F;  2OGD A;  5B01 A;  5HN9 A;  1EZF A;  5C05 A;  2AET A;  1RQI A;  1N22 A;  5A0I A;  4OKZ A;  3TFV A;  1WMW A;  1YYS A;  4LTV A;  3KRC B;  5ILY A;  3UCA A;  2Z52 A;  4LTZ A;  4OGU A;  3WE9 A;  3N0G A;  3WCE A;  4NFK F;  3BNY A;  5JV2 F;  3PDE A;  4JZX A;  3ZCD A;  5DGS F;  3ZMB A;  3WEG A;  5DGN F;  1WL2 A;  2ONG A;  3QKC A;  4KQ5 A;  2FOR A;  4KWD A;  1VG2 A;  3LOM A;  3WEK A;  1N24 A;  2ZCO A;  4F6X A;  4LOB A;  4LFV F;  5CG6 A;  2E8X A;  2E8V A;  2ZEV A;  2Z4X A;  3KRP B;  1VG7 A;  3M9U A;  1JFA A;  5A0J A;  3Q1O A;  3WCC A;  4WK5 A;  2Q58 A;  3V66 A;  2Z4Z A;  4LXW A;  5IKA A;  1DGP A;  4KVY A;  4KQU A;  1VG3 A; 
#chains in the Genus database with same CATH homology
 1RQJ A;  4NUA A;  4XQT F;  3WCJ A;  2AZL A;  4KVW A;  3P5P A;  5ILD A;  4QPF A;  1YQ7 A;  5KSX F;  4E9Z A;  3Q2Q A;  1YHL A;  4OKM A;  5ERN A;  3RYE A;  4UMJ A;  2Z7I A;  2Q80 A;  5ILI A;  3OAB A;  4LUU A;  3N5H F;  2Z4V A;  2E93 A;  1KIZ A;  3V1V A;  5DHI A;  3VJE A;  3WCD A;  3G4F A;  3KRF B;  3WCG A;  3N3L F;  4KK2 A;  4DXJ A;  2F89 F;  1WL1 A;  2PS4 A;  2PS5 A;  4MC0 A;  4GAX A;  4DZW A;  3IBA A;  1WL0 A;  5EAS A;  5IK6 A;  1JFG A;  1FPS A;  1V4J A;  1WY0 A;  3WSA A;  4LLS A;  4HD1 A;  3CC9 A;  3KRA B;  5JV0 F;  3M0G A;  4LFE A;  3WCF A;  5H9D A;  5IK0 A;  3M01 A;  3WEJ A;  1N21 A;  3ICM A;  5B0L A;  3WCH A;  4DWG A;  3WEI A;  1V4H A;  1N1B A;  3N1W F;  3LEE A;  4K10 A;  4QXS F;  3AQC B;  5B0K A;  4LZ0 A;  4DI5 A;  4KUX A;  3ACW A;  4LA6 A;  2OPN A;  5JV1 F;  3CKE A;  3LSN A;  5HNA A;  5DGM F;  5ERO A;  2ZEU A;  3B7L A;  5JUZ F;  3DYH A;  3ICK A;  2DH4 A;  5DZ2 A;  2AEL A;  5E8L A;  2O1O A;  1YV5 A;  4P0W A;  1YYU A;  2I19 A;  4DHD A;  1YYR A;  1YHM A;  3TS7 A;  2F94 F;  4XQR F;  5AHU B;  2J1P A;  3N45 F;  2ONH A;  2QIS A;  5E8H A;  3KB9 A;  5DW7 A;  3S4J A;  3OAC B;  3DYF A;  4PVY F;  2Q9Z A;  5IL8 A;  4LZC A;  3KRA A;  5ERM A;  4OMG A;  1YHK A;  2P1C A;  4LPG F;  3N1V F;  5EAU A;  4DEM F;  3SDU A;  4RNQ A;  1VG6 A;  4LFG A;  1HM4 A;  4JZB A;  4E9U A;  4KKM A;  4NFI F;  3MAV A;  3VJC A;  1WL3 A;  4N9U A;  3VJ8 A;  2E92 A;  3V1X A;  3TFP A;  2E8W A;  4P0V A;  5IVG A;  2Z50 A;  3N49 F;  5DJR F;  3EFQ A;  1RTR A;  3PYB A;  1HXC A;  4RXD A;  4RYP A;  2ZCQ A;  3KRO B;  5ILZ A;  4JXY A;  3KRC A;  5IMP A;  4F6V A;  5HN8 A;  5CG5 A;  4F62 A;  3LMD A;  4RXC A;  3EZ3 A;  3WC9 A;  4FP4 A;  2E94 A;  3KBK A;  5IKH A;  4P0X A;  3ICN A;  3TC1 A;  4EA1 A;  3LK5 A;  2J1O A;  2AZK A;  4N1Z F;  3BNX A;  2Z78 A;  4OMH A;  1N23 A;  5A0K A;  3APZ A;  3ID0 A;  3WCM A;  5JA0 F;  2OPM A;  2Z4W A;  3G4D A;  5HN7 A;  2ZCS A;  3WJK A;  3WJN A;  3KRP A;  3ICZ A;  3LG5 A;  5DIQ F;  3TFN A;  5IN8 A;  3N3D A;  1WKZ A;  2E95 A;  2Q9Y A;  3S9V A;  3IPI A;  1V4K A;  3ZOU A;  1HXG A;  1HX9 A;  4KQS A;  1N1Z A;  4GP1 A;  5ILK A;  4JXN A;  5B00 A;  2F8C F;  3LDW A;  5B0J A;  4MC3 A;  2F9K F;  3N46 F;  3ZL6 A;  3N6K F;  4LLT A;  2ZCR A;  1UBY A;  4ZQ8 A;  3NF2 A;  3LJI A;  2E91 A;  4MC8 A;  3P41 A;  3DYG A;  5B0M A;  3KRF A;  3SDT A;  3VJA A;  3WEF A;  1UBV A;  5ILH A;  3OAB B;  3LZ9 A;  5AFX A;  4KVD A;  3Q2Z A;  2J5C A;  2AZJ A;  4LIX A;  5AYP A;  3VJ9 A;  2PS6 A;  5IM1 A;  2RAH A;  3P8R A;  3M02 A;  3WJO A;  1V4E A;  3LVS A;  3P5R A;  3CP6 A;  4NKF A;  5I1U A;  4RXE A;  1ZW5 A;  3N5J F;  3WSB A;  4GA3 A;  5ILJ A;  3EGT A;  4DWB A;  3WCB A;  4XQS F;  4EA0 A;  2PS7 A;  2F8Z F;  2E90 A;  3PKO A;  3P8L A;  2VF6 A;  4LPH F;  4H5E F;  3RMG A;  3LLW A;  5ER8 A;  4FJQ A;  5IK9 A;  4EA2 A;  4KPJ A;  4KPD A;  2OA6 A;  4Q23 A;  2E8T A;  4NFJ F;  4JYX A;  3SDQ A;  3LGZ B;  5EAT A;  1HM7 A;  3VJD A;  3ACX A;  5E8K A;  2PS8 A;  4NG6 A;  3VJB A;  4E1E A;  2E8U A;  3SDV A;  2E4O A;  1PS1 A;  5IMN A;  3WEH A;  5B0I A;  5IMI A;  2AEK A;  4PVX F;  2FTZ A;  3SDR A;  3WCI A;  3Q30 A;  2ZY1 A;  3RYW A;  3NRI A;  4NKE A;  3QQV A;  3ADZ A;  5B02 A;  4JVJ F;  4KVI A;  5AEL A;  3WCL A;  3PH7 A;  4GP2 A;  3ACY A;  3AE0 A;  3W7F A;  5IL3 A;  3PYA A;  2EWG A;  3M00 A;  3OAC A;  1YYT A;  1VG4 A;  1UBW A;  5DJV F;  4L2X F;  1V4I A;  4KFA A;  3ZMC A;  3ASX A;  4H5C F;  3N0F A;  1YYQ A;  3LGK A;  5DHK A;  2Z7H A;  4LZ3 A;  4LA5 A;  3AQB B;  3NPR A;  1HXA A;  1UBX A;  2F92 F;  2Z4Y A;  3AQ0 A;  3WCA A;  4RXA A;  2H8O A;  1YJ4 A;  1KIY A;  3MZV A;  3NPK A;  3RBM A;  3SAE A;  3OYR A;  1DI1 A;  3KRO A;  5DJP F;  5B03 A;  2F7M F;  1N20 A;  4H5D F;  2OGD A;  5B01 A;  5HN9 A;  1EZF A;  5C05 A;  2AET A;  1RQI A;  1N22 A;  5A0I A;  4OKZ A;  3TFV A;  1WMW A;  1YYS A;  4LTV A;  3KRC B;  5ILY A;  3UCA A;  2Z52 A;  4LTZ A;  4OGU A;  3WE9 A;  3N0G A;  3WCE A;  4NFK F;  3BNY A;  5JV2 F;  3PDE A;  4JZX A;  3ZCD A;  5DGS F;  3ZMB A;  3WEG A;  5DGN F;  1WL2 A;  2ONG A;  3QKC A;  4KQ5 A;  2FOR A;  4KWD A;  1VG2 A;  3LOM A;  3WEK A;  1N24 A;  2ZCO A;  4F6X A;  4LOB A;  4LFV F;  5CG6 A;  2E8X A;  2E8V A;  2ZEV A;  2Z4X A;  3KRP B;  1VG7 A;  3M9U A;  1JFA A;  5A0J A;  3Q1O A;  3WCC A;  4WK5 A;  2Q58 A;  3V66 A;  2Z4Z A;  4LXW A;  5IKA A;  1DGP A;  4KVY A;  4KQU A;  1VG3 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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