1RQJA

Active conformation of farnesyl pyrophosphate synthase bound to isopentyl pyrophosphate and risedronate
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
299
structure length
299
Chain Sequence
MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQALDLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLAFQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQLAEQSLDTSALEALADYIIQRNK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for bisphosphonate-mediated inhibition of isoprenoid biosynthesis
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords Geranyltranstransferase
total genus 126
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2003-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1rqjA00
3LDWA 2F89F 5JA0F 5B0JA 1UBWA 1WY0A 4WK5A 1HXAA 3B7LA 4GAXA 4KK2A 3OACB 4ZQ8A 4LZCA 1YJ4A 3AQ0A 4LTZA 1N24A 4GP2A 4KPDA 3WCDA 4RXAA 3KRPA 4KQUA 3VJBA 1RQIA 5DHKA 1N22A 2F8ZF 3S4JA 1YV5A 1RTRA 2OA6A 4LFGA 5IN8A 3LG5A 3MZVA 5EATA 3P5RA 1EZFA 4DWGA 4DXJA 3P8RA 3N6KF 5B02A 2OPMA 3IBAA 1FPSA 3N0FA 3WCMA 5DJRF 5ILZA 1VG3A 3ACXA 4LXWA 3WC9A 5B0KA 1V4KA 3WEHA 1JFAA 1WL2A 2AZKA 4LFVF 2E90A 3N1VF 3SDRA 4P0WA 5IL8A 4KVDA 1WL1A 3EGTA 4KKMA 4KVIA 3RBMA 5HNAA 3LEEA 3M9UA 2Z78A 4NG6A 5DGSF 2E94A 2F94F 3V1VA 3OABB 3WSBA 3KRAB 3WCGA 3N46F 3ZMBA 3LSNA 4LPGF 2Z4ZA 3N5HF 3KRCA 5KSXF 4JZXA 2PS6A 1HM7A 4LLTA 1WL3A 5IK6A 2E8WA 3EZ3A 2H8OA 2E93A 5ER8A 3WEIA 3WJOA 3VJAA 2VF6A 4FJQA 3CC9A 5B00A 3G4FA 2Q80A 5AHUB 3BNYA 3N0GA 5ILKA 4JXYA 4EA1A 1YYTA 2AZJA 3ACYA 2Z4YA 5DJVF 2ZEVA 2AETA 4FP4A 4RNQA 2ZCQA 4L2XF 4H5DF 4RXEA 3PYBA 3LLWA 1YHMA 3V66A 3LMDA 2Z4XA 2FORA 5H9DA 4HD1A 3RYWA 2Z50A 4LUUA 5JV1F 4PVYF 2Z7IA 1YYRA 3WEJA 3AQCB 1WL0A 3KROA 1UBYA 5JV2F 4LPHF 4JZBA 2AELA 2PS4A 1N20A 4RYPA 5DIQF 4NUAA 3SAEA 1V4JA 3WEKA 3N3LF 2E8VA 3WCFA 2E95A 3ZOUA 5ILHA 1YQ7A 3VJ8A 3WSAA 2FTZA 3P8LA 4JYXA 2E92A 3N5JF 1DGPA 4E9ZA 4LIXA 3WJNA 3NRIA 5AFXA 2Q9ZA 3WCAA 4OMGA 1HX9A 2J1PA 4QPFA 2P1CA 5JUZF 1YHKA 5EASA 4KQSA 4H5EF 5AELA 3VJCA 3S9VA 3ICMA 3Q30A 5C05A 2O1OA 4DEMF 2AEKA 4OMHA 4H5CF 1YYUA 4LZ0A 4MC0A 1YHLA 1V4IA 5IKAA 3VJ9A 3KRFB 4Q23A 2F92F 4LOBA 2RAHA 4EA0A 3M0GA 3AQBB 3WCCA 1WKZA 3WCIA 3SDVA 1VG6A 4DWBA 5DJPF 3PH7A 3WCHA 3VJDA 3PYAA 4KVYA 4XQRF 1HXCA 5ILDA 5B0LA 3APZA 3AE0A 2J1OA 4QXSF 4XQSF 4DHDA 2ZCOA 4JVJF 2ZY1A 4GP1A 4NFIF 4UMJA 4KFAA 5ERMA 4MC3A 3OACA 3SDTA 5ILJA 5DW7A 5HN7A 1KIZA 1HM4A 3WE9A 5A0IA 1V4EA 4LFEA 2E4OA 3BNXA 3NF2A 2J5CA 4DZWA 1N1BA 2E8XA 4JXNA 2Q9YA 4LTVA 1V4HA 3CKEA 5EROA 5ERNA 2Z52A 3TFNA 4E9UA 5IMIA 1RQJA 4OKZA 3WEGA 4KUXA 3LOMA 5IVGA 3WCEA 5CG5A 5IM1A 1N23A 1DI1A 3ADZA 3WEFA 1KIYA 5E8KA 4P0VA 4KVWA 4LA5A 3CP6A 3LVSA 2PS8A 2E91A 5IMPA 4LZ3A 2OGDA 3TS7A 4N1ZF 5IK9A 1VG2A 3PDEA 1VG7A 3OYRA 5E8LA 5DGMF 3UCAA 5HN8A 2PS5A 3Q2ZA 5B03A 1UBXA 4K10A 3OABA 5IL3A 3ZL6A 4PVXF 4NFKF 3DYFA 3KRAA 3P5PA 1UBVA 3NPRA 3KRFA 3LZ9A 5A0KA 5DHIA 2ZCSA 3M01A 4F62A 4F6XA 5A0JA 4F6VA 3Q1OA 5EAUA 3NPKA 4DI5A 3N45F 5B01A 3WCBA 2Z4WA 4GA3A 3WCJA 3G4DA 3KB9A 3N49F 3TFPA 1YYQA 4NKEA 3VJEA 5AYPA 3KROB 3DYGA 3SDQA 2E8TA 4LLSA 4KQ5A 4RXDA 3WJKA 3TFVA 5B0MA 2Z7HA 1WMWA 4EA2A 2QISA 5CG6A 2PS7A 4OKMA 2AZLA 3RYEA 2EWGA 3LGKA 2I19A 3KRPB 3ICNA 2ONGA 4KWDA 3LK5A 1YYSA 5ILIA 2F9KF 4XQTF 4KPJA 3ZCDA 3QQVA 4MC8A 3RMGA 3ZMCA 3MAVA 3W7FA 2E8UA 3ASXA 3DYHA 4NKFA 5JV0F 5B0IA 3PKOA 5IKHA 3N1WF 5DZ2A 3KBKA 1VG4A 2DH4A 4NFJF 4OGUA 2OPNA 4RXCA 2Z4VA 3ICKA 4LA6A 1N1ZA 1HXGA 3LJIA 5IK0A 3LGZB 3TC1A 2ZCRA 3ACWA 3EFQA 3IPIA 5DGNF 4P0XA 5I1UA 3M02A 3QKCA 1ZW5A 3WCLA 3V1XA 3SDUA 1PS1A 5IMNA 3M00A 2ONHA 5HN9A 5ILYA 2Q58A 3P41A 1N21A 3N3DA 5E8HA 4N9UA 2ZEUA 3ICZA 3KRCB 4E1EA 1JFGA 2F8CF 3ID0A 2F7MF 3Q2QA
chains in the Genus database with same CATH superfamily
3LDWA 2F89F 5JA0F 5B0JA 1UBWA 1WY0A 4WK5A 1HXAA 3B7LA 4GAXA 4KK2A 3OACB 4ZQ8A 4LZCA 1YJ4A 3AQ0A 4LTZA 1N24A 4GP2A 4KPDA 3WCDA 4RXAA 3KRPA 4KQUA 3VJBA 1RQIA 5DHKA 1N22A 2F8ZF 3S4JA 1YV5A 1RTRA 2OA6A 4LFGA 5IN8A 3LG5A 3MZVA 5EATA 3P5RA 1EZFA 4DWGA 4DXJA 3P8RA 3N6KF 5B02A 2OPMA 3IBAA 1FPSA 3N0FA 3WCMA 5DJRF 5ILZA 1VG3A 3ACXA 4LXWA 3WC9A 5B0KA 1V4KA 3WEHA 1JFAA 1WL2A 2AZKA 4LFVF 2E90A 3N1VF 3SDRA 4P0WA 5IL8A 4KVDA 1WL1A 3EGTA 4KKMA 4KVIA 3RBMA 5HNAA 3LEEA 3M9UA 2Z78A 4NG6A 5DGSF 2E94A 2F94F 3V1VA 3OABB 3WSBA 3KRAB 3WCGA 3N46F 3ZMBA 3LSNA 4LPGF 2Z4ZA 3N5HF 3KRCA 5KSXF 4JZXA 2PS6A 1HM7A 4LLTA 1WL3A 5IK6A 2E8WA 3EZ3A 2H8OA 2E93A 5ER8A 3WEIA 3WJOA 3VJAA 2VF6A 4FJQA 3CC9A 5B00A 3G4FA 2Q80A 5AHUB 3BNYA 3N0GA 5ILKA 4JXYA 4EA1A 1YYTA 2AZJA 3ACYA 2Z4YA 5DJVF 2ZEVA 2AETA 4FP4A 4RNQA 2ZCQA 4L2XF 4H5DF 4RXEA 3PYBA 3LLWA 1YHMA 3V66A 3LMDA 2Z4XA 2FORA 5H9DA 4HD1A 3RYWA 2Z50A 4LUUA 5JV1F 4PVYF 2Z7IA 1YYRA 3WEJA 3AQCB 1WL0A 3KROA 1UBYA 5JV2F 4LPHF 4JZBA 2AELA 2PS4A 1N20A 4RYPA 5DIQF 4NUAA 3SAEA 1V4JA 3WEKA 3N3LF 2E8VA 3WCFA 2E95A 3ZOUA 5ILHA 1YQ7A 3VJ8A 3WSAA 2FTZA 3P8LA 4JYXA 2E92A 3N5JF 1DGPA 4E9ZA 4LIXA 3WJNA 3NRIA 5AFXA 2Q9ZA 3WCAA 4OMGA 1HX9A 2J1PA 4QPFA 2P1CA 5JUZF 1YHKA 5EASA 4KQSA 4H5EF 5AELA 3VJCA 3S9VA 3ICMA 3Q30A 5C05A 2O1OA 4DEMF 2AEKA 4OMHA 4H5CF 1YYUA 4LZ0A 4MC0A 1YHLA 1V4IA 5IKAA 3VJ9A 3KRFB 4Q23A 2F92F 4LOBA 2RAHA 4EA0A 3M0GA 3AQBB 3WCCA 1WKZA 3WCIA 3SDVA 1VG6A 4DWBA 5DJPF 3PH7A 3WCHA 3VJDA 3PYAA 4KVYA 4XQRF 1HXCA 5ILDA 5B0LA 3APZA 3AE0A 2J1OA 4QXSF 4XQSF 4DHDA 2ZCOA 4JVJF 2ZY1A 4GP1A 4NFIF 4UMJA 4KFAA 5ERMA 4MC3A 3OACA 3SDTA 5ILJA 5DW7A 5HN7A 1KIZA 1HM4A 3WE9A 5A0IA 1V4EA 4LFEA 2E4OA 3BNXA 3NF2A 2J5CA 4DZWA 1N1BA 2E8XA 4JXNA 2Q9YA 4LTVA 1V4HA 3CKEA 5EROA 5ERNA 2Z52A 3TFNA 4E9UA 5IMIA 1RQJA 4OKZA 3WEGA 4KUXA 3LOMA 5IVGA 3WCEA 5CG5A 5IM1A 1N23A 1DI1A 3ADZA 3WEFA 1KIYA 5E8KA 4P0VA 4KVWA 4LA5A 3CP6A 3LVSA 2PS8A 2E91A 5IMPA 4LZ3A 2OGDA 3TS7A 4N1ZF 5IK9A 1VG2A 3PDEA 1VG7A 3OYRA 5E8LA 5DGMF 3UCAA 5HN8A 2PS5A 3Q2ZA 5B03A 1UBXA 4K10A 3OABA 5IL3A 3ZL6A 4PVXF 4NFKF 3DYFA 3KRAA 3P5PA 1UBVA 3NPRA 3KRFA 3LZ9A 5A0KA 5DHIA 2ZCSA 3M01A 4F62A 4F6XA 5A0JA 4F6VA 3Q1OA 5EAUA 3NPKA 4DI5A 3N45F 5B01A 3WCBA 2Z4WA 4GA3A 3WCJA 3G4DA 3KB9A 3N49F 3TFPA 1YYQA 4NKEA 3VJEA 5AYPA 3KROB 3DYGA 3SDQA 2E8TA 4LLSA 4KQ5A 4RXDA 3WJKA 3TFVA 5B0MA 2Z7HA 1WMWA 4EA2A 2QISA 5CG6A 2PS7A 4OKMA 2AZLA 3RYEA 2EWGA 3LGKA 2I19A 3KRPB 3ICNA 2ONGA 4KWDA 3LK5A 1YYSA 5ILIA 2F9KF 4XQTF 4KPJA 3ZCDA 3QQVA 4MC8A 3RMGA 3ZMCA 3MAVA 3W7FA 2E8UA 3ASXA 3DYHA 4NKFA 5JV0F 5B0IA 3PKOA 5IKHA 3N1WF 5DZ2A 3KBKA 1VG4A 2DH4A 4NFJF 4OGUA 2OPNA 4RXCA 2Z4VA 3ICKA 4LA6A 1N1ZA 1HXGA 3LJIA 5IK0A 3LGZB 3TC1A 2ZCRA 3ACWA 3EFQA 3IPIA 5DGNF 4P0XA 5I1UA 3M02A 3QKCA 1ZW5A 3WCLA 3V1XA 3SDUA 1PS1A 5IMNA 3M00A 2ONHA 5HN9A 5ILYA 2Q58A 3P41A 1N21A 3N3DA 5E8HA 4N9UA 2ZEUA 3ICZA 3KRCB 4E1EA 1JFGA 2F8CF 3ID0A 2F7MF 3Q2QA
chains in the Genus database with same CATH topology
3LDWA 2F89F 5JA0F 5B0JA 1UBWA 1WY0A 4WK5A 1HXAA 3B7LA 4GAXA 4KK2A 3OACB 4ZQ8A 4LZCA 1YJ4A 3AQ0A 4LTZA 1N24A 4GP2A 4KPDA 3WCDA 4RXAA 3KRPA 4KQUA 3VJBA 1RQIA 5DHKA 1N22A 2F8ZF 3S4JA 1YV5A 1RTRA 2OA6A 4LFGA 5IN8A 3LG5A 3MZVA 5EATA 3P5RA 1EZFA 4DWGA 4DXJA 3P8RA 3N6KF 5B02A 2OPMA 3IBAA 1FPSA 3N0FA 3WCMA 5DJRF 5ILZA 1VG3A 3ACXA 4LXWA 3WC9A 5B0KA 1V4KA 3WEHA 1JFAA 1WL2A 2AZKA 4LFVF 2E90A 3N1VF 3SDRA 4P0WA 5IL8A 4KVDA 1WL1A 3EGTA 4KKMA 4KVIA 3RBMA 5HNAA 3LEEA 3M9UA 2Z78A 4NG6A 5DGSF 2E94A 2F94F 3V1VA 3OABB 3WSBA 3KRAB 3WCGA 3N46F 3ZMBA 3LSNA 4LPGF 2Z4ZA 3N5HF 3KRCA 5KSXF 4JZXA 2PS6A 1HM7A 4LLTA 1WL3A 5IK6A 2E8WA 3EZ3A 2H8OA 2E93A 5ER8A 3WEIA 3WJOA 3VJAA 2VF6A 4FJQA 3CC9A 5B00A 3G4FA 2Q80A 5AHUB 3BNYA 3N0GA 5ILKA 4JXYA 4EA1A 1YYTA 2AZJA 3ACYA 2Z4YA 5DJVF 2ZEVA 2AETA 4FP4A 4RNQA 2ZCQA 4L2XF 4H5DF 4RXEA 3PYBA 3LLWA 1YHMA 3V66A 3LMDA 2Z4XA 2FORA 5H9DA 4HD1A 3RYWA 2Z50A 4LUUA 5JV1F 4PVYF 2Z7IA 1YYRA 3WEJA 3AQCB 1WL0A 3KROA 1UBYA 5JV2F 4LPHF 4JZBA 2AELA 2PS4A 1N20A 4RYPA 5DIQF 4NUAA 3SAEA 1V4JA 3WEKA 3N3LF 2E8VA 3WCFA 2E95A 3ZOUA 5ILHA 1YQ7A 3VJ8A 3WSAA 2FTZA 3P8LA 4JYXA 2E92A 3N5JF 1DGPA 4E9ZA 4LIXA 3WJNA 3NRIA 5AFXA 2Q9ZA 3WCAA 4OMGA 1HX9A 2J1PA 4QPFA 2P1CA 5JUZF 1YHKA 5EASA 4KQSA 4H5EF 5AELA 3VJCA 3S9VA 3ICMA 3Q30A 5C05A 2O1OA 4DEMF 2AEKA 4OMHA 4H5CF 1YYUA 4LZ0A 4MC0A 1YHLA 1V4IA 5IKAA 3VJ9A 3KRFB 4Q23A 2F92F 4LOBA 2RAHA 4EA0A 3M0GA 3AQBB 3WCCA 1WKZA 3WCIA 3SDVA 1VG6A 4DWBA 5DJPF 3PH7A 3WCHA 3VJDA 3PYAA 4KVYA 4XQRF 1HXCA 5ILDA 5B0LA 3APZA 3AE0A 2J1OA 4QXSF 4XQSF 4DHDA 2ZCOA 4JVJF 2ZY1A 4GP1A 4NFIF 4UMJA 4KFAA 5ERMA 4MC3A 3OACA 3SDTA 5ILJA 5DW7A 5HN7A 1KIZA 1HM4A 3WE9A 5A0IA 1V4EA 4LFEA 2E4OA 3BNXA 3NF2A 2J5CA 4DZWA 1N1BA 2E8XA 4JXNA 2Q9YA 4LTVA 1V4HA 3CKEA 5EROA 5ERNA 2Z52A 3TFNA 4E9UA 5IMIA 1RQJA 4OKZA 3WEGA 4KUXA 3LOMA 5IVGA 3WCEA 5CG5A 5IM1A 1N23A 1DI1A 3ADZA 3WEFA 1KIYA 5E8KA 4P0VA 4KVWA 4LA5A 3CP6A 3LVSA 2PS8A 2E91A 5IMPA 4LZ3A 2OGDA 3TS7A 4N1ZF 5IK9A 1VG2A 3PDEA 1VG7A 3OYRA 5E8LA 5DGMF 3UCAA 5HN8A 2PS5A 3Q2ZA 5B03A 1UBXA 4K10A 3OABA 5IL3A 3ZL6A 4PVXF 4NFKF 3DYFA 3KRAA 3P5PA 1UBVA 3NPRA 3KRFA 3LZ9A 5A0KA 5DHIA 2ZCSA 3M01A 4F62A 4F6XA 5A0JA 4F6VA 3Q1OA 5EAUA 3NPKA 4DI5A 3N45F 5B01A 3WCBA 2Z4WA 4GA3A 3WCJA 3G4DA 3KB9A 3N49F 3TFPA 1YYQA 4NKEA 3VJEA 5AYPA 3KROB 3DYGA 3SDQA 2E8TA 4LLSA 4KQ5A 4RXDA 3WJKA 3TFVA 5B0MA 2Z7HA 1WMWA 4EA2A 2QISA 5CG6A 2PS7A 4OKMA 2AZLA 3RYEA 2EWGA 3LGKA 2I19A 3KRPB 3ICNA 2ONGA 4KWDA 3LK5A 1YYSA 5ILIA 2F9KF 4XQTF 4KPJA 3ZCDA 3QQVA 4MC8A 3RMGA 3ZMCA 3MAVA 3W7FA 2E8UA 3ASXA 3DYHA 4NKFA 5JV0F 5B0IA 3PKOA 5IKHA 3N1WF 5DZ2A 3KBKA 1VG4A 2DH4A 4NFJF 4OGUA 2OPNA 4RXCA 2Z4VA 3ICKA 4LA6A 1N1ZA 1HXGA 3LJIA 5IK0A 3LGZB 3TC1A 2ZCRA 3ACWA 3EFQA 3IPIA 5DGNF 4P0XA 5I1UA 3M02A 3QKCA 1ZW5A 3WCLA 3V1XA 3SDUA 1PS1A 5IMNA 3M00A 2ONHA 5HN9A 5ILYA 2Q58A 3P41A 1N21A 3N3DA 5E8HA 4N9UA 2ZEUA 3ICZA 3KRCB 4E1EA 1JFGA 2F8CF 3ID0A 2F7MF 3Q2QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LDW A;  2F89 F;  5JA0 F;  5B0J A;  1UBW A;  1WY0 A;  4WK5 A;  1HXA A;  3B7L A;  4GAX A;  4KK2 A;  3OAC B;  4ZQ8 A;  4LZC A;  1YJ4 A;  3AQ0 A;  4LTZ A;  1N24 A;  4GP2 A;  4KPD A;  3WCD A;  4RXA A;  3KRP A;  4KQU A;  3VJB A;  1RQI A;  5DHK A;  1N22 A;  2F8Z F;  3S4J A;  1YV5 A;  1RTR A;  2OA6 A;  4LFG A;  5IN8 A;  3LG5 A;  3MZV A;  5EAT A;  3P5R A;  1EZF A;  4DWG A;  4DXJ A;  3P8R A;  3N6K F;  5B02 A;  2OPM A;  3IBA A;  1FPS A;  3N0F A;  3WCM A;  5DJR F;  5ILZ A;  1VG3 A;  3ACX A;  4LXW A;  3WC9 A;  5B0K A;  1V4K A;  3WEH A;  1JFA A;  1WL2 A;  2AZK A;  4LFV F;  2E90 A;  3N1V F;  3SDR A;  4P0W A;  5IL8 A;  4KVD A;  1WL1 A;  3EGT A;  4KKM A;  4KVI A;  3RBM A;  5HNA A;  3LEE A;  3M9U A;  2Z78 A;  4NG6 A;  5DGS F;  2E94 A;  2F94 F;  3V1V A;  3OAB B;  3WSB A;  3KRA B;  3WCG A;  3N46 F;  3ZMB A;  3LSN A;  4LPG F;  2Z4Z A;  3N5H F;  3KRC A;  5KSX F;  4JZX A;  2PS6 A;  1HM7 A;  4LLT A;  1WL3 A;  5IK6 A;  2E8W A;  3EZ3 A;  2H8O A;  2E93 A;  5ER8 A;  3WEI A;  3WJO A;  3VJA A;  2VF6 A;  4FJQ A;  3CC9 A;  5B00 A;  3G4F A;  2Q80 A;  5AHU B;  3BNY A;  3N0G A;  5ILK A;  4JXY A;  4EA1 A;  1YYT A;  2AZJ A;  3ACY A;  2Z4Y A;  5DJV F;  2ZEV A;  2AET A;  4FP4 A;  4RNQ A;  2ZCQ A;  4L2X F;  4H5D F;  4RXE A;  3PYB A;  3LLW A;  1YHM A;  3V66 A;  3LMD A;  2Z4X A;  2FOR A;  5H9D A;  4HD1 A;  3RYW A;  2Z50 A;  4LUU A;  5JV1 F;  4PVY F;  2Z7I A;  1YYR A;  3WEJ A;  3AQC B;  1WL0 A;  3KRO A;  1UBY A;  5JV2 F;  4LPH F;  4JZB A;  2AEL A;  2PS4 A;  1N20 A;  4RYP A;  5DIQ F;  4NUA A;  3SAE A;  1V4J A;  3WEK A;  3N3L F;  2E8V A;  3WCF A;  2E95 A;  3ZOU A;  5ILH A;  1YQ7 A;  3VJ8 A;  3WSA A;  2FTZ A;  3P8L A;  4JYX A;  2E92 A;  3N5J F;  1DGP A;  4E9Z A;  4LIX A;  3WJN A;  3NRI A;  5AFX A;  2Q9Z A;  3WCA A;  4OMG A;  1HX9 A;  2J1P A;  4QPF A;  2P1C A;  5JUZ F;  1YHK A;  5EAS A;  4KQS A;  4H5E F;  5AEL A;  3VJC A;  3S9V A;  3ICM A;  3Q30 A;  5C05 A;  2O1O A;  4DEM F;  2AEK A;  4OMH A;  4H5C F;  1YYU A;  4LZ0 A;  4MC0 A;  1YHL A;  1V4I A;  5IKA A;  3VJ9 A;  3KRF B;  4Q23 A;  2F92 F;  4LOB A;  2RAH A;  4EA0 A;  3M0G A;  3AQB B;  3WCC A;  1WKZ A;  3WCI A;  3SDV A;  1VG6 A;  4DWB A;  5DJP F;  3PH7 A;  3WCH A;  3VJD A;  3PYA A;  4KVY A;  4XQR F;  1HXC A;  5ILD A;  5B0L A;  3APZ A;  3AE0 A;  2J1O A;  4QXS F;  4XQS F;  4DHD A;  2ZCO A;  4JVJ F;  2ZY1 A;  4GP1 A;  4NFI F;  4UMJ A;  4KFA A;  5ERM A;  4MC3 A;  3OAC A;  3SDT A;  5ILJ A;  5DW7 A;  5HN7 A;  1KIZ A;  1HM4 A;  3WE9 A;  5A0I A;  1V4E A;  4LFE A;  2E4O A;  3BNX A;  3NF2 A;  2J5C A;  4DZW A;  1N1B A;  2E8X A;  4JXN A;  2Q9Y A;  4LTV A;  1V4H A;  3CKE A;  5ERO A;  5ERN A;  2Z52 A;  3TFN A;  4E9U A;  5IMI A;  1RQJ A;  4OKZ A;  3WEG A;  4KUX A;  3LOM A;  5IVG A;  3WCE A;  5CG5 A;  5IM1 A;  1N23 A;  1DI1 A;  3ADZ A;  3WEF A;  1KIY A;  5E8K A;  4P0V A;  4KVW A;  4LA5 A;  3CP6 A;  3LVS A;  2PS8 A;  2E91 A;  5IMP A;  4LZ3 A;  2OGD A;  3TS7 A;  4N1Z F;  5IK9 A;  1VG2 A;  3PDE A;  1VG7 A;  3OYR A;  5E8L A;  5DGM F;  3UCA A;  5HN8 A;  2PS5 A;  3Q2Z A;  5B03 A;  1UBX A;  4K10 A;  3OAB A;  5IL3 A;  3ZL6 A;  4PVX F;  4NFK F;  3DYF A;  3KRA A;  3P5P A;  1UBV A;  3NPR A;  3KRF A;  3LZ9 A;  5A0K A;  5DHI A;  2ZCS A;  3M01 A;  4F62 A;  4F6X A;  5A0J A;  4F6V A;  3Q1O A;  5EAU A;  3NPK A;  4DI5 A;  3N45 F;  5B01 A;  3WCB A;  2Z4W A;  4GA3 A;  3WCJ A;  3G4D A;  3KB9 A;  3N49 F;  3TFP A;  1YYQ A;  4NKE A;  3VJE A;  5AYP A;  3KRO B;  3DYG A;  3SDQ A;  2E8T A;  4LLS A;  4KQ5 A;  4RXD A;  3WJK A;  3TFV A;  5B0M A;  2Z7H A;  1WMW A;  4EA2 A;  2QIS A;  5CG6 A;  2PS7 A;  4OKM A;  2AZL A;  3RYE A;  2EWG A;  3LGK A;  2I19 A;  3KRP B;  3ICN A;  2ONG A;  4KWD A;  3LK5 A;  1YYS A;  5ILI A;  2F9K F;  4XQT F;  4KPJ A;  3ZCD A;  3QQV A;  4MC8 A;  3RMG A;  3ZMC A;  3MAV A;  3W7F A;  2E8U A;  3ASX A;  3DYH A;  4NKF A;  5JV0 F;  5B0I A;  3PKO A;  5IKH A;  3N1W F;  5DZ2 A;  3KBK A;  1VG4 A;  2DH4 A;  4NFJ F;  4OGU A;  2OPN A;  4RXC A;  2Z4V A;  3ICK A;  4LA6 A;  1N1Z A;  1HXG A;  3LJI A;  5IK0 A;  3LGZ B;  3TC1 A;  2ZCR A;  3ACW A;  3EFQ A;  3IPI A;  5DGN F;  4P0X A;  5I1U A;  3M02 A;  3QKC A;  1ZW5 A;  3WCL A;  3V1X A;  3SDU A;  1PS1 A;  5IMN A;  3M00 A;  2ONH A;  5HN9 A;  5ILY A;  2Q58 A;  3P41 A;  1N21 A;  3N3D A;  5E8H A;  4N9U A;  2ZEU A;  3ICZ A;  3KRC B;  4E1E A;  1JFG A;  2F8C F;  3ID0 A;  2F7M F;  3Q2Q A; 
#chains in the Genus database with same CATH topology
 3LDW A;  2F89 F;  5JA0 F;  5B0J A;  1UBW A;  1WY0 A;  4WK5 A;  1HXA A;  3B7L A;  4GAX A;  4KK2 A;  3OAC B;  4ZQ8 A;  4LZC A;  1YJ4 A;  3AQ0 A;  4LTZ A;  1N24 A;  4GP2 A;  4KPD A;  3WCD A;  4RXA A;  3KRP A;  4KQU A;  3VJB A;  1RQI A;  5DHK A;  1N22 A;  2F8Z F;  3S4J A;  1YV5 A;  1RTR A;  2OA6 A;  4LFG A;  5IN8 A;  3LG5 A;  3MZV A;  5EAT A;  3P5R A;  1EZF A;  4DWG A;  4DXJ A;  3P8R A;  3N6K F;  5B02 A;  2OPM A;  3IBA A;  1FPS A;  3N0F A;  3WCM A;  5DJR F;  5ILZ A;  1VG3 A;  3ACX A;  4LXW A;  3WC9 A;  5B0K A;  1V4K A;  3WEH A;  1JFA A;  1WL2 A;  2AZK A;  4LFV F;  2E90 A;  3N1V F;  3SDR A;  4P0W A;  5IL8 A;  4KVD A;  1WL1 A;  3EGT A;  4KKM A;  4KVI A;  3RBM A;  5HNA A;  3LEE A;  3M9U A;  2Z78 A;  4NG6 A;  5DGS F;  2E94 A;  2F94 F;  3V1V A;  3OAB B;  3WSB A;  3KRA B;  3WCG A;  3N46 F;  3ZMB A;  3LSN A;  4LPG F;  2Z4Z A;  3N5H F;  3KRC A;  5KSX F;  4JZX A;  2PS6 A;  1HM7 A;  4LLT A;  1WL3 A;  5IK6 A;  2E8W A;  3EZ3 A;  2H8O A;  2E93 A;  5ER8 A;  3WEI A;  3WJO A;  3VJA A;  2VF6 A;  4FJQ A;  3CC9 A;  5B00 A;  3G4F A;  2Q80 A;  5AHU B;  3BNY A;  3N0G A;  5ILK A;  4JXY A;  4EA1 A;  1YYT A;  2AZJ A;  3ACY A;  2Z4Y A;  5DJV F;  2ZEV A;  2AET A;  4FP4 A;  4RNQ A;  2ZCQ A;  4L2X F;  4H5D F;  4RXE A;  3PYB A;  3LLW A;  1YHM A;  3V66 A;  3LMD A;  2Z4X A;  2FOR A;  5H9D A;  4HD1 A;  3RYW A;  2Z50 A;  4LUU A;  5JV1 F;  4PVY F;  2Z7I A;  1YYR A;  3WEJ A;  3AQC B;  1WL0 A;  3KRO A;  1UBY A;  5JV2 F;  4LPH F;  4JZB A;  2AEL A;  2PS4 A;  1N20 A;  4RYP A;  5DIQ F;  4NUA A;  3SAE A;  1V4J A;  3WEK A;  3N3L F;  2E8V A;  3WCF A;  2E95 A;  3ZOU A;  5ILH A;  1YQ7 A;  3VJ8 A;  3WSA A;  2FTZ A;  3P8L A;  4JYX A;  2E92 A;  3N5J F;  1DGP A;  4E9Z A;  4LIX A;  3WJN A;  3NRI A;  5AFX A;  2Q9Z A;  3WCA A;  4OMG A;  1HX9 A;  2J1P A;  4QPF A;  2P1C A;  5JUZ F;  1YHK A;  5EAS A;  4KQS A;  4H5E F;  5AEL A;  3VJC A;  3S9V A;  3ICM A;  3Q30 A;  5C05 A;  2O1O A;  4DEM F;  2AEK A;  4OMH A;  4H5C F;  1YYU A;  4LZ0 A;  4MC0 A;  1YHL A;  1V4I A;  5IKA A;  3VJ9 A;  3KRF B;  4Q23 A;  2F92 F;  4LOB A;  2RAH A;  4EA0 A;  3M0G A;  3AQB B;  3WCC A;  1WKZ A;  3WCI A;  3SDV A;  1VG6 A;  4DWB A;  5DJP F;  3PH7 A;  3WCH A;  3VJD A;  3PYA A;  4KVY A;  4XQR F;  1HXC A;  5ILD A;  5B0L A;  3APZ A;  3AE0 A;  2J1O A;  4QXS F;  4XQS F;  4DHD A;  2ZCO A;  4JVJ F;  2ZY1 A;  4GP1 A;  4NFI F;  4UMJ A;  4KFA A;  5ERM A;  4MC3 A;  3OAC A;  3SDT A;  5ILJ A;  5DW7 A;  5HN7 A;  1KIZ A;  1HM4 A;  3WE9 A;  5A0I A;  1V4E A;  4LFE A;  2E4O A;  3BNX A;  3NF2 A;  2J5C A;  4DZW A;  1N1B A;  2E8X A;  4JXN A;  2Q9Y A;  4LTV A;  1V4H A;  3CKE A;  5ERO A;  5ERN A;  2Z52 A;  3TFN A;  4E9U A;  5IMI A;  1RQJ A;  4OKZ A;  3WEG A;  4KUX A;  3LOM A;  5IVG A;  3WCE A;  5CG5 A;  5IM1 A;  1N23 A;  1DI1 A;  3ADZ A;  3WEF A;  1KIY A;  5E8K A;  4P0V A;  4KVW A;  4LA5 A;  3CP6 A;  3LVS A;  2PS8 A;  2E91 A;  5IMP A;  4LZ3 A;  2OGD A;  3TS7 A;  4N1Z F;  5IK9 A;  1VG2 A;  3PDE A;  1VG7 A;  3OYR A;  5E8L A;  5DGM F;  3UCA A;  5HN8 A;  2PS5 A;  3Q2Z A;  5B03 A;  1UBX A;  4K10 A;  3OAB A;  5IL3 A;  3ZL6 A;  4PVX F;  4NFK F;  3DYF A;  3KRA A;  3P5P A;  1UBV A;  3NPR A;  3KRF A;  3LZ9 A;  5A0K A;  5DHI A;  2ZCS A;  3M01 A;  4F62 A;  4F6X A;  5A0J A;  4F6V A;  3Q1O A;  5EAU A;  3NPK A;  4DI5 A;  3N45 F;  5B01 A;  3WCB A;  2Z4W A;  4GA3 A;  3WCJ A;  3G4D A;  3KB9 A;  3N49 F;  3TFP A;  1YYQ A;  4NKE A;  3VJE A;  5AYP A;  3KRO B;  3DYG A;  3SDQ A;  2E8T A;  4LLS A;  4KQ5 A;  4RXD A;  3WJK A;  3TFV A;  5B0M A;  2Z7H A;  1WMW A;  4EA2 A;  2QIS A;  5CG6 A;  2PS7 A;  4OKM A;  2AZL A;  3RYE A;  2EWG A;  3LGK A;  2I19 A;  3KRP B;  3ICN A;  2ONG A;  4KWD A;  3LK5 A;  1YYS A;  5ILI A;  2F9K F;  4XQT F;  4KPJ A;  3ZCD A;  3QQV A;  4MC8 A;  3RMG A;  3ZMC A;  3MAV A;  3W7F A;  2E8U A;  3ASX A;  3DYH A;  4NKF A;  5JV0 F;  5B0I A;  3PKO A;  5IKH A;  3N1W F;  5DZ2 A;  3KBK A;  1VG4 A;  2DH4 A;  4NFJ F;  4OGU A;  2OPN A;  4RXC A;  2Z4V A;  3ICK A;  4LA6 A;  1N1Z A;  1HXG A;  3LJI A;  5IK0 A;  3LGZ B;  3TC1 A;  2ZCR A;  3ACW A;  3EFQ A;  3IPI A;  5DGN F;  4P0X A;  5I1U A;  3M02 A;  3QKC A;  1ZW5 A;  3WCL A;  3V1X A;  3SDU A;  1PS1 A;  5IMN A;  3M00 A;  2ONH A;  5HN9 A;  5ILY A;  2Q58 A;  3P41 A;  1N21 A;  3N3D A;  5E8H A;  4N9U A;  2ZEU A;  3ICZ A;  3KRC B;  4E1E A;  1JFG A;  2F8C F;  3ID0 A;  2F7M F;  3Q2Q A; 
#chains in the Genus database with same CATH homology
 3LDW A;  2F89 F;  5JA0 F;  5B0J A;  1UBW A;  1WY0 A;  4WK5 A;  1HXA A;  3B7L A;  4GAX A;  4KK2 A;  3OAC B;  4ZQ8 A;  4LZC A;  1YJ4 A;  3AQ0 A;  4LTZ A;  1N24 A;  4GP2 A;  4KPD A;  3WCD A;  4RXA A;  3KRP A;  4KQU A;  3VJB A;  1RQI A;  5DHK A;  1N22 A;  2F8Z F;  3S4J A;  1YV5 A;  1RTR A;  2OA6 A;  4LFG A;  5IN8 A;  3LG5 A;  3MZV A;  5EAT A;  3P5R A;  1EZF A;  4DWG A;  4DXJ A;  3P8R A;  3N6K F;  5B02 A;  2OPM A;  3IBA A;  1FPS A;  3N0F A;  3WCM A;  5DJR F;  5ILZ A;  1VG3 A;  3ACX A;  4LXW A;  3WC9 A;  5B0K A;  1V4K A;  3WEH A;  1JFA A;  1WL2 A;  2AZK A;  4LFV F;  2E90 A;  3N1V F;  3SDR A;  4P0W A;  5IL8 A;  4KVD A;  1WL1 A;  3EGT A;  4KKM A;  4KVI A;  3RBM A;  5HNA A;  3LEE A;  3M9U A;  2Z78 A;  4NG6 A;  5DGS F;  2E94 A;  2F94 F;  3V1V A;  3OAB B;  3WSB A;  3KRA B;  3WCG A;  3N46 F;  3ZMB A;  3LSN A;  4LPG F;  2Z4Z A;  3N5H F;  3KRC A;  5KSX F;  4JZX A;  2PS6 A;  1HM7 A;  4LLT A;  1WL3 A;  5IK6 A;  2E8W A;  3EZ3 A;  2H8O A;  2E93 A;  5ER8 A;  3WEI A;  3WJO A;  3VJA A;  2VF6 A;  4FJQ A;  3CC9 A;  5B00 A;  3G4F A;  2Q80 A;  5AHU B;  3BNY A;  3N0G A;  5ILK A;  4JXY A;  4EA1 A;  1YYT A;  2AZJ A;  3ACY A;  2Z4Y A;  5DJV F;  2ZEV A;  2AET A;  4FP4 A;  4RNQ A;  2ZCQ A;  4L2X F;  4H5D F;  4RXE A;  3PYB A;  3LLW A;  1YHM A;  3V66 A;  3LMD A;  2Z4X A;  2FOR A;  5H9D A;  4HD1 A;  3RYW A;  2Z50 A;  4LUU A;  5JV1 F;  4PVY F;  2Z7I A;  1YYR A;  3WEJ A;  3AQC B;  1WL0 A;  3KRO A;  1UBY A;  5JV2 F;  4LPH F;  4JZB A;  2AEL A;  2PS4 A;  1N20 A;  4RYP A;  5DIQ F;  4NUA A;  3SAE A;  1V4J A;  3WEK A;  3N3L F;  2E8V A;  3WCF A;  2E95 A;  3ZOU A;  5ILH A;  1YQ7 A;  3VJ8 A;  3WSA A;  2FTZ A;  3P8L A;  4JYX A;  2E92 A;  3N5J F;  1DGP A;  4E9Z A;  4LIX A;  3WJN A;  3NRI A;  5AFX A;  2Q9Z A;  3WCA A;  4OMG A;  1HX9 A;  2J1P A;  4QPF A;  2P1C A;  5JUZ F;  1YHK A;  5EAS A;  4KQS A;  4H5E F;  5AEL A;  3VJC A;  3S9V A;  3ICM A;  3Q30 A;  5C05 A;  2O1O A;  4DEM F;  2AEK A;  4OMH A;  4H5C F;  1YYU A;  4LZ0 A;  4MC0 A;  1YHL A;  1V4I A;  5IKA A;  3VJ9 A;  3KRF B;  4Q23 A;  2F92 F;  4LOB A;  2RAH A;  4EA0 A;  3M0G A;  3AQB B;  3WCC A;  1WKZ A;  3WCI A;  3SDV A;  1VG6 A;  4DWB A;  5DJP F;  3PH7 A;  3WCH A;  3VJD A;  3PYA A;  4KVY A;  4XQR F;  1HXC A;  5ILD A;  5B0L A;  3APZ A;  3AE0 A;  2J1O A;  4QXS F;  4XQS F;  4DHD A;  2ZCO A;  4JVJ F;  2ZY1 A;  4GP1 A;  4NFI F;  4UMJ A;  4KFA A;  5ERM A;  4MC3 A;  3OAC A;  3SDT A;  5ILJ A;  5DW7 A;  5HN7 A;  1KIZ A;  1HM4 A;  3WE9 A;  5A0I A;  1V4E A;  4LFE A;  2E4O A;  3BNX A;  3NF2 A;  2J5C A;  4DZW A;  1N1B A;  2E8X A;  4JXN A;  2Q9Y A;  4LTV A;  1V4H A;  3CKE A;  5ERO A;  5ERN A;  2Z52 A;  3TFN A;  4E9U A;  5IMI A;  1RQJ A;  4OKZ A;  3WEG A;  4KUX A;  3LOM A;  5IVG A;  3WCE A;  5CG5 A;  5IM1 A;  1N23 A;  1DI1 A;  3ADZ A;  3WEF A;  1KIY A;  5E8K A;  4P0V A;  4KVW A;  4LA5 A;  3CP6 A;  3LVS A;  2PS8 A;  2E91 A;  5IMP A;  4LZ3 A;  2OGD A;  3TS7 A;  4N1Z F;  5IK9 A;  1VG2 A;  3PDE A;  1VG7 A;  3OYR A;  5E8L A;  5DGM F;  3UCA A;  5HN8 A;  2PS5 A;  3Q2Z A;  5B03 A;  1UBX A;  4K10 A;  3OAB A;  5IL3 A;  3ZL6 A;  4PVX F;  4NFK F;  3DYF A;  3KRA A;  3P5P A;  1UBV A;  3NPR A;  3KRF A;  3LZ9 A;  5A0K A;  5DHI A;  2ZCS A;  3M01 A;  4F62 A;  4F6X A;  5A0J A;  4F6V A;  3Q1O A;  5EAU A;  3NPK A;  4DI5 A;  3N45 F;  5B01 A;  3WCB A;  2Z4W A;  4GA3 A;  3WCJ A;  3G4D A;  3KB9 A;  3N49 F;  3TFP A;  1YYQ A;  4NKE A;  3VJE A;  5AYP A;  3KRO B;  3DYG A;  3SDQ A;  2E8T A;  4LLS A;  4KQ5 A;  4RXD A;  3WJK A;  3TFV A;  5B0M A;  2Z7H A;  1WMW A;  4EA2 A;  2QIS A;  5CG6 A;  2PS7 A;  4OKM A;  2AZL A;  3RYE A;  2EWG A;  3LGK A;  2I19 A;  3KRP B;  3ICN A;  2ONG A;  4KWD A;  3LK5 A;  1YYS A;  5ILI A;  2F9K F;  4XQT F;  4KPJ A;  3ZCD A;  3QQV A;  4MC8 A;  3RMG A;  3ZMC A;  3MAV A;  3W7F A;  2E8U A;  3ASX A;  3DYH A;  4NKF A;  5JV0 F;  5B0I A;  3PKO A;  5IKH A;  3N1W F;  5DZ2 A;  3KBK A;  1VG4 A;  2DH4 A;  4NFJ F;  4OGU A;  2OPN A;  4RXC A;  2Z4V A;  3ICK A;  4LA6 A;  1N1Z A;  1HXG A;  3LJI A;  5IK0 A;  3LGZ B;  3TC1 A;  2ZCR A;  3ACW A;  3EFQ A;  3IPI A;  5DGN F;  4P0X A;  5I1U A;  3M02 A;  3QKC A;  1ZW5 A;  3WCL A;  3V1X A;  3SDU A;  1PS1 A;  5IMN A;  3M00 A;  2ONH A;  5HN9 A;  5ILY A;  2Q58 A;  3P41 A;  1N21 A;  3N3D A;  5E8H A;  4N9U A;  2ZEU A;  3ICZ A;  3KRC B;  4E1E A;  1JFG A;  2F8C F;  3ID0 A;  2F7M F;  3Q2Q A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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