1YHKA

Trypanosoma cruzi farnesyl diphosphate synthase
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
360
structure length
360
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: Implications for drug design.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords farnesyl pyrophosphate synthase
total genus 147
structure length 360
sequence length 360
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2005-01-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 1yhkA00
1FPSA 3WEHA 5HN8A 3UCAA 2F7MF 5ILIA 3G4FA 5I1UA 3P8LA 2Q80A 1YYRA 2E8TA 3LVSA 3WJKA 2E93A 3CC9A 3WCIA 3OABB 5B03A 3AQ0A 3LJIA 2OA6A 5IM1A 2Z52A 1YHMA 4KQSA 5AHUB 3WSBA 1YHLA 4DWGA 4LFVF 3WCEA 1KIZA 3V1VA 4F6VA 5EROA 3VJEA 4LFEA 5DGMF 3KRPA 4LLSA 3WC9A 2F94F 4KVDA 4JVJF 4LZ3A 3RYEA 4KWDA 3Q1OA 3ZCDA 3Q2ZA 4DEMF 4OMHA 4H5DF 4JXNA 4LZCA 3WEGA 3N3DA 2AZLA 3EZ3A 1WY0A 4XQSF 3TS7A 1WL0A 1N23A 3PYBA 3VJ8A 2FTZA 5EAUA 5ERNA 4MC0A 5B0JA 4E9UA 5IKHA 5H9DA 1VG7A 2Q58A 3AE0A 1YYUA 4KUXA 4OMGA 4KQ5A 2F92F 2QISA 3N45F 3TFPA 4KVIA 3WEJA 4P0XA 1RTRA 2Z4VA 3WCLA 1WMWA 5JA0F 2Z4WA 3IPIA 3LOMA 5IK0A 3KROB 3M00A 4JZXA 2E90A 1WKZA 5IMNA 4RNQA 3P8RA 3SDUA 4GA3A 4RXCA 3G4DA 1YHKA 3M01A 1N20A 2F89F 4E1EA 4NUAA 3VJAA 5A0KA 5C05A 4LA5A 5B0LA 5DJPF 2EWGA 2ZY1A 5B00A 4PVYF 4KFAA 4NG6A 3PKOA 4F6XA 3QQVA 4PVXF 4EA0A 5A0JA 4LOBA 2DH4A 3WCFA 4RXDA 2OPNA 4FP4A 3Q30A 3AQBB 1VG2A 3WCJA 1PS1A 4MC8A 3EGTA 1HXAA 2I19A 3OACB 3W7FA 3WE9A 4F62A 3ACYA 5JV2F 1DGPA 4RXAA 2AELA 4NFKF 3WCMA 4LXWA 5IKAA 4KPJA 3P41A 3M0GA 1V4KA 4DXJA 1V4HA 2AZJA 4P0VA 3TC1A 4KK2A 1UBVA 1VG4A 4QPFA 1UBYA 2AETA 3LGZB 2Z50A 1V4JA 3AQCB 2ZCRA 3LK5A 5ILHA 3ASXA 1JFAA 1N22A 3N6KF 1ZW5A 3VJDA 2P1CA 3WSAA 3ACWA 3S9VA 1HX9A 2O1OA 4RYPA 1YV5A 5HN7A 1WL3A 5DHIA 3WJOA 3NF2A 2VF6A 4EA1A 3M9UA 4XQTF 3KRPB 1UBXA 4LPGF 5E8HA 5ER8A 3PDEA 5ILKA 5EATA 2F9KF 2ONHA 3ZL6A 3WEIA 2Z78A 4QXSF 3N1WF 1YYSA 4E9ZA 1EZFA 2PS8A 2PS6A 2J5CA 3ID0A 1HXCA 3LGKA 2E8XA 5AYPA 3N0GA 1HM4A 1HXGA 3VJBA 5AELA 4L2XF 5HN9A 5B0IA 4DWBA 3ICZA 3TFNA 3CKEA 5ILJA 1YJ4A 4LTZA 5DHKA 3RYWA 3N3LF 1WL1A 2PS5A 3NPKA 4LLTA 3DYFA 4DZWA 4LUUA 3Q2QA 2ONGA 4FJQA 3WCHA 1RQIA 4JXYA 4HD1A 2E95A 4GP2A 3SDTA 1YQ7A 3KB9A 3CP6A 4P0WA 1YYQA 3WCAA 5B0KA 3EFQA 1JFGA 1V4IA 2Z4ZA 1DI1A 2E94A 4NKFA 1N1ZA 3WCDA 5IL8A 3WEFA 2ZCOA 4NKEA 3NPRA 3KRFA 1KIYA 3SDQA 3LLWA 3M02A 3V1XA 5B02A 2J1OA 5AFXA 2Z4XA 3WCGA 4JYXA 5JV0F 3LSNA 4OKMA 2PS7A 3ZOUA 2Z7HA 2RAHA 4KPDA 3KRAA 3MAVA 3LZ9A 5DZ2A 1V4EA 4KKMA 3APZA 3LDWA 3OABA 3P5PA 2Q9ZA 5IL3A 3LEEA 4DHDA 2ZEVA 3OYRA 4H5CF 4NFIF 3IBAA 5KSXF 1N21A 2E92A 3KRAB 4MC3A 3SAEA 4XQRF 2F8ZF 5CG5A 3PYAA 4WK5A 3ACXA 5IMPA 3VJ9A 3N49F 5IK6A 3WCCA 4Q23A 3KRCA 3N46F 2Q9YA 1WL2A 1RQJA 5ERMA 5EASA 3PH7A 2OGDA 5A0IA 3TFVA 2E4OA 3SDRA 5B01A 5IMIA 3P5RA 5IN8A 5JV1F 4LPHF 5DGNF 3S4JA 4RXEA 3KRCB 4GP1A 1N24A 4OGUA 3MZVA 3KBKA 2E91A 3DYGA 4NFJF 2F8CF 2E8UA 2E8VA 2ZCQA 5IVGA 5B0MA 3SDVA 4DI5A 5JUZF 3N5HF 3ADZA 4LIXA 2H8OA 5ILZA 4UMJA 1UBWA 3LG5A 4JZBA 4ZQ8A 3BNXA 3KROA 5DJRF 3QKCA 2ZEUA 4K10A 2ZCSA 2AZKA 5CG6A 3ZMCA 3WJNA 1VG3A 3N0FA 2OPMA 3N1VF 2AEKA 3NRIA 4GAXA 4OKZA 3V66A 1YYTA 4LTVA 4KVYA 2Z7IA 3B7LA 2J1PA 5IK9A 3ICMA 4N9UA 4H5EF 4KVWA 3VJCA 3WEKA 3LMDA 4N1ZF 3DYHA 5DIQF 4LA6A 3WCBA 3N5JF 5E8KA 4EA2A 5ILYA 2PS4A 5E8LA 4LFGA 3ICKA 3BNYA 5HNAA 2E8WA 1HM7A 3RBMA 3KRFB 1VG6A 5ILDA 4KQUA 3RMGA 5DW7A 3ZMBA 5DGSF 3ICNA 3OACA 2Z4YA 2FORA 5DJVF 1N1BA 4LZ0A
chains in the Genus database with same CATH superfamily
1FPSA 3WEHA 5HN8A 3UCAA 2F7MF 5ILIA 3G4FA 5I1UA 3P8LA 2Q80A 1YYRA 2E8TA 3LVSA 3WJKA 2E93A 3CC9A 3WCIA 3OABB 5B03A 3AQ0A 3LJIA 2OA6A 5IM1A 2Z52A 1YHMA 4KQSA 5AHUB 3WSBA 1YHLA 4DWGA 4LFVF 3WCEA 1KIZA 3V1VA 4F6VA 5EROA 3VJEA 4LFEA 5DGMF 3KRPA 4LLSA 3WC9A 2F94F 4KVDA 4JVJF 4LZ3A 3RYEA 4KWDA 3Q1OA 3ZCDA 3Q2ZA 4DEMF 4OMHA 4H5DF 4JXNA 4LZCA 3WEGA 3N3DA 2AZLA 3EZ3A 1WY0A 4XQSF 3TS7A 1WL0A 1N23A 3PYBA 3VJ8A 2FTZA 5EAUA 5ERNA 4MC0A 5B0JA 4E9UA 5IKHA 5H9DA 1VG7A 2Q58A 3AE0A 1YYUA 4KUXA 4OMGA 4KQ5A 2F92F 2QISA 3N45F 3TFPA 4KVIA 3WEJA 4P0XA 1RTRA 2Z4VA 3WCLA 1WMWA 5JA0F 2Z4WA 3IPIA 3LOMA 5IK0A 3KROB 3M00A 4JZXA 2E90A 1WKZA 5IMNA 4RNQA 3P8RA 3SDUA 4GA3A 4RXCA 3G4DA 1YHKA 3M01A 1N20A 2F89F 4E1EA 4NUAA 3VJAA 5A0KA 5C05A 4LA5A 5B0LA 5DJPF 2EWGA 2ZY1A 5B00A 4PVYF 4KFAA 4NG6A 3PKOA 4F6XA 3QQVA 4PVXF 4EA0A 5A0JA 4LOBA 2DH4A 3WCFA 4RXDA 2OPNA 4FP4A 3Q30A 3AQBB 1VG2A 3WCJA 1PS1A 4MC8A 3EGTA 1HXAA 2I19A 3OACB 3W7FA 3WE9A 4F62A 3ACYA 5JV2F 1DGPA 4RXAA 2AELA 4NFKF 3WCMA 4LXWA 5IKAA 4KPJA 3P41A 3M0GA 1V4KA 4DXJA 1V4HA 2AZJA 4P0VA 3TC1A 4KK2A 1UBVA 1VG4A 4QPFA 1UBYA 2AETA 3LGZB 2Z50A 1V4JA 3AQCB 2ZCRA 3LK5A 5ILHA 3ASXA 1JFAA 1N22A 3N6KF 1ZW5A 3VJDA 2P1CA 3WSAA 3ACWA 3S9VA 1HX9A 2O1OA 4RYPA 1YV5A 5HN7A 1WL3A 5DHIA 3WJOA 3NF2A 2VF6A 4EA1A 3M9UA 4XQTF 3KRPB 1UBXA 4LPGF 5E8HA 5ER8A 3PDEA 5ILKA 5EATA 2F9KF 2ONHA 3ZL6A 3WEIA 2Z78A 4QXSF 3N1WF 1YYSA 4E9ZA 1EZFA 2PS8A 2PS6A 2J5CA 3ID0A 1HXCA 3LGKA 2E8XA 5AYPA 3N0GA 1HM4A 1HXGA 3VJBA 5AELA 4L2XF 5HN9A 5B0IA 4DWBA 3ICZA 3TFNA 3CKEA 5ILJA 1YJ4A 4LTZA 5DHKA 3RYWA 3N3LF 1WL1A 2PS5A 3NPKA 4LLTA 3DYFA 4DZWA 4LUUA 3Q2QA 2ONGA 4FJQA 3WCHA 1RQIA 4JXYA 4HD1A 2E95A 4GP2A 3SDTA 1YQ7A 3KB9A 3CP6A 4P0WA 1YYQA 3WCAA 5B0KA 3EFQA 1JFGA 1V4IA 2Z4ZA 1DI1A 2E94A 4NKFA 1N1ZA 3WCDA 5IL8A 3WEFA 2ZCOA 4NKEA 3NPRA 3KRFA 1KIYA 3SDQA 3LLWA 3M02A 3V1XA 5B02A 2J1OA 5AFXA 2Z4XA 3WCGA 4JYXA 5JV0F 3LSNA 4OKMA 2PS7A 3ZOUA 2Z7HA 2RAHA 4KPDA 3KRAA 3MAVA 3LZ9A 5DZ2A 1V4EA 4KKMA 3APZA 3LDWA 3OABA 3P5PA 2Q9ZA 5IL3A 3LEEA 4DHDA 2ZEVA 3OYRA 4H5CF 4NFIF 3IBAA 5KSXF 1N21A 2E92A 3KRAB 4MC3A 3SAEA 4XQRF 2F8ZF 5CG5A 3PYAA 4WK5A 3ACXA 5IMPA 3VJ9A 3N49F 5IK6A 3WCCA 4Q23A 3KRCA 3N46F 2Q9YA 1WL2A 1RQJA 5ERMA 5EASA 3PH7A 2OGDA 5A0IA 3TFVA 2E4OA 3SDRA 5B01A 5IMIA 3P5RA 5IN8A 5JV1F 4LPHF 5DGNF 3S4JA 4RXEA 3KRCB 4GP1A 1N24A 4OGUA 3MZVA 3KBKA 2E91A 3DYGA 4NFJF 2F8CF 2E8UA 2E8VA 2ZCQA 5IVGA 5B0MA 3SDVA 4DI5A 5JUZF 3N5HF 3ADZA 4LIXA 2H8OA 5ILZA 4UMJA 1UBWA 3LG5A 4JZBA 4ZQ8A 3BNXA 3KROA 5DJRF 3QKCA 2ZEUA 4K10A 2ZCSA 2AZKA 5CG6A 3ZMCA 3WJNA 1VG3A 3N0FA 2OPMA 3N1VF 2AEKA 3NRIA 4GAXA 4OKZA 3V66A 1YYTA 4LTVA 4KVYA 2Z7IA 3B7LA 2J1PA 5IK9A 3ICMA 4N9UA 4H5EF 4KVWA 3VJCA 3WEKA 3LMDA 4N1ZF 3DYHA 5DIQF 4LA6A 3WCBA 3N5JF 5E8KA 4EA2A 5ILYA 2PS4A 5E8LA 4LFGA 3ICKA 3BNYA 5HNAA 2E8WA 1HM7A 3RBMA 3KRFB 1VG6A 5ILDA 4KQUA 3RMGA 5DW7A 3ZMBA 5DGSF 3ICNA 3OACA 2Z4YA 2FORA 5DJVF 1N1BA 4LZ0A
chains in the Genus database with same CATH topology
1FPSA 3WEHA 5HN8A 3UCAA 2F7MF 5ILIA 3G4FA 5I1UA 3P8LA 2Q80A 1YYRA 2E8TA 3LVSA 3WJKA 2E93A 3CC9A 3WCIA 3OABB 5B03A 3AQ0A 3LJIA 2OA6A 5IM1A 2Z52A 1YHMA 4KQSA 5AHUB 3WSBA 1YHLA 4DWGA 4LFVF 3WCEA 1KIZA 3V1VA 4F6VA 5EROA 3VJEA 4LFEA 5DGMF 3KRPA 4LLSA 3WC9A 2F94F 4KVDA 4JVJF 4LZ3A 3RYEA 4KWDA 3Q1OA 3ZCDA 3Q2ZA 4DEMF 4OMHA 4H5DF 4JXNA 4LZCA 3WEGA 3N3DA 2AZLA 3EZ3A 1WY0A 4XQSF 3TS7A 1WL0A 1N23A 3PYBA 3VJ8A 2FTZA 5EAUA 5ERNA 4MC0A 5B0JA 4E9UA 5IKHA 5H9DA 1VG7A 2Q58A 3AE0A 1YYUA 4KUXA 4OMGA 4KQ5A 2F92F 2QISA 3N45F 3TFPA 4KVIA 3WEJA 4P0XA 1RTRA 2Z4VA 3WCLA 1WMWA 5JA0F 2Z4WA 3IPIA 3LOMA 5IK0A 3KROB 3M00A 4JZXA 2E90A 1WKZA 5IMNA 4RNQA 3P8RA 3SDUA 4GA3A 4RXCA 3G4DA 1YHKA 3M01A 1N20A 2F89F 4E1EA 4NUAA 3VJAA 5A0KA 5C05A 4LA5A 5B0LA 5DJPF 2EWGA 2ZY1A 5B00A 4PVYF 4KFAA 4NG6A 3PKOA 4F6XA 3QQVA 4PVXF 4EA0A 5A0JA 4LOBA 2DH4A 3WCFA 4RXDA 2OPNA 4FP4A 3Q30A 3AQBB 1VG2A 3WCJA 1PS1A 4MC8A 3EGTA 1HXAA 2I19A 3OACB 3W7FA 3WE9A 4F62A 3ACYA 5JV2F 1DGPA 4RXAA 2AELA 4NFKF 3WCMA 4LXWA 5IKAA 4KPJA 3P41A 3M0GA 1V4KA 4DXJA 1V4HA 2AZJA 4P0VA 3TC1A 4KK2A 1UBVA 1VG4A 4QPFA 1UBYA 2AETA 3LGZB 2Z50A 1V4JA 3AQCB 2ZCRA 3LK5A 5ILHA 3ASXA 1JFAA 1N22A 3N6KF 1ZW5A 3VJDA 2P1CA 3WSAA 3ACWA 3S9VA 1HX9A 2O1OA 4RYPA 1YV5A 5HN7A 1WL3A 5DHIA 3WJOA 3NF2A 2VF6A 4EA1A 3M9UA 4XQTF 3KRPB 1UBXA 4LPGF 5E8HA 5ER8A 3PDEA 5ILKA 5EATA 2F9KF 2ONHA 3ZL6A 3WEIA 2Z78A 4QXSF 3N1WF 1YYSA 4E9ZA 1EZFA 2PS8A 2PS6A 2J5CA 3ID0A 1HXCA 3LGKA 2E8XA 5AYPA 3N0GA 1HM4A 1HXGA 3VJBA 5AELA 4L2XF 5HN9A 5B0IA 4DWBA 3ICZA 3TFNA 3CKEA 5ILJA 1YJ4A 4LTZA 5DHKA 3RYWA 3N3LF 1WL1A 2PS5A 3NPKA 4LLTA 3DYFA 4DZWA 4LUUA 3Q2QA 2ONGA 4FJQA 3WCHA 1RQIA 4JXYA 4HD1A 2E95A 4GP2A 3SDTA 1YQ7A 3KB9A 3CP6A 4P0WA 1YYQA 3WCAA 5B0KA 3EFQA 1JFGA 1V4IA 2Z4ZA 1DI1A 2E94A 4NKFA 1N1ZA 3WCDA 5IL8A 3WEFA 2ZCOA 4NKEA 3NPRA 3KRFA 1KIYA 3SDQA 3LLWA 3M02A 3V1XA 5B02A 2J1OA 5AFXA 2Z4XA 3WCGA 4JYXA 5JV0F 3LSNA 4OKMA 2PS7A 3ZOUA 2Z7HA 2RAHA 4KPDA 3KRAA 3MAVA 3LZ9A 5DZ2A 1V4EA 4KKMA 3APZA 3LDWA 3OABA 3P5PA 2Q9ZA 5IL3A 3LEEA 4DHDA 2ZEVA 3OYRA 4H5CF 4NFIF 3IBAA 5KSXF 1N21A 2E92A 3KRAB 4MC3A 3SAEA 4XQRF 2F8ZF 5CG5A 3PYAA 4WK5A 3ACXA 5IMPA 3VJ9A 3N49F 5IK6A 3WCCA 4Q23A 3KRCA 3N46F 2Q9YA 1WL2A 1RQJA 5ERMA 5EASA 3PH7A 2OGDA 5A0IA 3TFVA 2E4OA 3SDRA 5B01A 5IMIA 3P5RA 5IN8A 5JV1F 4LPHF 5DGNF 3S4JA 4RXEA 3KRCB 4GP1A 1N24A 4OGUA 3MZVA 3KBKA 2E91A 3DYGA 4NFJF 2F8CF 2E8UA 2E8VA 2ZCQA 5IVGA 5B0MA 3SDVA 4DI5A 5JUZF 3N5HF 3ADZA 4LIXA 2H8OA 5ILZA 4UMJA 1UBWA 3LG5A 4JZBA 4ZQ8A 3BNXA 3KROA 5DJRF 3QKCA 2ZEUA 4K10A 2ZCSA 2AZKA 5CG6A 3ZMCA 3WJNA 1VG3A 3N0FA 2OPMA 3N1VF 2AEKA 3NRIA 4GAXA 4OKZA 3V66A 1YYTA 4LTVA 4KVYA 2Z7IA 3B7LA 2J1PA 5IK9A 3ICMA 4N9UA 4H5EF 4KVWA 3VJCA 3WEKA 3LMDA 4N1ZF 3DYHA 5DIQF 4LA6A 3WCBA 3N5JF 5E8KA 4EA2A 5ILYA 2PS4A 5E8LA 4LFGA 3ICKA 3BNYA 5HNAA 2E8WA 1HM7A 3RBMA 3KRFB 1VG6A 5ILDA 4KQUA 3RMGA 5DW7A 3ZMBA 5DGSF 3ICNA 3OACA 2Z4YA 2FORA 5DJVF 1N1BA 4LZ0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FPS A;  3WEH A;  5HN8 A;  3UCA A;  2F7M F;  5ILI A;  3G4F A;  5I1U A;  3P8L A;  2Q80 A;  1YYR A;  2E8T A;  3LVS A;  3WJK A;  2E93 A;  3CC9 A;  3WCI A;  3OAB B;  5B03 A;  3AQ0 A;  3LJI A;  2OA6 A;  5IM1 A;  2Z52 A;  1YHM A;  4KQS A;  5AHU B;  3WSB A;  1YHL A;  4DWG A;  4LFV F;  3WCE A;  1KIZ A;  3V1V A;  4F6V A;  5ERO A;  3VJE A;  4LFE A;  5DGM F;  3KRP A;  4LLS A;  3WC9 A;  2F94 F;  4KVD A;  4JVJ F;  4LZ3 A;  3RYE A;  4KWD A;  3Q1O A;  3ZCD A;  3Q2Z A;  4DEM F;  4OMH A;  4H5D F;  4JXN A;  4LZC A;  3WEG A;  3N3D A;  2AZL A;  3EZ3 A;  1WY0 A;  4XQS F;  3TS7 A;  1WL0 A;  1N23 A;  3PYB A;  3VJ8 A;  2FTZ A;  5EAU A;  5ERN A;  4MC0 A;  5B0J A;  4E9U A;  5IKH A;  5H9D A;  1VG7 A;  2Q58 A;  3AE0 A;  1YYU A;  4KUX A;  4OMG A;  4KQ5 A;  2F92 F;  2QIS A;  3N45 F;  3TFP A;  4KVI A;  3WEJ A;  4P0X A;  1RTR A;  2Z4V A;  3WCL A;  1WMW A;  5JA0 F;  2Z4W A;  3IPI A;  3LOM A;  5IK0 A;  3KRO B;  3M00 A;  4JZX A;  2E90 A;  1WKZ A;  5IMN A;  4RNQ A;  3P8R A;  3SDU A;  4GA3 A;  4RXC A;  3G4D A;  1YHK A;  3M01 A;  1N20 A;  2F89 F;  4E1E A;  4NUA A;  3VJA A;  5A0K A;  5C05 A;  4LA5 A;  5B0L A;  5DJP F;  2EWG A;  2ZY1 A;  5B00 A;  4PVY F;  4KFA A;  4NG6 A;  3PKO A;  4F6X A;  3QQV A;  4PVX F;  4EA0 A;  5A0J A;  4LOB A;  2DH4 A;  3WCF A;  4RXD A;  2OPN A;  4FP4 A;  3Q30 A;  3AQB B;  1VG2 A;  3WCJ A;  1PS1 A;  4MC8 A;  3EGT A;  1HXA A;  2I19 A;  3OAC B;  3W7F A;  3WE9 A;  4F62 A;  3ACY A;  5JV2 F;  1DGP A;  4RXA A;  2AEL A;  4NFK F;  3WCM A;  4LXW A;  5IKA A;  4KPJ A;  3P41 A;  3M0G A;  1V4K A;  4DXJ A;  1V4H A;  2AZJ A;  4P0V A;  3TC1 A;  4KK2 A;  1UBV A;  1VG4 A;  4QPF A;  1UBY A;  2AET A;  3LGZ B;  2Z50 A;  1V4J A;  3AQC B;  2ZCR A;  3LK5 A;  5ILH A;  3ASX A;  1JFA A;  1N22 A;  3N6K F;  1ZW5 A;  3VJD A;  2P1C A;  3WSA A;  3ACW A;  3S9V A;  1HX9 A;  2O1O A;  4RYP A;  1YV5 A;  5HN7 A;  1WL3 A;  5DHI A;  3WJO A;  3NF2 A;  2VF6 A;  4EA1 A;  3M9U A;  4XQT F;  3KRP B;  1UBX A;  4LPG F;  5E8H A;  5ER8 A;  3PDE A;  5ILK A;  5EAT A;  2F9K F;  2ONH A;  3ZL6 A;  3WEI A;  2Z78 A;  4QXS F;  3N1W F;  1YYS A;  4E9Z A;  1EZF A;  2PS8 A;  2PS6 A;  2J5C A;  3ID0 A;  1HXC A;  3LGK A;  2E8X A;  5AYP A;  3N0G A;  1HM4 A;  1HXG A;  3VJB A;  5AEL A;  4L2X F;  5HN9 A;  5B0I A;  4DWB A;  3ICZ A;  3TFN A;  3CKE A;  5ILJ A;  1YJ4 A;  4LTZ A;  5DHK A;  3RYW A;  3N3L F;  1WL1 A;  2PS5 A;  3NPK A;  4LLT A;  3DYF A;  4DZW A;  4LUU A;  3Q2Q A;  2ONG A;  4FJQ A;  3WCH A;  1RQI A;  4JXY A;  4HD1 A;  2E95 A;  4GP2 A;  3SDT A;  1YQ7 A;  3KB9 A;  3CP6 A;  4P0W A;  1YYQ A;  3WCA A;  5B0K A;  3EFQ A;  1JFG A;  1V4I A;  2Z4Z A;  1DI1 A;  2E94 A;  4NKF A;  1N1Z A;  3WCD A;  5IL8 A;  3WEF A;  2ZCO A;  4NKE A;  3NPR A;  3KRF A;  1KIY A;  3SDQ A;  3LLW A;  3M02 A;  3V1X A;  5B02 A;  2J1O A;  5AFX A;  2Z4X A;  3WCG A;  4JYX A;  5JV0 F;  3LSN A;  4OKM A;  2PS7 A;  3ZOU A;  2Z7H A;  2RAH A;  4KPD A;  3KRA A;  3MAV A;  3LZ9 A;  5DZ2 A;  1V4E A;  4KKM A;  3APZ A;  3LDW A;  3OAB A;  3P5P A;  2Q9Z A;  5IL3 A;  3LEE A;  4DHD A;  2ZEV A;  3OYR A;  4H5C F;  4NFI F;  3IBA A;  5KSX F;  1N21 A;  2E92 A;  3KRA B;  4MC3 A;  3SAE A;  4XQR F;  2F8Z F;  5CG5 A;  3PYA A;  4WK5 A;  3ACX A;  5IMP A;  3VJ9 A;  3N49 F;  5IK6 A;  3WCC A;  4Q23 A;  3KRC A;  3N46 F;  2Q9Y A;  1WL2 A;  1RQJ A;  5ERM A;  5EAS A;  3PH7 A;  2OGD A;  5A0I A;  3TFV A;  2E4O A;  3SDR A;  5B01 A;  5IMI A;  3P5R A;  5IN8 A;  5JV1 F;  4LPH F;  5DGN F;  3S4J A;  4RXE A;  3KRC B;  4GP1 A;  1N24 A;  4OGU A;  3MZV A;  3KBK A;  2E91 A;  3DYG A;  4NFJ F;  2F8C F;  2E8U A;  2E8V A;  2ZCQ A;  5IVG A;  5B0M A;  3SDV A;  4DI5 A;  5JUZ F;  3N5H F;  3ADZ A;  4LIX A;  2H8O A;  5ILZ A;  4UMJ A;  1UBW A;  3LG5 A;  4JZB A;  4ZQ8 A;  3BNX A;  3KRO A;  5DJR F;  3QKC A;  2ZEU A;  4K10 A;  2ZCS A;  2AZK A;  5CG6 A;  3ZMC A;  3WJN A;  1VG3 A;  3N0F A;  2OPM A;  3N1V F;  2AEK A;  3NRI A;  4GAX A;  4OKZ A;  3V66 A;  1YYT A;  4LTV A;  4KVY A;  2Z7I A;  3B7L A;  2J1P A;  5IK9 A;  3ICM A;  4N9U A;  4H5E F;  4KVW A;  3VJC A;  3WEK A;  3LMD A;  4N1Z F;  3DYH A;  5DIQ F;  4LA6 A;  3WCB A;  3N5J F;  5E8K A;  4EA2 A;  5ILY A;  2PS4 A;  5E8L A;  4LFG A;  3ICK A;  3BNY A;  5HNA A;  2E8W A;  1HM7 A;  3RBM A;  3KRF B;  1VG6 A;  5ILD A;  4KQU A;  3RMG A;  5DW7 A;  3ZMB A;  5DGS F;  3ICN A;  3OAC A;  2Z4Y A;  2FOR A;  5DJV F;  1N1B A;  4LZ0 A; 
#chains in the Genus database with same CATH topology
 1FPS A;  3WEH A;  5HN8 A;  3UCA A;  2F7M F;  5ILI A;  3G4F A;  5I1U A;  3P8L A;  2Q80 A;  1YYR A;  2E8T A;  3LVS A;  3WJK A;  2E93 A;  3CC9 A;  3WCI A;  3OAB B;  5B03 A;  3AQ0 A;  3LJI A;  2OA6 A;  5IM1 A;  2Z52 A;  1YHM A;  4KQS A;  5AHU B;  3WSB A;  1YHL A;  4DWG A;  4LFV F;  3WCE A;  1KIZ A;  3V1V A;  4F6V A;  5ERO A;  3VJE A;  4LFE A;  5DGM F;  3KRP A;  4LLS A;  3WC9 A;  2F94 F;  4KVD A;  4JVJ F;  4LZ3 A;  3RYE A;  4KWD A;  3Q1O A;  3ZCD A;  3Q2Z A;  4DEM F;  4OMH A;  4H5D F;  4JXN A;  4LZC A;  3WEG A;  3N3D A;  2AZL A;  3EZ3 A;  1WY0 A;  4XQS F;  3TS7 A;  1WL0 A;  1N23 A;  3PYB A;  3VJ8 A;  2FTZ A;  5EAU A;  5ERN A;  4MC0 A;  5B0J A;  4E9U A;  5IKH A;  5H9D A;  1VG7 A;  2Q58 A;  3AE0 A;  1YYU A;  4KUX A;  4OMG A;  4KQ5 A;  2F92 F;  2QIS A;  3N45 F;  3TFP A;  4KVI A;  3WEJ A;  4P0X A;  1RTR A;  2Z4V A;  3WCL A;  1WMW A;  5JA0 F;  2Z4W A;  3IPI A;  3LOM A;  5IK0 A;  3KRO B;  3M00 A;  4JZX A;  2E90 A;  1WKZ A;  5IMN A;  4RNQ A;  3P8R A;  3SDU A;  4GA3 A;  4RXC A;  3G4D A;  1YHK A;  3M01 A;  1N20 A;  2F89 F;  4E1E A;  4NUA A;  3VJA A;  5A0K A;  5C05 A;  4LA5 A;  5B0L A;  5DJP F;  2EWG A;  2ZY1 A;  5B00 A;  4PVY F;  4KFA A;  4NG6 A;  3PKO A;  4F6X A;  3QQV A;  4PVX F;  4EA0 A;  5A0J A;  4LOB A;  2DH4 A;  3WCF A;  4RXD A;  2OPN A;  4FP4 A;  3Q30 A;  3AQB B;  1VG2 A;  3WCJ A;  1PS1 A;  4MC8 A;  3EGT A;  1HXA A;  2I19 A;  3OAC B;  3W7F A;  3WE9 A;  4F62 A;  3ACY A;  5JV2 F;  1DGP A;  4RXA A;  2AEL A;  4NFK F;  3WCM A;  4LXW A;  5IKA A;  4KPJ A;  3P41 A;  3M0G A;  1V4K A;  4DXJ A;  1V4H A;  2AZJ A;  4P0V A;  3TC1 A;  4KK2 A;  1UBV A;  1VG4 A;  4QPF A;  1UBY A;  2AET A;  3LGZ B;  2Z50 A;  1V4J A;  3AQC B;  2ZCR A;  3LK5 A;  5ILH A;  3ASX A;  1JFA A;  1N22 A;  3N6K F;  1ZW5 A;  3VJD A;  2P1C A;  3WSA A;  3ACW A;  3S9V A;  1HX9 A;  2O1O A;  4RYP A;  1YV5 A;  5HN7 A;  1WL3 A;  5DHI A;  3WJO A;  3NF2 A;  2VF6 A;  4EA1 A;  3M9U A;  4XQT F;  3KRP B;  1UBX A;  4LPG F;  5E8H A;  5ER8 A;  3PDE A;  5ILK A;  5EAT A;  2F9K F;  2ONH A;  3ZL6 A;  3WEI A;  2Z78 A;  4QXS F;  3N1W F;  1YYS A;  4E9Z A;  1EZF A;  2PS8 A;  2PS6 A;  2J5C A;  3ID0 A;  1HXC A;  3LGK A;  2E8X A;  5AYP A;  3N0G A;  1HM4 A;  1HXG A;  3VJB A;  5AEL A;  4L2X F;  5HN9 A;  5B0I A;  4DWB A;  3ICZ A;  3TFN A;  3CKE A;  5ILJ A;  1YJ4 A;  4LTZ A;  5DHK A;  3RYW A;  3N3L F;  1WL1 A;  2PS5 A;  3NPK A;  4LLT A;  3DYF A;  4DZW A;  4LUU A;  3Q2Q A;  2ONG A;  4FJQ A;  3WCH A;  1RQI A;  4JXY A;  4HD1 A;  2E95 A;  4GP2 A;  3SDT A;  1YQ7 A;  3KB9 A;  3CP6 A;  4P0W A;  1YYQ A;  3WCA A;  5B0K A;  3EFQ A;  1JFG A;  1V4I A;  2Z4Z A;  1DI1 A;  2E94 A;  4NKF A;  1N1Z A;  3WCD A;  5IL8 A;  3WEF A;  2ZCO A;  4NKE A;  3NPR A;  3KRF A;  1KIY A;  3SDQ A;  3LLW A;  3M02 A;  3V1X A;  5B02 A;  2J1O A;  5AFX A;  2Z4X A;  3WCG A;  4JYX A;  5JV0 F;  3LSN A;  4OKM A;  2PS7 A;  3ZOU A;  2Z7H A;  2RAH A;  4KPD A;  3KRA A;  3MAV A;  3LZ9 A;  5DZ2 A;  1V4E A;  4KKM A;  3APZ A;  3LDW A;  3OAB A;  3P5P A;  2Q9Z A;  5IL3 A;  3LEE A;  4DHD A;  2ZEV A;  3OYR A;  4H5C F;  4NFI F;  3IBA A;  5KSX F;  1N21 A;  2E92 A;  3KRA B;  4MC3 A;  3SAE A;  4XQR F;  2F8Z F;  5CG5 A;  3PYA A;  4WK5 A;  3ACX A;  5IMP A;  3VJ9 A;  3N49 F;  5IK6 A;  3WCC A;  4Q23 A;  3KRC A;  3N46 F;  2Q9Y A;  1WL2 A;  1RQJ A;  5ERM A;  5EAS A;  3PH7 A;  2OGD A;  5A0I A;  3TFV A;  2E4O A;  3SDR A;  5B01 A;  5IMI A;  3P5R A;  5IN8 A;  5JV1 F;  4LPH F;  5DGN F;  3S4J A;  4RXE A;  3KRC B;  4GP1 A;  1N24 A;  4OGU A;  3MZV A;  3KBK A;  2E91 A;  3DYG A;  4NFJ F;  2F8C F;  2E8U A;  2E8V A;  2ZCQ A;  5IVG A;  5B0M A;  3SDV A;  4DI5 A;  5JUZ F;  3N5H F;  3ADZ A;  4LIX A;  2H8O A;  5ILZ A;  4UMJ A;  1UBW A;  3LG5 A;  4JZB A;  4ZQ8 A;  3BNX A;  3KRO A;  5DJR F;  3QKC A;  2ZEU A;  4K10 A;  2ZCS A;  2AZK A;  5CG6 A;  3ZMC A;  3WJN A;  1VG3 A;  3N0F A;  2OPM A;  3N1V F;  2AEK A;  3NRI A;  4GAX A;  4OKZ A;  3V66 A;  1YYT A;  4LTV A;  4KVY A;  2Z7I A;  3B7L A;  2J1P A;  5IK9 A;  3ICM A;  4N9U A;  4H5E F;  4KVW A;  3VJC A;  3WEK A;  3LMD A;  4N1Z F;  3DYH A;  5DIQ F;  4LA6 A;  3WCB A;  3N5J F;  5E8K A;  4EA2 A;  5ILY A;  2PS4 A;  5E8L A;  4LFG A;  3ICK A;  3BNY A;  5HNA A;  2E8W A;  1HM7 A;  3RBM A;  3KRF B;  1VG6 A;  5ILD A;  4KQU A;  3RMG A;  5DW7 A;  3ZMB A;  5DGS F;  3ICN A;  3OAC A;  2Z4Y A;  2FOR A;  5DJV F;  1N1B A;  4LZ0 A; 
#chains in the Genus database with same CATH homology
 1FPS A;  3WEH A;  5HN8 A;  3UCA A;  2F7M F;  5ILI A;  3G4F A;  5I1U A;  3P8L A;  2Q80 A;  1YYR A;  2E8T A;  3LVS A;  3WJK A;  2E93 A;  3CC9 A;  3WCI A;  3OAB B;  5B03 A;  3AQ0 A;  3LJI A;  2OA6 A;  5IM1 A;  2Z52 A;  1YHM A;  4KQS A;  5AHU B;  3WSB A;  1YHL A;  4DWG A;  4LFV F;  3WCE A;  1KIZ A;  3V1V A;  4F6V A;  5ERO A;  3VJE A;  4LFE A;  5DGM F;  3KRP A;  4LLS A;  3WC9 A;  2F94 F;  4KVD A;  4JVJ F;  4LZ3 A;  3RYE A;  4KWD A;  3Q1O A;  3ZCD A;  3Q2Z A;  4DEM F;  4OMH A;  4H5D F;  4JXN A;  4LZC A;  3WEG A;  3N3D A;  2AZL A;  3EZ3 A;  1WY0 A;  4XQS F;  3TS7 A;  1WL0 A;  1N23 A;  3PYB A;  3VJ8 A;  2FTZ A;  5EAU A;  5ERN A;  4MC0 A;  5B0J A;  4E9U A;  5IKH A;  5H9D A;  1VG7 A;  2Q58 A;  3AE0 A;  1YYU A;  4KUX A;  4OMG A;  4KQ5 A;  2F92 F;  2QIS A;  3N45 F;  3TFP A;  4KVI A;  3WEJ A;  4P0X A;  1RTR A;  2Z4V A;  3WCL A;  1WMW A;  5JA0 F;  2Z4W A;  3IPI A;  3LOM A;  5IK0 A;  3KRO B;  3M00 A;  4JZX A;  2E90 A;  1WKZ A;  5IMN A;  4RNQ A;  3P8R A;  3SDU A;  4GA3 A;  4RXC A;  3G4D A;  1YHK A;  3M01 A;  1N20 A;  2F89 F;  4E1E A;  4NUA A;  3VJA A;  5A0K A;  5C05 A;  4LA5 A;  5B0L A;  5DJP F;  2EWG A;  2ZY1 A;  5B00 A;  4PVY F;  4KFA A;  4NG6 A;  3PKO A;  4F6X A;  3QQV A;  4PVX F;  4EA0 A;  5A0J A;  4LOB A;  2DH4 A;  3WCF A;  4RXD A;  2OPN A;  4FP4 A;  3Q30 A;  3AQB B;  1VG2 A;  3WCJ A;  1PS1 A;  4MC8 A;  3EGT A;  1HXA A;  2I19 A;  3OAC B;  3W7F A;  3WE9 A;  4F62 A;  3ACY A;  5JV2 F;  1DGP A;  4RXA A;  2AEL A;  4NFK F;  3WCM A;  4LXW A;  5IKA A;  4KPJ A;  3P41 A;  3M0G A;  1V4K A;  4DXJ A;  1V4H A;  2AZJ A;  4P0V A;  3TC1 A;  4KK2 A;  1UBV A;  1VG4 A;  4QPF A;  1UBY A;  2AET A;  3LGZ B;  2Z50 A;  1V4J A;  3AQC B;  2ZCR A;  3LK5 A;  5ILH A;  3ASX A;  1JFA A;  1N22 A;  3N6K F;  1ZW5 A;  3VJD A;  2P1C A;  3WSA A;  3ACW A;  3S9V A;  1HX9 A;  2O1O A;  4RYP A;  1YV5 A;  5HN7 A;  1WL3 A;  5DHI A;  3WJO A;  3NF2 A;  2VF6 A;  4EA1 A;  3M9U A;  4XQT F;  3KRP B;  1UBX A;  4LPG F;  5E8H A;  5ER8 A;  3PDE A;  5ILK A;  5EAT A;  2F9K F;  2ONH A;  3ZL6 A;  3WEI A;  2Z78 A;  4QXS F;  3N1W F;  1YYS A;  4E9Z A;  1EZF A;  2PS8 A;  2PS6 A;  2J5C A;  3ID0 A;  1HXC A;  3LGK A;  2E8X A;  5AYP A;  3N0G A;  1HM4 A;  1HXG A;  3VJB A;  5AEL A;  4L2X F;  5HN9 A;  5B0I A;  4DWB A;  3ICZ A;  3TFN A;  3CKE A;  5ILJ A;  1YJ4 A;  4LTZ A;  5DHK A;  3RYW A;  3N3L F;  1WL1 A;  2PS5 A;  3NPK A;  4LLT A;  3DYF A;  4DZW A;  4LUU A;  3Q2Q A;  2ONG A;  4FJQ A;  3WCH A;  1RQI A;  4JXY A;  4HD1 A;  2E95 A;  4GP2 A;  3SDT A;  1YQ7 A;  3KB9 A;  3CP6 A;  4P0W A;  1YYQ A;  3WCA A;  5B0K A;  3EFQ A;  1JFG A;  1V4I A;  2Z4Z A;  1DI1 A;  2E94 A;  4NKF A;  1N1Z A;  3WCD A;  5IL8 A;  3WEF A;  2ZCO A;  4NKE A;  3NPR A;  3KRF A;  1KIY A;  3SDQ A;  3LLW A;  3M02 A;  3V1X A;  5B02 A;  2J1O A;  5AFX A;  2Z4X A;  3WCG A;  4JYX A;  5JV0 F;  3LSN A;  4OKM A;  2PS7 A;  3ZOU A;  2Z7H A;  2RAH A;  4KPD A;  3KRA A;  3MAV A;  3LZ9 A;  5DZ2 A;  1V4E A;  4KKM A;  3APZ A;  3LDW A;  3OAB A;  3P5P A;  2Q9Z A;  5IL3 A;  3LEE A;  4DHD A;  2ZEV A;  3OYR A;  4H5C F;  4NFI F;  3IBA A;  5KSX F;  1N21 A;  2E92 A;  3KRA B;  4MC3 A;  3SAE A;  4XQR F;  2F8Z F;  5CG5 A;  3PYA A;  4WK5 A;  3ACX A;  5IMP A;  3VJ9 A;  3N49 F;  5IK6 A;  3WCC A;  4Q23 A;  3KRC A;  3N46 F;  2Q9Y A;  1WL2 A;  1RQJ A;  5ERM A;  5EAS A;  3PH7 A;  2OGD A;  5A0I A;  3TFV A;  2E4O A;  3SDR A;  5B01 A;  5IMI A;  3P5R A;  5IN8 A;  5JV1 F;  4LPH F;  5DGN F;  3S4J A;  4RXE A;  3KRC B;  4GP1 A;  1N24 A;  4OGU A;  3MZV A;  3KBK A;  2E91 A;  3DYG A;  4NFJ F;  2F8C F;  2E8U A;  2E8V A;  2ZCQ A;  5IVG A;  5B0M A;  3SDV A;  4DI5 A;  5JUZ F;  3N5H F;  3ADZ A;  4LIX A;  2H8O A;  5ILZ A;  4UMJ A;  1UBW A;  3LG5 A;  4JZB A;  4ZQ8 A;  3BNX A;  3KRO A;  5DJR F;  3QKC A;  2ZEU A;  4K10 A;  2ZCS A;  2AZK A;  5CG6 A;  3ZMC A;  3WJN A;  1VG3 A;  3N0F A;  2OPM A;  3N1V F;  2AEK A;  3NRI A;  4GAX A;  4OKZ A;  3V66 A;  1YYT A;  4LTV A;  4KVY A;  2Z7I A;  3B7L A;  2J1P A;  5IK9 A;  3ICM A;  4N9U A;  4H5E F;  4KVW A;  3VJC A;  3WEK A;  3LMD A;  4N1Z F;  3DYH A;  5DIQ F;  4LA6 A;  3WCB A;  3N5J F;  5E8K A;  4EA2 A;  5ILY A;  2PS4 A;  5E8L A;  4LFG A;  3ICK A;  3BNY A;  5HNA A;  2E8W A;  1HM7 A;  3RBM A;  3KRF B;  1VG6 A;  5ILD A;  4KQU A;  3RMG A;  5DW7 A;  3ZMB A;  5DGS F;  3ICN A;  3OAC A;  2Z4Y A;  2FOR A;  5DJV F;  1N1B A;  4LZ0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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