2F7MF

Crystal structure of unliganded human fpps
Total Genus 130
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
130
sequence length
341
structure length
341
Chain Sequence
VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl Diphosphate Synthase
total genus 130
structure length 341
sequence length 341
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f7mF00
3RBMA 3CP6A 4KVWA 4KPJA 2E93A 5E8LA 2E94A 3KRPB 3ZMCA 3SAEA 5IKHA 3RMGA 3LGZB 3WEFA 4KQUA 4NUAA 3NPKA 4EA1A 4KVYA 4RXAA 3QKCA 1V4HA 2F92F 5HNAA 1N24A 1WL3A 2ZEUA 3KRCB 1WMWA 3WCEA 4KVDA 5DGNF 5B00A 1V4JA 3P5PA 3ACYA 3AQ0A 3LG5A 5AFXA 5CG5A 3Q2ZA 4PVXF 4XQRF 3PYAA 4LPHF 5ILYA 3WEHA 2PS5A 3WJOA 3PKOA 5ILHA 3KROB 3B7LA 3ASXA 3G4FA 5HN7A 5B02A 2F7MF 1HM7A 2AZKA 2FTZA 1N1BA 2F89F 3WC9A 1WL1A 2E4OA 4DWBA 4DXJA 1VG7A 4E9ZA 3PYBA 2J5CA 3AQCB 5IL3A 5DGSF 3SDTA 3MZVA 4KQ5A 2PS8A 4MC8A 4RXCA 5HN8A 3VJDA 1RQJA 1V4KA 1UBVA 3SDVA 3N5HF 3WCHA 1YHLA 3OABB 4NG6A 3V1XA 2J1PA 2F9KF 3SDRA 3V1VA 3KRAB 2AETA 3WEJA 1VG3A 2OPMA 2F8ZF 2ZCSA 3KB9A 4JXNA 4ZQ8A 2Z52A 4F6XA 4LA5A 3WE9A 4PVYF 3TC1A 3WEGA 1WL2A 3WSBA 1RQIA 2FORA 3W7FA 5B01A 3ZCDA 3BNYA 4GAXA 2VF6A 3LK5A 3LGKA 4LOBA 2E8VA 4H5CF 3KRFA 1YYRA 1V4IA 3WEIA 4LPGF 4LTVA 5E8HA 1YQ7A 2F94F 3VJBA 4HD1A 3VJ9A 3ICMA 2ONHA 4QPFA 1JFAA 4KK2A 2E8WA 1V4EA 1WY0A 5EROA 4DHDA 4KQSA 5A0KA 5KSXF 4LFGA 4NFKF 5EASA 4RXDA 2OPNA 2E95A 3ZMBA 5ERNA 3BNXA 5B0KA 3WCDA 4H5DF 1DGPA 2ONGA 4P0WA 3LDWA 3M02A 5AHUB 3N45F 2Z4ZA 3P5RA 5CG6A 4JZBA 4JZXA 5IMNA 3LVSA 1JFGA 4H5EF 3TFVA 1N21A 5ILZA 1RTRA 2OGDA 5JA0F 5DGMF 2Z78A 4DWGA 4MC3A 2AZLA 2EWGA 2Q9ZA 5B0JA 3LMDA 2Q9YA 2RAHA 3ICNA 2AEKA 3P8RA 1KIYA 3TFPA 2QISA 3S4JA 3KROA 1DI1A 1HXGA 1VG6A 3OACB 1YYUA 3DYGA 1VG4A 5ILDA 3VJEA 1HXCA 3WJKA 3WCCA 4JYXA 2H8OA 4L2XF 2Z4YA 2E8TA 3WSAA 5ILJA 4MC0A 4LUUA 3M01A 5AYPA 3LEEA 3ICZA 1YHKA 5B0IA 3WCMA 3SDQA 3MAVA 5DJRF 3VJAA 5AELA 2ZEVA 3ZOUA 5JV1F 2PS7A 3G4DA 1YJ4A 2OA6A 2Q58A 4P0XA 5JUZF 3S9VA 2Z7HA 3EZ3A 5DJPF 3OABA 3IBAA 5H9DA 3IPIA 3ID0A 3N5JF 4LZCA 5IKAA 3P41A 2E90A 5IMPA 5IK6A 3TS7A 4EA2A 2AZJA 4JVJF 1N1ZA 4OMHA 1WL0A 4LIXA 2P1CA 3NF2A 3Q30A 5DJVF 3QQVA 3SDUA 5EAUA 3M9UA 3Q1OA 4LZ3A 4OKMA 3RYEA 4UMJA 4OMGA 1KIZA 1FPSA 5DW7A 1YYTA 5E8KA 5EATA 3WCGA 2I19A 4LZ0A 3RYWA 5DZ2A 5IM1A 3KRPA 2Z4WA 4LLTA 4K10A 3N6KF 5A0JA 4E1EA 3PH7A 3WJNA 1YHMA 3WCLA 5B03A 4XQSF 4N1ZF 1YYQA 5IK9A 2E8XA 1EZFA 3WCAA 1YV5A 2O1OA 3KRCA 5B0LA 4GA3A 4KFAA 4GP1A 3UCAA 1UBYA 2Z7IA 4LLSA 4XQTF 4FJQA 5ILKA 1HX9A 5JV2F 2E8UA 2Z4VA 3N1VF 3LOMA 4F6VA 4LTZA 3WCJA 3WEKA 3AQBB 4DZWA 5ILIA 4WK5A 3LJIA 4EA0A 4LFVF 5A0IA 5IMIA 4GP2A 4OKZA 2J1OA 4P0VA 2AELA 4FP4A 1UBXA 3DYFA 3V66A 2F8CF 3M0GA 5ERMA 3EFQA 4NFIF 3LZ9A 3DYHA 3KBKA 3N0FA 1PS1A 2PS6A 3ADZA 5C05A 4LXWA 4E9UA 3LSNA 4JXYA 2ZCOA 3OACA 4RYPA 3N0GA 4KVIA 3NPRA 4RXEA 3ZL6A 1UBWA 4KKMA 5IK0A 3N46F 4F62A 3VJ8A 2Z50A 4DEMF 3N3LF 4RNQA 4OGUA 3CC9A 3OYRA 1N22A 2Z4XA 3NRIA 5HN9A 2E91A 4Q23A 4NKFA 3EGTA 3M00A 1VG2A 3Q2QA 5IN8A 2E92A 2ZY1A 1N23A 2ZCQA 1HM4A 4KUXA 4DI5A 1HXAA 5DHKA 1WKZA 3KRAA 4KPDA 3APZA 5I1UA 1YYSA 4LFEA 3AE0A 1N20A 2ZCRA 4LA6A 5ER8A 3TFNA 2Q80A 4KWDA 3WCBA 5B0MA 3N49F 4QXSF 3N3DA 3CKEA 4NFJF 5DHIA 3KRFB 4N9UA 3ICKA 4NKEA 3WCFA 1ZW5A 3P8LA 2DH4A 3N1WF 3ACWA 3VJCA 5JV0F 2PS4A 5DIQF 3WCIA 3ACXA 5IVGA 3PDEA 3LLWA 5IL8A
chains in the Genus database with same CATH superfamily
3RBMA 3CP6A 4KVWA 4KPJA 2E93A 5E8LA 2E94A 3KRPB 3ZMCA 3SAEA 5IKHA 3RMGA 3LGZB 3WEFA 4KQUA 4NUAA 3NPKA 4EA1A 4KVYA 4RXAA 3QKCA 1V4HA 2F92F 5HNAA 1N24A 1WL3A 2ZEUA 3KRCB 1WMWA 3WCEA 4KVDA 5DGNF 5B00A 1V4JA 3P5PA 3ACYA 3AQ0A 3LG5A 5AFXA 5CG5A 3Q2ZA 4PVXF 4XQRF 3PYAA 4LPHF 5ILYA 3WEHA 2PS5A 3WJOA 3PKOA 5ILHA 3KROB 3B7LA 3ASXA 3G4FA 5HN7A 5B02A 2F7MF 1HM7A 2AZKA 2FTZA 1N1BA 2F89F 3WC9A 1WL1A 2E4OA 4DWBA 4DXJA 1VG7A 4E9ZA 3PYBA 2J5CA 3AQCB 5IL3A 5DGSF 3SDTA 3MZVA 4KQ5A 2PS8A 4MC8A 4RXCA 5HN8A 3VJDA 1RQJA 1V4KA 1UBVA 3SDVA 3N5HF 3WCHA 1YHLA 3OABB 4NG6A 3V1XA 2J1PA 2F9KF 3SDRA 3V1VA 3KRAB 2AETA 3WEJA 1VG3A 2OPMA 2F8ZF 2ZCSA 3KB9A 4JXNA 4ZQ8A 2Z52A 4F6XA 4LA5A 3WE9A 4PVYF 3TC1A 3WEGA 1WL2A 3WSBA 1RQIA 2FORA 3W7FA 5B01A 3ZCDA 3BNYA 4GAXA 2VF6A 3LK5A 3LGKA 4LOBA 2E8VA 4H5CF 3KRFA 1YYRA 1V4IA 3WEIA 4LPGF 4LTVA 5E8HA 1YQ7A 2F94F 3VJBA 4HD1A 3VJ9A 3ICMA 2ONHA 4QPFA 1JFAA 4KK2A 2E8WA 1V4EA 1WY0A 5EROA 4DHDA 4KQSA 5A0KA 5KSXF 4LFGA 4NFKF 5EASA 4RXDA 2OPNA 2E95A 3ZMBA 5ERNA 3BNXA 5B0KA 3WCDA 4H5DF 1DGPA 2ONGA 4P0WA 3LDWA 3M02A 5AHUB 3N45F 2Z4ZA 3P5RA 5CG6A 4JZBA 4JZXA 5IMNA 3LVSA 1JFGA 4H5EF 3TFVA 1N21A 5ILZA 1RTRA 2OGDA 5JA0F 5DGMF 2Z78A 4DWGA 4MC3A 2AZLA 2EWGA 2Q9ZA 5B0JA 3LMDA 2Q9YA 2RAHA 3ICNA 2AEKA 3P8RA 1KIYA 3TFPA 2QISA 3S4JA 3KROA 1DI1A 1HXGA 1VG6A 3OACB 1YYUA 3DYGA 1VG4A 5ILDA 3VJEA 1HXCA 3WJKA 3WCCA 4JYXA 2H8OA 4L2XF 2Z4YA 2E8TA 3WSAA 5ILJA 4MC0A 4LUUA 3M01A 5AYPA 3LEEA 3ICZA 1YHKA 5B0IA 3WCMA 3SDQA 3MAVA 5DJRF 3VJAA 5AELA 2ZEVA 3ZOUA 5JV1F 2PS7A 3G4DA 1YJ4A 2OA6A 2Q58A 4P0XA 5JUZF 3S9VA 2Z7HA 3EZ3A 5DJPF 3OABA 3IBAA 5H9DA 3IPIA 3ID0A 3N5JF 4LZCA 5IKAA 3P41A 2E90A 5IMPA 5IK6A 3TS7A 4EA2A 2AZJA 4JVJF 1N1ZA 4OMHA 1WL0A 4LIXA 2P1CA 3NF2A 3Q30A 5DJVF 3QQVA 3SDUA 5EAUA 3M9UA 3Q1OA 4LZ3A 4OKMA 3RYEA 4UMJA 4OMGA 1KIZA 1FPSA 5DW7A 1YYTA 5E8KA 5EATA 3WCGA 2I19A 4LZ0A 3RYWA 5DZ2A 5IM1A 3KRPA 2Z4WA 4LLTA 4K10A 3N6KF 5A0JA 4E1EA 3PH7A 3WJNA 1YHMA 3WCLA 5B03A 4XQSF 4N1ZF 1YYQA 5IK9A 2E8XA 1EZFA 3WCAA 1YV5A 2O1OA 3KRCA 5B0LA 4GA3A 4KFAA 4GP1A 3UCAA 1UBYA 2Z7IA 4LLSA 4XQTF 4FJQA 5ILKA 1HX9A 5JV2F 2E8UA 2Z4VA 3N1VF 3LOMA 4F6VA 4LTZA 3WCJA 3WEKA 3AQBB 4DZWA 5ILIA 4WK5A 3LJIA 4EA0A 4LFVF 5A0IA 5IMIA 4GP2A 4OKZA 2J1OA 4P0VA 2AELA 4FP4A 1UBXA 3DYFA 3V66A 2F8CF 3M0GA 5ERMA 3EFQA 4NFIF 3LZ9A 3DYHA 3KBKA 3N0FA 1PS1A 2PS6A 3ADZA 5C05A 4LXWA 4E9UA 3LSNA 4JXYA 2ZCOA 3OACA 4RYPA 3N0GA 4KVIA 3NPRA 4RXEA 3ZL6A 1UBWA 4KKMA 5IK0A 3N46F 4F62A 3VJ8A 2Z50A 4DEMF 3N3LF 4RNQA 4OGUA 3CC9A 3OYRA 1N22A 2Z4XA 3NRIA 5HN9A 2E91A 4Q23A 4NKFA 3EGTA 3M00A 1VG2A 3Q2QA 5IN8A 2E92A 2ZY1A 1N23A 2ZCQA 1HM4A 4KUXA 4DI5A 1HXAA 5DHKA 1WKZA 3KRAA 4KPDA 3APZA 5I1UA 1YYSA 4LFEA 3AE0A 1N20A 2ZCRA 4LA6A 5ER8A 3TFNA 2Q80A 4KWDA 3WCBA 5B0MA 3N49F 4QXSF 3N3DA 3CKEA 4NFJF 5DHIA 3KRFB 4N9UA 3ICKA 4NKEA 3WCFA 1ZW5A 3P8LA 2DH4A 3N1WF 3ACWA 3VJCA 5JV0F 2PS4A 5DIQF 3WCIA 3ACXA 5IVGA 3PDEA 3LLWA 5IL8A
chains in the Genus database with same CATH topology
3RBMA 3CP6A 4KVWA 4KPJA 2E93A 5E8LA 2E94A 3KRPB 3ZMCA 3SAEA 5IKHA 3RMGA 3LGZB 3WEFA 4KQUA 4NUAA 3NPKA 4EA1A 4KVYA 4RXAA 3QKCA 1V4HA 2F92F 5HNAA 1N24A 1WL3A 2ZEUA 3KRCB 1WMWA 3WCEA 4KVDA 5DGNF 5B00A 1V4JA 3P5PA 3ACYA 3AQ0A 3LG5A 5AFXA 5CG5A 3Q2ZA 4PVXF 4XQRF 3PYAA 4LPHF 5ILYA 3WEHA 2PS5A 3WJOA 3PKOA 5ILHA 3KROB 3B7LA 3ASXA 3G4FA 5HN7A 5B02A 2F7MF 1HM7A 2AZKA 2FTZA 1N1BA 2F89F 3WC9A 1WL1A 2E4OA 4DWBA 4DXJA 1VG7A 4E9ZA 3PYBA 2J5CA 3AQCB 5IL3A 5DGSF 3SDTA 3MZVA 4KQ5A 2PS8A 4MC8A 4RXCA 5HN8A 3VJDA 1RQJA 1V4KA 1UBVA 3SDVA 3N5HF 3WCHA 1YHLA 3OABB 4NG6A 3V1XA 2J1PA 2F9KF 3SDRA 3V1VA 3KRAB 2AETA 3WEJA 1VG3A 2OPMA 2F8ZF 2ZCSA 3KB9A 4JXNA 4ZQ8A 2Z52A 4F6XA 4LA5A 3WE9A 4PVYF 3TC1A 3WEGA 1WL2A 3WSBA 1RQIA 2FORA 3W7FA 5B01A 3ZCDA 3BNYA 4GAXA 2VF6A 3LK5A 3LGKA 4LOBA 2E8VA 4H5CF 3KRFA 1YYRA 1V4IA 3WEIA 4LPGF 4LTVA 5E8HA 1YQ7A 2F94F 3VJBA 4HD1A 3VJ9A 3ICMA 2ONHA 4QPFA 1JFAA 4KK2A 2E8WA 1V4EA 1WY0A 5EROA 4DHDA 4KQSA 5A0KA 5KSXF 4LFGA 4NFKF 5EASA 4RXDA 2OPNA 2E95A 3ZMBA 5ERNA 3BNXA 5B0KA 3WCDA 4H5DF 1DGPA 2ONGA 4P0WA 3LDWA 3M02A 5AHUB 3N45F 2Z4ZA 3P5RA 5CG6A 4JZBA 4JZXA 5IMNA 3LVSA 1JFGA 4H5EF 3TFVA 1N21A 5ILZA 1RTRA 2OGDA 5JA0F 5DGMF 2Z78A 4DWGA 4MC3A 2AZLA 2EWGA 2Q9ZA 5B0JA 3LMDA 2Q9YA 2RAHA 3ICNA 2AEKA 3P8RA 1KIYA 3TFPA 2QISA 3S4JA 3KROA 1DI1A 1HXGA 1VG6A 3OACB 1YYUA 3DYGA 1VG4A 5ILDA 3VJEA 1HXCA 3WJKA 3WCCA 4JYXA 2H8OA 4L2XF 2Z4YA 2E8TA 3WSAA 5ILJA 4MC0A 4LUUA 3M01A 5AYPA 3LEEA 3ICZA 1YHKA 5B0IA 3WCMA 3SDQA 3MAVA 5DJRF 3VJAA 5AELA 2ZEVA 3ZOUA 5JV1F 2PS7A 3G4DA 1YJ4A 2OA6A 2Q58A 4P0XA 5JUZF 3S9VA 2Z7HA 3EZ3A 5DJPF 3OABA 3IBAA 5H9DA 3IPIA 3ID0A 3N5JF 4LZCA 5IKAA 3P41A 2E90A 5IMPA 5IK6A 3TS7A 4EA2A 2AZJA 4JVJF 1N1ZA 4OMHA 1WL0A 4LIXA 2P1CA 3NF2A 3Q30A 5DJVF 3QQVA 3SDUA 5EAUA 3M9UA 3Q1OA 4LZ3A 4OKMA 3RYEA 4UMJA 4OMGA 1KIZA 1FPSA 5DW7A 1YYTA 5E8KA 5EATA 3WCGA 2I19A 4LZ0A 3RYWA 5DZ2A 5IM1A 3KRPA 2Z4WA 4LLTA 4K10A 3N6KF 5A0JA 4E1EA 3PH7A 3WJNA 1YHMA 3WCLA 5B03A 4XQSF 4N1ZF 1YYQA 5IK9A 2E8XA 1EZFA 3WCAA 1YV5A 2O1OA 3KRCA 5B0LA 4GA3A 4KFAA 4GP1A 3UCAA 1UBYA 2Z7IA 4LLSA 4XQTF 4FJQA 5ILKA 1HX9A 5JV2F 2E8UA 2Z4VA 3N1VF 3LOMA 4F6VA 4LTZA 3WCJA 3WEKA 3AQBB 4DZWA 5ILIA 4WK5A 3LJIA 4EA0A 4LFVF 5A0IA 5IMIA 4GP2A 4OKZA 2J1OA 4P0VA 2AELA 4FP4A 1UBXA 3DYFA 3V66A 2F8CF 3M0GA 5ERMA 3EFQA 4NFIF 3LZ9A 3DYHA 3KBKA 3N0FA 1PS1A 2PS6A 3ADZA 5C05A 4LXWA 4E9UA 3LSNA 4JXYA 2ZCOA 3OACA 4RYPA 3N0GA 4KVIA 3NPRA 4RXEA 3ZL6A 1UBWA 4KKMA 5IK0A 3N46F 4F62A 3VJ8A 2Z50A 4DEMF 3N3LF 4RNQA 4OGUA 3CC9A 3OYRA 1N22A 2Z4XA 3NRIA 5HN9A 2E91A 4Q23A 4NKFA 3EGTA 3M00A 1VG2A 3Q2QA 5IN8A 2E92A 2ZY1A 1N23A 2ZCQA 1HM4A 4KUXA 4DI5A 1HXAA 5DHKA 1WKZA 3KRAA 4KPDA 3APZA 5I1UA 1YYSA 4LFEA 3AE0A 1N20A 2ZCRA 4LA6A 5ER8A 3TFNA 2Q80A 4KWDA 3WCBA 5B0MA 3N49F 4QXSF 3N3DA 3CKEA 4NFJF 5DHIA 3KRFB 4N9UA 3ICKA 4NKEA 3WCFA 1ZW5A 3P8LA 2DH4A 3N1WF 3ACWA 3VJCA 5JV0F 2PS4A 5DIQF 3WCIA 3ACXA 5IVGA 3PDEA 3LLWA 5IL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RBM A;  3CP6 A;  4KVW A;  4KPJ A;  2E93 A;  5E8L A;  2E94 A;  3KRP B;  3ZMC A;  3SAE A;  5IKH A;  3RMG A;  3LGZ B;  3WEF A;  4KQU A;  4NUA A;  3NPK A;  4EA1 A;  4KVY A;  4RXA A;  3QKC A;  1V4H A;  2F92 F;  5HNA A;  1N24 A;  1WL3 A;  2ZEU A;  3KRC B;  1WMW A;  3WCE A;  4KVD A;  5DGN F;  5B00 A;  1V4J A;  3P5P A;  3ACY A;  3AQ0 A;  3LG5 A;  5AFX A;  5CG5 A;  3Q2Z A;  4PVX F;  4XQR F;  3PYA A;  4LPH F;  5ILY A;  3WEH A;  2PS5 A;  3WJO A;  3PKO A;  5ILH A;  3KRO B;  3B7L A;  3ASX A;  3G4F A;  5HN7 A;  5B02 A;  2F7M F;  1HM7 A;  2AZK A;  2FTZ A;  1N1B A;  2F89 F;  3WC9 A;  1WL1 A;  2E4O A;  4DWB A;  4DXJ A;  1VG7 A;  4E9Z A;  3PYB A;  2J5C A;  3AQC B;  5IL3 A;  5DGS F;  3SDT A;  3MZV A;  4KQ5 A;  2PS8 A;  4MC8 A;  4RXC A;  5HN8 A;  3VJD A;  1RQJ A;  1V4K A;  1UBV A;  3SDV A;  3N5H F;  3WCH A;  1YHL A;  3OAB B;  4NG6 A;  3V1X A;  2J1P A;  2F9K F;  3SDR A;  3V1V A;  3KRA B;  2AET A;  3WEJ A;  1VG3 A;  2OPM A;  2F8Z F;  2ZCS A;  3KB9 A;  4JXN A;  4ZQ8 A;  2Z52 A;  4F6X A;  4LA5 A;  3WE9 A;  4PVY F;  3TC1 A;  3WEG A;  1WL2 A;  3WSB A;  1RQI A;  2FOR A;  3W7F A;  5B01 A;  3ZCD A;  3BNY A;  4GAX A;  2VF6 A;  3LK5 A;  3LGK A;  4LOB A;  2E8V A;  4H5C F;  3KRF A;  1YYR A;  1V4I A;  3WEI A;  4LPG F;  4LTV A;  5E8H A;  1YQ7 A;  2F94 F;  3VJB A;  4HD1 A;  3VJ9 A;  3ICM A;  2ONH A;  4QPF A;  1JFA A;  4KK2 A;  2E8W A;  1V4E A;  1WY0 A;  5ERO A;  4DHD A;  4KQS A;  5A0K A;  5KSX F;  4LFG A;  4NFK F;  5EAS A;  4RXD A;  2OPN A;  2E95 A;  3ZMB A;  5ERN A;  3BNX A;  5B0K A;  3WCD A;  4H5D F;  1DGP A;  2ONG A;  4P0W A;  3LDW A;  3M02 A;  5AHU B;  3N45 F;  2Z4Z A;  3P5R A;  5CG6 A;  4JZB A;  4JZX A;  5IMN A;  3LVS A;  1JFG A;  4H5E F;  3TFV A;  1N21 A;  5ILZ A;  1RTR A;  2OGD A;  5JA0 F;  5DGM F;  2Z78 A;  4DWG A;  4MC3 A;  2AZL A;  2EWG A;  2Q9Z A;  5B0J A;  3LMD A;  2Q9Y A;  2RAH A;  3ICN A;  2AEK A;  3P8R A;  1KIY A;  3TFP A;  2QIS A;  3S4J A;  3KRO A;  1DI1 A;  1HXG A;  1VG6 A;  3OAC B;  1YYU A;  3DYG A;  1VG4 A;  5ILD A;  3VJE A;  1HXC A;  3WJK A;  3WCC A;  4JYX A;  2H8O A;  4L2X F;  2Z4Y A;  2E8T A;  3WSA A;  5ILJ A;  4MC0 A;  4LUU A;  3M01 A;  5AYP A;  3LEE A;  3ICZ A;  1YHK A;  5B0I A;  3WCM A;  3SDQ A;  3MAV A;  5DJR F;  3VJA A;  5AEL A;  2ZEV A;  3ZOU A;  5JV1 F;  2PS7 A;  3G4D A;  1YJ4 A;  2OA6 A;  2Q58 A;  4P0X A;  5JUZ F;  3S9V A;  2Z7H A;  3EZ3 A;  5DJP F;  3OAB A;  3IBA A;  5H9D A;  3IPI A;  3ID0 A;  3N5J F;  4LZC A;  5IKA A;  3P41 A;  2E90 A;  5IMP A;  5IK6 A;  3TS7 A;  4EA2 A;  2AZJ A;  4JVJ F;  1N1Z A;  4OMH A;  1WL0 A;  4LIX A;  2P1C A;  3NF2 A;  3Q30 A;  5DJV F;  3QQV A;  3SDU A;  5EAU A;  3M9U A;  3Q1O A;  4LZ3 A;  4OKM A;  3RYE A;  4UMJ A;  4OMG A;  1KIZ A;  1FPS A;  5DW7 A;  1YYT A;  5E8K A;  5EAT A;  3WCG A;  2I19 A;  4LZ0 A;  3RYW A;  5DZ2 A;  5IM1 A;  3KRP A;  2Z4W A;  4LLT A;  4K10 A;  3N6K F;  5A0J A;  4E1E A;  3PH7 A;  3WJN A;  1YHM A;  3WCL A;  5B03 A;  4XQS F;  4N1Z F;  1YYQ A;  5IK9 A;  2E8X A;  1EZF A;  3WCA A;  1YV5 A;  2O1O A;  3KRC A;  5B0L A;  4GA3 A;  4KFA A;  4GP1 A;  3UCA A;  1UBY A;  2Z7I A;  4LLS A;  4XQT F;  4FJQ A;  5ILK A;  1HX9 A;  5JV2 F;  2E8U A;  2Z4V A;  3N1V F;  3LOM A;  4F6V A;  4LTZ A;  3WCJ A;  3WEK A;  3AQB B;  4DZW A;  5ILI A;  4WK5 A;  3LJI A;  4EA0 A;  4LFV F;  5A0I A;  5IMI A;  4GP2 A;  4OKZ A;  2J1O A;  4P0V A;  2AEL A;  4FP4 A;  1UBX A;  3DYF A;  3V66 A;  2F8C F;  3M0G A;  5ERM A;  3EFQ A;  4NFI F;  3LZ9 A;  3DYH A;  3KBK A;  3N0F A;  1PS1 A;  2PS6 A;  3ADZ A;  5C05 A;  4LXW A;  4E9U A;  3LSN A;  4JXY A;  2ZCO A;  3OAC A;  4RYP A;  3N0G A;  4KVI A;  3NPR A;  4RXE A;  3ZL6 A;  1UBW A;  4KKM A;  5IK0 A;  3N46 F;  4F62 A;  3VJ8 A;  2Z50 A;  4DEM F;  3N3L F;  4RNQ A;  4OGU A;  3CC9 A;  3OYR A;  1N22 A;  2Z4X A;  3NRI A;  5HN9 A;  2E91 A;  4Q23 A;  4NKF A;  3EGT A;  3M00 A;  1VG2 A;  3Q2Q A;  5IN8 A;  2E92 A;  2ZY1 A;  1N23 A;  2ZCQ A;  1HM4 A;  4KUX A;  4DI5 A;  1HXA A;  5DHK A;  1WKZ A;  3KRA A;  4KPD A;  3APZ A;  5I1U A;  1YYS A;  4LFE A;  3AE0 A;  1N20 A;  2ZCR A;  4LA6 A;  5ER8 A;  3TFN A;  2Q80 A;  4KWD A;  3WCB A;  5B0M A;  3N49 F;  4QXS F;  3N3D A;  3CKE A;  4NFJ F;  5DHI A;  3KRF B;  4N9U A;  3ICK A;  4NKE A;  3WCF A;  1ZW5 A;  3P8L A;  2DH4 A;  3N1W F;  3ACW A;  3VJC A;  5JV0 F;  2PS4 A;  5DIQ F;  3WCI A;  3ACX A;  5IVG A;  3PDE A;  3LLW A;  5IL8 A; 
#chains in the Genus database with same CATH topology
 3RBM A;  3CP6 A;  4KVW A;  4KPJ A;  2E93 A;  5E8L A;  2E94 A;  3KRP B;  3ZMC A;  3SAE A;  5IKH A;  3RMG A;  3LGZ B;  3WEF A;  4KQU A;  4NUA A;  3NPK A;  4EA1 A;  4KVY A;  4RXA A;  3QKC A;  1V4H A;  2F92 F;  5HNA A;  1N24 A;  1WL3 A;  2ZEU A;  3KRC B;  1WMW A;  3WCE A;  4KVD A;  5DGN F;  5B00 A;  1V4J A;  3P5P A;  3ACY A;  3AQ0 A;  3LG5 A;  5AFX A;  5CG5 A;  3Q2Z A;  4PVX F;  4XQR F;  3PYA A;  4LPH F;  5ILY A;  3WEH A;  2PS5 A;  3WJO A;  3PKO A;  5ILH A;  3KRO B;  3B7L A;  3ASX A;  3G4F A;  5HN7 A;  5B02 A;  2F7M F;  1HM7 A;  2AZK A;  2FTZ A;  1N1B A;  2F89 F;  3WC9 A;  1WL1 A;  2E4O A;  4DWB A;  4DXJ A;  1VG7 A;  4E9Z A;  3PYB A;  2J5C A;  3AQC B;  5IL3 A;  5DGS F;  3SDT A;  3MZV A;  4KQ5 A;  2PS8 A;  4MC8 A;  4RXC A;  5HN8 A;  3VJD A;  1RQJ A;  1V4K A;  1UBV A;  3SDV A;  3N5H F;  3WCH A;  1YHL A;  3OAB B;  4NG6 A;  3V1X A;  2J1P A;  2F9K F;  3SDR A;  3V1V A;  3KRA B;  2AET A;  3WEJ A;  1VG3 A;  2OPM A;  2F8Z F;  2ZCS A;  3KB9 A;  4JXN A;  4ZQ8 A;  2Z52 A;  4F6X A;  4LA5 A;  3WE9 A;  4PVY F;  3TC1 A;  3WEG A;  1WL2 A;  3WSB A;  1RQI A;  2FOR A;  3W7F A;  5B01 A;  3ZCD A;  3BNY A;  4GAX A;  2VF6 A;  3LK5 A;  3LGK A;  4LOB A;  2E8V A;  4H5C F;  3KRF A;  1YYR A;  1V4I A;  3WEI A;  4LPG F;  4LTV A;  5E8H A;  1YQ7 A;  2F94 F;  3VJB A;  4HD1 A;  3VJ9 A;  3ICM A;  2ONH A;  4QPF A;  1JFA A;  4KK2 A;  2E8W A;  1V4E A;  1WY0 A;  5ERO A;  4DHD A;  4KQS A;  5A0K A;  5KSX F;  4LFG A;  4NFK F;  5EAS A;  4RXD A;  2OPN A;  2E95 A;  3ZMB A;  5ERN A;  3BNX A;  5B0K A;  3WCD A;  4H5D F;  1DGP A;  2ONG A;  4P0W A;  3LDW A;  3M02 A;  5AHU B;  3N45 F;  2Z4Z A;  3P5R A;  5CG6 A;  4JZB A;  4JZX A;  5IMN A;  3LVS A;  1JFG A;  4H5E F;  3TFV A;  1N21 A;  5ILZ A;  1RTR A;  2OGD A;  5JA0 F;  5DGM F;  2Z78 A;  4DWG A;  4MC3 A;  2AZL A;  2EWG A;  2Q9Z A;  5B0J A;  3LMD A;  2Q9Y A;  2RAH A;  3ICN A;  2AEK A;  3P8R A;  1KIY A;  3TFP A;  2QIS A;  3S4J A;  3KRO A;  1DI1 A;  1HXG A;  1VG6 A;  3OAC B;  1YYU A;  3DYG A;  1VG4 A;  5ILD A;  3VJE A;  1HXC A;  3WJK A;  3WCC A;  4JYX A;  2H8O A;  4L2X F;  2Z4Y A;  2E8T A;  3WSA A;  5ILJ A;  4MC0 A;  4LUU A;  3M01 A;  5AYP A;  3LEE A;  3ICZ A;  1YHK A;  5B0I A;  3WCM A;  3SDQ A;  3MAV A;  5DJR F;  3VJA A;  5AEL A;  2ZEV A;  3ZOU A;  5JV1 F;  2PS7 A;  3G4D A;  1YJ4 A;  2OA6 A;  2Q58 A;  4P0X A;  5JUZ F;  3S9V A;  2Z7H A;  3EZ3 A;  5DJP F;  3OAB A;  3IBA A;  5H9D A;  3IPI A;  3ID0 A;  3N5J F;  4LZC A;  5IKA A;  3P41 A;  2E90 A;  5IMP A;  5IK6 A;  3TS7 A;  4EA2 A;  2AZJ A;  4JVJ F;  1N1Z A;  4OMH A;  1WL0 A;  4LIX A;  2P1C A;  3NF2 A;  3Q30 A;  5DJV F;  3QQV A;  3SDU A;  5EAU A;  3M9U A;  3Q1O A;  4LZ3 A;  4OKM A;  3RYE A;  4UMJ A;  4OMG A;  1KIZ A;  1FPS A;  5DW7 A;  1YYT A;  5E8K A;  5EAT A;  3WCG A;  2I19 A;  4LZ0 A;  3RYW A;  5DZ2 A;  5IM1 A;  3KRP A;  2Z4W A;  4LLT A;  4K10 A;  3N6K F;  5A0J A;  4E1E A;  3PH7 A;  3WJN A;  1YHM A;  3WCL A;  5B03 A;  4XQS F;  4N1Z F;  1YYQ A;  5IK9 A;  2E8X A;  1EZF A;  3WCA A;  1YV5 A;  2O1O A;  3KRC A;  5B0L A;  4GA3 A;  4KFA A;  4GP1 A;  3UCA A;  1UBY A;  2Z7I A;  4LLS A;  4XQT F;  4FJQ A;  5ILK A;  1HX9 A;  5JV2 F;  2E8U A;  2Z4V A;  3N1V F;  3LOM A;  4F6V A;  4LTZ A;  3WCJ A;  3WEK A;  3AQB B;  4DZW A;  5ILI A;  4WK5 A;  3LJI A;  4EA0 A;  4LFV F;  5A0I A;  5IMI A;  4GP2 A;  4OKZ A;  2J1O A;  4P0V A;  2AEL A;  4FP4 A;  1UBX A;  3DYF A;  3V66 A;  2F8C F;  3M0G A;  5ERM A;  3EFQ A;  4NFI F;  3LZ9 A;  3DYH A;  3KBK A;  3N0F A;  1PS1 A;  2PS6 A;  3ADZ A;  5C05 A;  4LXW A;  4E9U A;  3LSN A;  4JXY A;  2ZCO A;  3OAC A;  4RYP A;  3N0G A;  4KVI A;  3NPR A;  4RXE A;  3ZL6 A;  1UBW A;  4KKM A;  5IK0 A;  3N46 F;  4F62 A;  3VJ8 A;  2Z50 A;  4DEM F;  3N3L F;  4RNQ A;  4OGU A;  3CC9 A;  3OYR A;  1N22 A;  2Z4X A;  3NRI A;  5HN9 A;  2E91 A;  4Q23 A;  4NKF A;  3EGT A;  3M00 A;  1VG2 A;  3Q2Q A;  5IN8 A;  2E92 A;  2ZY1 A;  1N23 A;  2ZCQ A;  1HM4 A;  4KUX A;  4DI5 A;  1HXA A;  5DHK A;  1WKZ A;  3KRA A;  4KPD A;  3APZ A;  5I1U A;  1YYS A;  4LFE A;  3AE0 A;  1N20 A;  2ZCR A;  4LA6 A;  5ER8 A;  3TFN A;  2Q80 A;  4KWD A;  3WCB A;  5B0M A;  3N49 F;  4QXS F;  3N3D A;  3CKE A;  4NFJ F;  5DHI A;  3KRF B;  4N9U A;  3ICK A;  4NKE A;  3WCF A;  1ZW5 A;  3P8L A;  2DH4 A;  3N1W F;  3ACW A;  3VJC A;  5JV0 F;  2PS4 A;  5DIQ F;  3WCI A;  3ACX A;  5IVG A;  3PDE A;  3LLW A;  5IL8 A; 
#chains in the Genus database with same CATH homology
 3RBM A;  3CP6 A;  4KVW A;  4KPJ A;  2E93 A;  5E8L A;  2E94 A;  3KRP B;  3ZMC A;  3SAE A;  5IKH A;  3RMG A;  3LGZ B;  3WEF A;  4KQU A;  4NUA A;  3NPK A;  4EA1 A;  4KVY A;  4RXA A;  3QKC A;  1V4H A;  2F92 F;  5HNA A;  1N24 A;  1WL3 A;  2ZEU A;  3KRC B;  1WMW A;  3WCE A;  4KVD A;  5DGN F;  5B00 A;  1V4J A;  3P5P A;  3ACY A;  3AQ0 A;  3LG5 A;  5AFX A;  5CG5 A;  3Q2Z A;  4PVX F;  4XQR F;  3PYA A;  4LPH F;  5ILY A;  3WEH A;  2PS5 A;  3WJO A;  3PKO A;  5ILH A;  3KRO B;  3B7L A;  3ASX A;  3G4F A;  5HN7 A;  5B02 A;  2F7M F;  1HM7 A;  2AZK A;  2FTZ A;  1N1B A;  2F89 F;  3WC9 A;  1WL1 A;  2E4O A;  4DWB A;  4DXJ A;  1VG7 A;  4E9Z A;  3PYB A;  2J5C A;  3AQC B;  5IL3 A;  5DGS F;  3SDT A;  3MZV A;  4KQ5 A;  2PS8 A;  4MC8 A;  4RXC A;  5HN8 A;  3VJD A;  1RQJ A;  1V4K A;  1UBV A;  3SDV A;  3N5H F;  3WCH A;  1YHL A;  3OAB B;  4NG6 A;  3V1X A;  2J1P A;  2F9K F;  3SDR A;  3V1V A;  3KRA B;  2AET A;  3WEJ A;  1VG3 A;  2OPM A;  2F8Z F;  2ZCS A;  3KB9 A;  4JXN A;  4ZQ8 A;  2Z52 A;  4F6X A;  4LA5 A;  3WE9 A;  4PVY F;  3TC1 A;  3WEG A;  1WL2 A;  3WSB A;  1RQI A;  2FOR A;  3W7F A;  5B01 A;  3ZCD A;  3BNY A;  4GAX A;  2VF6 A;  3LK5 A;  3LGK A;  4LOB A;  2E8V A;  4H5C F;  3KRF A;  1YYR A;  1V4I A;  3WEI A;  4LPG F;  4LTV A;  5E8H A;  1YQ7 A;  2F94 F;  3VJB A;  4HD1 A;  3VJ9 A;  3ICM A;  2ONH A;  4QPF A;  1JFA A;  4KK2 A;  2E8W A;  1V4E A;  1WY0 A;  5ERO A;  4DHD A;  4KQS A;  5A0K A;  5KSX F;  4LFG A;  4NFK F;  5EAS A;  4RXD A;  2OPN A;  2E95 A;  3ZMB A;  5ERN A;  3BNX A;  5B0K A;  3WCD A;  4H5D F;  1DGP A;  2ONG A;  4P0W A;  3LDW A;  3M02 A;  5AHU B;  3N45 F;  2Z4Z A;  3P5R A;  5CG6 A;  4JZB A;  4JZX A;  5IMN A;  3LVS A;  1JFG A;  4H5E F;  3TFV A;  1N21 A;  5ILZ A;  1RTR A;  2OGD A;  5JA0 F;  5DGM F;  2Z78 A;  4DWG A;  4MC3 A;  2AZL A;  2EWG A;  2Q9Z A;  5B0J A;  3LMD A;  2Q9Y A;  2RAH A;  3ICN A;  2AEK A;  3P8R A;  1KIY A;  3TFP A;  2QIS A;  3S4J A;  3KRO A;  1DI1 A;  1HXG A;  1VG6 A;  3OAC B;  1YYU A;  3DYG A;  1VG4 A;  5ILD A;  3VJE A;  1HXC A;  3WJK A;  3WCC A;  4JYX A;  2H8O A;  4L2X F;  2Z4Y A;  2E8T A;  3WSA A;  5ILJ A;  4MC0 A;  4LUU A;  3M01 A;  5AYP A;  3LEE A;  3ICZ A;  1YHK A;  5B0I A;  3WCM A;  3SDQ A;  3MAV A;  5DJR F;  3VJA A;  5AEL A;  2ZEV A;  3ZOU A;  5JV1 F;  2PS7 A;  3G4D A;  1YJ4 A;  2OA6 A;  2Q58 A;  4P0X A;  5JUZ F;  3S9V A;  2Z7H A;  3EZ3 A;  5DJP F;  3OAB A;  3IBA A;  5H9D A;  3IPI A;  3ID0 A;  3N5J F;  4LZC A;  5IKA A;  3P41 A;  2E90 A;  5IMP A;  5IK6 A;  3TS7 A;  4EA2 A;  2AZJ A;  4JVJ F;  1N1Z A;  4OMH A;  1WL0 A;  4LIX A;  2P1C A;  3NF2 A;  3Q30 A;  5DJV F;  3QQV A;  3SDU A;  5EAU A;  3M9U A;  3Q1O A;  4LZ3 A;  4OKM A;  3RYE A;  4UMJ A;  4OMG A;  1KIZ A;  1FPS A;  5DW7 A;  1YYT A;  5E8K A;  5EAT A;  3WCG A;  2I19 A;  4LZ0 A;  3RYW A;  5DZ2 A;  5IM1 A;  3KRP A;  2Z4W A;  4LLT A;  4K10 A;  3N6K F;  5A0J A;  4E1E A;  3PH7 A;  3WJN A;  1YHM A;  3WCL A;  5B03 A;  4XQS F;  4N1Z F;  1YYQ A;  5IK9 A;  2E8X A;  1EZF A;  3WCA A;  1YV5 A;  2O1O A;  3KRC A;  5B0L A;  4GA3 A;  4KFA A;  4GP1 A;  3UCA A;  1UBY A;  2Z7I A;  4LLS A;  4XQT F;  4FJQ A;  5ILK A;  1HX9 A;  5JV2 F;  2E8U A;  2Z4V A;  3N1V F;  3LOM A;  4F6V A;  4LTZ A;  3WCJ A;  3WEK A;  3AQB B;  4DZW A;  5ILI A;  4WK5 A;  3LJI A;  4EA0 A;  4LFV F;  5A0I A;  5IMI A;  4GP2 A;  4OKZ A;  2J1O A;  4P0V A;  2AEL A;  4FP4 A;  1UBX A;  3DYF A;  3V66 A;  2F8C F;  3M0G A;  5ERM A;  3EFQ A;  4NFI F;  3LZ9 A;  3DYH A;  3KBK A;  3N0F A;  1PS1 A;  2PS6 A;  3ADZ A;  5C05 A;  4LXW A;  4E9U A;  3LSN A;  4JXY A;  2ZCO A;  3OAC A;  4RYP A;  3N0G A;  4KVI A;  3NPR A;  4RXE A;  3ZL6 A;  1UBW A;  4KKM A;  5IK0 A;  3N46 F;  4F62 A;  3VJ8 A;  2Z50 A;  4DEM F;  3N3L F;  4RNQ A;  4OGU A;  3CC9 A;  3OYR A;  1N22 A;  2Z4X A;  3NRI A;  5HN9 A;  2E91 A;  4Q23 A;  4NKF A;  3EGT A;  3M00 A;  1VG2 A;  3Q2Q A;  5IN8 A;  2E92 A;  2ZY1 A;  1N23 A;  2ZCQ A;  1HM4 A;  4KUX A;  4DI5 A;  1HXA A;  5DHK A;  1WKZ A;  3KRA A;  4KPD A;  3APZ A;  5I1U A;  1YYS A;  4LFE A;  3AE0 A;  1N20 A;  2ZCR A;  4LA6 A;  5ER8 A;  3TFN A;  2Q80 A;  4KWD A;  3WCB A;  5B0M A;  3N49 F;  4QXS F;  3N3D A;  3CKE A;  4NFJ F;  5DHI A;  3KRF B;  4N9U A;  3ICK A;  4NKE A;  3WCF A;  1ZW5 A;  3P8L A;  2DH4 A;  3N1W F;  3ACW A;  3VJC A;  5JV0 F;  2PS4 A;  5DIQ F;  3WCI A;  3ACX A;  5IVG A;  3PDE A;  3LLW A;  5IL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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