2Z4VA

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ggpp (inhibitory site)
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
336
structure length
314
Chain Sequence
NKMEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSHGHSLVPFINLLGIIYQIRDDYLNLKDFQFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPELLYIIDHLSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Geranylgeranyl pyrophosphate synthetase
total genus 131
structure length 314
sequence length 336
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2z4vA00
3LEEA 2FTZA 4LLSA 4DEMF 4GA3A 2ONHA 5IM1A 3TFNA 3MZVA 3VJAA 3NF2A 5CG5A 4LZ3A 1V4JA 5DGSF 3UCAA 3G4DA 4NFJF 2F92F 3LJIA 2Q58A 4LIXA 2H8OA 4OKZA 4P0WA 3S4JA 1HXGA 2Z78A 4JVJF 2E8XA 2PS5A 3Q2QA 4FP4A 4LFEA 3KRPB 3LGKA 4NKEA 3BNXA 2ONGA 4F6XA 4F62A 3B7LA 3WEJA 4H5DF 4XQTF 3RYEA 4PVYF 2Q9ZA 2Z7IA 5DW7A 1UBWA 3NPKA 1WMWA 4K10A 1YHLA 2E94A 1WY0A 3AE0A 3OABB 3M0GA 3G4FA 5IK0A 5JA0F 5JV1F 3KRCB 5DJVF 5DHIA 3IPIA 4MC3A 1KIYA 2ZEUA 2PS7A 5EROA 3ICKA 1HX9A 1HM7A 4E1EA 2E4OA 2QISA 5I1UA 3LLWA 5HNAA 4LZ0A 3N45F 2Z52A 4LXWA 1N1ZA 3KRAB 3N5HF 2E95A 3N49F 1VG6A 1YJ4A 2J1PA 3NPRA 5B03A 3PDEA 1VG4A 4RYPA 2Q9YA 3RBMA 3TFPA 4N9UA 4OKMA 3ICMA 3M00A 5AYPA 2AETA 3N3DA 2VF6A 5IL8A 5ILDA 3N0FA 3VJCA 3N46F 5DZ2A 4UMJA 4JZBA 3KB9A 3P5RA 4NUAA 4Q23A 5DHKA 2O1OA 3N6KF 5B01A 5E8HA 4OMGA 3P5PA 4DWGA 3CKEA 3ICZA 3ICNA 4L2XF 4LTZA 5ER8A 1KIZA 2Z4VA 3WEHA 3NRIA 3KRPA 3M02A 3P8LA 2EWGA 1PS1A 2AELA 1V4IA 4RXCA 2F8ZF 4MC0A 2E92A 3SDQA 5IMNA 2OA6A 5EAUA 3DYFA 3MAVA 4JXYA 1YHMA 1YYQA 4LUUA 3N3LF 3EGTA 1JFGA 4PVXF 3SDUA 2Q80A 3KRCA 2ZCOA 2PS6A 2E8VA 3ZMCA 4KUXA 3V66A 3Q1OA 1HM4A 4KK2A 4KPJA 3LVSA 3TC1A 2J5CA 4DXJA 4KWDA 4KVIA 2E90A 5A0JA 3Q2ZA 3WEGA 3OACB 3ACWA 4RXEA 3KRAA 4KQSA 5ILKA 4QXSF 4HD1A 4KPDA 3IBAA 4JZXA 4QPFA 1WKZA 1DGPA 3BNYA 3VJEA 2ZCSA 5H9DA 4RXDA 2F89F 3WCAA 1DI1A 1N22A 2F7MF 4E9ZA 4KKMA 3ASXA 2F94F 1HXCA 2AEKA 5B0MA 3N1VF 2DH4A 1YV5A 4XQSF 3LK5A 1EZFA 3WJKA 3KRFB 3WEIA 3ZCDA 3SAEA 1VG7A 1RTRA 3WCLA 5C05A 1VG3A 1WL2A 4EA0A 5DIQF 5A0IA 5B0JA 4DZWA 3M9UA 2OGDA 3TFVA 3PYBA 3AQCB 3SDTA 4KVWA 5JV2F 2Z7HA 4EA1A 3PH7A 4NFKF 2OPNA 5AHUB 5IKHA 3RMGA 3ZMBA 2Z4YA 3LOMA 4JXNA 3P41A 2E91A 4GAXA 4KFAA 4KQ5A 2ZCQA 1HXAA 1N20A 3LDWA 5JUZF 4XQRF 2OPMA 3QKCA 3SDVA 4H5CF 3WC9A 4ZQ8A 2F9KF 3Q30A 4LFGA 4NG6A 3KROB 4H5EF 2J1OA 5DGMF 3W7FA 3S9VA 3LMDA 4WK5A 3V1VA 3TS7A 4LZCA 1YHKA 3LGZB 1V4HA 3WEKA 5AELA 2ZCRA 1RQIA 3WCJA 1YYTA 3OACA 3WCMA 2I19A 4KQUA 1UBXA 4LLTA 2AZLA 3WCEA 4LPHF 3WJNA 3OABA 4LTVA 1V4EA 3PYAA 5ILJA 5DGNF 3WJOA 2PS8A 2RAHA 5DJPF 1ZW5A 3QQVA 2Z4ZA 2Z4XA 4EA2A 3AQ0A 5KSXF 4FJQA 5HN7A 3EZ3A 4E9UA 5IK9A 2E93A 4GP1A 3KRFA 3SDRA 5DJRF 3WSAA 4KVYA 3DYHA 3P8RA 1WL1A 2AZJA 2E8TA 5EASA 3WCDA 5B02A 2F8CF 1N23A 3ZL6A 5E8KA 5ERMA 1YQ7A 5ILHA 1N24A 3AQBB 4LOBA 5ERNA 3DYGA 5HN9A 3ID0A 4DHDA 5B0IA 1N21A 5IK6A 3VJ8A 2ZY1A 3WCFA 4GP2A 4P0XA 3N5JF 1YYRA 4RXAA 4NFIF 4LPGF 5IL3A 1YYSA 3WCCA 3KROA 4NKFA 3WCBA 3WCGA 5EATA 3WCHA 1V4KA 2ZEVA 1VG2A 1UBVA 4LA5A 1WL0A 3WE9A 3WSBA 5IMPA 5ILYA 3VJBA 3ADZA 4N1ZF 2E8UA 2Z50A 5IKAA 3ACXA 3N0GA 2Z4WA 3ACYA 4RNQA 3OYRA 1WL3A 4DI5A 1FPSA 3M01A 4MC8A 5CG6A 3LSNA 1RQJA 5ILZA 3APZA 3LG5A 5AFXA 5B0LA 3EFQA 3V1XA 1N1BA 4LFVF 5E8LA 5A0KA 5B00A 4OMHA 3KBKA 2P1CA 3WCIA 5JV0F 5IN8A 3LZ9A 4KVDA 3PKOA 3VJDA 2FORA 1YYUA 1JFAA 2E8WA 3WEFA 1UBYA 3VJ9A 5B0KA 3N1WF 4P0VA 3CP6A 5HN8A 5IVGA 5IMIA 3ZOUA 4OGUA 4DWBA 4F6VA 3CC9A 5ILIA 2PS4A 4JYXA 3RYWA 4LA6A 2AZKA
chains in the Genus database with same CATH superfamily
3LEEA 2FTZA 4LLSA 4DEMF 4GA3A 2ONHA 5IM1A 3TFNA 3MZVA 3VJAA 3NF2A 5CG5A 4LZ3A 1V4JA 5DGSF 3UCAA 3G4DA 4NFJF 2F92F 3LJIA 2Q58A 4LIXA 2H8OA 4OKZA 4P0WA 3S4JA 1HXGA 2Z78A 4JVJF 2E8XA 2PS5A 3Q2QA 4FP4A 4LFEA 3KRPB 3LGKA 4NKEA 3BNXA 2ONGA 4F6XA 4F62A 3B7LA 3WEJA 4H5DF 4XQTF 3RYEA 4PVYF 2Q9ZA 2Z7IA 5DW7A 1UBWA 3NPKA 1WMWA 4K10A 1YHLA 2E94A 1WY0A 3AE0A 3OABB 3M0GA 3G4FA 5IK0A 5JA0F 5JV1F 3KRCB 5DJVF 5DHIA 3IPIA 4MC3A 1KIYA 2ZEUA 2PS7A 5EROA 3ICKA 1HX9A 1HM7A 4E1EA 2E4OA 2QISA 5I1UA 3LLWA 5HNAA 4LZ0A 3N45F 2Z52A 4LXWA 1N1ZA 3KRAB 3N5HF 2E95A 3N49F 1VG6A 1YJ4A 2J1PA 3NPRA 5B03A 3PDEA 1VG4A 4RYPA 2Q9YA 3RBMA 3TFPA 4N9UA 4OKMA 3ICMA 3M00A 5AYPA 2AETA 3N3DA 2VF6A 5IL8A 5ILDA 3N0FA 3VJCA 3N46F 5DZ2A 4UMJA 4JZBA 3KB9A 3P5RA 4NUAA 4Q23A 5DHKA 2O1OA 3N6KF 5B01A 5E8HA 4OMGA 3P5PA 4DWGA 3CKEA 3ICZA 3ICNA 4L2XF 4LTZA 5ER8A 1KIZA 2Z4VA 3WEHA 3NRIA 3KRPA 3M02A 3P8LA 2EWGA 1PS1A 2AELA 1V4IA 4RXCA 2F8ZF 4MC0A 2E92A 3SDQA 5IMNA 2OA6A 5EAUA 3DYFA 3MAVA 4JXYA 1YHMA 1YYQA 4LUUA 3N3LF 3EGTA 1JFGA 4PVXF 3SDUA 2Q80A 3KRCA 2ZCOA 2PS6A 2E8VA 3ZMCA 4KUXA 3V66A 3Q1OA 1HM4A 4KK2A 4KPJA 3LVSA 3TC1A 2J5CA 4DXJA 4KWDA 4KVIA 2E90A 5A0JA 3Q2ZA 3WEGA 3OACB 3ACWA 4RXEA 3KRAA 4KQSA 5ILKA 4QXSF 4HD1A 4KPDA 3IBAA 4JZXA 4QPFA 1WKZA 1DGPA 3BNYA 3VJEA 2ZCSA 5H9DA 4RXDA 2F89F 3WCAA 1DI1A 1N22A 2F7MF 4E9ZA 4KKMA 3ASXA 2F94F 1HXCA 2AEKA 5B0MA 3N1VF 2DH4A 1YV5A 4XQSF 3LK5A 1EZFA 3WJKA 3KRFB 3WEIA 3ZCDA 3SAEA 1VG7A 1RTRA 3WCLA 5C05A 1VG3A 1WL2A 4EA0A 5DIQF 5A0IA 5B0JA 4DZWA 3M9UA 2OGDA 3TFVA 3PYBA 3AQCB 3SDTA 4KVWA 5JV2F 2Z7HA 4EA1A 3PH7A 4NFKF 2OPNA 5AHUB 5IKHA 3RMGA 3ZMBA 2Z4YA 3LOMA 4JXNA 3P41A 2E91A 4GAXA 4KFAA 4KQ5A 2ZCQA 1HXAA 1N20A 3LDWA 5JUZF 4XQRF 2OPMA 3QKCA 3SDVA 4H5CF 3WC9A 4ZQ8A 2F9KF 3Q30A 4LFGA 4NG6A 3KROB 4H5EF 2J1OA 5DGMF 3W7FA 3S9VA 3LMDA 4WK5A 3V1VA 3TS7A 4LZCA 1YHKA 3LGZB 1V4HA 3WEKA 5AELA 2ZCRA 1RQIA 3WCJA 1YYTA 3OACA 3WCMA 2I19A 4KQUA 1UBXA 4LLTA 2AZLA 3WCEA 4LPHF 3WJNA 3OABA 4LTVA 1V4EA 3PYAA 5ILJA 5DGNF 3WJOA 2PS8A 2RAHA 5DJPF 1ZW5A 3QQVA 2Z4ZA 2Z4XA 4EA2A 3AQ0A 5KSXF 4FJQA 5HN7A 3EZ3A 4E9UA 5IK9A 2E93A 4GP1A 3KRFA 3SDRA 5DJRF 3WSAA 4KVYA 3DYHA 3P8RA 1WL1A 2AZJA 2E8TA 5EASA 3WCDA 5B02A 2F8CF 1N23A 3ZL6A 5E8KA 5ERMA 1YQ7A 5ILHA 1N24A 3AQBB 4LOBA 5ERNA 3DYGA 5HN9A 3ID0A 4DHDA 5B0IA 1N21A 5IK6A 3VJ8A 2ZY1A 3WCFA 4GP2A 4P0XA 3N5JF 1YYRA 4RXAA 4NFIF 4LPGF 5IL3A 1YYSA 3WCCA 3KROA 4NKFA 3WCBA 3WCGA 5EATA 3WCHA 1V4KA 2ZEVA 1VG2A 1UBVA 4LA5A 1WL0A 3WE9A 3WSBA 5IMPA 5ILYA 3VJBA 3ADZA 4N1ZF 2E8UA 2Z50A 5IKAA 3ACXA 3N0GA 2Z4WA 3ACYA 4RNQA 3OYRA 1WL3A 4DI5A 1FPSA 3M01A 4MC8A 5CG6A 3LSNA 1RQJA 5ILZA 3APZA 3LG5A 5AFXA 5B0LA 3EFQA 3V1XA 1N1BA 4LFVF 5E8LA 5A0KA 5B00A 4OMHA 3KBKA 2P1CA 3WCIA 5JV0F 5IN8A 3LZ9A 4KVDA 3PKOA 3VJDA 2FORA 1YYUA 1JFAA 2E8WA 3WEFA 1UBYA 3VJ9A 5B0KA 3N1WF 4P0VA 3CP6A 5HN8A 5IVGA 5IMIA 3ZOUA 4OGUA 4DWBA 4F6VA 3CC9A 5ILIA 2PS4A 4JYXA 3RYWA 4LA6A 2AZKA
chains in the Genus database with same CATH topology
3LEEA 2FTZA 4LLSA 4DEMF 4GA3A 2ONHA 5IM1A 3TFNA 3MZVA 3VJAA 3NF2A 5CG5A 4LZ3A 1V4JA 5DGSF 3UCAA 3G4DA 4NFJF 2F92F 3LJIA 2Q58A 4LIXA 2H8OA 4OKZA 4P0WA 3S4JA 1HXGA 2Z78A 4JVJF 2E8XA 2PS5A 3Q2QA 4FP4A 4LFEA 3KRPB 3LGKA 4NKEA 3BNXA 2ONGA 4F6XA 4F62A 3B7LA 3WEJA 4H5DF 4XQTF 3RYEA 4PVYF 2Q9ZA 2Z7IA 5DW7A 1UBWA 3NPKA 1WMWA 4K10A 1YHLA 2E94A 1WY0A 3AE0A 3OABB 3M0GA 3G4FA 5IK0A 5JA0F 5JV1F 3KRCB 5DJVF 5DHIA 3IPIA 4MC3A 1KIYA 2ZEUA 2PS7A 5EROA 3ICKA 1HX9A 1HM7A 4E1EA 2E4OA 2QISA 5I1UA 3LLWA 5HNAA 4LZ0A 3N45F 2Z52A 4LXWA 1N1ZA 3KRAB 3N5HF 2E95A 3N49F 1VG6A 1YJ4A 2J1PA 3NPRA 5B03A 3PDEA 1VG4A 4RYPA 2Q9YA 3RBMA 3TFPA 4N9UA 4OKMA 3ICMA 3M00A 5AYPA 2AETA 3N3DA 2VF6A 5IL8A 5ILDA 3N0FA 3VJCA 3N46F 5DZ2A 4UMJA 4JZBA 3KB9A 3P5RA 4NUAA 4Q23A 5DHKA 2O1OA 3N6KF 5B01A 5E8HA 4OMGA 3P5PA 4DWGA 3CKEA 3ICZA 3ICNA 4L2XF 4LTZA 5ER8A 1KIZA 2Z4VA 3WEHA 3NRIA 3KRPA 3M02A 3P8LA 2EWGA 1PS1A 2AELA 1V4IA 4RXCA 2F8ZF 4MC0A 2E92A 3SDQA 5IMNA 2OA6A 5EAUA 3DYFA 3MAVA 4JXYA 1YHMA 1YYQA 4LUUA 3N3LF 3EGTA 1JFGA 4PVXF 3SDUA 2Q80A 3KRCA 2ZCOA 2PS6A 2E8VA 3ZMCA 4KUXA 3V66A 3Q1OA 1HM4A 4KK2A 4KPJA 3LVSA 3TC1A 2J5CA 4DXJA 4KWDA 4KVIA 2E90A 5A0JA 3Q2ZA 3WEGA 3OACB 3ACWA 4RXEA 3KRAA 4KQSA 5ILKA 4QXSF 4HD1A 4KPDA 3IBAA 4JZXA 4QPFA 1WKZA 1DGPA 3BNYA 3VJEA 2ZCSA 5H9DA 4RXDA 2F89F 3WCAA 1DI1A 1N22A 2F7MF 4E9ZA 4KKMA 3ASXA 2F94F 1HXCA 2AEKA 5B0MA 3N1VF 2DH4A 1YV5A 4XQSF 3LK5A 1EZFA 3WJKA 3KRFB 3WEIA 3ZCDA 3SAEA 1VG7A 1RTRA 3WCLA 5C05A 1VG3A 1WL2A 4EA0A 5DIQF 5A0IA 5B0JA 4DZWA 3M9UA 2OGDA 3TFVA 3PYBA 3AQCB 3SDTA 4KVWA 5JV2F 2Z7HA 4EA1A 3PH7A 4NFKF 2OPNA 5AHUB 5IKHA 3RMGA 3ZMBA 2Z4YA 3LOMA 4JXNA 3P41A 2E91A 4GAXA 4KFAA 4KQ5A 2ZCQA 1HXAA 1N20A 3LDWA 5JUZF 4XQRF 2OPMA 3QKCA 3SDVA 4H5CF 3WC9A 4ZQ8A 2F9KF 3Q30A 4LFGA 4NG6A 3KROB 4H5EF 2J1OA 5DGMF 3W7FA 3S9VA 3LMDA 4WK5A 3V1VA 3TS7A 4LZCA 1YHKA 3LGZB 1V4HA 3WEKA 5AELA 2ZCRA 1RQIA 3WCJA 1YYTA 3OACA 3WCMA 2I19A 4KQUA 1UBXA 4LLTA 2AZLA 3WCEA 4LPHF 3WJNA 3OABA 4LTVA 1V4EA 3PYAA 5ILJA 5DGNF 3WJOA 2PS8A 2RAHA 5DJPF 1ZW5A 3QQVA 2Z4ZA 2Z4XA 4EA2A 3AQ0A 5KSXF 4FJQA 5HN7A 3EZ3A 4E9UA 5IK9A 2E93A 4GP1A 3KRFA 3SDRA 5DJRF 3WSAA 4KVYA 3DYHA 3P8RA 1WL1A 2AZJA 2E8TA 5EASA 3WCDA 5B02A 2F8CF 1N23A 3ZL6A 5E8KA 5ERMA 1YQ7A 5ILHA 1N24A 3AQBB 4LOBA 5ERNA 3DYGA 5HN9A 3ID0A 4DHDA 5B0IA 1N21A 5IK6A 3VJ8A 2ZY1A 3WCFA 4GP2A 4P0XA 3N5JF 1YYRA 4RXAA 4NFIF 4LPGF 5IL3A 1YYSA 3WCCA 3KROA 4NKFA 3WCBA 3WCGA 5EATA 3WCHA 1V4KA 2ZEVA 1VG2A 1UBVA 4LA5A 1WL0A 3WE9A 3WSBA 5IMPA 5ILYA 3VJBA 3ADZA 4N1ZF 2E8UA 2Z50A 5IKAA 3ACXA 3N0GA 2Z4WA 3ACYA 4RNQA 3OYRA 1WL3A 4DI5A 1FPSA 3M01A 4MC8A 5CG6A 3LSNA 1RQJA 5ILZA 3APZA 3LG5A 5AFXA 5B0LA 3EFQA 3V1XA 1N1BA 4LFVF 5E8LA 5A0KA 5B00A 4OMHA 3KBKA 2P1CA 3WCIA 5JV0F 5IN8A 3LZ9A 4KVDA 3PKOA 3VJDA 2FORA 1YYUA 1JFAA 2E8WA 3WEFA 1UBYA 3VJ9A 5B0KA 3N1WF 4P0VA 3CP6A 5HN8A 5IVGA 5IMIA 3ZOUA 4OGUA 4DWBA 4F6VA 3CC9A 5ILIA 2PS4A 4JYXA 3RYWA 4LA6A 2AZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LEE A;  2FTZ A;  4LLS A;  4DEM F;  4GA3 A;  2ONH A;  5IM1 A;  3TFN A;  3MZV A;  3VJA A;  3NF2 A;  5CG5 A;  4LZ3 A;  1V4J A;  5DGS F;  3UCA A;  3G4D A;  4NFJ F;  2F92 F;  3LJI A;  2Q58 A;  4LIX A;  2H8O A;  4OKZ A;  4P0W A;  3S4J A;  1HXG A;  2Z78 A;  4JVJ F;  2E8X A;  2PS5 A;  3Q2Q A;  4FP4 A;  4LFE A;  3KRP B;  3LGK A;  4NKE A;  3BNX A;  2ONG A;  4F6X A;  4F62 A;  3B7L A;  3WEJ A;  4H5D F;  4XQT F;  3RYE A;  4PVY F;  2Q9Z A;  2Z7I A;  5DW7 A;  1UBW A;  3NPK A;  1WMW A;  4K10 A;  1YHL A;  2E94 A;  1WY0 A;  3AE0 A;  3OAB B;  3M0G A;  3G4F A;  5IK0 A;  5JA0 F;  5JV1 F;  3KRC B;  5DJV F;  5DHI A;  3IPI A;  4MC3 A;  1KIY A;  2ZEU A;  2PS7 A;  5ERO A;  3ICK A;  1HX9 A;  1HM7 A;  4E1E A;  2E4O A;  2QIS A;  5I1U A;  3LLW A;  5HNA A;  4LZ0 A;  3N45 F;  2Z52 A;  4LXW A;  1N1Z A;  3KRA B;  3N5H F;  2E95 A;  3N49 F;  1VG6 A;  1YJ4 A;  2J1P A;  3NPR A;  5B03 A;  3PDE A;  1VG4 A;  4RYP A;  2Q9Y A;  3RBM A;  3TFP A;  4N9U A;  4OKM A;  3ICM A;  3M00 A;  5AYP A;  2AET A;  3N3D A;  2VF6 A;  5IL8 A;  5ILD A;  3N0F A;  3VJC A;  3N46 F;  5DZ2 A;  4UMJ A;  4JZB A;  3KB9 A;  3P5R A;  4NUA A;  4Q23 A;  5DHK A;  2O1O A;  3N6K F;  5B01 A;  5E8H A;  4OMG A;  3P5P A;  4DWG A;  3CKE A;  3ICZ A;  3ICN A;  4L2X F;  4LTZ A;  5ER8 A;  1KIZ A;  2Z4V A;  3WEH A;  3NRI A;  3KRP A;  3M02 A;  3P8L A;  2EWG A;  1PS1 A;  2AEL A;  1V4I A;  4RXC A;  2F8Z F;  4MC0 A;  2E92 A;  3SDQ A;  5IMN A;  2OA6 A;  5EAU A;  3DYF A;  3MAV A;  4JXY A;  1YHM A;  1YYQ A;  4LUU A;  3N3L F;  3EGT A;  1JFG A;  4PVX F;  3SDU A;  2Q80 A;  3KRC A;  2ZCO A;  2PS6 A;  2E8V A;  3ZMC A;  4KUX A;  3V66 A;  3Q1O A;  1HM4 A;  4KK2 A;  4KPJ A;  3LVS A;  3TC1 A;  2J5C A;  4DXJ A;  4KWD A;  4KVI A;  2E90 A;  5A0J A;  3Q2Z A;  3WEG A;  3OAC B;  3ACW A;  4RXE A;  3KRA A;  4KQS A;  5ILK A;  4QXS F;  4HD1 A;  4KPD A;  3IBA A;  4JZX A;  4QPF A;  1WKZ A;  1DGP A;  3BNY A;  3VJE A;  2ZCS A;  5H9D A;  4RXD A;  2F89 F;  3WCA A;  1DI1 A;  1N22 A;  2F7M F;  4E9Z A;  4KKM A;  3ASX A;  2F94 F;  1HXC A;  2AEK A;  5B0M A;  3N1V F;  2DH4 A;  1YV5 A;  4XQS F;  3LK5 A;  1EZF A;  3WJK A;  3KRF B;  3WEI A;  3ZCD A;  3SAE A;  1VG7 A;  1RTR A;  3WCL A;  5C05 A;  1VG3 A;  1WL2 A;  4EA0 A;  5DIQ F;  5A0I A;  5B0J A;  4DZW A;  3M9U A;  2OGD A;  3TFV A;  3PYB A;  3AQC B;  3SDT A;  4KVW A;  5JV2 F;  2Z7H A;  4EA1 A;  3PH7 A;  4NFK F;  2OPN A;  5AHU B;  5IKH A;  3RMG A;  3ZMB A;  2Z4Y A;  3LOM A;  4JXN A;  3P41 A;  2E91 A;  4GAX A;  4KFA A;  4KQ5 A;  2ZCQ A;  1HXA A;  1N20 A;  3LDW A;  5JUZ F;  4XQR F;  2OPM A;  3QKC A;  3SDV A;  4H5C F;  3WC9 A;  4ZQ8 A;  2F9K F;  3Q30 A;  4LFG A;  4NG6 A;  3KRO B;  4H5E F;  2J1O A;  5DGM F;  3W7F A;  3S9V A;  3LMD A;  4WK5 A;  3V1V A;  3TS7 A;  4LZC A;  1YHK A;  3LGZ B;  1V4H A;  3WEK A;  5AEL A;  2ZCR A;  1RQI A;  3WCJ A;  1YYT A;  3OAC A;  3WCM A;  2I19 A;  4KQU A;  1UBX A;  4LLT A;  2AZL A;  3WCE A;  4LPH F;  3WJN A;  3OAB A;  4LTV A;  1V4E A;  3PYA A;  5ILJ A;  5DGN F;  3WJO A;  2PS8 A;  2RAH A;  5DJP F;  1ZW5 A;  3QQV A;  2Z4Z A;  2Z4X A;  4EA2 A;  3AQ0 A;  5KSX F;  4FJQ A;  5HN7 A;  3EZ3 A;  4E9U A;  5IK9 A;  2E93 A;  4GP1 A;  3KRF A;  3SDR A;  5DJR F;  3WSA A;  4KVY A;  3DYH A;  3P8R A;  1WL1 A;  2AZJ A;  2E8T A;  5EAS A;  3WCD A;  5B02 A;  2F8C F;  1N23 A;  3ZL6 A;  5E8K A;  5ERM A;  1YQ7 A;  5ILH A;  1N24 A;  3AQB B;  4LOB A;  5ERN A;  3DYG A;  5HN9 A;  3ID0 A;  4DHD A;  5B0I A;  1N21 A;  5IK6 A;  3VJ8 A;  2ZY1 A;  3WCF A;  4GP2 A;  4P0X A;  3N5J F;  1YYR A;  4RXA A;  4NFI F;  4LPG F;  5IL3 A;  1YYS A;  3WCC A;  3KRO A;  4NKF A;  3WCB A;  3WCG A;  5EAT A;  3WCH A;  1V4K A;  2ZEV A;  1VG2 A;  1UBV A;  4LA5 A;  1WL0 A;  3WE9 A;  3WSB A;  5IMP A;  5ILY A;  3VJB A;  3ADZ A;  4N1Z F;  2E8U A;  2Z50 A;  5IKA A;  3ACX A;  3N0G A;  2Z4W A;  3ACY A;  4RNQ A;  3OYR A;  1WL3 A;  4DI5 A;  1FPS A;  3M01 A;  4MC8 A;  5CG6 A;  3LSN A;  1RQJ A;  5ILZ A;  3APZ A;  3LG5 A;  5AFX A;  5B0L A;  3EFQ A;  3V1X A;  1N1B A;  4LFV F;  5E8L A;  5A0K A;  5B00 A;  4OMH A;  3KBK A;  2P1C A;  3WCI A;  5JV0 F;  5IN8 A;  3LZ9 A;  4KVD A;  3PKO A;  3VJD A;  2FOR A;  1YYU A;  1JFA A;  2E8W A;  3WEF A;  1UBY A;  3VJ9 A;  5B0K A;  3N1W F;  4P0V A;  3CP6 A;  5HN8 A;  5IVG A;  5IMI A;  3ZOU A;  4OGU A;  4DWB A;  4F6V A;  3CC9 A;  5ILI A;  2PS4 A;  4JYX A;  3RYW A;  4LA6 A;  2AZK A; 
#chains in the Genus database with same CATH topology
 3LEE A;  2FTZ A;  4LLS A;  4DEM F;  4GA3 A;  2ONH A;  5IM1 A;  3TFN A;  3MZV A;  3VJA A;  3NF2 A;  5CG5 A;  4LZ3 A;  1V4J A;  5DGS F;  3UCA A;  3G4D A;  4NFJ F;  2F92 F;  3LJI A;  2Q58 A;  4LIX A;  2H8O A;  4OKZ A;  4P0W A;  3S4J A;  1HXG A;  2Z78 A;  4JVJ F;  2E8X A;  2PS5 A;  3Q2Q A;  4FP4 A;  4LFE A;  3KRP B;  3LGK A;  4NKE A;  3BNX A;  2ONG A;  4F6X A;  4F62 A;  3B7L A;  3WEJ A;  4H5D F;  4XQT F;  3RYE A;  4PVY F;  2Q9Z A;  2Z7I A;  5DW7 A;  1UBW A;  3NPK A;  1WMW A;  4K10 A;  1YHL A;  2E94 A;  1WY0 A;  3AE0 A;  3OAB B;  3M0G A;  3G4F A;  5IK0 A;  5JA0 F;  5JV1 F;  3KRC B;  5DJV F;  5DHI A;  3IPI A;  4MC3 A;  1KIY A;  2ZEU A;  2PS7 A;  5ERO A;  3ICK A;  1HX9 A;  1HM7 A;  4E1E A;  2E4O A;  2QIS A;  5I1U A;  3LLW A;  5HNA A;  4LZ0 A;  3N45 F;  2Z52 A;  4LXW A;  1N1Z A;  3KRA B;  3N5H F;  2E95 A;  3N49 F;  1VG6 A;  1YJ4 A;  2J1P A;  3NPR A;  5B03 A;  3PDE A;  1VG4 A;  4RYP A;  2Q9Y A;  3RBM A;  3TFP A;  4N9U A;  4OKM A;  3ICM A;  3M00 A;  5AYP A;  2AET A;  3N3D A;  2VF6 A;  5IL8 A;  5ILD A;  3N0F A;  3VJC A;  3N46 F;  5DZ2 A;  4UMJ A;  4JZB A;  3KB9 A;  3P5R A;  4NUA A;  4Q23 A;  5DHK A;  2O1O A;  3N6K F;  5B01 A;  5E8H A;  4OMG A;  3P5P A;  4DWG A;  3CKE A;  3ICZ A;  3ICN A;  4L2X F;  4LTZ A;  5ER8 A;  1KIZ A;  2Z4V A;  3WEH A;  3NRI A;  3KRP A;  3M02 A;  3P8L A;  2EWG A;  1PS1 A;  2AEL A;  1V4I A;  4RXC A;  2F8Z F;  4MC0 A;  2E92 A;  3SDQ A;  5IMN A;  2OA6 A;  5EAU A;  3DYF A;  3MAV A;  4JXY A;  1YHM A;  1YYQ A;  4LUU A;  3N3L F;  3EGT A;  1JFG A;  4PVX F;  3SDU A;  2Q80 A;  3KRC A;  2ZCO A;  2PS6 A;  2E8V A;  3ZMC A;  4KUX A;  3V66 A;  3Q1O A;  1HM4 A;  4KK2 A;  4KPJ A;  3LVS A;  3TC1 A;  2J5C A;  4DXJ A;  4KWD A;  4KVI A;  2E90 A;  5A0J A;  3Q2Z A;  3WEG A;  3OAC B;  3ACW A;  4RXE A;  3KRA A;  4KQS A;  5ILK A;  4QXS F;  4HD1 A;  4KPD A;  3IBA A;  4JZX A;  4QPF A;  1WKZ A;  1DGP A;  3BNY A;  3VJE A;  2ZCS A;  5H9D A;  4RXD A;  2F89 F;  3WCA A;  1DI1 A;  1N22 A;  2F7M F;  4E9Z A;  4KKM A;  3ASX A;  2F94 F;  1HXC A;  2AEK A;  5B0M A;  3N1V F;  2DH4 A;  1YV5 A;  4XQS F;  3LK5 A;  1EZF A;  3WJK A;  3KRF B;  3WEI A;  3ZCD A;  3SAE A;  1VG7 A;  1RTR A;  3WCL A;  5C05 A;  1VG3 A;  1WL2 A;  4EA0 A;  5DIQ F;  5A0I A;  5B0J A;  4DZW A;  3M9U A;  2OGD A;  3TFV A;  3PYB A;  3AQC B;  3SDT A;  4KVW A;  5JV2 F;  2Z7H A;  4EA1 A;  3PH7 A;  4NFK F;  2OPN A;  5AHU B;  5IKH A;  3RMG A;  3ZMB A;  2Z4Y A;  3LOM A;  4JXN A;  3P41 A;  2E91 A;  4GAX A;  4KFA A;  4KQ5 A;  2ZCQ A;  1HXA A;  1N20 A;  3LDW A;  5JUZ F;  4XQR F;  2OPM A;  3QKC A;  3SDV A;  4H5C F;  3WC9 A;  4ZQ8 A;  2F9K F;  3Q30 A;  4LFG A;  4NG6 A;  3KRO B;  4H5E F;  2J1O A;  5DGM F;  3W7F A;  3S9V A;  3LMD A;  4WK5 A;  3V1V A;  3TS7 A;  4LZC A;  1YHK A;  3LGZ B;  1V4H A;  3WEK A;  5AEL A;  2ZCR A;  1RQI A;  3WCJ A;  1YYT A;  3OAC A;  3WCM A;  2I19 A;  4KQU A;  1UBX A;  4LLT A;  2AZL A;  3WCE A;  4LPH F;  3WJN A;  3OAB A;  4LTV A;  1V4E A;  3PYA A;  5ILJ A;  5DGN F;  3WJO A;  2PS8 A;  2RAH A;  5DJP F;  1ZW5 A;  3QQV A;  2Z4Z A;  2Z4X A;  4EA2 A;  3AQ0 A;  5KSX F;  4FJQ A;  5HN7 A;  3EZ3 A;  4E9U A;  5IK9 A;  2E93 A;  4GP1 A;  3KRF A;  3SDR A;  5DJR F;  3WSA A;  4KVY A;  3DYH A;  3P8R A;  1WL1 A;  2AZJ A;  2E8T A;  5EAS A;  3WCD A;  5B02 A;  2F8C F;  1N23 A;  3ZL6 A;  5E8K A;  5ERM A;  1YQ7 A;  5ILH A;  1N24 A;  3AQB B;  4LOB A;  5ERN A;  3DYG A;  5HN9 A;  3ID0 A;  4DHD A;  5B0I A;  1N21 A;  5IK6 A;  3VJ8 A;  2ZY1 A;  3WCF A;  4GP2 A;  4P0X A;  3N5J F;  1YYR A;  4RXA A;  4NFI F;  4LPG F;  5IL3 A;  1YYS A;  3WCC A;  3KRO A;  4NKF A;  3WCB A;  3WCG A;  5EAT A;  3WCH A;  1V4K A;  2ZEV A;  1VG2 A;  1UBV A;  4LA5 A;  1WL0 A;  3WE9 A;  3WSB A;  5IMP A;  5ILY A;  3VJB A;  3ADZ A;  4N1Z F;  2E8U A;  2Z50 A;  5IKA A;  3ACX A;  3N0G A;  2Z4W A;  3ACY A;  4RNQ A;  3OYR A;  1WL3 A;  4DI5 A;  1FPS A;  3M01 A;  4MC8 A;  5CG6 A;  3LSN A;  1RQJ A;  5ILZ A;  3APZ A;  3LG5 A;  5AFX A;  5B0L A;  3EFQ A;  3V1X A;  1N1B A;  4LFV F;  5E8L A;  5A0K A;  5B00 A;  4OMH A;  3KBK A;  2P1C A;  3WCI A;  5JV0 F;  5IN8 A;  3LZ9 A;  4KVD A;  3PKO A;  3VJD A;  2FOR A;  1YYU A;  1JFA A;  2E8W A;  3WEF A;  1UBY A;  3VJ9 A;  5B0K A;  3N1W F;  4P0V A;  3CP6 A;  5HN8 A;  5IVG A;  5IMI A;  3ZOU A;  4OGU A;  4DWB A;  4F6V A;  3CC9 A;  5ILI A;  2PS4 A;  4JYX A;  3RYW A;  4LA6 A;  2AZK A; 
#chains in the Genus database with same CATH homology
 3LEE A;  2FTZ A;  4LLS A;  4DEM F;  4GA3 A;  2ONH A;  5IM1 A;  3TFN A;  3MZV A;  3VJA A;  3NF2 A;  5CG5 A;  4LZ3 A;  1V4J A;  5DGS F;  3UCA A;  3G4D A;  4NFJ F;  2F92 F;  3LJI A;  2Q58 A;  4LIX A;  2H8O A;  4OKZ A;  4P0W A;  3S4J A;  1HXG A;  2Z78 A;  4JVJ F;  2E8X A;  2PS5 A;  3Q2Q A;  4FP4 A;  4LFE A;  3KRP B;  3LGK A;  4NKE A;  3BNX A;  2ONG A;  4F6X A;  4F62 A;  3B7L A;  3WEJ A;  4H5D F;  4XQT F;  3RYE A;  4PVY F;  2Q9Z A;  2Z7I A;  5DW7 A;  1UBW A;  3NPK A;  1WMW A;  4K10 A;  1YHL A;  2E94 A;  1WY0 A;  3AE0 A;  3OAB B;  3M0G A;  3G4F A;  5IK0 A;  5JA0 F;  5JV1 F;  3KRC B;  5DJV F;  5DHI A;  3IPI A;  4MC3 A;  1KIY A;  2ZEU A;  2PS7 A;  5ERO A;  3ICK A;  1HX9 A;  1HM7 A;  4E1E A;  2E4O A;  2QIS A;  5I1U A;  3LLW A;  5HNA A;  4LZ0 A;  3N45 F;  2Z52 A;  4LXW A;  1N1Z A;  3KRA B;  3N5H F;  2E95 A;  3N49 F;  1VG6 A;  1YJ4 A;  2J1P A;  3NPR A;  5B03 A;  3PDE A;  1VG4 A;  4RYP A;  2Q9Y A;  3RBM A;  3TFP A;  4N9U A;  4OKM A;  3ICM A;  3M00 A;  5AYP A;  2AET A;  3N3D A;  2VF6 A;  5IL8 A;  5ILD A;  3N0F A;  3VJC A;  3N46 F;  5DZ2 A;  4UMJ A;  4JZB A;  3KB9 A;  3P5R A;  4NUA A;  4Q23 A;  5DHK A;  2O1O A;  3N6K F;  5B01 A;  5E8H A;  4OMG A;  3P5P A;  4DWG A;  3CKE A;  3ICZ A;  3ICN A;  4L2X F;  4LTZ A;  5ER8 A;  1KIZ A;  2Z4V A;  3WEH A;  3NRI A;  3KRP A;  3M02 A;  3P8L A;  2EWG A;  1PS1 A;  2AEL A;  1V4I A;  4RXC A;  2F8Z F;  4MC0 A;  2E92 A;  3SDQ A;  5IMN A;  2OA6 A;  5EAU A;  3DYF A;  3MAV A;  4JXY A;  1YHM A;  1YYQ A;  4LUU A;  3N3L F;  3EGT A;  1JFG A;  4PVX F;  3SDU A;  2Q80 A;  3KRC A;  2ZCO A;  2PS6 A;  2E8V A;  3ZMC A;  4KUX A;  3V66 A;  3Q1O A;  1HM4 A;  4KK2 A;  4KPJ A;  3LVS A;  3TC1 A;  2J5C A;  4DXJ A;  4KWD A;  4KVI A;  2E90 A;  5A0J A;  3Q2Z A;  3WEG A;  3OAC B;  3ACW A;  4RXE A;  3KRA A;  4KQS A;  5ILK A;  4QXS F;  4HD1 A;  4KPD A;  3IBA A;  4JZX A;  4QPF A;  1WKZ A;  1DGP A;  3BNY A;  3VJE A;  2ZCS A;  5H9D A;  4RXD A;  2F89 F;  3WCA A;  1DI1 A;  1N22 A;  2F7M F;  4E9Z A;  4KKM A;  3ASX A;  2F94 F;  1HXC A;  2AEK A;  5B0M A;  3N1V F;  2DH4 A;  1YV5 A;  4XQS F;  3LK5 A;  1EZF A;  3WJK A;  3KRF B;  3WEI A;  3ZCD A;  3SAE A;  1VG7 A;  1RTR A;  3WCL A;  5C05 A;  1VG3 A;  1WL2 A;  4EA0 A;  5DIQ F;  5A0I A;  5B0J A;  4DZW A;  3M9U A;  2OGD A;  3TFV A;  3PYB A;  3AQC B;  3SDT A;  4KVW A;  5JV2 F;  2Z7H A;  4EA1 A;  3PH7 A;  4NFK F;  2OPN A;  5AHU B;  5IKH A;  3RMG A;  3ZMB A;  2Z4Y A;  3LOM A;  4JXN A;  3P41 A;  2E91 A;  4GAX A;  4KFA A;  4KQ5 A;  2ZCQ A;  1HXA A;  1N20 A;  3LDW A;  5JUZ F;  4XQR F;  2OPM A;  3QKC A;  3SDV A;  4H5C F;  3WC9 A;  4ZQ8 A;  2F9K F;  3Q30 A;  4LFG A;  4NG6 A;  3KRO B;  4H5E F;  2J1O A;  5DGM F;  3W7F A;  3S9V A;  3LMD A;  4WK5 A;  3V1V A;  3TS7 A;  4LZC A;  1YHK A;  3LGZ B;  1V4H A;  3WEK A;  5AEL A;  2ZCR A;  1RQI A;  3WCJ A;  1YYT A;  3OAC A;  3WCM A;  2I19 A;  4KQU A;  1UBX A;  4LLT A;  2AZL A;  3WCE A;  4LPH F;  3WJN A;  3OAB A;  4LTV A;  1V4E A;  3PYA A;  5ILJ A;  5DGN F;  3WJO A;  2PS8 A;  2RAH A;  5DJP F;  1ZW5 A;  3QQV A;  2Z4Z A;  2Z4X A;  4EA2 A;  3AQ0 A;  5KSX F;  4FJQ A;  5HN7 A;  3EZ3 A;  4E9U A;  5IK9 A;  2E93 A;  4GP1 A;  3KRF A;  3SDR A;  5DJR F;  3WSA A;  4KVY A;  3DYH A;  3P8R A;  1WL1 A;  2AZJ A;  2E8T A;  5EAS A;  3WCD A;  5B02 A;  2F8C F;  1N23 A;  3ZL6 A;  5E8K A;  5ERM A;  1YQ7 A;  5ILH A;  1N24 A;  3AQB B;  4LOB A;  5ERN A;  3DYG A;  5HN9 A;  3ID0 A;  4DHD A;  5B0I A;  1N21 A;  5IK6 A;  3VJ8 A;  2ZY1 A;  3WCF A;  4GP2 A;  4P0X A;  3N5J F;  1YYR A;  4RXA A;  4NFI F;  4LPG F;  5IL3 A;  1YYS A;  3WCC A;  3KRO A;  4NKF A;  3WCB A;  3WCG A;  5EAT A;  3WCH A;  1V4K A;  2ZEV A;  1VG2 A;  1UBV A;  4LA5 A;  1WL0 A;  3WE9 A;  3WSB A;  5IMP A;  5ILY A;  3VJB A;  3ADZ A;  4N1Z F;  2E8U A;  2Z50 A;  5IKA A;  3ACX A;  3N0G A;  2Z4W A;  3ACY A;  4RNQ A;  3OYR A;  1WL3 A;  4DI5 A;  1FPS A;  3M01 A;  4MC8 A;  5CG6 A;  3LSN A;  1RQJ A;  5ILZ A;  3APZ A;  3LG5 A;  5AFX A;  5B0L A;  3EFQ A;  3V1X A;  1N1B A;  4LFV F;  5E8L A;  5A0K A;  5B00 A;  4OMH A;  3KBK A;  2P1C A;  3WCI A;  5JV0 F;  5IN8 A;  3LZ9 A;  4KVD A;  3PKO A;  3VJD A;  2FOR A;  1YYU A;  1JFA A;  2E8W A;  3WEF A;  1UBY A;  3VJ9 A;  5B0K A;  3N1W F;  4P0V A;  3CP6 A;  5HN8 A;  5IVG A;  5IMI A;  3ZOU A;  4OGU A;  4DWB A;  4F6V A;  3CC9 A;  5ILI A;  2PS4 A;  4JYX A;  3RYW A;  4LA6 A;  2AZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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