2F8ZF

Crystal structure of human fpps in complex with zoledronate and isopentenyl diphosphate
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
346
structure length
346
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Farnesyl Diphosphate Synthase
total genus 137
structure length 346
sequence length 346
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2005-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2f8zF00
3P5PA 2EWGA 4EA1A 3WSBA 3DYFA 3LMDA 3N5HF 2E8UA 3M01A 3MZVA 4KVDA 3WEJA 1WL2A 2F92F 3CKEA 5IM1A 3TFPA 2Z4VA 5ILIA 3WCCA 1WMWA 4DI5A 1N1BA 4EA0A 1V4EA 2PS6A 1HXAA 3WEGA 2ZCSA 4XQRF 4KVIA 5JV2F 5IK6A 3ASXA 3AE0A 3P41A 4LPHF 3LVSA 3P8LA 2F8ZF 1YV5A 4KQSA 3ICKA 5DW7A 5EATA 2AZJA 3DYHA 1N21A 4KKMA 4OGUA 3B7LA 5DZ2A 3SDTA 1WL0A 2OGDA 3EZ3A 5IMIA 3VJ9A 3KRFA 3WCGA 3KROA 4RXDA 1YYRA 4E9ZA 3KRAB 4DWBA 2Z50A 3SDVA 5CG6A 5IL3A 3CC9A 4WK5A 3WCHA 4N9UA 5IMNA 2Z4XA 5JUZF 3VJCA 3N5JF 3PDEA 2E91A 1HXCA 5E8KA 4NFJF 5JV1F 5ILKA 4UMJA 3VJ8A 2E93A 3KRPB 4KPJA 1N24A 4OMGA 2RAHA 2E95A 4E9UA 3N45F 3APZA 3AQ0A 3S9VA 5DGSF 5IN8A 2J1PA 5JV0F 3LG5A 2Z52A 4LTVA 1JFGA 4PVXF 1YQ7A 4QPFA 4FJQA 3PH7A 4LLSA 4P0WA 3M00A 3WCBA 3P8RA 4JVJF 5B0JA 4N1ZF 3OACA 1RQIA 3WC9A 4KPDA 5ILYA 1UBVA 4GP2A 4F6VA 3LK5A 3KRCA 3LLWA 5I1UA 1JFAA 4LUUA 5DJRF 3RYWA 1YJ4A 3S4JA 5CG5A 2Z78A 1N23A 5B0MA 3WEHA 4DWGA 4QXSF 3WE9A 4DZWA 1DI1A 3EFQA 1VG7A 4LZ3A 2PS8A 5EROA 3N1VF 3LDWA 4DHDA 3SDQA 3TFVA 3IPIA 5IK0A 3Q2ZA 1VG4A 3M9UA 5IK9A 5DGNF 3WCMA 4JXYA 1YYTA 2AZLA 5A0IA 5B00A 5IKAA 1YHMA 4LFEA 3OABA 3RYEA 5EASA 3ACXA 3KRFB 4KVWA 1V4JA 1UBWA 3NRIA 3CP6A 5EAUA 1N1ZA 2Q9YA 5H9DA 4K10A 1RQJA 4LA5A 3SDRA 5ILHA 3LEEA 4DEMF 2PS5A 3WJOA 5ILDA 4LPGF 3V66A 2QISA 3WJNA 3PYAA 2F89F 5IL8A 3VJEA 2E90A 3LZ9A 4OMHA 4RNQA 3BNXA 3G4FA 4NKFA 5DGMF 4DXJA 4H5CF 4KVYA 4LOBA 4MC0A 3ZMBA 2Z7HA 5DHKA 1ZW5A 2E8XA 1HXGA 2I19A 3BNYA 4LFGA 4MC8A 2F94F 3SDUA 3ADZA 3PKOA 4ZQ8A 1FPSA 4OKMA 4LLTA 3OACB 4GA3A 1N20A 4NKEA 1WY0A 1WL1A 3N1WF 5A0JA 3LSNA 5HN8A 3NPKA 2ONHA 2AETA 3N46F 3ID0A 2ZCRA 1YYSA 5IMPA 3N0FA 3LGZB 3KRAA 2F9KF 1HM7A 4LIXA 3QQVA 2FTZA 3NPRA 5ERMA 5IVGA 5B02A 4KUXA 3N0GA 3WJKA 3WCEA 1PS1A 3AQBB 3ZL6A 2AZKA 3ZOUA 3KRPA 2PS7A 4KWDA 2ZCQA 3ICNA 2E8TA 4GP1A 2E4OA 2FORA 4F6XA 3LOMA 2PS4A 4NFKF 4KFAA 4EA2A 3WCDA 1VG6A 1KIZA 3VJAA 5DHIA 4MC3A 4F62A 2F7MF 5DIQF 3ACWA 3W7FA 3PYBA 1N22A 4OKZA 4JZBA 5HN9A 1VG3A 2J1OA 4JXNA 5DJPF 3KB9A 5B0KA 2J5CA 1YYUA 1V4IA 3ZMCA 3WEKA 2AELA 2OPNA 5E8HA 3KROB 5B03A 2ZCOA 3G4DA 3ICZA 1V4KA 4LTZA 3V1VA 4L2XF 3Q1OA 2Q80A 2F8CF 2Q58A 3WSAA 1YHLA 4H5EF 5C05A 2ZEVA 3Q30A 3IBAA 4RXEA 5ER8A 5HN7A 5AFXA 3KBKA 3P5RA 3RBMA 4P0XA 2ONGA 2P1CA 2AEKA 4Q23A 2E8WA 3MAVA 5ERNA 2Q9ZA 4NG6A 5HNAA 3WCIA 3OYRA 2VF6A 3M0GA 4FP4A 3LGKA 4XQTF 1YYQA 3TFNA 4LFVF 3DYGA 4PVYF 3WEIA 2Z4YA 3KRCB 3WCFA 4JYXA 2O1OA 2OA6A 2OPMA 3N6KF 1YHKA 4RYPA 1DGPA 5E8LA 5B01A 1VG2A 4KQ5A 5AHUB 4P0VA 4LZCA 4LA6A 1WKZA 3EGTA 1EZFA 5DJVF 5IKHA 3N3LF 1RTRA 4NUAA 3WCLA 4KQUA 2Z4ZA 3WEFA 5ILJA 5B0IA 5AELA 3QKCA 4XQSF 4LZ0A 3TC1A 5AYPA 3RMGA 5ILZA 3LJIA 5A0KA 4KK2A 2ZEUA 3SAEA 4H5DF 3N49F 3TS7A 1V4HA 3ICMA 3UCAA 3ACYA 3VJDA 2Z4WA 1KIYA 4LXWA 3NF2A 3WCJA 5B0LA 3AQCB 4HD1A 4RXAA 4RXCA 2H8OA 2E92A 3OABB 1UBXA 3V1XA 4NFIF 4JZXA 3WCAA 5KSXF 1HX9A 4E1EA 3VJBA 2E94A 1HM4A 4GAXA 2E8VA 3M02A 2Z7IA 1UBYA 3Q2QA 2DH4A 3ZCDA 1WL3A 2ZY1A 3N3DA 5JA0F
chains in the Genus database with same CATH superfamily
3P5PA 2EWGA 4EA1A 3WSBA 3DYFA 3LMDA 3N5HF 2E8UA 3M01A 3MZVA 4KVDA 3WEJA 1WL2A 2F92F 3CKEA 5IM1A 3TFPA 2Z4VA 5ILIA 3WCCA 1WMWA 4DI5A 1N1BA 4EA0A 1V4EA 2PS6A 1HXAA 3WEGA 2ZCSA 4XQRF 4KVIA 5JV2F 5IK6A 3ASXA 3AE0A 3P41A 4LPHF 3LVSA 3P8LA 2F8ZF 1YV5A 4KQSA 3ICKA 5DW7A 5EATA 2AZJA 3DYHA 1N21A 4KKMA 4OGUA 3B7LA 5DZ2A 3SDTA 1WL0A 2OGDA 3EZ3A 5IMIA 3VJ9A 3KRFA 3WCGA 3KROA 4RXDA 1YYRA 4E9ZA 3KRAB 4DWBA 2Z50A 3SDVA 5CG6A 5IL3A 3CC9A 4WK5A 3WCHA 4N9UA 5IMNA 2Z4XA 5JUZF 3VJCA 3N5JF 3PDEA 2E91A 1HXCA 5E8KA 4NFJF 5JV1F 5ILKA 4UMJA 3VJ8A 2E93A 3KRPB 4KPJA 1N24A 4OMGA 2RAHA 2E95A 4E9UA 3N45F 3APZA 3AQ0A 3S9VA 5DGSF 5IN8A 2J1PA 5JV0F 3LG5A 2Z52A 4LTVA 1JFGA 4PVXF 1YQ7A 4QPFA 4FJQA 3PH7A 4LLSA 4P0WA 3M00A 3WCBA 3P8RA 4JVJF 5B0JA 4N1ZF 3OACA 1RQIA 3WC9A 4KPDA 5ILYA 1UBVA 4GP2A 4F6VA 3LK5A 3KRCA 3LLWA 5I1UA 1JFAA 4LUUA 5DJRF 3RYWA 1YJ4A 3S4JA 5CG5A 2Z78A 1N23A 5B0MA 3WEHA 4DWGA 4QXSF 3WE9A 4DZWA 1DI1A 3EFQA 1VG7A 4LZ3A 2PS8A 5EROA 3N1VF 3LDWA 4DHDA 3SDQA 3TFVA 3IPIA 5IK0A 3Q2ZA 1VG4A 3M9UA 5IK9A 5DGNF 3WCMA 4JXYA 1YYTA 2AZLA 5A0IA 5B00A 5IKAA 1YHMA 4LFEA 3OABA 3RYEA 5EASA 3ACXA 3KRFB 4KVWA 1V4JA 1UBWA 3NRIA 3CP6A 5EAUA 1N1ZA 2Q9YA 5H9DA 4K10A 1RQJA 4LA5A 3SDRA 5ILHA 3LEEA 4DEMF 2PS5A 3WJOA 5ILDA 4LPGF 3V66A 2QISA 3WJNA 3PYAA 2F89F 5IL8A 3VJEA 2E90A 3LZ9A 4OMHA 4RNQA 3BNXA 3G4FA 4NKFA 5DGMF 4DXJA 4H5CF 4KVYA 4LOBA 4MC0A 3ZMBA 2Z7HA 5DHKA 1ZW5A 2E8XA 1HXGA 2I19A 3BNYA 4LFGA 4MC8A 2F94F 3SDUA 3ADZA 3PKOA 4ZQ8A 1FPSA 4OKMA 4LLTA 3OACB 4GA3A 1N20A 4NKEA 1WY0A 1WL1A 3N1WF 5A0JA 3LSNA 5HN8A 3NPKA 2ONHA 2AETA 3N46F 3ID0A 2ZCRA 1YYSA 5IMPA 3N0FA 3LGZB 3KRAA 2F9KF 1HM7A 4LIXA 3QQVA 2FTZA 3NPRA 5ERMA 5IVGA 5B02A 4KUXA 3N0GA 3WJKA 3WCEA 1PS1A 3AQBB 3ZL6A 2AZKA 3ZOUA 3KRPA 2PS7A 4KWDA 2ZCQA 3ICNA 2E8TA 4GP1A 2E4OA 2FORA 4F6XA 3LOMA 2PS4A 4NFKF 4KFAA 4EA2A 3WCDA 1VG6A 1KIZA 3VJAA 5DHIA 4MC3A 4F62A 2F7MF 5DIQF 3ACWA 3W7FA 3PYBA 1N22A 4OKZA 4JZBA 5HN9A 1VG3A 2J1OA 4JXNA 5DJPF 3KB9A 5B0KA 2J5CA 1YYUA 1V4IA 3ZMCA 3WEKA 2AELA 2OPNA 5E8HA 3KROB 5B03A 2ZCOA 3G4DA 3ICZA 1V4KA 4LTZA 3V1VA 4L2XF 3Q1OA 2Q80A 2F8CF 2Q58A 3WSAA 1YHLA 4H5EF 5C05A 2ZEVA 3Q30A 3IBAA 4RXEA 5ER8A 5HN7A 5AFXA 3KBKA 3P5RA 3RBMA 4P0XA 2ONGA 2P1CA 2AEKA 4Q23A 2E8WA 3MAVA 5ERNA 2Q9ZA 4NG6A 5HNAA 3WCIA 3OYRA 2VF6A 3M0GA 4FP4A 3LGKA 4XQTF 1YYQA 3TFNA 4LFVF 3DYGA 4PVYF 3WEIA 2Z4YA 3KRCB 3WCFA 4JYXA 2O1OA 2OA6A 2OPMA 3N6KF 1YHKA 4RYPA 1DGPA 5E8LA 5B01A 1VG2A 4KQ5A 5AHUB 4P0VA 4LZCA 4LA6A 1WKZA 3EGTA 1EZFA 5DJVF 5IKHA 3N3LF 1RTRA 4NUAA 3WCLA 4KQUA 2Z4ZA 3WEFA 5ILJA 5B0IA 5AELA 3QKCA 4XQSF 4LZ0A 3TC1A 5AYPA 3RMGA 5ILZA 3LJIA 5A0KA 4KK2A 2ZEUA 3SAEA 4H5DF 3N49F 3TS7A 1V4HA 3ICMA 3UCAA 3ACYA 3VJDA 2Z4WA 1KIYA 4LXWA 3NF2A 3WCJA 5B0LA 3AQCB 4HD1A 4RXAA 4RXCA 2H8OA 2E92A 3OABB 1UBXA 3V1XA 4NFIF 4JZXA 3WCAA 5KSXF 1HX9A 4E1EA 3VJBA 2E94A 1HM4A 4GAXA 2E8VA 3M02A 2Z7IA 1UBYA 3Q2QA 2DH4A 3ZCDA 1WL3A 2ZY1A 3N3DA 5JA0F
chains in the Genus database with same CATH topology
3P5PA 2EWGA 4EA1A 3WSBA 3DYFA 3LMDA 3N5HF 2E8UA 3M01A 3MZVA 4KVDA 3WEJA 1WL2A 2F92F 3CKEA 5IM1A 3TFPA 2Z4VA 5ILIA 3WCCA 1WMWA 4DI5A 1N1BA 4EA0A 1V4EA 2PS6A 1HXAA 3WEGA 2ZCSA 4XQRF 4KVIA 5JV2F 5IK6A 3ASXA 3AE0A 3P41A 4LPHF 3LVSA 3P8LA 2F8ZF 1YV5A 4KQSA 3ICKA 5DW7A 5EATA 2AZJA 3DYHA 1N21A 4KKMA 4OGUA 3B7LA 5DZ2A 3SDTA 1WL0A 2OGDA 3EZ3A 5IMIA 3VJ9A 3KRFA 3WCGA 3KROA 4RXDA 1YYRA 4E9ZA 3KRAB 4DWBA 2Z50A 3SDVA 5CG6A 5IL3A 3CC9A 4WK5A 3WCHA 4N9UA 5IMNA 2Z4XA 5JUZF 3VJCA 3N5JF 3PDEA 2E91A 1HXCA 5E8KA 4NFJF 5JV1F 5ILKA 4UMJA 3VJ8A 2E93A 3KRPB 4KPJA 1N24A 4OMGA 2RAHA 2E95A 4E9UA 3N45F 3APZA 3AQ0A 3S9VA 5DGSF 5IN8A 2J1PA 5JV0F 3LG5A 2Z52A 4LTVA 1JFGA 4PVXF 1YQ7A 4QPFA 4FJQA 3PH7A 4LLSA 4P0WA 3M00A 3WCBA 3P8RA 4JVJF 5B0JA 4N1ZF 3OACA 1RQIA 3WC9A 4KPDA 5ILYA 1UBVA 4GP2A 4F6VA 3LK5A 3KRCA 3LLWA 5I1UA 1JFAA 4LUUA 5DJRF 3RYWA 1YJ4A 3S4JA 5CG5A 2Z78A 1N23A 5B0MA 3WEHA 4DWGA 4QXSF 3WE9A 4DZWA 1DI1A 3EFQA 1VG7A 4LZ3A 2PS8A 5EROA 3N1VF 3LDWA 4DHDA 3SDQA 3TFVA 3IPIA 5IK0A 3Q2ZA 1VG4A 3M9UA 5IK9A 5DGNF 3WCMA 4JXYA 1YYTA 2AZLA 5A0IA 5B00A 5IKAA 1YHMA 4LFEA 3OABA 3RYEA 5EASA 3ACXA 3KRFB 4KVWA 1V4JA 1UBWA 3NRIA 3CP6A 5EAUA 1N1ZA 2Q9YA 5H9DA 4K10A 1RQJA 4LA5A 3SDRA 5ILHA 3LEEA 4DEMF 2PS5A 3WJOA 5ILDA 4LPGF 3V66A 2QISA 3WJNA 3PYAA 2F89F 5IL8A 3VJEA 2E90A 3LZ9A 4OMHA 4RNQA 3BNXA 3G4FA 4NKFA 5DGMF 4DXJA 4H5CF 4KVYA 4LOBA 4MC0A 3ZMBA 2Z7HA 5DHKA 1ZW5A 2E8XA 1HXGA 2I19A 3BNYA 4LFGA 4MC8A 2F94F 3SDUA 3ADZA 3PKOA 4ZQ8A 1FPSA 4OKMA 4LLTA 3OACB 4GA3A 1N20A 4NKEA 1WY0A 1WL1A 3N1WF 5A0JA 3LSNA 5HN8A 3NPKA 2ONHA 2AETA 3N46F 3ID0A 2ZCRA 1YYSA 5IMPA 3N0FA 3LGZB 3KRAA 2F9KF 1HM7A 4LIXA 3QQVA 2FTZA 3NPRA 5ERMA 5IVGA 5B02A 4KUXA 3N0GA 3WJKA 3WCEA 1PS1A 3AQBB 3ZL6A 2AZKA 3ZOUA 3KRPA 2PS7A 4KWDA 2ZCQA 3ICNA 2E8TA 4GP1A 2E4OA 2FORA 4F6XA 3LOMA 2PS4A 4NFKF 4KFAA 4EA2A 3WCDA 1VG6A 1KIZA 3VJAA 5DHIA 4MC3A 4F62A 2F7MF 5DIQF 3ACWA 3W7FA 3PYBA 1N22A 4OKZA 4JZBA 5HN9A 1VG3A 2J1OA 4JXNA 5DJPF 3KB9A 5B0KA 2J5CA 1YYUA 1V4IA 3ZMCA 3WEKA 2AELA 2OPNA 5E8HA 3KROB 5B03A 2ZCOA 3G4DA 3ICZA 1V4KA 4LTZA 3V1VA 4L2XF 3Q1OA 2Q80A 2F8CF 2Q58A 3WSAA 1YHLA 4H5EF 5C05A 2ZEVA 3Q30A 3IBAA 4RXEA 5ER8A 5HN7A 5AFXA 3KBKA 3P5RA 3RBMA 4P0XA 2ONGA 2P1CA 2AEKA 4Q23A 2E8WA 3MAVA 5ERNA 2Q9ZA 4NG6A 5HNAA 3WCIA 3OYRA 2VF6A 3M0GA 4FP4A 3LGKA 4XQTF 1YYQA 3TFNA 4LFVF 3DYGA 4PVYF 3WEIA 2Z4YA 3KRCB 3WCFA 4JYXA 2O1OA 2OA6A 2OPMA 3N6KF 1YHKA 4RYPA 1DGPA 5E8LA 5B01A 1VG2A 4KQ5A 5AHUB 4P0VA 4LZCA 4LA6A 1WKZA 3EGTA 1EZFA 5DJVF 5IKHA 3N3LF 1RTRA 4NUAA 3WCLA 4KQUA 2Z4ZA 3WEFA 5ILJA 5B0IA 5AELA 3QKCA 4XQSF 4LZ0A 3TC1A 5AYPA 3RMGA 5ILZA 3LJIA 5A0KA 4KK2A 2ZEUA 3SAEA 4H5DF 3N49F 3TS7A 1V4HA 3ICMA 3UCAA 3ACYA 3VJDA 2Z4WA 1KIYA 4LXWA 3NF2A 3WCJA 5B0LA 3AQCB 4HD1A 4RXAA 4RXCA 2H8OA 2E92A 3OABB 1UBXA 3V1XA 4NFIF 4JZXA 3WCAA 5KSXF 1HX9A 4E1EA 3VJBA 2E94A 1HM4A 4GAXA 2E8VA 3M02A 2Z7IA 1UBYA 3Q2QA 2DH4A 3ZCDA 1WL3A 2ZY1A 3N3DA 5JA0F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P5P A;  2EWG A;  4EA1 A;  3WSB A;  3DYF A;  3LMD A;  3N5H F;  2E8U A;  3M01 A;  3MZV A;  4KVD A;  3WEJ A;  1WL2 A;  2F92 F;  3CKE A;  5IM1 A;  3TFP A;  2Z4V A;  5ILI A;  3WCC A;  1WMW A;  4DI5 A;  1N1B A;  4EA0 A;  1V4E A;  2PS6 A;  1HXA A;  3WEG A;  2ZCS A;  4XQR F;  4KVI A;  5JV2 F;  5IK6 A;  3ASX A;  3AE0 A;  3P41 A;  4LPH F;  3LVS A;  3P8L A;  2F8Z F;  1YV5 A;  4KQS A;  3ICK A;  5DW7 A;  5EAT A;  2AZJ A;  3DYH A;  1N21 A;  4KKM A;  4OGU A;  3B7L A;  5DZ2 A;  3SDT A;  1WL0 A;  2OGD A;  3EZ3 A;  5IMI A;  3VJ9 A;  3KRF A;  3WCG A;  3KRO A;  4RXD A;  1YYR A;  4E9Z A;  3KRA B;  4DWB A;  2Z50 A;  3SDV A;  5CG6 A;  5IL3 A;  3CC9 A;  4WK5 A;  3WCH A;  4N9U A;  5IMN A;  2Z4X A;  5JUZ F;  3VJC A;  3N5J F;  3PDE A;  2E91 A;  1HXC A;  5E8K A;  4NFJ F;  5JV1 F;  5ILK A;  4UMJ A;  3VJ8 A;  2E93 A;  3KRP B;  4KPJ A;  1N24 A;  4OMG A;  2RAH A;  2E95 A;  4E9U A;  3N45 F;  3APZ A;  3AQ0 A;  3S9V A;  5DGS F;  5IN8 A;  2J1P A;  5JV0 F;  3LG5 A;  2Z52 A;  4LTV A;  1JFG A;  4PVX F;  1YQ7 A;  4QPF A;  4FJQ A;  3PH7 A;  4LLS A;  4P0W A;  3M00 A;  3WCB A;  3P8R A;  4JVJ F;  5B0J A;  4N1Z F;  3OAC A;  1RQI A;  3WC9 A;  4KPD A;  5ILY A;  1UBV A;  4GP2 A;  4F6V A;  3LK5 A;  3KRC A;  3LLW A;  5I1U A;  1JFA A;  4LUU A;  5DJR F;  3RYW A;  1YJ4 A;  3S4J A;  5CG5 A;  2Z78 A;  1N23 A;  5B0M A;  3WEH A;  4DWG A;  4QXS F;  3WE9 A;  4DZW A;  1DI1 A;  3EFQ A;  1VG7 A;  4LZ3 A;  2PS8 A;  5ERO A;  3N1V F;  3LDW A;  4DHD A;  3SDQ A;  3TFV A;  3IPI A;  5IK0 A;  3Q2Z A;  1VG4 A;  3M9U A;  5IK9 A;  5DGN F;  3WCM A;  4JXY A;  1YYT A;  2AZL A;  5A0I A;  5B00 A;  5IKA A;  1YHM A;  4LFE A;  3OAB A;  3RYE A;  5EAS A;  3ACX A;  3KRF B;  4KVW A;  1V4J A;  1UBW A;  3NRI A;  3CP6 A;  5EAU A;  1N1Z A;  2Q9Y A;  5H9D A;  4K10 A;  1RQJ A;  4LA5 A;  3SDR A;  5ILH A;  3LEE A;  4DEM F;  2PS5 A;  3WJO A;  5ILD A;  4LPG F;  3V66 A;  2QIS A;  3WJN A;  3PYA A;  2F89 F;  5IL8 A;  3VJE A;  2E90 A;  3LZ9 A;  4OMH A;  4RNQ A;  3BNX A;  3G4F A;  4NKF A;  5DGM F;  4DXJ A;  4H5C F;  4KVY A;  4LOB A;  4MC0 A;  3ZMB A;  2Z7H A;  5DHK A;  1ZW5 A;  2E8X A;  1HXG A;  2I19 A;  3BNY A;  4LFG A;  4MC8 A;  2F94 F;  3SDU A;  3ADZ A;  3PKO A;  4ZQ8 A;  1FPS A;  4OKM A;  4LLT A;  3OAC B;  4GA3 A;  1N20 A;  4NKE A;  1WY0 A;  1WL1 A;  3N1W F;  5A0J A;  3LSN A;  5HN8 A;  3NPK A;  2ONH A;  2AET A;  3N46 F;  3ID0 A;  2ZCR A;  1YYS A;  5IMP A;  3N0F A;  3LGZ B;  3KRA A;  2F9K F;  1HM7 A;  4LIX A;  3QQV A;  2FTZ A;  3NPR A;  5ERM A;  5IVG A;  5B02 A;  4KUX A;  3N0G A;  3WJK A;  3WCE A;  1PS1 A;  3AQB B;  3ZL6 A;  2AZK A;  3ZOU A;  3KRP A;  2PS7 A;  4KWD A;  2ZCQ A;  3ICN A;  2E8T A;  4GP1 A;  2E4O A;  2FOR A;  4F6X A;  3LOM A;  2PS4 A;  4NFK F;  4KFA A;  4EA2 A;  3WCD A;  1VG6 A;  1KIZ A;  3VJA A;  5DHI A;  4MC3 A;  4F62 A;  2F7M F;  5DIQ F;  3ACW A;  3W7F A;  3PYB A;  1N22 A;  4OKZ A;  4JZB A;  5HN9 A;  1VG3 A;  2J1O A;  4JXN A;  5DJP F;  3KB9 A;  5B0K A;  2J5C A;  1YYU A;  1V4I A;  3ZMC A;  3WEK A;  2AEL A;  2OPN A;  5E8H A;  3KRO B;  5B03 A;  2ZCO A;  3G4D A;  3ICZ A;  1V4K A;  4LTZ A;  3V1V A;  4L2X F;  3Q1O A;  2Q80 A;  2F8C F;  2Q58 A;  3WSA A;  1YHL A;  4H5E F;  5C05 A;  2ZEV A;  3Q30 A;  3IBA A;  4RXE A;  5ER8 A;  5HN7 A;  5AFX A;  3KBK A;  3P5R A;  3RBM A;  4P0X A;  2ONG A;  2P1C A;  2AEK A;  4Q23 A;  2E8W A;  3MAV A;  5ERN A;  2Q9Z A;  4NG6 A;  5HNA A;  3WCI A;  3OYR A;  2VF6 A;  3M0G A;  4FP4 A;  3LGK A;  4XQT F;  1YYQ A;  3TFN A;  4LFV F;  3DYG A;  4PVY F;  3WEI A;  2Z4Y A;  3KRC B;  3WCF A;  4JYX A;  2O1O A;  2OA6 A;  2OPM A;  3N6K F;  1YHK A;  4RYP A;  1DGP A;  5E8L A;  5B01 A;  1VG2 A;  4KQ5 A;  5AHU B;  4P0V A;  4LZC A;  4LA6 A;  1WKZ A;  3EGT A;  1EZF A;  5DJV F;  5IKH A;  3N3L F;  1RTR A;  4NUA A;  3WCL A;  4KQU A;  2Z4Z A;  3WEF A;  5ILJ A;  5B0I A;  5AEL A;  3QKC A;  4XQS F;  4LZ0 A;  3TC1 A;  5AYP A;  3RMG A;  5ILZ A;  3LJI A;  5A0K A;  4KK2 A;  2ZEU A;  3SAE A;  4H5D F;  3N49 F;  3TS7 A;  1V4H A;  3ICM A;  3UCA A;  3ACY A;  3VJD A;  2Z4W A;  1KIY A;  4LXW A;  3NF2 A;  3WCJ A;  5B0L A;  3AQC B;  4HD1 A;  4RXA A;  4RXC A;  2H8O A;  2E92 A;  3OAB B;  1UBX A;  3V1X A;  4NFI F;  4JZX A;  3WCA A;  5KSX F;  1HX9 A;  4E1E A;  3VJB A;  2E94 A;  1HM4 A;  4GAX A;  2E8V A;  3M02 A;  2Z7I A;  1UBY A;  3Q2Q A;  2DH4 A;  3ZCD A;  1WL3 A;  2ZY1 A;  3N3D A;  5JA0 F; 
#chains in the Genus database with same CATH topology
 3P5P A;  2EWG A;  4EA1 A;  3WSB A;  3DYF A;  3LMD A;  3N5H F;  2E8U A;  3M01 A;  3MZV A;  4KVD A;  3WEJ A;  1WL2 A;  2F92 F;  3CKE A;  5IM1 A;  3TFP A;  2Z4V A;  5ILI A;  3WCC A;  1WMW A;  4DI5 A;  1N1B A;  4EA0 A;  1V4E A;  2PS6 A;  1HXA A;  3WEG A;  2ZCS A;  4XQR F;  4KVI A;  5JV2 F;  5IK6 A;  3ASX A;  3AE0 A;  3P41 A;  4LPH F;  3LVS A;  3P8L A;  2F8Z F;  1YV5 A;  4KQS A;  3ICK A;  5DW7 A;  5EAT A;  2AZJ A;  3DYH A;  1N21 A;  4KKM A;  4OGU A;  3B7L A;  5DZ2 A;  3SDT A;  1WL0 A;  2OGD A;  3EZ3 A;  5IMI A;  3VJ9 A;  3KRF A;  3WCG A;  3KRO A;  4RXD A;  1YYR A;  4E9Z A;  3KRA B;  4DWB A;  2Z50 A;  3SDV A;  5CG6 A;  5IL3 A;  3CC9 A;  4WK5 A;  3WCH A;  4N9U A;  5IMN A;  2Z4X A;  5JUZ F;  3VJC A;  3N5J F;  3PDE A;  2E91 A;  1HXC A;  5E8K A;  4NFJ F;  5JV1 F;  5ILK A;  4UMJ A;  3VJ8 A;  2E93 A;  3KRP B;  4KPJ A;  1N24 A;  4OMG A;  2RAH A;  2E95 A;  4E9U A;  3N45 F;  3APZ A;  3AQ0 A;  3S9V A;  5DGS F;  5IN8 A;  2J1P A;  5JV0 F;  3LG5 A;  2Z52 A;  4LTV A;  1JFG A;  4PVX F;  1YQ7 A;  4QPF A;  4FJQ A;  3PH7 A;  4LLS A;  4P0W A;  3M00 A;  3WCB A;  3P8R A;  4JVJ F;  5B0J A;  4N1Z F;  3OAC A;  1RQI A;  3WC9 A;  4KPD A;  5ILY A;  1UBV A;  4GP2 A;  4F6V A;  3LK5 A;  3KRC A;  3LLW A;  5I1U A;  1JFA A;  4LUU A;  5DJR F;  3RYW A;  1YJ4 A;  3S4J A;  5CG5 A;  2Z78 A;  1N23 A;  5B0M A;  3WEH A;  4DWG A;  4QXS F;  3WE9 A;  4DZW A;  1DI1 A;  3EFQ A;  1VG7 A;  4LZ3 A;  2PS8 A;  5ERO A;  3N1V F;  3LDW A;  4DHD A;  3SDQ A;  3TFV A;  3IPI A;  5IK0 A;  3Q2Z A;  1VG4 A;  3M9U A;  5IK9 A;  5DGN F;  3WCM A;  4JXY A;  1YYT A;  2AZL A;  5A0I A;  5B00 A;  5IKA A;  1YHM A;  4LFE A;  3OAB A;  3RYE A;  5EAS A;  3ACX A;  3KRF B;  4KVW A;  1V4J A;  1UBW A;  3NRI A;  3CP6 A;  5EAU A;  1N1Z A;  2Q9Y A;  5H9D A;  4K10 A;  1RQJ A;  4LA5 A;  3SDR A;  5ILH A;  3LEE A;  4DEM F;  2PS5 A;  3WJO A;  5ILD A;  4LPG F;  3V66 A;  2QIS A;  3WJN A;  3PYA A;  2F89 F;  5IL8 A;  3VJE A;  2E90 A;  3LZ9 A;  4OMH A;  4RNQ A;  3BNX A;  3G4F A;  4NKF A;  5DGM F;  4DXJ A;  4H5C F;  4KVY A;  4LOB A;  4MC0 A;  3ZMB A;  2Z7H A;  5DHK A;  1ZW5 A;  2E8X A;  1HXG A;  2I19 A;  3BNY A;  4LFG A;  4MC8 A;  2F94 F;  3SDU A;  3ADZ A;  3PKO A;  4ZQ8 A;  1FPS A;  4OKM A;  4LLT A;  3OAC B;  4GA3 A;  1N20 A;  4NKE A;  1WY0 A;  1WL1 A;  3N1W F;  5A0J A;  3LSN A;  5HN8 A;  3NPK A;  2ONH A;  2AET A;  3N46 F;  3ID0 A;  2ZCR A;  1YYS A;  5IMP A;  3N0F A;  3LGZ B;  3KRA A;  2F9K F;  1HM7 A;  4LIX A;  3QQV A;  2FTZ A;  3NPR A;  5ERM A;  5IVG A;  5B02 A;  4KUX A;  3N0G A;  3WJK A;  3WCE A;  1PS1 A;  3AQB B;  3ZL6 A;  2AZK A;  3ZOU A;  3KRP A;  2PS7 A;  4KWD A;  2ZCQ A;  3ICN A;  2E8T A;  4GP1 A;  2E4O A;  2FOR A;  4F6X A;  3LOM A;  2PS4 A;  4NFK F;  4KFA A;  4EA2 A;  3WCD A;  1VG6 A;  1KIZ A;  3VJA A;  5DHI A;  4MC3 A;  4F62 A;  2F7M F;  5DIQ F;  3ACW A;  3W7F A;  3PYB A;  1N22 A;  4OKZ A;  4JZB A;  5HN9 A;  1VG3 A;  2J1O A;  4JXN A;  5DJP F;  3KB9 A;  5B0K A;  2J5C A;  1YYU A;  1V4I A;  3ZMC A;  3WEK A;  2AEL A;  2OPN A;  5E8H A;  3KRO B;  5B03 A;  2ZCO A;  3G4D A;  3ICZ A;  1V4K A;  4LTZ A;  3V1V A;  4L2X F;  3Q1O A;  2Q80 A;  2F8C F;  2Q58 A;  3WSA A;  1YHL A;  4H5E F;  5C05 A;  2ZEV A;  3Q30 A;  3IBA A;  4RXE A;  5ER8 A;  5HN7 A;  5AFX A;  3KBK A;  3P5R A;  3RBM A;  4P0X A;  2ONG A;  2P1C A;  2AEK A;  4Q23 A;  2E8W A;  3MAV A;  5ERN A;  2Q9Z A;  4NG6 A;  5HNA A;  3WCI A;  3OYR A;  2VF6 A;  3M0G A;  4FP4 A;  3LGK A;  4XQT F;  1YYQ A;  3TFN A;  4LFV F;  3DYG A;  4PVY F;  3WEI A;  2Z4Y A;  3KRC B;  3WCF A;  4JYX A;  2O1O A;  2OA6 A;  2OPM A;  3N6K F;  1YHK A;  4RYP A;  1DGP A;  5E8L A;  5B01 A;  1VG2 A;  4KQ5 A;  5AHU B;  4P0V A;  4LZC A;  4LA6 A;  1WKZ A;  3EGT A;  1EZF A;  5DJV F;  5IKH A;  3N3L F;  1RTR A;  4NUA A;  3WCL A;  4KQU A;  2Z4Z A;  3WEF A;  5ILJ A;  5B0I A;  5AEL A;  3QKC A;  4XQS F;  4LZ0 A;  3TC1 A;  5AYP A;  3RMG A;  5ILZ A;  3LJI A;  5A0K A;  4KK2 A;  2ZEU A;  3SAE A;  4H5D F;  3N49 F;  3TS7 A;  1V4H A;  3ICM A;  3UCA A;  3ACY A;  3VJD A;  2Z4W A;  1KIY A;  4LXW A;  3NF2 A;  3WCJ A;  5B0L A;  3AQC B;  4HD1 A;  4RXA A;  4RXC A;  2H8O A;  2E92 A;  3OAB B;  1UBX A;  3V1X A;  4NFI F;  4JZX A;  3WCA A;  5KSX F;  1HX9 A;  4E1E A;  3VJB A;  2E94 A;  1HM4 A;  4GAX A;  2E8V A;  3M02 A;  2Z7I A;  1UBY A;  3Q2Q A;  2DH4 A;  3ZCD A;  1WL3 A;  2ZY1 A;  3N3D A;  5JA0 F; 
#chains in the Genus database with same CATH homology
 3P5P A;  2EWG A;  4EA1 A;  3WSB A;  3DYF A;  3LMD A;  3N5H F;  2E8U A;  3M01 A;  3MZV A;  4KVD A;  3WEJ A;  1WL2 A;  2F92 F;  3CKE A;  5IM1 A;  3TFP A;  2Z4V A;  5ILI A;  3WCC A;  1WMW A;  4DI5 A;  1N1B A;  4EA0 A;  1V4E A;  2PS6 A;  1HXA A;  3WEG A;  2ZCS A;  4XQR F;  4KVI A;  5JV2 F;  5IK6 A;  3ASX A;  3AE0 A;  3P41 A;  4LPH F;  3LVS A;  3P8L A;  2F8Z F;  1YV5 A;  4KQS A;  3ICK A;  5DW7 A;  5EAT A;  2AZJ A;  3DYH A;  1N21 A;  4KKM A;  4OGU A;  3B7L A;  5DZ2 A;  3SDT A;  1WL0 A;  2OGD A;  3EZ3 A;  5IMI A;  3VJ9 A;  3KRF A;  3WCG A;  3KRO A;  4RXD A;  1YYR A;  4E9Z A;  3KRA B;  4DWB A;  2Z50 A;  3SDV A;  5CG6 A;  5IL3 A;  3CC9 A;  4WK5 A;  3WCH A;  4N9U A;  5IMN A;  2Z4X A;  5JUZ F;  3VJC A;  3N5J F;  3PDE A;  2E91 A;  1HXC A;  5E8K A;  4NFJ F;  5JV1 F;  5ILK A;  4UMJ A;  3VJ8 A;  2E93 A;  3KRP B;  4KPJ A;  1N24 A;  4OMG A;  2RAH A;  2E95 A;  4E9U A;  3N45 F;  3APZ A;  3AQ0 A;  3S9V A;  5DGS F;  5IN8 A;  2J1P A;  5JV0 F;  3LG5 A;  2Z52 A;  4LTV A;  1JFG A;  4PVX F;  1YQ7 A;  4QPF A;  4FJQ A;  3PH7 A;  4LLS A;  4P0W A;  3M00 A;  3WCB A;  3P8R A;  4JVJ F;  5B0J A;  4N1Z F;  3OAC A;  1RQI A;  3WC9 A;  4KPD A;  5ILY A;  1UBV A;  4GP2 A;  4F6V A;  3LK5 A;  3KRC A;  3LLW A;  5I1U A;  1JFA A;  4LUU A;  5DJR F;  3RYW A;  1YJ4 A;  3S4J A;  5CG5 A;  2Z78 A;  1N23 A;  5B0M A;  3WEH A;  4DWG A;  4QXS F;  3WE9 A;  4DZW A;  1DI1 A;  3EFQ A;  1VG7 A;  4LZ3 A;  2PS8 A;  5ERO A;  3N1V F;  3LDW A;  4DHD A;  3SDQ A;  3TFV A;  3IPI A;  5IK0 A;  3Q2Z A;  1VG4 A;  3M9U A;  5IK9 A;  5DGN F;  3WCM A;  4JXY A;  1YYT A;  2AZL A;  5A0I A;  5B00 A;  5IKA A;  1YHM A;  4LFE A;  3OAB A;  3RYE A;  5EAS A;  3ACX A;  3KRF B;  4KVW A;  1V4J A;  1UBW A;  3NRI A;  3CP6 A;  5EAU A;  1N1Z A;  2Q9Y A;  5H9D A;  4K10 A;  1RQJ A;  4LA5 A;  3SDR A;  5ILH A;  3LEE A;  4DEM F;  2PS5 A;  3WJO A;  5ILD A;  4LPG F;  3V66 A;  2QIS A;  3WJN A;  3PYA A;  2F89 F;  5IL8 A;  3VJE A;  2E90 A;  3LZ9 A;  4OMH A;  4RNQ A;  3BNX A;  3G4F A;  4NKF A;  5DGM F;  4DXJ A;  4H5C F;  4KVY A;  4LOB A;  4MC0 A;  3ZMB A;  2Z7H A;  5DHK A;  1ZW5 A;  2E8X A;  1HXG A;  2I19 A;  3BNY A;  4LFG A;  4MC8 A;  2F94 F;  3SDU A;  3ADZ A;  3PKO A;  4ZQ8 A;  1FPS A;  4OKM A;  4LLT A;  3OAC B;  4GA3 A;  1N20 A;  4NKE A;  1WY0 A;  1WL1 A;  3N1W F;  5A0J A;  3LSN A;  5HN8 A;  3NPK A;  2ONH A;  2AET A;  3N46 F;  3ID0 A;  2ZCR A;  1YYS A;  5IMP A;  3N0F A;  3LGZ B;  3KRA A;  2F9K F;  1HM7 A;  4LIX A;  3QQV A;  2FTZ A;  3NPR A;  5ERM A;  5IVG A;  5B02 A;  4KUX A;  3N0G A;  3WJK A;  3WCE A;  1PS1 A;  3AQB B;  3ZL6 A;  2AZK A;  3ZOU A;  3KRP A;  2PS7 A;  4KWD A;  2ZCQ A;  3ICN A;  2E8T A;  4GP1 A;  2E4O A;  2FOR A;  4F6X A;  3LOM A;  2PS4 A;  4NFK F;  4KFA A;  4EA2 A;  3WCD A;  1VG6 A;  1KIZ A;  3VJA A;  5DHI A;  4MC3 A;  4F62 A;  2F7M F;  5DIQ F;  3ACW A;  3W7F A;  3PYB A;  1N22 A;  4OKZ A;  4JZB A;  5HN9 A;  1VG3 A;  2J1O A;  4JXN A;  5DJP F;  3KB9 A;  5B0K A;  2J5C A;  1YYU A;  1V4I A;  3ZMC A;  3WEK A;  2AEL A;  2OPN A;  5E8H A;  3KRO B;  5B03 A;  2ZCO A;  3G4D A;  3ICZ A;  1V4K A;  4LTZ A;  3V1V A;  4L2X F;  3Q1O A;  2Q80 A;  2F8C F;  2Q58 A;  3WSA A;  1YHL A;  4H5E F;  5C05 A;  2ZEV A;  3Q30 A;  3IBA A;  4RXE A;  5ER8 A;  5HN7 A;  5AFX A;  3KBK A;  3P5R A;  3RBM A;  4P0X A;  2ONG A;  2P1C A;  2AEK A;  4Q23 A;  2E8W A;  3MAV A;  5ERN A;  2Q9Z A;  4NG6 A;  5HNA A;  3WCI A;  3OYR A;  2VF6 A;  3M0G A;  4FP4 A;  3LGK A;  4XQT F;  1YYQ A;  3TFN A;  4LFV F;  3DYG A;  4PVY F;  3WEI A;  2Z4Y A;  3KRC B;  3WCF A;  4JYX A;  2O1O A;  2OA6 A;  2OPM A;  3N6K F;  1YHK A;  4RYP A;  1DGP A;  5E8L A;  5B01 A;  1VG2 A;  4KQ5 A;  5AHU B;  4P0V A;  4LZC A;  4LA6 A;  1WKZ A;  3EGT A;  1EZF A;  5DJV F;  5IKH A;  3N3L F;  1RTR A;  4NUA A;  3WCL A;  4KQU A;  2Z4Z A;  3WEF A;  5ILJ A;  5B0I A;  5AEL A;  3QKC A;  4XQS F;  4LZ0 A;  3TC1 A;  5AYP A;  3RMG A;  5ILZ A;  3LJI A;  5A0K A;  4KK2 A;  2ZEU A;  3SAE A;  4H5D F;  3N49 F;  3TS7 A;  1V4H A;  3ICM A;  3UCA A;  3ACY A;  3VJD A;  2Z4W A;  1KIY A;  4LXW A;  3NF2 A;  3WCJ A;  5B0L A;  3AQC B;  4HD1 A;  4RXA A;  4RXC A;  2H8O A;  2E92 A;  3OAB B;  1UBX A;  3V1X A;  4NFI F;  4JZX A;  3WCA A;  5KSX F;  1HX9 A;  4E1E A;  3VJB A;  2E94 A;  1HM4 A;  4GAX A;  2E8V A;  3M02 A;  2Z7I A;  1UBY A;  3Q2Q A;  2DH4 A;  3ZCD A;  1WL3 A;  2ZY1 A;  3N3D A;  5JA0 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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