2Q80A

Crystal structure of human geranylgeranyl pyrophosphate synthase bound to ggpp
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
291
structure length
285
Chain Sequence
ETVQRILLEPYKYLLQLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNASLLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGLEKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPTEEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTLGLFFQIRDDYANLHSKSFCEDLTEGKFSFPTIHAIWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYTRNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of human geranylgeranyl pyrophosphate synthase reveals a novel hexameric arrangement and inhibitory product binding
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Geranylgeranyl pyrophosphate synthetase
total genus 124
structure length 285
sequence length 291
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-06-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2q80A00
3WC9A 2PS6A 3P5PA 1YYRA 3N3LF 4GP2A 3M02A 4P0VA 4Q23A 5B0MA 3WCAA 1V4HA 3OACA 3ACYA 4JXNA 4E9ZA 3Q2ZA 1YV5A 3WCDA 4LPHF 4JZXA 3RMGA 4KPDA 2F8CF 4F6XA 3EZ3A 5B0IA 5C05A 4NKFA 4LOBA 4NKEA 5IMPA 2F9KF 1HXCA 4JVJF 3WEIA 1UBXA 5ERNA 4LPGF 2E95A 3N6KF 4P0XA 2Z4YA 3ZCDA 4KVYA 2AZLA 4KQUA 3OABA 5EATA 2FORA 3ICZA 2AZKA 4LFGA 2PS8A 5IL8A 3ASXA 3AE0A 4RXAA 3WCJA 1RQJA 3WEHA 5HN8A 3W7FA 5A0KA 3N3DA 3RBMA 5IM1A 4UMJA 4LA5A 5HN7A 3KRCB 1PS1A 4LLSA 5B0KA 5ERMA 3WSBA 3TFVA 2AZJA 3VJEA 2ZY1A 1DI1A 3EFQA 2Q9YA 2Q80A 3LG5A 4RXDA 2Z4VA 2ZEVA 1N20A 1WKZA 4OKMA 1JFGA 4KK2A 2PS4A 1VG7A 2F94F 4LZCA 3VJ9A 4KVIA 4LTVA 4LXWA 2Z4ZA 3AQBB 1YYUA 1RQIA 4LIXA 3TC1A 3ICNA 2AEKA 1VG2A 3ID0A 4XQSF 3M0GA 5HNAA 2DH4A 5B00A 3NRIA 5IVGA 3APZA 1EZFA 3N45F 3KRAB 4RYPA 2FTZA 4DWBA 5AYPA 2ZCOA 5ER8A 5EAUA 3TFPA 3Q1OA 5AHUB 1WL3A 3WJOA 3WCCA 2ZCRA 1V4IA 4KUXA 3N46F 2F8ZF 3VJDA 3LZ9A 3QQVA 3M9UA 2Z4WA 5E8KA 1UBVA 4RXCA 3EGTA 4NFIF 4OMHA 3M01A 3CKEA 3V66A 3WCIA 3WJKA 3WCHA 1YHLA 1KIZA 5IMIA 5DJVF 3KRFB 2ONGA 3N0FA 1YQ7A 2Q9ZA 1VG6A 1YYTA 3V1XA 2Z78A 1YJ4A 4DZWA 3MAVA 3WSAA 2OPNA 2Q58A 5JA0F 2Z7IA 5ILKA 5B0LA 1YHMA 4LZ0A 3TS7A 1WMWA 3BNYA 3KBKA 4E1EA 3CC9A 2Z4XA 5DIQF 4MC3A 4WK5A 2PS7A 4LFVF 5A0JA 3NPKA 3LGZB 3Q2QA 5A0IA 2EWGA 5ILHA 5IN8A 4KVDA 5DGNF 2VF6A 4GA3A 4N9UA 5DJRF 3TFNA 3N5JF 4EA0A 1YYSA 5B01A 3WCEA 1UBWA 1VG3A 2PS5A 3VJAA 1N1ZA 3ZMCA 3B7LA 1WY0A 2OGDA 4QPFA 2ZEUA 4P0WA 1ZW5A 3N1VF 5EROA 1YYQA 4DHDA 4NFJF 4RNQA 4E9UA 5IL3A 4XQRF 5KSXF 3P5RA 1HX9A 3VJCA 3ZOUA 3Q30A 3QKCA 4FP4A 3KRPB 5CG5A 5JUZF 5AELA 3WCBA 3SAEA 5IMNA 3N0GA 3KB9A 3G4DA 3PH7A 2E8WA 1UBYA 5JV0F 3VJBA 2E4OA 3LOMA 3WEJA 5EASA 1V4JA 3IPIA 5B0JA 4H5DF 5ILIA 2E90A 3MZVA 3BNXA 1FPSA 4GAXA 2ONHA 4DWGA 2E92A 4RXEA 3ZMBA 3DYGA 1V4EA 1HXAA 1VG4A 1YHKA 3LEEA 4LZ3A 5DJPF 2E8UA 1DGPA 3PKOA 4MC8A 4JYXA 3OYRA 4KVWA 3LJIA 1N1BA 3N49F 3LSNA 3S9VA 3V1VA 2ZCSA 1KIYA 3DYFA 1JFAA 4H5EF 5IK6A 3NPRA 3N1WF 5DW7A 5JV2F 4LTZA 4LFEA 3WEFA 2Z7HA 5DHIA 3KROB 4OGUA 3AQCB 3LMDA 4KQ5A 3P41A 4KKMA 5ILZA 5AFXA 3SDQA 3SDVA 1RTRA 3IBAA 2Z52A 4NFKF 4NUAA 4EA1A 4JXYA 5ILDA 4QXSF 1WL0A 4FJQA 3KRCA 2E8VA 1HM7A 3N5HF 1WL1A 2E8TA 2Z50A 4DXJA 3WCFA 3LVSA 3S4JA 1N22A 3LGKA 3WEKA 1HXGA 3VJ8A 5E8HA 1N21A 3KRPA 3SDTA 2E91A 4OKZA 2QISA 2E8XA 3LK5A 4KFAA 5H9DA 2AELA 3SDRA 4EA2A 3ICKA 3ACWA 4ZQ8A 1WL2A 4LLTA 4F6VA 4KPJA 3RYEA 3UCAA 2OA6A 3OACB 5HN9A 1V4KA 4F62A 2J1PA 5IKAA 4HD1A 3NF2A 5IKHA 3WJNA 3P8RA 3KRAA 2E94A 5DHKA 2P1CA 5B02A 2F7MF 4PVXF 4JZBA 3WCMA 3LDWA 2H8OA 4OMGA 3ACXA 5DGSF 4K10A 2F89F 3CP6A 5I1UA 3AQ0A 5ILJA 3DYHA 2J5CA 4XQTF 5CG6A 1HM4A 3PYBA 5DZ2A 2RAHA 4L2XF 4GP1A 3M00A 3ICMA 3OABB 5E8LA 4KQSA 4NG6A 3KROA 2OPMA 3KRFA 2F92F 3LLWA 4N1ZF 4PVYF 5JV1F 3WE9A 2O1OA 5DGMF 3RYWA 4DI5A 1N23A 3SDUA 4LA6A 3WCGA 3WCLA 5B03A 2I19A 3PDEA 2J1OA 3ADZA 4KWDA 3WEGA 3ZL6A 2AETA 3PYAA 5ILYA 2ZCQA 3G4FA 5IK9A 4DEMF 4LUUA 3P8LA 4H5CF 1N24A 4MC0A 2E93A 5IK0A
chains in the Genus database with same CATH superfamily
3WC9A 2PS6A 3P5PA 1YYRA 3N3LF 4GP2A 3M02A 4P0VA 4Q23A 5B0MA 3WCAA 1V4HA 3OACA 3ACYA 4JXNA 4E9ZA 3Q2ZA 1YV5A 3WCDA 4LPHF 4JZXA 3RMGA 4KPDA 2F8CF 4F6XA 3EZ3A 5B0IA 5C05A 4NKFA 4LOBA 4NKEA 5IMPA 2F9KF 1HXCA 4JVJF 3WEIA 1UBXA 5ERNA 4LPGF 2E95A 3N6KF 4P0XA 2Z4YA 3ZCDA 4KVYA 2AZLA 4KQUA 3OABA 5EATA 2FORA 3ICZA 2AZKA 4LFGA 2PS8A 5IL8A 3ASXA 3AE0A 4RXAA 3WCJA 1RQJA 3WEHA 5HN8A 3W7FA 5A0KA 3N3DA 3RBMA 5IM1A 4UMJA 4LA5A 5HN7A 3KRCB 1PS1A 4LLSA 5B0KA 5ERMA 3WSBA 3TFVA 2AZJA 3VJEA 2ZY1A 1DI1A 3EFQA 2Q9YA 2Q80A 3LG5A 4RXDA 2Z4VA 2ZEVA 1N20A 1WKZA 4OKMA 1JFGA 4KK2A 2PS4A 1VG7A 2F94F 4LZCA 3VJ9A 4KVIA 4LTVA 4LXWA 2Z4ZA 3AQBB 1YYUA 1RQIA 4LIXA 3TC1A 3ICNA 2AEKA 1VG2A 3ID0A 4XQSF 3M0GA 5HNAA 2DH4A 5B00A 3NRIA 5IVGA 3APZA 1EZFA 3N45F 3KRAB 4RYPA 2FTZA 4DWBA 5AYPA 2ZCOA 5ER8A 5EAUA 3TFPA 3Q1OA 5AHUB 1WL3A 3WJOA 3WCCA 2ZCRA 1V4IA 4KUXA 3N46F 2F8ZF 3VJDA 3LZ9A 3QQVA 3M9UA 2Z4WA 5E8KA 1UBVA 4RXCA 3EGTA 4NFIF 4OMHA 3M01A 3CKEA 3V66A 3WCIA 3WJKA 3WCHA 1YHLA 1KIZA 5IMIA 5DJVF 3KRFB 2ONGA 3N0FA 1YQ7A 2Q9ZA 1VG6A 1YYTA 3V1XA 2Z78A 1YJ4A 4DZWA 3MAVA 3WSAA 2OPNA 2Q58A 5JA0F 2Z7IA 5ILKA 5B0LA 1YHMA 4LZ0A 3TS7A 1WMWA 3BNYA 3KBKA 4E1EA 3CC9A 2Z4XA 5DIQF 4MC3A 4WK5A 2PS7A 4LFVF 5A0JA 3NPKA 3LGZB 3Q2QA 5A0IA 2EWGA 5ILHA 5IN8A 4KVDA 5DGNF 2VF6A 4GA3A 4N9UA 5DJRF 3TFNA 3N5JF 4EA0A 1YYSA 5B01A 3WCEA 1UBWA 1VG3A 2PS5A 3VJAA 1N1ZA 3ZMCA 3B7LA 1WY0A 2OGDA 4QPFA 2ZEUA 4P0WA 1ZW5A 3N1VF 5EROA 1YYQA 4DHDA 4NFJF 4RNQA 4E9UA 5IL3A 4XQRF 5KSXF 3P5RA 1HX9A 3VJCA 3ZOUA 3Q30A 3QKCA 4FP4A 3KRPB 5CG5A 5JUZF 5AELA 3WCBA 3SAEA 5IMNA 3N0GA 3KB9A 3G4DA 3PH7A 2E8WA 1UBYA 5JV0F 3VJBA 2E4OA 3LOMA 3WEJA 5EASA 1V4JA 3IPIA 5B0JA 4H5DF 5ILIA 2E90A 3MZVA 3BNXA 1FPSA 4GAXA 2ONHA 4DWGA 2E92A 4RXEA 3ZMBA 3DYGA 1V4EA 1HXAA 1VG4A 1YHKA 3LEEA 4LZ3A 5DJPF 2E8UA 1DGPA 3PKOA 4MC8A 4JYXA 3OYRA 4KVWA 3LJIA 1N1BA 3N49F 3LSNA 3S9VA 3V1VA 2ZCSA 1KIYA 3DYFA 1JFAA 4H5EF 5IK6A 3NPRA 3N1WF 5DW7A 5JV2F 4LTZA 4LFEA 3WEFA 2Z7HA 5DHIA 3KROB 4OGUA 3AQCB 3LMDA 4KQ5A 3P41A 4KKMA 5ILZA 5AFXA 3SDQA 3SDVA 1RTRA 3IBAA 2Z52A 4NFKF 4NUAA 4EA1A 4JXYA 5ILDA 4QXSF 1WL0A 4FJQA 3KRCA 2E8VA 1HM7A 3N5HF 1WL1A 2E8TA 2Z50A 4DXJA 3WCFA 3LVSA 3S4JA 1N22A 3LGKA 3WEKA 1HXGA 3VJ8A 5E8HA 1N21A 3KRPA 3SDTA 2E91A 4OKZA 2QISA 2E8XA 3LK5A 4KFAA 5H9DA 2AELA 3SDRA 4EA2A 3ICKA 3ACWA 4ZQ8A 1WL2A 4LLTA 4F6VA 4KPJA 3RYEA 3UCAA 2OA6A 3OACB 5HN9A 1V4KA 4F62A 2J1PA 5IKAA 4HD1A 3NF2A 5IKHA 3WJNA 3P8RA 3KRAA 2E94A 5DHKA 2P1CA 5B02A 2F7MF 4PVXF 4JZBA 3WCMA 3LDWA 2H8OA 4OMGA 3ACXA 5DGSF 4K10A 2F89F 3CP6A 5I1UA 3AQ0A 5ILJA 3DYHA 2J5CA 4XQTF 5CG6A 1HM4A 3PYBA 5DZ2A 2RAHA 4L2XF 4GP1A 3M00A 3ICMA 3OABB 5E8LA 4KQSA 4NG6A 3KROA 2OPMA 3KRFA 2F92F 3LLWA 4N1ZF 4PVYF 5JV1F 3WE9A 2O1OA 5DGMF 3RYWA 4DI5A 1N23A 3SDUA 4LA6A 3WCGA 3WCLA 5B03A 2I19A 3PDEA 2J1OA 3ADZA 4KWDA 3WEGA 3ZL6A 2AETA 3PYAA 5ILYA 2ZCQA 3G4FA 5IK9A 4DEMF 4LUUA 3P8LA 4H5CF 1N24A 4MC0A 2E93A 5IK0A
chains in the Genus database with same CATH topology
3WC9A 2PS6A 3P5PA 1YYRA 3N3LF 4GP2A 3M02A 4P0VA 4Q23A 5B0MA 3WCAA 1V4HA 3OACA 3ACYA 4JXNA 4E9ZA 3Q2ZA 1YV5A 3WCDA 4LPHF 4JZXA 3RMGA 4KPDA 2F8CF 4F6XA 3EZ3A 5B0IA 5C05A 4NKFA 4LOBA 4NKEA 5IMPA 2F9KF 1HXCA 4JVJF 3WEIA 1UBXA 5ERNA 4LPGF 2E95A 3N6KF 4P0XA 2Z4YA 3ZCDA 4KVYA 2AZLA 4KQUA 3OABA 5EATA 2FORA 3ICZA 2AZKA 4LFGA 2PS8A 5IL8A 3ASXA 3AE0A 4RXAA 3WCJA 1RQJA 3WEHA 5HN8A 3W7FA 5A0KA 3N3DA 3RBMA 5IM1A 4UMJA 4LA5A 5HN7A 3KRCB 1PS1A 4LLSA 5B0KA 5ERMA 3WSBA 3TFVA 2AZJA 3VJEA 2ZY1A 1DI1A 3EFQA 2Q9YA 2Q80A 3LG5A 4RXDA 2Z4VA 2ZEVA 1N20A 1WKZA 4OKMA 1JFGA 4KK2A 2PS4A 1VG7A 2F94F 4LZCA 3VJ9A 4KVIA 4LTVA 4LXWA 2Z4ZA 3AQBB 1YYUA 1RQIA 4LIXA 3TC1A 3ICNA 2AEKA 1VG2A 3ID0A 4XQSF 3M0GA 5HNAA 2DH4A 5B00A 3NRIA 5IVGA 3APZA 1EZFA 3N45F 3KRAB 4RYPA 2FTZA 4DWBA 5AYPA 2ZCOA 5ER8A 5EAUA 3TFPA 3Q1OA 5AHUB 1WL3A 3WJOA 3WCCA 2ZCRA 1V4IA 4KUXA 3N46F 2F8ZF 3VJDA 3LZ9A 3QQVA 3M9UA 2Z4WA 5E8KA 1UBVA 4RXCA 3EGTA 4NFIF 4OMHA 3M01A 3CKEA 3V66A 3WCIA 3WJKA 3WCHA 1YHLA 1KIZA 5IMIA 5DJVF 3KRFB 2ONGA 3N0FA 1YQ7A 2Q9ZA 1VG6A 1YYTA 3V1XA 2Z78A 1YJ4A 4DZWA 3MAVA 3WSAA 2OPNA 2Q58A 5JA0F 2Z7IA 5ILKA 5B0LA 1YHMA 4LZ0A 3TS7A 1WMWA 3BNYA 3KBKA 4E1EA 3CC9A 2Z4XA 5DIQF 4MC3A 4WK5A 2PS7A 4LFVF 5A0JA 3NPKA 3LGZB 3Q2QA 5A0IA 2EWGA 5ILHA 5IN8A 4KVDA 5DGNF 2VF6A 4GA3A 4N9UA 5DJRF 3TFNA 3N5JF 4EA0A 1YYSA 5B01A 3WCEA 1UBWA 1VG3A 2PS5A 3VJAA 1N1ZA 3ZMCA 3B7LA 1WY0A 2OGDA 4QPFA 2ZEUA 4P0WA 1ZW5A 3N1VF 5EROA 1YYQA 4DHDA 4NFJF 4RNQA 4E9UA 5IL3A 4XQRF 5KSXF 3P5RA 1HX9A 3VJCA 3ZOUA 3Q30A 3QKCA 4FP4A 3KRPB 5CG5A 5JUZF 5AELA 3WCBA 3SAEA 5IMNA 3N0GA 3KB9A 3G4DA 3PH7A 2E8WA 1UBYA 5JV0F 3VJBA 2E4OA 3LOMA 3WEJA 5EASA 1V4JA 3IPIA 5B0JA 4H5DF 5ILIA 2E90A 3MZVA 3BNXA 1FPSA 4GAXA 2ONHA 4DWGA 2E92A 4RXEA 3ZMBA 3DYGA 1V4EA 1HXAA 1VG4A 1YHKA 3LEEA 4LZ3A 5DJPF 2E8UA 1DGPA 3PKOA 4MC8A 4JYXA 3OYRA 4KVWA 3LJIA 1N1BA 3N49F 3LSNA 3S9VA 3V1VA 2ZCSA 1KIYA 3DYFA 1JFAA 4H5EF 5IK6A 3NPRA 3N1WF 5DW7A 5JV2F 4LTZA 4LFEA 3WEFA 2Z7HA 5DHIA 3KROB 4OGUA 3AQCB 3LMDA 4KQ5A 3P41A 4KKMA 5ILZA 5AFXA 3SDQA 3SDVA 1RTRA 3IBAA 2Z52A 4NFKF 4NUAA 4EA1A 4JXYA 5ILDA 4QXSF 1WL0A 4FJQA 3KRCA 2E8VA 1HM7A 3N5HF 1WL1A 2E8TA 2Z50A 4DXJA 3WCFA 3LVSA 3S4JA 1N22A 3LGKA 3WEKA 1HXGA 3VJ8A 5E8HA 1N21A 3KRPA 3SDTA 2E91A 4OKZA 2QISA 2E8XA 3LK5A 4KFAA 5H9DA 2AELA 3SDRA 4EA2A 3ICKA 3ACWA 4ZQ8A 1WL2A 4LLTA 4F6VA 4KPJA 3RYEA 3UCAA 2OA6A 3OACB 5HN9A 1V4KA 4F62A 2J1PA 5IKAA 4HD1A 3NF2A 5IKHA 3WJNA 3P8RA 3KRAA 2E94A 5DHKA 2P1CA 5B02A 2F7MF 4PVXF 4JZBA 3WCMA 3LDWA 2H8OA 4OMGA 3ACXA 5DGSF 4K10A 2F89F 3CP6A 5I1UA 3AQ0A 5ILJA 3DYHA 2J5CA 4XQTF 5CG6A 1HM4A 3PYBA 5DZ2A 2RAHA 4L2XF 4GP1A 3M00A 3ICMA 3OABB 5E8LA 4KQSA 4NG6A 3KROA 2OPMA 3KRFA 2F92F 3LLWA 4N1ZF 4PVYF 5JV1F 3WE9A 2O1OA 5DGMF 3RYWA 4DI5A 1N23A 3SDUA 4LA6A 3WCGA 3WCLA 5B03A 2I19A 3PDEA 2J1OA 3ADZA 4KWDA 3WEGA 3ZL6A 2AETA 3PYAA 5ILYA 2ZCQA 3G4FA 5IK9A 4DEMF 4LUUA 3P8LA 4H5CF 1N24A 4MC0A 2E93A 5IK0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WC9 A;  2PS6 A;  3P5P A;  1YYR A;  3N3L F;  4GP2 A;  3M02 A;  4P0V A;  4Q23 A;  5B0M A;  3WCA A;  1V4H A;  3OAC A;  3ACY A;  4JXN A;  4E9Z A;  3Q2Z A;  1YV5 A;  3WCD A;  4LPH F;  4JZX A;  3RMG A;  4KPD A;  2F8C F;  4F6X A;  3EZ3 A;  5B0I A;  5C05 A;  4NKF A;  4LOB A;  4NKE A;  5IMP A;  2F9K F;  1HXC A;  4JVJ F;  3WEI A;  1UBX A;  5ERN A;  4LPG F;  2E95 A;  3N6K F;  4P0X A;  2Z4Y A;  3ZCD A;  4KVY A;  2AZL A;  4KQU A;  3OAB A;  5EAT A;  2FOR A;  3ICZ A;  2AZK A;  4LFG A;  2PS8 A;  5IL8 A;  3ASX A;  3AE0 A;  4RXA A;  3WCJ A;  1RQJ A;  3WEH A;  5HN8 A;  3W7F A;  5A0K A;  3N3D A;  3RBM A;  5IM1 A;  4UMJ A;  4LA5 A;  5HN7 A;  3KRC B;  1PS1 A;  4LLS A;  5B0K A;  5ERM A;  3WSB A;  3TFV A;  2AZJ A;  3VJE A;  2ZY1 A;  1DI1 A;  3EFQ A;  2Q9Y A;  2Q80 A;  3LG5 A;  4RXD A;  2Z4V A;  2ZEV A;  1N20 A;  1WKZ A;  4OKM A;  1JFG A;  4KK2 A;  2PS4 A;  1VG7 A;  2F94 F;  4LZC A;  3VJ9 A;  4KVI A;  4LTV A;  4LXW A;  2Z4Z A;  3AQB B;  1YYU A;  1RQI A;  4LIX A;  3TC1 A;  3ICN A;  2AEK A;  1VG2 A;  3ID0 A;  4XQS F;  3M0G A;  5HNA A;  2DH4 A;  5B00 A;  3NRI A;  5IVG A;  3APZ A;  1EZF A;  3N45 F;  3KRA B;  4RYP A;  2FTZ A;  4DWB A;  5AYP A;  2ZCO A;  5ER8 A;  5EAU A;  3TFP A;  3Q1O A;  5AHU B;  1WL3 A;  3WJO A;  3WCC A;  2ZCR A;  1V4I A;  4KUX A;  3N46 F;  2F8Z F;  3VJD A;  3LZ9 A;  3QQV A;  3M9U A;  2Z4W A;  5E8K A;  1UBV A;  4RXC A;  3EGT A;  4NFI F;  4OMH A;  3M01 A;  3CKE A;  3V66 A;  3WCI A;  3WJK A;  3WCH A;  1YHL A;  1KIZ A;  5IMI A;  5DJV F;  3KRF B;  2ONG A;  3N0F A;  1YQ7 A;  2Q9Z A;  1VG6 A;  1YYT A;  3V1X A;  2Z78 A;  1YJ4 A;  4DZW A;  3MAV A;  3WSA A;  2OPN A;  2Q58 A;  5JA0 F;  2Z7I A;  5ILK A;  5B0L A;  1YHM A;  4LZ0 A;  3TS7 A;  1WMW A;  3BNY A;  3KBK A;  4E1E A;  3CC9 A;  2Z4X A;  5DIQ F;  4MC3 A;  4WK5 A;  2PS7 A;  4LFV F;  5A0J A;  3NPK A;  3LGZ B;  3Q2Q A;  5A0I A;  2EWG A;  5ILH A;  5IN8 A;  4KVD A;  5DGN F;  2VF6 A;  4GA3 A;  4N9U A;  5DJR F;  3TFN A;  3N5J F;  4EA0 A;  1YYS A;  5B01 A;  3WCE A;  1UBW A;  1VG3 A;  2PS5 A;  3VJA A;  1N1Z A;  3ZMC A;  3B7L A;  1WY0 A;  2OGD A;  4QPF A;  2ZEU A;  4P0W A;  1ZW5 A;  3N1V F;  5ERO A;  1YYQ A;  4DHD A;  4NFJ F;  4RNQ A;  4E9U A;  5IL3 A;  4XQR F;  5KSX F;  3P5R A;  1HX9 A;  3VJC A;  3ZOU A;  3Q30 A;  3QKC A;  4FP4 A;  3KRP B;  5CG5 A;  5JUZ F;  5AEL A;  3WCB A;  3SAE A;  5IMN A;  3N0G A;  3KB9 A;  3G4D A;  3PH7 A;  2E8W A;  1UBY A;  5JV0 F;  3VJB A;  2E4O A;  3LOM A;  3WEJ A;  5EAS A;  1V4J A;  3IPI A;  5B0J A;  4H5D F;  5ILI A;  2E90 A;  3MZV A;  3BNX A;  1FPS A;  4GAX A;  2ONH A;  4DWG A;  2E92 A;  4RXE A;  3ZMB A;  3DYG A;  1V4E A;  1HXA A;  1VG4 A;  1YHK A;  3LEE A;  4LZ3 A;  5DJP F;  2E8U A;  1DGP A;  3PKO A;  4MC8 A;  4JYX A;  3OYR A;  4KVW A;  3LJI A;  1N1B A;  3N49 F;  3LSN A;  3S9V A;  3V1V A;  2ZCS A;  1KIY A;  3DYF A;  1JFA A;  4H5E F;  5IK6 A;  3NPR A;  3N1W F;  5DW7 A;  5JV2 F;  4LTZ A;  4LFE A;  3WEF A;  2Z7H A;  5DHI A;  3KRO B;  4OGU A;  3AQC B;  3LMD A;  4KQ5 A;  3P41 A;  4KKM A;  5ILZ A;  5AFX A;  3SDQ A;  3SDV A;  1RTR A;  3IBA A;  2Z52 A;  4NFK F;  4NUA A;  4EA1 A;  4JXY A;  5ILD A;  4QXS F;  1WL0 A;  4FJQ A;  3KRC A;  2E8V A;  1HM7 A;  3N5H F;  1WL1 A;  2E8T A;  2Z50 A;  4DXJ A;  3WCF A;  3LVS A;  3S4J A;  1N22 A;  3LGK A;  3WEK A;  1HXG A;  3VJ8 A;  5E8H A;  1N21 A;  3KRP A;  3SDT A;  2E91 A;  4OKZ A;  2QIS A;  2E8X A;  3LK5 A;  4KFA A;  5H9D A;  2AEL A;  3SDR A;  4EA2 A;  3ICK A;  3ACW A;  4ZQ8 A;  1WL2 A;  4LLT A;  4F6V A;  4KPJ A;  3RYE A;  3UCA A;  2OA6 A;  3OAC B;  5HN9 A;  1V4K A;  4F62 A;  2J1P A;  5IKA A;  4HD1 A;  3NF2 A;  5IKH A;  3WJN A;  3P8R A;  3KRA A;  2E94 A;  5DHK A;  2P1C A;  5B02 A;  2F7M F;  4PVX F;  4JZB A;  3WCM A;  3LDW A;  2H8O A;  4OMG A;  3ACX A;  5DGS F;  4K10 A;  2F89 F;  3CP6 A;  5I1U A;  3AQ0 A;  5ILJ A;  3DYH A;  2J5C A;  4XQT F;  5CG6 A;  1HM4 A;  3PYB A;  5DZ2 A;  2RAH A;  4L2X F;  4GP1 A;  3M00 A;  3ICM A;  3OAB B;  5E8L A;  4KQS A;  4NG6 A;  3KRO A;  2OPM A;  3KRF A;  2F92 F;  3LLW A;  4N1Z F;  4PVY F;  5JV1 F;  3WE9 A;  2O1O A;  5DGM F;  3RYW A;  4DI5 A;  1N23 A;  3SDU A;  4LA6 A;  3WCG A;  3WCL A;  5B03 A;  2I19 A;  3PDE A;  2J1O A;  3ADZ A;  4KWD A;  3WEG A;  3ZL6 A;  2AET A;  3PYA A;  5ILY A;  2ZCQ A;  3G4F A;  5IK9 A;  4DEM F;  4LUU A;  3P8L A;  4H5C F;  1N24 A;  4MC0 A;  2E93 A;  5IK0 A; 
#chains in the Genus database with same CATH topology
 3WC9 A;  2PS6 A;  3P5P A;  1YYR A;  3N3L F;  4GP2 A;  3M02 A;  4P0V A;  4Q23 A;  5B0M A;  3WCA A;  1V4H A;  3OAC A;  3ACY A;  4JXN A;  4E9Z A;  3Q2Z A;  1YV5 A;  3WCD A;  4LPH F;  4JZX A;  3RMG A;  4KPD A;  2F8C F;  4F6X A;  3EZ3 A;  5B0I A;  5C05 A;  4NKF A;  4LOB A;  4NKE A;  5IMP A;  2F9K F;  1HXC A;  4JVJ F;  3WEI A;  1UBX A;  5ERN A;  4LPG F;  2E95 A;  3N6K F;  4P0X A;  2Z4Y A;  3ZCD A;  4KVY A;  2AZL A;  4KQU A;  3OAB A;  5EAT A;  2FOR A;  3ICZ A;  2AZK A;  4LFG A;  2PS8 A;  5IL8 A;  3ASX A;  3AE0 A;  4RXA A;  3WCJ A;  1RQJ A;  3WEH A;  5HN8 A;  3W7F A;  5A0K A;  3N3D A;  3RBM A;  5IM1 A;  4UMJ A;  4LA5 A;  5HN7 A;  3KRC B;  1PS1 A;  4LLS A;  5B0K A;  5ERM A;  3WSB A;  3TFV A;  2AZJ A;  3VJE A;  2ZY1 A;  1DI1 A;  3EFQ A;  2Q9Y A;  2Q80 A;  3LG5 A;  4RXD A;  2Z4V A;  2ZEV A;  1N20 A;  1WKZ A;  4OKM A;  1JFG A;  4KK2 A;  2PS4 A;  1VG7 A;  2F94 F;  4LZC A;  3VJ9 A;  4KVI A;  4LTV A;  4LXW A;  2Z4Z A;  3AQB B;  1YYU A;  1RQI A;  4LIX A;  3TC1 A;  3ICN A;  2AEK A;  1VG2 A;  3ID0 A;  4XQS F;  3M0G A;  5HNA A;  2DH4 A;  5B00 A;  3NRI A;  5IVG A;  3APZ A;  1EZF A;  3N45 F;  3KRA B;  4RYP A;  2FTZ A;  4DWB A;  5AYP A;  2ZCO A;  5ER8 A;  5EAU A;  3TFP A;  3Q1O A;  5AHU B;  1WL3 A;  3WJO A;  3WCC A;  2ZCR A;  1V4I A;  4KUX A;  3N46 F;  2F8Z F;  3VJD A;  3LZ9 A;  3QQV A;  3M9U A;  2Z4W A;  5E8K A;  1UBV A;  4RXC A;  3EGT A;  4NFI F;  4OMH A;  3M01 A;  3CKE A;  3V66 A;  3WCI A;  3WJK A;  3WCH A;  1YHL A;  1KIZ A;  5IMI A;  5DJV F;  3KRF B;  2ONG A;  3N0F A;  1YQ7 A;  2Q9Z A;  1VG6 A;  1YYT A;  3V1X A;  2Z78 A;  1YJ4 A;  4DZW A;  3MAV A;  3WSA A;  2OPN A;  2Q58 A;  5JA0 F;  2Z7I A;  5ILK A;  5B0L A;  1YHM A;  4LZ0 A;  3TS7 A;  1WMW A;  3BNY A;  3KBK A;  4E1E A;  3CC9 A;  2Z4X A;  5DIQ F;  4MC3 A;  4WK5 A;  2PS7 A;  4LFV F;  5A0J A;  3NPK A;  3LGZ B;  3Q2Q A;  5A0I A;  2EWG A;  5ILH A;  5IN8 A;  4KVD A;  5DGN F;  2VF6 A;  4GA3 A;  4N9U A;  5DJR F;  3TFN A;  3N5J F;  4EA0 A;  1YYS A;  5B01 A;  3WCE A;  1UBW A;  1VG3 A;  2PS5 A;  3VJA A;  1N1Z A;  3ZMC A;  3B7L A;  1WY0 A;  2OGD A;  4QPF A;  2ZEU A;  4P0W A;  1ZW5 A;  3N1V F;  5ERO A;  1YYQ A;  4DHD A;  4NFJ F;  4RNQ A;  4E9U A;  5IL3 A;  4XQR F;  5KSX F;  3P5R A;  1HX9 A;  3VJC A;  3ZOU A;  3Q30 A;  3QKC A;  4FP4 A;  3KRP B;  5CG5 A;  5JUZ F;  5AEL A;  3WCB A;  3SAE A;  5IMN A;  3N0G A;  3KB9 A;  3G4D A;  3PH7 A;  2E8W A;  1UBY A;  5JV0 F;  3VJB A;  2E4O A;  3LOM A;  3WEJ A;  5EAS A;  1V4J A;  3IPI A;  5B0J A;  4H5D F;  5ILI A;  2E90 A;  3MZV A;  3BNX A;  1FPS A;  4GAX A;  2ONH A;  4DWG A;  2E92 A;  4RXE A;  3ZMB A;  3DYG A;  1V4E A;  1HXA A;  1VG4 A;  1YHK A;  3LEE A;  4LZ3 A;  5DJP F;  2E8U A;  1DGP A;  3PKO A;  4MC8 A;  4JYX A;  3OYR A;  4KVW A;  3LJI A;  1N1B A;  3N49 F;  3LSN A;  3S9V A;  3V1V A;  2ZCS A;  1KIY A;  3DYF A;  1JFA A;  4H5E F;  5IK6 A;  3NPR A;  3N1W F;  5DW7 A;  5JV2 F;  4LTZ A;  4LFE A;  3WEF A;  2Z7H A;  5DHI A;  3KRO B;  4OGU A;  3AQC B;  3LMD A;  4KQ5 A;  3P41 A;  4KKM A;  5ILZ A;  5AFX A;  3SDQ A;  3SDV A;  1RTR A;  3IBA A;  2Z52 A;  4NFK F;  4NUA A;  4EA1 A;  4JXY A;  5ILD A;  4QXS F;  1WL0 A;  4FJQ A;  3KRC A;  2E8V A;  1HM7 A;  3N5H F;  1WL1 A;  2E8T A;  2Z50 A;  4DXJ A;  3WCF A;  3LVS A;  3S4J A;  1N22 A;  3LGK A;  3WEK A;  1HXG A;  3VJ8 A;  5E8H A;  1N21 A;  3KRP A;  3SDT A;  2E91 A;  4OKZ A;  2QIS A;  2E8X A;  3LK5 A;  4KFA A;  5H9D A;  2AEL A;  3SDR A;  4EA2 A;  3ICK A;  3ACW A;  4ZQ8 A;  1WL2 A;  4LLT A;  4F6V A;  4KPJ A;  3RYE A;  3UCA A;  2OA6 A;  3OAC B;  5HN9 A;  1V4K A;  4F62 A;  2J1P A;  5IKA A;  4HD1 A;  3NF2 A;  5IKH A;  3WJN A;  3P8R A;  3KRA A;  2E94 A;  5DHK A;  2P1C A;  5B02 A;  2F7M F;  4PVX F;  4JZB A;  3WCM A;  3LDW A;  2H8O A;  4OMG A;  3ACX A;  5DGS F;  4K10 A;  2F89 F;  3CP6 A;  5I1U A;  3AQ0 A;  5ILJ A;  3DYH A;  2J5C A;  4XQT F;  5CG6 A;  1HM4 A;  3PYB A;  5DZ2 A;  2RAH A;  4L2X F;  4GP1 A;  3M00 A;  3ICM A;  3OAB B;  5E8L A;  4KQS A;  4NG6 A;  3KRO A;  2OPM A;  3KRF A;  2F92 F;  3LLW A;  4N1Z F;  4PVY F;  5JV1 F;  3WE9 A;  2O1O A;  5DGM F;  3RYW A;  4DI5 A;  1N23 A;  3SDU A;  4LA6 A;  3WCG A;  3WCL A;  5B03 A;  2I19 A;  3PDE A;  2J1O A;  3ADZ A;  4KWD A;  3WEG A;  3ZL6 A;  2AET A;  3PYA A;  5ILY A;  2ZCQ A;  3G4F A;  5IK9 A;  4DEM F;  4LUU A;  3P8L A;  4H5C F;  1N24 A;  4MC0 A;  2E93 A;  5IK0 A; 
#chains in the Genus database with same CATH homology
 3WC9 A;  2PS6 A;  3P5P A;  1YYR A;  3N3L F;  4GP2 A;  3M02 A;  4P0V A;  4Q23 A;  5B0M A;  3WCA A;  1V4H A;  3OAC A;  3ACY A;  4JXN A;  4E9Z A;  3Q2Z A;  1YV5 A;  3WCD A;  4LPH F;  4JZX A;  3RMG A;  4KPD A;  2F8C F;  4F6X A;  3EZ3 A;  5B0I A;  5C05 A;  4NKF A;  4LOB A;  4NKE A;  5IMP A;  2F9K F;  1HXC A;  4JVJ F;  3WEI A;  1UBX A;  5ERN A;  4LPG F;  2E95 A;  3N6K F;  4P0X A;  2Z4Y A;  3ZCD A;  4KVY A;  2AZL A;  4KQU A;  3OAB A;  5EAT A;  2FOR A;  3ICZ A;  2AZK A;  4LFG A;  2PS8 A;  5IL8 A;  3ASX A;  3AE0 A;  4RXA A;  3WCJ A;  1RQJ A;  3WEH A;  5HN8 A;  3W7F A;  5A0K A;  3N3D A;  3RBM A;  5IM1 A;  4UMJ A;  4LA5 A;  5HN7 A;  3KRC B;  1PS1 A;  4LLS A;  5B0K A;  5ERM A;  3WSB A;  3TFV A;  2AZJ A;  3VJE A;  2ZY1 A;  1DI1 A;  3EFQ A;  2Q9Y A;  2Q80 A;  3LG5 A;  4RXD A;  2Z4V A;  2ZEV A;  1N20 A;  1WKZ A;  4OKM A;  1JFG A;  4KK2 A;  2PS4 A;  1VG7 A;  2F94 F;  4LZC A;  3VJ9 A;  4KVI A;  4LTV A;  4LXW A;  2Z4Z A;  3AQB B;  1YYU A;  1RQI A;  4LIX A;  3TC1 A;  3ICN A;  2AEK A;  1VG2 A;  3ID0 A;  4XQS F;  3M0G A;  5HNA A;  2DH4 A;  5B00 A;  3NRI A;  5IVG A;  3APZ A;  1EZF A;  3N45 F;  3KRA B;  4RYP A;  2FTZ A;  4DWB A;  5AYP A;  2ZCO A;  5ER8 A;  5EAU A;  3TFP A;  3Q1O A;  5AHU B;  1WL3 A;  3WJO A;  3WCC A;  2ZCR A;  1V4I A;  4KUX A;  3N46 F;  2F8Z F;  3VJD A;  3LZ9 A;  3QQV A;  3M9U A;  2Z4W A;  5E8K A;  1UBV A;  4RXC A;  3EGT A;  4NFI F;  4OMH A;  3M01 A;  3CKE A;  3V66 A;  3WCI A;  3WJK A;  3WCH A;  1YHL A;  1KIZ A;  5IMI A;  5DJV F;  3KRF B;  2ONG A;  3N0F A;  1YQ7 A;  2Q9Z A;  1VG6 A;  1YYT A;  3V1X A;  2Z78 A;  1YJ4 A;  4DZW A;  3MAV A;  3WSA A;  2OPN A;  2Q58 A;  5JA0 F;  2Z7I A;  5ILK A;  5B0L A;  1YHM A;  4LZ0 A;  3TS7 A;  1WMW A;  3BNY A;  3KBK A;  4E1E A;  3CC9 A;  2Z4X A;  5DIQ F;  4MC3 A;  4WK5 A;  2PS7 A;  4LFV F;  5A0J A;  3NPK A;  3LGZ B;  3Q2Q A;  5A0I A;  2EWG A;  5ILH A;  5IN8 A;  4KVD A;  5DGN F;  2VF6 A;  4GA3 A;  4N9U A;  5DJR F;  3TFN A;  3N5J F;  4EA0 A;  1YYS A;  5B01 A;  3WCE A;  1UBW A;  1VG3 A;  2PS5 A;  3VJA A;  1N1Z A;  3ZMC A;  3B7L A;  1WY0 A;  2OGD A;  4QPF A;  2ZEU A;  4P0W A;  1ZW5 A;  3N1V F;  5ERO A;  1YYQ A;  4DHD A;  4NFJ F;  4RNQ A;  4E9U A;  5IL3 A;  4XQR F;  5KSX F;  3P5R A;  1HX9 A;  3VJC A;  3ZOU A;  3Q30 A;  3QKC A;  4FP4 A;  3KRP B;  5CG5 A;  5JUZ F;  5AEL A;  3WCB A;  3SAE A;  5IMN A;  3N0G A;  3KB9 A;  3G4D A;  3PH7 A;  2E8W A;  1UBY A;  5JV0 F;  3VJB A;  2E4O A;  3LOM A;  3WEJ A;  5EAS A;  1V4J A;  3IPI A;  5B0J A;  4H5D F;  5ILI A;  2E90 A;  3MZV A;  3BNX A;  1FPS A;  4GAX A;  2ONH A;  4DWG A;  2E92 A;  4RXE A;  3ZMB A;  3DYG A;  1V4E A;  1HXA A;  1VG4 A;  1YHK A;  3LEE A;  4LZ3 A;  5DJP F;  2E8U A;  1DGP A;  3PKO A;  4MC8 A;  4JYX A;  3OYR A;  4KVW A;  3LJI A;  1N1B A;  3N49 F;  3LSN A;  3S9V A;  3V1V A;  2ZCS A;  1KIY A;  3DYF A;  1JFA A;  4H5E F;  5IK6 A;  3NPR A;  3N1W F;  5DW7 A;  5JV2 F;  4LTZ A;  4LFE A;  3WEF A;  2Z7H A;  5DHI A;  3KRO B;  4OGU A;  3AQC B;  3LMD A;  4KQ5 A;  3P41 A;  4KKM A;  5ILZ A;  5AFX A;  3SDQ A;  3SDV A;  1RTR A;  3IBA A;  2Z52 A;  4NFK F;  4NUA A;  4EA1 A;  4JXY A;  5ILD A;  4QXS F;  1WL0 A;  4FJQ A;  3KRC A;  2E8V A;  1HM7 A;  3N5H F;  1WL1 A;  2E8T A;  2Z50 A;  4DXJ A;  3WCF A;  3LVS A;  3S4J A;  1N22 A;  3LGK A;  3WEK A;  1HXG A;  3VJ8 A;  5E8H A;  1N21 A;  3KRP A;  3SDT A;  2E91 A;  4OKZ A;  2QIS A;  2E8X A;  3LK5 A;  4KFA A;  5H9D A;  2AEL A;  3SDR A;  4EA2 A;  3ICK A;  3ACW A;  4ZQ8 A;  1WL2 A;  4LLT A;  4F6V A;  4KPJ A;  3RYE A;  3UCA A;  2OA6 A;  3OAC B;  5HN9 A;  1V4K A;  4F62 A;  2J1P A;  5IKA A;  4HD1 A;  3NF2 A;  5IKH A;  3WJN A;  3P8R A;  3KRA A;  2E94 A;  5DHK A;  2P1C A;  5B02 A;  2F7M F;  4PVX F;  4JZB A;  3WCM A;  3LDW A;  2H8O A;  4OMG A;  3ACX A;  5DGS F;  4K10 A;  2F89 F;  3CP6 A;  5I1U A;  3AQ0 A;  5ILJ A;  3DYH A;  2J5C A;  4XQT F;  5CG6 A;  1HM4 A;  3PYB A;  5DZ2 A;  2RAH A;  4L2X F;  4GP1 A;  3M00 A;  3ICM A;  3OAB B;  5E8L A;  4KQS A;  4NG6 A;  3KRO A;  2OPM A;  3KRF A;  2F92 F;  3LLW A;  4N1Z F;  4PVY F;  5JV1 F;  3WE9 A;  2O1O A;  5DGM F;  3RYW A;  4DI5 A;  1N23 A;  3SDU A;  4LA6 A;  3WCG A;  3WCL A;  5B03 A;  2I19 A;  3PDE A;  2J1O A;  3ADZ A;  4KWD A;  3WEG A;  3ZL6 A;  2AET A;  3PYA A;  5ILY A;  2ZCQ A;  3G4F A;  5IK9 A;  4DEM F;  4LUU A;  3P8L A;  4H5C F;  1N24 A;  4MC0 A;  2E93 A;  5IK0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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