2Z4VA

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ggpp (inhibitory site)
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
336
structure length
314
Chain Sequence
NKMEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSHGHSLVPFINLLGIIYQIRDDYLNLKDFQFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPELLYIIDHLSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Geranylgeranyl pyrophosphate synthetase
total genus 131
structure length 314
sequence length 336
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2z4vA00
3WSAA 4DI5A 1N21A 4P0WA 5B02A 3PKOA 3WSBA 4H5EF 5EATA 3SAEA 3P8LA 4OGUA 3N3DA 4RXCA 5IK9A 4RXAA 1YHLA 2Q58A 3LZ9A 4P0XA 3WEKA 5ILKA 3NPRA 1PS1A 3APZA 3WCJA 3ACYA 2Q9ZA 1RQIA 1UBXA 4FJQA 3ZL6A 2ZCSA 2Q80A 2AETA 5DZ2A 3LGKA 1V4IA 3OABB 5IK0A 3QQVA 4E9UA 3KRFB 1VG3A 4JVJF 3W7FA 1EZFA 5ILIA 3PH7A 3PYBA 5I1UA 4EA2A 4DZWA 5JV0F 4LFGA 3S4JA 3M00A 5DIQF 2E91A 5IMNA 2O1OA 4XQRF 3WJNA 3N3LF 3M0GA 5CG6A 4P0VA 3KRPB 4NFJF 5EASA 1VG2A 3CP6A 1V4JA 3ADZA 5JV1F 4E9ZA 3LSNA 4JYXA 3ICKA 3VJDA 1YYUA 3VJEA 3G4FA 3LEEA 1JFAA 4NG6A 5DGSF 2J1PA 4PVYF 3ACXA 3WJOA 2ZCRA 1HXGA 3VJCA 4KVYA 3ZMCA 2E95A 3KROA 3VJ8A 1YYSA 2E4OA 5A0KA 4LZ0A 4MC0A 4NFKF 2RAHA 3N49F 2ZCOA 3WCAA 3IBAA 3AE0A 5ILDA 3VJBA 4RNQA 3OACA 3RYWA 2Z7HA 5IMIA 4PVXF 3DYGA 5AHUB 2ZEUA 1YHMA 3N1WF 2Z4YA 2E8XA 2OPMA 3CC9A 3KRAA 3Q1OA 5A0IA 3V66A 3ZOUA 5B03A 2Z7IA 2F89F 5KSXF 4KK2A 2PS6A 4LA6A 1WL1A 4ZQ8A 4KQSA 2P1CA 3PYAA 5IKHA 5E8KA 2AZLA 5HN7A 2PS8A 4KFAA 4KPDA 2E94A 4LZCA 3LGZB 3G4DA 1WKZA 4RXEA 5IL3A 1YYRA 1WMWA 5HNAA 3Q2QA 3DYHA 1WL0A 3N46F 1WL2A 5ERMA 1YHKA 4LXWA 1N24A 2PS7A 3QKCA 3OYRA 3WJKA 3BNXA 2Z50A 5IN8A 5IM1A 3NRIA 5IL8A 3WCBA 3LVSA 4XQTF 4NKEA 4WK5A 1WL3A 3KRCA 3KB9A 1V4HA 4N9UA 2FORA 2J5CA 3SDRA 4RYPA 4F62A 3SDQA 2E8VA 5DGMF 2E8UA 4XQSF 3OABA 3LOMA 1UBVA 3WEJA 2H8OA 3KRFA 4KQ5A 4LTZA 3SDTA 5EROA 3AQ0A 5ILJA 2ONGA 1HM7A 3ID0A 3LLWA 4LOBA 4EA1A 2F92F 4JXNA 1UBWA 3B7LA 4LUUA 3LMDA 5HN8A 3WCDA 3MAVA 4OMGA 3ZMBA 4MC8A 3KBKA 3N5HF 4JXYA 4DXJA 2DH4A 1HX9A 3WC9A 1RQJA 3WCLA 2E93A 2F94F 1YJ4A 2AELA 1YYQA 2AZKA 2OPNA 3WCEA 3ZCDA 4RXDA 4Q23A 4HD1A 5B0IA 1N1ZA 3P5RA 4KUXA 1FPSA 5B0LA 5AELA 5JA0F 1YYTA 3VJ9A 3P8RA 4LFEA 1JFGA 2FTZA 4KWDA 1N22A 3WEFA 4KVDA 5DGNF 2EWGA 2Z78A 3TFPA 4F6VA 5B01A 4LZ3A 5ILZA 3RYEA 1N1BA 2PS4A 1WY0A 4OKZA 5B0MA 1DI1A 1VG4A 4N1ZF 3V1VA 4GP2A 2Z4XA 4NUAA 4F6XA 3TC1A 1V4EA 5JV2F 3TFNA 5DW7A 4KKMA 1VG6A 5DJVF 5B0JA 3ASXA 1KIZA 2ZCQA 1HXAA 1DGPA 2E92A 3P5PA 3AQBB 4KVWA 2OA6A 3EGTA 3Q2ZA 4L2XF 2E8TA 5IVGA 4DWGA 3IPIA 1N23A 3LK5A 1YQ7A 3LG5A 3M9UA 2Z52A 3WCIA 3VJAA 4JZXA 5JUZF 3P41A 2F8CF 4LTVA 3WCCA 5HN9A 3ICZA 2AZJA 3RBMA 3KRCB 2E90A 3RMGA 4NKFA 4LPGF 4KQUA 4JZBA 3NPKA 5DHIA 4LLTA 1RTRA 3ICMA 1VG7A 1HXCA 5ILYA 3UCAA 5AYPA 1HM4A 5ER8A 2Q9YA 5IK6A 3TFVA 5DJPF 3V1XA 5CG5A 4KVIA 4LFVF 5IMPA 3BNYA 3SDVA 4E1EA 3KRPA 4LA5A 3N0FA 3N1VF 4QXSF 5DJRF 3WCMA 3N6KF 2Z4WA 2OGDA 3EFQA 4LIXA 3WE9A 4LLSA 2AEKA 3KROB 3N45F 4NFIF 1KIYA 4OMHA 3EZ3A 2VF6A 2I19A 1YV5A 2Z4VA 4K10A 3SDUA 5B00A 3ICNA 2Z4ZA 3OACB 1V4KA 4DEMF 5H9DA 3LDWA 5AFXA 3N5JF 5EAUA 4DWBA 5E8LA 3KRAB 3NF2A 3WEIA 3CKEA 3M01A 2F7MF 4LPHF 3N0GA 5B0KA 5IKAA 4H5CF 3WCGA 1UBYA 3ACWA 5ILHA 3LJIA 2ONHA 5C05A 3WCHA 4UMJA 4H5DF 3DYFA 2QISA 2F9KF 2F8ZF 3PDEA 4GAXA 3TS7A 3MZVA 4OKMA 3WEHA 5DHKA 4GP1A 3WEGA 4QPFA 4DHDA 2ZEVA 4MC3A 2PS5A 2J1OA 4KPJA 4GA3A 5E8HA 5ERNA 3Q30A 1ZW5A 5A0JA 1N20A 4FP4A 3S9VA 4EA0A 2ZY1A 3AQCB 2E8WA 3M02A 3WCFA
chains in the Genus database with same CATH superfamily
3WSAA 4DI5A 1N21A 4P0WA 5B02A 3PKOA 3WSBA 4H5EF 5EATA 3SAEA 3P8LA 4OGUA 3N3DA 4RXCA 5IK9A 4RXAA 1YHLA 2Q58A 3LZ9A 4P0XA 3WEKA 5ILKA 3NPRA 1PS1A 3APZA 3WCJA 3ACYA 2Q9ZA 1RQIA 1UBXA 4FJQA 3ZL6A 2ZCSA 2Q80A 2AETA 5DZ2A 3LGKA 1V4IA 3OABB 5IK0A 3QQVA 4E9UA 3KRFB 1VG3A 4JVJF 3W7FA 1EZFA 5ILIA 3PH7A 3PYBA 5I1UA 4EA2A 4DZWA 5JV0F 4LFGA 3S4JA 3M00A 5DIQF 2E91A 5IMNA 2O1OA 4XQRF 3WJNA 3N3LF 3M0GA 5CG6A 4P0VA 3KRPB 4NFJF 5EASA 1VG2A 3CP6A 1V4JA 3ADZA 5JV1F 4E9ZA 3LSNA 4JYXA 3ICKA 3VJDA 1YYUA 3VJEA 3G4FA 3LEEA 1JFAA 4NG6A 5DGSF 2J1PA 4PVYF 3ACXA 3WJOA 2ZCRA 1HXGA 3VJCA 4KVYA 3ZMCA 2E95A 3KROA 3VJ8A 1YYSA 2E4OA 5A0KA 4LZ0A 4MC0A 4NFKF 2RAHA 3N49F 2ZCOA 3WCAA 3IBAA 3AE0A 5ILDA 3VJBA 4RNQA 3OACA 3RYWA 2Z7HA 5IMIA 4PVXF 3DYGA 5AHUB 2ZEUA 1YHMA 3N1WF 2Z4YA 2E8XA 2OPMA 3CC9A 3KRAA 3Q1OA 5A0IA 3V66A 3ZOUA 5B03A 2Z7IA 2F89F 5KSXF 4KK2A 2PS6A 4LA6A 1WL1A 4ZQ8A 4KQSA 2P1CA 3PYAA 5IKHA 5E8KA 2AZLA 5HN7A 2PS8A 4KFAA 4KPDA 2E94A 4LZCA 3LGZB 3G4DA 1WKZA 4RXEA 5IL3A 1YYRA 1WMWA 5HNAA 3Q2QA 3DYHA 1WL0A 3N46F 1WL2A 5ERMA 1YHKA 4LXWA 1N24A 2PS7A 3QKCA 3OYRA 3WJKA 3BNXA 2Z50A 5IN8A 5IM1A 3NRIA 5IL8A 3WCBA 3LVSA 4XQTF 4NKEA 4WK5A 1WL3A 3KRCA 3KB9A 1V4HA 4N9UA 2FORA 2J5CA 3SDRA 4RYPA 4F62A 3SDQA 2E8VA 5DGMF 2E8UA 4XQSF 3OABA 3LOMA 1UBVA 3WEJA 2H8OA 3KRFA 4KQ5A 4LTZA 3SDTA 5EROA 3AQ0A 5ILJA 2ONGA 1HM7A 3ID0A 3LLWA 4LOBA 4EA1A 2F92F 4JXNA 1UBWA 3B7LA 4LUUA 3LMDA 5HN8A 3WCDA 3MAVA 4OMGA 3ZMBA 4MC8A 3KBKA 3N5HF 4JXYA 4DXJA 2DH4A 1HX9A 3WC9A 1RQJA 3WCLA 2E93A 2F94F 1YJ4A 2AELA 1YYQA 2AZKA 2OPNA 3WCEA 3ZCDA 4RXDA 4Q23A 4HD1A 5B0IA 1N1ZA 3P5RA 4KUXA 1FPSA 5B0LA 5AELA 5JA0F 1YYTA 3VJ9A 3P8RA 4LFEA 1JFGA 2FTZA 4KWDA 1N22A 3WEFA 4KVDA 5DGNF 2EWGA 2Z78A 3TFPA 4F6VA 5B01A 4LZ3A 5ILZA 3RYEA 1N1BA 2PS4A 1WY0A 4OKZA 5B0MA 1DI1A 1VG4A 4N1ZF 3V1VA 4GP2A 2Z4XA 4NUAA 4F6XA 3TC1A 1V4EA 5JV2F 3TFNA 5DW7A 4KKMA 1VG6A 5DJVF 5B0JA 3ASXA 1KIZA 2ZCQA 1HXAA 1DGPA 2E92A 3P5PA 3AQBB 4KVWA 2OA6A 3EGTA 3Q2ZA 4L2XF 2E8TA 5IVGA 4DWGA 3IPIA 1N23A 3LK5A 1YQ7A 3LG5A 3M9UA 2Z52A 3WCIA 3VJAA 4JZXA 5JUZF 3P41A 2F8CF 4LTVA 3WCCA 5HN9A 3ICZA 2AZJA 3RBMA 3KRCB 2E90A 3RMGA 4NKFA 4LPGF 4KQUA 4JZBA 3NPKA 5DHIA 4LLTA 1RTRA 3ICMA 1VG7A 1HXCA 5ILYA 3UCAA 5AYPA 1HM4A 5ER8A 2Q9YA 5IK6A 3TFVA 5DJPF 3V1XA 5CG5A 4KVIA 4LFVF 5IMPA 3BNYA 3SDVA 4E1EA 3KRPA 4LA5A 3N0FA 3N1VF 4QXSF 5DJRF 3WCMA 3N6KF 2Z4WA 2OGDA 3EFQA 4LIXA 3WE9A 4LLSA 2AEKA 3KROB 3N45F 4NFIF 1KIYA 4OMHA 3EZ3A 2VF6A 2I19A 1YV5A 2Z4VA 4K10A 3SDUA 5B00A 3ICNA 2Z4ZA 3OACB 1V4KA 4DEMF 5H9DA 3LDWA 5AFXA 3N5JF 5EAUA 4DWBA 5E8LA 3KRAB 3NF2A 3WEIA 3CKEA 3M01A 2F7MF 4LPHF 3N0GA 5B0KA 5IKAA 4H5CF 3WCGA 1UBYA 3ACWA 5ILHA 3LJIA 2ONHA 5C05A 3WCHA 4UMJA 4H5DF 3DYFA 2QISA 2F9KF 2F8ZF 3PDEA 4GAXA 3TS7A 3MZVA 4OKMA 3WEHA 5DHKA 4GP1A 3WEGA 4QPFA 4DHDA 2ZEVA 4MC3A 2PS5A 2J1OA 4KPJA 4GA3A 5E8HA 5ERNA 3Q30A 1ZW5A 5A0JA 1N20A 4FP4A 3S9VA 4EA0A 2ZY1A 3AQCB 2E8WA 3M02A 3WCFA
chains in the Genus database with same CATH topology
3WSAA 4DI5A 1N21A 4P0WA 5B02A 3PKOA 3WSBA 4H5EF 5EATA 3SAEA 3P8LA 4OGUA 3N3DA 4RXCA 5IK9A 4RXAA 1YHLA 2Q58A 3LZ9A 4P0XA 3WEKA 5ILKA 3NPRA 1PS1A 3APZA 3WCJA 3ACYA 2Q9ZA 1RQIA 1UBXA 4FJQA 3ZL6A 2ZCSA 2Q80A 2AETA 5DZ2A 3LGKA 1V4IA 3OABB 5IK0A 3QQVA 4E9UA 3KRFB 1VG3A 4JVJF 3W7FA 1EZFA 5ILIA 3PH7A 3PYBA 5I1UA 4EA2A 4DZWA 5JV0F 4LFGA 3S4JA 3M00A 5DIQF 2E91A 5IMNA 2O1OA 4XQRF 3WJNA 3N3LF 3M0GA 5CG6A 4P0VA 3KRPB 4NFJF 5EASA 1VG2A 3CP6A 1V4JA 3ADZA 5JV1F 4E9ZA 3LSNA 4JYXA 3ICKA 3VJDA 1YYUA 3VJEA 3G4FA 3LEEA 1JFAA 4NG6A 5DGSF 2J1PA 4PVYF 3ACXA 3WJOA 2ZCRA 1HXGA 3VJCA 4KVYA 3ZMCA 2E95A 3KROA 3VJ8A 1YYSA 2E4OA 5A0KA 4LZ0A 4MC0A 4NFKF 2RAHA 3N49F 2ZCOA 3WCAA 3IBAA 3AE0A 5ILDA 3VJBA 4RNQA 3OACA 3RYWA 2Z7HA 5IMIA 4PVXF 3DYGA 5AHUB 2ZEUA 1YHMA 3N1WF 2Z4YA 2E8XA 2OPMA 3CC9A 3KRAA 3Q1OA 5A0IA 3V66A 3ZOUA 5B03A 2Z7IA 2F89F 5KSXF 4KK2A 2PS6A 4LA6A 1WL1A 4ZQ8A 4KQSA 2P1CA 3PYAA 5IKHA 5E8KA 2AZLA 5HN7A 2PS8A 4KFAA 4KPDA 2E94A 4LZCA 3LGZB 3G4DA 1WKZA 4RXEA 5IL3A 1YYRA 1WMWA 5HNAA 3Q2QA 3DYHA 1WL0A 3N46F 1WL2A 5ERMA 1YHKA 4LXWA 1N24A 2PS7A 3QKCA 3OYRA 3WJKA 3BNXA 2Z50A 5IN8A 5IM1A 3NRIA 5IL8A 3WCBA 3LVSA 4XQTF 4NKEA 4WK5A 1WL3A 3KRCA 3KB9A 1V4HA 4N9UA 2FORA 2J5CA 3SDRA 4RYPA 4F62A 3SDQA 2E8VA 5DGMF 2E8UA 4XQSF 3OABA 3LOMA 1UBVA 3WEJA 2H8OA 3KRFA 4KQ5A 4LTZA 3SDTA 5EROA 3AQ0A 5ILJA 2ONGA 1HM7A 3ID0A 3LLWA 4LOBA 4EA1A 2F92F 4JXNA 1UBWA 3B7LA 4LUUA 3LMDA 5HN8A 3WCDA 3MAVA 4OMGA 3ZMBA 4MC8A 3KBKA 3N5HF 4JXYA 4DXJA 2DH4A 1HX9A 3WC9A 1RQJA 3WCLA 2E93A 2F94F 1YJ4A 2AELA 1YYQA 2AZKA 2OPNA 3WCEA 3ZCDA 4RXDA 4Q23A 4HD1A 5B0IA 1N1ZA 3P5RA 4KUXA 1FPSA 5B0LA 5AELA 5JA0F 1YYTA 3VJ9A 3P8RA 4LFEA 1JFGA 2FTZA 4KWDA 1N22A 3WEFA 4KVDA 5DGNF 2EWGA 2Z78A 3TFPA 4F6VA 5B01A 4LZ3A 5ILZA 3RYEA 1N1BA 2PS4A 1WY0A 4OKZA 5B0MA 1DI1A 1VG4A 4N1ZF 3V1VA 4GP2A 2Z4XA 4NUAA 4F6XA 3TC1A 1V4EA 5JV2F 3TFNA 5DW7A 4KKMA 1VG6A 5DJVF 5B0JA 3ASXA 1KIZA 2ZCQA 1HXAA 1DGPA 2E92A 3P5PA 3AQBB 4KVWA 2OA6A 3EGTA 3Q2ZA 4L2XF 2E8TA 5IVGA 4DWGA 3IPIA 1N23A 3LK5A 1YQ7A 3LG5A 3M9UA 2Z52A 3WCIA 3VJAA 4JZXA 5JUZF 3P41A 2F8CF 4LTVA 3WCCA 5HN9A 3ICZA 2AZJA 3RBMA 3KRCB 2E90A 3RMGA 4NKFA 4LPGF 4KQUA 4JZBA 3NPKA 5DHIA 4LLTA 1RTRA 3ICMA 1VG7A 1HXCA 5ILYA 3UCAA 5AYPA 1HM4A 5ER8A 2Q9YA 5IK6A 3TFVA 5DJPF 3V1XA 5CG5A 4KVIA 4LFVF 5IMPA 3BNYA 3SDVA 4E1EA 3KRPA 4LA5A 3N0FA 3N1VF 4QXSF 5DJRF 3WCMA 3N6KF 2Z4WA 2OGDA 3EFQA 4LIXA 3WE9A 4LLSA 2AEKA 3KROB 3N45F 4NFIF 1KIYA 4OMHA 3EZ3A 2VF6A 2I19A 1YV5A 2Z4VA 4K10A 3SDUA 5B00A 3ICNA 2Z4ZA 3OACB 1V4KA 4DEMF 5H9DA 3LDWA 5AFXA 3N5JF 5EAUA 4DWBA 5E8LA 3KRAB 3NF2A 3WEIA 3CKEA 3M01A 2F7MF 4LPHF 3N0GA 5B0KA 5IKAA 4H5CF 3WCGA 1UBYA 3ACWA 5ILHA 3LJIA 2ONHA 5C05A 3WCHA 4UMJA 4H5DF 3DYFA 2QISA 2F9KF 2F8ZF 3PDEA 4GAXA 3TS7A 3MZVA 4OKMA 3WEHA 5DHKA 4GP1A 3WEGA 4QPFA 4DHDA 2ZEVA 4MC3A 2PS5A 2J1OA 4KPJA 4GA3A 5E8HA 5ERNA 3Q30A 1ZW5A 5A0JA 1N20A 4FP4A 3S9VA 4EA0A 2ZY1A 3AQCB 2E8WA 3M02A 3WCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WSA A;  4DI5 A;  1N21 A;  4P0W A;  5B02 A;  3PKO A;  3WSB A;  4H5E F;  5EAT A;  3SAE A;  3P8L A;  4OGU A;  3N3D A;  4RXC A;  5IK9 A;  4RXA A;  1YHL A;  2Q58 A;  3LZ9 A;  4P0X A;  3WEK A;  5ILK A;  3NPR A;  1PS1 A;  3APZ A;  3WCJ A;  3ACY A;  2Q9Z A;  1RQI A;  1UBX A;  4FJQ A;  3ZL6 A;  2ZCS A;  2Q80 A;  2AET A;  5DZ2 A;  3LGK A;  1V4I A;  3OAB B;  5IK0 A;  3QQV A;  4E9U A;  3KRF B;  1VG3 A;  4JVJ F;  3W7F A;  1EZF A;  5ILI A;  3PH7 A;  3PYB A;  5I1U A;  4EA2 A;  4DZW A;  5JV0 F;  4LFG A;  3S4J A;  3M00 A;  5DIQ F;  2E91 A;  5IMN A;  2O1O A;  4XQR F;  3WJN A;  3N3L F;  3M0G A;  5CG6 A;  4P0V A;  3KRP B;  4NFJ F;  5EAS A;  1VG2 A;  3CP6 A;  1V4J A;  3ADZ A;  5JV1 F;  4E9Z A;  3LSN A;  4JYX A;  3ICK A;  3VJD A;  1YYU A;  3VJE A;  3G4F A;  3LEE A;  1JFA A;  4NG6 A;  5DGS F;  2J1P A;  4PVY F;  3ACX A;  3WJO A;  2ZCR A;  1HXG A;  3VJC A;  4KVY A;  3ZMC A;  2E95 A;  3KRO A;  3VJ8 A;  1YYS A;  2E4O A;  5A0K A;  4LZ0 A;  4MC0 A;  4NFK F;  2RAH A;  3N49 F;  2ZCO A;  3WCA A;  3IBA A;  3AE0 A;  5ILD A;  3VJB A;  4RNQ A;  3OAC A;  3RYW A;  2Z7H A;  5IMI A;  4PVX F;  3DYG A;  5AHU B;  2ZEU A;  1YHM A;  3N1W F;  2Z4Y A;  2E8X A;  2OPM A;  3CC9 A;  3KRA A;  3Q1O A;  5A0I A;  3V66 A;  3ZOU A;  5B03 A;  2Z7I A;  2F89 F;  5KSX F;  4KK2 A;  2PS6 A;  4LA6 A;  1WL1 A;  4ZQ8 A;  4KQS A;  2P1C A;  3PYA A;  5IKH A;  5E8K A;  2AZL A;  5HN7 A;  2PS8 A;  4KFA A;  4KPD A;  2E94 A;  4LZC A;  3LGZ B;  3G4D A;  1WKZ A;  4RXE A;  5IL3 A;  1YYR A;  1WMW A;  5HNA A;  3Q2Q A;  3DYH A;  1WL0 A;  3N46 F;  1WL2 A;  5ERM A;  1YHK A;  4LXW A;  1N24 A;  2PS7 A;  3QKC A;  3OYR A;  3WJK A;  3BNX A;  2Z50 A;  5IN8 A;  5IM1 A;  3NRI A;  5IL8 A;  3WCB A;  3LVS A;  4XQT F;  4NKE A;  4WK5 A;  1WL3 A;  3KRC A;  3KB9 A;  1V4H A;  4N9U A;  2FOR A;  2J5C A;  3SDR A;  4RYP A;  4F62 A;  3SDQ A;  2E8V A;  5DGM F;  2E8U A;  4XQS F;  3OAB A;  3LOM A;  1UBV A;  3WEJ A;  2H8O A;  3KRF A;  4KQ5 A;  4LTZ A;  3SDT A;  5ERO A;  3AQ0 A;  5ILJ A;  2ONG A;  1HM7 A;  3ID0 A;  3LLW A;  4LOB A;  4EA1 A;  2F92 F;  4JXN A;  1UBW A;  3B7L A;  4LUU A;  3LMD A;  5HN8 A;  3WCD A;  3MAV A;  4OMG A;  3ZMB A;  4MC8 A;  3KBK A;  3N5H F;  4JXY A;  4DXJ A;  2DH4 A;  1HX9 A;  3WC9 A;  1RQJ A;  3WCL A;  2E93 A;  2F94 F;  1YJ4 A;  2AEL A;  1YYQ A;  2AZK A;  2OPN A;  3WCE A;  3ZCD A;  4RXD A;  4Q23 A;  4HD1 A;  5B0I A;  1N1Z A;  3P5R A;  4KUX A;  1FPS A;  5B0L A;  5AEL A;  5JA0 F;  1YYT A;  3VJ9 A;  3P8R A;  4LFE A;  1JFG A;  2FTZ A;  4KWD A;  1N22 A;  3WEF A;  4KVD A;  5DGN F;  2EWG A;  2Z78 A;  3TFP A;  4F6V A;  5B01 A;  4LZ3 A;  5ILZ A;  3RYE A;  1N1B A;  2PS4 A;  1WY0 A;  4OKZ A;  5B0M A;  1DI1 A;  1VG4 A;  4N1Z F;  3V1V A;  4GP2 A;  2Z4X A;  4NUA A;  4F6X A;  3TC1 A;  1V4E A;  5JV2 F;  3TFN A;  5DW7 A;  4KKM A;  1VG6 A;  5DJV F;  5B0J A;  3ASX A;  1KIZ A;  2ZCQ A;  1HXA A;  1DGP A;  2E92 A;  3P5P A;  3AQB B;  4KVW A;  2OA6 A;  3EGT A;  3Q2Z A;  4L2X F;  2E8T A;  5IVG A;  4DWG A;  3IPI A;  1N23 A;  3LK5 A;  1YQ7 A;  3LG5 A;  3M9U A;  2Z52 A;  3WCI A;  3VJA A;  4JZX A;  5JUZ F;  3P41 A;  2F8C F;  4LTV A;  3WCC A;  5HN9 A;  3ICZ A;  2AZJ A;  3RBM A;  3KRC B;  2E90 A;  3RMG A;  4NKF A;  4LPG F;  4KQU A;  4JZB A;  3NPK A;  5DHI A;  4LLT A;  1RTR A;  3ICM A;  1VG7 A;  1HXC A;  5ILY A;  3UCA A;  5AYP A;  1HM4 A;  5ER8 A;  2Q9Y A;  5IK6 A;  3TFV A;  5DJP F;  3V1X A;  5CG5 A;  4KVI A;  4LFV F;  5IMP A;  3BNY A;  3SDV A;  4E1E A;  3KRP A;  4LA5 A;  3N0F A;  3N1V F;  4QXS F;  5DJR F;  3WCM A;  3N6K F;  2Z4W A;  2OGD A;  3EFQ A;  4LIX A;  3WE9 A;  4LLS A;  2AEK A;  3KRO B;  3N45 F;  4NFI F;  1KIY A;  4OMH A;  3EZ3 A;  2VF6 A;  2I19 A;  1YV5 A;  2Z4V A;  4K10 A;  3SDU A;  5B00 A;  3ICN A;  2Z4Z A;  3OAC B;  1V4K A;  4DEM F;  5H9D A;  3LDW A;  5AFX A;  3N5J F;  5EAU A;  4DWB A;  5E8L A;  3KRA B;  3NF2 A;  3WEI A;  3CKE A;  3M01 A;  2F7M F;  4LPH F;  3N0G A;  5B0K A;  5IKA A;  4H5C F;  3WCG A;  1UBY A;  3ACW A;  5ILH A;  3LJI A;  2ONH A;  5C05 A;  3WCH A;  4UMJ A;  4H5D F;  3DYF A;  2QIS A;  2F9K F;  2F8Z F;  3PDE A;  4GAX A;  3TS7 A;  3MZV A;  4OKM A;  3WEH A;  5DHK A;  4GP1 A;  3WEG A;  4QPF A;  4DHD A;  2ZEV A;  4MC3 A;  2PS5 A;  2J1O A;  4KPJ A;  4GA3 A;  5E8H A;  5ERN A;  3Q30 A;  1ZW5 A;  5A0J A;  1N20 A;  4FP4 A;  3S9V A;  4EA0 A;  2ZY1 A;  3AQC B;  2E8W A;  3M02 A;  3WCF A; 
#chains in the Genus database with same CATH topology
 3WSA A;  4DI5 A;  1N21 A;  4P0W A;  5B02 A;  3PKO A;  3WSB A;  4H5E F;  5EAT A;  3SAE A;  3P8L A;  4OGU A;  3N3D A;  4RXC A;  5IK9 A;  4RXA A;  1YHL A;  2Q58 A;  3LZ9 A;  4P0X A;  3WEK A;  5ILK A;  3NPR A;  1PS1 A;  3APZ A;  3WCJ A;  3ACY A;  2Q9Z A;  1RQI A;  1UBX A;  4FJQ A;  3ZL6 A;  2ZCS A;  2Q80 A;  2AET A;  5DZ2 A;  3LGK A;  1V4I A;  3OAB B;  5IK0 A;  3QQV A;  4E9U A;  3KRF B;  1VG3 A;  4JVJ F;  3W7F A;  1EZF A;  5ILI A;  3PH7 A;  3PYB A;  5I1U A;  4EA2 A;  4DZW A;  5JV0 F;  4LFG A;  3S4J A;  3M00 A;  5DIQ F;  2E91 A;  5IMN A;  2O1O A;  4XQR F;  3WJN A;  3N3L F;  3M0G A;  5CG6 A;  4P0V A;  3KRP B;  4NFJ F;  5EAS A;  1VG2 A;  3CP6 A;  1V4J A;  3ADZ A;  5JV1 F;  4E9Z A;  3LSN A;  4JYX A;  3ICK A;  3VJD A;  1YYU A;  3VJE A;  3G4F A;  3LEE A;  1JFA A;  4NG6 A;  5DGS F;  2J1P A;  4PVY F;  3ACX A;  3WJO A;  2ZCR A;  1HXG A;  3VJC A;  4KVY A;  3ZMC A;  2E95 A;  3KRO A;  3VJ8 A;  1YYS A;  2E4O A;  5A0K A;  4LZ0 A;  4MC0 A;  4NFK F;  2RAH A;  3N49 F;  2ZCO A;  3WCA A;  3IBA A;  3AE0 A;  5ILD A;  3VJB A;  4RNQ A;  3OAC A;  3RYW A;  2Z7H A;  5IMI A;  4PVX F;  3DYG A;  5AHU B;  2ZEU A;  1YHM A;  3N1W F;  2Z4Y A;  2E8X A;  2OPM A;  3CC9 A;  3KRA A;  3Q1O A;  5A0I A;  3V66 A;  3ZOU A;  5B03 A;  2Z7I A;  2F89 F;  5KSX F;  4KK2 A;  2PS6 A;  4LA6 A;  1WL1 A;  4ZQ8 A;  4KQS A;  2P1C A;  3PYA A;  5IKH A;  5E8K A;  2AZL A;  5HN7 A;  2PS8 A;  4KFA A;  4KPD A;  2E94 A;  4LZC A;  3LGZ B;  3G4D A;  1WKZ A;  4RXE A;  5IL3 A;  1YYR A;  1WMW A;  5HNA A;  3Q2Q A;  3DYH A;  1WL0 A;  3N46 F;  1WL2 A;  5ERM A;  1YHK A;  4LXW A;  1N24 A;  2PS7 A;  3QKC A;  3OYR A;  3WJK A;  3BNX A;  2Z50 A;  5IN8 A;  5IM1 A;  3NRI A;  5IL8 A;  3WCB A;  3LVS A;  4XQT F;  4NKE A;  4WK5 A;  1WL3 A;  3KRC A;  3KB9 A;  1V4H A;  4N9U A;  2FOR A;  2J5C A;  3SDR A;  4RYP A;  4F62 A;  3SDQ A;  2E8V A;  5DGM F;  2E8U A;  4XQS F;  3OAB A;  3LOM A;  1UBV A;  3WEJ A;  2H8O A;  3KRF A;  4KQ5 A;  4LTZ A;  3SDT A;  5ERO A;  3AQ0 A;  5ILJ A;  2ONG A;  1HM7 A;  3ID0 A;  3LLW A;  4LOB A;  4EA1 A;  2F92 F;  4JXN A;  1UBW A;  3B7L A;  4LUU A;  3LMD A;  5HN8 A;  3WCD A;  3MAV A;  4OMG A;  3ZMB A;  4MC8 A;  3KBK A;  3N5H F;  4JXY A;  4DXJ A;  2DH4 A;  1HX9 A;  3WC9 A;  1RQJ A;  3WCL A;  2E93 A;  2F94 F;  1YJ4 A;  2AEL A;  1YYQ A;  2AZK A;  2OPN A;  3WCE A;  3ZCD A;  4RXD A;  4Q23 A;  4HD1 A;  5B0I A;  1N1Z A;  3P5R A;  4KUX A;  1FPS A;  5B0L A;  5AEL A;  5JA0 F;  1YYT A;  3VJ9 A;  3P8R A;  4LFE A;  1JFG A;  2FTZ A;  4KWD A;  1N22 A;  3WEF A;  4KVD A;  5DGN F;  2EWG A;  2Z78 A;  3TFP A;  4F6V A;  5B01 A;  4LZ3 A;  5ILZ A;  3RYE A;  1N1B A;  2PS4 A;  1WY0 A;  4OKZ A;  5B0M A;  1DI1 A;  1VG4 A;  4N1Z F;  3V1V A;  4GP2 A;  2Z4X A;  4NUA A;  4F6X A;  3TC1 A;  1V4E A;  5JV2 F;  3TFN A;  5DW7 A;  4KKM A;  1VG6 A;  5DJV F;  5B0J A;  3ASX A;  1KIZ A;  2ZCQ A;  1HXA A;  1DGP A;  2E92 A;  3P5P A;  3AQB B;  4KVW A;  2OA6 A;  3EGT A;  3Q2Z A;  4L2X F;  2E8T A;  5IVG A;  4DWG A;  3IPI A;  1N23 A;  3LK5 A;  1YQ7 A;  3LG5 A;  3M9U A;  2Z52 A;  3WCI A;  3VJA A;  4JZX A;  5JUZ F;  3P41 A;  2F8C F;  4LTV A;  3WCC A;  5HN9 A;  3ICZ A;  2AZJ A;  3RBM A;  3KRC B;  2E90 A;  3RMG A;  4NKF A;  4LPG F;  4KQU A;  4JZB A;  3NPK A;  5DHI A;  4LLT A;  1RTR A;  3ICM A;  1VG7 A;  1HXC A;  5ILY A;  3UCA A;  5AYP A;  1HM4 A;  5ER8 A;  2Q9Y A;  5IK6 A;  3TFV A;  5DJP F;  3V1X A;  5CG5 A;  4KVI A;  4LFV F;  5IMP A;  3BNY A;  3SDV A;  4E1E A;  3KRP A;  4LA5 A;  3N0F A;  3N1V F;  4QXS F;  5DJR F;  3WCM A;  3N6K F;  2Z4W A;  2OGD A;  3EFQ A;  4LIX A;  3WE9 A;  4LLS A;  2AEK A;  3KRO B;  3N45 F;  4NFI F;  1KIY A;  4OMH A;  3EZ3 A;  2VF6 A;  2I19 A;  1YV5 A;  2Z4V A;  4K10 A;  3SDU A;  5B00 A;  3ICN A;  2Z4Z A;  3OAC B;  1V4K A;  4DEM F;  5H9D A;  3LDW A;  5AFX A;  3N5J F;  5EAU A;  4DWB A;  5E8L A;  3KRA B;  3NF2 A;  3WEI A;  3CKE A;  3M01 A;  2F7M F;  4LPH F;  3N0G A;  5B0K A;  5IKA A;  4H5C F;  3WCG A;  1UBY A;  3ACW A;  5ILH A;  3LJI A;  2ONH A;  5C05 A;  3WCH A;  4UMJ A;  4H5D F;  3DYF A;  2QIS A;  2F9K F;  2F8Z F;  3PDE A;  4GAX A;  3TS7 A;  3MZV A;  4OKM A;  3WEH A;  5DHK A;  4GP1 A;  3WEG A;  4QPF A;  4DHD A;  2ZEV A;  4MC3 A;  2PS5 A;  2J1O A;  4KPJ A;  4GA3 A;  5E8H A;  5ERN A;  3Q30 A;  1ZW5 A;  5A0J A;  1N20 A;  4FP4 A;  3S9V A;  4EA0 A;  2ZY1 A;  3AQC B;  2E8W A;  3M02 A;  3WCF A; 
#chains in the Genus database with same CATH homology
 3WSA A;  4DI5 A;  1N21 A;  4P0W A;  5B02 A;  3PKO A;  3WSB A;  4H5E F;  5EAT A;  3SAE A;  3P8L A;  4OGU A;  3N3D A;  4RXC A;  5IK9 A;  4RXA A;  1YHL A;  2Q58 A;  3LZ9 A;  4P0X A;  3WEK A;  5ILK A;  3NPR A;  1PS1 A;  3APZ A;  3WCJ A;  3ACY A;  2Q9Z A;  1RQI A;  1UBX A;  4FJQ A;  3ZL6 A;  2ZCS A;  2Q80 A;  2AET A;  5DZ2 A;  3LGK A;  1V4I A;  3OAB B;  5IK0 A;  3QQV A;  4E9U A;  3KRF B;  1VG3 A;  4JVJ F;  3W7F A;  1EZF A;  5ILI A;  3PH7 A;  3PYB A;  5I1U A;  4EA2 A;  4DZW A;  5JV0 F;  4LFG A;  3S4J A;  3M00 A;  5DIQ F;  2E91 A;  5IMN A;  2O1O A;  4XQR F;  3WJN A;  3N3L F;  3M0G A;  5CG6 A;  4P0V A;  3KRP B;  4NFJ F;  5EAS A;  1VG2 A;  3CP6 A;  1V4J A;  3ADZ A;  5JV1 F;  4E9Z A;  3LSN A;  4JYX A;  3ICK A;  3VJD A;  1YYU A;  3VJE A;  3G4F A;  3LEE A;  1JFA A;  4NG6 A;  5DGS F;  2J1P A;  4PVY F;  3ACX A;  3WJO A;  2ZCR A;  1HXG A;  3VJC A;  4KVY A;  3ZMC A;  2E95 A;  3KRO A;  3VJ8 A;  1YYS A;  2E4O A;  5A0K A;  4LZ0 A;  4MC0 A;  4NFK F;  2RAH A;  3N49 F;  2ZCO A;  3WCA A;  3IBA A;  3AE0 A;  5ILD A;  3VJB A;  4RNQ A;  3OAC A;  3RYW A;  2Z7H A;  5IMI A;  4PVX F;  3DYG A;  5AHU B;  2ZEU A;  1YHM A;  3N1W F;  2Z4Y A;  2E8X A;  2OPM A;  3CC9 A;  3KRA A;  3Q1O A;  5A0I A;  3V66 A;  3ZOU A;  5B03 A;  2Z7I A;  2F89 F;  5KSX F;  4KK2 A;  2PS6 A;  4LA6 A;  1WL1 A;  4ZQ8 A;  4KQS A;  2P1C A;  3PYA A;  5IKH A;  5E8K A;  2AZL A;  5HN7 A;  2PS8 A;  4KFA A;  4KPD A;  2E94 A;  4LZC A;  3LGZ B;  3G4D A;  1WKZ A;  4RXE A;  5IL3 A;  1YYR A;  1WMW A;  5HNA A;  3Q2Q A;  3DYH A;  1WL0 A;  3N46 F;  1WL2 A;  5ERM A;  1YHK A;  4LXW A;  1N24 A;  2PS7 A;  3QKC A;  3OYR A;  3WJK A;  3BNX A;  2Z50 A;  5IN8 A;  5IM1 A;  3NRI A;  5IL8 A;  3WCB A;  3LVS A;  4XQT F;  4NKE A;  4WK5 A;  1WL3 A;  3KRC A;  3KB9 A;  1V4H A;  4N9U A;  2FOR A;  2J5C A;  3SDR A;  4RYP A;  4F62 A;  3SDQ A;  2E8V A;  5DGM F;  2E8U A;  4XQS F;  3OAB A;  3LOM A;  1UBV A;  3WEJ A;  2H8O A;  3KRF A;  4KQ5 A;  4LTZ A;  3SDT A;  5ERO A;  3AQ0 A;  5ILJ A;  2ONG A;  1HM7 A;  3ID0 A;  3LLW A;  4LOB A;  4EA1 A;  2F92 F;  4JXN A;  1UBW A;  3B7L A;  4LUU A;  3LMD A;  5HN8 A;  3WCD A;  3MAV A;  4OMG A;  3ZMB A;  4MC8 A;  3KBK A;  3N5H F;  4JXY A;  4DXJ A;  2DH4 A;  1HX9 A;  3WC9 A;  1RQJ A;  3WCL A;  2E93 A;  2F94 F;  1YJ4 A;  2AEL A;  1YYQ A;  2AZK A;  2OPN A;  3WCE A;  3ZCD A;  4RXD A;  4Q23 A;  4HD1 A;  5B0I A;  1N1Z A;  3P5R A;  4KUX A;  1FPS A;  5B0L A;  5AEL A;  5JA0 F;  1YYT A;  3VJ9 A;  3P8R A;  4LFE A;  1JFG A;  2FTZ A;  4KWD A;  1N22 A;  3WEF A;  4KVD A;  5DGN F;  2EWG A;  2Z78 A;  3TFP A;  4F6V A;  5B01 A;  4LZ3 A;  5ILZ A;  3RYE A;  1N1B A;  2PS4 A;  1WY0 A;  4OKZ A;  5B0M A;  1DI1 A;  1VG4 A;  4N1Z F;  3V1V A;  4GP2 A;  2Z4X A;  4NUA A;  4F6X A;  3TC1 A;  1V4E A;  5JV2 F;  3TFN A;  5DW7 A;  4KKM A;  1VG6 A;  5DJV F;  5B0J A;  3ASX A;  1KIZ A;  2ZCQ A;  1HXA A;  1DGP A;  2E92 A;  3P5P A;  3AQB B;  4KVW A;  2OA6 A;  3EGT A;  3Q2Z A;  4L2X F;  2E8T A;  5IVG A;  4DWG A;  3IPI A;  1N23 A;  3LK5 A;  1YQ7 A;  3LG5 A;  3M9U A;  2Z52 A;  3WCI A;  3VJA A;  4JZX A;  5JUZ F;  3P41 A;  2F8C F;  4LTV A;  3WCC A;  5HN9 A;  3ICZ A;  2AZJ A;  3RBM A;  3KRC B;  2E90 A;  3RMG A;  4NKF A;  4LPG F;  4KQU A;  4JZB A;  3NPK A;  5DHI A;  4LLT A;  1RTR A;  3ICM A;  1VG7 A;  1HXC A;  5ILY A;  3UCA A;  5AYP A;  1HM4 A;  5ER8 A;  2Q9Y A;  5IK6 A;  3TFV A;  5DJP F;  3V1X A;  5CG5 A;  4KVI A;  4LFV F;  5IMP A;  3BNY A;  3SDV A;  4E1E A;  3KRP A;  4LA5 A;  3N0F A;  3N1V F;  4QXS F;  5DJR F;  3WCM A;  3N6K F;  2Z4W A;  2OGD A;  3EFQ A;  4LIX A;  3WE9 A;  4LLS A;  2AEK A;  3KRO B;  3N45 F;  4NFI F;  1KIY A;  4OMH A;  3EZ3 A;  2VF6 A;  2I19 A;  1YV5 A;  2Z4V A;  4K10 A;  3SDU A;  5B00 A;  3ICN A;  2Z4Z A;  3OAC B;  1V4K A;  4DEM F;  5H9D A;  3LDW A;  5AFX A;  3N5J F;  5EAU A;  4DWB A;  5E8L A;  3KRA B;  3NF2 A;  3WEI A;  3CKE A;  3M01 A;  2F7M F;  4LPH F;  3N0G A;  5B0K A;  5IKA A;  4H5C F;  3WCG A;  1UBY A;  3ACW A;  5ILH A;  3LJI A;  2ONH A;  5C05 A;  3WCH A;  4UMJ A;  4H5D F;  3DYF A;  2QIS A;  2F9K F;  2F8Z F;  3PDE A;  4GAX A;  3TS7 A;  3MZV A;  4OKM A;  3WEH A;  5DHK A;  4GP1 A;  3WEG A;  4QPF A;  4DHD A;  2ZEV A;  4MC3 A;  2PS5 A;  2J1O A;  4KPJ A;  4GA3 A;  5E8H A;  5ERN A;  3Q30 A;  1ZW5 A;  5A0J A;  1N20 A;  4FP4 A;  3S9V A;  4EA0 A;  2ZY1 A;  3AQC B;  2E8W A;  3M02 A;  3WCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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