2Z4YA

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-252
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
304
structure length
291
Chain Sequence
NKMEAKIDELINNDPVWSSQNESLISKPYNHILLKPGRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSLVPFINLLGIIYQIRDDYLNLKDFQKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Saccharomyces cerevisiae
molecule keywords Geranylgeranyl pyrophosphate synthetase
total genus 124
structure length 291
sequence length 304
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2z4yA00
4OKMA 2FORA 3KROA 5ILDA 3VJDA 5DJRF 2EWGA 4H5EF 1HX9A 3LVSA 2P1CA 3OABA 5DHIA 4DI5A 2AZJA 2I19A 5E8HA 1N23A 4GAXA 2E8TA 3N5JF 3WCEA 4LLSA 2Q9ZA 3OACB 5IVGA 4WK5A 3OACA 1N24A 3SDRA 5EASA 3TFNA 3N5HF 3WCMA 1UBYA 3M01A 3QKCA 1UBVA 3WCAA 1YQ7A 3NRIA 3ICNA 2ONHA 5B01A 5IKAA 4FJQA 3WEFA 3VJCA 3Q30A 5AYPA 2H8OA 3W7FA 3WEHA 3PKOA 5IMIA 2Z78A 3N46F 2O1OA 3N0GA 5JV0F 4KKMA 3ASXA 4KVYA 2Z4WA 2ZY1A 5ERMA 5AHUB 5B02A 1VG6A 1V4KA 2E91A 4RXDA 4OKZA 5B0JA 1V4IA 3S9VA 2E4OA 1N1ZA 3ICMA 3APZA 1HXCA 3ID0A 3OYRA 2ZEVA 1WL2A 4UMJA 4KWDA 4DHDA 4KUXA 5DHKA 5EATA 1PS1A 1RQJA 5HN7A 4ZQ8A 4LXWA 3KRFB 3KRFA 1YYUA 4KQUA 3WCLA 3IBAA 3WCDA 3WCGA 4FP4A 3B7LA 5IK6A 3RBMA 5DJVF 3N45F 3LZ9A 3S4JA 1YHLA 1N22A 2ONGA 2F8ZF 5E8LA 3VJAA 3P8LA 3WCHA 4EA1A 4DZWA 1VG2A 3VJ8A 3SDTA 2VF6A 1UBXA 3AQBB 3WEIA 5ILKA 3KROB 3LGKA 5B0KA 1YYSA 2F94F 3WJKA 1YHMA 3IPIA 2Z7IA 4DWBA 4N1ZF 4QXSF 4K10A 3OABB 4Q23A 5IK0A 2RAHA 3P8RA 3KB9A 3WEKA 1RTRA 2PS5A 3AQCB 1VG3A 3LK5A 4DWGA 2E8WA 5AELA 3LJIA 3AE0A 3KRPA 4N9UA 2PS7A 2QISA 4KK2A 5ILZA 4H5CF 5A0KA 4PVYF 2AEKA 5E8KA 4HD1A 3TS7A 1WY0A 3ICKA 2J1OA 3M9UA 5A0IA 5DW7A 3LDWA 4LA5A 1HXAA 3LSNA 2F89F 2PS4A 5EROA 4JZBA 4GP1A 5JA0F 1N1BA 3N0FA 2F7MF 5H9DA 4F6XA 4OMHA 4LUUA 2E93A 1ZW5A 4KPJA 3KRAB 3RYEA 3WCFA 5IMNA 3KRAA 3ZL6A 1HXGA 4GP2A 3WCCA 2OPMA 1KIYA 3LLWA 4NFIF 3V1XA 1JFAA 2OGDA 5B03A 3WCIA 5HNAA 4E9UA 1YYQA 2ZEUA 4KVDA 3LG5A 5DIQF 5ILYA 3WCBA 4RNQA 3EZ3A 2ZCRA 3TFVA 2F8CF 2OPNA 4LZ0A 2E94A 5EAUA 3M0GA 1YHKA 3V66A 4EA2A 2E8XA 3ZMCA 3G4FA 4LFVF 3TFPA 2Q80A 4MC8A 2Z7HA 3Q1OA 4LIXA 1JFGA 3TC1A 5A0JA 3CP6A 1WL3A 4OMGA 3LGZB 5HN9A 5JV2F 3ADZA 3NF2A 3SDUA 3WE9A 4NG6A 1YYTA 4DEMF 3DYGA 3EFQA 2AZKA 2Z52A 4F62A 5DZ2A 3WC9A 2E90A 4NFJF 4MC0A 2Z4ZA 2Z4XA 3BNYA 3LEEA 5IKHA 1WL0A 4XQSF 5HN8A 5B00A 2J5CA 4NKFA 4P0XA 3UCAA 4P0VA 1WKZA 4RXEA 2Q9YA 3LMDA 3V1VA 1N21A 4LFGA 3SAEA 3ZOUA 4OGUA 1HM7A 2ZCOA 4LPHF 3N49F 5KSXF 5DJPF 5ILIA 5DGNF 4KQSA 1EZFA 4LA6A 3VJEA 3N3DA 4NUAA 2Q58A 2F92F 3G4DA 3P5PA 2PS6A 3ACXA 3KRPB 5ILHA 5AFXA 5DGMF 4JVJF 4XQRF 3N1VF 4LZ3A 2AELA 3ZMBA 2Z50A 3KBKA 3MAVA 4NKEA 4KQ5A 3WSBA 4E9ZA 4QPFA 2ZCSA 5C05A 5IK9A 4KFAA 3M00A 1YV5A 4E1EA 5JUZF 4KPDA 1UBWA 1FPSA 1RQIA 2F9KF 1YYRA 4RXAA 4LZCA 5IL8A 2AZLA 4DXJA 3LOMA 3Q2ZA 1WL1A 4XQTF 3BNXA 1DGPA 5JV1F 4KVWA 4P0WA 3WCJA 5ER8A 3EGTA 3CKEA 5B0MA 5IM1A 4JXYA 4LPGF 3WJOA 2OA6A 5CG6A 3ICZA 3N3LF 3QQVA 3PH7A 3P5RA 1V4HA 2E92A 4KVIA 4NFKF 5IMPA 1KIZA 4JYXA 4LTVA 3ACWA 3NPRA 5ERNA 3WJNA 4LLTA 3PDEA 5ILJA 4L2XF 2E95A 3VJ9A 5IL3A 3CC9A 4JZXA 2PS8A 3RYWA 3WEJA 2DH4A 1V4EA 1V4JA 2FTZA 4F6VA 3WEGA 3SDQA 1HM4A 2AETA 3Q2QA 3SDVA 2E8VA 2J1PA 3RMGA 2E8UA 5CG5A 1YJ4A 3N1WF 3DYFA 4JXNA 3M02A 4LFEA 1VG4A 3ACYA 4RYPA 3PYAA 4PVXF 5B0IA 3N6KF 5DGSF 4H5DF 1DI1A 3P41A 1VG7A 3WSAA 3ZCDA 2Z4VA 1WMWA 3DYHA 4GA3A 5B0LA 4LTZA 5I1UA 2Z4YA 3MZVA 3AQ0A 4LOBA 4RXCA 3VJBA 1N20A 3PYBA 4MC3A 5IN8A 4EA0A 3KRCB 3NPKA 3KRCA 2ZCQA
chains in the Genus database with same CATH superfamily
4OKMA 2FORA 3KROA 5ILDA 3VJDA 5DJRF 2EWGA 4H5EF 1HX9A 3LVSA 2P1CA 3OABA 5DHIA 4DI5A 2AZJA 2I19A 5E8HA 1N23A 4GAXA 2E8TA 3N5JF 3WCEA 4LLSA 2Q9ZA 3OACB 5IVGA 4WK5A 3OACA 1N24A 3SDRA 5EASA 3TFNA 3N5HF 3WCMA 1UBYA 3M01A 3QKCA 1UBVA 3WCAA 1YQ7A 3NRIA 3ICNA 2ONHA 5B01A 5IKAA 4FJQA 3WEFA 3VJCA 3Q30A 5AYPA 2H8OA 3W7FA 3WEHA 3PKOA 5IMIA 2Z78A 3N46F 2O1OA 3N0GA 5JV0F 4KKMA 3ASXA 4KVYA 2Z4WA 2ZY1A 5ERMA 5AHUB 5B02A 1VG6A 1V4KA 2E91A 4RXDA 4OKZA 5B0JA 1V4IA 3S9VA 2E4OA 1N1ZA 3ICMA 3APZA 1HXCA 3ID0A 3OYRA 2ZEVA 1WL2A 4UMJA 4KWDA 4DHDA 4KUXA 5DHKA 5EATA 1PS1A 1RQJA 5HN7A 4ZQ8A 4LXWA 3KRFB 3KRFA 1YYUA 4KQUA 3WCLA 3IBAA 3WCDA 3WCGA 4FP4A 3B7LA 5IK6A 3RBMA 5DJVF 3N45F 3LZ9A 3S4JA 1YHLA 1N22A 2ONGA 2F8ZF 5E8LA 3VJAA 3P8LA 3WCHA 4EA1A 4DZWA 1VG2A 3VJ8A 3SDTA 2VF6A 1UBXA 3AQBB 3WEIA 5ILKA 3KROB 3LGKA 5B0KA 1YYSA 2F94F 3WJKA 1YHMA 3IPIA 2Z7IA 4DWBA 4N1ZF 4QXSF 4K10A 3OABB 4Q23A 5IK0A 2RAHA 3P8RA 3KB9A 3WEKA 1RTRA 2PS5A 3AQCB 1VG3A 3LK5A 4DWGA 2E8WA 5AELA 3LJIA 3AE0A 3KRPA 4N9UA 2PS7A 2QISA 4KK2A 5ILZA 4H5CF 5A0KA 4PVYF 2AEKA 5E8KA 4HD1A 3TS7A 1WY0A 3ICKA 2J1OA 3M9UA 5A0IA 5DW7A 3LDWA 4LA5A 1HXAA 3LSNA 2F89F 2PS4A 5EROA 4JZBA 4GP1A 5JA0F 1N1BA 3N0FA 2F7MF 5H9DA 4F6XA 4OMHA 4LUUA 2E93A 1ZW5A 4KPJA 3KRAB 3RYEA 3WCFA 5IMNA 3KRAA 3ZL6A 1HXGA 4GP2A 3WCCA 2OPMA 1KIYA 3LLWA 4NFIF 3V1XA 1JFAA 2OGDA 5B03A 3WCIA 5HNAA 4E9UA 1YYQA 2ZEUA 4KVDA 3LG5A 5DIQF 5ILYA 3WCBA 4RNQA 3EZ3A 2ZCRA 3TFVA 2F8CF 2OPNA 4LZ0A 2E94A 5EAUA 3M0GA 1YHKA 3V66A 4EA2A 2E8XA 3ZMCA 3G4FA 4LFVF 3TFPA 2Q80A 4MC8A 2Z7HA 3Q1OA 4LIXA 1JFGA 3TC1A 5A0JA 3CP6A 1WL3A 4OMGA 3LGZB 5HN9A 5JV2F 3ADZA 3NF2A 3SDUA 3WE9A 4NG6A 1YYTA 4DEMF 3DYGA 3EFQA 2AZKA 2Z52A 4F62A 5DZ2A 3WC9A 2E90A 4NFJF 4MC0A 2Z4ZA 2Z4XA 3BNYA 3LEEA 5IKHA 1WL0A 4XQSF 5HN8A 5B00A 2J5CA 4NKFA 4P0XA 3UCAA 4P0VA 1WKZA 4RXEA 2Q9YA 3LMDA 3V1VA 1N21A 4LFGA 3SAEA 3ZOUA 4OGUA 1HM7A 2ZCOA 4LPHF 3N49F 5KSXF 5DJPF 5ILIA 5DGNF 4KQSA 1EZFA 4LA6A 3VJEA 3N3DA 4NUAA 2Q58A 2F92F 3G4DA 3P5PA 2PS6A 3ACXA 3KRPB 5ILHA 5AFXA 5DGMF 4JVJF 4XQRF 3N1VF 4LZ3A 2AELA 3ZMBA 2Z50A 3KBKA 3MAVA 4NKEA 4KQ5A 3WSBA 4E9ZA 4QPFA 2ZCSA 5C05A 5IK9A 4KFAA 3M00A 1YV5A 4E1EA 5JUZF 4KPDA 1UBWA 1FPSA 1RQIA 2F9KF 1YYRA 4RXAA 4LZCA 5IL8A 2AZLA 4DXJA 3LOMA 3Q2ZA 1WL1A 4XQTF 3BNXA 1DGPA 5JV1F 4KVWA 4P0WA 3WCJA 5ER8A 3EGTA 3CKEA 5B0MA 5IM1A 4JXYA 4LPGF 3WJOA 2OA6A 5CG6A 3ICZA 3N3LF 3QQVA 3PH7A 3P5RA 1V4HA 2E92A 4KVIA 4NFKF 5IMPA 1KIZA 4JYXA 4LTVA 3ACWA 3NPRA 5ERNA 3WJNA 4LLTA 3PDEA 5ILJA 4L2XF 2E95A 3VJ9A 5IL3A 3CC9A 4JZXA 2PS8A 3RYWA 3WEJA 2DH4A 1V4EA 1V4JA 2FTZA 4F6VA 3WEGA 3SDQA 1HM4A 2AETA 3Q2QA 3SDVA 2E8VA 2J1PA 3RMGA 2E8UA 5CG5A 1YJ4A 3N1WF 3DYFA 4JXNA 3M02A 4LFEA 1VG4A 3ACYA 4RYPA 3PYAA 4PVXF 5B0IA 3N6KF 5DGSF 4H5DF 1DI1A 3P41A 1VG7A 3WSAA 3ZCDA 2Z4VA 1WMWA 3DYHA 4GA3A 5B0LA 4LTZA 5I1UA 2Z4YA 3MZVA 3AQ0A 4LOBA 4RXCA 3VJBA 1N20A 3PYBA 4MC3A 5IN8A 4EA0A 3KRCB 3NPKA 3KRCA 2ZCQA
chains in the Genus database with same CATH topology
4OKMA 2FORA 3KROA 5ILDA 3VJDA 5DJRF 2EWGA 4H5EF 1HX9A 3LVSA 2P1CA 3OABA 5DHIA 4DI5A 2AZJA 2I19A 5E8HA 1N23A 4GAXA 2E8TA 3N5JF 3WCEA 4LLSA 2Q9ZA 3OACB 5IVGA 4WK5A 3OACA 1N24A 3SDRA 5EASA 3TFNA 3N5HF 3WCMA 1UBYA 3M01A 3QKCA 1UBVA 3WCAA 1YQ7A 3NRIA 3ICNA 2ONHA 5B01A 5IKAA 4FJQA 3WEFA 3VJCA 3Q30A 5AYPA 2H8OA 3W7FA 3WEHA 3PKOA 5IMIA 2Z78A 3N46F 2O1OA 3N0GA 5JV0F 4KKMA 3ASXA 4KVYA 2Z4WA 2ZY1A 5ERMA 5AHUB 5B02A 1VG6A 1V4KA 2E91A 4RXDA 4OKZA 5B0JA 1V4IA 3S9VA 2E4OA 1N1ZA 3ICMA 3APZA 1HXCA 3ID0A 3OYRA 2ZEVA 1WL2A 4UMJA 4KWDA 4DHDA 4KUXA 5DHKA 5EATA 1PS1A 1RQJA 5HN7A 4ZQ8A 4LXWA 3KRFB 3KRFA 1YYUA 4KQUA 3WCLA 3IBAA 3WCDA 3WCGA 4FP4A 3B7LA 5IK6A 3RBMA 5DJVF 3N45F 3LZ9A 3S4JA 1YHLA 1N22A 2ONGA 2F8ZF 5E8LA 3VJAA 3P8LA 3WCHA 4EA1A 4DZWA 1VG2A 3VJ8A 3SDTA 2VF6A 1UBXA 3AQBB 3WEIA 5ILKA 3KROB 3LGKA 5B0KA 1YYSA 2F94F 3WJKA 1YHMA 3IPIA 2Z7IA 4DWBA 4N1ZF 4QXSF 4K10A 3OABB 4Q23A 5IK0A 2RAHA 3P8RA 3KB9A 3WEKA 1RTRA 2PS5A 3AQCB 1VG3A 3LK5A 4DWGA 2E8WA 5AELA 3LJIA 3AE0A 3KRPA 4N9UA 2PS7A 2QISA 4KK2A 5ILZA 4H5CF 5A0KA 4PVYF 2AEKA 5E8KA 4HD1A 3TS7A 1WY0A 3ICKA 2J1OA 3M9UA 5A0IA 5DW7A 3LDWA 4LA5A 1HXAA 3LSNA 2F89F 2PS4A 5EROA 4JZBA 4GP1A 5JA0F 1N1BA 3N0FA 2F7MF 5H9DA 4F6XA 4OMHA 4LUUA 2E93A 1ZW5A 4KPJA 3KRAB 3RYEA 3WCFA 5IMNA 3KRAA 3ZL6A 1HXGA 4GP2A 3WCCA 2OPMA 1KIYA 3LLWA 4NFIF 3V1XA 1JFAA 2OGDA 5B03A 3WCIA 5HNAA 4E9UA 1YYQA 2ZEUA 4KVDA 3LG5A 5DIQF 5ILYA 3WCBA 4RNQA 3EZ3A 2ZCRA 3TFVA 2F8CF 2OPNA 4LZ0A 2E94A 5EAUA 3M0GA 1YHKA 3V66A 4EA2A 2E8XA 3ZMCA 3G4FA 4LFVF 3TFPA 2Q80A 4MC8A 2Z7HA 3Q1OA 4LIXA 1JFGA 3TC1A 5A0JA 3CP6A 1WL3A 4OMGA 3LGZB 5HN9A 5JV2F 3ADZA 3NF2A 3SDUA 3WE9A 4NG6A 1YYTA 4DEMF 3DYGA 3EFQA 2AZKA 2Z52A 4F62A 5DZ2A 3WC9A 2E90A 4NFJF 4MC0A 2Z4ZA 2Z4XA 3BNYA 3LEEA 5IKHA 1WL0A 4XQSF 5HN8A 5B00A 2J5CA 4NKFA 4P0XA 3UCAA 4P0VA 1WKZA 4RXEA 2Q9YA 3LMDA 3V1VA 1N21A 4LFGA 3SAEA 3ZOUA 4OGUA 1HM7A 2ZCOA 4LPHF 3N49F 5KSXF 5DJPF 5ILIA 5DGNF 4KQSA 1EZFA 4LA6A 3VJEA 3N3DA 4NUAA 2Q58A 2F92F 3G4DA 3P5PA 2PS6A 3ACXA 3KRPB 5ILHA 5AFXA 5DGMF 4JVJF 4XQRF 3N1VF 4LZ3A 2AELA 3ZMBA 2Z50A 3KBKA 3MAVA 4NKEA 4KQ5A 3WSBA 4E9ZA 4QPFA 2ZCSA 5C05A 5IK9A 4KFAA 3M00A 1YV5A 4E1EA 5JUZF 4KPDA 1UBWA 1FPSA 1RQIA 2F9KF 1YYRA 4RXAA 4LZCA 5IL8A 2AZLA 4DXJA 3LOMA 3Q2ZA 1WL1A 4XQTF 3BNXA 1DGPA 5JV1F 4KVWA 4P0WA 3WCJA 5ER8A 3EGTA 3CKEA 5B0MA 5IM1A 4JXYA 4LPGF 3WJOA 2OA6A 5CG6A 3ICZA 3N3LF 3QQVA 3PH7A 3P5RA 1V4HA 2E92A 4KVIA 4NFKF 5IMPA 1KIZA 4JYXA 4LTVA 3ACWA 3NPRA 5ERNA 3WJNA 4LLTA 3PDEA 5ILJA 4L2XF 2E95A 3VJ9A 5IL3A 3CC9A 4JZXA 2PS8A 3RYWA 3WEJA 2DH4A 1V4EA 1V4JA 2FTZA 4F6VA 3WEGA 3SDQA 1HM4A 2AETA 3Q2QA 3SDVA 2E8VA 2J1PA 3RMGA 2E8UA 5CG5A 1YJ4A 3N1WF 3DYFA 4JXNA 3M02A 4LFEA 1VG4A 3ACYA 4RYPA 3PYAA 4PVXF 5B0IA 3N6KF 5DGSF 4H5DF 1DI1A 3P41A 1VG7A 3WSAA 3ZCDA 2Z4VA 1WMWA 3DYHA 4GA3A 5B0LA 4LTZA 5I1UA 2Z4YA 3MZVA 3AQ0A 4LOBA 4RXCA 3VJBA 1N20A 3PYBA 4MC3A 5IN8A 4EA0A 3KRCB 3NPKA 3KRCA 2ZCQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OKM A;  2FOR A;  3KRO A;  5ILD A;  3VJD A;  5DJR F;  2EWG A;  4H5E F;  1HX9 A;  3LVS A;  2P1C A;  3OAB A;  5DHI A;  4DI5 A;  2AZJ A;  2I19 A;  5E8H A;  1N23 A;  4GAX A;  2E8T A;  3N5J F;  3WCE A;  4LLS A;  2Q9Z A;  3OAC B;  5IVG A;  4WK5 A;  3OAC A;  1N24 A;  3SDR A;  5EAS A;  3TFN A;  3N5H F;  3WCM A;  1UBY A;  3M01 A;  3QKC A;  1UBV A;  3WCA A;  1YQ7 A;  3NRI A;  3ICN A;  2ONH A;  5B01 A;  5IKA A;  4FJQ A;  3WEF A;  3VJC A;  3Q30 A;  5AYP A;  2H8O A;  3W7F A;  3WEH A;  3PKO A;  5IMI A;  2Z78 A;  3N46 F;  2O1O A;  3N0G A;  5JV0 F;  4KKM A;  3ASX A;  4KVY A;  2Z4W A;  2ZY1 A;  5ERM A;  5AHU B;  5B02 A;  1VG6 A;  1V4K A;  2E91 A;  4RXD A;  4OKZ A;  5B0J A;  1V4I A;  3S9V A;  2E4O A;  1N1Z A;  3ICM A;  3APZ A;  1HXC A;  3ID0 A;  3OYR A;  2ZEV A;  1WL2 A;  4UMJ A;  4KWD A;  4DHD A;  4KUX A;  5DHK A;  5EAT A;  1PS1 A;  1RQJ A;  5HN7 A;  4ZQ8 A;  4LXW A;  3KRF B;  3KRF A;  1YYU A;  4KQU A;  3WCL A;  3IBA A;  3WCD A;  3WCG A;  4FP4 A;  3B7L A;  5IK6 A;  3RBM A;  5DJV F;  3N45 F;  3LZ9 A;  3S4J A;  1YHL A;  1N22 A;  2ONG A;  2F8Z F;  5E8L A;  3VJA A;  3P8L A;  3WCH A;  4EA1 A;  4DZW A;  1VG2 A;  3VJ8 A;  3SDT A;  2VF6 A;  1UBX A;  3AQB B;  3WEI A;  5ILK A;  3KRO B;  3LGK A;  5B0K A;  1YYS A;  2F94 F;  3WJK A;  1YHM A;  3IPI A;  2Z7I A;  4DWB A;  4N1Z F;  4QXS F;  4K10 A;  3OAB B;  4Q23 A;  5IK0 A;  2RAH A;  3P8R A;  3KB9 A;  3WEK A;  1RTR A;  2PS5 A;  3AQC B;  1VG3 A;  3LK5 A;  4DWG A;  2E8W A;  5AEL A;  3LJI A;  3AE0 A;  3KRP A;  4N9U A;  2PS7 A;  2QIS A;  4KK2 A;  5ILZ A;  4H5C F;  5A0K A;  4PVY F;  2AEK A;  5E8K A;  4HD1 A;  3TS7 A;  1WY0 A;  3ICK A;  2J1O A;  3M9U A;  5A0I A;  5DW7 A;  3LDW A;  4LA5 A;  1HXA A;  3LSN A;  2F89 F;  2PS4 A;  5ERO A;  4JZB A;  4GP1 A;  5JA0 F;  1N1B A;  3N0F A;  2F7M F;  5H9D A;  4F6X A;  4OMH A;  4LUU A;  2E93 A;  1ZW5 A;  4KPJ A;  3KRA B;  3RYE A;  3WCF A;  5IMN A;  3KRA A;  3ZL6 A;  1HXG A;  4GP2 A;  3WCC A;  2OPM A;  1KIY A;  3LLW A;  4NFI F;  3V1X A;  1JFA A;  2OGD A;  5B03 A;  3WCI A;  5HNA A;  4E9U A;  1YYQ A;  2ZEU A;  4KVD A;  3LG5 A;  5DIQ F;  5ILY A;  3WCB A;  4RNQ A;  3EZ3 A;  2ZCR A;  3TFV A;  2F8C F;  2OPN A;  4LZ0 A;  2E94 A;  5EAU A;  3M0G A;  1YHK A;  3V66 A;  4EA2 A;  2E8X A;  3ZMC A;  3G4F A;  4LFV F;  3TFP A;  2Q80 A;  4MC8 A;  2Z7H A;  3Q1O A;  4LIX A;  1JFG A;  3TC1 A;  5A0J A;  3CP6 A;  1WL3 A;  4OMG A;  3LGZ B;  5HN9 A;  5JV2 F;  3ADZ A;  3NF2 A;  3SDU A;  3WE9 A;  4NG6 A;  1YYT A;  4DEM F;  3DYG A;  3EFQ A;  2AZK A;  2Z52 A;  4F62 A;  5DZ2 A;  3WC9 A;  2E90 A;  4NFJ F;  4MC0 A;  2Z4Z A;  2Z4X A;  3BNY A;  3LEE A;  5IKH A;  1WL0 A;  4XQS F;  5HN8 A;  5B00 A;  2J5C A;  4NKF A;  4P0X A;  3UCA A;  4P0V A;  1WKZ A;  4RXE A;  2Q9Y A;  3LMD A;  3V1V A;  1N21 A;  4LFG A;  3SAE A;  3ZOU A;  4OGU A;  1HM7 A;  2ZCO A;  4LPH F;  3N49 F;  5KSX F;  5DJP F;  5ILI A;  5DGN F;  4KQS A;  1EZF A;  4LA6 A;  3VJE A;  3N3D A;  4NUA A;  2Q58 A;  2F92 F;  3G4D A;  3P5P A;  2PS6 A;  3ACX A;  3KRP B;  5ILH A;  5AFX A;  5DGM F;  4JVJ F;  4XQR F;  3N1V F;  4LZ3 A;  2AEL A;  3ZMB A;  2Z50 A;  3KBK A;  3MAV A;  4NKE A;  4KQ5 A;  3WSB A;  4E9Z A;  4QPF A;  2ZCS A;  5C05 A;  5IK9 A;  4KFA A;  3M00 A;  1YV5 A;  4E1E A;  5JUZ F;  4KPD A;  1UBW A;  1FPS A;  1RQI A;  2F9K F;  1YYR A;  4RXA A;  4LZC A;  5IL8 A;  2AZL A;  4DXJ A;  3LOM A;  3Q2Z A;  1WL1 A;  4XQT F;  3BNX A;  1DGP A;  5JV1 F;  4KVW A;  4P0W A;  3WCJ A;  5ER8 A;  3EGT A;  3CKE A;  5B0M A;  5IM1 A;  4JXY A;  4LPG F;  3WJO A;  2OA6 A;  5CG6 A;  3ICZ A;  3N3L F;  3QQV A;  3PH7 A;  3P5R A;  1V4H A;  2E92 A;  4KVI A;  4NFK F;  5IMP A;  1KIZ A;  4JYX A;  4LTV A;  3ACW A;  3NPR A;  5ERN A;  3WJN A;  4LLT A;  3PDE A;  5ILJ A;  4L2X F;  2E95 A;  3VJ9 A;  5IL3 A;  3CC9 A;  4JZX A;  2PS8 A;  3RYW A;  3WEJ A;  2DH4 A;  1V4E A;  1V4J A;  2FTZ A;  4F6V A;  3WEG A;  3SDQ A;  1HM4 A;  2AET A;  3Q2Q A;  3SDV A;  2E8V A;  2J1P A;  3RMG A;  2E8U A;  5CG5 A;  1YJ4 A;  3N1W F;  3DYF A;  4JXN A;  3M02 A;  4LFE A;  1VG4 A;  3ACY A;  4RYP A;  3PYA A;  4PVX F;  5B0I A;  3N6K F;  5DGS F;  4H5D F;  1DI1 A;  3P41 A;  1VG7 A;  3WSA A;  3ZCD A;  2Z4V A;  1WMW A;  3DYH A;  4GA3 A;  5B0L A;  4LTZ A;  5I1U A;  2Z4Y A;  3MZV A;  3AQ0 A;  4LOB A;  4RXC A;  3VJB A;  1N20 A;  3PYB A;  4MC3 A;  5IN8 A;  4EA0 A;  3KRC B;  3NPK A;  3KRC A;  2ZCQ A; 
#chains in the Genus database with same CATH topology
 4OKM A;  2FOR A;  3KRO A;  5ILD A;  3VJD A;  5DJR F;  2EWG A;  4H5E F;  1HX9 A;  3LVS A;  2P1C A;  3OAB A;  5DHI A;  4DI5 A;  2AZJ A;  2I19 A;  5E8H A;  1N23 A;  4GAX A;  2E8T A;  3N5J F;  3WCE A;  4LLS A;  2Q9Z A;  3OAC B;  5IVG A;  4WK5 A;  3OAC A;  1N24 A;  3SDR A;  5EAS A;  3TFN A;  3N5H F;  3WCM A;  1UBY A;  3M01 A;  3QKC A;  1UBV A;  3WCA A;  1YQ7 A;  3NRI A;  3ICN A;  2ONH A;  5B01 A;  5IKA A;  4FJQ A;  3WEF A;  3VJC A;  3Q30 A;  5AYP A;  2H8O A;  3W7F A;  3WEH A;  3PKO A;  5IMI A;  2Z78 A;  3N46 F;  2O1O A;  3N0G A;  5JV0 F;  4KKM A;  3ASX A;  4KVY A;  2Z4W A;  2ZY1 A;  5ERM A;  5AHU B;  5B02 A;  1VG6 A;  1V4K A;  2E91 A;  4RXD A;  4OKZ A;  5B0J A;  1V4I A;  3S9V A;  2E4O A;  1N1Z A;  3ICM A;  3APZ A;  1HXC A;  3ID0 A;  3OYR A;  2ZEV A;  1WL2 A;  4UMJ A;  4KWD A;  4DHD A;  4KUX A;  5DHK A;  5EAT A;  1PS1 A;  1RQJ A;  5HN7 A;  4ZQ8 A;  4LXW A;  3KRF B;  3KRF A;  1YYU A;  4KQU A;  3WCL A;  3IBA A;  3WCD A;  3WCG A;  4FP4 A;  3B7L A;  5IK6 A;  3RBM A;  5DJV F;  3N45 F;  3LZ9 A;  3S4J A;  1YHL A;  1N22 A;  2ONG A;  2F8Z F;  5E8L A;  3VJA A;  3P8L A;  3WCH A;  4EA1 A;  4DZW A;  1VG2 A;  3VJ8 A;  3SDT A;  2VF6 A;  1UBX A;  3AQB B;  3WEI A;  5ILK A;  3KRO B;  3LGK A;  5B0K A;  1YYS A;  2F94 F;  3WJK A;  1YHM A;  3IPI A;  2Z7I A;  4DWB A;  4N1Z F;  4QXS F;  4K10 A;  3OAB B;  4Q23 A;  5IK0 A;  2RAH A;  3P8R A;  3KB9 A;  3WEK A;  1RTR A;  2PS5 A;  3AQC B;  1VG3 A;  3LK5 A;  4DWG A;  2E8W A;  5AEL A;  3LJI A;  3AE0 A;  3KRP A;  4N9U A;  2PS7 A;  2QIS A;  4KK2 A;  5ILZ A;  4H5C F;  5A0K A;  4PVY F;  2AEK A;  5E8K A;  4HD1 A;  3TS7 A;  1WY0 A;  3ICK A;  2J1O A;  3M9U A;  5A0I A;  5DW7 A;  3LDW A;  4LA5 A;  1HXA A;  3LSN A;  2F89 F;  2PS4 A;  5ERO A;  4JZB A;  4GP1 A;  5JA0 F;  1N1B A;  3N0F A;  2F7M F;  5H9D A;  4F6X A;  4OMH A;  4LUU A;  2E93 A;  1ZW5 A;  4KPJ A;  3KRA B;  3RYE A;  3WCF A;  5IMN A;  3KRA A;  3ZL6 A;  1HXG A;  4GP2 A;  3WCC A;  2OPM A;  1KIY A;  3LLW A;  4NFI F;  3V1X A;  1JFA A;  2OGD A;  5B03 A;  3WCI A;  5HNA A;  4E9U A;  1YYQ A;  2ZEU A;  4KVD A;  3LG5 A;  5DIQ F;  5ILY A;  3WCB A;  4RNQ A;  3EZ3 A;  2ZCR A;  3TFV A;  2F8C F;  2OPN A;  4LZ0 A;  2E94 A;  5EAU A;  3M0G A;  1YHK A;  3V66 A;  4EA2 A;  2E8X A;  3ZMC A;  3G4F A;  4LFV F;  3TFP A;  2Q80 A;  4MC8 A;  2Z7H A;  3Q1O A;  4LIX A;  1JFG A;  3TC1 A;  5A0J A;  3CP6 A;  1WL3 A;  4OMG A;  3LGZ B;  5HN9 A;  5JV2 F;  3ADZ A;  3NF2 A;  3SDU A;  3WE9 A;  4NG6 A;  1YYT A;  4DEM F;  3DYG A;  3EFQ A;  2AZK A;  2Z52 A;  4F62 A;  5DZ2 A;  3WC9 A;  2E90 A;  4NFJ F;  4MC0 A;  2Z4Z A;  2Z4X A;  3BNY A;  3LEE A;  5IKH A;  1WL0 A;  4XQS F;  5HN8 A;  5B00 A;  2J5C A;  4NKF A;  4P0X A;  3UCA A;  4P0V A;  1WKZ A;  4RXE A;  2Q9Y A;  3LMD A;  3V1V A;  1N21 A;  4LFG A;  3SAE A;  3ZOU A;  4OGU A;  1HM7 A;  2ZCO A;  4LPH F;  3N49 F;  5KSX F;  5DJP F;  5ILI A;  5DGN F;  4KQS A;  1EZF A;  4LA6 A;  3VJE A;  3N3D A;  4NUA A;  2Q58 A;  2F92 F;  3G4D A;  3P5P A;  2PS6 A;  3ACX A;  3KRP B;  5ILH A;  5AFX A;  5DGM F;  4JVJ F;  4XQR F;  3N1V F;  4LZ3 A;  2AEL A;  3ZMB A;  2Z50 A;  3KBK A;  3MAV A;  4NKE A;  4KQ5 A;  3WSB A;  4E9Z A;  4QPF A;  2ZCS A;  5C05 A;  5IK9 A;  4KFA A;  3M00 A;  1YV5 A;  4E1E A;  5JUZ F;  4KPD A;  1UBW A;  1FPS A;  1RQI A;  2F9K F;  1YYR A;  4RXA A;  4LZC A;  5IL8 A;  2AZL A;  4DXJ A;  3LOM A;  3Q2Z A;  1WL1 A;  4XQT F;  3BNX A;  1DGP A;  5JV1 F;  4KVW A;  4P0W A;  3WCJ A;  5ER8 A;  3EGT A;  3CKE A;  5B0M A;  5IM1 A;  4JXY A;  4LPG F;  3WJO A;  2OA6 A;  5CG6 A;  3ICZ A;  3N3L F;  3QQV A;  3PH7 A;  3P5R A;  1V4H A;  2E92 A;  4KVI A;  4NFK F;  5IMP A;  1KIZ A;  4JYX A;  4LTV A;  3ACW A;  3NPR A;  5ERN A;  3WJN A;  4LLT A;  3PDE A;  5ILJ A;  4L2X F;  2E95 A;  3VJ9 A;  5IL3 A;  3CC9 A;  4JZX A;  2PS8 A;  3RYW A;  3WEJ A;  2DH4 A;  1V4E A;  1V4J A;  2FTZ A;  4F6V A;  3WEG A;  3SDQ A;  1HM4 A;  2AET A;  3Q2Q A;  3SDV A;  2E8V A;  2J1P A;  3RMG A;  2E8U A;  5CG5 A;  1YJ4 A;  3N1W F;  3DYF A;  4JXN A;  3M02 A;  4LFE A;  1VG4 A;  3ACY A;  4RYP A;  3PYA A;  4PVX F;  5B0I A;  3N6K F;  5DGS F;  4H5D F;  1DI1 A;  3P41 A;  1VG7 A;  3WSA A;  3ZCD A;  2Z4V A;  1WMW A;  3DYH A;  4GA3 A;  5B0L A;  4LTZ A;  5I1U A;  2Z4Y A;  3MZV A;  3AQ0 A;  4LOB A;  4RXC A;  3VJB A;  1N20 A;  3PYB A;  4MC3 A;  5IN8 A;  4EA0 A;  3KRC B;  3NPK A;  3KRC A;  2ZCQ A; 
#chains in the Genus database with same CATH homology
 4OKM A;  2FOR A;  3KRO A;  5ILD A;  3VJD A;  5DJR F;  2EWG A;  4H5E F;  1HX9 A;  3LVS A;  2P1C A;  3OAB A;  5DHI A;  4DI5 A;  2AZJ A;  2I19 A;  5E8H A;  1N23 A;  4GAX A;  2E8T A;  3N5J F;  3WCE A;  4LLS A;  2Q9Z A;  3OAC B;  5IVG A;  4WK5 A;  3OAC A;  1N24 A;  3SDR A;  5EAS A;  3TFN A;  3N5H F;  3WCM A;  1UBY A;  3M01 A;  3QKC A;  1UBV A;  3WCA A;  1YQ7 A;  3NRI A;  3ICN A;  2ONH A;  5B01 A;  5IKA A;  4FJQ A;  3WEF A;  3VJC A;  3Q30 A;  5AYP A;  2H8O A;  3W7F A;  3WEH A;  3PKO A;  5IMI A;  2Z78 A;  3N46 F;  2O1O A;  3N0G A;  5JV0 F;  4KKM A;  3ASX A;  4KVY A;  2Z4W A;  2ZY1 A;  5ERM A;  5AHU B;  5B02 A;  1VG6 A;  1V4K A;  2E91 A;  4RXD A;  4OKZ A;  5B0J A;  1V4I A;  3S9V A;  2E4O A;  1N1Z A;  3ICM A;  3APZ A;  1HXC A;  3ID0 A;  3OYR A;  2ZEV A;  1WL2 A;  4UMJ A;  4KWD A;  4DHD A;  4KUX A;  5DHK A;  5EAT A;  1PS1 A;  1RQJ A;  5HN7 A;  4ZQ8 A;  4LXW A;  3KRF B;  3KRF A;  1YYU A;  4KQU A;  3WCL A;  3IBA A;  3WCD A;  3WCG A;  4FP4 A;  3B7L A;  5IK6 A;  3RBM A;  5DJV F;  3N45 F;  3LZ9 A;  3S4J A;  1YHL A;  1N22 A;  2ONG A;  2F8Z F;  5E8L A;  3VJA A;  3P8L A;  3WCH A;  4EA1 A;  4DZW A;  1VG2 A;  3VJ8 A;  3SDT A;  2VF6 A;  1UBX A;  3AQB B;  3WEI A;  5ILK A;  3KRO B;  3LGK A;  5B0K A;  1YYS A;  2F94 F;  3WJK A;  1YHM A;  3IPI A;  2Z7I A;  4DWB A;  4N1Z F;  4QXS F;  4K10 A;  3OAB B;  4Q23 A;  5IK0 A;  2RAH A;  3P8R A;  3KB9 A;  3WEK A;  1RTR A;  2PS5 A;  3AQC B;  1VG3 A;  3LK5 A;  4DWG A;  2E8W A;  5AEL A;  3LJI A;  3AE0 A;  3KRP A;  4N9U A;  2PS7 A;  2QIS A;  4KK2 A;  5ILZ A;  4H5C F;  5A0K A;  4PVY F;  2AEK A;  5E8K A;  4HD1 A;  3TS7 A;  1WY0 A;  3ICK A;  2J1O A;  3M9U A;  5A0I A;  5DW7 A;  3LDW A;  4LA5 A;  1HXA A;  3LSN A;  2F89 F;  2PS4 A;  5ERO A;  4JZB A;  4GP1 A;  5JA0 F;  1N1B A;  3N0F A;  2F7M F;  5H9D A;  4F6X A;  4OMH A;  4LUU A;  2E93 A;  1ZW5 A;  4KPJ A;  3KRA B;  3RYE A;  3WCF A;  5IMN A;  3KRA A;  3ZL6 A;  1HXG A;  4GP2 A;  3WCC A;  2OPM A;  1KIY A;  3LLW A;  4NFI F;  3V1X A;  1JFA A;  2OGD A;  5B03 A;  3WCI A;  5HNA A;  4E9U A;  1YYQ A;  2ZEU A;  4KVD A;  3LG5 A;  5DIQ F;  5ILY A;  3WCB A;  4RNQ A;  3EZ3 A;  2ZCR A;  3TFV A;  2F8C F;  2OPN A;  4LZ0 A;  2E94 A;  5EAU A;  3M0G A;  1YHK A;  3V66 A;  4EA2 A;  2E8X A;  3ZMC A;  3G4F A;  4LFV F;  3TFP A;  2Q80 A;  4MC8 A;  2Z7H A;  3Q1O A;  4LIX A;  1JFG A;  3TC1 A;  5A0J A;  3CP6 A;  1WL3 A;  4OMG A;  3LGZ B;  5HN9 A;  5JV2 F;  3ADZ A;  3NF2 A;  3SDU A;  3WE9 A;  4NG6 A;  1YYT A;  4DEM F;  3DYG A;  3EFQ A;  2AZK A;  2Z52 A;  4F62 A;  5DZ2 A;  3WC9 A;  2E90 A;  4NFJ F;  4MC0 A;  2Z4Z A;  2Z4X A;  3BNY A;  3LEE A;  5IKH A;  1WL0 A;  4XQS F;  5HN8 A;  5B00 A;  2J5C A;  4NKF A;  4P0X A;  3UCA A;  4P0V A;  1WKZ A;  4RXE A;  2Q9Y A;  3LMD A;  3V1V A;  1N21 A;  4LFG A;  3SAE A;  3ZOU A;  4OGU A;  1HM7 A;  2ZCO A;  4LPH F;  3N49 F;  5KSX F;  5DJP F;  5ILI A;  5DGN F;  4KQS A;  1EZF A;  4LA6 A;  3VJE A;  3N3D A;  4NUA A;  2Q58 A;  2F92 F;  3G4D A;  3P5P A;  2PS6 A;  3ACX A;  3KRP B;  5ILH A;  5AFX A;  5DGM F;  4JVJ F;  4XQR F;  3N1V F;  4LZ3 A;  2AEL A;  3ZMB A;  2Z50 A;  3KBK A;  3MAV A;  4NKE A;  4KQ5 A;  3WSB A;  4E9Z A;  4QPF A;  2ZCS A;  5C05 A;  5IK9 A;  4KFA A;  3M00 A;  1YV5 A;  4E1E A;  5JUZ F;  4KPD A;  1UBW A;  1FPS A;  1RQI A;  2F9K F;  1YYR A;  4RXA A;  4LZC A;  5IL8 A;  2AZL A;  4DXJ A;  3LOM A;  3Q2Z A;  1WL1 A;  4XQT F;  3BNX A;  1DGP A;  5JV1 F;  4KVW A;  4P0W A;  3WCJ A;  5ER8 A;  3EGT A;  3CKE A;  5B0M A;  5IM1 A;  4JXY A;  4LPG F;  3WJO A;  2OA6 A;  5CG6 A;  3ICZ A;  3N3L F;  3QQV A;  3PH7 A;  3P5R A;  1V4H A;  2E92 A;  4KVI A;  4NFK F;  5IMP A;  1KIZ A;  4JYX A;  4LTV A;  3ACW A;  3NPR A;  5ERN A;  3WJN A;  4LLT A;  3PDE A;  5ILJ A;  4L2X F;  2E95 A;  3VJ9 A;  5IL3 A;  3CC9 A;  4JZX A;  2PS8 A;  3RYW A;  3WEJ A;  2DH4 A;  1V4E A;  1V4J A;  2FTZ A;  4F6V A;  3WEG A;  3SDQ A;  1HM4 A;  2AET A;  3Q2Q A;  3SDV A;  2E8V A;  2J1P A;  3RMG A;  2E8U A;  5CG5 A;  1YJ4 A;  3N1W F;  3DYF A;  4JXN A;  3M02 A;  4LFE A;  1VG4 A;  3ACY A;  4RYP A;  3PYA A;  4PVX F;  5B0I A;  3N6K F;  5DGS F;  4H5D F;  1DI1 A;  3P41 A;  1VG7 A;  3WSA A;  3ZCD A;  2Z4V A;  1WMW A;  3DYH A;  4GA3 A;  5B0L A;  4LTZ A;  5I1U A;  2Z4Y A;  3MZV A;  3AQ0 A;  4LOB A;  4RXC A;  3VJB A;  1N20 A;  3PYB A;  4MC3 A;  5IN8 A;  4EA0 A;  3KRC B;  3NPK A;  3KRC A;  2ZCQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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