2Z78A

S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-806
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
337
structure length
321
Chain Sequence
NKMEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNLKDFQMSKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPELLYIIDHLSEL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Saccharomyces cerevisiae
molecule keywords Geranylgeranyl pyrophosphate synthetase
total genus 138
structure length 321
sequence length 337
chains with identical sequence B
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2007-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 2z78A00
5E8HA 5ERNA 3KRPA 4OKMA 5IMNA 3AQBB 1JFAA 3EZ3A 3PYBA 2Z78A 3MZVA 2E8WA 3EFQA 4KVWA 4E9UA 4JXNA 1YYUA 4DWGA 4LLTA 4RXEA 2E8XA 5IL3A 2F8ZF 1N20A 2PS7A 1V4EA 3LJIA 1UBVA 1RQJA 4KKMA 3APZA 3OYRA 5B0MA 3WCEA 5DGNF 2AZJA 2PS4A 4FJQA 1KIYA 3LGZB 2ZEVA 5DW7A 5IK0A 1VG3A 3MAVA 2RAHA 3NPRA 5B03A 3ACYA 5IK6A 3WCDA 4DWBA 4KQ5A 1N1ZA 1YHLA 2Z4XA 5H9DA 4LA6A 5AFXA 3EGTA 4XQSF 4PVYF 4RXCA 3KRFB 2J1OA 5DJVF 1HXCA 4NFJF 1HXAA 3ICZA 5DJPF 4OMGA 1N22A 3WSBA 3KRPB 4KVDA 5IVGA 2Z7HA 2QISA 5B0KA 3RBMA 3S9VA 3WCLA 5ILDA 2Z4ZA 3LDWA 5JV0F 3B7LA 3CKEA 3LSNA 5JV2F 1YYTA 3ICMA 4RXAA 3ID0A 1YQ7A 5AHUB 3SDRA 2ZCSA 4F6VA 2EWGA 3RYWA 1RTRA 3VJEA 4RXDA 4KPDA 4KPJA 3Q2QA 5B0LA 1UBXA 1N21A 4NFKF 4KVYA 4MC8A 3VJ8A 2F92F 2OGDA 2OA6A 5B01A 3M0GA 4LPHF 3N5JF 5CG5A 4QXSF 3WEIA 1RQIA 4EA0A 2E91A 4NFIF 2AELA 3VJBA 3Q1OA 5A0IA 1PS1A 2E93A 5DGSF 3ZMBA 5EROA 3WCJA 3LG5A 3N1VF 5B0JA 3LOMA 4GP1A 3M9UA 5IK9A 2Z7IA 3KRFA 3BNXA 1VG7A 2OPNA 5ILZA 4HD1A 3W7FA 4EA1A 1YYRA 4H5DF 4GA3A 4F6XA 3V1VA 3TS7A 2VF6A 3WCGA 5IN8A 4KQSA 4OMHA 3N46F 4P0WA 3WCHA 5IL8A 4MC3A 2F89F 1YYQA 1EZFA 3N3DA 3N0GA 4DXJA 4F62A 1YHMA 1YHKA 3IPIA 5DIQF 4LLSA 3ICKA 5ILYA 4DEMF 3KBKA 3PDEA 2J1PA 3Q2ZA 3M00A 3WEKA 2Q9ZA 4K10A 3N5HF 3WCCA 5JA0F 4KUXA 3G4FA 2ZY1A 3KROA 3P41A 3LK5A 2Z4WA 3WCMA 3S4JA 3RMGA 4WK5A 5IM1A 3SDTA 5HNAA 2E90A 4LPGF 4LUUA 5JUZF 3WCIA 3NPKA 1DGPA 5DJRF 3WEJA 1WL3A 4H5EF 3DYGA 5DZ2A 3N3LF 2ZCRA 2Z50A 3V1XA 2ONGA 4UMJA 3KRAA 5AELA 5ERMA 3TFNA 2F94F 4LFGA 5E8LA 3CP6A 5DHKA 1VG2A 2H8OA 2E8UA 4XQTF 4P0XA 3KB9A 5EAUA 4E1EA 1YJ4A 3TFPA 3KROB 3DYFA 1HM4A 2ZCOA 3N0FA 3SDUA 1WY0A 1HM7A 1WL0A 3QKCA 1DI1A 2Q9YA 3WCFA 1V4IA 4OKZA 4KK2A 1KIZA 4KFAA 4LFVF 1JFGA 3AQCB 3PKOA 3LGKA 3LZ9A 3OACA 3KRAB 4RYPA 3WEFA 5HN7A 3WE9A 3V66A 2DH4A 4LOBA 4PVXF 4DI5A 5A0KA 4KQUA 3WJNA 4NUAA 5IMPA 4NKFA 3CC9A 4RNQA 5B00A 3QQVA 2ZEUA 5ILHA 3NRIA 5DGMF 2F9KF 5IKAA 2PS6A 2PS8A 3P8LA 4NKEA 2F7MF 3M01A 3LEEA 4KVIA 3RYEA 2E4OA 4JZBA 3LLWA 3LVSA 4FP4A 5JV1F 3TFVA 3N6KF 4JYXA 2Q80A 3N45F 2FORA 3OACB 1V4HA 3G4DA 3AQ0A 3ZOUA 1V4KA 4E9ZA 3SAEA 3VJDA 3P8RA 4MC0A 5EASA 3P5RA 3TC1A 5HN9A 3OABB 3IBAA 2OPMA 2ZCQA 5A0JA 2J5CA 3BNYA 3KRCB 3Q30A 5B02A 1WL1A 4LXWA 2E8TA 4JZXA 3WJKA 4KWDA 5EATA 2E94A 3ZCDA 5I1UA 2PS5A 2FTZA 3P5PA 1ZW5A 4LFEA 1WKZA 4P0VA 4ZQ8A 4OGUA 5B0IA 5C05A 1HXGA 4DZWA 3VJ9A 4Q23A 3WEHA 1VG6A 4EA2A 2Z4YA 5IMIA 1N1BA 2Z52A 4DHDA 5ILIA 1WMWA 2O1OA 5DHIA 1FPSA 4GP2A 3ICNA 4JVJF 1N23A 4GAXA 3WCBA 2E92A 2AZLA 4N1ZF 4XQRF 3ADZA 4LA5A 5CG6A 2AZKA 3M02A 1UBYA 3UCAA 5AYPA 3ZMCA 1YV5A 1N24A 5HN8A 3PH7A 4LTVA 2AEKA 3ACXA 3WCAA 1YYSA 2Q58A 4N9UA 2Z4VA 5KSXF 3WC9A 3VJAA 4LZ0A 1V4JA 2E95A 1VG4A 4L2XF 2E8VA 3WEGA 1UBWA 3N49F 4H5CF 5ER8A 4LZCA 3SDVA 5IKHA 3ACWA 3PYAA 5ILKA 4QPFA 2I19A 3SDQA 4JXYA 3N1WF 3VJCA 3OABA 2F8CF 3ZL6A 3NF2A 5E8KA 3WSAA 4LIXA 3LMDA 3ASXA 1HX9A 3DYHA 3KRCA 4LTZA 2AETA 2ONHA 3AE0A 4LZ3A 2P1CA 4NG6A 1WL2A 5ILJA 3WJOA
chains in the Genus database with same CATH superfamily
5E8HA 5ERNA 3KRPA 4OKMA 5IMNA 3AQBB 1JFAA 3EZ3A 3PYBA 2Z78A 3MZVA 2E8WA 3EFQA 4KVWA 4E9UA 4JXNA 1YYUA 4DWGA 4LLTA 4RXEA 2E8XA 5IL3A 2F8ZF 1N20A 2PS7A 1V4EA 3LJIA 1UBVA 1RQJA 4KKMA 3APZA 3OYRA 5B0MA 3WCEA 5DGNF 2AZJA 2PS4A 4FJQA 1KIYA 3LGZB 2ZEVA 5DW7A 5IK0A 1VG3A 3MAVA 2RAHA 3NPRA 5B03A 3ACYA 5IK6A 3WCDA 4DWBA 4KQ5A 1N1ZA 1YHLA 2Z4XA 5H9DA 4LA6A 5AFXA 3EGTA 4XQSF 4PVYF 4RXCA 3KRFB 2J1OA 5DJVF 1HXCA 4NFJF 1HXAA 3ICZA 5DJPF 4OMGA 1N22A 3WSBA 3KRPB 4KVDA 5IVGA 2Z7HA 2QISA 5B0KA 3RBMA 3S9VA 3WCLA 5ILDA 2Z4ZA 3LDWA 5JV0F 3B7LA 3CKEA 3LSNA 5JV2F 1YYTA 3ICMA 4RXAA 3ID0A 1YQ7A 5AHUB 3SDRA 2ZCSA 4F6VA 2EWGA 3RYWA 1RTRA 3VJEA 4RXDA 4KPDA 4KPJA 3Q2QA 5B0LA 1UBXA 1N21A 4NFKF 4KVYA 4MC8A 3VJ8A 2F92F 2OGDA 2OA6A 5B01A 3M0GA 4LPHF 3N5JF 5CG5A 4QXSF 3WEIA 1RQIA 4EA0A 2E91A 4NFIF 2AELA 3VJBA 3Q1OA 5A0IA 1PS1A 2E93A 5DGSF 3ZMBA 5EROA 3WCJA 3LG5A 3N1VF 5B0JA 3LOMA 4GP1A 3M9UA 5IK9A 2Z7IA 3KRFA 3BNXA 1VG7A 2OPNA 5ILZA 4HD1A 3W7FA 4EA1A 1YYRA 4H5DF 4GA3A 4F6XA 3V1VA 3TS7A 2VF6A 3WCGA 5IN8A 4KQSA 4OMHA 3N46F 4P0WA 3WCHA 5IL8A 4MC3A 2F89F 1YYQA 1EZFA 3N3DA 3N0GA 4DXJA 4F62A 1YHMA 1YHKA 3IPIA 5DIQF 4LLSA 3ICKA 5ILYA 4DEMF 3KBKA 3PDEA 2J1PA 3Q2ZA 3M00A 3WEKA 2Q9ZA 4K10A 3N5HF 3WCCA 5JA0F 4KUXA 3G4FA 2ZY1A 3KROA 3P41A 3LK5A 2Z4WA 3WCMA 3S4JA 3RMGA 4WK5A 5IM1A 3SDTA 5HNAA 2E90A 4LPGF 4LUUA 5JUZF 3WCIA 3NPKA 1DGPA 5DJRF 3WEJA 1WL3A 4H5EF 3DYGA 5DZ2A 3N3LF 2ZCRA 2Z50A 3V1XA 2ONGA 4UMJA 3KRAA 5AELA 5ERMA 3TFNA 2F94F 4LFGA 5E8LA 3CP6A 5DHKA 1VG2A 2H8OA 2E8UA 4XQTF 4P0XA 3KB9A 5EAUA 4E1EA 1YJ4A 3TFPA 3KROB 3DYFA 1HM4A 2ZCOA 3N0FA 3SDUA 1WY0A 1HM7A 1WL0A 3QKCA 1DI1A 2Q9YA 3WCFA 1V4IA 4OKZA 4KK2A 1KIZA 4KFAA 4LFVF 1JFGA 3AQCB 3PKOA 3LGKA 3LZ9A 3OACA 3KRAB 4RYPA 3WEFA 5HN7A 3WE9A 3V66A 2DH4A 4LOBA 4PVXF 4DI5A 5A0KA 4KQUA 3WJNA 4NUAA 5IMPA 4NKFA 3CC9A 4RNQA 5B00A 3QQVA 2ZEUA 5ILHA 3NRIA 5DGMF 2F9KF 5IKAA 2PS6A 2PS8A 3P8LA 4NKEA 2F7MF 3M01A 3LEEA 4KVIA 3RYEA 2E4OA 4JZBA 3LLWA 3LVSA 4FP4A 5JV1F 3TFVA 3N6KF 4JYXA 2Q80A 3N45F 2FORA 3OACB 1V4HA 3G4DA 3AQ0A 3ZOUA 1V4KA 4E9ZA 3SAEA 3VJDA 3P8RA 4MC0A 5EASA 3P5RA 3TC1A 5HN9A 3OABB 3IBAA 2OPMA 2ZCQA 5A0JA 2J5CA 3BNYA 3KRCB 3Q30A 5B02A 1WL1A 4LXWA 2E8TA 4JZXA 3WJKA 4KWDA 5EATA 2E94A 3ZCDA 5I1UA 2PS5A 2FTZA 3P5PA 1ZW5A 4LFEA 1WKZA 4P0VA 4ZQ8A 4OGUA 5B0IA 5C05A 1HXGA 4DZWA 3VJ9A 4Q23A 3WEHA 1VG6A 4EA2A 2Z4YA 5IMIA 1N1BA 2Z52A 4DHDA 5ILIA 1WMWA 2O1OA 5DHIA 1FPSA 4GP2A 3ICNA 4JVJF 1N23A 4GAXA 3WCBA 2E92A 2AZLA 4N1ZF 4XQRF 3ADZA 4LA5A 5CG6A 2AZKA 3M02A 1UBYA 3UCAA 5AYPA 3ZMCA 1YV5A 1N24A 5HN8A 3PH7A 4LTVA 2AEKA 3ACXA 3WCAA 1YYSA 2Q58A 4N9UA 2Z4VA 5KSXF 3WC9A 3VJAA 4LZ0A 1V4JA 2E95A 1VG4A 4L2XF 2E8VA 3WEGA 1UBWA 3N49F 4H5CF 5ER8A 4LZCA 3SDVA 5IKHA 3ACWA 3PYAA 5ILKA 4QPFA 2I19A 3SDQA 4JXYA 3N1WF 3VJCA 3OABA 2F8CF 3ZL6A 3NF2A 5E8KA 3WSAA 4LIXA 3LMDA 3ASXA 1HX9A 3DYHA 3KRCA 4LTZA 2AETA 2ONHA 3AE0A 4LZ3A 2P1CA 4NG6A 1WL2A 5ILJA 3WJOA
chains in the Genus database with same CATH topology
5E8HA 5ERNA 3KRPA 4OKMA 5IMNA 3AQBB 1JFAA 3EZ3A 3PYBA 2Z78A 3MZVA 2E8WA 3EFQA 4KVWA 4E9UA 4JXNA 1YYUA 4DWGA 4LLTA 4RXEA 2E8XA 5IL3A 2F8ZF 1N20A 2PS7A 1V4EA 3LJIA 1UBVA 1RQJA 4KKMA 3APZA 3OYRA 5B0MA 3WCEA 5DGNF 2AZJA 2PS4A 4FJQA 1KIYA 3LGZB 2ZEVA 5DW7A 5IK0A 1VG3A 3MAVA 2RAHA 3NPRA 5B03A 3ACYA 5IK6A 3WCDA 4DWBA 4KQ5A 1N1ZA 1YHLA 2Z4XA 5H9DA 4LA6A 5AFXA 3EGTA 4XQSF 4PVYF 4RXCA 3KRFB 2J1OA 5DJVF 1HXCA 4NFJF 1HXAA 3ICZA 5DJPF 4OMGA 1N22A 3WSBA 3KRPB 4KVDA 5IVGA 2Z7HA 2QISA 5B0KA 3RBMA 3S9VA 3WCLA 5ILDA 2Z4ZA 3LDWA 5JV0F 3B7LA 3CKEA 3LSNA 5JV2F 1YYTA 3ICMA 4RXAA 3ID0A 1YQ7A 5AHUB 3SDRA 2ZCSA 4F6VA 2EWGA 3RYWA 1RTRA 3VJEA 4RXDA 4KPDA 4KPJA 3Q2QA 5B0LA 1UBXA 1N21A 4NFKF 4KVYA 4MC8A 3VJ8A 2F92F 2OGDA 2OA6A 5B01A 3M0GA 4LPHF 3N5JF 5CG5A 4QXSF 3WEIA 1RQIA 4EA0A 2E91A 4NFIF 2AELA 3VJBA 3Q1OA 5A0IA 1PS1A 2E93A 5DGSF 3ZMBA 5EROA 3WCJA 3LG5A 3N1VF 5B0JA 3LOMA 4GP1A 3M9UA 5IK9A 2Z7IA 3KRFA 3BNXA 1VG7A 2OPNA 5ILZA 4HD1A 3W7FA 4EA1A 1YYRA 4H5DF 4GA3A 4F6XA 3V1VA 3TS7A 2VF6A 3WCGA 5IN8A 4KQSA 4OMHA 3N46F 4P0WA 3WCHA 5IL8A 4MC3A 2F89F 1YYQA 1EZFA 3N3DA 3N0GA 4DXJA 4F62A 1YHMA 1YHKA 3IPIA 5DIQF 4LLSA 3ICKA 5ILYA 4DEMF 3KBKA 3PDEA 2J1PA 3Q2ZA 3M00A 3WEKA 2Q9ZA 4K10A 3N5HF 3WCCA 5JA0F 4KUXA 3G4FA 2ZY1A 3KROA 3P41A 3LK5A 2Z4WA 3WCMA 3S4JA 3RMGA 4WK5A 5IM1A 3SDTA 5HNAA 2E90A 4LPGF 4LUUA 5JUZF 3WCIA 3NPKA 1DGPA 5DJRF 3WEJA 1WL3A 4H5EF 3DYGA 5DZ2A 3N3LF 2ZCRA 2Z50A 3V1XA 2ONGA 4UMJA 3KRAA 5AELA 5ERMA 3TFNA 2F94F 4LFGA 5E8LA 3CP6A 5DHKA 1VG2A 2H8OA 2E8UA 4XQTF 4P0XA 3KB9A 5EAUA 4E1EA 1YJ4A 3TFPA 3KROB 3DYFA 1HM4A 2ZCOA 3N0FA 3SDUA 1WY0A 1HM7A 1WL0A 3QKCA 1DI1A 2Q9YA 3WCFA 1V4IA 4OKZA 4KK2A 1KIZA 4KFAA 4LFVF 1JFGA 3AQCB 3PKOA 3LGKA 3LZ9A 3OACA 3KRAB 4RYPA 3WEFA 5HN7A 3WE9A 3V66A 2DH4A 4LOBA 4PVXF 4DI5A 5A0KA 4KQUA 3WJNA 4NUAA 5IMPA 4NKFA 3CC9A 4RNQA 5B00A 3QQVA 2ZEUA 5ILHA 3NRIA 5DGMF 2F9KF 5IKAA 2PS6A 2PS8A 3P8LA 4NKEA 2F7MF 3M01A 3LEEA 4KVIA 3RYEA 2E4OA 4JZBA 3LLWA 3LVSA 4FP4A 5JV1F 3TFVA 3N6KF 4JYXA 2Q80A 3N45F 2FORA 3OACB 1V4HA 3G4DA 3AQ0A 3ZOUA 1V4KA 4E9ZA 3SAEA 3VJDA 3P8RA 4MC0A 5EASA 3P5RA 3TC1A 5HN9A 3OABB 3IBAA 2OPMA 2ZCQA 5A0JA 2J5CA 3BNYA 3KRCB 3Q30A 5B02A 1WL1A 4LXWA 2E8TA 4JZXA 3WJKA 4KWDA 5EATA 2E94A 3ZCDA 5I1UA 2PS5A 2FTZA 3P5PA 1ZW5A 4LFEA 1WKZA 4P0VA 4ZQ8A 4OGUA 5B0IA 5C05A 1HXGA 4DZWA 3VJ9A 4Q23A 3WEHA 1VG6A 4EA2A 2Z4YA 5IMIA 1N1BA 2Z52A 4DHDA 5ILIA 1WMWA 2O1OA 5DHIA 1FPSA 4GP2A 3ICNA 4JVJF 1N23A 4GAXA 3WCBA 2E92A 2AZLA 4N1ZF 4XQRF 3ADZA 4LA5A 5CG6A 2AZKA 3M02A 1UBYA 3UCAA 5AYPA 3ZMCA 1YV5A 1N24A 5HN8A 3PH7A 4LTVA 2AEKA 3ACXA 3WCAA 1YYSA 2Q58A 4N9UA 2Z4VA 5KSXF 3WC9A 3VJAA 4LZ0A 1V4JA 2E95A 1VG4A 4L2XF 2E8VA 3WEGA 1UBWA 3N49F 4H5CF 5ER8A 4LZCA 3SDVA 5IKHA 3ACWA 3PYAA 5ILKA 4QPFA 2I19A 3SDQA 4JXYA 3N1WF 3VJCA 3OABA 2F8CF 3ZL6A 3NF2A 5E8KA 3WSAA 4LIXA 3LMDA 3ASXA 1HX9A 3DYHA 3KRCA 4LTZA 2AETA 2ONHA 3AE0A 4LZ3A 2P1CA 4NG6A 1WL2A 5ILJA 3WJOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5E8H A;  5ERN A;  3KRP A;  4OKM A;  5IMN A;  3AQB B;  1JFA A;  3EZ3 A;  3PYB A;  2Z78 A;  3MZV A;  2E8W A;  3EFQ A;  4KVW A;  4E9U A;  4JXN A;  1YYU A;  4DWG A;  4LLT A;  4RXE A;  2E8X A;  5IL3 A;  2F8Z F;  1N20 A;  2PS7 A;  1V4E A;  3LJI A;  1UBV A;  1RQJ A;  4KKM A;  3APZ A;  3OYR A;  5B0M A;  3WCE A;  5DGN F;  2AZJ A;  2PS4 A;  4FJQ A;  1KIY A;  3LGZ B;  2ZEV A;  5DW7 A;  5IK0 A;  1VG3 A;  3MAV A;  2RAH A;  3NPR A;  5B03 A;  3ACY A;  5IK6 A;  3WCD A;  4DWB A;  4KQ5 A;  1N1Z A;  1YHL A;  2Z4X A;  5H9D A;  4LA6 A;  5AFX A;  3EGT A;  4XQS F;  4PVY F;  4RXC A;  3KRF B;  2J1O A;  5DJV F;  1HXC A;  4NFJ F;  1HXA A;  3ICZ A;  5DJP F;  4OMG A;  1N22 A;  3WSB A;  3KRP B;  4KVD A;  5IVG A;  2Z7H A;  2QIS A;  5B0K A;  3RBM A;  3S9V A;  3WCL A;  5ILD A;  2Z4Z A;  3LDW A;  5JV0 F;  3B7L A;  3CKE A;  3LSN A;  5JV2 F;  1YYT A;  3ICM A;  4RXA A;  3ID0 A;  1YQ7 A;  5AHU B;  3SDR A;  2ZCS A;  4F6V A;  2EWG A;  3RYW A;  1RTR A;  3VJE A;  4RXD A;  4KPD A;  4KPJ A;  3Q2Q A;  5B0L A;  1UBX A;  1N21 A;  4NFK F;  4KVY A;  4MC8 A;  3VJ8 A;  2F92 F;  2OGD A;  2OA6 A;  5B01 A;  3M0G A;  4LPH F;  3N5J F;  5CG5 A;  4QXS F;  3WEI A;  1RQI A;  4EA0 A;  2E91 A;  4NFI F;  2AEL A;  3VJB A;  3Q1O A;  5A0I A;  1PS1 A;  2E93 A;  5DGS F;  3ZMB A;  5ERO A;  3WCJ A;  3LG5 A;  3N1V F;  5B0J A;  3LOM A;  4GP1 A;  3M9U A;  5IK9 A;  2Z7I A;  3KRF A;  3BNX A;  1VG7 A;  2OPN A;  5ILZ A;  4HD1 A;  3W7F A;  4EA1 A;  1YYR A;  4H5D F;  4GA3 A;  4F6X A;  3V1V A;  3TS7 A;  2VF6 A;  3WCG A;  5IN8 A;  4KQS A;  4OMH A;  3N46 F;  4P0W A;  3WCH A;  5IL8 A;  4MC3 A;  2F89 F;  1YYQ A;  1EZF A;  3N3D A;  3N0G A;  4DXJ A;  4F62 A;  1YHM A;  1YHK A;  3IPI A;  5DIQ F;  4LLS A;  3ICK A;  5ILY A;  4DEM F;  3KBK A;  3PDE A;  2J1P A;  3Q2Z A;  3M00 A;  3WEK A;  2Q9Z A;  4K10 A;  3N5H F;  3WCC A;  5JA0 F;  4KUX A;  3G4F A;  2ZY1 A;  3KRO A;  3P41 A;  3LK5 A;  2Z4W A;  3WCM A;  3S4J A;  3RMG A;  4WK5 A;  5IM1 A;  3SDT A;  5HNA A;  2E90 A;  4LPG F;  4LUU A;  5JUZ F;  3WCI A;  3NPK A;  1DGP A;  5DJR F;  3WEJ A;  1WL3 A;  4H5E F;  3DYG A;  5DZ2 A;  3N3L F;  2ZCR A;  2Z50 A;  3V1X A;  2ONG A;  4UMJ A;  3KRA A;  5AEL A;  5ERM A;  3TFN A;  2F94 F;  4LFG A;  5E8L A;  3CP6 A;  5DHK A;  1VG2 A;  2H8O A;  2E8U A;  4XQT F;  4P0X A;  3KB9 A;  5EAU A;  4E1E A;  1YJ4 A;  3TFP A;  3KRO B;  3DYF A;  1HM4 A;  2ZCO A;  3N0F A;  3SDU A;  1WY0 A;  1HM7 A;  1WL0 A;  3QKC A;  1DI1 A;  2Q9Y A;  3WCF A;  1V4I A;  4OKZ A;  4KK2 A;  1KIZ A;  4KFA A;  4LFV F;  1JFG A;  3AQC B;  3PKO A;  3LGK A;  3LZ9 A;  3OAC A;  3KRA B;  4RYP A;  3WEF A;  5HN7 A;  3WE9 A;  3V66 A;  2DH4 A;  4LOB A;  4PVX F;  4DI5 A;  5A0K A;  4KQU A;  3WJN A;  4NUA A;  5IMP A;  4NKF A;  3CC9 A;  4RNQ A;  5B00 A;  3QQV A;  2ZEU A;  5ILH A;  3NRI A;  5DGM F;  2F9K F;  5IKA A;  2PS6 A;  2PS8 A;  3P8L A;  4NKE A;  2F7M F;  3M01 A;  3LEE A;  4KVI A;  3RYE A;  2E4O A;  4JZB A;  3LLW A;  3LVS A;  4FP4 A;  5JV1 F;  3TFV A;  3N6K F;  4JYX A;  2Q80 A;  3N45 F;  2FOR A;  3OAC B;  1V4H A;  3G4D A;  3AQ0 A;  3ZOU A;  1V4K A;  4E9Z A;  3SAE A;  3VJD A;  3P8R A;  4MC0 A;  5EAS A;  3P5R A;  3TC1 A;  5HN9 A;  3OAB B;  3IBA A;  2OPM A;  2ZCQ A;  5A0J A;  2J5C A;  3BNY A;  3KRC B;  3Q30 A;  5B02 A;  1WL1 A;  4LXW A;  2E8T A;  4JZX A;  3WJK A;  4KWD A;  5EAT A;  2E94 A;  3ZCD A;  5I1U A;  2PS5 A;  2FTZ A;  3P5P A;  1ZW5 A;  4LFE A;  1WKZ A;  4P0V A;  4ZQ8 A;  4OGU A;  5B0I A;  5C05 A;  1HXG A;  4DZW A;  3VJ9 A;  4Q23 A;  3WEH A;  1VG6 A;  4EA2 A;  2Z4Y A;  5IMI A;  1N1B A;  2Z52 A;  4DHD A;  5ILI A;  1WMW A;  2O1O A;  5DHI A;  1FPS A;  4GP2 A;  3ICN A;  4JVJ F;  1N23 A;  4GAX A;  3WCB A;  2E92 A;  2AZL A;  4N1Z F;  4XQR F;  3ADZ A;  4LA5 A;  5CG6 A;  2AZK A;  3M02 A;  1UBY A;  3UCA A;  5AYP A;  3ZMC A;  1YV5 A;  1N24 A;  5HN8 A;  3PH7 A;  4LTV A;  2AEK A;  3ACX A;  3WCA A;  1YYS A;  2Q58 A;  4N9U A;  2Z4V A;  5KSX F;  3WC9 A;  3VJA A;  4LZ0 A;  1V4J A;  2E95 A;  1VG4 A;  4L2X F;  2E8V A;  3WEG A;  1UBW A;  3N49 F;  4H5C F;  5ER8 A;  4LZC A;  3SDV A;  5IKH A;  3ACW A;  3PYA A;  5ILK A;  4QPF A;  2I19 A;  3SDQ A;  4JXY A;  3N1W F;  3VJC A;  3OAB A;  2F8C F;  3ZL6 A;  3NF2 A;  5E8K A;  3WSA A;  4LIX A;  3LMD A;  3ASX A;  1HX9 A;  3DYH A;  3KRC A;  4LTZ A;  2AET A;  2ONH A;  3AE0 A;  4LZ3 A;  2P1C A;  4NG6 A;  1WL2 A;  5ILJ A;  3WJO A; 
#chains in the Genus database with same CATH topology
 5E8H A;  5ERN A;  3KRP A;  4OKM A;  5IMN A;  3AQB B;  1JFA A;  3EZ3 A;  3PYB A;  2Z78 A;  3MZV A;  2E8W A;  3EFQ A;  4KVW A;  4E9U A;  4JXN A;  1YYU A;  4DWG A;  4LLT A;  4RXE A;  2E8X A;  5IL3 A;  2F8Z F;  1N20 A;  2PS7 A;  1V4E A;  3LJI A;  1UBV A;  1RQJ A;  4KKM A;  3APZ A;  3OYR A;  5B0M A;  3WCE A;  5DGN F;  2AZJ A;  2PS4 A;  4FJQ A;  1KIY A;  3LGZ B;  2ZEV A;  5DW7 A;  5IK0 A;  1VG3 A;  3MAV A;  2RAH A;  3NPR A;  5B03 A;  3ACY A;  5IK6 A;  3WCD A;  4DWB A;  4KQ5 A;  1N1Z A;  1YHL A;  2Z4X A;  5H9D A;  4LA6 A;  5AFX A;  3EGT A;  4XQS F;  4PVY F;  4RXC A;  3KRF B;  2J1O A;  5DJV F;  1HXC A;  4NFJ F;  1HXA A;  3ICZ A;  5DJP F;  4OMG A;  1N22 A;  3WSB A;  3KRP B;  4KVD A;  5IVG A;  2Z7H A;  2QIS A;  5B0K A;  3RBM A;  3S9V A;  3WCL A;  5ILD A;  2Z4Z A;  3LDW A;  5JV0 F;  3B7L A;  3CKE A;  3LSN A;  5JV2 F;  1YYT A;  3ICM A;  4RXA A;  3ID0 A;  1YQ7 A;  5AHU B;  3SDR A;  2ZCS A;  4F6V A;  2EWG A;  3RYW A;  1RTR A;  3VJE A;  4RXD A;  4KPD A;  4KPJ A;  3Q2Q A;  5B0L A;  1UBX A;  1N21 A;  4NFK F;  4KVY A;  4MC8 A;  3VJ8 A;  2F92 F;  2OGD A;  2OA6 A;  5B01 A;  3M0G A;  4LPH F;  3N5J F;  5CG5 A;  4QXS F;  3WEI A;  1RQI A;  4EA0 A;  2E91 A;  4NFI F;  2AEL A;  3VJB A;  3Q1O A;  5A0I A;  1PS1 A;  2E93 A;  5DGS F;  3ZMB A;  5ERO A;  3WCJ A;  3LG5 A;  3N1V F;  5B0J A;  3LOM A;  4GP1 A;  3M9U A;  5IK9 A;  2Z7I A;  3KRF A;  3BNX A;  1VG7 A;  2OPN A;  5ILZ A;  4HD1 A;  3W7F A;  4EA1 A;  1YYR A;  4H5D F;  4GA3 A;  4F6X A;  3V1V A;  3TS7 A;  2VF6 A;  3WCG A;  5IN8 A;  4KQS A;  4OMH A;  3N46 F;  4P0W A;  3WCH A;  5IL8 A;  4MC3 A;  2F89 F;  1YYQ A;  1EZF A;  3N3D A;  3N0G A;  4DXJ A;  4F62 A;  1YHM A;  1YHK A;  3IPI A;  5DIQ F;  4LLS A;  3ICK A;  5ILY A;  4DEM F;  3KBK A;  3PDE A;  2J1P A;  3Q2Z A;  3M00 A;  3WEK A;  2Q9Z A;  4K10 A;  3N5H F;  3WCC A;  5JA0 F;  4KUX A;  3G4F A;  2ZY1 A;  3KRO A;  3P41 A;  3LK5 A;  2Z4W A;  3WCM A;  3S4J A;  3RMG A;  4WK5 A;  5IM1 A;  3SDT A;  5HNA A;  2E90 A;  4LPG F;  4LUU A;  5JUZ F;  3WCI A;  3NPK A;  1DGP A;  5DJR F;  3WEJ A;  1WL3 A;  4H5E F;  3DYG A;  5DZ2 A;  3N3L F;  2ZCR A;  2Z50 A;  3V1X A;  2ONG A;  4UMJ A;  3KRA A;  5AEL A;  5ERM A;  3TFN A;  2F94 F;  4LFG A;  5E8L A;  3CP6 A;  5DHK A;  1VG2 A;  2H8O A;  2E8U A;  4XQT F;  4P0X A;  3KB9 A;  5EAU A;  4E1E A;  1YJ4 A;  3TFP A;  3KRO B;  3DYF A;  1HM4 A;  2ZCO A;  3N0F A;  3SDU A;  1WY0 A;  1HM7 A;  1WL0 A;  3QKC A;  1DI1 A;  2Q9Y A;  3WCF A;  1V4I A;  4OKZ A;  4KK2 A;  1KIZ A;  4KFA A;  4LFV F;  1JFG A;  3AQC B;  3PKO A;  3LGK A;  3LZ9 A;  3OAC A;  3KRA B;  4RYP A;  3WEF A;  5HN7 A;  3WE9 A;  3V66 A;  2DH4 A;  4LOB A;  4PVX F;  4DI5 A;  5A0K A;  4KQU A;  3WJN A;  4NUA A;  5IMP A;  4NKF A;  3CC9 A;  4RNQ A;  5B00 A;  3QQV A;  2ZEU A;  5ILH A;  3NRI A;  5DGM F;  2F9K F;  5IKA A;  2PS6 A;  2PS8 A;  3P8L A;  4NKE A;  2F7M F;  3M01 A;  3LEE A;  4KVI A;  3RYE A;  2E4O A;  4JZB A;  3LLW A;  3LVS A;  4FP4 A;  5JV1 F;  3TFV A;  3N6K F;  4JYX A;  2Q80 A;  3N45 F;  2FOR A;  3OAC B;  1V4H A;  3G4D A;  3AQ0 A;  3ZOU A;  1V4K A;  4E9Z A;  3SAE A;  3VJD A;  3P8R A;  4MC0 A;  5EAS A;  3P5R A;  3TC1 A;  5HN9 A;  3OAB B;  3IBA A;  2OPM A;  2ZCQ A;  5A0J A;  2J5C A;  3BNY A;  3KRC B;  3Q30 A;  5B02 A;  1WL1 A;  4LXW A;  2E8T A;  4JZX A;  3WJK A;  4KWD A;  5EAT A;  2E94 A;  3ZCD A;  5I1U A;  2PS5 A;  2FTZ A;  3P5P A;  1ZW5 A;  4LFE A;  1WKZ A;  4P0V A;  4ZQ8 A;  4OGU A;  5B0I A;  5C05 A;  1HXG A;  4DZW A;  3VJ9 A;  4Q23 A;  3WEH A;  1VG6 A;  4EA2 A;  2Z4Y A;  5IMI A;  1N1B A;  2Z52 A;  4DHD A;  5ILI A;  1WMW A;  2O1O A;  5DHI A;  1FPS A;  4GP2 A;  3ICN A;  4JVJ F;  1N23 A;  4GAX A;  3WCB A;  2E92 A;  2AZL A;  4N1Z F;  4XQR F;  3ADZ A;  4LA5 A;  5CG6 A;  2AZK A;  3M02 A;  1UBY A;  3UCA A;  5AYP A;  3ZMC A;  1YV5 A;  1N24 A;  5HN8 A;  3PH7 A;  4LTV A;  2AEK A;  3ACX A;  3WCA A;  1YYS A;  2Q58 A;  4N9U A;  2Z4V A;  5KSX F;  3WC9 A;  3VJA A;  4LZ0 A;  1V4J A;  2E95 A;  1VG4 A;  4L2X F;  2E8V A;  3WEG A;  1UBW A;  3N49 F;  4H5C F;  5ER8 A;  4LZC A;  3SDV A;  5IKH A;  3ACW A;  3PYA A;  5ILK A;  4QPF A;  2I19 A;  3SDQ A;  4JXY A;  3N1W F;  3VJC A;  3OAB A;  2F8C F;  3ZL6 A;  3NF2 A;  5E8K A;  3WSA A;  4LIX A;  3LMD A;  3ASX A;  1HX9 A;  3DYH A;  3KRC A;  4LTZ A;  2AET A;  2ONH A;  3AE0 A;  4LZ3 A;  2P1C A;  4NG6 A;  1WL2 A;  5ILJ A;  3WJO A; 
#chains in the Genus database with same CATH homology
 5E8H A;  5ERN A;  3KRP A;  4OKM A;  5IMN A;  3AQB B;  1JFA A;  3EZ3 A;  3PYB A;  2Z78 A;  3MZV A;  2E8W A;  3EFQ A;  4KVW A;  4E9U A;  4JXN A;  1YYU A;  4DWG A;  4LLT A;  4RXE A;  2E8X A;  5IL3 A;  2F8Z F;  1N20 A;  2PS7 A;  1V4E A;  3LJI A;  1UBV A;  1RQJ A;  4KKM A;  3APZ A;  3OYR A;  5B0M A;  3WCE A;  5DGN F;  2AZJ A;  2PS4 A;  4FJQ A;  1KIY A;  3LGZ B;  2ZEV A;  5DW7 A;  5IK0 A;  1VG3 A;  3MAV A;  2RAH A;  3NPR A;  5B03 A;  3ACY A;  5IK6 A;  3WCD A;  4DWB A;  4KQ5 A;  1N1Z A;  1YHL A;  2Z4X A;  5H9D A;  4LA6 A;  5AFX A;  3EGT A;  4XQS F;  4PVY F;  4RXC A;  3KRF B;  2J1O A;  5DJV F;  1HXC A;  4NFJ F;  1HXA A;  3ICZ A;  5DJP F;  4OMG A;  1N22 A;  3WSB A;  3KRP B;  4KVD A;  5IVG A;  2Z7H A;  2QIS A;  5B0K A;  3RBM A;  3S9V A;  3WCL A;  5ILD A;  2Z4Z A;  3LDW A;  5JV0 F;  3B7L A;  3CKE A;  3LSN A;  5JV2 F;  1YYT A;  3ICM A;  4RXA A;  3ID0 A;  1YQ7 A;  5AHU B;  3SDR A;  2ZCS A;  4F6V A;  2EWG A;  3RYW A;  1RTR A;  3VJE A;  4RXD A;  4KPD A;  4KPJ A;  3Q2Q A;  5B0L A;  1UBX A;  1N21 A;  4NFK F;  4KVY A;  4MC8 A;  3VJ8 A;  2F92 F;  2OGD A;  2OA6 A;  5B01 A;  3M0G A;  4LPH F;  3N5J F;  5CG5 A;  4QXS F;  3WEI A;  1RQI A;  4EA0 A;  2E91 A;  4NFI F;  2AEL A;  3VJB A;  3Q1O A;  5A0I A;  1PS1 A;  2E93 A;  5DGS F;  3ZMB A;  5ERO A;  3WCJ A;  3LG5 A;  3N1V F;  5B0J A;  3LOM A;  4GP1 A;  3M9U A;  5IK9 A;  2Z7I A;  3KRF A;  3BNX A;  1VG7 A;  2OPN A;  5ILZ A;  4HD1 A;  3W7F A;  4EA1 A;  1YYR A;  4H5D F;  4GA3 A;  4F6X A;  3V1V A;  3TS7 A;  2VF6 A;  3WCG A;  5IN8 A;  4KQS A;  4OMH A;  3N46 F;  4P0W A;  3WCH A;  5IL8 A;  4MC3 A;  2F89 F;  1YYQ A;  1EZF A;  3N3D A;  3N0G A;  4DXJ A;  4F62 A;  1YHM A;  1YHK A;  3IPI A;  5DIQ F;  4LLS A;  3ICK A;  5ILY A;  4DEM F;  3KBK A;  3PDE A;  2J1P A;  3Q2Z A;  3M00 A;  3WEK A;  2Q9Z A;  4K10 A;  3N5H F;  3WCC A;  5JA0 F;  4KUX A;  3G4F A;  2ZY1 A;  3KRO A;  3P41 A;  3LK5 A;  2Z4W A;  3WCM A;  3S4J A;  3RMG A;  4WK5 A;  5IM1 A;  3SDT A;  5HNA A;  2E90 A;  4LPG F;  4LUU A;  5JUZ F;  3WCI A;  3NPK A;  1DGP A;  5DJR F;  3WEJ A;  1WL3 A;  4H5E F;  3DYG A;  5DZ2 A;  3N3L F;  2ZCR A;  2Z50 A;  3V1X A;  2ONG A;  4UMJ A;  3KRA A;  5AEL A;  5ERM A;  3TFN A;  2F94 F;  4LFG A;  5E8L A;  3CP6 A;  5DHK A;  1VG2 A;  2H8O A;  2E8U A;  4XQT F;  4P0X A;  3KB9 A;  5EAU A;  4E1E A;  1YJ4 A;  3TFP A;  3KRO B;  3DYF A;  1HM4 A;  2ZCO A;  3N0F A;  3SDU A;  1WY0 A;  1HM7 A;  1WL0 A;  3QKC A;  1DI1 A;  2Q9Y A;  3WCF A;  1V4I A;  4OKZ A;  4KK2 A;  1KIZ A;  4KFA A;  4LFV F;  1JFG A;  3AQC B;  3PKO A;  3LGK A;  3LZ9 A;  3OAC A;  3KRA B;  4RYP A;  3WEF A;  5HN7 A;  3WE9 A;  3V66 A;  2DH4 A;  4LOB A;  4PVX F;  4DI5 A;  5A0K A;  4KQU A;  3WJN A;  4NUA A;  5IMP A;  4NKF A;  3CC9 A;  4RNQ A;  5B00 A;  3QQV A;  2ZEU A;  5ILH A;  3NRI A;  5DGM F;  2F9K F;  5IKA A;  2PS6 A;  2PS8 A;  3P8L A;  4NKE A;  2F7M F;  3M01 A;  3LEE A;  4KVI A;  3RYE A;  2E4O A;  4JZB A;  3LLW A;  3LVS A;  4FP4 A;  5JV1 F;  3TFV A;  3N6K F;  4JYX A;  2Q80 A;  3N45 F;  2FOR A;  3OAC B;  1V4H A;  3G4D A;  3AQ0 A;  3ZOU A;  1V4K A;  4E9Z A;  3SAE A;  3VJD A;  3P8R A;  4MC0 A;  5EAS A;  3P5R A;  3TC1 A;  5HN9 A;  3OAB B;  3IBA A;  2OPM A;  2ZCQ A;  5A0J A;  2J5C A;  3BNY A;  3KRC B;  3Q30 A;  5B02 A;  1WL1 A;  4LXW A;  2E8T A;  4JZX A;  3WJK A;  4KWD A;  5EAT A;  2E94 A;  3ZCD A;  5I1U A;  2PS5 A;  2FTZ A;  3P5P A;  1ZW5 A;  4LFE A;  1WKZ A;  4P0V A;  4ZQ8 A;  4OGU A;  5B0I A;  5C05 A;  1HXG A;  4DZW A;  3VJ9 A;  4Q23 A;  3WEH A;  1VG6 A;  4EA2 A;  2Z4Y A;  5IMI A;  1N1B A;  2Z52 A;  4DHD A;  5ILI A;  1WMW A;  2O1O A;  5DHI A;  1FPS A;  4GP2 A;  3ICN A;  4JVJ F;  1N23 A;  4GAX A;  3WCB A;  2E92 A;  2AZL A;  4N1Z F;  4XQR F;  3ADZ A;  4LA5 A;  5CG6 A;  2AZK A;  3M02 A;  1UBY A;  3UCA A;  5AYP A;  3ZMC A;  1YV5 A;  1N24 A;  5HN8 A;  3PH7 A;  4LTV A;  2AEK A;  3ACX A;  3WCA A;  1YYS A;  2Q58 A;  4N9U A;  2Z4V A;  5KSX F;  3WC9 A;  3VJA A;  4LZ0 A;  1V4J A;  2E95 A;  1VG4 A;  4L2X F;  2E8V A;  3WEG A;  1UBW A;  3N49 F;  4H5C F;  5ER8 A;  4LZC A;  3SDV A;  5IKH A;  3ACW A;  3PYA A;  5ILK A;  4QPF A;  2I19 A;  3SDQ A;  4JXY A;  3N1W F;  3VJC A;  3OAB A;  2F8C F;  3ZL6 A;  3NF2 A;  5E8K A;  3WSA A;  4LIX A;  3LMD A;  3ASX A;  1HX9 A;  3DYH A;  3KRC A;  4LTZ A;  2AET A;  2ONH A;  3AE0 A;  4LZ3 A;  2P1C A;  4NG6 A;  1WL2 A;  5ILJ A;  3WJO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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