3ICMA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, mg2+ and 1-(2-hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium
Total Genus 146
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords Farnesyl pyrophosphate synthase
total genus 146
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icmA00
2F89F 1YYTA 4MC3A 3KRPB 2O1OA 3TC1A 5AYPA 3LK5A 5IM1A 2F7MF 5IMPA 3ZL6A 4E1EA 3ID0A 3OABB 3N5HF 1V4KA 3M02A 5ILZA 3BNXA 3G4DA 2Z4VA 3DYGA 1WL2A 4N1ZF 4KVDA 2F8ZF 2Z50A 2PS6A 5B03A 3ZCDA 4P0VA 5AFXA 2FTZA 4LTVA 1YJ4A 3P5RA 1DGPA 2FORA 1V4IA 3G4FA 2Z4XA 4ZQ8A 3PDEA 2E92A 3KB9A 4EA2A 3ASXA 3N6KF 4XQSF 4JZBA 5ERNA 1N1ZA 1JFAA 3P8RA 3LLWA 4RXEA 3MAVA 4GAXA 5DZ2A 3B7LA 3OACB 3P8LA 4H5CF 1KIYA 2ZEUA 2F9KF 5DJRF 3BNYA 3RBMA 1VG2A 3EFQA 3KRPA 3PKOA 2PS7A 4DWBA 1V4EA 2ZCOA 4MC0A 1N23A 5EATA 4RXDA 4XQRF 2Q9ZA 4KQ5A 5B0LA 5DGMF 3N3LF 5IK0A 3OABA 2E94A 3WJNA 5E8KA 2Z7IA 3WCDA 4KPDA 4P0WA 3WCCA 2OA6A 4NFIF 5IK9A 3IBAA 4LLTA 3M01A 5EAUA 3WEFA 3VJEA 2DH4A 1DI1A 4E9UA 5B0JA 2F92F 3TFNA 3N1VF 3M00A 4GA3A 3KBKA 2ONGA 4KQSA 3WEJA 3N1WF 4OGUA 3Q2ZA 4KWDA 2ONHA 5ILJA 4RNQA 1WMWA 1VG7A 4OKZA 5ER8A 5DJVF 3EZ3A 5CG5A 1YV5A 1RTRA 2ZCRA 1HM4A 5A0IA 3V66A 3M9UA 4OMHA 3WJKA 3SAEA 3QKCA 4P0XA 2Z78A 3LVSA 1V4HA 1UBVA 3N49F 1WL1A 4KFAA 3LMDA 3OACA 3WCLA 5IMNA 3SDRA 4JYXA 3LGKA 4EA1A 4LXWA 4NKEA 4F6VA 5IKAA 2H8OA 4KVIA 2PS4A 3N46F 5IL3A 4Q23A 5JUZF 3AE0A 3LG5A 5EASA 1WY0A 3WCBA 3TFVA 4KK2A 4JZXA 4LIXA 5IVGA 3S9VA 2Q58A 4DHDA 2E8UA 2OPMA 3VJBA 3V1VA 4NG6A 4FJQA 4LZ3A 3DYFA 5HN9A 4LTZA 4JXYA 5ILKA 3Q2QA 5DJPF 4QXSF 4LFVF 3LSNA 4KVWA 3CP6A 3NPRA 3NF2A 2EWGA 1UBWA 2J1OA 1YQ7A 1N22A 3N0GA 3ZOUA 5DGSF 5ILDA 4GP2A 3ICZA 4MC8A 2E91A 4PVXF 3UCAA 4F62A 2VF6A 3LOMA 3WCMA 2AELA 5JV0F 5ILYA 4JVJF 2ZY1A 3LEEA 4RXCA 1VG6A 4RYPA 1N20A 3WEHA 1YYRA 3V1XA 2P1CA 4LLSA 2E8WA 1KIZA 2OPNA 4LFEA 3WCEA 4FP4A 4OMGA 2Z52A 2OGDA 3WCAA 1N21A 3ICNA 3WCIA 5B0KA 3KRAB 3M0GA 2E8XA 3NRIA 5C05A 5B02A 3PYAA 4H5EF 4LZ0A 2J5CA 2ZCQA 2PS8A 2AZKA 1HXCA 5IL8A 2ZCSA 1RQJA 5DGNF 3WEIA 2Z4WA 3LDWA 4HD1A 4WK5A 4LPHF 4LOBA 3NPKA 2Z7HA 5AELA 3IPIA 3KRFB 4E9ZA 5ILIA 3ACYA 3DYHA 4LZCA 3WCFA 4DZWA 3VJCA 2J1PA 3SDTA 3LZ9A 5EROA 3WCHA 3SDUA 2Z4ZA 2E95A 3N3DA 5B0IA 5HN7A 3VJ9A 5CG6A 3KROB 5E8HA 5ILHA 3ZMBA 4H5DF 5HNAA 1N24A 4UMJA 5B01A 1V4JA 3ACXA 5DW7A 3KRCB 3P5PA 3APZA 2F8CF 2E93A 5IKHA 3WE9A 3TFPA 2F94F 1N1BA 5HN8A 3LJIA 4NKFA 1HXAA 3KRAA 3CKEA 3ZMCA 3WC9A 5DHIA 5I1UA 3Q1OA 3WCJA 5DIQF 5B0MA 5JV1F 3SDVA 4LFGA 3ICMA 3N45F 2Z4YA 3WSBA 1VG4A 1WKZA 4QPFA 4OKMA 4KKMA 3AQBB 1RQIA 3KRFA 5JA0F 5IN8A 5ERMA 1YYSA 3AQ0A 4JXNA 3ACWA 1EZFA 5A0JA 5B00A 1ZW5A 2AETA 1YHKA 3KROA 5IMIA 4DI5A 5KSXF 4NFJF 3WJOA 5A0KA 3N5JF 3TS7A 3KRCA 3PYBA 3VJ8A 3RMGA 3RYEA 2ZEVA 2AZJA 4GP1A 5DHKA 1JFGA 4NFKF 2PS5A 1VG3A 3Q30A 3OYRA 3ADZA 1YHLA 2E8TA 2Q80A 3WCGA 1YYQA 4DWGA 1UBXA 2E90A 4N9UA 2E4OA 2I19A 1PS1A 4KUXA 4DXJA 2RAHA 2Q9YA 3CC9A 4RXAA 3QQVA 4LA5A 3ICKA 2E8VA 4XQTF 5IK6A 3P41A 1UBYA 4KVYA 1WL0A 4K10A 1HM7A 1YHMA 4KPJA 2AEKA 3SDQA 5E8LA 2QISA 1HXGA 3EGTA 4DEMF 3PH7A 3MZVA 3S4JA 4F6XA 3N0FA 5H9DA 1HX9A 1WL3A 1YYUA 5AHUB 3WEGA 4LA6A 4LUUA 4EA0A 3VJDA 3WSAA 4PVYF 3LGZB 1FPSA 4L2XF 3W7FA 3VJAA 5JV2F 4LPGF 3RYWA 2AZLA 3WEKA 4KQUA 4NUAA 3AQCB
chains in the Genus database with same CATH superfamily
2F89F 1YYTA 4MC3A 3KRPB 2O1OA 3TC1A 5AYPA 3LK5A 5IM1A 2F7MF 5IMPA 3ZL6A 4E1EA 3ID0A 3OABB 3N5HF 1V4KA 3M02A 5ILZA 3BNXA 3G4DA 2Z4VA 3DYGA 1WL2A 4N1ZF 4KVDA 2F8ZF 2Z50A 2PS6A 5B03A 3ZCDA 4P0VA 5AFXA 2FTZA 4LTVA 1YJ4A 3P5RA 1DGPA 2FORA 1V4IA 3G4FA 2Z4XA 4ZQ8A 3PDEA 2E92A 3KB9A 4EA2A 3ASXA 3N6KF 4XQSF 4JZBA 5ERNA 1N1ZA 1JFAA 3P8RA 3LLWA 4RXEA 3MAVA 4GAXA 5DZ2A 3B7LA 3OACB 3P8LA 4H5CF 1KIYA 2ZEUA 2F9KF 5DJRF 3BNYA 3RBMA 1VG2A 3EFQA 3KRPA 3PKOA 2PS7A 4DWBA 1V4EA 2ZCOA 4MC0A 1N23A 5EATA 4RXDA 4XQRF 2Q9ZA 4KQ5A 5B0LA 5DGMF 3N3LF 5IK0A 3OABA 2E94A 3WJNA 5E8KA 2Z7IA 3WCDA 4KPDA 4P0WA 3WCCA 2OA6A 4NFIF 5IK9A 3IBAA 4LLTA 3M01A 5EAUA 3WEFA 3VJEA 2DH4A 1DI1A 4E9UA 5B0JA 2F92F 3TFNA 3N1VF 3M00A 4GA3A 3KBKA 2ONGA 4KQSA 3WEJA 3N1WF 4OGUA 3Q2ZA 4KWDA 2ONHA 5ILJA 4RNQA 1WMWA 1VG7A 4OKZA 5ER8A 5DJVF 3EZ3A 5CG5A 1YV5A 1RTRA 2ZCRA 1HM4A 5A0IA 3V66A 3M9UA 4OMHA 3WJKA 3SAEA 3QKCA 4P0XA 2Z78A 3LVSA 1V4HA 1UBVA 3N49F 1WL1A 4KFAA 3LMDA 3OACA 3WCLA 5IMNA 3SDRA 4JYXA 3LGKA 4EA1A 4LXWA 4NKEA 4F6VA 5IKAA 2H8OA 4KVIA 2PS4A 3N46F 5IL3A 4Q23A 5JUZF 3AE0A 3LG5A 5EASA 1WY0A 3WCBA 3TFVA 4KK2A 4JZXA 4LIXA 5IVGA 3S9VA 2Q58A 4DHDA 2E8UA 2OPMA 3VJBA 3V1VA 4NG6A 4FJQA 4LZ3A 3DYFA 5HN9A 4LTZA 4JXYA 5ILKA 3Q2QA 5DJPF 4QXSF 4LFVF 3LSNA 4KVWA 3CP6A 3NPRA 3NF2A 2EWGA 1UBWA 2J1OA 1YQ7A 1N22A 3N0GA 3ZOUA 5DGSF 5ILDA 4GP2A 3ICZA 4MC8A 2E91A 4PVXF 3UCAA 4F62A 2VF6A 3LOMA 3WCMA 2AELA 5JV0F 5ILYA 4JVJF 2ZY1A 3LEEA 4RXCA 1VG6A 4RYPA 1N20A 3WEHA 1YYRA 3V1XA 2P1CA 4LLSA 2E8WA 1KIZA 2OPNA 4LFEA 3WCEA 4FP4A 4OMGA 2Z52A 2OGDA 3WCAA 1N21A 3ICNA 3WCIA 5B0KA 3KRAB 3M0GA 2E8XA 3NRIA 5C05A 5B02A 3PYAA 4H5EF 4LZ0A 2J5CA 2ZCQA 2PS8A 2AZKA 1HXCA 5IL8A 2ZCSA 1RQJA 5DGNF 3WEIA 2Z4WA 3LDWA 4HD1A 4WK5A 4LPHF 4LOBA 3NPKA 2Z7HA 5AELA 3IPIA 3KRFB 4E9ZA 5ILIA 3ACYA 3DYHA 4LZCA 3WCFA 4DZWA 3VJCA 2J1PA 3SDTA 3LZ9A 5EROA 3WCHA 3SDUA 2Z4ZA 2E95A 3N3DA 5B0IA 5HN7A 3VJ9A 5CG6A 3KROB 5E8HA 5ILHA 3ZMBA 4H5DF 5HNAA 1N24A 4UMJA 5B01A 1V4JA 3ACXA 5DW7A 3KRCB 3P5PA 3APZA 2F8CF 2E93A 5IKHA 3WE9A 3TFPA 2F94F 1N1BA 5HN8A 3LJIA 4NKFA 1HXAA 3KRAA 3CKEA 3ZMCA 3WC9A 5DHIA 5I1UA 3Q1OA 3WCJA 5DIQF 5B0MA 5JV1F 3SDVA 4LFGA 3ICMA 3N45F 2Z4YA 3WSBA 1VG4A 1WKZA 4QPFA 4OKMA 4KKMA 3AQBB 1RQIA 3KRFA 5JA0F 5IN8A 5ERMA 1YYSA 3AQ0A 4JXNA 3ACWA 1EZFA 5A0JA 5B00A 1ZW5A 2AETA 1YHKA 3KROA 5IMIA 4DI5A 5KSXF 4NFJF 3WJOA 5A0KA 3N5JF 3TS7A 3KRCA 3PYBA 3VJ8A 3RMGA 3RYEA 2ZEVA 2AZJA 4GP1A 5DHKA 1JFGA 4NFKF 2PS5A 1VG3A 3Q30A 3OYRA 3ADZA 1YHLA 2E8TA 2Q80A 3WCGA 1YYQA 4DWGA 1UBXA 2E90A 4N9UA 2E4OA 2I19A 1PS1A 4KUXA 4DXJA 2RAHA 2Q9YA 3CC9A 4RXAA 3QQVA 4LA5A 3ICKA 2E8VA 4XQTF 5IK6A 3P41A 1UBYA 4KVYA 1WL0A 4K10A 1HM7A 1YHMA 4KPJA 2AEKA 3SDQA 5E8LA 2QISA 1HXGA 3EGTA 4DEMF 3PH7A 3MZVA 3S4JA 4F6XA 3N0FA 5H9DA 1HX9A 1WL3A 1YYUA 5AHUB 3WEGA 4LA6A 4LUUA 4EA0A 3VJDA 3WSAA 4PVYF 3LGZB 1FPSA 4L2XF 3W7FA 3VJAA 5JV2F 4LPGF 3RYWA 2AZLA 3WEKA 4KQUA 4NUAA 3AQCB
chains in the Genus database with same CATH topology
2F89F 1YYTA 4MC3A 3KRPB 2O1OA 3TC1A 5AYPA 3LK5A 5IM1A 2F7MF 5IMPA 3ZL6A 4E1EA 3ID0A 3OABB 3N5HF 1V4KA 3M02A 5ILZA 3BNXA 3G4DA 2Z4VA 3DYGA 1WL2A 4N1ZF 4KVDA 2F8ZF 2Z50A 2PS6A 5B03A 3ZCDA 4P0VA 5AFXA 2FTZA 4LTVA 1YJ4A 3P5RA 1DGPA 2FORA 1V4IA 3G4FA 2Z4XA 4ZQ8A 3PDEA 2E92A 3KB9A 4EA2A 3ASXA 3N6KF 4XQSF 4JZBA 5ERNA 1N1ZA 1JFAA 3P8RA 3LLWA 4RXEA 3MAVA 4GAXA 5DZ2A 3B7LA 3OACB 3P8LA 4H5CF 1KIYA 2ZEUA 2F9KF 5DJRF 3BNYA 3RBMA 1VG2A 3EFQA 3KRPA 3PKOA 2PS7A 4DWBA 1V4EA 2ZCOA 4MC0A 1N23A 5EATA 4RXDA 4XQRF 2Q9ZA 4KQ5A 5B0LA 5DGMF 3N3LF 5IK0A 3OABA 2E94A 3WJNA 5E8KA 2Z7IA 3WCDA 4KPDA 4P0WA 3WCCA 2OA6A 4NFIF 5IK9A 3IBAA 4LLTA 3M01A 5EAUA 3WEFA 3VJEA 2DH4A 1DI1A 4E9UA 5B0JA 2F92F 3TFNA 3N1VF 3M00A 4GA3A 3KBKA 2ONGA 4KQSA 3WEJA 3N1WF 4OGUA 3Q2ZA 4KWDA 2ONHA 5ILJA 4RNQA 1WMWA 1VG7A 4OKZA 5ER8A 5DJVF 3EZ3A 5CG5A 1YV5A 1RTRA 2ZCRA 1HM4A 5A0IA 3V66A 3M9UA 4OMHA 3WJKA 3SAEA 3QKCA 4P0XA 2Z78A 3LVSA 1V4HA 1UBVA 3N49F 1WL1A 4KFAA 3LMDA 3OACA 3WCLA 5IMNA 3SDRA 4JYXA 3LGKA 4EA1A 4LXWA 4NKEA 4F6VA 5IKAA 2H8OA 4KVIA 2PS4A 3N46F 5IL3A 4Q23A 5JUZF 3AE0A 3LG5A 5EASA 1WY0A 3WCBA 3TFVA 4KK2A 4JZXA 4LIXA 5IVGA 3S9VA 2Q58A 4DHDA 2E8UA 2OPMA 3VJBA 3V1VA 4NG6A 4FJQA 4LZ3A 3DYFA 5HN9A 4LTZA 4JXYA 5ILKA 3Q2QA 5DJPF 4QXSF 4LFVF 3LSNA 4KVWA 3CP6A 3NPRA 3NF2A 2EWGA 1UBWA 2J1OA 1YQ7A 1N22A 3N0GA 3ZOUA 5DGSF 5ILDA 4GP2A 3ICZA 4MC8A 2E91A 4PVXF 3UCAA 4F62A 2VF6A 3LOMA 3WCMA 2AELA 5JV0F 5ILYA 4JVJF 2ZY1A 3LEEA 4RXCA 1VG6A 4RYPA 1N20A 3WEHA 1YYRA 3V1XA 2P1CA 4LLSA 2E8WA 1KIZA 2OPNA 4LFEA 3WCEA 4FP4A 4OMGA 2Z52A 2OGDA 3WCAA 1N21A 3ICNA 3WCIA 5B0KA 3KRAB 3M0GA 2E8XA 3NRIA 5C05A 5B02A 3PYAA 4H5EF 4LZ0A 2J5CA 2ZCQA 2PS8A 2AZKA 1HXCA 5IL8A 2ZCSA 1RQJA 5DGNF 3WEIA 2Z4WA 3LDWA 4HD1A 4WK5A 4LPHF 4LOBA 3NPKA 2Z7HA 5AELA 3IPIA 3KRFB 4E9ZA 5ILIA 3ACYA 3DYHA 4LZCA 3WCFA 4DZWA 3VJCA 2J1PA 3SDTA 3LZ9A 5EROA 3WCHA 3SDUA 2Z4ZA 2E95A 3N3DA 5B0IA 5HN7A 3VJ9A 5CG6A 3KROB 5E8HA 5ILHA 3ZMBA 4H5DF 5HNAA 1N24A 4UMJA 5B01A 1V4JA 3ACXA 5DW7A 3KRCB 3P5PA 3APZA 2F8CF 2E93A 5IKHA 3WE9A 3TFPA 2F94F 1N1BA 5HN8A 3LJIA 4NKFA 1HXAA 3KRAA 3CKEA 3ZMCA 3WC9A 5DHIA 5I1UA 3Q1OA 3WCJA 5DIQF 5B0MA 5JV1F 3SDVA 4LFGA 3ICMA 3N45F 2Z4YA 3WSBA 1VG4A 1WKZA 4QPFA 4OKMA 4KKMA 3AQBB 1RQIA 3KRFA 5JA0F 5IN8A 5ERMA 1YYSA 3AQ0A 4JXNA 3ACWA 1EZFA 5A0JA 5B00A 1ZW5A 2AETA 1YHKA 3KROA 5IMIA 4DI5A 5KSXF 4NFJF 3WJOA 5A0KA 3N5JF 3TS7A 3KRCA 3PYBA 3VJ8A 3RMGA 3RYEA 2ZEVA 2AZJA 4GP1A 5DHKA 1JFGA 4NFKF 2PS5A 1VG3A 3Q30A 3OYRA 3ADZA 1YHLA 2E8TA 2Q80A 3WCGA 1YYQA 4DWGA 1UBXA 2E90A 4N9UA 2E4OA 2I19A 1PS1A 4KUXA 4DXJA 2RAHA 2Q9YA 3CC9A 4RXAA 3QQVA 4LA5A 3ICKA 2E8VA 4XQTF 5IK6A 3P41A 1UBYA 4KVYA 1WL0A 4K10A 1HM7A 1YHMA 4KPJA 2AEKA 3SDQA 5E8LA 2QISA 1HXGA 3EGTA 4DEMF 3PH7A 3MZVA 3S4JA 4F6XA 3N0FA 5H9DA 1HX9A 1WL3A 1YYUA 5AHUB 3WEGA 4LA6A 4LUUA 4EA0A 3VJDA 3WSAA 4PVYF 3LGZB 1FPSA 4L2XF 3W7FA 3VJAA 5JV2F 4LPGF 3RYWA 2AZLA 3WEKA 4KQUA 4NUAA 3AQCB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F89 F;  1YYT A;  4MC3 A;  3KRP B;  2O1O A;  3TC1 A;  5AYP A;  3LK5 A;  5IM1 A;  2F7M F;  5IMP A;  3ZL6 A;  4E1E A;  3ID0 A;  3OAB B;  3N5H F;  1V4K A;  3M02 A;  5ILZ A;  3BNX A;  3G4D A;  2Z4V A;  3DYG A;  1WL2 A;  4N1Z F;  4KVD A;  2F8Z F;  2Z50 A;  2PS6 A;  5B03 A;  3ZCD A;  4P0V A;  5AFX A;  2FTZ A;  4LTV A;  1YJ4 A;  3P5R A;  1DGP A;  2FOR A;  1V4I A;  3G4F A;  2Z4X A;  4ZQ8 A;  3PDE A;  2E92 A;  3KB9 A;  4EA2 A;  3ASX A;  3N6K F;  4XQS F;  4JZB A;  5ERN A;  1N1Z A;  1JFA A;  3P8R A;  3LLW A;  4RXE A;  3MAV A;  4GAX A;  5DZ2 A;  3B7L A;  3OAC B;  3P8L A;  4H5C F;  1KIY A;  2ZEU A;  2F9K F;  5DJR F;  3BNY A;  3RBM A;  1VG2 A;  3EFQ A;  3KRP A;  3PKO A;  2PS7 A;  4DWB A;  1V4E A;  2ZCO A;  4MC0 A;  1N23 A;  5EAT A;  4RXD A;  4XQR F;  2Q9Z A;  4KQ5 A;  5B0L A;  5DGM F;  3N3L F;  5IK0 A;  3OAB A;  2E94 A;  3WJN A;  5E8K A;  2Z7I A;  3WCD A;  4KPD A;  4P0W A;  3WCC A;  2OA6 A;  4NFI F;  5IK9 A;  3IBA A;  4LLT A;  3M01 A;  5EAU A;  3WEF A;  3VJE A;  2DH4 A;  1DI1 A;  4E9U A;  5B0J A;  2F92 F;  3TFN A;  3N1V F;  3M00 A;  4GA3 A;  3KBK A;  2ONG A;  4KQS A;  3WEJ A;  3N1W F;  4OGU A;  3Q2Z A;  4KWD A;  2ONH A;  5ILJ A;  4RNQ A;  1WMW A;  1VG7 A;  4OKZ A;  5ER8 A;  5DJV F;  3EZ3 A;  5CG5 A;  1YV5 A;  1RTR A;  2ZCR A;  1HM4 A;  5A0I A;  3V66 A;  3M9U A;  4OMH A;  3WJK A;  3SAE A;  3QKC A;  4P0X A;  2Z78 A;  3LVS A;  1V4H A;  1UBV A;  3N49 F;  1WL1 A;  4KFA A;  3LMD A;  3OAC A;  3WCL A;  5IMN A;  3SDR A;  4JYX A;  3LGK A;  4EA1 A;  4LXW A;  4NKE A;  4F6V A;  5IKA A;  2H8O A;  4KVI A;  2PS4 A;  3N46 F;  5IL3 A;  4Q23 A;  5JUZ F;  3AE0 A;  3LG5 A;  5EAS A;  1WY0 A;  3WCB A;  3TFV A;  4KK2 A;  4JZX A;  4LIX A;  5IVG A;  3S9V A;  2Q58 A;  4DHD A;  2E8U A;  2OPM A;  3VJB A;  3V1V A;  4NG6 A;  4FJQ A;  4LZ3 A;  3DYF A;  5HN9 A;  4LTZ A;  4JXY A;  5ILK A;  3Q2Q A;  5DJP F;  4QXS F;  4LFV F;  3LSN A;  4KVW A;  3CP6 A;  3NPR A;  3NF2 A;  2EWG A;  1UBW A;  2J1O A;  1YQ7 A;  1N22 A;  3N0G A;  3ZOU A;  5DGS F;  5ILD A;  4GP2 A;  3ICZ A;  4MC8 A;  2E91 A;  4PVX F;  3UCA A;  4F62 A;  2VF6 A;  3LOM A;  3WCM A;  2AEL A;  5JV0 F;  5ILY A;  4JVJ F;  2ZY1 A;  3LEE A;  4RXC A;  1VG6 A;  4RYP A;  1N20 A;  3WEH A;  1YYR A;  3V1X A;  2P1C A;  4LLS A;  2E8W A;  1KIZ A;  2OPN A;  4LFE A;  3WCE A;  4FP4 A;  4OMG A;  2Z52 A;  2OGD A;  3WCA A;  1N21 A;  3ICN A;  3WCI A;  5B0K A;  3KRA B;  3M0G A;  2E8X A;  3NRI A;  5C05 A;  5B02 A;  3PYA A;  4H5E F;  4LZ0 A;  2J5C A;  2ZCQ A;  2PS8 A;  2AZK A;  1HXC A;  5IL8 A;  2ZCS A;  1RQJ A;  5DGN F;  3WEI A;  2Z4W A;  3LDW A;  4HD1 A;  4WK5 A;  4LPH F;  4LOB A;  3NPK A;  2Z7H A;  5AEL A;  3IPI A;  3KRF B;  4E9Z A;  5ILI A;  3ACY A;  3DYH A;  4LZC A;  3WCF A;  4DZW A;  3VJC A;  2J1P A;  3SDT A;  3LZ9 A;  5ERO A;  3WCH A;  3SDU A;  2Z4Z A;  2E95 A;  3N3D A;  5B0I A;  5HN7 A;  3VJ9 A;  5CG6 A;  3KRO B;  5E8H A;  5ILH A;  3ZMB A;  4H5D F;  5HNA A;  1N24 A;  4UMJ A;  5B01 A;  1V4J A;  3ACX A;  5DW7 A;  3KRC B;  3P5P A;  3APZ A;  2F8C F;  2E93 A;  5IKH A;  3WE9 A;  3TFP A;  2F94 F;  1N1B A;  5HN8 A;  3LJI A;  4NKF A;  1HXA A;  3KRA A;  3CKE A;  3ZMC A;  3WC9 A;  5DHI A;  5I1U A;  3Q1O A;  3WCJ A;  5DIQ F;  5B0M A;  5JV1 F;  3SDV A;  4LFG A;  3ICM A;  3N45 F;  2Z4Y A;  3WSB A;  1VG4 A;  1WKZ A;  4QPF A;  4OKM A;  4KKM A;  3AQB B;  1RQI A;  3KRF A;  5JA0 F;  5IN8 A;  5ERM A;  1YYS A;  3AQ0 A;  4JXN A;  3ACW A;  1EZF A;  5A0J A;  5B00 A;  1ZW5 A;  2AET A;  1YHK A;  3KRO A;  5IMI A;  4DI5 A;  5KSX F;  4NFJ F;  3WJO A;  5A0K A;  3N5J F;  3TS7 A;  3KRC A;  3PYB A;  3VJ8 A;  3RMG A;  3RYE A;  2ZEV A;  2AZJ A;  4GP1 A;  5DHK A;  1JFG A;  4NFK F;  2PS5 A;  1VG3 A;  3Q30 A;  3OYR A;  3ADZ A;  1YHL A;  2E8T A;  2Q80 A;  3WCG A;  1YYQ A;  4DWG A;  1UBX A;  2E90 A;  4N9U A;  2E4O A;  2I19 A;  1PS1 A;  4KUX A;  4DXJ A;  2RAH A;  2Q9Y A;  3CC9 A;  4RXA A;  3QQV A;  4LA5 A;  3ICK A;  2E8V A;  4XQT F;  5IK6 A;  3P41 A;  1UBY A;  4KVY A;  1WL0 A;  4K10 A;  1HM7 A;  1YHM A;  4KPJ A;  2AEK A;  3SDQ A;  5E8L A;  2QIS A;  1HXG A;  3EGT A;  4DEM F;  3PH7 A;  3MZV A;  3S4J A;  4F6X A;  3N0F A;  5H9D A;  1HX9 A;  1WL3 A;  1YYU A;  5AHU B;  3WEG A;  4LA6 A;  4LUU A;  4EA0 A;  3VJD A;  3WSA A;  4PVY F;  3LGZ B;  1FPS A;  4L2X F;  3W7F A;  3VJA A;  5JV2 F;  4LPG F;  3RYW A;  2AZL A;  3WEK A;  4KQU A;  4NUA A;  3AQC B; 
#chains in the Genus database with same CATH topology
 2F89 F;  1YYT A;  4MC3 A;  3KRP B;  2O1O A;  3TC1 A;  5AYP A;  3LK5 A;  5IM1 A;  2F7M F;  5IMP A;  3ZL6 A;  4E1E A;  3ID0 A;  3OAB B;  3N5H F;  1V4K A;  3M02 A;  5ILZ A;  3BNX A;  3G4D A;  2Z4V A;  3DYG A;  1WL2 A;  4N1Z F;  4KVD A;  2F8Z F;  2Z50 A;  2PS6 A;  5B03 A;  3ZCD A;  4P0V A;  5AFX A;  2FTZ A;  4LTV A;  1YJ4 A;  3P5R A;  1DGP A;  2FOR A;  1V4I A;  3G4F A;  2Z4X A;  4ZQ8 A;  3PDE A;  2E92 A;  3KB9 A;  4EA2 A;  3ASX A;  3N6K F;  4XQS F;  4JZB A;  5ERN A;  1N1Z A;  1JFA A;  3P8R A;  3LLW A;  4RXE A;  3MAV A;  4GAX A;  5DZ2 A;  3B7L A;  3OAC B;  3P8L A;  4H5C F;  1KIY A;  2ZEU A;  2F9K F;  5DJR F;  3BNY A;  3RBM A;  1VG2 A;  3EFQ A;  3KRP A;  3PKO A;  2PS7 A;  4DWB A;  1V4E A;  2ZCO A;  4MC0 A;  1N23 A;  5EAT A;  4RXD A;  4XQR F;  2Q9Z A;  4KQ5 A;  5B0L A;  5DGM F;  3N3L F;  5IK0 A;  3OAB A;  2E94 A;  3WJN A;  5E8K A;  2Z7I A;  3WCD A;  4KPD A;  4P0W A;  3WCC A;  2OA6 A;  4NFI F;  5IK9 A;  3IBA A;  4LLT A;  3M01 A;  5EAU A;  3WEF A;  3VJE A;  2DH4 A;  1DI1 A;  4E9U A;  5B0J A;  2F92 F;  3TFN A;  3N1V F;  3M00 A;  4GA3 A;  3KBK A;  2ONG A;  4KQS A;  3WEJ A;  3N1W F;  4OGU A;  3Q2Z A;  4KWD A;  2ONH A;  5ILJ A;  4RNQ A;  1WMW A;  1VG7 A;  4OKZ A;  5ER8 A;  5DJV F;  3EZ3 A;  5CG5 A;  1YV5 A;  1RTR A;  2ZCR A;  1HM4 A;  5A0I A;  3V66 A;  3M9U A;  4OMH A;  3WJK A;  3SAE A;  3QKC A;  4P0X A;  2Z78 A;  3LVS A;  1V4H A;  1UBV A;  3N49 F;  1WL1 A;  4KFA A;  3LMD A;  3OAC A;  3WCL A;  5IMN A;  3SDR A;  4JYX A;  3LGK A;  4EA1 A;  4LXW A;  4NKE A;  4F6V A;  5IKA A;  2H8O A;  4KVI A;  2PS4 A;  3N46 F;  5IL3 A;  4Q23 A;  5JUZ F;  3AE0 A;  3LG5 A;  5EAS A;  1WY0 A;  3WCB A;  3TFV A;  4KK2 A;  4JZX A;  4LIX A;  5IVG A;  3S9V A;  2Q58 A;  4DHD A;  2E8U A;  2OPM A;  3VJB A;  3V1V A;  4NG6 A;  4FJQ A;  4LZ3 A;  3DYF A;  5HN9 A;  4LTZ A;  4JXY A;  5ILK A;  3Q2Q A;  5DJP F;  4QXS F;  4LFV F;  3LSN A;  4KVW A;  3CP6 A;  3NPR A;  3NF2 A;  2EWG A;  1UBW A;  2J1O A;  1YQ7 A;  1N22 A;  3N0G A;  3ZOU A;  5DGS F;  5ILD A;  4GP2 A;  3ICZ A;  4MC8 A;  2E91 A;  4PVX F;  3UCA A;  4F62 A;  2VF6 A;  3LOM A;  3WCM A;  2AEL A;  5JV0 F;  5ILY A;  4JVJ F;  2ZY1 A;  3LEE A;  4RXC A;  1VG6 A;  4RYP A;  1N20 A;  3WEH A;  1YYR A;  3V1X A;  2P1C A;  4LLS A;  2E8W A;  1KIZ A;  2OPN A;  4LFE A;  3WCE A;  4FP4 A;  4OMG A;  2Z52 A;  2OGD A;  3WCA A;  1N21 A;  3ICN A;  3WCI A;  5B0K A;  3KRA B;  3M0G A;  2E8X A;  3NRI A;  5C05 A;  5B02 A;  3PYA A;  4H5E F;  4LZ0 A;  2J5C A;  2ZCQ A;  2PS8 A;  2AZK A;  1HXC A;  5IL8 A;  2ZCS A;  1RQJ A;  5DGN F;  3WEI A;  2Z4W A;  3LDW A;  4HD1 A;  4WK5 A;  4LPH F;  4LOB A;  3NPK A;  2Z7H A;  5AEL A;  3IPI A;  3KRF B;  4E9Z A;  5ILI A;  3ACY A;  3DYH A;  4LZC A;  3WCF A;  4DZW A;  3VJC A;  2J1P A;  3SDT A;  3LZ9 A;  5ERO A;  3WCH A;  3SDU A;  2Z4Z A;  2E95 A;  3N3D A;  5B0I A;  5HN7 A;  3VJ9 A;  5CG6 A;  3KRO B;  5E8H A;  5ILH A;  3ZMB A;  4H5D F;  5HNA A;  1N24 A;  4UMJ A;  5B01 A;  1V4J A;  3ACX A;  5DW7 A;  3KRC B;  3P5P A;  3APZ A;  2F8C F;  2E93 A;  5IKH A;  3WE9 A;  3TFP A;  2F94 F;  1N1B A;  5HN8 A;  3LJI A;  4NKF A;  1HXA A;  3KRA A;  3CKE A;  3ZMC A;  3WC9 A;  5DHI A;  5I1U A;  3Q1O A;  3WCJ A;  5DIQ F;  5B0M A;  5JV1 F;  3SDV A;  4LFG A;  3ICM A;  3N45 F;  2Z4Y A;  3WSB A;  1VG4 A;  1WKZ A;  4QPF A;  4OKM A;  4KKM A;  3AQB B;  1RQI A;  3KRF A;  5JA0 F;  5IN8 A;  5ERM A;  1YYS A;  3AQ0 A;  4JXN A;  3ACW A;  1EZF A;  5A0J A;  5B00 A;  1ZW5 A;  2AET A;  1YHK A;  3KRO A;  5IMI A;  4DI5 A;  5KSX F;  4NFJ F;  3WJO A;  5A0K A;  3N5J F;  3TS7 A;  3KRC A;  3PYB A;  3VJ8 A;  3RMG A;  3RYE A;  2ZEV A;  2AZJ A;  4GP1 A;  5DHK A;  1JFG A;  4NFK F;  2PS5 A;  1VG3 A;  3Q30 A;  3OYR A;  3ADZ A;  1YHL A;  2E8T A;  2Q80 A;  3WCG A;  1YYQ A;  4DWG A;  1UBX A;  2E90 A;  4N9U A;  2E4O A;  2I19 A;  1PS1 A;  4KUX A;  4DXJ A;  2RAH A;  2Q9Y A;  3CC9 A;  4RXA A;  3QQV A;  4LA5 A;  3ICK A;  2E8V A;  4XQT F;  5IK6 A;  3P41 A;  1UBY A;  4KVY A;  1WL0 A;  4K10 A;  1HM7 A;  1YHM A;  4KPJ A;  2AEK A;  3SDQ A;  5E8L A;  2QIS A;  1HXG A;  3EGT A;  4DEM F;  3PH7 A;  3MZV A;  3S4J A;  4F6X A;  3N0F A;  5H9D A;  1HX9 A;  1WL3 A;  1YYU A;  5AHU B;  3WEG A;  4LA6 A;  4LUU A;  4EA0 A;  3VJD A;  3WSA A;  4PVY F;  3LGZ B;  1FPS A;  4L2X F;  3W7F A;  3VJA A;  5JV2 F;  4LPG F;  3RYW A;  2AZL A;  3WEK A;  4KQU A;  4NUA A;  3AQC B; 
#chains in the Genus database with same CATH homology
 2F89 F;  1YYT A;  4MC3 A;  3KRP B;  2O1O A;  3TC1 A;  5AYP A;  3LK5 A;  5IM1 A;  2F7M F;  5IMP A;  3ZL6 A;  4E1E A;  3ID0 A;  3OAB B;  3N5H F;  1V4K A;  3M02 A;  5ILZ A;  3BNX A;  3G4D A;  2Z4V A;  3DYG A;  1WL2 A;  4N1Z F;  4KVD A;  2F8Z F;  2Z50 A;  2PS6 A;  5B03 A;  3ZCD A;  4P0V A;  5AFX A;  2FTZ A;  4LTV A;  1YJ4 A;  3P5R A;  1DGP A;  2FOR A;  1V4I A;  3G4F A;  2Z4X A;  4ZQ8 A;  3PDE A;  2E92 A;  3KB9 A;  4EA2 A;  3ASX A;  3N6K F;  4XQS F;  4JZB A;  5ERN A;  1N1Z A;  1JFA A;  3P8R A;  3LLW A;  4RXE A;  3MAV A;  4GAX A;  5DZ2 A;  3B7L A;  3OAC B;  3P8L A;  4H5C F;  1KIY A;  2ZEU A;  2F9K F;  5DJR F;  3BNY A;  3RBM A;  1VG2 A;  3EFQ A;  3KRP A;  3PKO A;  2PS7 A;  4DWB A;  1V4E A;  2ZCO A;  4MC0 A;  1N23 A;  5EAT A;  4RXD A;  4XQR F;  2Q9Z A;  4KQ5 A;  5B0L A;  5DGM F;  3N3L F;  5IK0 A;  3OAB A;  2E94 A;  3WJN A;  5E8K A;  2Z7I A;  3WCD A;  4KPD A;  4P0W A;  3WCC A;  2OA6 A;  4NFI F;  5IK9 A;  3IBA A;  4LLT A;  3M01 A;  5EAU A;  3WEF A;  3VJE A;  2DH4 A;  1DI1 A;  4E9U A;  5B0J A;  2F92 F;  3TFN A;  3N1V F;  3M00 A;  4GA3 A;  3KBK A;  2ONG A;  4KQS A;  3WEJ A;  3N1W F;  4OGU A;  3Q2Z A;  4KWD A;  2ONH A;  5ILJ A;  4RNQ A;  1WMW A;  1VG7 A;  4OKZ A;  5ER8 A;  5DJV F;  3EZ3 A;  5CG5 A;  1YV5 A;  1RTR A;  2ZCR A;  1HM4 A;  5A0I A;  3V66 A;  3M9U A;  4OMH A;  3WJK A;  3SAE A;  3QKC A;  4P0X A;  2Z78 A;  3LVS A;  1V4H A;  1UBV A;  3N49 F;  1WL1 A;  4KFA A;  3LMD A;  3OAC A;  3WCL A;  5IMN A;  3SDR A;  4JYX A;  3LGK A;  4EA1 A;  4LXW A;  4NKE A;  4F6V A;  5IKA A;  2H8O A;  4KVI A;  2PS4 A;  3N46 F;  5IL3 A;  4Q23 A;  5JUZ F;  3AE0 A;  3LG5 A;  5EAS A;  1WY0 A;  3WCB A;  3TFV A;  4KK2 A;  4JZX A;  4LIX A;  5IVG A;  3S9V A;  2Q58 A;  4DHD A;  2E8U A;  2OPM A;  3VJB A;  3V1V A;  4NG6 A;  4FJQ A;  4LZ3 A;  3DYF A;  5HN9 A;  4LTZ A;  4JXY A;  5ILK A;  3Q2Q A;  5DJP F;  4QXS F;  4LFV F;  3LSN A;  4KVW A;  3CP6 A;  3NPR A;  3NF2 A;  2EWG A;  1UBW A;  2J1O A;  1YQ7 A;  1N22 A;  3N0G A;  3ZOU A;  5DGS F;  5ILD A;  4GP2 A;  3ICZ A;  4MC8 A;  2E91 A;  4PVX F;  3UCA A;  4F62 A;  2VF6 A;  3LOM A;  3WCM A;  2AEL A;  5JV0 F;  5ILY A;  4JVJ F;  2ZY1 A;  3LEE A;  4RXC A;  1VG6 A;  4RYP A;  1N20 A;  3WEH A;  1YYR A;  3V1X A;  2P1C A;  4LLS A;  2E8W A;  1KIZ A;  2OPN A;  4LFE A;  3WCE A;  4FP4 A;  4OMG A;  2Z52 A;  2OGD A;  3WCA A;  1N21 A;  3ICN A;  3WCI A;  5B0K A;  3KRA B;  3M0G A;  2E8X A;  3NRI A;  5C05 A;  5B02 A;  3PYA A;  4H5E F;  4LZ0 A;  2J5C A;  2ZCQ A;  2PS8 A;  2AZK A;  1HXC A;  5IL8 A;  2ZCS A;  1RQJ A;  5DGN F;  3WEI A;  2Z4W A;  3LDW A;  4HD1 A;  4WK5 A;  4LPH F;  4LOB A;  3NPK A;  2Z7H A;  5AEL A;  3IPI A;  3KRF B;  4E9Z A;  5ILI A;  3ACY A;  3DYH A;  4LZC A;  3WCF A;  4DZW A;  3VJC A;  2J1P A;  3SDT A;  3LZ9 A;  5ERO A;  3WCH A;  3SDU A;  2Z4Z A;  2E95 A;  3N3D A;  5B0I A;  5HN7 A;  3VJ9 A;  5CG6 A;  3KRO B;  5E8H A;  5ILH A;  3ZMB A;  4H5D F;  5HNA A;  1N24 A;  4UMJ A;  5B01 A;  1V4J A;  3ACX A;  5DW7 A;  3KRC B;  3P5P A;  3APZ A;  2F8C F;  2E93 A;  5IKH A;  3WE9 A;  3TFP A;  2F94 F;  1N1B A;  5HN8 A;  3LJI A;  4NKF A;  1HXA A;  3KRA A;  3CKE A;  3ZMC A;  3WC9 A;  5DHI A;  5I1U A;  3Q1O A;  3WCJ A;  5DIQ F;  5B0M A;  5JV1 F;  3SDV A;  4LFG A;  3ICM A;  3N45 F;  2Z4Y A;  3WSB A;  1VG4 A;  1WKZ A;  4QPF A;  4OKM A;  4KKM A;  3AQB B;  1RQI A;  3KRF A;  5JA0 F;  5IN8 A;  5ERM A;  1YYS A;  3AQ0 A;  4JXN A;  3ACW A;  1EZF A;  5A0J A;  5B00 A;  1ZW5 A;  2AET A;  1YHK A;  3KRO A;  5IMI A;  4DI5 A;  5KSX F;  4NFJ F;  3WJO A;  5A0K A;  3N5J F;  3TS7 A;  3KRC A;  3PYB A;  3VJ8 A;  3RMG A;  3RYE A;  2ZEV A;  2AZJ A;  4GP1 A;  5DHK A;  1JFG A;  4NFK F;  2PS5 A;  1VG3 A;  3Q30 A;  3OYR A;  3ADZ A;  1YHL A;  2E8T A;  2Q80 A;  3WCG A;  1YYQ A;  4DWG A;  1UBX A;  2E90 A;  4N9U A;  2E4O A;  2I19 A;  1PS1 A;  4KUX A;  4DXJ A;  2RAH A;  2Q9Y A;  3CC9 A;  4RXA A;  3QQV A;  4LA5 A;  3ICK A;  2E8V A;  4XQT F;  5IK6 A;  3P41 A;  1UBY A;  4KVY A;  1WL0 A;  4K10 A;  1HM7 A;  1YHM A;  4KPJ A;  2AEK A;  3SDQ A;  5E8L A;  2QIS A;  1HXG A;  3EGT A;  4DEM F;  3PH7 A;  3MZV A;  3S4J A;  4F6X A;  3N0F A;  5H9D A;  1HX9 A;  1WL3 A;  1YYU A;  5AHU B;  3WEG A;  4LA6 A;  4LUU A;  4EA0 A;  3VJD A;  3WSA A;  4PVY F;  3LGZ B;  1FPS A;  4L2X F;  3W7F A;  3VJA A;  5JV2 F;  4LPG F;  3RYW A;  2AZL A;  3WEK A;  4KQU A;  4NUA A;  3AQC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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