3N46F

Human fpps complex with nov_980 and zoledronic acid/mg2+
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE
total genus 132
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2010-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3n46F00
2E95A 1VG7A 4LFGA 1JFAA 5DJRF 1RQIA 3VJBA 3VJCA 3M0GA 2E92A 4F62A 3MAVA 3Q2ZA 3ICZA 1RTRA 5E8HA 3KB9A 4NFKF 1YYRA 4LZ0A 3SAEA 4ZQ8A 3ZL6A 3ID0A 5IKHA 2Z7IA 4MC0A 4GA3A 2AETA 2F89F 3OACA 2VF6A 5KSXF 4JVJF 4NG6A 3KRAB 3WCJA 3ZMBA 1YV5A 5AFXA 3P5PA 2PS6A 5JA0F 5C05A 5B01A 4NFJF 3Q1OA 2F92F 2Z4VA 5DGMF 4JZBA 5ILHA 3N0GA 5B03A 2E8UA 5B0MA 3WEHA 1WY0A 4NUAA 5ILZA 4NKEA 1KIZA 3PH7A 1HXCA 4KWDA 3AQ0A 1WL1A 5DJPF 4KPDA 5ILKA 1WL3A 3LLWA 3WEIA 2I19A 1N21A 3NRIA 3VJ8A 4E1EA 2RAHA 2J1OA 3V66A 1YYTA 5JV1F 1YHKA 2OGDA 3OABB 3OACB 2PS8A 3AQBB 3LEEA 4KUXA 1UBVA 3WCLA 4XQRF 1HM7A 2F8CF 3APZA 3N6KF 3M01A 4KFAA 1V4HA 3PYAA 1YHLA 5EAUA 5ERNA 3DYFA 1N1ZA 2AZLA 3WCMA 5CG5A 3N0FA 3WEJA 5DHIA 2ZY1A 3CP6A 4LPHF 1YYSA 4UMJA 4E9ZA 3ADZA 5IK0A 2OA6A 1HX9A 3EZ3A 3N5HF 4P0WA 3WCIA 3RBMA 1N24A 4FP4A 5JV2F 3OYRA 3SDTA 4RXDA 4N9UA 2ZCSA 5DJVF 4KVDA 2E8TA 3N45F 3WEFA 5HN9A 4QPFA 4KK2A 4PVXF 3RYWA 2ZEUA 3QQVA 2F8ZF 3LJIA 4EA1A 3WEKA 2P1CA 3S4JA 3QKCA 4EA2A 3S9VA 2E4OA 3KROA 4MC3A 3DYGA 3KRFB 1DI1A 3Q2QA 4KPJA 2E93A 2AZKA 3NPKA 1KIYA 3WCBA 3M00A 4LZ3A 3WCDA 1YHMA 2FORA 4RXEA 3KRCA 5IMNA 5I1UA 3ACWA 4LFEA 3M02A 5B0IA 2Z4WA 4OKZA 3V1XA 3G4FA 3WCGA 3KRPA 3P8LA 4GAXA 3N1WF 4DWGA 3NPRA 1WMWA 2ZCRA 5ERMA 2E90A 1UBWA 2ONHA 2F94F 4MC8A 2Q58A 5DHKA 5ER8A 5IMPA 2Q9ZA 4KVIA 4LTVA 5EATA 3V1VA 1N23A 3LVSA 4LLSA 1RQJA 5JV0F 3AE0A 2E94A 4JXNA 3EFQA 1HXAA 3ASXA 2AZJA 2ZEVA 2ZCOA 3WCEA 5B0KA 4OGUA 1ZW5A 1WL2A 3TC1A 4K10A 5IK6A 3ICKA 4DWBA 5B0LA 4JXYA 3WSBA 1VG3A 5ILIA 3CC9A 1N22A 3M9UA 4FJQA 3Q30A 3WJNA 3LGKA 3VJDA 1V4IA 3EGTA 3WCHA 1EZFA 4OMGA 5AHUB 4P0VA 3B7LA 3WJOA 2ZCQA 4KVYA 5HNAA 2DH4A 3BNYA 4LPGF 5A0IA 3ZMCA 3LMDA 5B0JA 3WEGA 4LLTA 3W7FA 3N46F 2J1PA 3P5RA 5E8LA 3LZ9A 2PS5A 4DZWA 2F7MF 2OPNA 3N3LF 5IMIA 4H5CF 3ACYA 4GP1A 3P41A 1VG6A 3TFNA 2QISA 3VJAA 4XQTF 1UBXA 5ILDA 3SDUA 5AYPA 1WL0A 2PS7A 5A0KA 1HXGA 4KVWA 1YQ7A 1V4JA 1WKZA 4LTZA 4F6VA 3BNXA 3IPIA 4RNQA 5DIQF 3SDQA 3ZOUA 5IL3A 4GP2A 3KRAA 4Q23A 4KQ5A 3WJKA 2E8VA 5B00A 3LOMA 4LFVF 3ICNA 4NKFA 3ICMA 3KBKA 4EA0A 3N49F 3PKOA 4LUUA 4QXSF 3ZCDA 3G4DA 3PYBA 5DGNF 3P8RA 4H5DF 3CKEA 3WCAA 5HN8A 2EWGA 4F6XA 5IL8A 4DHDA 1V4KA 1UBYA 3N1VF 3PDEA 5IM1A 5H9DA 2Z78A 3WCCA 1VG4A 3KROB 5JUZF 2F9KF 3LGZB 3N3DA 5IKAA 3OABA 1V4EA 3N5JF 4KQSA 3KRCB 2FTZA 2Z7HA 2OPMA 4LIXA 2O1OA 3UCAA 1DGPA 3TFVA 3KRPB 2AEKA 2J5CA 3LK5A 3WE9A 1JFGA 5A0JA 3LDWA 1N20A 4RXAA 3VJEA 5ILYA 4WK5A 3SDRA 4LA6A 3MZVA 3WCFA 1N1BA 1HM4A 1YYUA 1PS1A 3TS7A 3ACXA 5IVGA 5EROA 3LSNA 1FPSA 4OMHA 4RXCA 3DYHA 3WC9A 4JZXA 4XQSF 3NF2A 4RYPA 2AELA 4KQUA 4OKMA 5IK9A 5HN7A 3KRFA 4N1ZF 5E8KA 2E8WA 3RMGA 3TFPA 4KKMA 4LZCA 5IN8A 2Q9YA 3RYEA 4LA5A 1VG2A 4H5EF 2Z4XA 2E91A 2E8XA 2PS4A 5ILJA 2Z50A 4LXWA 4PVYF 3LG5A 4DXJA 5DZ2A 2Q80A 5CG6A 2Z4ZA 2H8OA 2Z4YA 5B02A 4L2XF 4DI5A 3IBAA 3SDVA 5DW7A 2Z52A 4E9UA 3AQCB 3WSAA 4DEMF 4P0XA 4JYXA 3VJ9A 5DGSF 4LOBA 1YYQA 5EASA 1YJ4A 4NFIF 2ONGA 4HD1A 5AELA
chains in the Genus database with same CATH superfamily
2E95A 1VG7A 4LFGA 1JFAA 5DJRF 1RQIA 3VJBA 3VJCA 3M0GA 2E92A 4F62A 3MAVA 3Q2ZA 3ICZA 1RTRA 5E8HA 3KB9A 4NFKF 1YYRA 4LZ0A 3SAEA 4ZQ8A 3ZL6A 3ID0A 5IKHA 2Z7IA 4MC0A 4GA3A 2AETA 2F89F 3OACA 2VF6A 5KSXF 4JVJF 4NG6A 3KRAB 3WCJA 3ZMBA 1YV5A 5AFXA 3P5PA 2PS6A 5JA0F 5C05A 5B01A 4NFJF 3Q1OA 2F92F 2Z4VA 5DGMF 4JZBA 5ILHA 3N0GA 5B03A 2E8UA 5B0MA 3WEHA 1WY0A 4NUAA 5ILZA 4NKEA 1KIZA 3PH7A 1HXCA 4KWDA 3AQ0A 1WL1A 5DJPF 4KPDA 5ILKA 1WL3A 3LLWA 3WEIA 2I19A 1N21A 3NRIA 3VJ8A 4E1EA 2RAHA 2J1OA 3V66A 1YYTA 5JV1F 1YHKA 2OGDA 3OABB 3OACB 2PS8A 3AQBB 3LEEA 4KUXA 1UBVA 3WCLA 4XQRF 1HM7A 2F8CF 3APZA 3N6KF 3M01A 4KFAA 1V4HA 3PYAA 1YHLA 5EAUA 5ERNA 3DYFA 1N1ZA 2AZLA 3WCMA 5CG5A 3N0FA 3WEJA 5DHIA 2ZY1A 3CP6A 4LPHF 1YYSA 4UMJA 4E9ZA 3ADZA 5IK0A 2OA6A 1HX9A 3EZ3A 3N5HF 4P0WA 3WCIA 3RBMA 1N24A 4FP4A 5JV2F 3OYRA 3SDTA 4RXDA 4N9UA 2ZCSA 5DJVF 4KVDA 2E8TA 3N45F 3WEFA 5HN9A 4QPFA 4KK2A 4PVXF 3RYWA 2ZEUA 3QQVA 2F8ZF 3LJIA 4EA1A 3WEKA 2P1CA 3S4JA 3QKCA 4EA2A 3S9VA 2E4OA 3KROA 4MC3A 3DYGA 3KRFB 1DI1A 3Q2QA 4KPJA 2E93A 2AZKA 3NPKA 1KIYA 3WCBA 3M00A 4LZ3A 3WCDA 1YHMA 2FORA 4RXEA 3KRCA 5IMNA 5I1UA 3ACWA 4LFEA 3M02A 5B0IA 2Z4WA 4OKZA 3V1XA 3G4FA 3WCGA 3KRPA 3P8LA 4GAXA 3N1WF 4DWGA 3NPRA 1WMWA 2ZCRA 5ERMA 2E90A 1UBWA 2ONHA 2F94F 4MC8A 2Q58A 5DHKA 5ER8A 5IMPA 2Q9ZA 4KVIA 4LTVA 5EATA 3V1VA 1N23A 3LVSA 4LLSA 1RQJA 5JV0F 3AE0A 2E94A 4JXNA 3EFQA 1HXAA 3ASXA 2AZJA 2ZEVA 2ZCOA 3WCEA 5B0KA 4OGUA 1ZW5A 1WL2A 3TC1A 4K10A 5IK6A 3ICKA 4DWBA 5B0LA 4JXYA 3WSBA 1VG3A 5ILIA 3CC9A 1N22A 3M9UA 4FJQA 3Q30A 3WJNA 3LGKA 3VJDA 1V4IA 3EGTA 3WCHA 1EZFA 4OMGA 5AHUB 4P0VA 3B7LA 3WJOA 2ZCQA 4KVYA 5HNAA 2DH4A 3BNYA 4LPGF 5A0IA 3ZMCA 3LMDA 5B0JA 3WEGA 4LLTA 3W7FA 3N46F 2J1PA 3P5RA 5E8LA 3LZ9A 2PS5A 4DZWA 2F7MF 2OPNA 3N3LF 5IMIA 4H5CF 3ACYA 4GP1A 3P41A 1VG6A 3TFNA 2QISA 3VJAA 4XQTF 1UBXA 5ILDA 3SDUA 5AYPA 1WL0A 2PS7A 5A0KA 1HXGA 4KVWA 1YQ7A 1V4JA 1WKZA 4LTZA 4F6VA 3BNXA 3IPIA 4RNQA 5DIQF 3SDQA 3ZOUA 5IL3A 4GP2A 3KRAA 4Q23A 4KQ5A 3WJKA 2E8VA 5B00A 3LOMA 4LFVF 3ICNA 4NKFA 3ICMA 3KBKA 4EA0A 3N49F 3PKOA 4LUUA 4QXSF 3ZCDA 3G4DA 3PYBA 5DGNF 3P8RA 4H5DF 3CKEA 3WCAA 5HN8A 2EWGA 4F6XA 5IL8A 4DHDA 1V4KA 1UBYA 3N1VF 3PDEA 5IM1A 5H9DA 2Z78A 3WCCA 1VG4A 3KROB 5JUZF 2F9KF 3LGZB 3N3DA 5IKAA 3OABA 1V4EA 3N5JF 4KQSA 3KRCB 2FTZA 2Z7HA 2OPMA 4LIXA 2O1OA 3UCAA 1DGPA 3TFVA 3KRPB 2AEKA 2J5CA 3LK5A 3WE9A 1JFGA 5A0JA 3LDWA 1N20A 4RXAA 3VJEA 5ILYA 4WK5A 3SDRA 4LA6A 3MZVA 3WCFA 1N1BA 1HM4A 1YYUA 1PS1A 3TS7A 3ACXA 5IVGA 5EROA 3LSNA 1FPSA 4OMHA 4RXCA 3DYHA 3WC9A 4JZXA 4XQSF 3NF2A 4RYPA 2AELA 4KQUA 4OKMA 5IK9A 5HN7A 3KRFA 4N1ZF 5E8KA 2E8WA 3RMGA 3TFPA 4KKMA 4LZCA 5IN8A 2Q9YA 3RYEA 4LA5A 1VG2A 4H5EF 2Z4XA 2E91A 2E8XA 2PS4A 5ILJA 2Z50A 4LXWA 4PVYF 3LG5A 4DXJA 5DZ2A 2Q80A 5CG6A 2Z4ZA 2H8OA 2Z4YA 5B02A 4L2XF 4DI5A 3IBAA 3SDVA 5DW7A 2Z52A 4E9UA 3AQCB 3WSAA 4DEMF 4P0XA 4JYXA 3VJ9A 5DGSF 4LOBA 1YYQA 5EASA 1YJ4A 4NFIF 2ONGA 4HD1A 5AELA
chains in the Genus database with same CATH topology
2E95A 1VG7A 4LFGA 1JFAA 5DJRF 1RQIA 3VJBA 3VJCA 3M0GA 2E92A 4F62A 3MAVA 3Q2ZA 3ICZA 1RTRA 5E8HA 3KB9A 4NFKF 1YYRA 4LZ0A 3SAEA 4ZQ8A 3ZL6A 3ID0A 5IKHA 2Z7IA 4MC0A 4GA3A 2AETA 2F89F 3OACA 2VF6A 5KSXF 4JVJF 4NG6A 3KRAB 3WCJA 3ZMBA 1YV5A 5AFXA 3P5PA 2PS6A 5JA0F 5C05A 5B01A 4NFJF 3Q1OA 2F92F 2Z4VA 5DGMF 4JZBA 5ILHA 3N0GA 5B03A 2E8UA 5B0MA 3WEHA 1WY0A 4NUAA 5ILZA 4NKEA 1KIZA 3PH7A 1HXCA 4KWDA 3AQ0A 1WL1A 5DJPF 4KPDA 5ILKA 1WL3A 3LLWA 3WEIA 2I19A 1N21A 3NRIA 3VJ8A 4E1EA 2RAHA 2J1OA 3V66A 1YYTA 5JV1F 1YHKA 2OGDA 3OABB 3OACB 2PS8A 3AQBB 3LEEA 4KUXA 1UBVA 3WCLA 4XQRF 1HM7A 2F8CF 3APZA 3N6KF 3M01A 4KFAA 1V4HA 3PYAA 1YHLA 5EAUA 5ERNA 3DYFA 1N1ZA 2AZLA 3WCMA 5CG5A 3N0FA 3WEJA 5DHIA 2ZY1A 3CP6A 4LPHF 1YYSA 4UMJA 4E9ZA 3ADZA 5IK0A 2OA6A 1HX9A 3EZ3A 3N5HF 4P0WA 3WCIA 3RBMA 1N24A 4FP4A 5JV2F 3OYRA 3SDTA 4RXDA 4N9UA 2ZCSA 5DJVF 4KVDA 2E8TA 3N45F 3WEFA 5HN9A 4QPFA 4KK2A 4PVXF 3RYWA 2ZEUA 3QQVA 2F8ZF 3LJIA 4EA1A 3WEKA 2P1CA 3S4JA 3QKCA 4EA2A 3S9VA 2E4OA 3KROA 4MC3A 3DYGA 3KRFB 1DI1A 3Q2QA 4KPJA 2E93A 2AZKA 3NPKA 1KIYA 3WCBA 3M00A 4LZ3A 3WCDA 1YHMA 2FORA 4RXEA 3KRCA 5IMNA 5I1UA 3ACWA 4LFEA 3M02A 5B0IA 2Z4WA 4OKZA 3V1XA 3G4FA 3WCGA 3KRPA 3P8LA 4GAXA 3N1WF 4DWGA 3NPRA 1WMWA 2ZCRA 5ERMA 2E90A 1UBWA 2ONHA 2F94F 4MC8A 2Q58A 5DHKA 5ER8A 5IMPA 2Q9ZA 4KVIA 4LTVA 5EATA 3V1VA 1N23A 3LVSA 4LLSA 1RQJA 5JV0F 3AE0A 2E94A 4JXNA 3EFQA 1HXAA 3ASXA 2AZJA 2ZEVA 2ZCOA 3WCEA 5B0KA 4OGUA 1ZW5A 1WL2A 3TC1A 4K10A 5IK6A 3ICKA 4DWBA 5B0LA 4JXYA 3WSBA 1VG3A 5ILIA 3CC9A 1N22A 3M9UA 4FJQA 3Q30A 3WJNA 3LGKA 3VJDA 1V4IA 3EGTA 3WCHA 1EZFA 4OMGA 5AHUB 4P0VA 3B7LA 3WJOA 2ZCQA 4KVYA 5HNAA 2DH4A 3BNYA 4LPGF 5A0IA 3ZMCA 3LMDA 5B0JA 3WEGA 4LLTA 3W7FA 3N46F 2J1PA 3P5RA 5E8LA 3LZ9A 2PS5A 4DZWA 2F7MF 2OPNA 3N3LF 5IMIA 4H5CF 3ACYA 4GP1A 3P41A 1VG6A 3TFNA 2QISA 3VJAA 4XQTF 1UBXA 5ILDA 3SDUA 5AYPA 1WL0A 2PS7A 5A0KA 1HXGA 4KVWA 1YQ7A 1V4JA 1WKZA 4LTZA 4F6VA 3BNXA 3IPIA 4RNQA 5DIQF 3SDQA 3ZOUA 5IL3A 4GP2A 3KRAA 4Q23A 4KQ5A 3WJKA 2E8VA 5B00A 3LOMA 4LFVF 3ICNA 4NKFA 3ICMA 3KBKA 4EA0A 3N49F 3PKOA 4LUUA 4QXSF 3ZCDA 3G4DA 3PYBA 5DGNF 3P8RA 4H5DF 3CKEA 3WCAA 5HN8A 2EWGA 4F6XA 5IL8A 4DHDA 1V4KA 1UBYA 3N1VF 3PDEA 5IM1A 5H9DA 2Z78A 3WCCA 1VG4A 3KROB 5JUZF 2F9KF 3LGZB 3N3DA 5IKAA 3OABA 1V4EA 3N5JF 4KQSA 3KRCB 2FTZA 2Z7HA 2OPMA 4LIXA 2O1OA 3UCAA 1DGPA 3TFVA 3KRPB 2AEKA 2J5CA 3LK5A 3WE9A 1JFGA 5A0JA 3LDWA 1N20A 4RXAA 3VJEA 5ILYA 4WK5A 3SDRA 4LA6A 3MZVA 3WCFA 1N1BA 1HM4A 1YYUA 1PS1A 3TS7A 3ACXA 5IVGA 5EROA 3LSNA 1FPSA 4OMHA 4RXCA 3DYHA 3WC9A 4JZXA 4XQSF 3NF2A 4RYPA 2AELA 4KQUA 4OKMA 5IK9A 5HN7A 3KRFA 4N1ZF 5E8KA 2E8WA 3RMGA 3TFPA 4KKMA 4LZCA 5IN8A 2Q9YA 3RYEA 4LA5A 1VG2A 4H5EF 2Z4XA 2E91A 2E8XA 2PS4A 5ILJA 2Z50A 4LXWA 4PVYF 3LG5A 4DXJA 5DZ2A 2Q80A 5CG6A 2Z4ZA 2H8OA 2Z4YA 5B02A 4L2XF 4DI5A 3IBAA 3SDVA 5DW7A 2Z52A 4E9UA 3AQCB 3WSAA 4DEMF 4P0XA 4JYXA 3VJ9A 5DGSF 4LOBA 1YYQA 5EASA 1YJ4A 4NFIF 2ONGA 4HD1A 5AELA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2E95 A;  1VG7 A;  4LFG A;  1JFA A;  5DJR F;  1RQI A;  3VJB A;  3VJC A;  3M0G A;  2E92 A;  4F62 A;  3MAV A;  3Q2Z A;  3ICZ A;  1RTR A;  5E8H A;  3KB9 A;  4NFK F;  1YYR A;  4LZ0 A;  3SAE A;  4ZQ8 A;  3ZL6 A;  3ID0 A;  5IKH A;  2Z7I A;  4MC0 A;  4GA3 A;  2AET A;  2F89 F;  3OAC A;  2VF6 A;  5KSX F;  4JVJ F;  4NG6 A;  3KRA B;  3WCJ A;  3ZMB A;  1YV5 A;  5AFX A;  3P5P A;  2PS6 A;  5JA0 F;  5C05 A;  5B01 A;  4NFJ F;  3Q1O A;  2F92 F;  2Z4V A;  5DGM F;  4JZB A;  5ILH A;  3N0G A;  5B03 A;  2E8U A;  5B0M A;  3WEH A;  1WY0 A;  4NUA A;  5ILZ A;  4NKE A;  1KIZ A;  3PH7 A;  1HXC A;  4KWD A;  3AQ0 A;  1WL1 A;  5DJP F;  4KPD A;  5ILK A;  1WL3 A;  3LLW A;  3WEI A;  2I19 A;  1N21 A;  3NRI A;  3VJ8 A;  4E1E A;  2RAH A;  2J1O A;  3V66 A;  1YYT A;  5JV1 F;  1YHK A;  2OGD A;  3OAB B;  3OAC B;  2PS8 A;  3AQB B;  3LEE A;  4KUX A;  1UBV A;  3WCL A;  4XQR F;  1HM7 A;  2F8C F;  3APZ A;  3N6K F;  3M01 A;  4KFA A;  1V4H A;  3PYA A;  1YHL A;  5EAU A;  5ERN A;  3DYF A;  1N1Z A;  2AZL A;  3WCM A;  5CG5 A;  3N0F A;  3WEJ A;  5DHI A;  2ZY1 A;  3CP6 A;  4LPH F;  1YYS A;  4UMJ A;  4E9Z A;  3ADZ A;  5IK0 A;  2OA6 A;  1HX9 A;  3EZ3 A;  3N5H F;  4P0W A;  3WCI A;  3RBM A;  1N24 A;  4FP4 A;  5JV2 F;  3OYR A;  3SDT A;  4RXD A;  4N9U A;  2ZCS A;  5DJV F;  4KVD A;  2E8T A;  3N45 F;  3WEF A;  5HN9 A;  4QPF A;  4KK2 A;  4PVX F;  3RYW A;  2ZEU A;  3QQV A;  2F8Z F;  3LJI A;  4EA1 A;  3WEK A;  2P1C A;  3S4J A;  3QKC A;  4EA2 A;  3S9V A;  2E4O A;  3KRO A;  4MC3 A;  3DYG A;  3KRF B;  1DI1 A;  3Q2Q A;  4KPJ A;  2E93 A;  2AZK A;  3NPK A;  1KIY A;  3WCB A;  3M00 A;  4LZ3 A;  3WCD A;  1YHM A;  2FOR A;  4RXE A;  3KRC A;  5IMN A;  5I1U A;  3ACW A;  4LFE A;  3M02 A;  5B0I A;  2Z4W A;  4OKZ A;  3V1X A;  3G4F A;  3WCG A;  3KRP A;  3P8L A;  4GAX A;  3N1W F;  4DWG A;  3NPR A;  1WMW A;  2ZCR A;  5ERM A;  2E90 A;  1UBW A;  2ONH A;  2F94 F;  4MC8 A;  2Q58 A;  5DHK A;  5ER8 A;  5IMP A;  2Q9Z A;  4KVI A;  4LTV A;  5EAT A;  3V1V A;  1N23 A;  3LVS A;  4LLS A;  1RQJ A;  5JV0 F;  3AE0 A;  2E94 A;  4JXN A;  3EFQ A;  1HXA A;  3ASX A;  2AZJ A;  2ZEV A;  2ZCO A;  3WCE A;  5B0K A;  4OGU A;  1ZW5 A;  1WL2 A;  3TC1 A;  4K10 A;  5IK6 A;  3ICK A;  4DWB A;  5B0L A;  4JXY A;  3WSB A;  1VG3 A;  5ILI A;  3CC9 A;  1N22 A;  3M9U A;  4FJQ A;  3Q30 A;  3WJN A;  3LGK A;  3VJD A;  1V4I A;  3EGT A;  3WCH A;  1EZF A;  4OMG A;  5AHU B;  4P0V A;  3B7L A;  3WJO A;  2ZCQ A;  4KVY A;  5HNA A;  2DH4 A;  3BNY A;  4LPG F;  5A0I A;  3ZMC A;  3LMD A;  5B0J A;  3WEG A;  4LLT A;  3W7F A;  3N46 F;  2J1P A;  3P5R A;  5E8L A;  3LZ9 A;  2PS5 A;  4DZW A;  2F7M F;  2OPN A;  3N3L F;  5IMI A;  4H5C F;  3ACY A;  4GP1 A;  3P41 A;  1VG6 A;  3TFN A;  2QIS A;  3VJA A;  4XQT F;  1UBX A;  5ILD A;  3SDU A;  5AYP A;  1WL0 A;  2PS7 A;  5A0K A;  1HXG A;  4KVW A;  1YQ7 A;  1V4J A;  1WKZ A;  4LTZ A;  4F6V A;  3BNX A;  3IPI A;  4RNQ A;  5DIQ F;  3SDQ A;  3ZOU A;  5IL3 A;  4GP2 A;  3KRA A;  4Q23 A;  4KQ5 A;  3WJK A;  2E8V A;  5B00 A;  3LOM A;  4LFV F;  3ICN A;  4NKF A;  3ICM A;  3KBK A;  4EA0 A;  3N49 F;  3PKO A;  4LUU A;  4QXS F;  3ZCD A;  3G4D A;  3PYB A;  5DGN F;  3P8R A;  4H5D F;  3CKE A;  3WCA A;  5HN8 A;  2EWG A;  4F6X A;  5IL8 A;  4DHD A;  1V4K A;  1UBY A;  3N1V F;  3PDE A;  5IM1 A;  5H9D A;  2Z78 A;  3WCC A;  1VG4 A;  3KRO B;  5JUZ F;  2F9K F;  3LGZ B;  3N3D A;  5IKA A;  3OAB A;  1V4E A;  3N5J F;  4KQS A;  3KRC B;  2FTZ A;  2Z7H A;  2OPM A;  4LIX A;  2O1O A;  3UCA A;  1DGP A;  3TFV A;  3KRP B;  2AEK A;  2J5C A;  3LK5 A;  3WE9 A;  1JFG A;  5A0J A;  3LDW A;  1N20 A;  4RXA A;  3VJE A;  5ILY A;  4WK5 A;  3SDR A;  4LA6 A;  3MZV A;  3WCF A;  1N1B A;  1HM4 A;  1YYU A;  1PS1 A;  3TS7 A;  3ACX A;  5IVG A;  5ERO A;  3LSN A;  1FPS A;  4OMH A;  4RXC A;  3DYH A;  3WC9 A;  4JZX A;  4XQS F;  3NF2 A;  4RYP A;  2AEL A;  4KQU A;  4OKM A;  5IK9 A;  5HN7 A;  3KRF A;  4N1Z F;  5E8K A;  2E8W A;  3RMG A;  3TFP A;  4KKM A;  4LZC A;  5IN8 A;  2Q9Y A;  3RYE A;  4LA5 A;  1VG2 A;  4H5E F;  2Z4X A;  2E91 A;  2E8X A;  2PS4 A;  5ILJ A;  2Z50 A;  4LXW A;  4PVY F;  3LG5 A;  4DXJ A;  5DZ2 A;  2Q80 A;  5CG6 A;  2Z4Z A;  2H8O A;  2Z4Y A;  5B02 A;  4L2X F;  4DI5 A;  3IBA A;  3SDV A;  5DW7 A;  2Z52 A;  4E9U A;  3AQC B;  3WSA A;  4DEM F;  4P0X A;  4JYX A;  3VJ9 A;  5DGS F;  4LOB A;  1YYQ A;  5EAS A;  1YJ4 A;  4NFI F;  2ONG A;  4HD1 A;  5AEL A; 
#chains in the Genus database with same CATH topology
 2E95 A;  1VG7 A;  4LFG A;  1JFA A;  5DJR F;  1RQI A;  3VJB A;  3VJC A;  3M0G A;  2E92 A;  4F62 A;  3MAV A;  3Q2Z A;  3ICZ A;  1RTR A;  5E8H A;  3KB9 A;  4NFK F;  1YYR A;  4LZ0 A;  3SAE A;  4ZQ8 A;  3ZL6 A;  3ID0 A;  5IKH A;  2Z7I A;  4MC0 A;  4GA3 A;  2AET A;  2F89 F;  3OAC A;  2VF6 A;  5KSX F;  4JVJ F;  4NG6 A;  3KRA B;  3WCJ A;  3ZMB A;  1YV5 A;  5AFX A;  3P5P A;  2PS6 A;  5JA0 F;  5C05 A;  5B01 A;  4NFJ F;  3Q1O A;  2F92 F;  2Z4V A;  5DGM F;  4JZB A;  5ILH A;  3N0G A;  5B03 A;  2E8U A;  5B0M A;  3WEH A;  1WY0 A;  4NUA A;  5ILZ A;  4NKE A;  1KIZ A;  3PH7 A;  1HXC A;  4KWD A;  3AQ0 A;  1WL1 A;  5DJP F;  4KPD A;  5ILK A;  1WL3 A;  3LLW A;  3WEI A;  2I19 A;  1N21 A;  3NRI A;  3VJ8 A;  4E1E A;  2RAH A;  2J1O A;  3V66 A;  1YYT A;  5JV1 F;  1YHK A;  2OGD A;  3OAB B;  3OAC B;  2PS8 A;  3AQB B;  3LEE A;  4KUX A;  1UBV A;  3WCL A;  4XQR F;  1HM7 A;  2F8C F;  3APZ A;  3N6K F;  3M01 A;  4KFA A;  1V4H A;  3PYA A;  1YHL A;  5EAU A;  5ERN A;  3DYF A;  1N1Z A;  2AZL A;  3WCM A;  5CG5 A;  3N0F A;  3WEJ A;  5DHI A;  2ZY1 A;  3CP6 A;  4LPH F;  1YYS A;  4UMJ A;  4E9Z A;  3ADZ A;  5IK0 A;  2OA6 A;  1HX9 A;  3EZ3 A;  3N5H F;  4P0W A;  3WCI A;  3RBM A;  1N24 A;  4FP4 A;  5JV2 F;  3OYR A;  3SDT A;  4RXD A;  4N9U A;  2ZCS A;  5DJV F;  4KVD A;  2E8T A;  3N45 F;  3WEF A;  5HN9 A;  4QPF A;  4KK2 A;  4PVX F;  3RYW A;  2ZEU A;  3QQV A;  2F8Z F;  3LJI A;  4EA1 A;  3WEK A;  2P1C A;  3S4J A;  3QKC A;  4EA2 A;  3S9V A;  2E4O A;  3KRO A;  4MC3 A;  3DYG A;  3KRF B;  1DI1 A;  3Q2Q A;  4KPJ A;  2E93 A;  2AZK A;  3NPK A;  1KIY A;  3WCB A;  3M00 A;  4LZ3 A;  3WCD A;  1YHM A;  2FOR A;  4RXE A;  3KRC A;  5IMN A;  5I1U A;  3ACW A;  4LFE A;  3M02 A;  5B0I A;  2Z4W A;  4OKZ A;  3V1X A;  3G4F A;  3WCG A;  3KRP A;  3P8L A;  4GAX A;  3N1W F;  4DWG A;  3NPR A;  1WMW A;  2ZCR A;  5ERM A;  2E90 A;  1UBW A;  2ONH A;  2F94 F;  4MC8 A;  2Q58 A;  5DHK A;  5ER8 A;  5IMP A;  2Q9Z A;  4KVI A;  4LTV A;  5EAT A;  3V1V A;  1N23 A;  3LVS A;  4LLS A;  1RQJ A;  5JV0 F;  3AE0 A;  2E94 A;  4JXN A;  3EFQ A;  1HXA A;  3ASX A;  2AZJ A;  2ZEV A;  2ZCO A;  3WCE A;  5B0K A;  4OGU A;  1ZW5 A;  1WL2 A;  3TC1 A;  4K10 A;  5IK6 A;  3ICK A;  4DWB A;  5B0L A;  4JXY A;  3WSB A;  1VG3 A;  5ILI A;  3CC9 A;  1N22 A;  3M9U A;  4FJQ A;  3Q30 A;  3WJN A;  3LGK A;  3VJD A;  1V4I A;  3EGT A;  3WCH A;  1EZF A;  4OMG A;  5AHU B;  4P0V A;  3B7L A;  3WJO A;  2ZCQ A;  4KVY A;  5HNA A;  2DH4 A;  3BNY A;  4LPG F;  5A0I A;  3ZMC A;  3LMD A;  5B0J A;  3WEG A;  4LLT A;  3W7F A;  3N46 F;  2J1P A;  3P5R A;  5E8L A;  3LZ9 A;  2PS5 A;  4DZW A;  2F7M F;  2OPN A;  3N3L F;  5IMI A;  4H5C F;  3ACY A;  4GP1 A;  3P41 A;  1VG6 A;  3TFN A;  2QIS A;  3VJA A;  4XQT F;  1UBX A;  5ILD A;  3SDU A;  5AYP A;  1WL0 A;  2PS7 A;  5A0K A;  1HXG A;  4KVW A;  1YQ7 A;  1V4J A;  1WKZ A;  4LTZ A;  4F6V A;  3BNX A;  3IPI A;  4RNQ A;  5DIQ F;  3SDQ A;  3ZOU A;  5IL3 A;  4GP2 A;  3KRA A;  4Q23 A;  4KQ5 A;  3WJK A;  2E8V A;  5B00 A;  3LOM A;  4LFV F;  3ICN A;  4NKF A;  3ICM A;  3KBK A;  4EA0 A;  3N49 F;  3PKO A;  4LUU A;  4QXS F;  3ZCD A;  3G4D A;  3PYB A;  5DGN F;  3P8R A;  4H5D F;  3CKE A;  3WCA A;  5HN8 A;  2EWG A;  4F6X A;  5IL8 A;  4DHD A;  1V4K A;  1UBY A;  3N1V F;  3PDE A;  5IM1 A;  5H9D A;  2Z78 A;  3WCC A;  1VG4 A;  3KRO B;  5JUZ F;  2F9K F;  3LGZ B;  3N3D A;  5IKA A;  3OAB A;  1V4E A;  3N5J F;  4KQS A;  3KRC B;  2FTZ A;  2Z7H A;  2OPM A;  4LIX A;  2O1O A;  3UCA A;  1DGP A;  3TFV A;  3KRP B;  2AEK A;  2J5C A;  3LK5 A;  3WE9 A;  1JFG A;  5A0J A;  3LDW A;  1N20 A;  4RXA A;  3VJE A;  5ILY A;  4WK5 A;  3SDR A;  4LA6 A;  3MZV A;  3WCF A;  1N1B A;  1HM4 A;  1YYU A;  1PS1 A;  3TS7 A;  3ACX A;  5IVG A;  5ERO A;  3LSN A;  1FPS A;  4OMH A;  4RXC A;  3DYH A;  3WC9 A;  4JZX A;  4XQS F;  3NF2 A;  4RYP A;  2AEL A;  4KQU A;  4OKM A;  5IK9 A;  5HN7 A;  3KRF A;  4N1Z F;  5E8K A;  2E8W A;  3RMG A;  3TFP A;  4KKM A;  4LZC A;  5IN8 A;  2Q9Y A;  3RYE A;  4LA5 A;  1VG2 A;  4H5E F;  2Z4X A;  2E91 A;  2E8X A;  2PS4 A;  5ILJ A;  2Z50 A;  4LXW A;  4PVY F;  3LG5 A;  4DXJ A;  5DZ2 A;  2Q80 A;  5CG6 A;  2Z4Z A;  2H8O A;  2Z4Y A;  5B02 A;  4L2X F;  4DI5 A;  3IBA A;  3SDV A;  5DW7 A;  2Z52 A;  4E9U A;  3AQC B;  3WSA A;  4DEM F;  4P0X A;  4JYX A;  3VJ9 A;  5DGS F;  4LOB A;  1YYQ A;  5EAS A;  1YJ4 A;  4NFI F;  2ONG A;  4HD1 A;  5AEL A; 
#chains in the Genus database with same CATH homology
 2E95 A;  1VG7 A;  4LFG A;  1JFA A;  5DJR F;  1RQI A;  3VJB A;  3VJC A;  3M0G A;  2E92 A;  4F62 A;  3MAV A;  3Q2Z A;  3ICZ A;  1RTR A;  5E8H A;  3KB9 A;  4NFK F;  1YYR A;  4LZ0 A;  3SAE A;  4ZQ8 A;  3ZL6 A;  3ID0 A;  5IKH A;  2Z7I A;  4MC0 A;  4GA3 A;  2AET A;  2F89 F;  3OAC A;  2VF6 A;  5KSX F;  4JVJ F;  4NG6 A;  3KRA B;  3WCJ A;  3ZMB A;  1YV5 A;  5AFX A;  3P5P A;  2PS6 A;  5JA0 F;  5C05 A;  5B01 A;  4NFJ F;  3Q1O A;  2F92 F;  2Z4V A;  5DGM F;  4JZB A;  5ILH A;  3N0G A;  5B03 A;  2E8U A;  5B0M A;  3WEH A;  1WY0 A;  4NUA A;  5ILZ A;  4NKE A;  1KIZ A;  3PH7 A;  1HXC A;  4KWD A;  3AQ0 A;  1WL1 A;  5DJP F;  4KPD A;  5ILK A;  1WL3 A;  3LLW A;  3WEI A;  2I19 A;  1N21 A;  3NRI A;  3VJ8 A;  4E1E A;  2RAH A;  2J1O A;  3V66 A;  1YYT A;  5JV1 F;  1YHK A;  2OGD A;  3OAB B;  3OAC B;  2PS8 A;  3AQB B;  3LEE A;  4KUX A;  1UBV A;  3WCL A;  4XQR F;  1HM7 A;  2F8C F;  3APZ A;  3N6K F;  3M01 A;  4KFA A;  1V4H A;  3PYA A;  1YHL A;  5EAU A;  5ERN A;  3DYF A;  1N1Z A;  2AZL A;  3WCM A;  5CG5 A;  3N0F A;  3WEJ A;  5DHI A;  2ZY1 A;  3CP6 A;  4LPH F;  1YYS A;  4UMJ A;  4E9Z A;  3ADZ A;  5IK0 A;  2OA6 A;  1HX9 A;  3EZ3 A;  3N5H F;  4P0W A;  3WCI A;  3RBM A;  1N24 A;  4FP4 A;  5JV2 F;  3OYR A;  3SDT A;  4RXD A;  4N9U A;  2ZCS A;  5DJV F;  4KVD A;  2E8T A;  3N45 F;  3WEF A;  5HN9 A;  4QPF A;  4KK2 A;  4PVX F;  3RYW A;  2ZEU A;  3QQV A;  2F8Z F;  3LJI A;  4EA1 A;  3WEK A;  2P1C A;  3S4J A;  3QKC A;  4EA2 A;  3S9V A;  2E4O A;  3KRO A;  4MC3 A;  3DYG A;  3KRF B;  1DI1 A;  3Q2Q A;  4KPJ A;  2E93 A;  2AZK A;  3NPK A;  1KIY A;  3WCB A;  3M00 A;  4LZ3 A;  3WCD A;  1YHM A;  2FOR A;  4RXE A;  3KRC A;  5IMN A;  5I1U A;  3ACW A;  4LFE A;  3M02 A;  5B0I A;  2Z4W A;  4OKZ A;  3V1X A;  3G4F A;  3WCG A;  3KRP A;  3P8L A;  4GAX A;  3N1W F;  4DWG A;  3NPR A;  1WMW A;  2ZCR A;  5ERM A;  2E90 A;  1UBW A;  2ONH A;  2F94 F;  4MC8 A;  2Q58 A;  5DHK A;  5ER8 A;  5IMP A;  2Q9Z A;  4KVI A;  4LTV A;  5EAT A;  3V1V A;  1N23 A;  3LVS A;  4LLS A;  1RQJ A;  5JV0 F;  3AE0 A;  2E94 A;  4JXN A;  3EFQ A;  1HXA A;  3ASX A;  2AZJ A;  2ZEV A;  2ZCO A;  3WCE A;  5B0K A;  4OGU A;  1ZW5 A;  1WL2 A;  3TC1 A;  4K10 A;  5IK6 A;  3ICK A;  4DWB A;  5B0L A;  4JXY A;  3WSB A;  1VG3 A;  5ILI A;  3CC9 A;  1N22 A;  3M9U A;  4FJQ A;  3Q30 A;  3WJN A;  3LGK A;  3VJD A;  1V4I A;  3EGT A;  3WCH A;  1EZF A;  4OMG A;  5AHU B;  4P0V A;  3B7L A;  3WJO A;  2ZCQ A;  4KVY A;  5HNA A;  2DH4 A;  3BNY A;  4LPG F;  5A0I A;  3ZMC A;  3LMD A;  5B0J A;  3WEG A;  4LLT A;  3W7F A;  3N46 F;  2J1P A;  3P5R A;  5E8L A;  3LZ9 A;  2PS5 A;  4DZW A;  2F7M F;  2OPN A;  3N3L F;  5IMI A;  4H5C F;  3ACY A;  4GP1 A;  3P41 A;  1VG6 A;  3TFN A;  2QIS A;  3VJA A;  4XQT F;  1UBX A;  5ILD A;  3SDU A;  5AYP A;  1WL0 A;  2PS7 A;  5A0K A;  1HXG A;  4KVW A;  1YQ7 A;  1V4J A;  1WKZ A;  4LTZ A;  4F6V A;  3BNX A;  3IPI A;  4RNQ A;  5DIQ F;  3SDQ A;  3ZOU A;  5IL3 A;  4GP2 A;  3KRA A;  4Q23 A;  4KQ5 A;  3WJK A;  2E8V A;  5B00 A;  3LOM A;  4LFV F;  3ICN A;  4NKF A;  3ICM A;  3KBK A;  4EA0 A;  3N49 F;  3PKO A;  4LUU A;  4QXS F;  3ZCD A;  3G4D A;  3PYB A;  5DGN F;  3P8R A;  4H5D F;  3CKE A;  3WCA A;  5HN8 A;  2EWG A;  4F6X A;  5IL8 A;  4DHD A;  1V4K A;  1UBY A;  3N1V F;  3PDE A;  5IM1 A;  5H9D A;  2Z78 A;  3WCC A;  1VG4 A;  3KRO B;  5JUZ F;  2F9K F;  3LGZ B;  3N3D A;  5IKA A;  3OAB A;  1V4E A;  3N5J F;  4KQS A;  3KRC B;  2FTZ A;  2Z7H A;  2OPM A;  4LIX A;  2O1O A;  3UCA A;  1DGP A;  3TFV A;  3KRP B;  2AEK A;  2J5C A;  3LK5 A;  3WE9 A;  1JFG A;  5A0J A;  3LDW A;  1N20 A;  4RXA A;  3VJE A;  5ILY A;  4WK5 A;  3SDR A;  4LA6 A;  3MZV A;  3WCF A;  1N1B A;  1HM4 A;  1YYU A;  1PS1 A;  3TS7 A;  3ACX A;  5IVG A;  5ERO A;  3LSN A;  1FPS A;  4OMH A;  4RXC A;  3DYH A;  3WC9 A;  4JZX A;  4XQS F;  3NF2 A;  4RYP A;  2AEL A;  4KQU A;  4OKM A;  5IK9 A;  5HN7 A;  3KRF A;  4N1Z F;  5E8K A;  2E8W A;  3RMG A;  3TFP A;  4KKM A;  4LZC A;  5IN8 A;  2Q9Y A;  3RYE A;  4LA5 A;  1VG2 A;  4H5E F;  2Z4X A;  2E91 A;  2E8X A;  2PS4 A;  5ILJ A;  2Z50 A;  4LXW A;  4PVY F;  3LG5 A;  4DXJ A;  5DZ2 A;  2Q80 A;  5CG6 A;  2Z4Z A;  2H8O A;  2Z4Y A;  5B02 A;  4L2X F;  4DI5 A;  3IBA A;  3SDV A;  5DW7 A;  2Z52 A;  4E9U A;  3AQC B;  3WSA A;  4DEM F;  4P0X A;  4JYX A;  3VJ9 A;  5DGS F;  4LOB A;  1YYQ A;  5EAS A;  1YJ4 A;  4NFI F;  2ONG A;  4HD1 A;  5AEL A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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