3N5HF

Human fpps complex with nov_304
Total Genus 138
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
138
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE
total genus 138
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2010-05-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3n5hF00
3ZOUA 5E8HA 3PYBA 5C05A 3G4DA 1PS1A 4LUUA 4DWGA 1V4IA 2Q58A 3ADZA 4LZCA 4H5EF 2Z4YA 3PKOA 3ASXA 4GP1A 5DHIA 3LK5A 3G4FA 3TFNA 3DYHA 3TFPA 2AZKA 5A0KA 3MAVA 4OMGA 5IN8A 3N1WF 3P8RA 1UBWA 3SDQA 4KVDA 2OA6A 5EROA 1YJ4A 3M00A 5DIQF 5H9DA 3VJ8A 2Z50A 3N3LF 5B0IA 3ZCDA 3N49F 3AQCB 5ILJA 1N1BA 4E1EA 2I19A 1ZW5A 4JYXA 3WJKA 2PS8A 4LOBA 1YHLA 2ZEVA 3VJBA 4EA1A 4F6VA 3OACA 2Z4ZA 5JV0F 3NRIA 3ZMCA 1N20A 3VJEA 2E90A 2J5CA 3M9UA 5DW7A 2F8CF 4KQUA 3KB9A 2VF6A 1VG7A 4KUXA 3OABB 4NUAA 1HXGA 4NKEA 3N1VF 3N3DA 4LZ0A 4OMHA 5HN8A 3KROA 3P41A 3LVSA 3M0GA 3ICMA 2Z7IA 3WCIA 4KWDA 3ACYA 3KRFA 4DWBA 3LGZB 1HXAA 3WJNA 4K10A 2Z78A 4LPGF 4LLTA 2E4OA 3LMDA 4RXAA 3VJCA 2Z4VA 3N45F 2P1CA 3WJOA 2Q9ZA 5IKAA 5B03A 4RXDA 5ER8A 4JZBA 3APZA 3WCJA 4KVIA 3DYGA 2ZEUA 4NFIF 2E8UA 1N21A 2H8OA 5DJPF 4Q23A 2ZCSA 5DZ2A 4E9UA 4OKZA 2E95A 1JFAA 3BNYA 1YQ7A 4QPFA 3NF2A 4LLSA 4XQTF 2FTZA 1DI1A 3KRCB 3LZ9A 5A0IA 3WCMA 5CG6A 3WEGA 3LJIA 1JFGA 5I1UA 2AETA 1YYSA 3MZVA 4DZWA 4OKMA 2PS5A 3SDTA 3Q2ZA 3W7FA 2ONHA 3UCAA 4L2XF 3WCDA 4ZQ8A 3RBMA 3P8LA 2E93A 3SDRA 1WL3A 3KBKA 2AEKA 1N24A 3EZ3A 3OABA 3VJDA 2AZJA 4DEMF 2F89F 1N1ZA 5IL3A 1WL1A 1UBVA 3WCEA 3LDWA 5DHKA 3M02A 1RQIA 1YYTA 1HM7A 5IMNA 4EA0A 4P0VA 2E8WA 5AFXA 5IMIA 5JV2F 4LA6A 4P0WA 5EAUA 2ZCRA 3LGKA 3Q30A 4H5DF 5ILZA 2AZLA 2RAHA 3LG5A 3OYRA 1YYRA 3ZMBA 3N46F 3EGTA 3AE0A 2ONGA 5AYPA 3KRAA 3ACWA 2J1PA 5IK6A 3WEIA 3KRPB 2ZCQA 1V4EA 4KFAA 4N1ZF 3SAEA 3OACB 2PS7A 5CG5A 4KKMA 4LPHF 1N23A 3N5HF 3WEHA 3WSBA 5ILYA 3RYWA 2PS4A 3NPKA 3AQ0A 2Z7HA 2O1OA 4KVYA 1V4HA 4KPDA 3WEFA 1YHMA 4XQSF 4F6XA 3LEEA 3P5PA 4RYPA 5EASA 4DI5A 4KPJA 3RYEA 3QQVA 2Q9YA 4QXSF 5JV1F 3IBAA 3CC9A 5AELA 5B0KA 3WSAA 5HNAA 5B0MA 3LOMA 2Q80A 1YV5A 5ILDA 3B7LA 5A0JA 3WCCA 3VJAA 1V4JA 4RXCA 4HD1A 4PVYF 3RMGA 3AQBB 1WMWA 5B02A 3WC9A 1WKZA 4OGUA 1HM4A 3WEKA 1WL0A 3ID0A 2OPNA 5ILIA 2DH4A 3WCGA 3QKCA 5AHUB 4GA3A 2PS6A 4JZXA 1YYUA 1WL2A 3N0FA 4NFKF 3TS7A 5JA0F 3V1XA 5ERNA 4RXEA 3ZL6A 4E9ZA 3CKEA 5HN9A 1YYQA 4MC8A 2AELA 4LTZA 4UMJA 1VG2A 2EWGA 3BNXA 5EATA 3N5JF 2E92A 4NFJF 1KIYA 3V66A 4F62A 1RQJA 3PYAA 5ILHA 3SDVA 3TFVA 2OGDA 4MC0A 4FP4A 4P0XA 1UBYA 1YHKA 4H5CF 4FJQA 4JVJF 4PVXF 3Q2QA 4LA5A 3ICNA 4RNQA 3WCLA 2ZY1A 4N9UA 3KRPA 3P5RA 2Z52A 2J1OA 3Q1OA 4JXNA 2Z4WA 5DGSF 2F92F 3WCAA 4LFGA 2F9KF 5IVGA 5DGMF 5DGNF 3VJ9A 5JUZF 4NKFA 5IKHA 3DYFA 5KSXF 4GAXA 5B01A 2F94F 4WK5A 3ACXA 5B0JA 5IK0A 5HN7A 3WCHA 5DJVF 3N6KF 4JXYA 4DXJA 1UBXA 5IK9A 4DHDA 3LSNA 4LFVF 3V1VA 5DJRF 5B00A 3M01A 1VG3A 2F7MF 3PDEA 4LXWA 1DGPA 3KROB 4KQSA 3IPIA 4XQRF 3CP6A 2F8ZF 3NPRA 2QISA 3KRAB 5IL8A 4LIXA 4LZ3A 2OPMA 5E8KA 3WCFA 3KRFB 1HX9A 3KRCA 4GP2A 1N22A 4MC3A 1EZFA 3S4JA 2E8VA 1KIZA 3SDUA 4KVWA 3ICKA 3N0GA 3PH7A 2ZCOA 2E94A 1FPSA 1VG4A 4KQ5A 3LLWA 4NG6A 5IMPA 2E91A 4EA2A 2E8XA 3ICZA 4LFEA 5B0LA 3WCBA 4KK2A 2Z4XA 5ERMA 3WEJA 2E8TA 3EFQA 5ILKA 3TC1A 1V4KA 5IM1A 2FORA 3S9VA 4LTVA 5E8LA 1WY0A 3WE9A 1HXCA 1VG6A 1RTRA
chains in the Genus database with same CATH superfamily
3ZOUA 5E8HA 3PYBA 5C05A 3G4DA 1PS1A 4LUUA 4DWGA 1V4IA 2Q58A 3ADZA 4LZCA 4H5EF 2Z4YA 3PKOA 3ASXA 4GP1A 5DHIA 3LK5A 3G4FA 3TFNA 3DYHA 3TFPA 2AZKA 5A0KA 3MAVA 4OMGA 5IN8A 3N1WF 3P8RA 1UBWA 3SDQA 4KVDA 2OA6A 5EROA 1YJ4A 3M00A 5DIQF 5H9DA 3VJ8A 2Z50A 3N3LF 5B0IA 3ZCDA 3N49F 3AQCB 5ILJA 1N1BA 4E1EA 2I19A 1ZW5A 4JYXA 3WJKA 2PS8A 4LOBA 1YHLA 2ZEVA 3VJBA 4EA1A 4F6VA 3OACA 2Z4ZA 5JV0F 3NRIA 3ZMCA 1N20A 3VJEA 2E90A 2J5CA 3M9UA 5DW7A 2F8CF 4KQUA 3KB9A 2VF6A 1VG7A 4KUXA 3OABB 4NUAA 1HXGA 4NKEA 3N1VF 3N3DA 4LZ0A 4OMHA 5HN8A 3KROA 3P41A 3LVSA 3M0GA 3ICMA 2Z7IA 3WCIA 4KWDA 3ACYA 3KRFA 4DWBA 3LGZB 1HXAA 3WJNA 4K10A 2Z78A 4LPGF 4LLTA 2E4OA 3LMDA 4RXAA 3VJCA 2Z4VA 3N45F 2P1CA 3WJOA 2Q9ZA 5IKAA 5B03A 4RXDA 5ER8A 4JZBA 3APZA 3WCJA 4KVIA 3DYGA 2ZEUA 4NFIF 2E8UA 1N21A 2H8OA 5DJPF 4Q23A 2ZCSA 5DZ2A 4E9UA 4OKZA 2E95A 1JFAA 3BNYA 1YQ7A 4QPFA 3NF2A 4LLSA 4XQTF 2FTZA 1DI1A 3KRCB 3LZ9A 5A0IA 3WCMA 5CG6A 3WEGA 3LJIA 1JFGA 5I1UA 2AETA 1YYSA 3MZVA 4DZWA 4OKMA 2PS5A 3SDTA 3Q2ZA 3W7FA 2ONHA 3UCAA 4L2XF 3WCDA 4ZQ8A 3RBMA 3P8LA 2E93A 3SDRA 1WL3A 3KBKA 2AEKA 1N24A 3EZ3A 3OABA 3VJDA 2AZJA 4DEMF 2F89F 1N1ZA 5IL3A 1WL1A 1UBVA 3WCEA 3LDWA 5DHKA 3M02A 1RQIA 1YYTA 1HM7A 5IMNA 4EA0A 4P0VA 2E8WA 5AFXA 5IMIA 5JV2F 4LA6A 4P0WA 5EAUA 2ZCRA 3LGKA 3Q30A 4H5DF 5ILZA 2AZLA 2RAHA 3LG5A 3OYRA 1YYRA 3ZMBA 3N46F 3EGTA 3AE0A 2ONGA 5AYPA 3KRAA 3ACWA 2J1PA 5IK6A 3WEIA 3KRPB 2ZCQA 1V4EA 4KFAA 4N1ZF 3SAEA 3OACB 2PS7A 5CG5A 4KKMA 4LPHF 1N23A 3N5HF 3WEHA 3WSBA 5ILYA 3RYWA 2PS4A 3NPKA 3AQ0A 2Z7HA 2O1OA 4KVYA 1V4HA 4KPDA 3WEFA 1YHMA 4XQSF 4F6XA 3LEEA 3P5PA 4RYPA 5EASA 4DI5A 4KPJA 3RYEA 3QQVA 2Q9YA 4QXSF 5JV1F 3IBAA 3CC9A 5AELA 5B0KA 3WSAA 5HNAA 5B0MA 3LOMA 2Q80A 1YV5A 5ILDA 3B7LA 5A0JA 3WCCA 3VJAA 1V4JA 4RXCA 4HD1A 4PVYF 3RMGA 3AQBB 1WMWA 5B02A 3WC9A 1WKZA 4OGUA 1HM4A 3WEKA 1WL0A 3ID0A 2OPNA 5ILIA 2DH4A 3WCGA 3QKCA 5AHUB 4GA3A 2PS6A 4JZXA 1YYUA 1WL2A 3N0FA 4NFKF 3TS7A 5JA0F 3V1XA 5ERNA 4RXEA 3ZL6A 4E9ZA 3CKEA 5HN9A 1YYQA 4MC8A 2AELA 4LTZA 4UMJA 1VG2A 2EWGA 3BNXA 5EATA 3N5JF 2E92A 4NFJF 1KIYA 3V66A 4F62A 1RQJA 3PYAA 5ILHA 3SDVA 3TFVA 2OGDA 4MC0A 4FP4A 4P0XA 1UBYA 1YHKA 4H5CF 4FJQA 4JVJF 4PVXF 3Q2QA 4LA5A 3ICNA 4RNQA 3WCLA 2ZY1A 4N9UA 3KRPA 3P5RA 2Z52A 2J1OA 3Q1OA 4JXNA 2Z4WA 5DGSF 2F92F 3WCAA 4LFGA 2F9KF 5IVGA 5DGMF 5DGNF 3VJ9A 5JUZF 4NKFA 5IKHA 3DYFA 5KSXF 4GAXA 5B01A 2F94F 4WK5A 3ACXA 5B0JA 5IK0A 5HN7A 3WCHA 5DJVF 3N6KF 4JXYA 4DXJA 1UBXA 5IK9A 4DHDA 3LSNA 4LFVF 3V1VA 5DJRF 5B00A 3M01A 1VG3A 2F7MF 3PDEA 4LXWA 1DGPA 3KROB 4KQSA 3IPIA 4XQRF 3CP6A 2F8ZF 3NPRA 2QISA 3KRAB 5IL8A 4LIXA 4LZ3A 2OPMA 5E8KA 3WCFA 3KRFB 1HX9A 3KRCA 4GP2A 1N22A 4MC3A 1EZFA 3S4JA 2E8VA 1KIZA 3SDUA 4KVWA 3ICKA 3N0GA 3PH7A 2ZCOA 2E94A 1FPSA 1VG4A 4KQ5A 3LLWA 4NG6A 5IMPA 2E91A 4EA2A 2E8XA 3ICZA 4LFEA 5B0LA 3WCBA 4KK2A 2Z4XA 5ERMA 3WEJA 2E8TA 3EFQA 5ILKA 3TC1A 1V4KA 5IM1A 2FORA 3S9VA 4LTVA 5E8LA 1WY0A 3WE9A 1HXCA 1VG6A 1RTRA
chains in the Genus database with same CATH topology
3ZOUA 5E8HA 3PYBA 5C05A 3G4DA 1PS1A 4LUUA 4DWGA 1V4IA 2Q58A 3ADZA 4LZCA 4H5EF 2Z4YA 3PKOA 3ASXA 4GP1A 5DHIA 3LK5A 3G4FA 3TFNA 3DYHA 3TFPA 2AZKA 5A0KA 3MAVA 4OMGA 5IN8A 3N1WF 3P8RA 1UBWA 3SDQA 4KVDA 2OA6A 5EROA 1YJ4A 3M00A 5DIQF 5H9DA 3VJ8A 2Z50A 3N3LF 5B0IA 3ZCDA 3N49F 3AQCB 5ILJA 1N1BA 4E1EA 2I19A 1ZW5A 4JYXA 3WJKA 2PS8A 4LOBA 1YHLA 2ZEVA 3VJBA 4EA1A 4F6VA 3OACA 2Z4ZA 5JV0F 3NRIA 3ZMCA 1N20A 3VJEA 2E90A 2J5CA 3M9UA 5DW7A 2F8CF 4KQUA 3KB9A 2VF6A 1VG7A 4KUXA 3OABB 4NUAA 1HXGA 4NKEA 3N1VF 3N3DA 4LZ0A 4OMHA 5HN8A 3KROA 3P41A 3LVSA 3M0GA 3ICMA 2Z7IA 3WCIA 4KWDA 3ACYA 3KRFA 4DWBA 3LGZB 1HXAA 3WJNA 4K10A 2Z78A 4LPGF 4LLTA 2E4OA 3LMDA 4RXAA 3VJCA 2Z4VA 3N45F 2P1CA 3WJOA 2Q9ZA 5IKAA 5B03A 4RXDA 5ER8A 4JZBA 3APZA 3WCJA 4KVIA 3DYGA 2ZEUA 4NFIF 2E8UA 1N21A 2H8OA 5DJPF 4Q23A 2ZCSA 5DZ2A 4E9UA 4OKZA 2E95A 1JFAA 3BNYA 1YQ7A 4QPFA 3NF2A 4LLSA 4XQTF 2FTZA 1DI1A 3KRCB 3LZ9A 5A0IA 3WCMA 5CG6A 3WEGA 3LJIA 1JFGA 5I1UA 2AETA 1YYSA 3MZVA 4DZWA 4OKMA 2PS5A 3SDTA 3Q2ZA 3W7FA 2ONHA 3UCAA 4L2XF 3WCDA 4ZQ8A 3RBMA 3P8LA 2E93A 3SDRA 1WL3A 3KBKA 2AEKA 1N24A 3EZ3A 3OABA 3VJDA 2AZJA 4DEMF 2F89F 1N1ZA 5IL3A 1WL1A 1UBVA 3WCEA 3LDWA 5DHKA 3M02A 1RQIA 1YYTA 1HM7A 5IMNA 4EA0A 4P0VA 2E8WA 5AFXA 5IMIA 5JV2F 4LA6A 4P0WA 5EAUA 2ZCRA 3LGKA 3Q30A 4H5DF 5ILZA 2AZLA 2RAHA 3LG5A 3OYRA 1YYRA 3ZMBA 3N46F 3EGTA 3AE0A 2ONGA 5AYPA 3KRAA 3ACWA 2J1PA 5IK6A 3WEIA 3KRPB 2ZCQA 1V4EA 4KFAA 4N1ZF 3SAEA 3OACB 2PS7A 5CG5A 4KKMA 4LPHF 1N23A 3N5HF 3WEHA 3WSBA 5ILYA 3RYWA 2PS4A 3NPKA 3AQ0A 2Z7HA 2O1OA 4KVYA 1V4HA 4KPDA 3WEFA 1YHMA 4XQSF 4F6XA 3LEEA 3P5PA 4RYPA 5EASA 4DI5A 4KPJA 3RYEA 3QQVA 2Q9YA 4QXSF 5JV1F 3IBAA 3CC9A 5AELA 5B0KA 3WSAA 5HNAA 5B0MA 3LOMA 2Q80A 1YV5A 5ILDA 3B7LA 5A0JA 3WCCA 3VJAA 1V4JA 4RXCA 4HD1A 4PVYF 3RMGA 3AQBB 1WMWA 5B02A 3WC9A 1WKZA 4OGUA 1HM4A 3WEKA 1WL0A 3ID0A 2OPNA 5ILIA 2DH4A 3WCGA 3QKCA 5AHUB 4GA3A 2PS6A 4JZXA 1YYUA 1WL2A 3N0FA 4NFKF 3TS7A 5JA0F 3V1XA 5ERNA 4RXEA 3ZL6A 4E9ZA 3CKEA 5HN9A 1YYQA 4MC8A 2AELA 4LTZA 4UMJA 1VG2A 2EWGA 3BNXA 5EATA 3N5JF 2E92A 4NFJF 1KIYA 3V66A 4F62A 1RQJA 3PYAA 5ILHA 3SDVA 3TFVA 2OGDA 4MC0A 4FP4A 4P0XA 1UBYA 1YHKA 4H5CF 4FJQA 4JVJF 4PVXF 3Q2QA 4LA5A 3ICNA 4RNQA 3WCLA 2ZY1A 4N9UA 3KRPA 3P5RA 2Z52A 2J1OA 3Q1OA 4JXNA 2Z4WA 5DGSF 2F92F 3WCAA 4LFGA 2F9KF 5IVGA 5DGMF 5DGNF 3VJ9A 5JUZF 4NKFA 5IKHA 3DYFA 5KSXF 4GAXA 5B01A 2F94F 4WK5A 3ACXA 5B0JA 5IK0A 5HN7A 3WCHA 5DJVF 3N6KF 4JXYA 4DXJA 1UBXA 5IK9A 4DHDA 3LSNA 4LFVF 3V1VA 5DJRF 5B00A 3M01A 1VG3A 2F7MF 3PDEA 4LXWA 1DGPA 3KROB 4KQSA 3IPIA 4XQRF 3CP6A 2F8ZF 3NPRA 2QISA 3KRAB 5IL8A 4LIXA 4LZ3A 2OPMA 5E8KA 3WCFA 3KRFB 1HX9A 3KRCA 4GP2A 1N22A 4MC3A 1EZFA 3S4JA 2E8VA 1KIZA 3SDUA 4KVWA 3ICKA 3N0GA 3PH7A 2ZCOA 2E94A 1FPSA 1VG4A 4KQ5A 3LLWA 4NG6A 5IMPA 2E91A 4EA2A 2E8XA 3ICZA 4LFEA 5B0LA 3WCBA 4KK2A 2Z4XA 5ERMA 3WEJA 2E8TA 3EFQA 5ILKA 3TC1A 1V4KA 5IM1A 2FORA 3S9VA 4LTVA 5E8LA 1WY0A 3WE9A 1HXCA 1VG6A 1RTRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZOU A;  5E8H A;  3PYB A;  5C05 A;  3G4D A;  1PS1 A;  4LUU A;  4DWG A;  1V4I A;  2Q58 A;  3ADZ A;  4LZC A;  4H5E F;  2Z4Y A;  3PKO A;  3ASX A;  4GP1 A;  5DHI A;  3LK5 A;  3G4F A;  3TFN A;  3DYH A;  3TFP A;  2AZK A;  5A0K A;  3MAV A;  4OMG A;  5IN8 A;  3N1W F;  3P8R A;  1UBW A;  3SDQ A;  4KVD A;  2OA6 A;  5ERO A;  1YJ4 A;  3M00 A;  5DIQ F;  5H9D A;  3VJ8 A;  2Z50 A;  3N3L F;  5B0I A;  3ZCD A;  3N49 F;  3AQC B;  5ILJ A;  1N1B A;  4E1E A;  2I19 A;  1ZW5 A;  4JYX A;  3WJK A;  2PS8 A;  4LOB A;  1YHL A;  2ZEV A;  3VJB A;  4EA1 A;  4F6V A;  3OAC A;  2Z4Z A;  5JV0 F;  3NRI A;  3ZMC A;  1N20 A;  3VJE A;  2E90 A;  2J5C A;  3M9U A;  5DW7 A;  2F8C F;  4KQU A;  3KB9 A;  2VF6 A;  1VG7 A;  4KUX A;  3OAB B;  4NUA A;  1HXG A;  4NKE A;  3N1V F;  3N3D A;  4LZ0 A;  4OMH A;  5HN8 A;  3KRO A;  3P41 A;  3LVS A;  3M0G A;  3ICM A;  2Z7I A;  3WCI A;  4KWD A;  3ACY A;  3KRF A;  4DWB A;  3LGZ B;  1HXA A;  3WJN A;  4K10 A;  2Z78 A;  4LPG F;  4LLT A;  2E4O A;  3LMD A;  4RXA A;  3VJC A;  2Z4V A;  3N45 F;  2P1C A;  3WJO A;  2Q9Z A;  5IKA A;  5B03 A;  4RXD A;  5ER8 A;  4JZB A;  3APZ A;  3WCJ A;  4KVI A;  3DYG A;  2ZEU A;  4NFI F;  2E8U A;  1N21 A;  2H8O A;  5DJP F;  4Q23 A;  2ZCS A;  5DZ2 A;  4E9U A;  4OKZ A;  2E95 A;  1JFA A;  3BNY A;  1YQ7 A;  4QPF A;  3NF2 A;  4LLS A;  4XQT F;  2FTZ A;  1DI1 A;  3KRC B;  3LZ9 A;  5A0I A;  3WCM A;  5CG6 A;  3WEG A;  3LJI A;  1JFG A;  5I1U A;  2AET A;  1YYS A;  3MZV A;  4DZW A;  4OKM A;  2PS5 A;  3SDT A;  3Q2Z A;  3W7F A;  2ONH A;  3UCA A;  4L2X F;  3WCD A;  4ZQ8 A;  3RBM A;  3P8L A;  2E93 A;  3SDR A;  1WL3 A;  3KBK A;  2AEK A;  1N24 A;  3EZ3 A;  3OAB A;  3VJD A;  2AZJ A;  4DEM F;  2F89 F;  1N1Z A;  5IL3 A;  1WL1 A;  1UBV A;  3WCE A;  3LDW A;  5DHK A;  3M02 A;  1RQI A;  1YYT A;  1HM7 A;  5IMN A;  4EA0 A;  4P0V A;  2E8W A;  5AFX A;  5IMI A;  5JV2 F;  4LA6 A;  4P0W A;  5EAU A;  2ZCR A;  3LGK A;  3Q30 A;  4H5D F;  5ILZ A;  2AZL A;  2RAH A;  3LG5 A;  3OYR A;  1YYR A;  3ZMB A;  3N46 F;  3EGT A;  3AE0 A;  2ONG A;  5AYP A;  3KRA A;  3ACW A;  2J1P A;  5IK6 A;  3WEI A;  3KRP B;  2ZCQ A;  1V4E A;  4KFA A;  4N1Z F;  3SAE A;  3OAC B;  2PS7 A;  5CG5 A;  4KKM A;  4LPH F;  1N23 A;  3N5H F;  3WEH A;  3WSB A;  5ILY A;  3RYW A;  2PS4 A;  3NPK A;  3AQ0 A;  2Z7H A;  2O1O A;  4KVY A;  1V4H A;  4KPD A;  3WEF A;  1YHM A;  4XQS F;  4F6X A;  3LEE A;  3P5P A;  4RYP A;  5EAS A;  4DI5 A;  4KPJ A;  3RYE A;  3QQV A;  2Q9Y A;  4QXS F;  5JV1 F;  3IBA A;  3CC9 A;  5AEL A;  5B0K A;  3WSA A;  5HNA A;  5B0M A;  3LOM A;  2Q80 A;  1YV5 A;  5ILD A;  3B7L A;  5A0J A;  3WCC A;  3VJA A;  1V4J A;  4RXC A;  4HD1 A;  4PVY F;  3RMG A;  3AQB B;  1WMW A;  5B02 A;  3WC9 A;  1WKZ A;  4OGU A;  1HM4 A;  3WEK A;  1WL0 A;  3ID0 A;  2OPN A;  5ILI A;  2DH4 A;  3WCG A;  3QKC A;  5AHU B;  4GA3 A;  2PS6 A;  4JZX A;  1YYU A;  1WL2 A;  3N0F A;  4NFK F;  3TS7 A;  5JA0 F;  3V1X A;  5ERN A;  4RXE A;  3ZL6 A;  4E9Z A;  3CKE A;  5HN9 A;  1YYQ A;  4MC8 A;  2AEL A;  4LTZ A;  4UMJ A;  1VG2 A;  2EWG A;  3BNX A;  5EAT A;  3N5J F;  2E92 A;  4NFJ F;  1KIY A;  3V66 A;  4F62 A;  1RQJ A;  3PYA A;  5ILH A;  3SDV A;  3TFV A;  2OGD A;  4MC0 A;  4FP4 A;  4P0X A;  1UBY A;  1YHK A;  4H5C F;  4FJQ A;  4JVJ F;  4PVX F;  3Q2Q A;  4LA5 A;  3ICN A;  4RNQ A;  3WCL A;  2ZY1 A;  4N9U A;  3KRP A;  3P5R A;  2Z52 A;  2J1O A;  3Q1O A;  4JXN A;  2Z4W A;  5DGS F;  2F92 F;  3WCA A;  4LFG A;  2F9K F;  5IVG A;  5DGM F;  5DGN F;  3VJ9 A;  5JUZ F;  4NKF A;  5IKH A;  3DYF A;  5KSX F;  4GAX A;  5B01 A;  2F94 F;  4WK5 A;  3ACX A;  5B0J A;  5IK0 A;  5HN7 A;  3WCH A;  5DJV F;  3N6K F;  4JXY A;  4DXJ A;  1UBX A;  5IK9 A;  4DHD A;  3LSN A;  4LFV F;  3V1V A;  5DJR F;  5B00 A;  3M01 A;  1VG3 A;  2F7M F;  3PDE A;  4LXW A;  1DGP A;  3KRO B;  4KQS A;  3IPI A;  4XQR F;  3CP6 A;  2F8Z F;  3NPR A;  2QIS A;  3KRA B;  5IL8 A;  4LIX A;  4LZ3 A;  2OPM A;  5E8K A;  3WCF A;  3KRF B;  1HX9 A;  3KRC A;  4GP2 A;  1N22 A;  4MC3 A;  1EZF A;  3S4J A;  2E8V A;  1KIZ A;  3SDU A;  4KVW A;  3ICK A;  3N0G A;  3PH7 A;  2ZCO A;  2E94 A;  1FPS A;  1VG4 A;  4KQ5 A;  3LLW A;  4NG6 A;  5IMP A;  2E91 A;  4EA2 A;  2E8X A;  3ICZ A;  4LFE A;  5B0L A;  3WCB A;  4KK2 A;  2Z4X A;  5ERM A;  3WEJ A;  2E8T A;  3EFQ A;  5ILK A;  3TC1 A;  1V4K A;  5IM1 A;  2FOR A;  3S9V A;  4LTV A;  5E8L A;  1WY0 A;  3WE9 A;  1HXC A;  1VG6 A;  1RTR A; 
#chains in the Genus database with same CATH topology
 3ZOU A;  5E8H A;  3PYB A;  5C05 A;  3G4D A;  1PS1 A;  4LUU A;  4DWG A;  1V4I A;  2Q58 A;  3ADZ A;  4LZC A;  4H5E F;  2Z4Y A;  3PKO A;  3ASX A;  4GP1 A;  5DHI A;  3LK5 A;  3G4F A;  3TFN A;  3DYH A;  3TFP A;  2AZK A;  5A0K A;  3MAV A;  4OMG A;  5IN8 A;  3N1W F;  3P8R A;  1UBW A;  3SDQ A;  4KVD A;  2OA6 A;  5ERO A;  1YJ4 A;  3M00 A;  5DIQ F;  5H9D A;  3VJ8 A;  2Z50 A;  3N3L F;  5B0I A;  3ZCD A;  3N49 F;  3AQC B;  5ILJ A;  1N1B A;  4E1E A;  2I19 A;  1ZW5 A;  4JYX A;  3WJK A;  2PS8 A;  4LOB A;  1YHL A;  2ZEV A;  3VJB A;  4EA1 A;  4F6V A;  3OAC A;  2Z4Z A;  5JV0 F;  3NRI A;  3ZMC A;  1N20 A;  3VJE A;  2E90 A;  2J5C A;  3M9U A;  5DW7 A;  2F8C F;  4KQU A;  3KB9 A;  2VF6 A;  1VG7 A;  4KUX A;  3OAB B;  4NUA A;  1HXG A;  4NKE A;  3N1V F;  3N3D A;  4LZ0 A;  4OMH A;  5HN8 A;  3KRO A;  3P41 A;  3LVS A;  3M0G A;  3ICM A;  2Z7I A;  3WCI A;  4KWD A;  3ACY A;  3KRF A;  4DWB A;  3LGZ B;  1HXA A;  3WJN A;  4K10 A;  2Z78 A;  4LPG F;  4LLT A;  2E4O A;  3LMD A;  4RXA A;  3VJC A;  2Z4V A;  3N45 F;  2P1C A;  3WJO A;  2Q9Z A;  5IKA A;  5B03 A;  4RXD A;  5ER8 A;  4JZB A;  3APZ A;  3WCJ A;  4KVI A;  3DYG A;  2ZEU A;  4NFI F;  2E8U A;  1N21 A;  2H8O A;  5DJP F;  4Q23 A;  2ZCS A;  5DZ2 A;  4E9U A;  4OKZ A;  2E95 A;  1JFA A;  3BNY A;  1YQ7 A;  4QPF A;  3NF2 A;  4LLS A;  4XQT F;  2FTZ A;  1DI1 A;  3KRC B;  3LZ9 A;  5A0I A;  3WCM A;  5CG6 A;  3WEG A;  3LJI A;  1JFG A;  5I1U A;  2AET A;  1YYS A;  3MZV A;  4DZW A;  4OKM A;  2PS5 A;  3SDT A;  3Q2Z A;  3W7F A;  2ONH A;  3UCA A;  4L2X F;  3WCD A;  4ZQ8 A;  3RBM A;  3P8L A;  2E93 A;  3SDR A;  1WL3 A;  3KBK A;  2AEK A;  1N24 A;  3EZ3 A;  3OAB A;  3VJD A;  2AZJ A;  4DEM F;  2F89 F;  1N1Z A;  5IL3 A;  1WL1 A;  1UBV A;  3WCE A;  3LDW A;  5DHK A;  3M02 A;  1RQI A;  1YYT A;  1HM7 A;  5IMN A;  4EA0 A;  4P0V A;  2E8W A;  5AFX A;  5IMI A;  5JV2 F;  4LA6 A;  4P0W A;  5EAU A;  2ZCR A;  3LGK A;  3Q30 A;  4H5D F;  5ILZ A;  2AZL A;  2RAH A;  3LG5 A;  3OYR A;  1YYR A;  3ZMB A;  3N46 F;  3EGT A;  3AE0 A;  2ONG A;  5AYP A;  3KRA A;  3ACW A;  2J1P A;  5IK6 A;  3WEI A;  3KRP B;  2ZCQ A;  1V4E A;  4KFA A;  4N1Z F;  3SAE A;  3OAC B;  2PS7 A;  5CG5 A;  4KKM A;  4LPH F;  1N23 A;  3N5H F;  3WEH A;  3WSB A;  5ILY A;  3RYW A;  2PS4 A;  3NPK A;  3AQ0 A;  2Z7H A;  2O1O A;  4KVY A;  1V4H A;  4KPD A;  3WEF A;  1YHM A;  4XQS F;  4F6X A;  3LEE A;  3P5P A;  4RYP A;  5EAS A;  4DI5 A;  4KPJ A;  3RYE A;  3QQV A;  2Q9Y A;  4QXS F;  5JV1 F;  3IBA A;  3CC9 A;  5AEL A;  5B0K A;  3WSA A;  5HNA A;  5B0M A;  3LOM A;  2Q80 A;  1YV5 A;  5ILD A;  3B7L A;  5A0J A;  3WCC A;  3VJA A;  1V4J A;  4RXC A;  4HD1 A;  4PVY F;  3RMG A;  3AQB B;  1WMW A;  5B02 A;  3WC9 A;  1WKZ A;  4OGU A;  1HM4 A;  3WEK A;  1WL0 A;  3ID0 A;  2OPN A;  5ILI A;  2DH4 A;  3WCG A;  3QKC A;  5AHU B;  4GA3 A;  2PS6 A;  4JZX A;  1YYU A;  1WL2 A;  3N0F A;  4NFK F;  3TS7 A;  5JA0 F;  3V1X A;  5ERN A;  4RXE A;  3ZL6 A;  4E9Z A;  3CKE A;  5HN9 A;  1YYQ A;  4MC8 A;  2AEL A;  4LTZ A;  4UMJ A;  1VG2 A;  2EWG A;  3BNX A;  5EAT A;  3N5J F;  2E92 A;  4NFJ F;  1KIY A;  3V66 A;  4F62 A;  1RQJ A;  3PYA A;  5ILH A;  3SDV A;  3TFV A;  2OGD A;  4MC0 A;  4FP4 A;  4P0X A;  1UBY A;  1YHK A;  4H5C F;  4FJQ A;  4JVJ F;  4PVX F;  3Q2Q A;  4LA5 A;  3ICN A;  4RNQ A;  3WCL A;  2ZY1 A;  4N9U A;  3KRP A;  3P5R A;  2Z52 A;  2J1O A;  3Q1O A;  4JXN A;  2Z4W A;  5DGS F;  2F92 F;  3WCA A;  4LFG A;  2F9K F;  5IVG A;  5DGM F;  5DGN F;  3VJ9 A;  5JUZ F;  4NKF A;  5IKH A;  3DYF A;  5KSX F;  4GAX A;  5B01 A;  2F94 F;  4WK5 A;  3ACX A;  5B0J A;  5IK0 A;  5HN7 A;  3WCH A;  5DJV F;  3N6K F;  4JXY A;  4DXJ A;  1UBX A;  5IK9 A;  4DHD A;  3LSN A;  4LFV F;  3V1V A;  5DJR F;  5B00 A;  3M01 A;  1VG3 A;  2F7M F;  3PDE A;  4LXW A;  1DGP A;  3KRO B;  4KQS A;  3IPI A;  4XQR F;  3CP6 A;  2F8Z F;  3NPR A;  2QIS A;  3KRA B;  5IL8 A;  4LIX A;  4LZ3 A;  2OPM A;  5E8K A;  3WCF A;  3KRF B;  1HX9 A;  3KRC A;  4GP2 A;  1N22 A;  4MC3 A;  1EZF A;  3S4J A;  2E8V A;  1KIZ A;  3SDU A;  4KVW A;  3ICK A;  3N0G A;  3PH7 A;  2ZCO A;  2E94 A;  1FPS A;  1VG4 A;  4KQ5 A;  3LLW A;  4NG6 A;  5IMP A;  2E91 A;  4EA2 A;  2E8X A;  3ICZ A;  4LFE A;  5B0L A;  3WCB A;  4KK2 A;  2Z4X A;  5ERM A;  3WEJ A;  2E8T A;  3EFQ A;  5ILK A;  3TC1 A;  1V4K A;  5IM1 A;  2FOR A;  3S9V A;  4LTV A;  5E8L A;  1WY0 A;  3WE9 A;  1HXC A;  1VG6 A;  1RTR A; 
#chains in the Genus database with same CATH homology
 3ZOU A;  5E8H A;  3PYB A;  5C05 A;  3G4D A;  1PS1 A;  4LUU A;  4DWG A;  1V4I A;  2Q58 A;  3ADZ A;  4LZC A;  4H5E F;  2Z4Y A;  3PKO A;  3ASX A;  4GP1 A;  5DHI A;  3LK5 A;  3G4F A;  3TFN A;  3DYH A;  3TFP A;  2AZK A;  5A0K A;  3MAV A;  4OMG A;  5IN8 A;  3N1W F;  3P8R A;  1UBW A;  3SDQ A;  4KVD A;  2OA6 A;  5ERO A;  1YJ4 A;  3M00 A;  5DIQ F;  5H9D A;  3VJ8 A;  2Z50 A;  3N3L F;  5B0I A;  3ZCD A;  3N49 F;  3AQC B;  5ILJ A;  1N1B A;  4E1E A;  2I19 A;  1ZW5 A;  4JYX A;  3WJK A;  2PS8 A;  4LOB A;  1YHL A;  2ZEV A;  3VJB A;  4EA1 A;  4F6V A;  3OAC A;  2Z4Z A;  5JV0 F;  3NRI A;  3ZMC A;  1N20 A;  3VJE A;  2E90 A;  2J5C A;  3M9U A;  5DW7 A;  2F8C F;  4KQU A;  3KB9 A;  2VF6 A;  1VG7 A;  4KUX A;  3OAB B;  4NUA A;  1HXG A;  4NKE A;  3N1V F;  3N3D A;  4LZ0 A;  4OMH A;  5HN8 A;  3KRO A;  3P41 A;  3LVS A;  3M0G A;  3ICM A;  2Z7I A;  3WCI A;  4KWD A;  3ACY A;  3KRF A;  4DWB A;  3LGZ B;  1HXA A;  3WJN A;  4K10 A;  2Z78 A;  4LPG F;  4LLT A;  2E4O A;  3LMD A;  4RXA A;  3VJC A;  2Z4V A;  3N45 F;  2P1C A;  3WJO A;  2Q9Z A;  5IKA A;  5B03 A;  4RXD A;  5ER8 A;  4JZB A;  3APZ A;  3WCJ A;  4KVI A;  3DYG A;  2ZEU A;  4NFI F;  2E8U A;  1N21 A;  2H8O A;  5DJP F;  4Q23 A;  2ZCS A;  5DZ2 A;  4E9U A;  4OKZ A;  2E95 A;  1JFA A;  3BNY A;  1YQ7 A;  4QPF A;  3NF2 A;  4LLS A;  4XQT F;  2FTZ A;  1DI1 A;  3KRC B;  3LZ9 A;  5A0I A;  3WCM A;  5CG6 A;  3WEG A;  3LJI A;  1JFG A;  5I1U A;  2AET A;  1YYS A;  3MZV A;  4DZW A;  4OKM A;  2PS5 A;  3SDT A;  3Q2Z A;  3W7F A;  2ONH A;  3UCA A;  4L2X F;  3WCD A;  4ZQ8 A;  3RBM A;  3P8L A;  2E93 A;  3SDR A;  1WL3 A;  3KBK A;  2AEK A;  1N24 A;  3EZ3 A;  3OAB A;  3VJD A;  2AZJ A;  4DEM F;  2F89 F;  1N1Z A;  5IL3 A;  1WL1 A;  1UBV A;  3WCE A;  3LDW A;  5DHK A;  3M02 A;  1RQI A;  1YYT A;  1HM7 A;  5IMN A;  4EA0 A;  4P0V A;  2E8W A;  5AFX A;  5IMI A;  5JV2 F;  4LA6 A;  4P0W A;  5EAU A;  2ZCR A;  3LGK A;  3Q30 A;  4H5D F;  5ILZ A;  2AZL A;  2RAH A;  3LG5 A;  3OYR A;  1YYR A;  3ZMB A;  3N46 F;  3EGT A;  3AE0 A;  2ONG A;  5AYP A;  3KRA A;  3ACW A;  2J1P A;  5IK6 A;  3WEI A;  3KRP B;  2ZCQ A;  1V4E A;  4KFA A;  4N1Z F;  3SAE A;  3OAC B;  2PS7 A;  5CG5 A;  4KKM A;  4LPH F;  1N23 A;  3N5H F;  3WEH A;  3WSB A;  5ILY A;  3RYW A;  2PS4 A;  3NPK A;  3AQ0 A;  2Z7H A;  2O1O A;  4KVY A;  1V4H A;  4KPD A;  3WEF A;  1YHM A;  4XQS F;  4F6X A;  3LEE A;  3P5P A;  4RYP A;  5EAS A;  4DI5 A;  4KPJ A;  3RYE A;  3QQV A;  2Q9Y A;  4QXS F;  5JV1 F;  3IBA A;  3CC9 A;  5AEL A;  5B0K A;  3WSA A;  5HNA A;  5B0M A;  3LOM A;  2Q80 A;  1YV5 A;  5ILD A;  3B7L A;  5A0J A;  3WCC A;  3VJA A;  1V4J A;  4RXC A;  4HD1 A;  4PVY F;  3RMG A;  3AQB B;  1WMW A;  5B02 A;  3WC9 A;  1WKZ A;  4OGU A;  1HM4 A;  3WEK A;  1WL0 A;  3ID0 A;  2OPN A;  5ILI A;  2DH4 A;  3WCG A;  3QKC A;  5AHU B;  4GA3 A;  2PS6 A;  4JZX A;  1YYU A;  1WL2 A;  3N0F A;  4NFK F;  3TS7 A;  5JA0 F;  3V1X A;  5ERN A;  4RXE A;  3ZL6 A;  4E9Z A;  3CKE A;  5HN9 A;  1YYQ A;  4MC8 A;  2AEL A;  4LTZ A;  4UMJ A;  1VG2 A;  2EWG A;  3BNX A;  5EAT A;  3N5J F;  2E92 A;  4NFJ F;  1KIY A;  3V66 A;  4F62 A;  1RQJ A;  3PYA A;  5ILH A;  3SDV A;  3TFV A;  2OGD A;  4MC0 A;  4FP4 A;  4P0X A;  1UBY A;  1YHK A;  4H5C F;  4FJQ A;  4JVJ F;  4PVX F;  3Q2Q A;  4LA5 A;  3ICN A;  4RNQ A;  3WCL A;  2ZY1 A;  4N9U A;  3KRP A;  3P5R A;  2Z52 A;  2J1O A;  3Q1O A;  4JXN A;  2Z4W A;  5DGS F;  2F92 F;  3WCA A;  4LFG A;  2F9K F;  5IVG A;  5DGM F;  5DGN F;  3VJ9 A;  5JUZ F;  4NKF A;  5IKH A;  3DYF A;  5KSX F;  4GAX A;  5B01 A;  2F94 F;  4WK5 A;  3ACX A;  5B0J A;  5IK0 A;  5HN7 A;  3WCH A;  5DJV F;  3N6K F;  4JXY A;  4DXJ A;  1UBX A;  5IK9 A;  4DHD A;  3LSN A;  4LFV F;  3V1V A;  5DJR F;  5B00 A;  3M01 A;  1VG3 A;  2F7M F;  3PDE A;  4LXW A;  1DGP A;  3KRO B;  4KQS A;  3IPI A;  4XQR F;  3CP6 A;  2F8Z F;  3NPR A;  2QIS A;  3KRA B;  5IL8 A;  4LIX A;  4LZ3 A;  2OPM A;  5E8K A;  3WCF A;  3KRF B;  1HX9 A;  3KRC A;  4GP2 A;  1N22 A;  4MC3 A;  1EZF A;  3S4J A;  2E8V A;  1KIZ A;  3SDU A;  4KVW A;  3ICK A;  3N0G A;  3PH7 A;  2ZCO A;  2E94 A;  1FPS A;  1VG4 A;  4KQ5 A;  3LLW A;  4NG6 A;  5IMP A;  2E91 A;  4EA2 A;  2E8X A;  3ICZ A;  4LFE A;  5B0L A;  3WCB A;  4KK2 A;  2Z4X A;  5ERM A;  3WEJ A;  2E8T A;  3EFQ A;  5ILK A;  3TC1 A;  1V4K A;  5IM1 A;  2FOR A;  3S9V A;  4LTV A;  5E8L A;  1WY0 A;  3WE9 A;  1HXC A;  1VG6 A;  1RTR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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