3WC9A

The complex structure of hssqs wtih ligand, fspp
Total Genus 135
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
135
sequence length
333
structure length
333
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 135
structure length 333
sequence length 333
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wc9A00
2E94A 3AQBB 3KROA 1WL0A 5EATA 3WCDA 2E8VA 1RTRA 4N9UA 3ICMA 3ID0A 3LEEA 4RYPA 3WJOA 3PH7A 4MC0A 3VJ9A 4UMJA 1HXCA 5DJPF 4LZCA 4KQUA 4DWBA 3AQ0A 2FTZA 3WCAA 3P8RA 2DH4A 5B0JA 3N5HF 4N1ZF 3P5RA 4XQRF 4RXCA 4DWGA 2OA6A 2J1PA 4JVJF 3QQVA 4LXWA 5DGNF 3LG5A 1WY0A 5IKHA 1KIYA 3QKCA 2OPNA 4NUAA 4JXYA 3LJIA 1JFGA 4LFGA 3SDVA 3WCLA 4OGUA 3DYHA 5ILKA 3VJEA 4FJQA 3P5PA 3S9VA 3WJNA 3WJKA 3P8LA 4QXSF 2AZJA 4KPDA 3M00A 4FP4A 5A0IA 4E1EA 3KRCB 1HXGA 3Q2ZA 4ZQ8A 2F8ZF 2E90A 1VG3A 5IL3A 4GA3A 4XQSF 4LPHF 3MZVA 1YYTA 3EFQA 5A0JA 4LLTA 3N46F 4KVWA 4H5CF 1UBWA 4NFIF 5A0KA 5HN9A 3V66A 2AETA 5CG6A 3TFVA 4KUXA 5IMNA 5IN8A 4WK5A 4E9UA 3V1XA 5ILYA 4RXAA 2AZLA 5DJRF 2F7MF 3WCCA 3CC9A 1UBXA 2E8UA 3SDUA 2ZY1A 4LA5A 3ZMCA 1EZFA 2AZKA 1VG6A 5DZ2A 3CP6A 1HX9A 3PDEA 3N0FA 4Q23A 3SDQA 4PVYF 3WCIA 3LGKA 5KSXF 5H9DA 1YQ7A 3ZCDA 4PVXF 2Z78A 2E92A 2F89F 2AELA 4KVYA 5ILDA 3RMGA 1DI1A 2QISA 1YHLA 4P0XA 1HM7A 3WCBA 4GP1A 1V4IA 2F94F 4NKFA 4JXNA 5AYPA 4DXJA 2E8WA 3VJBA 5DW7A 4L2XF 3Q2QA 3KRAB 3LK5A 1HXAA 5IMPA 3IPIA 4F6VA 5B0LA 5IVGA 5ERMA 5B0KA 3VJDA 5EASA 3LOMA 2E91A 5CG5A 5ERNA 3N5JF 1V4HA 2Z50A 2J1OA 4JZXA 1UBYA 4K10A 5IK9A 3KBKA 5ILJA 3P41A 4JYXA 1VG2A 3PYBA 3OABB 5B00A 2E93A 3WCGA 1N22A 3OACB 4LTVA 5JV0F 5JV2F 3ICZA 2P1CA 2Z4XA 1WL1A 2PS6A 3N1VF 1V4JA 1RQJA 2O1OA 2E95A 2F8CF 3BNYA 4LTZA 1N24A 5IK6A 2E8TA 3OYRA 5ILIA 3KRPB 5DHKA 3WEHA 5AELA 4OKZA 3NPKA 4LPGF 3M01A 3SDTA 3PYAA 5IMIA 3WE9A 5JV1F 1JFAA 3ACWA 1WKZA 3LDWA 3N49F 4LIXA 5E8KA 5HNAA 1WL3A 3Q1OA 4JZBA 3KRAA 4MC3A 2ZCRA 3WSAA 2AEKA 3WSBA 1N1ZA 5IK0A 1FPSA 3G4DA 3ZMBA 1N23A 2Z4ZA 3NF2A 3KRFB 4LLSA 2PS4A 2ZCQA 3N45F 1YYRA 3WEFA 4KWDA 2OPMA 4MC8A 2J5CA 3NRIA 4NFJF 2ONGA 5DGMF 3PKOA 4EA1A 3OACA 3ICNA 2Q58A 2Q9ZA 4NFKF 2Z52A 3LLWA 5C05A 4XQTF 5E8HA 3VJ8A 4OMGA 2EWGA 3N3DA 5JUZF 3M9UA 1YYQA 3W7FA 4QPFA 2E8XA 2ZEUA 5EROA 3S4JA 2F92F 3KRCA 4KPJA 1KIZA 3SAEA 3ASXA 4KFAA 4KVDA 3N1WF 5DHIA 5DIQF 3N0GA 5I1UA 1N21A 3WCEA 5IKAA 5AFXA 3TFPA 4EA0A 1YYUA 1ZW5A 4DI5A 1VG4A 3KRFA 3LZ9A 2Q80A 1YYSA 2ZCOA 2H8OA 2VF6A 3M0GA 3WCHA 2I19A 2ONHA 2Q9YA 4KK2A 5HN7A 4NKEA 3VJCA 1VG7A 2PS7A 4F62A 4LOBA 5ILZA 3BNXA 4KKMA 3WC9A 3WCJA 3AQCB 2OGDA 1V4KA 3SDRA 4LFEA 3TFNA 3EGTA 3N6KF 3MAVA 1YHKA 4RXDA 3WEGA 3N3LF 3B7LA 3WCFA 1N1BA 2Z7HA 3ACYA 4KQSA 3Q30A 4LA6A 3LGZB 2Z4WA 4DEMF 1YJ4A 3ICKA 5E8LA 3KB9A 4LZ0A 4RXEA 5DJVF 3M02A 1PS1A 5EAUA 2Z4YA 4OKMA 5ER8A 1RQIA 4P0VA 2FORA 3ZOUA 3ACXA 1YHMA 3KROB 5B0MA 5B02A 3ADZA 5AHUB 4KQ5A 1UBVA 3CKEA 1WMWA 5B03A 2Z4VA 5B0IA 3RYEA 3NPRA 3TC1A 4E9ZA 3EZ3A 4H5DF 1N20A 3UCAA 3VJAA 3OABA 4GP2A 4NG6A 3LMDA 4LZ3A 4RNQA 3APZA 1V4EA 2F9KF 3IBAA 1WL2A 5JA0F 2PS8A 4F6XA 3WEKA 4H5EF 5ILHA 4LFVF 4OMHA 1YV5A 4KVIA 3KRPA 4EA2A 4P0WA 3ZL6A 5HN8A 3DYFA 5IM1A 3WEIA 2ZCSA 3LSNA 5B01A 4DZWA 3LVSA 2ZEVA 3WCMA 2RAHA 2E4OA 2PS5A 3RBMA 3TS7A 1HM4A 4GAXA 3AE0A 4DHDA 3V1VA 5DGSF 3DYGA 3WEJA 4HD1A 3RYWA 2Z7IA 3G4FA 1DGPA 4LUUA 5IL8A
chains in the Genus database with same CATH superfamily
2E94A 3AQBB 3KROA 1WL0A 5EATA 3WCDA 2E8VA 1RTRA 4N9UA 3ICMA 3ID0A 3LEEA 4RYPA 3WJOA 3PH7A 4MC0A 3VJ9A 4UMJA 1HXCA 5DJPF 4LZCA 4KQUA 4DWBA 3AQ0A 2FTZA 3WCAA 3P8RA 2DH4A 5B0JA 3N5HF 4N1ZF 3P5RA 4XQRF 4RXCA 4DWGA 2OA6A 2J1PA 4JVJF 3QQVA 4LXWA 5DGNF 3LG5A 1WY0A 5IKHA 1KIYA 3QKCA 2OPNA 4NUAA 4JXYA 3LJIA 1JFGA 4LFGA 3SDVA 3WCLA 4OGUA 3DYHA 5ILKA 3VJEA 4FJQA 3P5PA 3S9VA 3WJNA 3WJKA 3P8LA 4QXSF 2AZJA 4KPDA 3M00A 4FP4A 5A0IA 4E1EA 3KRCB 1HXGA 3Q2ZA 4ZQ8A 2F8ZF 2E90A 1VG3A 5IL3A 4GA3A 4XQSF 4LPHF 3MZVA 1YYTA 3EFQA 5A0JA 4LLTA 3N46F 4KVWA 4H5CF 1UBWA 4NFIF 5A0KA 5HN9A 3V66A 2AETA 5CG6A 3TFVA 4KUXA 5IMNA 5IN8A 4WK5A 4E9UA 3V1XA 5ILYA 4RXAA 2AZLA 5DJRF 2F7MF 3WCCA 3CC9A 1UBXA 2E8UA 3SDUA 2ZY1A 4LA5A 3ZMCA 1EZFA 2AZKA 1VG6A 5DZ2A 3CP6A 1HX9A 3PDEA 3N0FA 4Q23A 3SDQA 4PVYF 3WCIA 3LGKA 5KSXF 5H9DA 1YQ7A 3ZCDA 4PVXF 2Z78A 2E92A 2F89F 2AELA 4KVYA 5ILDA 3RMGA 1DI1A 2QISA 1YHLA 4P0XA 1HM7A 3WCBA 4GP1A 1V4IA 2F94F 4NKFA 4JXNA 5AYPA 4DXJA 2E8WA 3VJBA 5DW7A 4L2XF 3Q2QA 3KRAB 3LK5A 1HXAA 5IMPA 3IPIA 4F6VA 5B0LA 5IVGA 5ERMA 5B0KA 3VJDA 5EASA 3LOMA 2E91A 5CG5A 5ERNA 3N5JF 1V4HA 2Z50A 2J1OA 4JZXA 1UBYA 4K10A 5IK9A 3KBKA 5ILJA 3P41A 4JYXA 1VG2A 3PYBA 3OABB 5B00A 2E93A 3WCGA 1N22A 3OACB 4LTVA 5JV0F 5JV2F 3ICZA 2P1CA 2Z4XA 1WL1A 2PS6A 3N1VF 1V4JA 1RQJA 2O1OA 2E95A 2F8CF 3BNYA 4LTZA 1N24A 5IK6A 2E8TA 3OYRA 5ILIA 3KRPB 5DHKA 3WEHA 5AELA 4OKZA 3NPKA 4LPGF 3M01A 3SDTA 3PYAA 5IMIA 3WE9A 5JV1F 1JFAA 3ACWA 1WKZA 3LDWA 3N49F 4LIXA 5E8KA 5HNAA 1WL3A 3Q1OA 4JZBA 3KRAA 4MC3A 2ZCRA 3WSAA 2AEKA 3WSBA 1N1ZA 5IK0A 1FPSA 3G4DA 3ZMBA 1N23A 2Z4ZA 3NF2A 3KRFB 4LLSA 2PS4A 2ZCQA 3N45F 1YYRA 3WEFA 4KWDA 2OPMA 4MC8A 2J5CA 3NRIA 4NFJF 2ONGA 5DGMF 3PKOA 4EA1A 3OACA 3ICNA 2Q58A 2Q9ZA 4NFKF 2Z52A 3LLWA 5C05A 4XQTF 5E8HA 3VJ8A 4OMGA 2EWGA 3N3DA 5JUZF 3M9UA 1YYQA 3W7FA 4QPFA 2E8XA 2ZEUA 5EROA 3S4JA 2F92F 3KRCA 4KPJA 1KIZA 3SAEA 3ASXA 4KFAA 4KVDA 3N1WF 5DHIA 5DIQF 3N0GA 5I1UA 1N21A 3WCEA 5IKAA 5AFXA 3TFPA 4EA0A 1YYUA 1ZW5A 4DI5A 1VG4A 3KRFA 3LZ9A 2Q80A 1YYSA 2ZCOA 2H8OA 2VF6A 3M0GA 3WCHA 2I19A 2ONHA 2Q9YA 4KK2A 5HN7A 4NKEA 3VJCA 1VG7A 2PS7A 4F62A 4LOBA 5ILZA 3BNXA 4KKMA 3WC9A 3WCJA 3AQCB 2OGDA 1V4KA 3SDRA 4LFEA 3TFNA 3EGTA 3N6KF 3MAVA 1YHKA 4RXDA 3WEGA 3N3LF 3B7LA 3WCFA 1N1BA 2Z7HA 3ACYA 4KQSA 3Q30A 4LA6A 3LGZB 2Z4WA 4DEMF 1YJ4A 3ICKA 5E8LA 3KB9A 4LZ0A 4RXEA 5DJVF 3M02A 1PS1A 5EAUA 2Z4YA 4OKMA 5ER8A 1RQIA 4P0VA 2FORA 3ZOUA 3ACXA 1YHMA 3KROB 5B0MA 5B02A 3ADZA 5AHUB 4KQ5A 1UBVA 3CKEA 1WMWA 5B03A 2Z4VA 5B0IA 3RYEA 3NPRA 3TC1A 4E9ZA 3EZ3A 4H5DF 1N20A 3UCAA 3VJAA 3OABA 4GP2A 4NG6A 3LMDA 4LZ3A 4RNQA 3APZA 1V4EA 2F9KF 3IBAA 1WL2A 5JA0F 2PS8A 4F6XA 3WEKA 4H5EF 5ILHA 4LFVF 4OMHA 1YV5A 4KVIA 3KRPA 4EA2A 4P0WA 3ZL6A 5HN8A 3DYFA 5IM1A 3WEIA 2ZCSA 3LSNA 5B01A 4DZWA 3LVSA 2ZEVA 3WCMA 2RAHA 2E4OA 2PS5A 3RBMA 3TS7A 1HM4A 4GAXA 3AE0A 4DHDA 3V1VA 5DGSF 3DYGA 3WEJA 4HD1A 3RYWA 2Z7IA 3G4FA 1DGPA 4LUUA 5IL8A
chains in the Genus database with same CATH topology
2E94A 3AQBB 3KROA 1WL0A 5EATA 3WCDA 2E8VA 1RTRA 4N9UA 3ICMA 3ID0A 3LEEA 4RYPA 3WJOA 3PH7A 4MC0A 3VJ9A 4UMJA 1HXCA 5DJPF 4LZCA 4KQUA 4DWBA 3AQ0A 2FTZA 3WCAA 3P8RA 2DH4A 5B0JA 3N5HF 4N1ZF 3P5RA 4XQRF 4RXCA 4DWGA 2OA6A 2J1PA 4JVJF 3QQVA 4LXWA 5DGNF 3LG5A 1WY0A 5IKHA 1KIYA 3QKCA 2OPNA 4NUAA 4JXYA 3LJIA 1JFGA 4LFGA 3SDVA 3WCLA 4OGUA 3DYHA 5ILKA 3VJEA 4FJQA 3P5PA 3S9VA 3WJNA 3WJKA 3P8LA 4QXSF 2AZJA 4KPDA 3M00A 4FP4A 5A0IA 4E1EA 3KRCB 1HXGA 3Q2ZA 4ZQ8A 2F8ZF 2E90A 1VG3A 5IL3A 4GA3A 4XQSF 4LPHF 3MZVA 1YYTA 3EFQA 5A0JA 4LLTA 3N46F 4KVWA 4H5CF 1UBWA 4NFIF 5A0KA 5HN9A 3V66A 2AETA 5CG6A 3TFVA 4KUXA 5IMNA 5IN8A 4WK5A 4E9UA 3V1XA 5ILYA 4RXAA 2AZLA 5DJRF 2F7MF 3WCCA 3CC9A 1UBXA 2E8UA 3SDUA 2ZY1A 4LA5A 3ZMCA 1EZFA 2AZKA 1VG6A 5DZ2A 3CP6A 1HX9A 3PDEA 3N0FA 4Q23A 3SDQA 4PVYF 3WCIA 3LGKA 5KSXF 5H9DA 1YQ7A 3ZCDA 4PVXF 2Z78A 2E92A 2F89F 2AELA 4KVYA 5ILDA 3RMGA 1DI1A 2QISA 1YHLA 4P0XA 1HM7A 3WCBA 4GP1A 1V4IA 2F94F 4NKFA 4JXNA 5AYPA 4DXJA 2E8WA 3VJBA 5DW7A 4L2XF 3Q2QA 3KRAB 3LK5A 1HXAA 5IMPA 3IPIA 4F6VA 5B0LA 5IVGA 5ERMA 5B0KA 3VJDA 5EASA 3LOMA 2E91A 5CG5A 5ERNA 3N5JF 1V4HA 2Z50A 2J1OA 4JZXA 1UBYA 4K10A 5IK9A 3KBKA 5ILJA 3P41A 4JYXA 1VG2A 3PYBA 3OABB 5B00A 2E93A 3WCGA 1N22A 3OACB 4LTVA 5JV0F 5JV2F 3ICZA 2P1CA 2Z4XA 1WL1A 2PS6A 3N1VF 1V4JA 1RQJA 2O1OA 2E95A 2F8CF 3BNYA 4LTZA 1N24A 5IK6A 2E8TA 3OYRA 5ILIA 3KRPB 5DHKA 3WEHA 5AELA 4OKZA 3NPKA 4LPGF 3M01A 3SDTA 3PYAA 5IMIA 3WE9A 5JV1F 1JFAA 3ACWA 1WKZA 3LDWA 3N49F 4LIXA 5E8KA 5HNAA 1WL3A 3Q1OA 4JZBA 3KRAA 4MC3A 2ZCRA 3WSAA 2AEKA 3WSBA 1N1ZA 5IK0A 1FPSA 3G4DA 3ZMBA 1N23A 2Z4ZA 3NF2A 3KRFB 4LLSA 2PS4A 2ZCQA 3N45F 1YYRA 3WEFA 4KWDA 2OPMA 4MC8A 2J5CA 3NRIA 4NFJF 2ONGA 5DGMF 3PKOA 4EA1A 3OACA 3ICNA 2Q58A 2Q9ZA 4NFKF 2Z52A 3LLWA 5C05A 4XQTF 5E8HA 3VJ8A 4OMGA 2EWGA 3N3DA 5JUZF 3M9UA 1YYQA 3W7FA 4QPFA 2E8XA 2ZEUA 5EROA 3S4JA 2F92F 3KRCA 4KPJA 1KIZA 3SAEA 3ASXA 4KFAA 4KVDA 3N1WF 5DHIA 5DIQF 3N0GA 5I1UA 1N21A 3WCEA 5IKAA 5AFXA 3TFPA 4EA0A 1YYUA 1ZW5A 4DI5A 1VG4A 3KRFA 3LZ9A 2Q80A 1YYSA 2ZCOA 2H8OA 2VF6A 3M0GA 3WCHA 2I19A 2ONHA 2Q9YA 4KK2A 5HN7A 4NKEA 3VJCA 1VG7A 2PS7A 4F62A 4LOBA 5ILZA 3BNXA 4KKMA 3WC9A 3WCJA 3AQCB 2OGDA 1V4KA 3SDRA 4LFEA 3TFNA 3EGTA 3N6KF 3MAVA 1YHKA 4RXDA 3WEGA 3N3LF 3B7LA 3WCFA 1N1BA 2Z7HA 3ACYA 4KQSA 3Q30A 4LA6A 3LGZB 2Z4WA 4DEMF 1YJ4A 3ICKA 5E8LA 3KB9A 4LZ0A 4RXEA 5DJVF 3M02A 1PS1A 5EAUA 2Z4YA 4OKMA 5ER8A 1RQIA 4P0VA 2FORA 3ZOUA 3ACXA 1YHMA 3KROB 5B0MA 5B02A 3ADZA 5AHUB 4KQ5A 1UBVA 3CKEA 1WMWA 5B03A 2Z4VA 5B0IA 3RYEA 3NPRA 3TC1A 4E9ZA 3EZ3A 4H5DF 1N20A 3UCAA 3VJAA 3OABA 4GP2A 4NG6A 3LMDA 4LZ3A 4RNQA 3APZA 1V4EA 2F9KF 3IBAA 1WL2A 5JA0F 2PS8A 4F6XA 3WEKA 4H5EF 5ILHA 4LFVF 4OMHA 1YV5A 4KVIA 3KRPA 4EA2A 4P0WA 3ZL6A 5HN8A 3DYFA 5IM1A 3WEIA 2ZCSA 3LSNA 5B01A 4DZWA 3LVSA 2ZEVA 3WCMA 2RAHA 2E4OA 2PS5A 3RBMA 3TS7A 1HM4A 4GAXA 3AE0A 4DHDA 3V1VA 5DGSF 3DYGA 3WEJA 4HD1A 3RYWA 2Z7IA 3G4FA 1DGPA 4LUUA 5IL8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E94 A;  3AQB B;  3KRO A;  1WL0 A;  5EAT A;  3WCD A;  2E8V A;  1RTR A;  4N9U A;  3ICM A;  3ID0 A;  3LEE A;  4RYP A;  3WJO A;  3PH7 A;  4MC0 A;  3VJ9 A;  4UMJ A;  1HXC A;  5DJP F;  4LZC A;  4KQU A;  4DWB A;  3AQ0 A;  2FTZ A;  3WCA A;  3P8R A;  2DH4 A;  5B0J A;  3N5H F;  4N1Z F;  3P5R A;  4XQR F;  4RXC A;  4DWG A;  2OA6 A;  2J1P A;  4JVJ F;  3QQV A;  4LXW A;  5DGN F;  3LG5 A;  1WY0 A;  5IKH A;  1KIY A;  3QKC A;  2OPN A;  4NUA A;  4JXY A;  3LJI A;  1JFG A;  4LFG A;  3SDV A;  3WCL A;  4OGU A;  3DYH A;  5ILK A;  3VJE A;  4FJQ A;  3P5P A;  3S9V A;  3WJN A;  3WJK A;  3P8L A;  4QXS F;  2AZJ A;  4KPD A;  3M00 A;  4FP4 A;  5A0I A;  4E1E A;  3KRC B;  1HXG A;  3Q2Z A;  4ZQ8 A;  2F8Z F;  2E90 A;  1VG3 A;  5IL3 A;  4GA3 A;  4XQS F;  4LPH F;  3MZV A;  1YYT A;  3EFQ A;  5A0J A;  4LLT A;  3N46 F;  4KVW A;  4H5C F;  1UBW A;  4NFI F;  5A0K A;  5HN9 A;  3V66 A;  2AET A;  5CG6 A;  3TFV A;  4KUX A;  5IMN A;  5IN8 A;  4WK5 A;  4E9U A;  3V1X A;  5ILY A;  4RXA A;  2AZL A;  5DJR F;  2F7M F;  3WCC A;  3CC9 A;  1UBX A;  2E8U A;  3SDU A;  2ZY1 A;  4LA5 A;  3ZMC A;  1EZF A;  2AZK A;  1VG6 A;  5DZ2 A;  3CP6 A;  1HX9 A;  3PDE A;  3N0F A;  4Q23 A;  3SDQ A;  4PVY F;  3WCI A;  3LGK A;  5KSX F;  5H9D A;  1YQ7 A;  3ZCD A;  4PVX F;  2Z78 A;  2E92 A;  2F89 F;  2AEL A;  4KVY A;  5ILD A;  3RMG A;  1DI1 A;  2QIS A;  1YHL A;  4P0X A;  1HM7 A;  3WCB A;  4GP1 A;  1V4I A;  2F94 F;  4NKF A;  4JXN A;  5AYP A;  4DXJ A;  2E8W A;  3VJB A;  5DW7 A;  4L2X F;  3Q2Q A;  3KRA B;  3LK5 A;  1HXA A;  5IMP A;  3IPI A;  4F6V A;  5B0L A;  5IVG A;  5ERM A;  5B0K A;  3VJD A;  5EAS A;  3LOM A;  2E91 A;  5CG5 A;  5ERN A;  3N5J F;  1V4H A;  2Z50 A;  2J1O A;  4JZX A;  1UBY A;  4K10 A;  5IK9 A;  3KBK A;  5ILJ A;  3P41 A;  4JYX A;  1VG2 A;  3PYB A;  3OAB B;  5B00 A;  2E93 A;  3WCG A;  1N22 A;  3OAC B;  4LTV A;  5JV0 F;  5JV2 F;  3ICZ A;  2P1C A;  2Z4X A;  1WL1 A;  2PS6 A;  3N1V F;  1V4J A;  1RQJ A;  2O1O A;  2E95 A;  2F8C F;  3BNY A;  4LTZ A;  1N24 A;  5IK6 A;  2E8T A;  3OYR A;  5ILI A;  3KRP B;  5DHK A;  3WEH A;  5AEL A;  4OKZ A;  3NPK A;  4LPG F;  3M01 A;  3SDT A;  3PYA A;  5IMI A;  3WE9 A;  5JV1 F;  1JFA A;  3ACW A;  1WKZ A;  3LDW A;  3N49 F;  4LIX A;  5E8K A;  5HNA A;  1WL3 A;  3Q1O A;  4JZB A;  3KRA A;  4MC3 A;  2ZCR A;  3WSA A;  2AEK A;  3WSB A;  1N1Z A;  5IK0 A;  1FPS A;  3G4D A;  3ZMB A;  1N23 A;  2Z4Z A;  3NF2 A;  3KRF B;  4LLS A;  2PS4 A;  2ZCQ A;  3N45 F;  1YYR A;  3WEF A;  4KWD A;  2OPM A;  4MC8 A;  2J5C A;  3NRI A;  4NFJ F;  2ONG A;  5DGM F;  3PKO A;  4EA1 A;  3OAC A;  3ICN A;  2Q58 A;  2Q9Z A;  4NFK F;  2Z52 A;  3LLW A;  5C05 A;  4XQT F;  5E8H A;  3VJ8 A;  4OMG A;  2EWG A;  3N3D A;  5JUZ F;  3M9U A;  1YYQ A;  3W7F A;  4QPF A;  2E8X A;  2ZEU A;  5ERO A;  3S4J A;  2F92 F;  3KRC A;  4KPJ A;  1KIZ A;  3SAE A;  3ASX A;  4KFA A;  4KVD A;  3N1W F;  5DHI A;  5DIQ F;  3N0G A;  5I1U A;  1N21 A;  3WCE A;  5IKA A;  5AFX A;  3TFP A;  4EA0 A;  1YYU A;  1ZW5 A;  4DI5 A;  1VG4 A;  3KRF A;  3LZ9 A;  2Q80 A;  1YYS A;  2ZCO A;  2H8O A;  2VF6 A;  3M0G A;  3WCH A;  2I19 A;  2ONH A;  2Q9Y A;  4KK2 A;  5HN7 A;  4NKE A;  3VJC A;  1VG7 A;  2PS7 A;  4F62 A;  4LOB A;  5ILZ A;  3BNX A;  4KKM A;  3WC9 A;  3WCJ A;  3AQC B;  2OGD A;  1V4K A;  3SDR A;  4LFE A;  3TFN A;  3EGT A;  3N6K F;  3MAV A;  1YHK A;  4RXD A;  3WEG A;  3N3L F;  3B7L A;  3WCF A;  1N1B A;  2Z7H A;  3ACY A;  4KQS A;  3Q30 A;  4LA6 A;  3LGZ B;  2Z4W A;  4DEM F;  1YJ4 A;  3ICK A;  5E8L A;  3KB9 A;  4LZ0 A;  4RXE A;  5DJV F;  3M02 A;  1PS1 A;  5EAU A;  2Z4Y A;  4OKM A;  5ER8 A;  1RQI A;  4P0V A;  2FOR A;  3ZOU A;  3ACX A;  1YHM A;  3KRO B;  5B0M A;  5B02 A;  3ADZ A;  5AHU B;  4KQ5 A;  1UBV A;  3CKE A;  1WMW A;  5B03 A;  2Z4V A;  5B0I A;  3RYE A;  3NPR A;  3TC1 A;  4E9Z A;  3EZ3 A;  4H5D F;  1N20 A;  3UCA A;  3VJA A;  3OAB A;  4GP2 A;  4NG6 A;  3LMD A;  4LZ3 A;  4RNQ A;  3APZ A;  1V4E A;  2F9K F;  3IBA A;  1WL2 A;  5JA0 F;  2PS8 A;  4F6X A;  3WEK A;  4H5E F;  5ILH A;  4LFV F;  4OMH A;  1YV5 A;  4KVI A;  3KRP A;  4EA2 A;  4P0W A;  3ZL6 A;  5HN8 A;  3DYF A;  5IM1 A;  3WEI A;  2ZCS A;  3LSN A;  5B01 A;  4DZW A;  3LVS A;  2ZEV A;  3WCM A;  2RAH A;  2E4O A;  2PS5 A;  3RBM A;  3TS7 A;  1HM4 A;  4GAX A;  3AE0 A;  4DHD A;  3V1V A;  5DGS F;  3DYG A;  3WEJ A;  4HD1 A;  3RYW A;  2Z7I A;  3G4F A;  1DGP A;  4LUU A;  5IL8 A; 
#chains in the Genus database with same CATH topology
 2E94 A;  3AQB B;  3KRO A;  1WL0 A;  5EAT A;  3WCD A;  2E8V A;  1RTR A;  4N9U A;  3ICM A;  3ID0 A;  3LEE A;  4RYP A;  3WJO A;  3PH7 A;  4MC0 A;  3VJ9 A;  4UMJ A;  1HXC A;  5DJP F;  4LZC A;  4KQU A;  4DWB A;  3AQ0 A;  2FTZ A;  3WCA A;  3P8R A;  2DH4 A;  5B0J A;  3N5H F;  4N1Z F;  3P5R A;  4XQR F;  4RXC A;  4DWG A;  2OA6 A;  2J1P A;  4JVJ F;  3QQV A;  4LXW A;  5DGN F;  3LG5 A;  1WY0 A;  5IKH A;  1KIY A;  3QKC A;  2OPN A;  4NUA A;  4JXY A;  3LJI A;  1JFG A;  4LFG A;  3SDV A;  3WCL A;  4OGU A;  3DYH A;  5ILK A;  3VJE A;  4FJQ A;  3P5P A;  3S9V A;  3WJN A;  3WJK A;  3P8L A;  4QXS F;  2AZJ A;  4KPD A;  3M00 A;  4FP4 A;  5A0I A;  4E1E A;  3KRC B;  1HXG A;  3Q2Z A;  4ZQ8 A;  2F8Z F;  2E90 A;  1VG3 A;  5IL3 A;  4GA3 A;  4XQS F;  4LPH F;  3MZV A;  1YYT A;  3EFQ A;  5A0J A;  4LLT A;  3N46 F;  4KVW A;  4H5C F;  1UBW A;  4NFI F;  5A0K A;  5HN9 A;  3V66 A;  2AET A;  5CG6 A;  3TFV A;  4KUX A;  5IMN A;  5IN8 A;  4WK5 A;  4E9U A;  3V1X A;  5ILY A;  4RXA A;  2AZL A;  5DJR F;  2F7M F;  3WCC A;  3CC9 A;  1UBX A;  2E8U A;  3SDU A;  2ZY1 A;  4LA5 A;  3ZMC A;  1EZF A;  2AZK A;  1VG6 A;  5DZ2 A;  3CP6 A;  1HX9 A;  3PDE A;  3N0F A;  4Q23 A;  3SDQ A;  4PVY F;  3WCI A;  3LGK A;  5KSX F;  5H9D A;  1YQ7 A;  3ZCD A;  4PVX F;  2Z78 A;  2E92 A;  2F89 F;  2AEL A;  4KVY A;  5ILD A;  3RMG A;  1DI1 A;  2QIS A;  1YHL A;  4P0X A;  1HM7 A;  3WCB A;  4GP1 A;  1V4I A;  2F94 F;  4NKF A;  4JXN A;  5AYP A;  4DXJ A;  2E8W A;  3VJB A;  5DW7 A;  4L2X F;  3Q2Q A;  3KRA B;  3LK5 A;  1HXA A;  5IMP A;  3IPI A;  4F6V A;  5B0L A;  5IVG A;  5ERM A;  5B0K A;  3VJD A;  5EAS A;  3LOM A;  2E91 A;  5CG5 A;  5ERN A;  3N5J F;  1V4H A;  2Z50 A;  2J1O A;  4JZX A;  1UBY A;  4K10 A;  5IK9 A;  3KBK A;  5ILJ A;  3P41 A;  4JYX A;  1VG2 A;  3PYB A;  3OAB B;  5B00 A;  2E93 A;  3WCG A;  1N22 A;  3OAC B;  4LTV A;  5JV0 F;  5JV2 F;  3ICZ A;  2P1C A;  2Z4X A;  1WL1 A;  2PS6 A;  3N1V F;  1V4J A;  1RQJ A;  2O1O A;  2E95 A;  2F8C F;  3BNY A;  4LTZ A;  1N24 A;  5IK6 A;  2E8T A;  3OYR A;  5ILI A;  3KRP B;  5DHK A;  3WEH A;  5AEL A;  4OKZ A;  3NPK A;  4LPG F;  3M01 A;  3SDT A;  3PYA A;  5IMI A;  3WE9 A;  5JV1 F;  1JFA A;  3ACW A;  1WKZ A;  3LDW A;  3N49 F;  4LIX A;  5E8K A;  5HNA A;  1WL3 A;  3Q1O A;  4JZB A;  3KRA A;  4MC3 A;  2ZCR A;  3WSA A;  2AEK A;  3WSB A;  1N1Z A;  5IK0 A;  1FPS A;  3G4D A;  3ZMB A;  1N23 A;  2Z4Z A;  3NF2 A;  3KRF B;  4LLS A;  2PS4 A;  2ZCQ A;  3N45 F;  1YYR A;  3WEF A;  4KWD A;  2OPM A;  4MC8 A;  2J5C A;  3NRI A;  4NFJ F;  2ONG A;  5DGM F;  3PKO A;  4EA1 A;  3OAC A;  3ICN A;  2Q58 A;  2Q9Z A;  4NFK F;  2Z52 A;  3LLW A;  5C05 A;  4XQT F;  5E8H A;  3VJ8 A;  4OMG A;  2EWG A;  3N3D A;  5JUZ F;  3M9U A;  1YYQ A;  3W7F A;  4QPF A;  2E8X A;  2ZEU A;  5ERO A;  3S4J A;  2F92 F;  3KRC A;  4KPJ A;  1KIZ A;  3SAE A;  3ASX A;  4KFA A;  4KVD A;  3N1W F;  5DHI A;  5DIQ F;  3N0G A;  5I1U A;  1N21 A;  3WCE A;  5IKA A;  5AFX A;  3TFP A;  4EA0 A;  1YYU A;  1ZW5 A;  4DI5 A;  1VG4 A;  3KRF A;  3LZ9 A;  2Q80 A;  1YYS A;  2ZCO A;  2H8O A;  2VF6 A;  3M0G A;  3WCH A;  2I19 A;  2ONH A;  2Q9Y A;  4KK2 A;  5HN7 A;  4NKE A;  3VJC A;  1VG7 A;  2PS7 A;  4F62 A;  4LOB A;  5ILZ A;  3BNX A;  4KKM A;  3WC9 A;  3WCJ A;  3AQC B;  2OGD A;  1V4K A;  3SDR A;  4LFE A;  3TFN A;  3EGT A;  3N6K F;  3MAV A;  1YHK A;  4RXD A;  3WEG A;  3N3L F;  3B7L A;  3WCF A;  1N1B A;  2Z7H A;  3ACY A;  4KQS A;  3Q30 A;  4LA6 A;  3LGZ B;  2Z4W A;  4DEM F;  1YJ4 A;  3ICK A;  5E8L A;  3KB9 A;  4LZ0 A;  4RXE A;  5DJV F;  3M02 A;  1PS1 A;  5EAU A;  2Z4Y A;  4OKM A;  5ER8 A;  1RQI A;  4P0V A;  2FOR A;  3ZOU A;  3ACX A;  1YHM A;  3KRO B;  5B0M A;  5B02 A;  3ADZ A;  5AHU B;  4KQ5 A;  1UBV A;  3CKE A;  1WMW A;  5B03 A;  2Z4V A;  5B0I A;  3RYE A;  3NPR A;  3TC1 A;  4E9Z A;  3EZ3 A;  4H5D F;  1N20 A;  3UCA A;  3VJA A;  3OAB A;  4GP2 A;  4NG6 A;  3LMD A;  4LZ3 A;  4RNQ A;  3APZ A;  1V4E A;  2F9K F;  3IBA A;  1WL2 A;  5JA0 F;  2PS8 A;  4F6X A;  3WEK A;  4H5E F;  5ILH A;  4LFV F;  4OMH A;  1YV5 A;  4KVI A;  3KRP A;  4EA2 A;  4P0W A;  3ZL6 A;  5HN8 A;  3DYF A;  5IM1 A;  3WEI A;  2ZCS A;  3LSN A;  5B01 A;  4DZW A;  3LVS A;  2ZEV A;  3WCM A;  2RAH A;  2E4O A;  2PS5 A;  3RBM A;  3TS7 A;  1HM4 A;  4GAX A;  3AE0 A;  4DHD A;  3V1V A;  5DGS F;  3DYG A;  3WEJ A;  4HD1 A;  3RYW A;  2Z7I A;  3G4F A;  1DGP A;  4LUU A;  5IL8 A; 
#chains in the Genus database with same CATH homology
 2E94 A;  3AQB B;  3KRO A;  1WL0 A;  5EAT A;  3WCD A;  2E8V A;  1RTR A;  4N9U A;  3ICM A;  3ID0 A;  3LEE A;  4RYP A;  3WJO A;  3PH7 A;  4MC0 A;  3VJ9 A;  4UMJ A;  1HXC A;  5DJP F;  4LZC A;  4KQU A;  4DWB A;  3AQ0 A;  2FTZ A;  3WCA A;  3P8R A;  2DH4 A;  5B0J A;  3N5H F;  4N1Z F;  3P5R A;  4XQR F;  4RXC A;  4DWG A;  2OA6 A;  2J1P A;  4JVJ F;  3QQV A;  4LXW A;  5DGN F;  3LG5 A;  1WY0 A;  5IKH A;  1KIY A;  3QKC A;  2OPN A;  4NUA A;  4JXY A;  3LJI A;  1JFG A;  4LFG A;  3SDV A;  3WCL A;  4OGU A;  3DYH A;  5ILK A;  3VJE A;  4FJQ A;  3P5P A;  3S9V A;  3WJN A;  3WJK A;  3P8L A;  4QXS F;  2AZJ A;  4KPD A;  3M00 A;  4FP4 A;  5A0I A;  4E1E A;  3KRC B;  1HXG A;  3Q2Z A;  4ZQ8 A;  2F8Z F;  2E90 A;  1VG3 A;  5IL3 A;  4GA3 A;  4XQS F;  4LPH F;  3MZV A;  1YYT A;  3EFQ A;  5A0J A;  4LLT A;  3N46 F;  4KVW A;  4H5C F;  1UBW A;  4NFI F;  5A0K A;  5HN9 A;  3V66 A;  2AET A;  5CG6 A;  3TFV A;  4KUX A;  5IMN A;  5IN8 A;  4WK5 A;  4E9U A;  3V1X A;  5ILY A;  4RXA A;  2AZL A;  5DJR F;  2F7M F;  3WCC A;  3CC9 A;  1UBX A;  2E8U A;  3SDU A;  2ZY1 A;  4LA5 A;  3ZMC A;  1EZF A;  2AZK A;  1VG6 A;  5DZ2 A;  3CP6 A;  1HX9 A;  3PDE A;  3N0F A;  4Q23 A;  3SDQ A;  4PVY F;  3WCI A;  3LGK A;  5KSX F;  5H9D A;  1YQ7 A;  3ZCD A;  4PVX F;  2Z78 A;  2E92 A;  2F89 F;  2AEL A;  4KVY A;  5ILD A;  3RMG A;  1DI1 A;  2QIS A;  1YHL A;  4P0X A;  1HM7 A;  3WCB A;  4GP1 A;  1V4I A;  2F94 F;  4NKF A;  4JXN A;  5AYP A;  4DXJ A;  2E8W A;  3VJB A;  5DW7 A;  4L2X F;  3Q2Q A;  3KRA B;  3LK5 A;  1HXA A;  5IMP A;  3IPI A;  4F6V A;  5B0L A;  5IVG A;  5ERM A;  5B0K A;  3VJD A;  5EAS A;  3LOM A;  2E91 A;  5CG5 A;  5ERN A;  3N5J F;  1V4H A;  2Z50 A;  2J1O A;  4JZX A;  1UBY A;  4K10 A;  5IK9 A;  3KBK A;  5ILJ A;  3P41 A;  4JYX A;  1VG2 A;  3PYB A;  3OAB B;  5B00 A;  2E93 A;  3WCG A;  1N22 A;  3OAC B;  4LTV A;  5JV0 F;  5JV2 F;  3ICZ A;  2P1C A;  2Z4X A;  1WL1 A;  2PS6 A;  3N1V F;  1V4J A;  1RQJ A;  2O1O A;  2E95 A;  2F8C F;  3BNY A;  4LTZ A;  1N24 A;  5IK6 A;  2E8T A;  3OYR A;  5ILI A;  3KRP B;  5DHK A;  3WEH A;  5AEL A;  4OKZ A;  3NPK A;  4LPG F;  3M01 A;  3SDT A;  3PYA A;  5IMI A;  3WE9 A;  5JV1 F;  1JFA A;  3ACW A;  1WKZ A;  3LDW A;  3N49 F;  4LIX A;  5E8K A;  5HNA A;  1WL3 A;  3Q1O A;  4JZB A;  3KRA A;  4MC3 A;  2ZCR A;  3WSA A;  2AEK A;  3WSB A;  1N1Z A;  5IK0 A;  1FPS A;  3G4D A;  3ZMB A;  1N23 A;  2Z4Z A;  3NF2 A;  3KRF B;  4LLS A;  2PS4 A;  2ZCQ A;  3N45 F;  1YYR A;  3WEF A;  4KWD A;  2OPM A;  4MC8 A;  2J5C A;  3NRI A;  4NFJ F;  2ONG A;  5DGM F;  3PKO A;  4EA1 A;  3OAC A;  3ICN A;  2Q58 A;  2Q9Z A;  4NFK F;  2Z52 A;  3LLW A;  5C05 A;  4XQT F;  5E8H A;  3VJ8 A;  4OMG A;  2EWG A;  3N3D A;  5JUZ F;  3M9U A;  1YYQ A;  3W7F A;  4QPF A;  2E8X A;  2ZEU A;  5ERO A;  3S4J A;  2F92 F;  3KRC A;  4KPJ A;  1KIZ A;  3SAE A;  3ASX A;  4KFA A;  4KVD A;  3N1W F;  5DHI A;  5DIQ F;  3N0G A;  5I1U A;  1N21 A;  3WCE A;  5IKA A;  5AFX A;  3TFP A;  4EA0 A;  1YYU A;  1ZW5 A;  4DI5 A;  1VG4 A;  3KRF A;  3LZ9 A;  2Q80 A;  1YYS A;  2ZCO A;  2H8O A;  2VF6 A;  3M0G A;  3WCH A;  2I19 A;  2ONH A;  2Q9Y A;  4KK2 A;  5HN7 A;  4NKE A;  3VJC A;  1VG7 A;  2PS7 A;  4F62 A;  4LOB A;  5ILZ A;  3BNX A;  4KKM A;  3WC9 A;  3WCJ A;  3AQC B;  2OGD A;  1V4K A;  3SDR A;  4LFE A;  3TFN A;  3EGT A;  3N6K F;  3MAV A;  1YHK A;  4RXD A;  3WEG A;  3N3L F;  3B7L A;  3WCF A;  1N1B A;  2Z7H A;  3ACY A;  4KQS A;  3Q30 A;  4LA6 A;  3LGZ B;  2Z4W A;  4DEM F;  1YJ4 A;  3ICK A;  5E8L A;  3KB9 A;  4LZ0 A;  4RXE A;  5DJV F;  3M02 A;  1PS1 A;  5EAU A;  2Z4Y A;  4OKM A;  5ER8 A;  1RQI A;  4P0V A;  2FOR A;  3ZOU A;  3ACX A;  1YHM A;  3KRO B;  5B0M A;  5B02 A;  3ADZ A;  5AHU B;  4KQ5 A;  1UBV A;  3CKE A;  1WMW A;  5B03 A;  2Z4V A;  5B0I A;  3RYE A;  3NPR A;  3TC1 A;  4E9Z A;  3EZ3 A;  4H5D F;  1N20 A;  3UCA A;  3VJA A;  3OAB A;  4GP2 A;  4NG6 A;  3LMD A;  4LZ3 A;  4RNQ A;  3APZ A;  1V4E A;  2F9K F;  3IBA A;  1WL2 A;  5JA0 F;  2PS8 A;  4F6X A;  3WEK A;  4H5E F;  5ILH A;  4LFV F;  4OMH A;  1YV5 A;  4KVI A;  3KRP A;  4EA2 A;  4P0W A;  3ZL6 A;  5HN8 A;  3DYF A;  5IM1 A;  3WEI A;  2ZCS A;  3LSN A;  5B01 A;  4DZW A;  3LVS A;  2ZEV A;  3WCM A;  2RAH A;  2E4O A;  2PS5 A;  3RBM A;  3TS7 A;  1HM4 A;  4GAX A;  3AE0 A;  4DHD A;  3V1V A;  5DGS F;  3DYG A;  3WEJ A;  4HD1 A;  3RYW A;  2Z7I A;  3G4F A;  1DGP A;  4LUU A;  5IL8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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