3WCDA

The complex structure of hssqs wtih ligand, wc-9
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 136
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wcdA00
3KRPA 3KROB 4DWBA 5HNAA 2ZCOA 3N49F 1V4JA 3EZ3A 4FJQA 4LZ3A 4MC3A 3ZCDA 5IMIA 3ZMBA 1UBVA 4UMJA 4N9UA 2ONHA 4GA3A 3WCGA 3Q2ZA 4P0VA 5E8LA 1KIZA 1N1BA 4Q23A 2PS4A 2E8WA 3CKEA 4OKMA 4FP4A 3ACYA 5HN7A 5AHUB 3V1VA 1RQIA 2E8XA 5A0JA 5E8HA 3AQ0A 3ADZA 3OABA 4E9ZA 1YYRA 5DJVF 3WCHA 2F94F 4KPDA 3Q2QA 4LA5A 5B02A 3TS7A 3B7LA 4KPJA 4MC0A 4F62A 5IVGA 5AELA 1DGPA 5IKHA 4LZCA 3P8LA 3QKCA 5DJPF 2F7MF 1N23A 3NPKA 3NPRA 3PYBA 4LTZA 3ICKA 1VG4A 4F6VA 2QISA 5DZ2A 3KRAA 2E92A 5DHIA 4JXYA 5B0MA 3WEIA 5DGNF 4OGUA 3KRCA 1HX9A 3KRFA 2FTZA 4KKMA 4XQRF 4OMHA 3NRIA 5A0KA 3LZ9A 2AZKA 2E90A 2ZEVA 3WCIA 3EGTA 4KWDA 2ZCQA 2ONGA 1YJ4A 3M01A 5IN8A 1V4IA 3VJ8A 1N20A 1N1ZA 1VG6A 3WE9A 3WCLA 5ILHA 3WC9A 3PYAA 2PS5A 4NKEA 5IM1A 4QXSF 3LOMA 5EATA 3WJKA 3N1WF 3RYWA 2E8VA 5KSXF 2F89F 3WEHA 3S4JA 1WY0A 4LLTA 2J1OA 3KBKA 3WCJA 2AZLA 3TC1A 5ILYA 4KQ5A 2AZJA 5DW7A 5E8KA 4PVYF 5AFXA 2E95A 3AE0A 2Z4XA 1WL0A 3VJAA 4LUUA 1WKZA 3S9VA 3WCEA 3LLWA 1JFAA 4EA1A 3MAVA 2E91A 5CG6A 1YHMA 1RQJA 4P0XA 3KRCB 3KRFB 4EA0A 5EAUA 1VG7A 2Z7IA 1DI1A 5IK9A 4DEMF 3P8RA 2Z4ZA 3WEFA 3RMGA 3LGZB 5A0IA 4LTVA 5B0JA 3ZL6A 5JA0F 1HXCA 3N6KF 3VJEA 2H8OA 4N1ZF 1VG3A 3P5RA 3IPIA 5IK0A 3ICNA 3WCAA 4LPGF 2E8TA 3LEEA 5IL8A 3TFVA 4LIXA 2F9KF 3APZA 4HD1A 1WL3A 4DI5A 4E1EA 4QPFA 2AETA 3DYHA 4MC8A 4GAXA 1YQ7A 3WJNA 4LA6A 4DXJA 3OACB 3ICMA 3M0GA 3SDUA 3MZVA 4ZQ8A 1VG2A 5IMPA 3G4DA 2O1OA 3KRPB 5H9DA 5DIQF 3M02A 4JZXA 3V1XA 3WEJA 2OA6A 2OPNA 3WCFA 3CP6A 4KVDA 3N0GA 5ER8A 3WCDA 3KROA 2VF6A 4GP2A 4LPHF 5IKAA 2ZCRA 5B00A 2Z7HA 2RAHA 4WK5A 4P0WA 3CC9A 4EA2A 2E94A 3BNYA 2E93A 3W7FA 3WCCA 5ILKA 1WL2A 3N5JF 4GP1A 3VJ9A 1N22A 3RBMA 4KQSA 4PVXF 4KK2A 1RTRA 2J5CA 3OABB 4JYXA 3WJOA 4RYPA 1KIYA 4DZWA 4RNQA 5EROA 4F6XA 3N3LF 3ACWA 3WCMA 3LDWA 3N46F 2DH4A 4E9UA 3Q1OA 3LVSA 1HXAA 1V4KA 4RXDA 5ILDA 4NKFA 1YHKA 2Z4WA 3LG5A 1WL1A 1PS1A 3LMDA 1V4EA 2AEKA 2J1PA 4NG6A 1HM7A 5IL3A 2EWGA 4OMGA 3P41A 1HXGA 3SDTA 4JXNA 2Z50A 2Q9YA 3KRAB 5DGMF 4KQUA 3SDVA 2F8ZF 3RYEA 2PS8A 2F92F 4NFKF 2OPMA 3IBAA 5DJRF 2ZY1A 4XQTF 4JZBA 1YV5A 5HN9A 5JUZF 2OGDA 3TFPA 4NUAA 2ZCSA 4JVJF 3N5HF 3N1VF 4LLSA 5EASA 5IMNA 3PKOA 3QQVA 1YYTA 4H5DF 5HN8A 3AQBB 2Z78A 4OKZA 4KVYA 3TFNA 3WCBA 3WEGA 1YHLA 1YYUA 4LZ0A 4RXAA 3M00A 3LGKA 4DHDA 2Z52A 1EZFA 5DHKA 5C05A 4KUXA 3PH7A 5IK6A 1JFGA 5JV1F 1ZW5A 4NFJF 4RXEA 3ACXA 3EFQA 3M9UA 1N21A 4H5CF 5ERNA 4LXWA 4NFIF 5ERMA 3ZOUA 3V66A 3SDRA 3LSNA 2E4OA 3SDQA 4KFAA 3WSBA 5CG5A 5ILJA 5ILZA 1UBXA 1V4HA 3UCAA 2Z4VA 2AELA 3P5PA 4DWGA 5B01A 4KVWA 4RXCA 5AYPA 3DYFA 3KB9A 3VJCA 4LFGA 4KVIA 5JV0F 3VJDA 2PS7A 5DGSF 5B03A 5B0KA 2PS6A 2Q9ZA 2Q58A 3N3DA 3OYRA 4XQSF 4LOBA 4LFVF 5ILIA 3ID0A 2ZEUA 3ASXA 4H5EF 5JV2F 3WSAA 4LFEA 2E8UA 3SAEA 3VJBA 2I19A 1UBWA 5B0IA 2F8CF 3N0FA 1HM4A 3WEKA 1UBYA 2Q80A 5B0LA 2Z4YA 4K10A 3LK5A 1YYSA 3G4FA 3ZMCA 2FORA 4L2XF 3NF2A 1N24A 3LJIA 3ICZA 1FPSA 3N45F 1YYQA 5I1UA 3Q30A 3BNXA 2P1CA 3OACA 3AQCB 3PDEA 1WMWA 3DYGA
chains in the Genus database with same CATH superfamily
3KRPA 3KROB 4DWBA 5HNAA 2ZCOA 3N49F 1V4JA 3EZ3A 4FJQA 4LZ3A 4MC3A 3ZCDA 5IMIA 3ZMBA 1UBVA 4UMJA 4N9UA 2ONHA 4GA3A 3WCGA 3Q2ZA 4P0VA 5E8LA 1KIZA 1N1BA 4Q23A 2PS4A 2E8WA 3CKEA 4OKMA 4FP4A 3ACYA 5HN7A 5AHUB 3V1VA 1RQIA 2E8XA 5A0JA 5E8HA 3AQ0A 3ADZA 3OABA 4E9ZA 1YYRA 5DJVF 3WCHA 2F94F 4KPDA 3Q2QA 4LA5A 5B02A 3TS7A 3B7LA 4KPJA 4MC0A 4F62A 5IVGA 5AELA 1DGPA 5IKHA 4LZCA 3P8LA 3QKCA 5DJPF 2F7MF 1N23A 3NPKA 3NPRA 3PYBA 4LTZA 3ICKA 1VG4A 4F6VA 2QISA 5DZ2A 3KRAA 2E92A 5DHIA 4JXYA 5B0MA 3WEIA 5DGNF 4OGUA 3KRCA 1HX9A 3KRFA 2FTZA 4KKMA 4XQRF 4OMHA 3NRIA 5A0KA 3LZ9A 2AZKA 2E90A 2ZEVA 3WCIA 3EGTA 4KWDA 2ZCQA 2ONGA 1YJ4A 3M01A 5IN8A 1V4IA 3VJ8A 1N20A 1N1ZA 1VG6A 3WE9A 3WCLA 5ILHA 3WC9A 3PYAA 2PS5A 4NKEA 5IM1A 4QXSF 3LOMA 5EATA 3WJKA 3N1WF 3RYWA 2E8VA 5KSXF 2F89F 3WEHA 3S4JA 1WY0A 4LLTA 2J1OA 3KBKA 3WCJA 2AZLA 3TC1A 5ILYA 4KQ5A 2AZJA 5DW7A 5E8KA 4PVYF 5AFXA 2E95A 3AE0A 2Z4XA 1WL0A 3VJAA 4LUUA 1WKZA 3S9VA 3WCEA 3LLWA 1JFAA 4EA1A 3MAVA 2E91A 5CG6A 1YHMA 1RQJA 4P0XA 3KRCB 3KRFB 4EA0A 5EAUA 1VG7A 2Z7IA 1DI1A 5IK9A 4DEMF 3P8RA 2Z4ZA 3WEFA 3RMGA 3LGZB 5A0IA 4LTVA 5B0JA 3ZL6A 5JA0F 1HXCA 3N6KF 3VJEA 2H8OA 4N1ZF 1VG3A 3P5RA 3IPIA 5IK0A 3ICNA 3WCAA 4LPGF 2E8TA 3LEEA 5IL8A 3TFVA 4LIXA 2F9KF 3APZA 4HD1A 1WL3A 4DI5A 4E1EA 4QPFA 2AETA 3DYHA 4MC8A 4GAXA 1YQ7A 3WJNA 4LA6A 4DXJA 3OACB 3ICMA 3M0GA 3SDUA 3MZVA 4ZQ8A 1VG2A 5IMPA 3G4DA 2O1OA 3KRPB 5H9DA 5DIQF 3M02A 4JZXA 3V1XA 3WEJA 2OA6A 2OPNA 3WCFA 3CP6A 4KVDA 3N0GA 5ER8A 3WCDA 3KROA 2VF6A 4GP2A 4LPHF 5IKAA 2ZCRA 5B00A 2Z7HA 2RAHA 4WK5A 4P0WA 3CC9A 4EA2A 2E94A 3BNYA 2E93A 3W7FA 3WCCA 5ILKA 1WL2A 3N5JF 4GP1A 3VJ9A 1N22A 3RBMA 4KQSA 4PVXF 4KK2A 1RTRA 2J5CA 3OABB 4JYXA 3WJOA 4RYPA 1KIYA 4DZWA 4RNQA 5EROA 4F6XA 3N3LF 3ACWA 3WCMA 3LDWA 3N46F 2DH4A 4E9UA 3Q1OA 3LVSA 1HXAA 1V4KA 4RXDA 5ILDA 4NKFA 1YHKA 2Z4WA 3LG5A 1WL1A 1PS1A 3LMDA 1V4EA 2AEKA 2J1PA 4NG6A 1HM7A 5IL3A 2EWGA 4OMGA 3P41A 1HXGA 3SDTA 4JXNA 2Z50A 2Q9YA 3KRAB 5DGMF 4KQUA 3SDVA 2F8ZF 3RYEA 2PS8A 2F92F 4NFKF 2OPMA 3IBAA 5DJRF 2ZY1A 4XQTF 4JZBA 1YV5A 5HN9A 5JUZF 2OGDA 3TFPA 4NUAA 2ZCSA 4JVJF 3N5HF 3N1VF 4LLSA 5EASA 5IMNA 3PKOA 3QQVA 1YYTA 4H5DF 5HN8A 3AQBB 2Z78A 4OKZA 4KVYA 3TFNA 3WCBA 3WEGA 1YHLA 1YYUA 4LZ0A 4RXAA 3M00A 3LGKA 4DHDA 2Z52A 1EZFA 5DHKA 5C05A 4KUXA 3PH7A 5IK6A 1JFGA 5JV1F 1ZW5A 4NFJF 4RXEA 3ACXA 3EFQA 3M9UA 1N21A 4H5CF 5ERNA 4LXWA 4NFIF 5ERMA 3ZOUA 3V66A 3SDRA 3LSNA 2E4OA 3SDQA 4KFAA 3WSBA 5CG5A 5ILJA 5ILZA 1UBXA 1V4HA 3UCAA 2Z4VA 2AELA 3P5PA 4DWGA 5B01A 4KVWA 4RXCA 5AYPA 3DYFA 3KB9A 3VJCA 4LFGA 4KVIA 5JV0F 3VJDA 2PS7A 5DGSF 5B03A 5B0KA 2PS6A 2Q9ZA 2Q58A 3N3DA 3OYRA 4XQSF 4LOBA 4LFVF 5ILIA 3ID0A 2ZEUA 3ASXA 4H5EF 5JV2F 3WSAA 4LFEA 2E8UA 3SAEA 3VJBA 2I19A 1UBWA 5B0IA 2F8CF 3N0FA 1HM4A 3WEKA 1UBYA 2Q80A 5B0LA 2Z4YA 4K10A 3LK5A 1YYSA 3G4FA 3ZMCA 2FORA 4L2XF 3NF2A 1N24A 3LJIA 3ICZA 1FPSA 3N45F 1YYQA 5I1UA 3Q30A 3BNXA 2P1CA 3OACA 3AQCB 3PDEA 1WMWA 3DYGA
chains in the Genus database with same CATH topology
3KRPA 3KROB 4DWBA 5HNAA 2ZCOA 3N49F 1V4JA 3EZ3A 4FJQA 4LZ3A 4MC3A 3ZCDA 5IMIA 3ZMBA 1UBVA 4UMJA 4N9UA 2ONHA 4GA3A 3WCGA 3Q2ZA 4P0VA 5E8LA 1KIZA 1N1BA 4Q23A 2PS4A 2E8WA 3CKEA 4OKMA 4FP4A 3ACYA 5HN7A 5AHUB 3V1VA 1RQIA 2E8XA 5A0JA 5E8HA 3AQ0A 3ADZA 3OABA 4E9ZA 1YYRA 5DJVF 3WCHA 2F94F 4KPDA 3Q2QA 4LA5A 5B02A 3TS7A 3B7LA 4KPJA 4MC0A 4F62A 5IVGA 5AELA 1DGPA 5IKHA 4LZCA 3P8LA 3QKCA 5DJPF 2F7MF 1N23A 3NPKA 3NPRA 3PYBA 4LTZA 3ICKA 1VG4A 4F6VA 2QISA 5DZ2A 3KRAA 2E92A 5DHIA 4JXYA 5B0MA 3WEIA 5DGNF 4OGUA 3KRCA 1HX9A 3KRFA 2FTZA 4KKMA 4XQRF 4OMHA 3NRIA 5A0KA 3LZ9A 2AZKA 2E90A 2ZEVA 3WCIA 3EGTA 4KWDA 2ZCQA 2ONGA 1YJ4A 3M01A 5IN8A 1V4IA 3VJ8A 1N20A 1N1ZA 1VG6A 3WE9A 3WCLA 5ILHA 3WC9A 3PYAA 2PS5A 4NKEA 5IM1A 4QXSF 3LOMA 5EATA 3WJKA 3N1WF 3RYWA 2E8VA 5KSXF 2F89F 3WEHA 3S4JA 1WY0A 4LLTA 2J1OA 3KBKA 3WCJA 2AZLA 3TC1A 5ILYA 4KQ5A 2AZJA 5DW7A 5E8KA 4PVYF 5AFXA 2E95A 3AE0A 2Z4XA 1WL0A 3VJAA 4LUUA 1WKZA 3S9VA 3WCEA 3LLWA 1JFAA 4EA1A 3MAVA 2E91A 5CG6A 1YHMA 1RQJA 4P0XA 3KRCB 3KRFB 4EA0A 5EAUA 1VG7A 2Z7IA 1DI1A 5IK9A 4DEMF 3P8RA 2Z4ZA 3WEFA 3RMGA 3LGZB 5A0IA 4LTVA 5B0JA 3ZL6A 5JA0F 1HXCA 3N6KF 3VJEA 2H8OA 4N1ZF 1VG3A 3P5RA 3IPIA 5IK0A 3ICNA 3WCAA 4LPGF 2E8TA 3LEEA 5IL8A 3TFVA 4LIXA 2F9KF 3APZA 4HD1A 1WL3A 4DI5A 4E1EA 4QPFA 2AETA 3DYHA 4MC8A 4GAXA 1YQ7A 3WJNA 4LA6A 4DXJA 3OACB 3ICMA 3M0GA 3SDUA 3MZVA 4ZQ8A 1VG2A 5IMPA 3G4DA 2O1OA 3KRPB 5H9DA 5DIQF 3M02A 4JZXA 3V1XA 3WEJA 2OA6A 2OPNA 3WCFA 3CP6A 4KVDA 3N0GA 5ER8A 3WCDA 3KROA 2VF6A 4GP2A 4LPHF 5IKAA 2ZCRA 5B00A 2Z7HA 2RAHA 4WK5A 4P0WA 3CC9A 4EA2A 2E94A 3BNYA 2E93A 3W7FA 3WCCA 5ILKA 1WL2A 3N5JF 4GP1A 3VJ9A 1N22A 3RBMA 4KQSA 4PVXF 4KK2A 1RTRA 2J5CA 3OABB 4JYXA 3WJOA 4RYPA 1KIYA 4DZWA 4RNQA 5EROA 4F6XA 3N3LF 3ACWA 3WCMA 3LDWA 3N46F 2DH4A 4E9UA 3Q1OA 3LVSA 1HXAA 1V4KA 4RXDA 5ILDA 4NKFA 1YHKA 2Z4WA 3LG5A 1WL1A 1PS1A 3LMDA 1V4EA 2AEKA 2J1PA 4NG6A 1HM7A 5IL3A 2EWGA 4OMGA 3P41A 1HXGA 3SDTA 4JXNA 2Z50A 2Q9YA 3KRAB 5DGMF 4KQUA 3SDVA 2F8ZF 3RYEA 2PS8A 2F92F 4NFKF 2OPMA 3IBAA 5DJRF 2ZY1A 4XQTF 4JZBA 1YV5A 5HN9A 5JUZF 2OGDA 3TFPA 4NUAA 2ZCSA 4JVJF 3N5HF 3N1VF 4LLSA 5EASA 5IMNA 3PKOA 3QQVA 1YYTA 4H5DF 5HN8A 3AQBB 2Z78A 4OKZA 4KVYA 3TFNA 3WCBA 3WEGA 1YHLA 1YYUA 4LZ0A 4RXAA 3M00A 3LGKA 4DHDA 2Z52A 1EZFA 5DHKA 5C05A 4KUXA 3PH7A 5IK6A 1JFGA 5JV1F 1ZW5A 4NFJF 4RXEA 3ACXA 3EFQA 3M9UA 1N21A 4H5CF 5ERNA 4LXWA 4NFIF 5ERMA 3ZOUA 3V66A 3SDRA 3LSNA 2E4OA 3SDQA 4KFAA 3WSBA 5CG5A 5ILJA 5ILZA 1UBXA 1V4HA 3UCAA 2Z4VA 2AELA 3P5PA 4DWGA 5B01A 4KVWA 4RXCA 5AYPA 3DYFA 3KB9A 3VJCA 4LFGA 4KVIA 5JV0F 3VJDA 2PS7A 5DGSF 5B03A 5B0KA 2PS6A 2Q9ZA 2Q58A 3N3DA 3OYRA 4XQSF 4LOBA 4LFVF 5ILIA 3ID0A 2ZEUA 3ASXA 4H5EF 5JV2F 3WSAA 4LFEA 2E8UA 3SAEA 3VJBA 2I19A 1UBWA 5B0IA 2F8CF 3N0FA 1HM4A 3WEKA 1UBYA 2Q80A 5B0LA 2Z4YA 4K10A 3LK5A 1YYSA 3G4FA 3ZMCA 2FORA 4L2XF 3NF2A 1N24A 3LJIA 3ICZA 1FPSA 3N45F 1YYQA 5I1UA 3Q30A 3BNXA 2P1CA 3OACA 3AQCB 3PDEA 1WMWA 3DYGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRP A;  3KRO B;  4DWB A;  5HNA A;  2ZCO A;  3N49 F;  1V4J A;  3EZ3 A;  4FJQ A;  4LZ3 A;  4MC3 A;  3ZCD A;  5IMI A;  3ZMB A;  1UBV A;  4UMJ A;  4N9U A;  2ONH A;  4GA3 A;  3WCG A;  3Q2Z A;  4P0V A;  5E8L A;  1KIZ A;  1N1B A;  4Q23 A;  2PS4 A;  2E8W A;  3CKE A;  4OKM A;  4FP4 A;  3ACY A;  5HN7 A;  5AHU B;  3V1V A;  1RQI A;  2E8X A;  5A0J A;  5E8H A;  3AQ0 A;  3ADZ A;  3OAB A;  4E9Z A;  1YYR A;  5DJV F;  3WCH A;  2F94 F;  4KPD A;  3Q2Q A;  4LA5 A;  5B02 A;  3TS7 A;  3B7L A;  4KPJ A;  4MC0 A;  4F62 A;  5IVG A;  5AEL A;  1DGP A;  5IKH A;  4LZC A;  3P8L A;  3QKC A;  5DJP F;  2F7M F;  1N23 A;  3NPK A;  3NPR A;  3PYB A;  4LTZ A;  3ICK A;  1VG4 A;  4F6V A;  2QIS A;  5DZ2 A;  3KRA A;  2E92 A;  5DHI A;  4JXY A;  5B0M A;  3WEI A;  5DGN F;  4OGU A;  3KRC A;  1HX9 A;  3KRF A;  2FTZ A;  4KKM A;  4XQR F;  4OMH A;  3NRI A;  5A0K A;  3LZ9 A;  2AZK A;  2E90 A;  2ZEV A;  3WCI A;  3EGT A;  4KWD A;  2ZCQ A;  2ONG A;  1YJ4 A;  3M01 A;  5IN8 A;  1V4I A;  3VJ8 A;  1N20 A;  1N1Z A;  1VG6 A;  3WE9 A;  3WCL A;  5ILH A;  3WC9 A;  3PYA A;  2PS5 A;  4NKE A;  5IM1 A;  4QXS F;  3LOM A;  5EAT A;  3WJK A;  3N1W F;  3RYW A;  2E8V A;  5KSX F;  2F89 F;  3WEH A;  3S4J A;  1WY0 A;  4LLT A;  2J1O A;  3KBK A;  3WCJ A;  2AZL A;  3TC1 A;  5ILY A;  4KQ5 A;  2AZJ A;  5DW7 A;  5E8K A;  4PVY F;  5AFX A;  2E95 A;  3AE0 A;  2Z4X A;  1WL0 A;  3VJA A;  4LUU A;  1WKZ A;  3S9V A;  3WCE A;  3LLW A;  1JFA A;  4EA1 A;  3MAV A;  2E91 A;  5CG6 A;  1YHM A;  1RQJ A;  4P0X A;  3KRC B;  3KRF B;  4EA0 A;  5EAU A;  1VG7 A;  2Z7I A;  1DI1 A;  5IK9 A;  4DEM F;  3P8R A;  2Z4Z A;  3WEF A;  3RMG A;  3LGZ B;  5A0I A;  4LTV A;  5B0J A;  3ZL6 A;  5JA0 F;  1HXC A;  3N6K F;  3VJE A;  2H8O A;  4N1Z F;  1VG3 A;  3P5R A;  3IPI A;  5IK0 A;  3ICN A;  3WCA A;  4LPG F;  2E8T A;  3LEE A;  5IL8 A;  3TFV A;  4LIX A;  2F9K F;  3APZ A;  4HD1 A;  1WL3 A;  4DI5 A;  4E1E A;  4QPF A;  2AET A;  3DYH A;  4MC8 A;  4GAX A;  1YQ7 A;  3WJN A;  4LA6 A;  4DXJ A;  3OAC B;  3ICM A;  3M0G A;  3SDU A;  3MZV A;  4ZQ8 A;  1VG2 A;  5IMP A;  3G4D A;  2O1O A;  3KRP B;  5H9D A;  5DIQ F;  3M02 A;  4JZX A;  3V1X A;  3WEJ A;  2OA6 A;  2OPN A;  3WCF A;  3CP6 A;  4KVD A;  3N0G A;  5ER8 A;  3WCD A;  3KRO A;  2VF6 A;  4GP2 A;  4LPH F;  5IKA A;  2ZCR A;  5B00 A;  2Z7H A;  2RAH A;  4WK5 A;  4P0W A;  3CC9 A;  4EA2 A;  2E94 A;  3BNY A;  2E93 A;  3W7F A;  3WCC A;  5ILK A;  1WL2 A;  3N5J F;  4GP1 A;  3VJ9 A;  1N22 A;  3RBM A;  4KQS A;  4PVX F;  4KK2 A;  1RTR A;  2J5C A;  3OAB B;  4JYX A;  3WJO A;  4RYP A;  1KIY A;  4DZW A;  4RNQ A;  5ERO A;  4F6X A;  3N3L F;  3ACW A;  3WCM A;  3LDW A;  3N46 F;  2DH4 A;  4E9U A;  3Q1O A;  3LVS A;  1HXA A;  1V4K A;  4RXD A;  5ILD A;  4NKF A;  1YHK A;  2Z4W A;  3LG5 A;  1WL1 A;  1PS1 A;  3LMD A;  1V4E A;  2AEK A;  2J1P A;  4NG6 A;  1HM7 A;  5IL3 A;  2EWG A;  4OMG A;  3P41 A;  1HXG A;  3SDT A;  4JXN A;  2Z50 A;  2Q9Y A;  3KRA B;  5DGM F;  4KQU A;  3SDV A;  2F8Z F;  3RYE A;  2PS8 A;  2F92 F;  4NFK F;  2OPM A;  3IBA A;  5DJR F;  2ZY1 A;  4XQT F;  4JZB A;  1YV5 A;  5HN9 A;  5JUZ F;  2OGD A;  3TFP A;  4NUA A;  2ZCS A;  4JVJ F;  3N5H F;  3N1V F;  4LLS A;  5EAS A;  5IMN A;  3PKO A;  3QQV A;  1YYT A;  4H5D F;  5HN8 A;  3AQB B;  2Z78 A;  4OKZ A;  4KVY A;  3TFN A;  3WCB A;  3WEG A;  1YHL A;  1YYU A;  4LZ0 A;  4RXA A;  3M00 A;  3LGK A;  4DHD A;  2Z52 A;  1EZF A;  5DHK A;  5C05 A;  4KUX A;  3PH7 A;  5IK6 A;  1JFG A;  5JV1 F;  1ZW5 A;  4NFJ F;  4RXE A;  3ACX A;  3EFQ A;  3M9U A;  1N21 A;  4H5C F;  5ERN A;  4LXW A;  4NFI F;  5ERM A;  3ZOU A;  3V66 A;  3SDR A;  3LSN A;  2E4O A;  3SDQ A;  4KFA A;  3WSB A;  5CG5 A;  5ILJ A;  5ILZ A;  1UBX A;  1V4H A;  3UCA A;  2Z4V A;  2AEL A;  3P5P A;  4DWG A;  5B01 A;  4KVW A;  4RXC A;  5AYP A;  3DYF A;  3KB9 A;  3VJC A;  4LFG A;  4KVI A;  5JV0 F;  3VJD A;  2PS7 A;  5DGS F;  5B03 A;  5B0K A;  2PS6 A;  2Q9Z A;  2Q58 A;  3N3D A;  3OYR A;  4XQS F;  4LOB A;  4LFV F;  5ILI A;  3ID0 A;  2ZEU A;  3ASX A;  4H5E F;  5JV2 F;  3WSA A;  4LFE A;  2E8U A;  3SAE A;  3VJB A;  2I19 A;  1UBW A;  5B0I A;  2F8C F;  3N0F A;  1HM4 A;  3WEK A;  1UBY A;  2Q80 A;  5B0L A;  2Z4Y A;  4K10 A;  3LK5 A;  1YYS A;  3G4F A;  3ZMC A;  2FOR A;  4L2X F;  3NF2 A;  1N24 A;  3LJI A;  3ICZ A;  1FPS A;  3N45 F;  1YYQ A;  5I1U A;  3Q30 A;  3BNX A;  2P1C A;  3OAC A;  3AQC B;  3PDE A;  1WMW A;  3DYG A; 
#chains in the Genus database with same CATH topology
 3KRP A;  3KRO B;  4DWB A;  5HNA A;  2ZCO A;  3N49 F;  1V4J A;  3EZ3 A;  4FJQ A;  4LZ3 A;  4MC3 A;  3ZCD A;  5IMI A;  3ZMB A;  1UBV A;  4UMJ A;  4N9U A;  2ONH A;  4GA3 A;  3WCG A;  3Q2Z A;  4P0V A;  5E8L A;  1KIZ A;  1N1B A;  4Q23 A;  2PS4 A;  2E8W A;  3CKE A;  4OKM A;  4FP4 A;  3ACY A;  5HN7 A;  5AHU B;  3V1V A;  1RQI A;  2E8X A;  5A0J A;  5E8H A;  3AQ0 A;  3ADZ A;  3OAB A;  4E9Z A;  1YYR A;  5DJV F;  3WCH A;  2F94 F;  4KPD A;  3Q2Q A;  4LA5 A;  5B02 A;  3TS7 A;  3B7L A;  4KPJ A;  4MC0 A;  4F62 A;  5IVG A;  5AEL A;  1DGP A;  5IKH A;  4LZC A;  3P8L A;  3QKC A;  5DJP F;  2F7M F;  1N23 A;  3NPK A;  3NPR A;  3PYB A;  4LTZ A;  3ICK A;  1VG4 A;  4F6V A;  2QIS A;  5DZ2 A;  3KRA A;  2E92 A;  5DHI A;  4JXY A;  5B0M A;  3WEI A;  5DGN F;  4OGU A;  3KRC A;  1HX9 A;  3KRF A;  2FTZ A;  4KKM A;  4XQR F;  4OMH A;  3NRI A;  5A0K A;  3LZ9 A;  2AZK A;  2E90 A;  2ZEV A;  3WCI A;  3EGT A;  4KWD A;  2ZCQ A;  2ONG A;  1YJ4 A;  3M01 A;  5IN8 A;  1V4I A;  3VJ8 A;  1N20 A;  1N1Z A;  1VG6 A;  3WE9 A;  3WCL A;  5ILH A;  3WC9 A;  3PYA A;  2PS5 A;  4NKE A;  5IM1 A;  4QXS F;  3LOM A;  5EAT A;  3WJK A;  3N1W F;  3RYW A;  2E8V A;  5KSX F;  2F89 F;  3WEH A;  3S4J A;  1WY0 A;  4LLT A;  2J1O A;  3KBK A;  3WCJ A;  2AZL A;  3TC1 A;  5ILY A;  4KQ5 A;  2AZJ A;  5DW7 A;  5E8K A;  4PVY F;  5AFX A;  2E95 A;  3AE0 A;  2Z4X A;  1WL0 A;  3VJA A;  4LUU A;  1WKZ A;  3S9V A;  3WCE A;  3LLW A;  1JFA A;  4EA1 A;  3MAV A;  2E91 A;  5CG6 A;  1YHM A;  1RQJ A;  4P0X A;  3KRC B;  3KRF B;  4EA0 A;  5EAU A;  1VG7 A;  2Z7I A;  1DI1 A;  5IK9 A;  4DEM F;  3P8R A;  2Z4Z A;  3WEF A;  3RMG A;  3LGZ B;  5A0I A;  4LTV A;  5B0J A;  3ZL6 A;  5JA0 F;  1HXC A;  3N6K F;  3VJE A;  2H8O A;  4N1Z F;  1VG3 A;  3P5R A;  3IPI A;  5IK0 A;  3ICN A;  3WCA A;  4LPG F;  2E8T A;  3LEE A;  5IL8 A;  3TFV A;  4LIX A;  2F9K F;  3APZ A;  4HD1 A;  1WL3 A;  4DI5 A;  4E1E A;  4QPF A;  2AET A;  3DYH A;  4MC8 A;  4GAX A;  1YQ7 A;  3WJN A;  4LA6 A;  4DXJ A;  3OAC B;  3ICM A;  3M0G A;  3SDU A;  3MZV A;  4ZQ8 A;  1VG2 A;  5IMP A;  3G4D A;  2O1O A;  3KRP B;  5H9D A;  5DIQ F;  3M02 A;  4JZX A;  3V1X A;  3WEJ A;  2OA6 A;  2OPN A;  3WCF A;  3CP6 A;  4KVD A;  3N0G A;  5ER8 A;  3WCD A;  3KRO A;  2VF6 A;  4GP2 A;  4LPH F;  5IKA A;  2ZCR A;  5B00 A;  2Z7H A;  2RAH A;  4WK5 A;  4P0W A;  3CC9 A;  4EA2 A;  2E94 A;  3BNY A;  2E93 A;  3W7F A;  3WCC A;  5ILK A;  1WL2 A;  3N5J F;  4GP1 A;  3VJ9 A;  1N22 A;  3RBM A;  4KQS A;  4PVX F;  4KK2 A;  1RTR A;  2J5C A;  3OAB B;  4JYX A;  3WJO A;  4RYP A;  1KIY A;  4DZW A;  4RNQ A;  5ERO A;  4F6X A;  3N3L F;  3ACW A;  3WCM A;  3LDW A;  3N46 F;  2DH4 A;  4E9U A;  3Q1O A;  3LVS A;  1HXA A;  1V4K A;  4RXD A;  5ILD A;  4NKF A;  1YHK A;  2Z4W A;  3LG5 A;  1WL1 A;  1PS1 A;  3LMD A;  1V4E A;  2AEK A;  2J1P A;  4NG6 A;  1HM7 A;  5IL3 A;  2EWG A;  4OMG A;  3P41 A;  1HXG A;  3SDT A;  4JXN A;  2Z50 A;  2Q9Y A;  3KRA B;  5DGM F;  4KQU A;  3SDV A;  2F8Z F;  3RYE A;  2PS8 A;  2F92 F;  4NFK F;  2OPM A;  3IBA A;  5DJR F;  2ZY1 A;  4XQT F;  4JZB A;  1YV5 A;  5HN9 A;  5JUZ F;  2OGD A;  3TFP A;  4NUA A;  2ZCS A;  4JVJ F;  3N5H F;  3N1V F;  4LLS A;  5EAS A;  5IMN A;  3PKO A;  3QQV A;  1YYT A;  4H5D F;  5HN8 A;  3AQB B;  2Z78 A;  4OKZ A;  4KVY A;  3TFN A;  3WCB A;  3WEG A;  1YHL A;  1YYU A;  4LZ0 A;  4RXA A;  3M00 A;  3LGK A;  4DHD A;  2Z52 A;  1EZF A;  5DHK A;  5C05 A;  4KUX A;  3PH7 A;  5IK6 A;  1JFG A;  5JV1 F;  1ZW5 A;  4NFJ F;  4RXE A;  3ACX A;  3EFQ A;  3M9U A;  1N21 A;  4H5C F;  5ERN A;  4LXW A;  4NFI F;  5ERM A;  3ZOU A;  3V66 A;  3SDR A;  3LSN A;  2E4O A;  3SDQ A;  4KFA A;  3WSB A;  5CG5 A;  5ILJ A;  5ILZ A;  1UBX A;  1V4H A;  3UCA A;  2Z4V A;  2AEL A;  3P5P A;  4DWG A;  5B01 A;  4KVW A;  4RXC A;  5AYP A;  3DYF A;  3KB9 A;  3VJC A;  4LFG A;  4KVI A;  5JV0 F;  3VJD A;  2PS7 A;  5DGS F;  5B03 A;  5B0K A;  2PS6 A;  2Q9Z A;  2Q58 A;  3N3D A;  3OYR A;  4XQS F;  4LOB A;  4LFV F;  5ILI A;  3ID0 A;  2ZEU A;  3ASX A;  4H5E F;  5JV2 F;  3WSA A;  4LFE A;  2E8U A;  3SAE A;  3VJB A;  2I19 A;  1UBW A;  5B0I A;  2F8C F;  3N0F A;  1HM4 A;  3WEK A;  1UBY A;  2Q80 A;  5B0L A;  2Z4Y A;  4K10 A;  3LK5 A;  1YYS A;  3G4F A;  3ZMC A;  2FOR A;  4L2X F;  3NF2 A;  1N24 A;  3LJI A;  3ICZ A;  1FPS A;  3N45 F;  1YYQ A;  5I1U A;  3Q30 A;  3BNX A;  2P1C A;  3OAC A;  3AQC B;  3PDE A;  1WMW A;  3DYG A; 
#chains in the Genus database with same CATH homology
 3KRP A;  3KRO B;  4DWB A;  5HNA A;  2ZCO A;  3N49 F;  1V4J A;  3EZ3 A;  4FJQ A;  4LZ3 A;  4MC3 A;  3ZCD A;  5IMI A;  3ZMB A;  1UBV A;  4UMJ A;  4N9U A;  2ONH A;  4GA3 A;  3WCG A;  3Q2Z A;  4P0V A;  5E8L A;  1KIZ A;  1N1B A;  4Q23 A;  2PS4 A;  2E8W A;  3CKE A;  4OKM A;  4FP4 A;  3ACY A;  5HN7 A;  5AHU B;  3V1V A;  1RQI A;  2E8X A;  5A0J A;  5E8H A;  3AQ0 A;  3ADZ A;  3OAB A;  4E9Z A;  1YYR A;  5DJV F;  3WCH A;  2F94 F;  4KPD A;  3Q2Q A;  4LA5 A;  5B02 A;  3TS7 A;  3B7L A;  4KPJ A;  4MC0 A;  4F62 A;  5IVG A;  5AEL A;  1DGP A;  5IKH A;  4LZC A;  3P8L A;  3QKC A;  5DJP F;  2F7M F;  1N23 A;  3NPK A;  3NPR A;  3PYB A;  4LTZ A;  3ICK A;  1VG4 A;  4F6V A;  2QIS A;  5DZ2 A;  3KRA A;  2E92 A;  5DHI A;  4JXY A;  5B0M A;  3WEI A;  5DGN F;  4OGU A;  3KRC A;  1HX9 A;  3KRF A;  2FTZ A;  4KKM A;  4XQR F;  4OMH A;  3NRI A;  5A0K A;  3LZ9 A;  2AZK A;  2E90 A;  2ZEV A;  3WCI A;  3EGT A;  4KWD A;  2ZCQ A;  2ONG A;  1YJ4 A;  3M01 A;  5IN8 A;  1V4I A;  3VJ8 A;  1N20 A;  1N1Z A;  1VG6 A;  3WE9 A;  3WCL A;  5ILH A;  3WC9 A;  3PYA A;  2PS5 A;  4NKE A;  5IM1 A;  4QXS F;  3LOM A;  5EAT A;  3WJK A;  3N1W F;  3RYW A;  2E8V A;  5KSX F;  2F89 F;  3WEH A;  3S4J A;  1WY0 A;  4LLT A;  2J1O A;  3KBK A;  3WCJ A;  2AZL A;  3TC1 A;  5ILY A;  4KQ5 A;  2AZJ A;  5DW7 A;  5E8K A;  4PVY F;  5AFX A;  2E95 A;  3AE0 A;  2Z4X A;  1WL0 A;  3VJA A;  4LUU A;  1WKZ A;  3S9V A;  3WCE A;  3LLW A;  1JFA A;  4EA1 A;  3MAV A;  2E91 A;  5CG6 A;  1YHM A;  1RQJ A;  4P0X A;  3KRC B;  3KRF B;  4EA0 A;  5EAU A;  1VG7 A;  2Z7I A;  1DI1 A;  5IK9 A;  4DEM F;  3P8R A;  2Z4Z A;  3WEF A;  3RMG A;  3LGZ B;  5A0I A;  4LTV A;  5B0J A;  3ZL6 A;  5JA0 F;  1HXC A;  3N6K F;  3VJE A;  2H8O A;  4N1Z F;  1VG3 A;  3P5R A;  3IPI A;  5IK0 A;  3ICN A;  3WCA A;  4LPG F;  2E8T A;  3LEE A;  5IL8 A;  3TFV A;  4LIX A;  2F9K F;  3APZ A;  4HD1 A;  1WL3 A;  4DI5 A;  4E1E A;  4QPF A;  2AET A;  3DYH A;  4MC8 A;  4GAX A;  1YQ7 A;  3WJN A;  4LA6 A;  4DXJ A;  3OAC B;  3ICM A;  3M0G A;  3SDU A;  3MZV A;  4ZQ8 A;  1VG2 A;  5IMP A;  3G4D A;  2O1O A;  3KRP B;  5H9D A;  5DIQ F;  3M02 A;  4JZX A;  3V1X A;  3WEJ A;  2OA6 A;  2OPN A;  3WCF A;  3CP6 A;  4KVD A;  3N0G A;  5ER8 A;  3WCD A;  3KRO A;  2VF6 A;  4GP2 A;  4LPH F;  5IKA A;  2ZCR A;  5B00 A;  2Z7H A;  2RAH A;  4WK5 A;  4P0W A;  3CC9 A;  4EA2 A;  2E94 A;  3BNY A;  2E93 A;  3W7F A;  3WCC A;  5ILK A;  1WL2 A;  3N5J F;  4GP1 A;  3VJ9 A;  1N22 A;  3RBM A;  4KQS A;  4PVX F;  4KK2 A;  1RTR A;  2J5C A;  3OAB B;  4JYX A;  3WJO A;  4RYP A;  1KIY A;  4DZW A;  4RNQ A;  5ERO A;  4F6X A;  3N3L F;  3ACW A;  3WCM A;  3LDW A;  3N46 F;  2DH4 A;  4E9U A;  3Q1O A;  3LVS A;  1HXA A;  1V4K A;  4RXD A;  5ILD A;  4NKF A;  1YHK A;  2Z4W A;  3LG5 A;  1WL1 A;  1PS1 A;  3LMD A;  1V4E A;  2AEK A;  2J1P A;  4NG6 A;  1HM7 A;  5IL3 A;  2EWG A;  4OMG A;  3P41 A;  1HXG A;  3SDT A;  4JXN A;  2Z50 A;  2Q9Y A;  3KRA B;  5DGM F;  4KQU A;  3SDV A;  2F8Z F;  3RYE A;  2PS8 A;  2F92 F;  4NFK F;  2OPM A;  3IBA A;  5DJR F;  2ZY1 A;  4XQT F;  4JZB A;  1YV5 A;  5HN9 A;  5JUZ F;  2OGD A;  3TFP A;  4NUA A;  2ZCS A;  4JVJ F;  3N5H F;  3N1V F;  4LLS A;  5EAS A;  5IMN A;  3PKO A;  3QQV A;  1YYT A;  4H5D F;  5HN8 A;  3AQB B;  2Z78 A;  4OKZ A;  4KVY A;  3TFN A;  3WCB A;  3WEG A;  1YHL A;  1YYU A;  4LZ0 A;  4RXA A;  3M00 A;  3LGK A;  4DHD A;  2Z52 A;  1EZF A;  5DHK A;  5C05 A;  4KUX A;  3PH7 A;  5IK6 A;  1JFG A;  5JV1 F;  1ZW5 A;  4NFJ F;  4RXE A;  3ACX A;  3EFQ A;  3M9U A;  1N21 A;  4H5C F;  5ERN A;  4LXW A;  4NFI F;  5ERM A;  3ZOU A;  3V66 A;  3SDR A;  3LSN A;  2E4O A;  3SDQ A;  4KFA A;  3WSB A;  5CG5 A;  5ILJ A;  5ILZ A;  1UBX A;  1V4H A;  3UCA A;  2Z4V A;  2AEL A;  3P5P A;  4DWG A;  5B01 A;  4KVW A;  4RXC A;  5AYP A;  3DYF A;  3KB9 A;  3VJC A;  4LFG A;  4KVI A;  5JV0 F;  3VJD A;  2PS7 A;  5DGS F;  5B03 A;  5B0K A;  2PS6 A;  2Q9Z A;  2Q58 A;  3N3D A;  3OYR A;  4XQS F;  4LOB A;  4LFV F;  5ILI A;  3ID0 A;  2ZEU A;  3ASX A;  4H5E F;  5JV2 F;  3WSA A;  4LFE A;  2E8U A;  3SAE A;  3VJB A;  2I19 A;  1UBW A;  5B0I A;  2F8C F;  3N0F A;  1HM4 A;  3WEK A;  1UBY A;  2Q80 A;  5B0L A;  2Z4Y A;  4K10 A;  3LK5 A;  1YYS A;  3G4F A;  3ZMC A;  2FOR A;  4L2X F;  3NF2 A;  1N24 A;  3LJI A;  3ICZ A;  1FPS A;  3N45 F;  1YYQ A;  5I1U A;  3Q30 A;  3BNX A;  2P1C A;  3OAC A;  3AQC B;  3PDE A;  1WMW A;  3DYG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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