3WCFA

The complex structure of hssqs wtih ligand,bph1218
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
334
structure length
334
Chain Sequence
LSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFALPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVLIRLGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSNPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Squalene synthase as a target for Chagas disease therapeutics.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 132
structure length 334
sequence length 334
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2013-05-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3wcfA00
3WCGA 3VJ8A 3N0FA 3ACWA 4LZCA 2ONHA 3TC1A 5B01A 5B0JA 3RYEA 4LXWA 5JV1F 5B0LA 5IK9A 3WSAA 2AEKA 2E92A 3P41A 5B0IA 5ILDA 1V4IA 3WJKA 1YHMA 3IBAA 2Z4XA 3V66A 3N3DA 4GAXA 3KBKA 1ZW5A 5A0IA 4GP1A 4P0WA 5ERMA 3WCFA 5DGMF 4NUAA 2AELA 1YQ7A 1RTRA 2F8ZF 3WSBA 4RNQA 4PVXF 3WCJA 3N45F 2Z78A 3LJIA 2PS8A 3WCEA 3WEHA 4LA6A 2I19A 4MC3A 1UBWA 4LOBA 4F62A 4MC8A 3ACXA 2F92F 5HN8A 1YYTA 4RYPA 3KB9A 3M9UA 2Z4VA 3SDUA 3LLWA 3ICKA 4QPFA 4XQTF 5HNAA 5DGNF 3B7LA 3APZA 3ICMA 3KRAA 2F9KF 2ZEUA 3G4DA 3WCMA 2E90A 4KWDA 3WCLA 3BNXA 1N20A 5IMPA 3LGKA 4LFVF 1DI1A 5EATA 3QKCA 3ZOUA 4RXDA 3WCBA 3LDWA 2Q9YA 3N1VF 5H9DA 5JA0F 1EZFA 3EFQA 5IKHA 1N23A 3N6KF 2Q58A 4KKMA 5IKAA 5B0KA 3V1XA 1V4KA 1WMWA 1N24A 3AQBB 2Z50A 2F89F 3N5HF 1WL0A 3VJEA 4KVWA 4XQSF 3P8RA 4KFAA 3Q2QA 4LA5A 5B03A 3PKOA 3OYRA 3Q2ZA 1JFGA 1HXGA 5CG5A 3AQCB 4OMHA 2ZY1A 1N1BA 4JZXA 5CG6A 4F6VA 3MZVA 4UMJA 3ID0A 4JZBA 4XQRF 2Z7HA 3SDTA 3LZ9A 5AHUB 2AETA 3VJDA 4PVYF 2ZCOA 5HN7A 4DWBA 4DHDA 4LLTA 4QXSF 4DWGA 3KRPB 3AE0A 3OACB 5HN9A 3WEKA 5ERNA 4EA0A 5EROA 3VJCA 2DH4A 3P5RA 5IL8A 2J5CA 3SAEA 3LEEA 3PYAA 1WL3A 4OKZA 2AZLA 1YYUA 5C05A 2PS6A 1WL1A 5JUZF 2O1OA 4H5CF 3RYWA 5EAUA 3VJAA 2E95A 3M00A 4ZQ8A 4KPJA 1YJ4A 5DJRF 3KRFA 3LK5A 3WCDA 4OMGA 3NF2A 5DZ2A 5AYPA 1PS1A 2RAHA 2OPMA 1WKZA 3TS7A 5IMIA 4RXAA 1VG2A 5ILIA 4OKMA 3DYFA 5DGSF 2ZCRA 3ZMBA 3WJOA 4DEMF 5IMNA 2E94A 3S4JA 3WEJA 3NPKA 5ILYA 2Q9ZA 3PYBA 5E8LA 2Z7IA 3RBMA 4NKFA 1YYQA 3CKEA 3KRFB 1YHKA 1YYSA 5IVGA 5DW7A 4LZ0A 2E8XA 4OGUA 1VG3A 4LUUA 3EGTA 4LIXA 3V1VA 3WEIA 2E8TA 4WK5A 5IL3A 4JXYA 3N5JF 3N49F 2FTZA 2J1OA 3SDRA 1JFAA 2ZCQA 5ILJA 4MC0A 3NRIA 5AFXA 4LPGF 4LZ3A 2AZJA 4DZWA 1N21A 3KRCA 1YHLA 3PDEA 5DHKA 3P8LA 4EA1A 3KRPA 3OACA 5A0KA 5ILKA 2E91A 1WL2A 1RQJA 4E9ZA 3VJBA 3WJNA 3ZCDA 4GP2A 3G4FA 5DHIA 4NFJF 3P5PA 3WC9A 4LPHF 3WCAA 1HXAA 1WY0A 1UBXA 4E1EA 5B02A 1RQIA 3MAVA 3NPRA 1UBYA 1UBVA 3DYGA 4KQSA 2ONGA 3SDQA 3KRCB 5IK0A 4K10A 5DJPF 2ZCSA 1HM7A 4RXCA 4NKEA 4GA3A 4LLSA 4DXJA 3LOMA 5EASA 5JV2F 1KIYA 2F8CF 4LFEA 4P0XA 4LTZA 3WEGA 4KVYA 5KSXF 4RXEA 2OGDA 2AZKA 5I1UA 2PS7A 3CP6A 3WCIA 4LFGA 3OABA 5A0JA 4NFKF 1DGPA 5E8KA 3TFNA 4E9UA 4LTVA 3VJ9A 5B0MA 5AELA 3M02A 3EZ3A 3LMDA 3WEFA 3RMGA 4KPDA 3ICZA 5ILZA 1N1ZA 4N9UA 4EA2A 5E8HA 1V4HA 4Q23A 2Q80A 4JVJF 3KROA 2ZEVA 1V4JA 1YV5A 2Z4YA 3N46F 4DI5A 5B00A 1HM4A 3LG5A 4NG6A 5ER8A 4F6XA 3TFVA 2PS5A 1N22A 3Q30A 4N1ZF 3ZL6A 4KK2A 3LGZB 2Z4ZA 4HD1A 3S9VA 2E93A 3OABB 2F7MF 3M0GA 3UCAA 3ASXA 2E4OA 2E8WA 2Z52A 3CC9A 5JV0F 3W7FA 2OA6A 3SDVA 3AQ0A 3N0GA 3QQVA 3Q1OA 3PH7A 3WCCA 1VG4A 3LSNA 1HXCA 3KROB 5DIQF 2PS4A 2H8OA 3ADZA 4KQ5A 4L2XF 3ZMCA 3N1WF 3IPIA 4NFIF 3ACYA 1KIZA 3ICNA 3LVSA 4JYXA 2E8UA 4KVDA 2P1CA 5IM1A 2FORA 2QISA 3BNYA 3TFPA 5IN8A 3DYHA 4H5EF 1VG6A 1VG7A 4KQUA 3KRAB 3WE9A 4KUXA 4KVIA 3M01A 5DJVF 5ILHA 2OPNA 4P0VA 2EWGA 5IK6A 3N3LF 1HX9A 3WCHA 1FPSA 1YYRA 4JXNA 2J1PA 2Z4WA 1V4EA 4FJQA 2E8VA 4FP4A 4H5DF 2VF6A 2F94F
chains in the Genus database with same CATH superfamily
3WCGA 3VJ8A 3N0FA 3ACWA 4LZCA 2ONHA 3TC1A 5B01A 5B0JA 3RYEA 4LXWA 5JV1F 5B0LA 5IK9A 3WSAA 2AEKA 2E92A 3P41A 5B0IA 5ILDA 1V4IA 3WJKA 1YHMA 3IBAA 2Z4XA 3V66A 3N3DA 4GAXA 3KBKA 1ZW5A 5A0IA 4GP1A 4P0WA 5ERMA 3WCFA 5DGMF 4NUAA 2AELA 1YQ7A 1RTRA 2F8ZF 3WSBA 4RNQA 4PVXF 3WCJA 3N45F 2Z78A 3LJIA 2PS8A 3WCEA 3WEHA 4LA6A 2I19A 4MC3A 1UBWA 4LOBA 4F62A 4MC8A 3ACXA 2F92F 5HN8A 1YYTA 4RYPA 3KB9A 3M9UA 2Z4VA 3SDUA 3LLWA 3ICKA 4QPFA 4XQTF 5HNAA 5DGNF 3B7LA 3APZA 3ICMA 3KRAA 2F9KF 2ZEUA 3G4DA 3WCMA 2E90A 4KWDA 3WCLA 3BNXA 1N20A 5IMPA 3LGKA 4LFVF 1DI1A 5EATA 3QKCA 3ZOUA 4RXDA 3WCBA 3LDWA 2Q9YA 3N1VF 5H9DA 5JA0F 1EZFA 3EFQA 5IKHA 1N23A 3N6KF 2Q58A 4KKMA 5IKAA 5B0KA 3V1XA 1V4KA 1WMWA 1N24A 3AQBB 2Z50A 2F89F 3N5HF 1WL0A 3VJEA 4KVWA 4XQSF 3P8RA 4KFAA 3Q2QA 4LA5A 5B03A 3PKOA 3OYRA 3Q2ZA 1JFGA 1HXGA 5CG5A 3AQCB 4OMHA 2ZY1A 1N1BA 4JZXA 5CG6A 4F6VA 3MZVA 4UMJA 3ID0A 4JZBA 4XQRF 2Z7HA 3SDTA 3LZ9A 5AHUB 2AETA 3VJDA 4PVYF 2ZCOA 5HN7A 4DWBA 4DHDA 4LLTA 4QXSF 4DWGA 3KRPB 3AE0A 3OACB 5HN9A 3WEKA 5ERNA 4EA0A 5EROA 3VJCA 2DH4A 3P5RA 5IL8A 2J5CA 3SAEA 3LEEA 3PYAA 1WL3A 4OKZA 2AZLA 1YYUA 5C05A 2PS6A 1WL1A 5JUZF 2O1OA 4H5CF 3RYWA 5EAUA 3VJAA 2E95A 3M00A 4ZQ8A 4KPJA 1YJ4A 5DJRF 3KRFA 3LK5A 3WCDA 4OMGA 3NF2A 5DZ2A 5AYPA 1PS1A 2RAHA 2OPMA 1WKZA 3TS7A 5IMIA 4RXAA 1VG2A 5ILIA 4OKMA 3DYFA 5DGSF 2ZCRA 3ZMBA 3WJOA 4DEMF 5IMNA 2E94A 3S4JA 3WEJA 3NPKA 5ILYA 2Q9ZA 3PYBA 5E8LA 2Z7IA 3RBMA 4NKFA 1YYQA 3CKEA 3KRFB 1YHKA 1YYSA 5IVGA 5DW7A 4LZ0A 2E8XA 4OGUA 1VG3A 4LUUA 3EGTA 4LIXA 3V1VA 3WEIA 2E8TA 4WK5A 5IL3A 4JXYA 3N5JF 3N49F 2FTZA 2J1OA 3SDRA 1JFAA 2ZCQA 5ILJA 4MC0A 3NRIA 5AFXA 4LPGF 4LZ3A 2AZJA 4DZWA 1N21A 3KRCA 1YHLA 3PDEA 5DHKA 3P8LA 4EA1A 3KRPA 3OACA 5A0KA 5ILKA 2E91A 1WL2A 1RQJA 4E9ZA 3VJBA 3WJNA 3ZCDA 4GP2A 3G4FA 5DHIA 4NFJF 3P5PA 3WC9A 4LPHF 3WCAA 1HXAA 1WY0A 1UBXA 4E1EA 5B02A 1RQIA 3MAVA 3NPRA 1UBYA 1UBVA 3DYGA 4KQSA 2ONGA 3SDQA 3KRCB 5IK0A 4K10A 5DJPF 2ZCSA 1HM7A 4RXCA 4NKEA 4GA3A 4LLSA 4DXJA 3LOMA 5EASA 5JV2F 1KIYA 2F8CF 4LFEA 4P0XA 4LTZA 3WEGA 4KVYA 5KSXF 4RXEA 2OGDA 2AZKA 5I1UA 2PS7A 3CP6A 3WCIA 4LFGA 3OABA 5A0JA 4NFKF 1DGPA 5E8KA 3TFNA 4E9UA 4LTVA 3VJ9A 5B0MA 5AELA 3M02A 3EZ3A 3LMDA 3WEFA 3RMGA 4KPDA 3ICZA 5ILZA 1N1ZA 4N9UA 4EA2A 5E8HA 1V4HA 4Q23A 2Q80A 4JVJF 3KROA 2ZEVA 1V4JA 1YV5A 2Z4YA 3N46F 4DI5A 5B00A 1HM4A 3LG5A 4NG6A 5ER8A 4F6XA 3TFVA 2PS5A 1N22A 3Q30A 4N1ZF 3ZL6A 4KK2A 3LGZB 2Z4ZA 4HD1A 3S9VA 2E93A 3OABB 2F7MF 3M0GA 3UCAA 3ASXA 2E4OA 2E8WA 2Z52A 3CC9A 5JV0F 3W7FA 2OA6A 3SDVA 3AQ0A 3N0GA 3QQVA 3Q1OA 3PH7A 3WCCA 1VG4A 3LSNA 1HXCA 3KROB 5DIQF 2PS4A 2H8OA 3ADZA 4KQ5A 4L2XF 3ZMCA 3N1WF 3IPIA 4NFIF 3ACYA 1KIZA 3ICNA 3LVSA 4JYXA 2E8UA 4KVDA 2P1CA 5IM1A 2FORA 2QISA 3BNYA 3TFPA 5IN8A 3DYHA 4H5EF 1VG6A 1VG7A 4KQUA 3KRAB 3WE9A 4KUXA 4KVIA 3M01A 5DJVF 5ILHA 2OPNA 4P0VA 2EWGA 5IK6A 3N3LF 1HX9A 3WCHA 1FPSA 1YYRA 4JXNA 2J1PA 2Z4WA 1V4EA 4FJQA 2E8VA 4FP4A 4H5DF 2VF6A 2F94F
chains in the Genus database with same CATH topology
3WCGA 3VJ8A 3N0FA 3ACWA 4LZCA 2ONHA 3TC1A 5B01A 5B0JA 3RYEA 4LXWA 5JV1F 5B0LA 5IK9A 3WSAA 2AEKA 2E92A 3P41A 5B0IA 5ILDA 1V4IA 3WJKA 1YHMA 3IBAA 2Z4XA 3V66A 3N3DA 4GAXA 3KBKA 1ZW5A 5A0IA 4GP1A 4P0WA 5ERMA 3WCFA 5DGMF 4NUAA 2AELA 1YQ7A 1RTRA 2F8ZF 3WSBA 4RNQA 4PVXF 3WCJA 3N45F 2Z78A 3LJIA 2PS8A 3WCEA 3WEHA 4LA6A 2I19A 4MC3A 1UBWA 4LOBA 4F62A 4MC8A 3ACXA 2F92F 5HN8A 1YYTA 4RYPA 3KB9A 3M9UA 2Z4VA 3SDUA 3LLWA 3ICKA 4QPFA 4XQTF 5HNAA 5DGNF 3B7LA 3APZA 3ICMA 3KRAA 2F9KF 2ZEUA 3G4DA 3WCMA 2E90A 4KWDA 3WCLA 3BNXA 1N20A 5IMPA 3LGKA 4LFVF 1DI1A 5EATA 3QKCA 3ZOUA 4RXDA 3WCBA 3LDWA 2Q9YA 3N1VF 5H9DA 5JA0F 1EZFA 3EFQA 5IKHA 1N23A 3N6KF 2Q58A 4KKMA 5IKAA 5B0KA 3V1XA 1V4KA 1WMWA 1N24A 3AQBB 2Z50A 2F89F 3N5HF 1WL0A 3VJEA 4KVWA 4XQSF 3P8RA 4KFAA 3Q2QA 4LA5A 5B03A 3PKOA 3OYRA 3Q2ZA 1JFGA 1HXGA 5CG5A 3AQCB 4OMHA 2ZY1A 1N1BA 4JZXA 5CG6A 4F6VA 3MZVA 4UMJA 3ID0A 4JZBA 4XQRF 2Z7HA 3SDTA 3LZ9A 5AHUB 2AETA 3VJDA 4PVYF 2ZCOA 5HN7A 4DWBA 4DHDA 4LLTA 4QXSF 4DWGA 3KRPB 3AE0A 3OACB 5HN9A 3WEKA 5ERNA 4EA0A 5EROA 3VJCA 2DH4A 3P5RA 5IL8A 2J5CA 3SAEA 3LEEA 3PYAA 1WL3A 4OKZA 2AZLA 1YYUA 5C05A 2PS6A 1WL1A 5JUZF 2O1OA 4H5CF 3RYWA 5EAUA 3VJAA 2E95A 3M00A 4ZQ8A 4KPJA 1YJ4A 5DJRF 3KRFA 3LK5A 3WCDA 4OMGA 3NF2A 5DZ2A 5AYPA 1PS1A 2RAHA 2OPMA 1WKZA 3TS7A 5IMIA 4RXAA 1VG2A 5ILIA 4OKMA 3DYFA 5DGSF 2ZCRA 3ZMBA 3WJOA 4DEMF 5IMNA 2E94A 3S4JA 3WEJA 3NPKA 5ILYA 2Q9ZA 3PYBA 5E8LA 2Z7IA 3RBMA 4NKFA 1YYQA 3CKEA 3KRFB 1YHKA 1YYSA 5IVGA 5DW7A 4LZ0A 2E8XA 4OGUA 1VG3A 4LUUA 3EGTA 4LIXA 3V1VA 3WEIA 2E8TA 4WK5A 5IL3A 4JXYA 3N5JF 3N49F 2FTZA 2J1OA 3SDRA 1JFAA 2ZCQA 5ILJA 4MC0A 3NRIA 5AFXA 4LPGF 4LZ3A 2AZJA 4DZWA 1N21A 3KRCA 1YHLA 3PDEA 5DHKA 3P8LA 4EA1A 3KRPA 3OACA 5A0KA 5ILKA 2E91A 1WL2A 1RQJA 4E9ZA 3VJBA 3WJNA 3ZCDA 4GP2A 3G4FA 5DHIA 4NFJF 3P5PA 3WC9A 4LPHF 3WCAA 1HXAA 1WY0A 1UBXA 4E1EA 5B02A 1RQIA 3MAVA 3NPRA 1UBYA 1UBVA 3DYGA 4KQSA 2ONGA 3SDQA 3KRCB 5IK0A 4K10A 5DJPF 2ZCSA 1HM7A 4RXCA 4NKEA 4GA3A 4LLSA 4DXJA 3LOMA 5EASA 5JV2F 1KIYA 2F8CF 4LFEA 4P0XA 4LTZA 3WEGA 4KVYA 5KSXF 4RXEA 2OGDA 2AZKA 5I1UA 2PS7A 3CP6A 3WCIA 4LFGA 3OABA 5A0JA 4NFKF 1DGPA 5E8KA 3TFNA 4E9UA 4LTVA 3VJ9A 5B0MA 5AELA 3M02A 3EZ3A 3LMDA 3WEFA 3RMGA 4KPDA 3ICZA 5ILZA 1N1ZA 4N9UA 4EA2A 5E8HA 1V4HA 4Q23A 2Q80A 4JVJF 3KROA 2ZEVA 1V4JA 1YV5A 2Z4YA 3N46F 4DI5A 5B00A 1HM4A 3LG5A 4NG6A 5ER8A 4F6XA 3TFVA 2PS5A 1N22A 3Q30A 4N1ZF 3ZL6A 4KK2A 3LGZB 2Z4ZA 4HD1A 3S9VA 2E93A 3OABB 2F7MF 3M0GA 3UCAA 3ASXA 2E4OA 2E8WA 2Z52A 3CC9A 5JV0F 3W7FA 2OA6A 3SDVA 3AQ0A 3N0GA 3QQVA 3Q1OA 3PH7A 3WCCA 1VG4A 3LSNA 1HXCA 3KROB 5DIQF 2PS4A 2H8OA 3ADZA 4KQ5A 4L2XF 3ZMCA 3N1WF 3IPIA 4NFIF 3ACYA 1KIZA 3ICNA 3LVSA 4JYXA 2E8UA 4KVDA 2P1CA 5IM1A 2FORA 2QISA 3BNYA 3TFPA 5IN8A 3DYHA 4H5EF 1VG6A 1VG7A 4KQUA 3KRAB 3WE9A 4KUXA 4KVIA 3M01A 5DJVF 5ILHA 2OPNA 4P0VA 2EWGA 5IK6A 3N3LF 1HX9A 3WCHA 1FPSA 1YYRA 4JXNA 2J1PA 2Z4WA 1V4EA 4FJQA 2E8VA 4FP4A 4H5DF 2VF6A 2F94F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WCG A;  3VJ8 A;  3N0F A;  3ACW A;  4LZC A;  2ONH A;  3TC1 A;  5B01 A;  5B0J A;  3RYE A;  4LXW A;  5JV1 F;  5B0L A;  5IK9 A;  3WSA A;  2AEK A;  2E92 A;  3P41 A;  5B0I A;  5ILD A;  1V4I A;  3WJK A;  1YHM A;  3IBA A;  2Z4X A;  3V66 A;  3N3D A;  4GAX A;  3KBK A;  1ZW5 A;  5A0I A;  4GP1 A;  4P0W A;  5ERM A;  3WCF A;  5DGM F;  4NUA A;  2AEL A;  1YQ7 A;  1RTR A;  2F8Z F;  3WSB A;  4RNQ A;  4PVX F;  3WCJ A;  3N45 F;  2Z78 A;  3LJI A;  2PS8 A;  3WCE A;  3WEH A;  4LA6 A;  2I19 A;  4MC3 A;  1UBW A;  4LOB A;  4F62 A;  4MC8 A;  3ACX A;  2F92 F;  5HN8 A;  1YYT A;  4RYP A;  3KB9 A;  3M9U A;  2Z4V A;  3SDU A;  3LLW A;  3ICK A;  4QPF A;  4XQT F;  5HNA A;  5DGN F;  3B7L A;  3APZ A;  3ICM A;  3KRA A;  2F9K F;  2ZEU A;  3G4D A;  3WCM A;  2E90 A;  4KWD A;  3WCL A;  3BNX A;  1N20 A;  5IMP A;  3LGK A;  4LFV F;  1DI1 A;  5EAT A;  3QKC A;  3ZOU A;  4RXD A;  3WCB A;  3LDW A;  2Q9Y A;  3N1V F;  5H9D A;  5JA0 F;  1EZF A;  3EFQ A;  5IKH A;  1N23 A;  3N6K F;  2Q58 A;  4KKM A;  5IKA A;  5B0K A;  3V1X A;  1V4K A;  1WMW A;  1N24 A;  3AQB B;  2Z50 A;  2F89 F;  3N5H F;  1WL0 A;  3VJE A;  4KVW A;  4XQS F;  3P8R A;  4KFA A;  3Q2Q A;  4LA5 A;  5B03 A;  3PKO A;  3OYR A;  3Q2Z A;  1JFG A;  1HXG A;  5CG5 A;  3AQC B;  4OMH A;  2ZY1 A;  1N1B A;  4JZX A;  5CG6 A;  4F6V A;  3MZV A;  4UMJ A;  3ID0 A;  4JZB A;  4XQR F;  2Z7H A;  3SDT A;  3LZ9 A;  5AHU B;  2AET A;  3VJD A;  4PVY F;  2ZCO A;  5HN7 A;  4DWB A;  4DHD A;  4LLT A;  4QXS F;  4DWG A;  3KRP B;  3AE0 A;  3OAC B;  5HN9 A;  3WEK A;  5ERN A;  4EA0 A;  5ERO A;  3VJC A;  2DH4 A;  3P5R A;  5IL8 A;  2J5C A;  3SAE A;  3LEE A;  3PYA A;  1WL3 A;  4OKZ A;  2AZL A;  1YYU A;  5C05 A;  2PS6 A;  1WL1 A;  5JUZ F;  2O1O A;  4H5C F;  3RYW A;  5EAU A;  3VJA A;  2E95 A;  3M00 A;  4ZQ8 A;  4KPJ A;  1YJ4 A;  5DJR F;  3KRF A;  3LK5 A;  3WCD A;  4OMG A;  3NF2 A;  5DZ2 A;  5AYP A;  1PS1 A;  2RAH A;  2OPM A;  1WKZ A;  3TS7 A;  5IMI A;  4RXA A;  1VG2 A;  5ILI A;  4OKM A;  3DYF A;  5DGS F;  2ZCR A;  3ZMB A;  3WJO A;  4DEM F;  5IMN A;  2E94 A;  3S4J A;  3WEJ A;  3NPK A;  5ILY A;  2Q9Z A;  3PYB A;  5E8L A;  2Z7I A;  3RBM A;  4NKF A;  1YYQ A;  3CKE A;  3KRF B;  1YHK A;  1YYS A;  5IVG A;  5DW7 A;  4LZ0 A;  2E8X A;  4OGU A;  1VG3 A;  4LUU A;  3EGT A;  4LIX A;  3V1V A;  3WEI A;  2E8T A;  4WK5 A;  5IL3 A;  4JXY A;  3N5J F;  3N49 F;  2FTZ A;  2J1O A;  3SDR A;  1JFA A;  2ZCQ A;  5ILJ A;  4MC0 A;  3NRI A;  5AFX A;  4LPG F;  4LZ3 A;  2AZJ A;  4DZW A;  1N21 A;  3KRC A;  1YHL A;  3PDE A;  5DHK A;  3P8L A;  4EA1 A;  3KRP A;  3OAC A;  5A0K A;  5ILK A;  2E91 A;  1WL2 A;  1RQJ A;  4E9Z A;  3VJB A;  3WJN A;  3ZCD A;  4GP2 A;  3G4F A;  5DHI A;  4NFJ F;  3P5P A;  3WC9 A;  4LPH F;  3WCA A;  1HXA A;  1WY0 A;  1UBX A;  4E1E A;  5B02 A;  1RQI A;  3MAV A;  3NPR A;  1UBY A;  1UBV A;  3DYG A;  4KQS A;  2ONG A;  3SDQ A;  3KRC B;  5IK0 A;  4K10 A;  5DJP F;  2ZCS A;  1HM7 A;  4RXC A;  4NKE A;  4GA3 A;  4LLS A;  4DXJ A;  3LOM A;  5EAS A;  5JV2 F;  1KIY A;  2F8C F;  4LFE A;  4P0X A;  4LTZ A;  3WEG A;  4KVY A;  5KSX F;  4RXE A;  2OGD A;  2AZK A;  5I1U A;  2PS7 A;  3CP6 A;  3WCI A;  4LFG A;  3OAB A;  5A0J A;  4NFK F;  1DGP A;  5E8K A;  3TFN A;  4E9U A;  4LTV A;  3VJ9 A;  5B0M A;  5AEL A;  3M02 A;  3EZ3 A;  3LMD A;  3WEF A;  3RMG A;  4KPD A;  3ICZ A;  5ILZ A;  1N1Z A;  4N9U A;  4EA2 A;  5E8H A;  1V4H A;  4Q23 A;  2Q80 A;  4JVJ F;  3KRO A;  2ZEV A;  1V4J A;  1YV5 A;  2Z4Y A;  3N46 F;  4DI5 A;  5B00 A;  1HM4 A;  3LG5 A;  4NG6 A;  5ER8 A;  4F6X A;  3TFV A;  2PS5 A;  1N22 A;  3Q30 A;  4N1Z F;  3ZL6 A;  4KK2 A;  3LGZ B;  2Z4Z A;  4HD1 A;  3S9V A;  2E93 A;  3OAB B;  2F7M F;  3M0G A;  3UCA A;  3ASX A;  2E4O A;  2E8W A;  2Z52 A;  3CC9 A;  5JV0 F;  3W7F A;  2OA6 A;  3SDV A;  3AQ0 A;  3N0G A;  3QQV A;  3Q1O A;  3PH7 A;  3WCC A;  1VG4 A;  3LSN A;  1HXC A;  3KRO B;  5DIQ F;  2PS4 A;  2H8O A;  3ADZ A;  4KQ5 A;  4L2X F;  3ZMC A;  3N1W F;  3IPI A;  4NFI F;  3ACY A;  1KIZ A;  3ICN A;  3LVS A;  4JYX A;  2E8U A;  4KVD A;  2P1C A;  5IM1 A;  2FOR A;  2QIS A;  3BNY A;  3TFP A;  5IN8 A;  3DYH A;  4H5E F;  1VG6 A;  1VG7 A;  4KQU A;  3KRA B;  3WE9 A;  4KUX A;  4KVI A;  3M01 A;  5DJV F;  5ILH A;  2OPN A;  4P0V A;  2EWG A;  5IK6 A;  3N3L F;  1HX9 A;  3WCH A;  1FPS A;  1YYR A;  4JXN A;  2J1P A;  2Z4W A;  1V4E A;  4FJQ A;  2E8V A;  4FP4 A;  4H5D F;  2VF6 A;  2F94 F; 
#chains in the Genus database with same CATH topology
 3WCG A;  3VJ8 A;  3N0F A;  3ACW A;  4LZC A;  2ONH A;  3TC1 A;  5B01 A;  5B0J A;  3RYE A;  4LXW A;  5JV1 F;  5B0L A;  5IK9 A;  3WSA A;  2AEK A;  2E92 A;  3P41 A;  5B0I A;  5ILD A;  1V4I A;  3WJK A;  1YHM A;  3IBA A;  2Z4X A;  3V66 A;  3N3D A;  4GAX A;  3KBK A;  1ZW5 A;  5A0I A;  4GP1 A;  4P0W A;  5ERM A;  3WCF A;  5DGM F;  4NUA A;  2AEL A;  1YQ7 A;  1RTR A;  2F8Z F;  3WSB A;  4RNQ A;  4PVX F;  3WCJ A;  3N45 F;  2Z78 A;  3LJI A;  2PS8 A;  3WCE A;  3WEH A;  4LA6 A;  2I19 A;  4MC3 A;  1UBW A;  4LOB A;  4F62 A;  4MC8 A;  3ACX A;  2F92 F;  5HN8 A;  1YYT A;  4RYP A;  3KB9 A;  3M9U A;  2Z4V A;  3SDU A;  3LLW A;  3ICK A;  4QPF A;  4XQT F;  5HNA A;  5DGN F;  3B7L A;  3APZ A;  3ICM A;  3KRA A;  2F9K F;  2ZEU A;  3G4D A;  3WCM A;  2E90 A;  4KWD A;  3WCL A;  3BNX A;  1N20 A;  5IMP A;  3LGK A;  4LFV F;  1DI1 A;  5EAT A;  3QKC A;  3ZOU A;  4RXD A;  3WCB A;  3LDW A;  2Q9Y A;  3N1V F;  5H9D A;  5JA0 F;  1EZF A;  3EFQ A;  5IKH A;  1N23 A;  3N6K F;  2Q58 A;  4KKM A;  5IKA A;  5B0K A;  3V1X A;  1V4K A;  1WMW A;  1N24 A;  3AQB B;  2Z50 A;  2F89 F;  3N5H F;  1WL0 A;  3VJE A;  4KVW A;  4XQS F;  3P8R A;  4KFA A;  3Q2Q A;  4LA5 A;  5B03 A;  3PKO A;  3OYR A;  3Q2Z A;  1JFG A;  1HXG A;  5CG5 A;  3AQC B;  4OMH A;  2ZY1 A;  1N1B A;  4JZX A;  5CG6 A;  4F6V A;  3MZV A;  4UMJ A;  3ID0 A;  4JZB A;  4XQR F;  2Z7H A;  3SDT A;  3LZ9 A;  5AHU B;  2AET A;  3VJD A;  4PVY F;  2ZCO A;  5HN7 A;  4DWB A;  4DHD A;  4LLT A;  4QXS F;  4DWG A;  3KRP B;  3AE0 A;  3OAC B;  5HN9 A;  3WEK A;  5ERN A;  4EA0 A;  5ERO A;  3VJC A;  2DH4 A;  3P5R A;  5IL8 A;  2J5C A;  3SAE A;  3LEE A;  3PYA A;  1WL3 A;  4OKZ A;  2AZL A;  1YYU A;  5C05 A;  2PS6 A;  1WL1 A;  5JUZ F;  2O1O A;  4H5C F;  3RYW A;  5EAU A;  3VJA A;  2E95 A;  3M00 A;  4ZQ8 A;  4KPJ A;  1YJ4 A;  5DJR F;  3KRF A;  3LK5 A;  3WCD A;  4OMG A;  3NF2 A;  5DZ2 A;  5AYP A;  1PS1 A;  2RAH A;  2OPM A;  1WKZ A;  3TS7 A;  5IMI A;  4RXA A;  1VG2 A;  5ILI A;  4OKM A;  3DYF A;  5DGS F;  2ZCR A;  3ZMB A;  3WJO A;  4DEM F;  5IMN A;  2E94 A;  3S4J A;  3WEJ A;  3NPK A;  5ILY A;  2Q9Z A;  3PYB A;  5E8L A;  2Z7I A;  3RBM A;  4NKF A;  1YYQ A;  3CKE A;  3KRF B;  1YHK A;  1YYS A;  5IVG A;  5DW7 A;  4LZ0 A;  2E8X A;  4OGU A;  1VG3 A;  4LUU A;  3EGT A;  4LIX A;  3V1V A;  3WEI A;  2E8T A;  4WK5 A;  5IL3 A;  4JXY A;  3N5J F;  3N49 F;  2FTZ A;  2J1O A;  3SDR A;  1JFA A;  2ZCQ A;  5ILJ A;  4MC0 A;  3NRI A;  5AFX A;  4LPG F;  4LZ3 A;  2AZJ A;  4DZW A;  1N21 A;  3KRC A;  1YHL A;  3PDE A;  5DHK A;  3P8L A;  4EA1 A;  3KRP A;  3OAC A;  5A0K A;  5ILK A;  2E91 A;  1WL2 A;  1RQJ A;  4E9Z A;  3VJB A;  3WJN A;  3ZCD A;  4GP2 A;  3G4F A;  5DHI A;  4NFJ F;  3P5P A;  3WC9 A;  4LPH F;  3WCA A;  1HXA A;  1WY0 A;  1UBX A;  4E1E A;  5B02 A;  1RQI A;  3MAV A;  3NPR A;  1UBY A;  1UBV A;  3DYG A;  4KQS A;  2ONG A;  3SDQ A;  3KRC B;  5IK0 A;  4K10 A;  5DJP F;  2ZCS A;  1HM7 A;  4RXC A;  4NKE A;  4GA3 A;  4LLS A;  4DXJ A;  3LOM A;  5EAS A;  5JV2 F;  1KIY A;  2F8C F;  4LFE A;  4P0X A;  4LTZ A;  3WEG A;  4KVY A;  5KSX F;  4RXE A;  2OGD A;  2AZK A;  5I1U A;  2PS7 A;  3CP6 A;  3WCI A;  4LFG A;  3OAB A;  5A0J A;  4NFK F;  1DGP A;  5E8K A;  3TFN A;  4E9U A;  4LTV A;  3VJ9 A;  5B0M A;  5AEL A;  3M02 A;  3EZ3 A;  3LMD A;  3WEF A;  3RMG A;  4KPD A;  3ICZ A;  5ILZ A;  1N1Z A;  4N9U A;  4EA2 A;  5E8H A;  1V4H A;  4Q23 A;  2Q80 A;  4JVJ F;  3KRO A;  2ZEV A;  1V4J A;  1YV5 A;  2Z4Y A;  3N46 F;  4DI5 A;  5B00 A;  1HM4 A;  3LG5 A;  4NG6 A;  5ER8 A;  4F6X A;  3TFV A;  2PS5 A;  1N22 A;  3Q30 A;  4N1Z F;  3ZL6 A;  4KK2 A;  3LGZ B;  2Z4Z A;  4HD1 A;  3S9V A;  2E93 A;  3OAB B;  2F7M F;  3M0G A;  3UCA A;  3ASX A;  2E4O A;  2E8W A;  2Z52 A;  3CC9 A;  5JV0 F;  3W7F A;  2OA6 A;  3SDV A;  3AQ0 A;  3N0G A;  3QQV A;  3Q1O A;  3PH7 A;  3WCC A;  1VG4 A;  3LSN A;  1HXC A;  3KRO B;  5DIQ F;  2PS4 A;  2H8O A;  3ADZ A;  4KQ5 A;  4L2X F;  3ZMC A;  3N1W F;  3IPI A;  4NFI F;  3ACY A;  1KIZ A;  3ICN A;  3LVS A;  4JYX A;  2E8U A;  4KVD A;  2P1C A;  5IM1 A;  2FOR A;  2QIS A;  3BNY A;  3TFP A;  5IN8 A;  3DYH A;  4H5E F;  1VG6 A;  1VG7 A;  4KQU A;  3KRA B;  3WE9 A;  4KUX A;  4KVI A;  3M01 A;  5DJV F;  5ILH A;  2OPN A;  4P0V A;  2EWG A;  5IK6 A;  3N3L F;  1HX9 A;  3WCH A;  1FPS A;  1YYR A;  4JXN A;  2J1P A;  2Z4W A;  1V4E A;  4FJQ A;  2E8V A;  4FP4 A;  4H5D F;  2VF6 A;  2F94 F; 
#chains in the Genus database with same CATH homology
 3WCG A;  3VJ8 A;  3N0F A;  3ACW A;  4LZC A;  2ONH A;  3TC1 A;  5B01 A;  5B0J A;  3RYE A;  4LXW A;  5JV1 F;  5B0L A;  5IK9 A;  3WSA A;  2AEK A;  2E92 A;  3P41 A;  5B0I A;  5ILD A;  1V4I A;  3WJK A;  1YHM A;  3IBA A;  2Z4X A;  3V66 A;  3N3D A;  4GAX A;  3KBK A;  1ZW5 A;  5A0I A;  4GP1 A;  4P0W A;  5ERM A;  3WCF A;  5DGM F;  4NUA A;  2AEL A;  1YQ7 A;  1RTR A;  2F8Z F;  3WSB A;  4RNQ A;  4PVX F;  3WCJ A;  3N45 F;  2Z78 A;  3LJI A;  2PS8 A;  3WCE A;  3WEH A;  4LA6 A;  2I19 A;  4MC3 A;  1UBW A;  4LOB A;  4F62 A;  4MC8 A;  3ACX A;  2F92 F;  5HN8 A;  1YYT A;  4RYP A;  3KB9 A;  3M9U A;  2Z4V A;  3SDU A;  3LLW A;  3ICK A;  4QPF A;  4XQT F;  5HNA A;  5DGN F;  3B7L A;  3APZ A;  3ICM A;  3KRA A;  2F9K F;  2ZEU A;  3G4D A;  3WCM A;  2E90 A;  4KWD A;  3WCL A;  3BNX A;  1N20 A;  5IMP A;  3LGK A;  4LFV F;  1DI1 A;  5EAT A;  3QKC A;  3ZOU A;  4RXD A;  3WCB A;  3LDW A;  2Q9Y A;  3N1V F;  5H9D A;  5JA0 F;  1EZF A;  3EFQ A;  5IKH A;  1N23 A;  3N6K F;  2Q58 A;  4KKM A;  5IKA A;  5B0K A;  3V1X A;  1V4K A;  1WMW A;  1N24 A;  3AQB B;  2Z50 A;  2F89 F;  3N5H F;  1WL0 A;  3VJE A;  4KVW A;  4XQS F;  3P8R A;  4KFA A;  3Q2Q A;  4LA5 A;  5B03 A;  3PKO A;  3OYR A;  3Q2Z A;  1JFG A;  1HXG A;  5CG5 A;  3AQC B;  4OMH A;  2ZY1 A;  1N1B A;  4JZX A;  5CG6 A;  4F6V A;  3MZV A;  4UMJ A;  3ID0 A;  4JZB A;  4XQR F;  2Z7H A;  3SDT A;  3LZ9 A;  5AHU B;  2AET A;  3VJD A;  4PVY F;  2ZCO A;  5HN7 A;  4DWB A;  4DHD A;  4LLT A;  4QXS F;  4DWG A;  3KRP B;  3AE0 A;  3OAC B;  5HN9 A;  3WEK A;  5ERN A;  4EA0 A;  5ERO A;  3VJC A;  2DH4 A;  3P5R A;  5IL8 A;  2J5C A;  3SAE A;  3LEE A;  3PYA A;  1WL3 A;  4OKZ A;  2AZL A;  1YYU A;  5C05 A;  2PS6 A;  1WL1 A;  5JUZ F;  2O1O A;  4H5C F;  3RYW A;  5EAU A;  3VJA A;  2E95 A;  3M00 A;  4ZQ8 A;  4KPJ A;  1YJ4 A;  5DJR F;  3KRF A;  3LK5 A;  3WCD A;  4OMG A;  3NF2 A;  5DZ2 A;  5AYP A;  1PS1 A;  2RAH A;  2OPM A;  1WKZ A;  3TS7 A;  5IMI A;  4RXA A;  1VG2 A;  5ILI A;  4OKM A;  3DYF A;  5DGS F;  2ZCR A;  3ZMB A;  3WJO A;  4DEM F;  5IMN A;  2E94 A;  3S4J A;  3WEJ A;  3NPK A;  5ILY A;  2Q9Z A;  3PYB A;  5E8L A;  2Z7I A;  3RBM A;  4NKF A;  1YYQ A;  3CKE A;  3KRF B;  1YHK A;  1YYS A;  5IVG A;  5DW7 A;  4LZ0 A;  2E8X A;  4OGU A;  1VG3 A;  4LUU A;  3EGT A;  4LIX A;  3V1V A;  3WEI A;  2E8T A;  4WK5 A;  5IL3 A;  4JXY A;  3N5J F;  3N49 F;  2FTZ A;  2J1O A;  3SDR A;  1JFA A;  2ZCQ A;  5ILJ A;  4MC0 A;  3NRI A;  5AFX A;  4LPG F;  4LZ3 A;  2AZJ A;  4DZW A;  1N21 A;  3KRC A;  1YHL A;  3PDE A;  5DHK A;  3P8L A;  4EA1 A;  3KRP A;  3OAC A;  5A0K A;  5ILK A;  2E91 A;  1WL2 A;  1RQJ A;  4E9Z A;  3VJB A;  3WJN A;  3ZCD A;  4GP2 A;  3G4F A;  5DHI A;  4NFJ F;  3P5P A;  3WC9 A;  4LPH F;  3WCA A;  1HXA A;  1WY0 A;  1UBX A;  4E1E A;  5B02 A;  1RQI A;  3MAV A;  3NPR A;  1UBY A;  1UBV A;  3DYG A;  4KQS A;  2ONG A;  3SDQ A;  3KRC B;  5IK0 A;  4K10 A;  5DJP F;  2ZCS A;  1HM7 A;  4RXC A;  4NKE A;  4GA3 A;  4LLS A;  4DXJ A;  3LOM A;  5EAS A;  5JV2 F;  1KIY A;  2F8C F;  4LFE A;  4P0X A;  4LTZ A;  3WEG A;  4KVY A;  5KSX F;  4RXE A;  2OGD A;  2AZK A;  5I1U A;  2PS7 A;  3CP6 A;  3WCI A;  4LFG A;  3OAB A;  5A0J A;  4NFK F;  1DGP A;  5E8K A;  3TFN A;  4E9U A;  4LTV A;  3VJ9 A;  5B0M A;  5AEL A;  3M02 A;  3EZ3 A;  3LMD A;  3WEF A;  3RMG A;  4KPD A;  3ICZ A;  5ILZ A;  1N1Z A;  4N9U A;  4EA2 A;  5E8H A;  1V4H A;  4Q23 A;  2Q80 A;  4JVJ F;  3KRO A;  2ZEV A;  1V4J A;  1YV5 A;  2Z4Y A;  3N46 F;  4DI5 A;  5B00 A;  1HM4 A;  3LG5 A;  4NG6 A;  5ER8 A;  4F6X A;  3TFV A;  2PS5 A;  1N22 A;  3Q30 A;  4N1Z F;  3ZL6 A;  4KK2 A;  3LGZ B;  2Z4Z A;  4HD1 A;  3S9V A;  2E93 A;  3OAB B;  2F7M F;  3M0G A;  3UCA A;  3ASX A;  2E4O A;  2E8W A;  2Z52 A;  3CC9 A;  5JV0 F;  3W7F A;  2OA6 A;  3SDV A;  3AQ0 A;  3N0G A;  3QQV A;  3Q1O A;  3PH7 A;  3WCC A;  1VG4 A;  3LSN A;  1HXC A;  3KRO B;  5DIQ F;  2PS4 A;  2H8O A;  3ADZ A;  4KQ5 A;  4L2X F;  3ZMC A;  3N1W F;  3IPI A;  4NFI F;  3ACY A;  1KIZ A;  3ICN A;  3LVS A;  4JYX A;  2E8U A;  4KVD A;  2P1C A;  5IM1 A;  2FOR A;  2QIS A;  3BNY A;  3TFP A;  5IN8 A;  3DYH A;  4H5E F;  1VG6 A;  1VG7 A;  4KQU A;  3KRA B;  3WE9 A;  4KUX A;  4KVI A;  3M01 A;  5DJV F;  5ILH A;  2OPN A;  4P0V A;  2EWG A;  5IK6 A;  3N3L F;  1HX9 A;  3WCH A;  1FPS A;  1YYR A;  4JXN A;  2J1P A;  2Z4W A;  1V4E A;  4FJQ A;  2E8V A;  4FP4 A;  4H5D F;  2VF6 A;  2F94 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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