3EFQA

T. brucei farnesyl diphosphate synthase complexed with bisphosphonate bph-714
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
367
structure length
358
Chain Sequence
MPMQMFMQVYDEIQMFLLEELELKFDMDPNRVRYLRKMMDTTCLGGKYNRGLTVIDVAESLLSLDGARRKRVLHDACVCGWMIEFLQAHYLVEDDIMDNSVTRRGKPCWYRHPDVTVQCAINDGLLLKSWTHMMAMHFFADRPFLQDLLCRFNRVDYTTAVGQLYDVTSMFDSNKLDPDVSQPTTTDFAEFTLSNYKRIVKYKTAYYTYLLPLVMGLIVSEALPTVDMGVTEELAMLMGEYFQVQDDVMDCFTPPERLGKVGTDIQDAKCSWLAVTFLAKASSAQVAEFKANYGSGDSEKVATVRRLYEEADLQGDYVAYEAAVAEQVKELIEKLRLCSPGFAASVETLWGKTYKRQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma brucei
molecule keywords Farnesyl pyrophosphate synthase
total genus 147
structure length 358
sequence length 367
chains with identical sequence B
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2008-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3efqA00
3KRPB 3LK5A 1VG3A 5CG5A 3RMGA 3VJ8A 2J5CA 2PS4A 4KFAA 3ZMBA 2F7MF 3M9UA 2F8CF 4H5EF 4NFIF 4DWBA 1WL0A 5EROA 4QPFA 5AELA 3ZOUA 4LLSA 4OGUA 1RTRA 1UBVA 1YYTA 3AQCB 4GA3A 5AYPA 5E8HA 4NKFA 1WY0A 3M00A 2ZEUA 2J1OA 5IK0A 1N1ZA 2FORA 5ERNA 5E8LA 5CG6A 5B02A 5KSXF 3VJCA 4KQ5A 3M02A 4UMJA 4E1EA 5HNAA 1DI1A 1V4IA 4MC3A 2F9KF 1UBXA 1YQ7A 3M0GA 4RXDA 1VG7A 5DJVF 3CP6A 3OYRA 4KVIA 3WEHA 1UBYA 3KRCB 3SDRA 3EZ3A 5DJRF 5IKHA 3ICNA 3LDWA 1JFGA 1RQJA 1YV5A 3WCCA 2OPMA 4JZBA 2F8ZF 1N20A 1PS1A 3V1VA 3LOMA 2E90A 3PYAA 2OGDA 3Q2ZA 1V4HA 1WMWA 4OMGA 1KIZA 4RYPA 1N23A 3VJAA 4LA6A 3PYBA 2E92A 2Q9YA 5DGSF 2ONGA 4LOBA 3PKOA 2FTZA 5E8KA 5IL3A 3N0FA 4LTZA 3P5RA 4KPDA 4LLTA 3WEIA 3TC1A 4K10A 3BNYA 2E8VA 4DWGA 4NKEA 4KK2A 2Z7HA 3ZCDA 3WEGA 4QXSF 4NUAA 4LXWA 3LZ9A 3SAEA 3ZL6A 3ACWA 5JV0F 4JVJF 2F94F 2AELA 5B0IA 3EFQA 3LLWA 3ICMA 1YHKA 3LSNA 2Z78A 4LA5A 4FJQA 5A0JA 4LIXA 3ICKA 3AQBB 5IN8A 4OMHA 3TFPA 4KQUA 3N3DA 3ASXA 5DGNF 4E9ZA 4XQTF 3LVSA 3P41A 5DIQF 3SDUA 5A0KA 5DGMF 2PS5A 3WE9A 3QQVA 3ACYA 2PS6A 4GP2A 2Z4VA 1YYRA 4KPJA 1N21A 3LEEA 1WL3A 1YHMA 5JA0F 1RQIA 4GP1A 5B0MA 2F92F 2F89F 3WCFA 3SDVA 4H5CF 1N22A 3RYEA 5IKAA 3PH7A 4GAXA 3N46F 2E94A 2VF6A 5HN8A 2Z4YA 4JXNA 2E95A 1DGPA 3NRIA 4FP4A 3CC9A 4L2XF 5DZ2A 4LFGA 4DXJA 3Q1OA 5AHUB 4LPGF 3WJOA 3V1XA 3B7LA 5ILHA 4JXYA 5B0KA 5IK6A 3N5JF 4LZ0A 4PVYF 3WCBA 3OABA 1YYQA 5ILDA 4KWDA 4P0WA 4DI5A 5IVGA 2E8XA 2I19A 5C05A 3P5PA 1UBWA 3KRFA 3N49F 1HM4A 4NFJF 4ZQ8A 4NG6A 2AEKA 4LFVF 2ZCSA 4KVDA 3P8LA 5B0JA 4RNQA 4KQSA 4E9UA 4EA0A 2E8UA 4LTVA 2PS8A 3LGZB 1N24A 5EAUA 3WCGA 5ER8A 3RBMA 3G4DA 4HD1A 3KROA 3BNXA 1WL1A 1EZFA 4LFEA 5DHKA 5DJPF 4NFKF 5JUZF 3KRAB 4P0XA 3NPKA 2ZCQA 4N9UA 1WKZA 3WCDA 3Q30A 1N1BA 3LJIA 1YJ4A 3AE0A 5HN7A 4XQRF 2AZLA 1YHLA 2RAHA 5JV1F 1HXGA 3NF2A 3WJKA 3KRCA 3ADZA 3NPRA 3WEJA 2O1OA 3LGKA 3DYHA 4F6XA 4DEMF 1WL2A 3N6KF 5IL8A 3VJDA 2AZKA 3S9VA 2Z4WA 4MC8A 5H9DA 2PS7A 3OACA 3EGTA 3ICZA 2DH4A 4WK5A 4PVXF 3VJ9A 4KUXA 2ONHA 4F6VA 2AZJA 3N0GA 3P8RA 2ZEVA 1VG6A 4P0VA 5HN9A 2E91A 3N45F 2J1PA 2H8OA 3UCAA 5IMPA 5EATA 3ID0A 1FPSA 1VG4A 5B01A 1ZW5A 1HXAA 1HM7A 3WJNA 3LG5A 2Z4ZA 3TS7A 2EWGA 5B00A 3WEKA 2Q80A 3WCJA 3WCEA 4KVYA 3VJBA 5DHIA 3DYFA 3OABB 4LPHF 4LUUA 4N1ZF 3M01A 5IM1A 2ZY1A 3KRFB 5IMNA 1VG2A 2ZCRA 3KRPA 4LZCA 3WCLA 4OKMA 4JYXA 3KB9A 3WCAA 3WCHA 5ILJA 3TFVA 5ILKA 3MAVA 1HXCA 5IMIA 2OA6A 3IBAA 3N1WF 3APZA 2OPNA 2Q58A 4F62A 3G4FA 2Z50A 4XQSF 3KROB 3W7FA 4Q23A 2E8TA 4KKMA 4EA2A 2Z7IA 4EA1A 4JZXA 4RXAA 2Z52A 3S4JA 4LZ3A 1KIYA 5ILIA 4RXEA 4OKZA 5EASA 2P1CA 1HX9A 2E93A 5ERMA 3SDQA 5ILZA 3WEFA 5JV2F 4RXCA 5ILYA 1V4KA 3SDTA 1V4JA 3OACB 3ZMCA 1JFAA 4DZWA 3N1VF 2Q9ZA 2ZCOA 5AFXA 3WCIA 2QISA 2AETA 3QKCA 5DW7A 3TFNA 3CKEA 1YYUA 3IPIA 2E8WA 3N3LF 3VJEA 3PDEA 4DHDA 4MC0A 5A0IA 3DYGA 3LMDA 5B0LA 3KBKA 1YYSA 2E4OA 3WSBA 2Z4XA 3RYWA 5B03A 3KRAA 3MZVA 4KVWA 1V4EA 3WSAA 5I1UA 3Q2QA 3AQ0A 5IK9A 3WCMA 3N5HF 3WC9A 3V66A 3ACXA 4H5DF
chains in the Genus database with same CATH superfamily
3KRPB 3LK5A 1VG3A 5CG5A 3RMGA 3VJ8A 2J5CA 2PS4A 4KFAA 3ZMBA 2F7MF 3M9UA 2F8CF 4H5EF 4NFIF 4DWBA 1WL0A 5EROA 4QPFA 5AELA 3ZOUA 4LLSA 4OGUA 1RTRA 1UBVA 1YYTA 3AQCB 4GA3A 5AYPA 5E8HA 4NKFA 1WY0A 3M00A 2ZEUA 2J1OA 5IK0A 1N1ZA 2FORA 5ERNA 5E8LA 5CG6A 5B02A 5KSXF 3VJCA 4KQ5A 3M02A 4UMJA 4E1EA 5HNAA 1DI1A 1V4IA 4MC3A 2F9KF 1UBXA 1YQ7A 3M0GA 4RXDA 1VG7A 5DJVF 3CP6A 3OYRA 4KVIA 3WEHA 1UBYA 3KRCB 3SDRA 3EZ3A 5DJRF 5IKHA 3ICNA 3LDWA 1JFGA 1RQJA 1YV5A 3WCCA 2OPMA 4JZBA 2F8ZF 1N20A 1PS1A 3V1VA 3LOMA 2E90A 3PYAA 2OGDA 3Q2ZA 1V4HA 1WMWA 4OMGA 1KIZA 4RYPA 1N23A 3VJAA 4LA6A 3PYBA 2E92A 2Q9YA 5DGSF 2ONGA 4LOBA 3PKOA 2FTZA 5E8KA 5IL3A 3N0FA 4LTZA 3P5RA 4KPDA 4LLTA 3WEIA 3TC1A 4K10A 3BNYA 2E8VA 4DWGA 4NKEA 4KK2A 2Z7HA 3ZCDA 3WEGA 4QXSF 4NUAA 4LXWA 3LZ9A 3SAEA 3ZL6A 3ACWA 5JV0F 4JVJF 2F94F 2AELA 5B0IA 3EFQA 3LLWA 3ICMA 1YHKA 3LSNA 2Z78A 4LA5A 4FJQA 5A0JA 4LIXA 3ICKA 3AQBB 5IN8A 4OMHA 3TFPA 4KQUA 3N3DA 3ASXA 5DGNF 4E9ZA 4XQTF 3LVSA 3P41A 5DIQF 3SDUA 5A0KA 5DGMF 2PS5A 3WE9A 3QQVA 3ACYA 2PS6A 4GP2A 2Z4VA 1YYRA 4KPJA 1N21A 3LEEA 1WL3A 1YHMA 5JA0F 1RQIA 4GP1A 5B0MA 2F92F 2F89F 3WCFA 3SDVA 4H5CF 1N22A 3RYEA 5IKAA 3PH7A 4GAXA 3N46F 2E94A 2VF6A 5HN8A 2Z4YA 4JXNA 2E95A 1DGPA 3NRIA 4FP4A 3CC9A 4L2XF 5DZ2A 4LFGA 4DXJA 3Q1OA 5AHUB 4LPGF 3WJOA 3V1XA 3B7LA 5ILHA 4JXYA 5B0KA 5IK6A 3N5JF 4LZ0A 4PVYF 3WCBA 3OABA 1YYQA 5ILDA 4KWDA 4P0WA 4DI5A 5IVGA 2E8XA 2I19A 5C05A 3P5PA 1UBWA 3KRFA 3N49F 1HM4A 4NFJF 4ZQ8A 4NG6A 2AEKA 4LFVF 2ZCSA 4KVDA 3P8LA 5B0JA 4RNQA 4KQSA 4E9UA 4EA0A 2E8UA 4LTVA 2PS8A 3LGZB 1N24A 5EAUA 3WCGA 5ER8A 3RBMA 3G4DA 4HD1A 3KROA 3BNXA 1WL1A 1EZFA 4LFEA 5DHKA 5DJPF 4NFKF 5JUZF 3KRAB 4P0XA 3NPKA 2ZCQA 4N9UA 1WKZA 3WCDA 3Q30A 1N1BA 3LJIA 1YJ4A 3AE0A 5HN7A 4XQRF 2AZLA 1YHLA 2RAHA 5JV1F 1HXGA 3NF2A 3WJKA 3KRCA 3ADZA 3NPRA 3WEJA 2O1OA 3LGKA 3DYHA 4F6XA 4DEMF 1WL2A 3N6KF 5IL8A 3VJDA 2AZKA 3S9VA 2Z4WA 4MC8A 5H9DA 2PS7A 3OACA 3EGTA 3ICZA 2DH4A 4WK5A 4PVXF 3VJ9A 4KUXA 2ONHA 4F6VA 2AZJA 3N0GA 3P8RA 2ZEVA 1VG6A 4P0VA 5HN9A 2E91A 3N45F 2J1PA 2H8OA 3UCAA 5IMPA 5EATA 3ID0A 1FPSA 1VG4A 5B01A 1ZW5A 1HXAA 1HM7A 3WJNA 3LG5A 2Z4ZA 3TS7A 2EWGA 5B00A 3WEKA 2Q80A 3WCJA 3WCEA 4KVYA 3VJBA 5DHIA 3DYFA 3OABB 4LPHF 4LUUA 4N1ZF 3M01A 5IM1A 2ZY1A 3KRFB 5IMNA 1VG2A 2ZCRA 3KRPA 4LZCA 3WCLA 4OKMA 4JYXA 3KB9A 3WCAA 3WCHA 5ILJA 3TFVA 5ILKA 3MAVA 1HXCA 5IMIA 2OA6A 3IBAA 3N1WF 3APZA 2OPNA 2Q58A 4F62A 3G4FA 2Z50A 4XQSF 3KROB 3W7FA 4Q23A 2E8TA 4KKMA 4EA2A 2Z7IA 4EA1A 4JZXA 4RXAA 2Z52A 3S4JA 4LZ3A 1KIYA 5ILIA 4RXEA 4OKZA 5EASA 2P1CA 1HX9A 2E93A 5ERMA 3SDQA 5ILZA 3WEFA 5JV2F 4RXCA 5ILYA 1V4KA 3SDTA 1V4JA 3OACB 3ZMCA 1JFAA 4DZWA 3N1VF 2Q9ZA 2ZCOA 5AFXA 3WCIA 2QISA 2AETA 3QKCA 5DW7A 3TFNA 3CKEA 1YYUA 3IPIA 2E8WA 3N3LF 3VJEA 3PDEA 4DHDA 4MC0A 5A0IA 3DYGA 3LMDA 5B0LA 3KBKA 1YYSA 2E4OA 3WSBA 2Z4XA 3RYWA 5B03A 3KRAA 3MZVA 4KVWA 1V4EA 3WSAA 5I1UA 3Q2QA 3AQ0A 5IK9A 3WCMA 3N5HF 3WC9A 3V66A 3ACXA 4H5DF
chains in the Genus database with same CATH topology
3KRPB 3LK5A 1VG3A 5CG5A 3RMGA 3VJ8A 2J5CA 2PS4A 4KFAA 3ZMBA 2F7MF 3M9UA 2F8CF 4H5EF 4NFIF 4DWBA 1WL0A 5EROA 4QPFA 5AELA 3ZOUA 4LLSA 4OGUA 1RTRA 1UBVA 1YYTA 3AQCB 4GA3A 5AYPA 5E8HA 4NKFA 1WY0A 3M00A 2ZEUA 2J1OA 5IK0A 1N1ZA 2FORA 5ERNA 5E8LA 5CG6A 5B02A 5KSXF 3VJCA 4KQ5A 3M02A 4UMJA 4E1EA 5HNAA 1DI1A 1V4IA 4MC3A 2F9KF 1UBXA 1YQ7A 3M0GA 4RXDA 1VG7A 5DJVF 3CP6A 3OYRA 4KVIA 3WEHA 1UBYA 3KRCB 3SDRA 3EZ3A 5DJRF 5IKHA 3ICNA 3LDWA 1JFGA 1RQJA 1YV5A 3WCCA 2OPMA 4JZBA 2F8ZF 1N20A 1PS1A 3V1VA 3LOMA 2E90A 3PYAA 2OGDA 3Q2ZA 1V4HA 1WMWA 4OMGA 1KIZA 4RYPA 1N23A 3VJAA 4LA6A 3PYBA 2E92A 2Q9YA 5DGSF 2ONGA 4LOBA 3PKOA 2FTZA 5E8KA 5IL3A 3N0FA 4LTZA 3P5RA 4KPDA 4LLTA 3WEIA 3TC1A 4K10A 3BNYA 2E8VA 4DWGA 4NKEA 4KK2A 2Z7HA 3ZCDA 3WEGA 4QXSF 4NUAA 4LXWA 3LZ9A 3SAEA 3ZL6A 3ACWA 5JV0F 4JVJF 2F94F 2AELA 5B0IA 3EFQA 3LLWA 3ICMA 1YHKA 3LSNA 2Z78A 4LA5A 4FJQA 5A0JA 4LIXA 3ICKA 3AQBB 5IN8A 4OMHA 3TFPA 4KQUA 3N3DA 3ASXA 5DGNF 4E9ZA 4XQTF 3LVSA 3P41A 5DIQF 3SDUA 5A0KA 5DGMF 2PS5A 3WE9A 3QQVA 3ACYA 2PS6A 4GP2A 2Z4VA 1YYRA 4KPJA 1N21A 3LEEA 1WL3A 1YHMA 5JA0F 1RQIA 4GP1A 5B0MA 2F92F 2F89F 3WCFA 3SDVA 4H5CF 1N22A 3RYEA 5IKAA 3PH7A 4GAXA 3N46F 2E94A 2VF6A 5HN8A 2Z4YA 4JXNA 2E95A 1DGPA 3NRIA 4FP4A 3CC9A 4L2XF 5DZ2A 4LFGA 4DXJA 3Q1OA 5AHUB 4LPGF 3WJOA 3V1XA 3B7LA 5ILHA 4JXYA 5B0KA 5IK6A 3N5JF 4LZ0A 4PVYF 3WCBA 3OABA 1YYQA 5ILDA 4KWDA 4P0WA 4DI5A 5IVGA 2E8XA 2I19A 5C05A 3P5PA 1UBWA 3KRFA 3N49F 1HM4A 4NFJF 4ZQ8A 4NG6A 2AEKA 4LFVF 2ZCSA 4KVDA 3P8LA 5B0JA 4RNQA 4KQSA 4E9UA 4EA0A 2E8UA 4LTVA 2PS8A 3LGZB 1N24A 5EAUA 3WCGA 5ER8A 3RBMA 3G4DA 4HD1A 3KROA 3BNXA 1WL1A 1EZFA 4LFEA 5DHKA 5DJPF 4NFKF 5JUZF 3KRAB 4P0XA 3NPKA 2ZCQA 4N9UA 1WKZA 3WCDA 3Q30A 1N1BA 3LJIA 1YJ4A 3AE0A 5HN7A 4XQRF 2AZLA 1YHLA 2RAHA 5JV1F 1HXGA 3NF2A 3WJKA 3KRCA 3ADZA 3NPRA 3WEJA 2O1OA 3LGKA 3DYHA 4F6XA 4DEMF 1WL2A 3N6KF 5IL8A 3VJDA 2AZKA 3S9VA 2Z4WA 4MC8A 5H9DA 2PS7A 3OACA 3EGTA 3ICZA 2DH4A 4WK5A 4PVXF 3VJ9A 4KUXA 2ONHA 4F6VA 2AZJA 3N0GA 3P8RA 2ZEVA 1VG6A 4P0VA 5HN9A 2E91A 3N45F 2J1PA 2H8OA 3UCAA 5IMPA 5EATA 3ID0A 1FPSA 1VG4A 5B01A 1ZW5A 1HXAA 1HM7A 3WJNA 3LG5A 2Z4ZA 3TS7A 2EWGA 5B00A 3WEKA 2Q80A 3WCJA 3WCEA 4KVYA 3VJBA 5DHIA 3DYFA 3OABB 4LPHF 4LUUA 4N1ZF 3M01A 5IM1A 2ZY1A 3KRFB 5IMNA 1VG2A 2ZCRA 3KRPA 4LZCA 3WCLA 4OKMA 4JYXA 3KB9A 3WCAA 3WCHA 5ILJA 3TFVA 5ILKA 3MAVA 1HXCA 5IMIA 2OA6A 3IBAA 3N1WF 3APZA 2OPNA 2Q58A 4F62A 3G4FA 2Z50A 4XQSF 3KROB 3W7FA 4Q23A 2E8TA 4KKMA 4EA2A 2Z7IA 4EA1A 4JZXA 4RXAA 2Z52A 3S4JA 4LZ3A 1KIYA 5ILIA 4RXEA 4OKZA 5EASA 2P1CA 1HX9A 2E93A 5ERMA 3SDQA 5ILZA 3WEFA 5JV2F 4RXCA 5ILYA 1V4KA 3SDTA 1V4JA 3OACB 3ZMCA 1JFAA 4DZWA 3N1VF 2Q9ZA 2ZCOA 5AFXA 3WCIA 2QISA 2AETA 3QKCA 5DW7A 3TFNA 3CKEA 1YYUA 3IPIA 2E8WA 3N3LF 3VJEA 3PDEA 4DHDA 4MC0A 5A0IA 3DYGA 3LMDA 5B0LA 3KBKA 1YYSA 2E4OA 3WSBA 2Z4XA 3RYWA 5B03A 3KRAA 3MZVA 4KVWA 1V4EA 3WSAA 5I1UA 3Q2QA 3AQ0A 5IK9A 3WCMA 3N5HF 3WC9A 3V66A 3ACXA 4H5DF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KRP B;  3LK5 A;  1VG3 A;  5CG5 A;  3RMG A;  3VJ8 A;  2J5C A;  2PS4 A;  4KFA A;  3ZMB A;  2F7M F;  3M9U A;  2F8C F;  4H5E F;  4NFI F;  4DWB A;  1WL0 A;  5ERO A;  4QPF A;  5AEL A;  3ZOU A;  4LLS A;  4OGU A;  1RTR A;  1UBV A;  1YYT A;  3AQC B;  4GA3 A;  5AYP A;  5E8H A;  4NKF A;  1WY0 A;  3M00 A;  2ZEU A;  2J1O A;  5IK0 A;  1N1Z A;  2FOR A;  5ERN A;  5E8L A;  5CG6 A;  5B02 A;  5KSX F;  3VJC A;  4KQ5 A;  3M02 A;  4UMJ A;  4E1E A;  5HNA A;  1DI1 A;  1V4I A;  4MC3 A;  2F9K F;  1UBX A;  1YQ7 A;  3M0G A;  4RXD A;  1VG7 A;  5DJV F;  3CP6 A;  3OYR A;  4KVI A;  3WEH A;  1UBY A;  3KRC B;  3SDR A;  3EZ3 A;  5DJR F;  5IKH A;  3ICN A;  3LDW A;  1JFG A;  1RQJ A;  1YV5 A;  3WCC A;  2OPM A;  4JZB A;  2F8Z F;  1N20 A;  1PS1 A;  3V1V A;  3LOM A;  2E90 A;  3PYA A;  2OGD A;  3Q2Z A;  1V4H A;  1WMW A;  4OMG A;  1KIZ A;  4RYP A;  1N23 A;  3VJA A;  4LA6 A;  3PYB A;  2E92 A;  2Q9Y A;  5DGS F;  2ONG A;  4LOB A;  3PKO A;  2FTZ A;  5E8K A;  5IL3 A;  3N0F A;  4LTZ A;  3P5R A;  4KPD A;  4LLT A;  3WEI A;  3TC1 A;  4K10 A;  3BNY A;  2E8V A;  4DWG A;  4NKE A;  4KK2 A;  2Z7H A;  3ZCD A;  3WEG A;  4QXS F;  4NUA A;  4LXW A;  3LZ9 A;  3SAE A;  3ZL6 A;  3ACW A;  5JV0 F;  4JVJ F;  2F94 F;  2AEL A;  5B0I A;  3EFQ A;  3LLW A;  3ICM A;  1YHK A;  3LSN A;  2Z78 A;  4LA5 A;  4FJQ A;  5A0J A;  4LIX A;  3ICK A;  3AQB B;  5IN8 A;  4OMH A;  3TFP A;  4KQU A;  3N3D A;  3ASX A;  5DGN F;  4E9Z A;  4XQT F;  3LVS A;  3P41 A;  5DIQ F;  3SDU A;  5A0K A;  5DGM F;  2PS5 A;  3WE9 A;  3QQV A;  3ACY A;  2PS6 A;  4GP2 A;  2Z4V A;  1YYR A;  4KPJ A;  1N21 A;  3LEE A;  1WL3 A;  1YHM A;  5JA0 F;  1RQI A;  4GP1 A;  5B0M A;  2F92 F;  2F89 F;  3WCF A;  3SDV A;  4H5C F;  1N22 A;  3RYE A;  5IKA A;  3PH7 A;  4GAX A;  3N46 F;  2E94 A;  2VF6 A;  5HN8 A;  2Z4Y A;  4JXN A;  2E95 A;  1DGP A;  3NRI A;  4FP4 A;  3CC9 A;  4L2X F;  5DZ2 A;  4LFG A;  4DXJ A;  3Q1O A;  5AHU B;  4LPG F;  3WJO A;  3V1X A;  3B7L A;  5ILH A;  4JXY A;  5B0K A;  5IK6 A;  3N5J F;  4LZ0 A;  4PVY F;  3WCB A;  3OAB A;  1YYQ A;  5ILD A;  4KWD A;  4P0W A;  4DI5 A;  5IVG A;  2E8X A;  2I19 A;  5C05 A;  3P5P A;  1UBW A;  3KRF A;  3N49 F;  1HM4 A;  4NFJ F;  4ZQ8 A;  4NG6 A;  2AEK A;  4LFV F;  2ZCS A;  4KVD A;  3P8L A;  5B0J A;  4RNQ A;  4KQS A;  4E9U A;  4EA0 A;  2E8U A;  4LTV A;  2PS8 A;  3LGZ B;  1N24 A;  5EAU A;  3WCG A;  5ER8 A;  3RBM A;  3G4D A;  4HD1 A;  3KRO A;  3BNX A;  1WL1 A;  1EZF A;  4LFE A;  5DHK A;  5DJP F;  4NFK F;  5JUZ F;  3KRA B;  4P0X A;  3NPK A;  2ZCQ A;  4N9U A;  1WKZ A;  3WCD A;  3Q30 A;  1N1B A;  3LJI A;  1YJ4 A;  3AE0 A;  5HN7 A;  4XQR F;  2AZL A;  1YHL A;  2RAH A;  5JV1 F;  1HXG A;  3NF2 A;  3WJK A;  3KRC A;  3ADZ A;  3NPR A;  3WEJ A;  2O1O A;  3LGK A;  3DYH A;  4F6X A;  4DEM F;  1WL2 A;  3N6K F;  5IL8 A;  3VJD A;  2AZK A;  3S9V A;  2Z4W A;  4MC8 A;  5H9D A;  2PS7 A;  3OAC A;  3EGT A;  3ICZ A;  2DH4 A;  4WK5 A;  4PVX F;  3VJ9 A;  4KUX A;  2ONH A;  4F6V A;  2AZJ A;  3N0G A;  3P8R A;  2ZEV A;  1VG6 A;  4P0V A;  5HN9 A;  2E91 A;  3N45 F;  2J1P A;  2H8O A;  3UCA A;  5IMP A;  5EAT A;  3ID0 A;  1FPS A;  1VG4 A;  5B01 A;  1ZW5 A;  1HXA A;  1HM7 A;  3WJN A;  3LG5 A;  2Z4Z A;  3TS7 A;  2EWG A;  5B00 A;  3WEK A;  2Q80 A;  3WCJ A;  3WCE A;  4KVY A;  3VJB A;  5DHI A;  3DYF A;  3OAB B;  4LPH F;  4LUU A;  4N1Z F;  3M01 A;  5IM1 A;  2ZY1 A;  3KRF B;  5IMN A;  1VG2 A;  2ZCR A;  3KRP A;  4LZC A;  3WCL A;  4OKM A;  4JYX A;  3KB9 A;  3WCA A;  3WCH A;  5ILJ A;  3TFV A;  5ILK A;  3MAV A;  1HXC A;  5IMI A;  2OA6 A;  3IBA A;  3N1W F;  3APZ A;  2OPN A;  2Q58 A;  4F62 A;  3G4F A;  2Z50 A;  4XQS F;  3KRO B;  3W7F A;  4Q23 A;  2E8T A;  4KKM A;  4EA2 A;  2Z7I A;  4EA1 A;  4JZX A;  4RXA A;  2Z52 A;  3S4J A;  4LZ3 A;  1KIY A;  5ILI A;  4RXE A;  4OKZ A;  5EAS A;  2P1C A;  1HX9 A;  2E93 A;  5ERM A;  3SDQ A;  5ILZ A;  3WEF A;  5JV2 F;  4RXC A;  5ILY A;  1V4K A;  3SDT A;  1V4J A;  3OAC B;  3ZMC A;  1JFA A;  4DZW A;  3N1V F;  2Q9Z A;  2ZCO A;  5AFX A;  3WCI A;  2QIS A;  2AET A;  3QKC A;  5DW7 A;  3TFN A;  3CKE A;  1YYU A;  3IPI A;  2E8W A;  3N3L F;  3VJE A;  3PDE A;  4DHD A;  4MC0 A;  5A0I A;  3DYG A;  3LMD A;  5B0L A;  3KBK A;  1YYS A;  2E4O A;  3WSB A;  2Z4X A;  3RYW A;  5B03 A;  3KRA A;  3MZV A;  4KVW A;  1V4E A;  3WSA A;  5I1U A;  3Q2Q A;  3AQ0 A;  5IK9 A;  3WCM A;  3N5H F;  3WC9 A;  3V66 A;  3ACX A;  4H5D F; 
#chains in the Genus database with same CATH topology
 3KRP B;  3LK5 A;  1VG3 A;  5CG5 A;  3RMG A;  3VJ8 A;  2J5C A;  2PS4 A;  4KFA A;  3ZMB A;  2F7M F;  3M9U A;  2F8C F;  4H5E F;  4NFI F;  4DWB A;  1WL0 A;  5ERO A;  4QPF A;  5AEL A;  3ZOU A;  4LLS A;  4OGU A;  1RTR A;  1UBV A;  1YYT A;  3AQC B;  4GA3 A;  5AYP A;  5E8H A;  4NKF A;  1WY0 A;  3M00 A;  2ZEU A;  2J1O A;  5IK0 A;  1N1Z A;  2FOR A;  5ERN A;  5E8L A;  5CG6 A;  5B02 A;  5KSX F;  3VJC A;  4KQ5 A;  3M02 A;  4UMJ A;  4E1E A;  5HNA A;  1DI1 A;  1V4I A;  4MC3 A;  2F9K F;  1UBX A;  1YQ7 A;  3M0G A;  4RXD A;  1VG7 A;  5DJV F;  3CP6 A;  3OYR A;  4KVI A;  3WEH A;  1UBY A;  3KRC B;  3SDR A;  3EZ3 A;  5DJR F;  5IKH A;  3ICN A;  3LDW A;  1JFG A;  1RQJ A;  1YV5 A;  3WCC A;  2OPM A;  4JZB A;  2F8Z F;  1N20 A;  1PS1 A;  3V1V A;  3LOM A;  2E90 A;  3PYA A;  2OGD A;  3Q2Z A;  1V4H A;  1WMW A;  4OMG A;  1KIZ A;  4RYP A;  1N23 A;  3VJA A;  4LA6 A;  3PYB A;  2E92 A;  2Q9Y A;  5DGS F;  2ONG A;  4LOB A;  3PKO A;  2FTZ A;  5E8K A;  5IL3 A;  3N0F A;  4LTZ A;  3P5R A;  4KPD A;  4LLT A;  3WEI A;  3TC1 A;  4K10 A;  3BNY A;  2E8V A;  4DWG A;  4NKE A;  4KK2 A;  2Z7H A;  3ZCD A;  3WEG A;  4QXS F;  4NUA A;  4LXW A;  3LZ9 A;  3SAE A;  3ZL6 A;  3ACW A;  5JV0 F;  4JVJ F;  2F94 F;  2AEL A;  5B0I A;  3EFQ A;  3LLW A;  3ICM A;  1YHK A;  3LSN A;  2Z78 A;  4LA5 A;  4FJQ A;  5A0J A;  4LIX A;  3ICK A;  3AQB B;  5IN8 A;  4OMH A;  3TFP A;  4KQU A;  3N3D A;  3ASX A;  5DGN F;  4E9Z A;  4XQT F;  3LVS A;  3P41 A;  5DIQ F;  3SDU A;  5A0K A;  5DGM F;  2PS5 A;  3WE9 A;  3QQV A;  3ACY A;  2PS6 A;  4GP2 A;  2Z4V A;  1YYR A;  4KPJ A;  1N21 A;  3LEE A;  1WL3 A;  1YHM A;  5JA0 F;  1RQI A;  4GP1 A;  5B0M A;  2F92 F;  2F89 F;  3WCF A;  3SDV A;  4H5C F;  1N22 A;  3RYE A;  5IKA A;  3PH7 A;  4GAX A;  3N46 F;  2E94 A;  2VF6 A;  5HN8 A;  2Z4Y A;  4JXN A;  2E95 A;  1DGP A;  3NRI A;  4FP4 A;  3CC9 A;  4L2X F;  5DZ2 A;  4LFG A;  4DXJ A;  3Q1O A;  5AHU B;  4LPG F;  3WJO A;  3V1X A;  3B7L A;  5ILH A;  4JXY A;  5B0K A;  5IK6 A;  3N5J F;  4LZ0 A;  4PVY F;  3WCB A;  3OAB A;  1YYQ A;  5ILD A;  4KWD A;  4P0W A;  4DI5 A;  5IVG A;  2E8X A;  2I19 A;  5C05 A;  3P5P A;  1UBW A;  3KRF A;  3N49 F;  1HM4 A;  4NFJ F;  4ZQ8 A;  4NG6 A;  2AEK A;  4LFV F;  2ZCS A;  4KVD A;  3P8L A;  5B0J A;  4RNQ A;  4KQS A;  4E9U A;  4EA0 A;  2E8U A;  4LTV A;  2PS8 A;  3LGZ B;  1N24 A;  5EAU A;  3WCG A;  5ER8 A;  3RBM A;  3G4D A;  4HD1 A;  3KRO A;  3BNX A;  1WL1 A;  1EZF A;  4LFE A;  5DHK A;  5DJP F;  4NFK F;  5JUZ F;  3KRA B;  4P0X A;  3NPK A;  2ZCQ A;  4N9U A;  1WKZ A;  3WCD A;  3Q30 A;  1N1B A;  3LJI A;  1YJ4 A;  3AE0 A;  5HN7 A;  4XQR F;  2AZL A;  1YHL A;  2RAH A;  5JV1 F;  1HXG A;  3NF2 A;  3WJK A;  3KRC A;  3ADZ A;  3NPR A;  3WEJ A;  2O1O A;  3LGK A;  3DYH A;  4F6X A;  4DEM F;  1WL2 A;  3N6K F;  5IL8 A;  3VJD A;  2AZK A;  3S9V A;  2Z4W A;  4MC8 A;  5H9D A;  2PS7 A;  3OAC A;  3EGT A;  3ICZ A;  2DH4 A;  4WK5 A;  4PVX F;  3VJ9 A;  4KUX A;  2ONH A;  4F6V A;  2AZJ A;  3N0G A;  3P8R A;  2ZEV A;  1VG6 A;  4P0V A;  5HN9 A;  2E91 A;  3N45 F;  2J1P A;  2H8O A;  3UCA A;  5IMP A;  5EAT A;  3ID0 A;  1FPS A;  1VG4 A;  5B01 A;  1ZW5 A;  1HXA A;  1HM7 A;  3WJN A;  3LG5 A;  2Z4Z A;  3TS7 A;  2EWG A;  5B00 A;  3WEK A;  2Q80 A;  3WCJ A;  3WCE A;  4KVY A;  3VJB A;  5DHI A;  3DYF A;  3OAB B;  4LPH F;  4LUU A;  4N1Z F;  3M01 A;  5IM1 A;  2ZY1 A;  3KRF B;  5IMN A;  1VG2 A;  2ZCR A;  3KRP A;  4LZC A;  3WCL A;  4OKM A;  4JYX A;  3KB9 A;  3WCA A;  3WCH A;  5ILJ A;  3TFV A;  5ILK A;  3MAV A;  1HXC A;  5IMI A;  2OA6 A;  3IBA A;  3N1W F;  3APZ A;  2OPN A;  2Q58 A;  4F62 A;  3G4F A;  2Z50 A;  4XQS F;  3KRO B;  3W7F A;  4Q23 A;  2E8T A;  4KKM A;  4EA2 A;  2Z7I A;  4EA1 A;  4JZX A;  4RXA A;  2Z52 A;  3S4J A;  4LZ3 A;  1KIY A;  5ILI A;  4RXE A;  4OKZ A;  5EAS A;  2P1C A;  1HX9 A;  2E93 A;  5ERM A;  3SDQ A;  5ILZ A;  3WEF A;  5JV2 F;  4RXC A;  5ILY A;  1V4K A;  3SDT A;  1V4J A;  3OAC B;  3ZMC A;  1JFA A;  4DZW A;  3N1V F;  2Q9Z A;  2ZCO A;  5AFX A;  3WCI A;  2QIS A;  2AET A;  3QKC A;  5DW7 A;  3TFN A;  3CKE A;  1YYU A;  3IPI A;  2E8W A;  3N3L F;  3VJE A;  3PDE A;  4DHD A;  4MC0 A;  5A0I A;  3DYG A;  3LMD A;  5B0L A;  3KBK A;  1YYS A;  2E4O A;  3WSB A;  2Z4X A;  3RYW A;  5B03 A;  3KRA A;  3MZV A;  4KVW A;  1V4E A;  3WSA A;  5I1U A;  3Q2Q A;  3AQ0 A;  5IK9 A;  3WCM A;  3N5H F;  3WC9 A;  3V66 A;  3ACX A;  4H5D F; 
#chains in the Genus database with same CATH homology
 3KRP B;  3LK5 A;  1VG3 A;  5CG5 A;  3RMG A;  3VJ8 A;  2J5C A;  2PS4 A;  4KFA A;  3ZMB A;  2F7M F;  3M9U A;  2F8C F;  4H5E F;  4NFI F;  4DWB A;  1WL0 A;  5ERO A;  4QPF A;  5AEL A;  3ZOU A;  4LLS A;  4OGU A;  1RTR A;  1UBV A;  1YYT A;  3AQC B;  4GA3 A;  5AYP A;  5E8H A;  4NKF A;  1WY0 A;  3M00 A;  2ZEU A;  2J1O A;  5IK0 A;  1N1Z A;  2FOR A;  5ERN A;  5E8L A;  5CG6 A;  5B02 A;  5KSX F;  3VJC A;  4KQ5 A;  3M02 A;  4UMJ A;  4E1E A;  5HNA A;  1DI1 A;  1V4I A;  4MC3 A;  2F9K F;  1UBX A;  1YQ7 A;  3M0G A;  4RXD A;  1VG7 A;  5DJV F;  3CP6 A;  3OYR A;  4KVI A;  3WEH A;  1UBY A;  3KRC B;  3SDR A;  3EZ3 A;  5DJR F;  5IKH A;  3ICN A;  3LDW A;  1JFG A;  1RQJ A;  1YV5 A;  3WCC A;  2OPM A;  4JZB A;  2F8Z F;  1N20 A;  1PS1 A;  3V1V A;  3LOM A;  2E90 A;  3PYA A;  2OGD A;  3Q2Z A;  1V4H A;  1WMW A;  4OMG A;  1KIZ A;  4RYP A;  1N23 A;  3VJA A;  4LA6 A;  3PYB A;  2E92 A;  2Q9Y A;  5DGS F;  2ONG A;  4LOB A;  3PKO A;  2FTZ A;  5E8K A;  5IL3 A;  3N0F A;  4LTZ A;  3P5R A;  4KPD A;  4LLT A;  3WEI A;  3TC1 A;  4K10 A;  3BNY A;  2E8V A;  4DWG A;  4NKE A;  4KK2 A;  2Z7H A;  3ZCD A;  3WEG A;  4QXS F;  4NUA A;  4LXW A;  3LZ9 A;  3SAE A;  3ZL6 A;  3ACW A;  5JV0 F;  4JVJ F;  2F94 F;  2AEL A;  5B0I A;  3EFQ A;  3LLW A;  3ICM A;  1YHK A;  3LSN A;  2Z78 A;  4LA5 A;  4FJQ A;  5A0J A;  4LIX A;  3ICK A;  3AQB B;  5IN8 A;  4OMH A;  3TFP A;  4KQU A;  3N3D A;  3ASX A;  5DGN F;  4E9Z A;  4XQT F;  3LVS A;  3P41 A;  5DIQ F;  3SDU A;  5A0K A;  5DGM F;  2PS5 A;  3WE9 A;  3QQV A;  3ACY A;  2PS6 A;  4GP2 A;  2Z4V A;  1YYR A;  4KPJ A;  1N21 A;  3LEE A;  1WL3 A;  1YHM A;  5JA0 F;  1RQI A;  4GP1 A;  5B0M A;  2F92 F;  2F89 F;  3WCF A;  3SDV A;  4H5C F;  1N22 A;  3RYE A;  5IKA A;  3PH7 A;  4GAX A;  3N46 F;  2E94 A;  2VF6 A;  5HN8 A;  2Z4Y A;  4JXN A;  2E95 A;  1DGP A;  3NRI A;  4FP4 A;  3CC9 A;  4L2X F;  5DZ2 A;  4LFG A;  4DXJ A;  3Q1O A;  5AHU B;  4LPG F;  3WJO A;  3V1X A;  3B7L A;  5ILH A;  4JXY A;  5B0K A;  5IK6 A;  3N5J F;  4LZ0 A;  4PVY F;  3WCB A;  3OAB A;  1YYQ A;  5ILD A;  4KWD A;  4P0W A;  4DI5 A;  5IVG A;  2E8X A;  2I19 A;  5C05 A;  3P5P A;  1UBW A;  3KRF A;  3N49 F;  1HM4 A;  4NFJ F;  4ZQ8 A;  4NG6 A;  2AEK A;  4LFV F;  2ZCS A;  4KVD A;  3P8L A;  5B0J A;  4RNQ A;  4KQS A;  4E9U A;  4EA0 A;  2E8U A;  4LTV A;  2PS8 A;  3LGZ B;  1N24 A;  5EAU A;  3WCG A;  5ER8 A;  3RBM A;  3G4D A;  4HD1 A;  3KRO A;  3BNX A;  1WL1 A;  1EZF A;  4LFE A;  5DHK A;  5DJP F;  4NFK F;  5JUZ F;  3KRA B;  4P0X A;  3NPK A;  2ZCQ A;  4N9U A;  1WKZ A;  3WCD A;  3Q30 A;  1N1B A;  3LJI A;  1YJ4 A;  3AE0 A;  5HN7 A;  4XQR F;  2AZL A;  1YHL A;  2RAH A;  5JV1 F;  1HXG A;  3NF2 A;  3WJK A;  3KRC A;  3ADZ A;  3NPR A;  3WEJ A;  2O1O A;  3LGK A;  3DYH A;  4F6X A;  4DEM F;  1WL2 A;  3N6K F;  5IL8 A;  3VJD A;  2AZK A;  3S9V A;  2Z4W A;  4MC8 A;  5H9D A;  2PS7 A;  3OAC A;  3EGT A;  3ICZ A;  2DH4 A;  4WK5 A;  4PVX F;  3VJ9 A;  4KUX A;  2ONH A;  4F6V A;  2AZJ A;  3N0G A;  3P8R A;  2ZEV A;  1VG6 A;  4P0V A;  5HN9 A;  2E91 A;  3N45 F;  2J1P A;  2H8O A;  3UCA A;  5IMP A;  5EAT A;  3ID0 A;  1FPS A;  1VG4 A;  5B01 A;  1ZW5 A;  1HXA A;  1HM7 A;  3WJN A;  3LG5 A;  2Z4Z A;  3TS7 A;  2EWG A;  5B00 A;  3WEK A;  2Q80 A;  3WCJ A;  3WCE A;  4KVY A;  3VJB A;  5DHI A;  3DYF A;  3OAB B;  4LPH F;  4LUU A;  4N1Z F;  3M01 A;  5IM1 A;  2ZY1 A;  3KRF B;  5IMN A;  1VG2 A;  2ZCR A;  3KRP A;  4LZC A;  3WCL A;  4OKM A;  4JYX A;  3KB9 A;  3WCA A;  3WCH A;  5ILJ A;  3TFV A;  5ILK A;  3MAV A;  1HXC A;  5IMI A;  2OA6 A;  3IBA A;  3N1W F;  3APZ A;  2OPN A;  2Q58 A;  4F62 A;  3G4F A;  2Z50 A;  4XQS F;  3KRO B;  3W7F A;  4Q23 A;  2E8T A;  4KKM A;  4EA2 A;  2Z7I A;  4EA1 A;  4JZX A;  4RXA A;  2Z52 A;  3S4J A;  4LZ3 A;  1KIY A;  5ILI A;  4RXE A;  4OKZ A;  5EAS A;  2P1C A;  1HX9 A;  2E93 A;  5ERM A;  3SDQ A;  5ILZ A;  3WEF A;  5JV2 F;  4RXC A;  5ILY A;  1V4K A;  3SDT A;  1V4J A;  3OAC B;  3ZMC A;  1JFA A;  4DZW A;  3N1V F;  2Q9Z A;  2ZCO A;  5AFX A;  3WCI A;  2QIS A;  2AET A;  3QKC A;  5DW7 A;  3TFN A;  3CKE A;  1YYU A;  3IPI A;  2E8W A;  3N3L F;  3VJE A;  3PDE A;  4DHD A;  4MC0 A;  5A0I A;  3DYG A;  3LMD A;  5B0L A;  3KBK A;  1YYS A;  2E4O A;  3WSB A;  2Z4X A;  3RYW A;  5B03 A;  3KRA A;  3MZV A;  4KVW A;  1V4E A;  3WSA A;  5I1U A;  3Q2Q A;  3AQ0 A;  5IK9 A;  3WCM A;  3N5H F;  3WC9 A;  3V66 A;  3ACX A;  4H5D F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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