3ICMA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate, mg2+ and 1-(2-hydroxy-2,2-bis-phosphono-ethyl)-3-phenyl-pyridinium
Total Genus 146
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
146
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords Farnesyl pyrophosphate synthase
total genus 146
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icmA00
1YYTA 2EWGA 1WMWA 3TFVA 3SDUA 3PDEA 3AQBB 2E94A 3AQCB 3G4FA 3OYRA 3N5HF 5DGMF 3WCFA 2E4OA 3ASXA 5IVGA 4KQUA 4KVWA 4JVJF 4RXAA 4DWGA 2E8XA 1V4HA 5ERNA 4E9UA 5CG5A 2Z7IA 1WL3A 5ILHA 3BNYA 3WEJA 4RYPA 3P8LA 4LLSA 5DZ2A 4RXDA 2E95A 4JYXA 3LK5A 3TFPA 3WEIA 2AZLA 5JV2F 3QKCA 5EROA 1V4KA 5JV1F 1YYQA 2Z52A 4NFKF 4KPDA 2F89F 2Z50A 3WCHA 3KRCA 3LVSA 2AELA 1YHKA 3LGZB 5A0JA 3Q2QA 3V1VA 4NKFA 5ILIA 3N1VF 3P5RA 1HM7A 4FJQA 2I19A 3LJIA 4LFVF 5B0LA 1WL2A 3Q1OA 2E90A 3ICNA 3KROB 4MC8A 5IMNA 5IL8A 3N6KF 4PVXF 4NUAA 4H5DF 4LIXA 3OABB 3ZL6A 4DWBA 5A0IA 3TC1A 1UBVA 5IN8A 3LLWA 3DYFA 4OGUA 3SAEA 1RQJA 3N1WF 5ILYA 4XQTF 3PKOA 4LA5A 5JV0F 1YJ4A 4KVYA 3RBMA 3WCMA 4JZBA 3ID0A 4F6VA 3M9UA 5DIQF 3WEHA 3V1XA 4KK2A 3RYWA 5AELA 3KRFB 3CKEA 3WSBA 4XQSF 1YV5A 3KRCB 3NPKA 2Q80A 4KVDA 5JA0F 3WJOA 2ONGA 4RXEA 3LMDA 3N0GA 4OMHA 5B0KA 5C05A 3S4JA 2VF6A 3OACA 5IKAA 3CP6A 4NFIF 3LZ9A 4KVIA 3VJCA 4DEMF 3S9VA 4E1EA 3VJAA 1N21A 2J1PA 4KQSA 3RYEA 3LOMA 4KWDA 2Z78A 1WL0A 4KPJA 5IMPA 4EA0A 1V4JA 3WJNA 3N49F 5DJPF 5IL3A 4QXSF 3N5JF 3WEKA 2OGDA 2E8WA 2F8ZF 4LZCA 4NFJF 1N20A 4F62A 3VJ9A 3N3DA 1N1BA 5B02A 3WCGA 2OPNA 3NPRA 5ER8A 1WKZA 1HXGA 1VG4A 5DJRF 5JUZF 5EASA 2Z4YA 2AEKA 5DGSF 3P5PA 4PVYF 5ILKA 3DYGA 4KKMA 5IK0A 3KRPB 4LPHF 3WC9A 3EGTA 2AZJA 4P0WA 2F8CF 4RNQA 3N46F 5DJVF 3OACB 5E8KA 1HXAA 1RQIA 3UCAA 4EA1A 2Z4ZA 3DYHA 4XQRF 4JZXA 4KUXA 2E8VA 4E9ZA 4JXYA 4DI5A 2PS8A 3KRAA 5IKHA 2OPMA 5KSXF 1YYRA 5B0JA 2PS5A 4MC3A 3KBKA 2DH4A 5IK6A 4GP1A 1YYUA 5A0KA 5B0IA 4GP2A 5B03A 2OA6A 1HXCA 3ICZA 3QQVA 2ZEVA 1N24A 3ACWA 4NG6A 2ONHA 3LGKA 3G4DA 3N3LF 3CC9A 3WCJA 1N22A 5CG6A 5EATA 3WCEA 1WL1A 4LFGA 1VG6A 4HD1A 4KFAA 3WCBA 3TFNA 4H5CF 5ILZA 2PS6A 5AFXA 2PS4A 1HX9A 2J5CA 4LFEA 1YHLA 2Q9ZA 3N45F 2Z4VA 5AHUB 4DHDA 2F9KF 2J1OA 4OKMA 5H9DA 3PYAA 3RMGA 1FPSA 1PS1A 2H8OA 1V4EA 2ZY1A 2PS7A 2ZCOA 1JFAA 4OMGA 3LG5A 1UBYA 3AQ0A 3ACYA 4ZQ8A 4WK5A 5ILJA 5HNAA 5DHKA 3M02A 2ZCQA 2F92F 1YQ7A 2ZEUA 3ZOUA 4MC0A 5E8LA 5DGNF 3WEFA 3BNXA 4LA6A 1UBWA 3WEGA 3WCCA 3Q30A 2Z7HA 1HM4A 4GAXA 5DW7A 5B00A 3ZMCA 3VJBA 5ILDA 3ACXA 3KROA 5I1UA 5HN8A 3LEEA 3ZCDA 1YYSA 3WJKA 4LXWA 2Z4WA 1V4IA 4NKEA 1VG3A 2Q58A 3KB9A 3M0GA 3OABA 4DXJA 5ERMA 1VG2A 3W7FA 3WSAA 2FTZA 3MAVA 3NF2A 4LPGF 3SDQA 5IM1A 3P8RA 2RAHA 5IK9A 1DGPA 4LLTA 4RXCA 4H5EF 3WCDA 1JFGA 4K10A 4L2XF 1ZW5A 1EZFA 2F7MF 3M01A 3IPIA 4P0XA 1N1ZA 3AE0A 5B01A 2FORA 5DHIA 4EA2A 3N0FA 3KRFA 3ZMBA 1N23A 3LSNA 1YHMA 2P1CA 1KIZA 4Q23A 3VJEA 3SDTA 5IMIA 4KQ5A 4OKZA 4P0VA 4JXNA 3TS7A 3Q2ZA 3NRIA 2E92A 3P41A 4F6XA 3VJ8A 4FP4A 3MZVA 5AYPA 2E91A 2ZCSA 4QPFA 3APZA 3ICKA 3EZ3A 3V66A 3ICMA 4N1ZF 3PYBA 3WCIA 4LTZA 4LOBA 5HN9A 3ADZA 3VJDA 3WE9A 4N9UA 2ZCRA 1WY0A 3B7LA 2AZKA 3EFQA 2E93A 1RTRA 3LDWA 3SDRA 2F94F 2Z4XA 3WCAA 2Q9YA 5HN7A 4LZ0A 1KIYA 2E8UA 3M00A 4UMJA 4DZWA 3KRAB 3KRPA 2QISA 2E8TA 5E8HA 5B0MA 1UBXA 2O1OA 5EAUA 4LUUA 3SDVA 3IBAA 1DI1A 4LZ3A 2AETA 3WCLA 4GA3A 3PH7A 1VG7A 4LTVA
chains in the Genus database with same CATH superfamily
1YYTA 2EWGA 1WMWA 3TFVA 3SDUA 3PDEA 3AQBB 2E94A 3AQCB 3G4FA 3OYRA 3N5HF 5DGMF 3WCFA 2E4OA 3ASXA 5IVGA 4KQUA 4KVWA 4JVJF 4RXAA 4DWGA 2E8XA 1V4HA 5ERNA 4E9UA 5CG5A 2Z7IA 1WL3A 5ILHA 3BNYA 3WEJA 4RYPA 3P8LA 4LLSA 5DZ2A 4RXDA 2E95A 4JYXA 3LK5A 3TFPA 3WEIA 2AZLA 5JV2F 3QKCA 5EROA 1V4KA 5JV1F 1YYQA 2Z52A 4NFKF 4KPDA 2F89F 2Z50A 3WCHA 3KRCA 3LVSA 2AELA 1YHKA 3LGZB 5A0JA 3Q2QA 3V1VA 4NKFA 5ILIA 3N1VF 3P5RA 1HM7A 4FJQA 2I19A 3LJIA 4LFVF 5B0LA 1WL2A 3Q1OA 2E90A 3ICNA 3KROB 4MC8A 5IMNA 5IL8A 3N6KF 4PVXF 4NUAA 4H5DF 4LIXA 3OABB 3ZL6A 4DWBA 5A0IA 3TC1A 1UBVA 5IN8A 3LLWA 3DYFA 4OGUA 3SAEA 1RQJA 3N1WF 5ILYA 4XQTF 3PKOA 4LA5A 5JV0F 1YJ4A 4KVYA 3RBMA 3WCMA 4JZBA 3ID0A 4F6VA 3M9UA 5DIQF 3WEHA 3V1XA 4KK2A 3RYWA 5AELA 3KRFB 3CKEA 3WSBA 4XQSF 1YV5A 3KRCB 3NPKA 2Q80A 4KVDA 5JA0F 3WJOA 2ONGA 4RXEA 3LMDA 3N0GA 4OMHA 5B0KA 5C05A 3S4JA 2VF6A 3OACA 5IKAA 3CP6A 4NFIF 3LZ9A 4KVIA 3VJCA 4DEMF 3S9VA 4E1EA 3VJAA 1N21A 2J1PA 4KQSA 3RYEA 3LOMA 4KWDA 2Z78A 1WL0A 4KPJA 5IMPA 4EA0A 1V4JA 3WJNA 3N49F 5DJPF 5IL3A 4QXSF 3N5JF 3WEKA 2OGDA 2E8WA 2F8ZF 4LZCA 4NFJF 1N20A 4F62A 3VJ9A 3N3DA 1N1BA 5B02A 3WCGA 2OPNA 3NPRA 5ER8A 1WKZA 1HXGA 1VG4A 5DJRF 5JUZF 5EASA 2Z4YA 2AEKA 5DGSF 3P5PA 4PVYF 5ILKA 3DYGA 4KKMA 5IK0A 3KRPB 4LPHF 3WC9A 3EGTA 2AZJA 4P0WA 2F8CF 4RNQA 3N46F 5DJVF 3OACB 5E8KA 1HXAA 1RQIA 3UCAA 4EA1A 2Z4ZA 3DYHA 4XQRF 4JZXA 4KUXA 2E8VA 4E9ZA 4JXYA 4DI5A 2PS8A 3KRAA 5IKHA 2OPMA 5KSXF 1YYRA 5B0JA 2PS5A 4MC3A 3KBKA 2DH4A 5IK6A 4GP1A 1YYUA 5A0KA 5B0IA 4GP2A 5B03A 2OA6A 1HXCA 3ICZA 3QQVA 2ZEVA 1N24A 3ACWA 4NG6A 2ONHA 3LGKA 3G4DA 3N3LF 3CC9A 3WCJA 1N22A 5CG6A 5EATA 3WCEA 1WL1A 4LFGA 1VG6A 4HD1A 4KFAA 3WCBA 3TFNA 4H5CF 5ILZA 2PS6A 5AFXA 2PS4A 1HX9A 2J5CA 4LFEA 1YHLA 2Q9ZA 3N45F 2Z4VA 5AHUB 4DHDA 2F9KF 2J1OA 4OKMA 5H9DA 3PYAA 3RMGA 1FPSA 1PS1A 2H8OA 1V4EA 2ZY1A 2PS7A 2ZCOA 1JFAA 4OMGA 3LG5A 1UBYA 3AQ0A 3ACYA 4ZQ8A 4WK5A 5ILJA 5HNAA 5DHKA 3M02A 2ZCQA 2F92F 1YQ7A 2ZEUA 3ZOUA 4MC0A 5E8LA 5DGNF 3WEFA 3BNXA 4LA6A 1UBWA 3WEGA 3WCCA 3Q30A 2Z7HA 1HM4A 4GAXA 5DW7A 5B00A 3ZMCA 3VJBA 5ILDA 3ACXA 3KROA 5I1UA 5HN8A 3LEEA 3ZCDA 1YYSA 3WJKA 4LXWA 2Z4WA 1V4IA 4NKEA 1VG3A 2Q58A 3KB9A 3M0GA 3OABA 4DXJA 5ERMA 1VG2A 3W7FA 3WSAA 2FTZA 3MAVA 3NF2A 4LPGF 3SDQA 5IM1A 3P8RA 2RAHA 5IK9A 1DGPA 4LLTA 4RXCA 4H5EF 3WCDA 1JFGA 4K10A 4L2XF 1ZW5A 1EZFA 2F7MF 3M01A 3IPIA 4P0XA 1N1ZA 3AE0A 5B01A 2FORA 5DHIA 4EA2A 3N0FA 3KRFA 3ZMBA 1N23A 3LSNA 1YHMA 2P1CA 1KIZA 4Q23A 3VJEA 3SDTA 5IMIA 4KQ5A 4OKZA 4P0VA 4JXNA 3TS7A 3Q2ZA 3NRIA 2E92A 3P41A 4F6XA 3VJ8A 4FP4A 3MZVA 5AYPA 2E91A 2ZCSA 4QPFA 3APZA 3ICKA 3EZ3A 3V66A 3ICMA 4N1ZF 3PYBA 3WCIA 4LTZA 4LOBA 5HN9A 3ADZA 3VJDA 3WE9A 4N9UA 2ZCRA 1WY0A 3B7LA 2AZKA 3EFQA 2E93A 1RTRA 3LDWA 3SDRA 2F94F 2Z4XA 3WCAA 2Q9YA 5HN7A 4LZ0A 1KIYA 2E8UA 3M00A 4UMJA 4DZWA 3KRAB 3KRPA 2QISA 2E8TA 5E8HA 5B0MA 1UBXA 2O1OA 5EAUA 4LUUA 3SDVA 3IBAA 1DI1A 4LZ3A 2AETA 3WCLA 4GA3A 3PH7A 1VG7A 4LTVA
chains in the Genus database with same CATH topology
1YYTA 2EWGA 1WMWA 3TFVA 3SDUA 3PDEA 3AQBB 2E94A 3AQCB 3G4FA 3OYRA 3N5HF 5DGMF 3WCFA 2E4OA 3ASXA 5IVGA 4KQUA 4KVWA 4JVJF 4RXAA 4DWGA 2E8XA 1V4HA 5ERNA 4E9UA 5CG5A 2Z7IA 1WL3A 5ILHA 3BNYA 3WEJA 4RYPA 3P8LA 4LLSA 5DZ2A 4RXDA 2E95A 4JYXA 3LK5A 3TFPA 3WEIA 2AZLA 5JV2F 3QKCA 5EROA 1V4KA 5JV1F 1YYQA 2Z52A 4NFKF 4KPDA 2F89F 2Z50A 3WCHA 3KRCA 3LVSA 2AELA 1YHKA 3LGZB 5A0JA 3Q2QA 3V1VA 4NKFA 5ILIA 3N1VF 3P5RA 1HM7A 4FJQA 2I19A 3LJIA 4LFVF 5B0LA 1WL2A 3Q1OA 2E90A 3ICNA 3KROB 4MC8A 5IMNA 5IL8A 3N6KF 4PVXF 4NUAA 4H5DF 4LIXA 3OABB 3ZL6A 4DWBA 5A0IA 3TC1A 1UBVA 5IN8A 3LLWA 3DYFA 4OGUA 3SAEA 1RQJA 3N1WF 5ILYA 4XQTF 3PKOA 4LA5A 5JV0F 1YJ4A 4KVYA 3RBMA 3WCMA 4JZBA 3ID0A 4F6VA 3M9UA 5DIQF 3WEHA 3V1XA 4KK2A 3RYWA 5AELA 3KRFB 3CKEA 3WSBA 4XQSF 1YV5A 3KRCB 3NPKA 2Q80A 4KVDA 5JA0F 3WJOA 2ONGA 4RXEA 3LMDA 3N0GA 4OMHA 5B0KA 5C05A 3S4JA 2VF6A 3OACA 5IKAA 3CP6A 4NFIF 3LZ9A 4KVIA 3VJCA 4DEMF 3S9VA 4E1EA 3VJAA 1N21A 2J1PA 4KQSA 3RYEA 3LOMA 4KWDA 2Z78A 1WL0A 4KPJA 5IMPA 4EA0A 1V4JA 3WJNA 3N49F 5DJPF 5IL3A 4QXSF 3N5JF 3WEKA 2OGDA 2E8WA 2F8ZF 4LZCA 4NFJF 1N20A 4F62A 3VJ9A 3N3DA 1N1BA 5B02A 3WCGA 2OPNA 3NPRA 5ER8A 1WKZA 1HXGA 1VG4A 5DJRF 5JUZF 5EASA 2Z4YA 2AEKA 5DGSF 3P5PA 4PVYF 5ILKA 3DYGA 4KKMA 5IK0A 3KRPB 4LPHF 3WC9A 3EGTA 2AZJA 4P0WA 2F8CF 4RNQA 3N46F 5DJVF 3OACB 5E8KA 1HXAA 1RQIA 3UCAA 4EA1A 2Z4ZA 3DYHA 4XQRF 4JZXA 4KUXA 2E8VA 4E9ZA 4JXYA 4DI5A 2PS8A 3KRAA 5IKHA 2OPMA 5KSXF 1YYRA 5B0JA 2PS5A 4MC3A 3KBKA 2DH4A 5IK6A 4GP1A 1YYUA 5A0KA 5B0IA 4GP2A 5B03A 2OA6A 1HXCA 3ICZA 3QQVA 2ZEVA 1N24A 3ACWA 4NG6A 2ONHA 3LGKA 3G4DA 3N3LF 3CC9A 3WCJA 1N22A 5CG6A 5EATA 3WCEA 1WL1A 4LFGA 1VG6A 4HD1A 4KFAA 3WCBA 3TFNA 4H5CF 5ILZA 2PS6A 5AFXA 2PS4A 1HX9A 2J5CA 4LFEA 1YHLA 2Q9ZA 3N45F 2Z4VA 5AHUB 4DHDA 2F9KF 2J1OA 4OKMA 5H9DA 3PYAA 3RMGA 1FPSA 1PS1A 2H8OA 1V4EA 2ZY1A 2PS7A 2ZCOA 1JFAA 4OMGA 3LG5A 1UBYA 3AQ0A 3ACYA 4ZQ8A 4WK5A 5ILJA 5HNAA 5DHKA 3M02A 2ZCQA 2F92F 1YQ7A 2ZEUA 3ZOUA 4MC0A 5E8LA 5DGNF 3WEFA 3BNXA 4LA6A 1UBWA 3WEGA 3WCCA 3Q30A 2Z7HA 1HM4A 4GAXA 5DW7A 5B00A 3ZMCA 3VJBA 5ILDA 3ACXA 3KROA 5I1UA 5HN8A 3LEEA 3ZCDA 1YYSA 3WJKA 4LXWA 2Z4WA 1V4IA 4NKEA 1VG3A 2Q58A 3KB9A 3M0GA 3OABA 4DXJA 5ERMA 1VG2A 3W7FA 3WSAA 2FTZA 3MAVA 3NF2A 4LPGF 3SDQA 5IM1A 3P8RA 2RAHA 5IK9A 1DGPA 4LLTA 4RXCA 4H5EF 3WCDA 1JFGA 4K10A 4L2XF 1ZW5A 1EZFA 2F7MF 3M01A 3IPIA 4P0XA 1N1ZA 3AE0A 5B01A 2FORA 5DHIA 4EA2A 3N0FA 3KRFA 3ZMBA 1N23A 3LSNA 1YHMA 2P1CA 1KIZA 4Q23A 3VJEA 3SDTA 5IMIA 4KQ5A 4OKZA 4P0VA 4JXNA 3TS7A 3Q2ZA 3NRIA 2E92A 3P41A 4F6XA 3VJ8A 4FP4A 3MZVA 5AYPA 2E91A 2ZCSA 4QPFA 3APZA 3ICKA 3EZ3A 3V66A 3ICMA 4N1ZF 3PYBA 3WCIA 4LTZA 4LOBA 5HN9A 3ADZA 3VJDA 3WE9A 4N9UA 2ZCRA 1WY0A 3B7LA 2AZKA 3EFQA 2E93A 1RTRA 3LDWA 3SDRA 2F94F 2Z4XA 3WCAA 2Q9YA 5HN7A 4LZ0A 1KIYA 2E8UA 3M00A 4UMJA 4DZWA 3KRAB 3KRPA 2QISA 2E8TA 5E8HA 5B0MA 1UBXA 2O1OA 5EAUA 4LUUA 3SDVA 3IBAA 1DI1A 4LZ3A 2AETA 3WCLA 4GA3A 3PH7A 1VG7A 4LTVA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1YYT A;  2EWG A;  1WMW A;  3TFV A;  3SDU A;  3PDE A;  3AQB B;  2E94 A;  3AQC B;  3G4F A;  3OYR A;  3N5H F;  5DGM F;  3WCF A;  2E4O A;  3ASX A;  5IVG A;  4KQU A;  4KVW A;  4JVJ F;  4RXA A;  4DWG A;  2E8X A;  1V4H A;  5ERN A;  4E9U A;  5CG5 A;  2Z7I A;  1WL3 A;  5ILH A;  3BNY A;  3WEJ A;  4RYP A;  3P8L A;  4LLS A;  5DZ2 A;  4RXD A;  2E95 A;  4JYX A;  3LK5 A;  3TFP A;  3WEI A;  2AZL A;  5JV2 F;  3QKC A;  5ERO A;  1V4K A;  5JV1 F;  1YYQ A;  2Z52 A;  4NFK F;  4KPD A;  2F89 F;  2Z50 A;  3WCH A;  3KRC A;  3LVS A;  2AEL A;  1YHK A;  3LGZ B;  5A0J A;  3Q2Q A;  3V1V A;  4NKF A;  5ILI A;  3N1V F;  3P5R A;  1HM7 A;  4FJQ A;  2I19 A;  3LJI A;  4LFV F;  5B0L A;  1WL2 A;  3Q1O A;  2E90 A;  3ICN A;  3KRO B;  4MC8 A;  5IMN A;  5IL8 A;  3N6K F;  4PVX F;  4NUA A;  4H5D F;  4LIX A;  3OAB B;  3ZL6 A;  4DWB A;  5A0I A;  3TC1 A;  1UBV A;  5IN8 A;  3LLW A;  3DYF A;  4OGU A;  3SAE A;  1RQJ A;  3N1W F;  5ILY A;  4XQT F;  3PKO A;  4LA5 A;  5JV0 F;  1YJ4 A;  4KVY A;  3RBM A;  3WCM A;  4JZB A;  3ID0 A;  4F6V A;  3M9U A;  5DIQ F;  3WEH A;  3V1X A;  4KK2 A;  3RYW A;  5AEL A;  3KRF B;  3CKE A;  3WSB A;  4XQS F;  1YV5 A;  3KRC B;  3NPK A;  2Q80 A;  4KVD A;  5JA0 F;  3WJO A;  2ONG A;  4RXE A;  3LMD A;  3N0G A;  4OMH A;  5B0K A;  5C05 A;  3S4J A;  2VF6 A;  3OAC A;  5IKA A;  3CP6 A;  4NFI F;  3LZ9 A;  4KVI A;  3VJC A;  4DEM F;  3S9V A;  4E1E A;  3VJA A;  1N21 A;  2J1P A;  4KQS A;  3RYE A;  3LOM A;  4KWD A;  2Z78 A;  1WL0 A;  4KPJ A;  5IMP A;  4EA0 A;  1V4J A;  3WJN A;  3N49 F;  5DJP F;  5IL3 A;  4QXS F;  3N5J F;  3WEK A;  2OGD A;  2E8W A;  2F8Z F;  4LZC A;  4NFJ F;  1N20 A;  4F62 A;  3VJ9 A;  3N3D A;  1N1B A;  5B02 A;  3WCG A;  2OPN A;  3NPR A;  5ER8 A;  1WKZ A;  1HXG A;  1VG4 A;  5DJR F;  5JUZ F;  5EAS A;  2Z4Y A;  2AEK A;  5DGS F;  3P5P A;  4PVY F;  5ILK A;  3DYG A;  4KKM A;  5IK0 A;  3KRP B;  4LPH F;  3WC9 A;  3EGT A;  2AZJ A;  4P0W A;  2F8C F;  4RNQ A;  3N46 F;  5DJV F;  3OAC B;  5E8K A;  1HXA A;  1RQI A;  3UCA A;  4EA1 A;  2Z4Z A;  3DYH A;  4XQR F;  4JZX A;  4KUX A;  2E8V A;  4E9Z A;  4JXY A;  4DI5 A;  2PS8 A;  3KRA A;  5IKH A;  2OPM A;  5KSX F;  1YYR A;  5B0J A;  2PS5 A;  4MC3 A;  3KBK A;  2DH4 A;  5IK6 A;  4GP1 A;  1YYU A;  5A0K A;  5B0I A;  4GP2 A;  5B03 A;  2OA6 A;  1HXC A;  3ICZ A;  3QQV A;  2ZEV A;  1N24 A;  3ACW A;  4NG6 A;  2ONH A;  3LGK A;  3G4D A;  3N3L F;  3CC9 A;  3WCJ A;  1N22 A;  5CG6 A;  5EAT A;  3WCE A;  1WL1 A;  4LFG A;  1VG6 A;  4HD1 A;  4KFA A;  3WCB A;  3TFN A;  4H5C F;  5ILZ A;  2PS6 A;  5AFX A;  2PS4 A;  1HX9 A;  2J5C A;  4LFE A;  1YHL A;  2Q9Z A;  3N45 F;  2Z4V A;  5AHU B;  4DHD A;  2F9K F;  2J1O A;  4OKM A;  5H9D A;  3PYA A;  3RMG A;  1FPS A;  1PS1 A;  2H8O A;  1V4E A;  2ZY1 A;  2PS7 A;  2ZCO A;  1JFA A;  4OMG A;  3LG5 A;  1UBY A;  3AQ0 A;  3ACY A;  4ZQ8 A;  4WK5 A;  5ILJ A;  5HNA A;  5DHK A;  3M02 A;  2ZCQ A;  2F92 F;  1YQ7 A;  2ZEU A;  3ZOU A;  4MC0 A;  5E8L A;  5DGN F;  3WEF A;  3BNX A;  4LA6 A;  1UBW A;  3WEG A;  3WCC A;  3Q30 A;  2Z7H A;  1HM4 A;  4GAX A;  5DW7 A;  5B00 A;  3ZMC A;  3VJB A;  5ILD A;  3ACX A;  3KRO A;  5I1U A;  5HN8 A;  3LEE A;  3ZCD A;  1YYS A;  3WJK A;  4LXW A;  2Z4W A;  1V4I A;  4NKE A;  1VG3 A;  2Q58 A;  3KB9 A;  3M0G A;  3OAB A;  4DXJ A;  5ERM A;  1VG2 A;  3W7F A;  3WSA A;  2FTZ A;  3MAV A;  3NF2 A;  4LPG F;  3SDQ A;  5IM1 A;  3P8R A;  2RAH A;  5IK9 A;  1DGP A;  4LLT A;  4RXC A;  4H5E F;  3WCD A;  1JFG A;  4K10 A;  4L2X F;  1ZW5 A;  1EZF A;  2F7M F;  3M01 A;  3IPI A;  4P0X A;  1N1Z A;  3AE0 A;  5B01 A;  2FOR A;  5DHI A;  4EA2 A;  3N0F A;  3KRF A;  3ZMB A;  1N23 A;  3LSN A;  1YHM A;  2P1C A;  1KIZ A;  4Q23 A;  3VJE A;  3SDT A;  5IMI A;  4KQ5 A;  4OKZ A;  4P0V A;  4JXN A;  3TS7 A;  3Q2Z A;  3NRI A;  2E92 A;  3P41 A;  4F6X A;  3VJ8 A;  4FP4 A;  3MZV A;  5AYP A;  2E91 A;  2ZCS A;  4QPF A;  3APZ A;  3ICK A;  3EZ3 A;  3V66 A;  3ICM A;  4N1Z F;  3PYB A;  3WCI A;  4LTZ A;  4LOB A;  5HN9 A;  3ADZ A;  3VJD A;  3WE9 A;  4N9U A;  2ZCR A;  1WY0 A;  3B7L A;  2AZK A;  3EFQ A;  2E93 A;  1RTR A;  3LDW A;  3SDR A;  2F94 F;  2Z4X A;  3WCA A;  2Q9Y A;  5HN7 A;  4LZ0 A;  1KIY A;  2E8U A;  3M00 A;  4UMJ A;  4DZW A;  3KRA B;  3KRP A;  2QIS A;  2E8T A;  5E8H A;  5B0M A;  1UBX A;  2O1O A;  5EAU A;  4LUU A;  3SDV A;  3IBA A;  1DI1 A;  4LZ3 A;  2AET A;  3WCL A;  4GA3 A;  3PH7 A;  1VG7 A;  4LTV A; 
#chains in the Genus database with same CATH topology
 1YYT A;  2EWG A;  1WMW A;  3TFV A;  3SDU A;  3PDE A;  3AQB B;  2E94 A;  3AQC B;  3G4F A;  3OYR A;  3N5H F;  5DGM F;  3WCF A;  2E4O A;  3ASX A;  5IVG A;  4KQU A;  4KVW A;  4JVJ F;  4RXA A;  4DWG A;  2E8X A;  1V4H A;  5ERN A;  4E9U A;  5CG5 A;  2Z7I A;  1WL3 A;  5ILH A;  3BNY A;  3WEJ A;  4RYP A;  3P8L A;  4LLS A;  5DZ2 A;  4RXD A;  2E95 A;  4JYX A;  3LK5 A;  3TFP A;  3WEI A;  2AZL A;  5JV2 F;  3QKC A;  5ERO A;  1V4K A;  5JV1 F;  1YYQ A;  2Z52 A;  4NFK F;  4KPD A;  2F89 F;  2Z50 A;  3WCH A;  3KRC A;  3LVS A;  2AEL A;  1YHK A;  3LGZ B;  5A0J A;  3Q2Q A;  3V1V A;  4NKF A;  5ILI A;  3N1V F;  3P5R A;  1HM7 A;  4FJQ A;  2I19 A;  3LJI A;  4LFV F;  5B0L A;  1WL2 A;  3Q1O A;  2E90 A;  3ICN A;  3KRO B;  4MC8 A;  5IMN A;  5IL8 A;  3N6K F;  4PVX F;  4NUA A;  4H5D F;  4LIX A;  3OAB B;  3ZL6 A;  4DWB A;  5A0I A;  3TC1 A;  1UBV A;  5IN8 A;  3LLW A;  3DYF A;  4OGU A;  3SAE A;  1RQJ A;  3N1W F;  5ILY A;  4XQT F;  3PKO A;  4LA5 A;  5JV0 F;  1YJ4 A;  4KVY A;  3RBM A;  3WCM A;  4JZB A;  3ID0 A;  4F6V A;  3M9U A;  5DIQ F;  3WEH A;  3V1X A;  4KK2 A;  3RYW A;  5AEL A;  3KRF B;  3CKE A;  3WSB A;  4XQS F;  1YV5 A;  3KRC B;  3NPK A;  2Q80 A;  4KVD A;  5JA0 F;  3WJO A;  2ONG A;  4RXE A;  3LMD A;  3N0G A;  4OMH A;  5B0K A;  5C05 A;  3S4J A;  2VF6 A;  3OAC A;  5IKA A;  3CP6 A;  4NFI F;  3LZ9 A;  4KVI A;  3VJC A;  4DEM F;  3S9V A;  4E1E A;  3VJA A;  1N21 A;  2J1P A;  4KQS A;  3RYE A;  3LOM A;  4KWD A;  2Z78 A;  1WL0 A;  4KPJ A;  5IMP A;  4EA0 A;  1V4J A;  3WJN A;  3N49 F;  5DJP F;  5IL3 A;  4QXS F;  3N5J F;  3WEK A;  2OGD A;  2E8W A;  2F8Z F;  4LZC A;  4NFJ F;  1N20 A;  4F62 A;  3VJ9 A;  3N3D A;  1N1B A;  5B02 A;  3WCG A;  2OPN A;  3NPR A;  5ER8 A;  1WKZ A;  1HXG A;  1VG4 A;  5DJR F;  5JUZ F;  5EAS A;  2Z4Y A;  2AEK A;  5DGS F;  3P5P A;  4PVY F;  5ILK A;  3DYG A;  4KKM A;  5IK0 A;  3KRP B;  4LPH F;  3WC9 A;  3EGT A;  2AZJ A;  4P0W A;  2F8C F;  4RNQ A;  3N46 F;  5DJV F;  3OAC B;  5E8K A;  1HXA A;  1RQI A;  3UCA A;  4EA1 A;  2Z4Z A;  3DYH A;  4XQR F;  4JZX A;  4KUX A;  2E8V A;  4E9Z A;  4JXY A;  4DI5 A;  2PS8 A;  3KRA A;  5IKH A;  2OPM A;  5KSX F;  1YYR A;  5B0J A;  2PS5 A;  4MC3 A;  3KBK A;  2DH4 A;  5IK6 A;  4GP1 A;  1YYU A;  5A0K A;  5B0I A;  4GP2 A;  5B03 A;  2OA6 A;  1HXC A;  3ICZ A;  3QQV A;  2ZEV A;  1N24 A;  3ACW A;  4NG6 A;  2ONH A;  3LGK A;  3G4D A;  3N3L F;  3CC9 A;  3WCJ A;  1N22 A;  5CG6 A;  5EAT A;  3WCE A;  1WL1 A;  4LFG A;  1VG6 A;  4HD1 A;  4KFA A;  3WCB A;  3TFN A;  4H5C F;  5ILZ A;  2PS6 A;  5AFX A;  2PS4 A;  1HX9 A;  2J5C A;  4LFE A;  1YHL A;  2Q9Z A;  3N45 F;  2Z4V A;  5AHU B;  4DHD A;  2F9K F;  2J1O A;  4OKM A;  5H9D A;  3PYA A;  3RMG A;  1FPS A;  1PS1 A;  2H8O A;  1V4E A;  2ZY1 A;  2PS7 A;  2ZCO A;  1JFA A;  4OMG A;  3LG5 A;  1UBY A;  3AQ0 A;  3ACY A;  4ZQ8 A;  4WK5 A;  5ILJ A;  5HNA A;  5DHK A;  3M02 A;  2ZCQ A;  2F92 F;  1YQ7 A;  2ZEU A;  3ZOU A;  4MC0 A;  5E8L A;  5DGN F;  3WEF A;  3BNX A;  4LA6 A;  1UBW A;  3WEG A;  3WCC A;  3Q30 A;  2Z7H A;  1HM4 A;  4GAX A;  5DW7 A;  5B00 A;  3ZMC A;  3VJB A;  5ILD A;  3ACX A;  3KRO A;  5I1U A;  5HN8 A;  3LEE A;  3ZCD A;  1YYS A;  3WJK A;  4LXW A;  2Z4W A;  1V4I A;  4NKE A;  1VG3 A;  2Q58 A;  3KB9 A;  3M0G A;  3OAB A;  4DXJ A;  5ERM A;  1VG2 A;  3W7F A;  3WSA A;  2FTZ A;  3MAV A;  3NF2 A;  4LPG F;  3SDQ A;  5IM1 A;  3P8R A;  2RAH A;  5IK9 A;  1DGP A;  4LLT A;  4RXC A;  4H5E F;  3WCD A;  1JFG A;  4K10 A;  4L2X F;  1ZW5 A;  1EZF A;  2F7M F;  3M01 A;  3IPI A;  4P0X A;  1N1Z A;  3AE0 A;  5B01 A;  2FOR A;  5DHI A;  4EA2 A;  3N0F A;  3KRF A;  3ZMB A;  1N23 A;  3LSN A;  1YHM A;  2P1C A;  1KIZ A;  4Q23 A;  3VJE A;  3SDT A;  5IMI A;  4KQ5 A;  4OKZ A;  4P0V A;  4JXN A;  3TS7 A;  3Q2Z A;  3NRI A;  2E92 A;  3P41 A;  4F6X A;  3VJ8 A;  4FP4 A;  3MZV A;  5AYP A;  2E91 A;  2ZCS A;  4QPF A;  3APZ A;  3ICK A;  3EZ3 A;  3V66 A;  3ICM A;  4N1Z F;  3PYB A;  3WCI A;  4LTZ A;  4LOB A;  5HN9 A;  3ADZ A;  3VJD A;  3WE9 A;  4N9U A;  2ZCR A;  1WY0 A;  3B7L A;  2AZK A;  3EFQ A;  2E93 A;  1RTR A;  3LDW A;  3SDR A;  2F94 F;  2Z4X A;  3WCA A;  2Q9Y A;  5HN7 A;  4LZ0 A;  1KIY A;  2E8U A;  3M00 A;  4UMJ A;  4DZW A;  3KRA B;  3KRP A;  2QIS A;  2E8T A;  5E8H A;  5B0M A;  1UBX A;  2O1O A;  5EAU A;  4LUU A;  3SDV A;  3IBA A;  1DI1 A;  4LZ3 A;  2AET A;  3WCL A;  4GA3 A;  3PH7 A;  1VG7 A;  4LTV A; 
#chains in the Genus database with same CATH homology
 1YYT A;  2EWG A;  1WMW A;  3TFV A;  3SDU A;  3PDE A;  3AQB B;  2E94 A;  3AQC B;  3G4F A;  3OYR A;  3N5H F;  5DGM F;  3WCF A;  2E4O A;  3ASX A;  5IVG A;  4KQU A;  4KVW A;  4JVJ F;  4RXA A;  4DWG A;  2E8X A;  1V4H A;  5ERN A;  4E9U A;  5CG5 A;  2Z7I A;  1WL3 A;  5ILH A;  3BNY A;  3WEJ A;  4RYP A;  3P8L A;  4LLS A;  5DZ2 A;  4RXD A;  2E95 A;  4JYX A;  3LK5 A;  3TFP A;  3WEI A;  2AZL A;  5JV2 F;  3QKC A;  5ERO A;  1V4K A;  5JV1 F;  1YYQ A;  2Z52 A;  4NFK F;  4KPD A;  2F89 F;  2Z50 A;  3WCH A;  3KRC A;  3LVS A;  2AEL A;  1YHK A;  3LGZ B;  5A0J A;  3Q2Q A;  3V1V A;  4NKF A;  5ILI A;  3N1V F;  3P5R A;  1HM7 A;  4FJQ A;  2I19 A;  3LJI A;  4LFV F;  5B0L A;  1WL2 A;  3Q1O A;  2E90 A;  3ICN A;  3KRO B;  4MC8 A;  5IMN A;  5IL8 A;  3N6K F;  4PVX F;  4NUA A;  4H5D F;  4LIX A;  3OAB B;  3ZL6 A;  4DWB A;  5A0I A;  3TC1 A;  1UBV A;  5IN8 A;  3LLW A;  3DYF A;  4OGU A;  3SAE A;  1RQJ A;  3N1W F;  5ILY A;  4XQT F;  3PKO A;  4LA5 A;  5JV0 F;  1YJ4 A;  4KVY A;  3RBM A;  3WCM A;  4JZB A;  3ID0 A;  4F6V A;  3M9U A;  5DIQ F;  3WEH A;  3V1X A;  4KK2 A;  3RYW A;  5AEL A;  3KRF B;  3CKE A;  3WSB A;  4XQS F;  1YV5 A;  3KRC B;  3NPK A;  2Q80 A;  4KVD A;  5JA0 F;  3WJO A;  2ONG A;  4RXE A;  3LMD A;  3N0G A;  4OMH A;  5B0K A;  5C05 A;  3S4J A;  2VF6 A;  3OAC A;  5IKA A;  3CP6 A;  4NFI F;  3LZ9 A;  4KVI A;  3VJC A;  4DEM F;  3S9V A;  4E1E A;  3VJA A;  1N21 A;  2J1P A;  4KQS A;  3RYE A;  3LOM A;  4KWD A;  2Z78 A;  1WL0 A;  4KPJ A;  5IMP A;  4EA0 A;  1V4J A;  3WJN A;  3N49 F;  5DJP F;  5IL3 A;  4QXS F;  3N5J F;  3WEK A;  2OGD A;  2E8W A;  2F8Z F;  4LZC A;  4NFJ F;  1N20 A;  4F62 A;  3VJ9 A;  3N3D A;  1N1B A;  5B02 A;  3WCG A;  2OPN A;  3NPR A;  5ER8 A;  1WKZ A;  1HXG A;  1VG4 A;  5DJR F;  5JUZ F;  5EAS A;  2Z4Y A;  2AEK A;  5DGS F;  3P5P A;  4PVY F;  5ILK A;  3DYG A;  4KKM A;  5IK0 A;  3KRP B;  4LPH F;  3WC9 A;  3EGT A;  2AZJ A;  4P0W A;  2F8C F;  4RNQ A;  3N46 F;  5DJV F;  3OAC B;  5E8K A;  1HXA A;  1RQI A;  3UCA A;  4EA1 A;  2Z4Z A;  3DYH A;  4XQR F;  4JZX A;  4KUX A;  2E8V A;  4E9Z A;  4JXY A;  4DI5 A;  2PS8 A;  3KRA A;  5IKH A;  2OPM A;  5KSX F;  1YYR A;  5B0J A;  2PS5 A;  4MC3 A;  3KBK A;  2DH4 A;  5IK6 A;  4GP1 A;  1YYU A;  5A0K A;  5B0I A;  4GP2 A;  5B03 A;  2OA6 A;  1HXC A;  3ICZ A;  3QQV A;  2ZEV A;  1N24 A;  3ACW A;  4NG6 A;  2ONH A;  3LGK A;  3G4D A;  3N3L F;  3CC9 A;  3WCJ A;  1N22 A;  5CG6 A;  5EAT A;  3WCE A;  1WL1 A;  4LFG A;  1VG6 A;  4HD1 A;  4KFA A;  3WCB A;  3TFN A;  4H5C F;  5ILZ A;  2PS6 A;  5AFX A;  2PS4 A;  1HX9 A;  2J5C A;  4LFE A;  1YHL A;  2Q9Z A;  3N45 F;  2Z4V A;  5AHU B;  4DHD A;  2F9K F;  2J1O A;  4OKM A;  5H9D A;  3PYA A;  3RMG A;  1FPS A;  1PS1 A;  2H8O A;  1V4E A;  2ZY1 A;  2PS7 A;  2ZCO A;  1JFA A;  4OMG A;  3LG5 A;  1UBY A;  3AQ0 A;  3ACY A;  4ZQ8 A;  4WK5 A;  5ILJ A;  5HNA A;  5DHK A;  3M02 A;  2ZCQ A;  2F92 F;  1YQ7 A;  2ZEU A;  3ZOU A;  4MC0 A;  5E8L A;  5DGN F;  3WEF A;  3BNX A;  4LA6 A;  1UBW A;  3WEG A;  3WCC A;  3Q30 A;  2Z7H A;  1HM4 A;  4GAX A;  5DW7 A;  5B00 A;  3ZMC A;  3VJB A;  5ILD A;  3ACX A;  3KRO A;  5I1U A;  5HN8 A;  3LEE A;  3ZCD A;  1YYS A;  3WJK A;  4LXW A;  2Z4W A;  1V4I A;  4NKE A;  1VG3 A;  2Q58 A;  3KB9 A;  3M0G A;  3OAB A;  4DXJ A;  5ERM A;  1VG2 A;  3W7F A;  3WSA A;  2FTZ A;  3MAV A;  3NF2 A;  4LPG F;  3SDQ A;  5IM1 A;  3P8R A;  2RAH A;  5IK9 A;  1DGP A;  4LLT A;  4RXC A;  4H5E F;  3WCD A;  1JFG A;  4K10 A;  4L2X F;  1ZW5 A;  1EZF A;  2F7M F;  3M01 A;  3IPI A;  4P0X A;  1N1Z A;  3AE0 A;  5B01 A;  2FOR A;  5DHI A;  4EA2 A;  3N0F A;  3KRF A;  3ZMB A;  1N23 A;  3LSN A;  1YHM A;  2P1C A;  1KIZ A;  4Q23 A;  3VJE A;  3SDT A;  5IMI A;  4KQ5 A;  4OKZ A;  4P0V A;  4JXN A;  3TS7 A;  3Q2Z A;  3NRI A;  2E92 A;  3P41 A;  4F6X A;  3VJ8 A;  4FP4 A;  3MZV A;  5AYP A;  2E91 A;  2ZCS A;  4QPF A;  3APZ A;  3ICK A;  3EZ3 A;  3V66 A;  3ICM A;  4N1Z F;  3PYB A;  3WCI A;  4LTZ A;  4LOB A;  5HN9 A;  3ADZ A;  3VJD A;  3WE9 A;  4N9U A;  2ZCR A;  1WY0 A;  3B7L A;  2AZK A;  3EFQ A;  2E93 A;  1RTR A;  3LDW A;  3SDR A;  2F94 F;  2Z4X A;  3WCA A;  2Q9Y A;  5HN7 A;  4LZ0 A;  1KIY A;  2E8U A;  3M00 A;  4UMJ A;  4DZW A;  3KRA B;  3KRP A;  2QIS A;  2E8T A;  5E8H A;  5B0M A;  1UBX A;  2O1O A;  5EAU A;  4LUU A;  3SDV A;  3IBA A;  1DI1 A;  4LZ3 A;  2AET A;  3WCL A;  4GA3 A;  3PH7 A;  1VG7 A;  4LTV A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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