3ICNA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
molecule tags Transferase
source organism Trypanosoma cruzi
molecule keywords Farnesyl pyrophosphate synthase
total genus 148
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icnA00
4H5EF 1YV5A 5AYPA 5B02A 1JFGA 2QISA 4NFKF 2I19A 4K10A 3LGKA 1UBVA 1YHKA 5IK0A 3KB9A 1HX9A 4N1ZF 2E8XA 2Z52A 4KQ5A 2PS7A 4ZQ8A 3OYRA 4KVIA 5ILZA 3CP6A 3VJBA 2OPMA 5ILHA 3RYEA 4GP2A 3KRAA 4KUXA 2Z7HA 3CC9A 5AFXA 3Q2ZA 3WCEA 4PVXF 4DHDA 1V4IA 5ILJA 3WEKA 3QQVA 4KFAA 1N24A 2O1OA 4JYXA 4DWBA 4MC8A 5IM1A 1N22A 2ONGA 4GA3A 2F8CF 3NPKA 3M01A 1VG3A 3VJCA 5A0KA 3WEGA 2E92A 4KVDA 4KPJA 5DZ2A 4LPHF 3LGZB 4EA2A 4DZWA 1WL3A 3AQBB 3P5RA 1YYUA 4LOBA 2OA6A 3IBAA 3KROA 3AQ0A 4NFJF 3KRAB 4LFEA 3N49F 2VF6A 1EZFA 5DGNF 3TFPA 2F94F 5DJVF 4NG6A 4OKMA 4L2XF 4WK5A 3WCDA 3RMGA 5DJPF 4LXWA 3Q30A 3OABA 3WC9A 4LUUA 3W7FA 3N5JF 2Q58A 2Z4YA 3ASXA 3KRCA 3LLWA 2AELA 2Z50A 2ZY1A 4H5DF 5IMNA 4KQUA 3VJAA 2AZLA 4DXJA 3WEHA 3LMDA 3PKOA 2Q9ZA 1VG4A 4PVYF 5B0JA 1JFAA 2ZCRA 4RNQA 3KROB 5KSXF 3ICMA 1WL2A 5IMPA 3WCGA 3WCLA 1HXGA 4LLTA 3S4JA 3N0GA 4E1EA 2ZEVA 3VJDA 4LA6A 3S9VA 1KIYA 3VJ8A 5B03A 4DI5A 3ACXA 5DHIA 4RYPA 2E4OA 4LLSA 5B0KA 3OABB 3WEIA 3MZVA 5IL3A 5IK6A 5ILIA 5HN7A 3KRCB 5DIQF 2E8UA 2AEKA 3WCJA 3ZOUA 2PS5A 3IPIA 3WEJA 3WJOA 5JV1F 3G4DA 1YYSA 4LTVA 5DW7A 2E95A 4EA1A 3DYHA 3DYGA 3TFNA 2E8VA 3P8LA 3NRIA 3LVSA 3V1VA 3SDVA 3M00A 4NKEA 1V4HA 3WE9A 4P0XA 3TFVA 1YJ4A 1HXAA 3PH7A 3P8RA 5H9DA 3OACA 3N3LF 3RBMA 3N45F 3N1VF 3P41A 1HM7A 2OPNA 4P0WA 4MC3A 3M0GA 3V1XA 5HN9A 1ZW5A 1UBXA 3WCBA 2FTZA 3VJEA 3N3DA 2E93A 4XQSF 4KVYA 2AZKA 2J1PA 1HXCA 4OGUA 3PYBA 4OMGA 5HN8A 2ONHA 3LSNA 1UBYA 2F7MF 3WCMA 5DGSF 5IKAA 3SDUA 2Z4VA 5IK9A 4F6XA 4OMHA 3AQCB 4DWGA 4RXAA 2F89F 4LFGA 5AHUB 5EAUA 1N1ZA 1WL1A 3ICKA 5CG5A 2ZCSA 3OACB 1DI1A 2PS4A 5IMIA 5E8LA 4NFIF 3WEFA 3N1WF 3KRPA 3ZL6A 2DH4A 3UCAA 3WSAA 4H5CF 5EROA 5EASA 3LK5A 5E8HA 5B01A 3G4FA 2RAHA 5AELA 5ILDA 3KRFA 3WCCA 5IVGA 3ZCDA 5IL8A 4LFVF 1V4JA 1KIZA 3TS7A 1FPSA 1WKZA 1PS1A 1YHLA 5ILKA 3BNXA 1VG6A 5ILYA 4XQTF 4LTZA 3PYAA 2ZCQA 4QPFA 4UMJA 1N20A 3SAEA 2FORA 5ER8A 4Q23A 3APZA 3LDWA 5E8KA 5ERMA 3AE0A 3KRPB 4FP4A 2P1CA 3CKEA 1UBWA 4RXDA 3LJIA 3LG5A 2AETA 5DJRF 3MAVA 2Q9YA 4NKFA 5A0JA 3WJKA 3ID0A 2E94A 4KKMA 3KRFB 4NUAA 4OKZA 1WL0A 5HNAA 2AZJA 4E9UA 2F92F 5IN8A 3N46F 4LPGF 3ZMBA 4GP1A 2Q80A 3WCIA 1YQ7A 1HM4A 4EA0A 3N5HF 5IKHA 4KK2A 3PDEA 2Z4WA 3QKCA 2F9KF 3WCHA 1WMWA 5C05A 5JUZF 3WCFA 3NF2A 3ZMCA 1RTRA 3ICZA 4E9ZA 3N6KF 3SDTA 4JXNA 3BNYA 4KWDA 3VJ9A 4LZ0A 2ZCOA 1RQJA 3ICNA 1YYQA 1VG7A 3EFQA 3ACWA 3N0FA 4XQRF 5JA0F 4RXEA 5I1UA 3WCAA 4KPDA 1DGPA 4RXCA 1RQIA 2Z4ZA 3NPRA 4N9UA 4FJQA 2F8ZF 3ACYA 2PS6A 3LZ9A 5A0IA 3Q2QA 3V66A 3B7LA 3SDRA 2H8OA 4KQSA 1V4EA 1VG2A 3Q1OA 4JZXA 2Z7IA 5JV0F 1YHMA 5B0MA 2PS8A 2OGDA 1YYRA 4LIXA 3EZ3A 5B0IA 3ADZA 4GAXA 5CG6A 2E8TA 3DYFA 3SDQA 2Z78A 1N23A 2E91A 2E90A 4MC0A 4F6VA 2Z4XA 5DHKA 5B0LA 5B00A 4DEMF 3RYWA 1WY0A 1YYTA 4F62A 1V4KA 5JV2F 3WJNA 4LZ3A 4P0VA 3TC1A 5ERNA 4HD1A 3P5PA 2EWGA 1N21A 4JXYA 4QXSF 3KBKA 1N1BA 4JVJF 4LA5A 4KVWA 3LOMA 3LEEA 3WSBA 3M02A 4LZCA 4JZBA 5DGMF 2J5CA 2J1OA 2ZEUA 3EGTA 3M9UA 5EATA 2E8WA
chains in the Genus database with same CATH superfamily
4H5EF 1YV5A 5AYPA 5B02A 1JFGA 2QISA 4NFKF 2I19A 4K10A 3LGKA 1UBVA 1YHKA 5IK0A 3KB9A 1HX9A 4N1ZF 2E8XA 2Z52A 4KQ5A 2PS7A 4ZQ8A 3OYRA 4KVIA 5ILZA 3CP6A 3VJBA 2OPMA 5ILHA 3RYEA 4GP2A 3KRAA 4KUXA 2Z7HA 3CC9A 5AFXA 3Q2ZA 3WCEA 4PVXF 4DHDA 1V4IA 5ILJA 3WEKA 3QQVA 4KFAA 1N24A 2O1OA 4JYXA 4DWBA 4MC8A 5IM1A 1N22A 2ONGA 4GA3A 2F8CF 3NPKA 3M01A 1VG3A 3VJCA 5A0KA 3WEGA 2E92A 4KVDA 4KPJA 5DZ2A 4LPHF 3LGZB 4EA2A 4DZWA 1WL3A 3AQBB 3P5RA 1YYUA 4LOBA 2OA6A 3IBAA 3KROA 3AQ0A 4NFJF 3KRAB 4LFEA 3N49F 2VF6A 1EZFA 5DGNF 3TFPA 2F94F 5DJVF 4NG6A 4OKMA 4L2XF 4WK5A 3WCDA 3RMGA 5DJPF 4LXWA 3Q30A 3OABA 3WC9A 4LUUA 3W7FA 3N5JF 2Q58A 2Z4YA 3ASXA 3KRCA 3LLWA 2AELA 2Z50A 2ZY1A 4H5DF 5IMNA 4KQUA 3VJAA 2AZLA 4DXJA 3WEHA 3LMDA 3PKOA 2Q9ZA 1VG4A 4PVYF 5B0JA 1JFAA 2ZCRA 4RNQA 3KROB 5KSXF 3ICMA 1WL2A 5IMPA 3WCGA 3WCLA 1HXGA 4LLTA 3S4JA 3N0GA 4E1EA 2ZEVA 3VJDA 4LA6A 3S9VA 1KIYA 3VJ8A 5B03A 4DI5A 3ACXA 5DHIA 4RYPA 2E4OA 4LLSA 5B0KA 3OABB 3WEIA 3MZVA 5IL3A 5IK6A 5ILIA 5HN7A 3KRCB 5DIQF 2E8UA 2AEKA 3WCJA 3ZOUA 2PS5A 3IPIA 3WEJA 3WJOA 5JV1F 3G4DA 1YYSA 4LTVA 5DW7A 2E95A 4EA1A 3DYHA 3DYGA 3TFNA 2E8VA 3P8LA 3NRIA 3LVSA 3V1VA 3SDVA 3M00A 4NKEA 1V4HA 3WE9A 4P0XA 3TFVA 1YJ4A 1HXAA 3PH7A 3P8RA 5H9DA 3OACA 3N3LF 3RBMA 3N45F 3N1VF 3P41A 1HM7A 2OPNA 4P0WA 4MC3A 3M0GA 3V1XA 5HN9A 1ZW5A 1UBXA 3WCBA 2FTZA 3VJEA 3N3DA 2E93A 4XQSF 4KVYA 2AZKA 2J1PA 1HXCA 4OGUA 3PYBA 4OMGA 5HN8A 2ONHA 3LSNA 1UBYA 2F7MF 3WCMA 5DGSF 5IKAA 3SDUA 2Z4VA 5IK9A 4F6XA 4OMHA 3AQCB 4DWGA 4RXAA 2F89F 4LFGA 5AHUB 5EAUA 1N1ZA 1WL1A 3ICKA 5CG5A 2ZCSA 3OACB 1DI1A 2PS4A 5IMIA 5E8LA 4NFIF 3WEFA 3N1WF 3KRPA 3ZL6A 2DH4A 3UCAA 3WSAA 4H5CF 5EROA 5EASA 3LK5A 5E8HA 5B01A 3G4FA 2RAHA 5AELA 5ILDA 3KRFA 3WCCA 5IVGA 3ZCDA 5IL8A 4LFVF 1V4JA 1KIZA 3TS7A 1FPSA 1WKZA 1PS1A 1YHLA 5ILKA 3BNXA 1VG6A 5ILYA 4XQTF 4LTZA 3PYAA 2ZCQA 4QPFA 4UMJA 1N20A 3SAEA 2FORA 5ER8A 4Q23A 3APZA 3LDWA 5E8KA 5ERMA 3AE0A 3KRPB 4FP4A 2P1CA 3CKEA 1UBWA 4RXDA 3LJIA 3LG5A 2AETA 5DJRF 3MAVA 2Q9YA 4NKFA 5A0JA 3WJKA 3ID0A 2E94A 4KKMA 3KRFB 4NUAA 4OKZA 1WL0A 5HNAA 2AZJA 4E9UA 2F92F 5IN8A 3N46F 4LPGF 3ZMBA 4GP1A 2Q80A 3WCIA 1YQ7A 1HM4A 4EA0A 3N5HF 5IKHA 4KK2A 3PDEA 2Z4WA 3QKCA 2F9KF 3WCHA 1WMWA 5C05A 5JUZF 3WCFA 3NF2A 3ZMCA 1RTRA 3ICZA 4E9ZA 3N6KF 3SDTA 4JXNA 3BNYA 4KWDA 3VJ9A 4LZ0A 2ZCOA 1RQJA 3ICNA 1YYQA 1VG7A 3EFQA 3ACWA 3N0FA 4XQRF 5JA0F 4RXEA 5I1UA 3WCAA 4KPDA 1DGPA 4RXCA 1RQIA 2Z4ZA 3NPRA 4N9UA 4FJQA 2F8ZF 3ACYA 2PS6A 3LZ9A 5A0IA 3Q2QA 3V66A 3B7LA 3SDRA 2H8OA 4KQSA 1V4EA 1VG2A 3Q1OA 4JZXA 2Z7IA 5JV0F 1YHMA 5B0MA 2PS8A 2OGDA 1YYRA 4LIXA 3EZ3A 5B0IA 3ADZA 4GAXA 5CG6A 2E8TA 3DYFA 3SDQA 2Z78A 1N23A 2E91A 2E90A 4MC0A 4F6VA 2Z4XA 5DHKA 5B0LA 5B00A 4DEMF 3RYWA 1WY0A 1YYTA 4F62A 1V4KA 5JV2F 3WJNA 4LZ3A 4P0VA 3TC1A 5ERNA 4HD1A 3P5PA 2EWGA 1N21A 4JXYA 4QXSF 3KBKA 1N1BA 4JVJF 4LA5A 4KVWA 3LOMA 3LEEA 3WSBA 3M02A 4LZCA 4JZBA 5DGMF 2J5CA 2J1OA 2ZEUA 3EGTA 3M9UA 5EATA 2E8WA
chains in the Genus database with same CATH topology
4H5EF 1YV5A 5AYPA 5B02A 1JFGA 2QISA 4NFKF 2I19A 4K10A 3LGKA 1UBVA 1YHKA 5IK0A 3KB9A 1HX9A 4N1ZF 2E8XA 2Z52A 4KQ5A 2PS7A 4ZQ8A 3OYRA 4KVIA 5ILZA 3CP6A 3VJBA 2OPMA 5ILHA 3RYEA 4GP2A 3KRAA 4KUXA 2Z7HA 3CC9A 5AFXA 3Q2ZA 3WCEA 4PVXF 4DHDA 1V4IA 5ILJA 3WEKA 3QQVA 4KFAA 1N24A 2O1OA 4JYXA 4DWBA 4MC8A 5IM1A 1N22A 2ONGA 4GA3A 2F8CF 3NPKA 3M01A 1VG3A 3VJCA 5A0KA 3WEGA 2E92A 4KVDA 4KPJA 5DZ2A 4LPHF 3LGZB 4EA2A 4DZWA 1WL3A 3AQBB 3P5RA 1YYUA 4LOBA 2OA6A 3IBAA 3KROA 3AQ0A 4NFJF 3KRAB 4LFEA 3N49F 2VF6A 1EZFA 5DGNF 3TFPA 2F94F 5DJVF 4NG6A 4OKMA 4L2XF 4WK5A 3WCDA 3RMGA 5DJPF 4LXWA 3Q30A 3OABA 3WC9A 4LUUA 3W7FA 3N5JF 2Q58A 2Z4YA 3ASXA 3KRCA 3LLWA 2AELA 2Z50A 2ZY1A 4H5DF 5IMNA 4KQUA 3VJAA 2AZLA 4DXJA 3WEHA 3LMDA 3PKOA 2Q9ZA 1VG4A 4PVYF 5B0JA 1JFAA 2ZCRA 4RNQA 3KROB 5KSXF 3ICMA 1WL2A 5IMPA 3WCGA 3WCLA 1HXGA 4LLTA 3S4JA 3N0GA 4E1EA 2ZEVA 3VJDA 4LA6A 3S9VA 1KIYA 3VJ8A 5B03A 4DI5A 3ACXA 5DHIA 4RYPA 2E4OA 4LLSA 5B0KA 3OABB 3WEIA 3MZVA 5IL3A 5IK6A 5ILIA 5HN7A 3KRCB 5DIQF 2E8UA 2AEKA 3WCJA 3ZOUA 2PS5A 3IPIA 3WEJA 3WJOA 5JV1F 3G4DA 1YYSA 4LTVA 5DW7A 2E95A 4EA1A 3DYHA 3DYGA 3TFNA 2E8VA 3P8LA 3NRIA 3LVSA 3V1VA 3SDVA 3M00A 4NKEA 1V4HA 3WE9A 4P0XA 3TFVA 1YJ4A 1HXAA 3PH7A 3P8RA 5H9DA 3OACA 3N3LF 3RBMA 3N45F 3N1VF 3P41A 1HM7A 2OPNA 4P0WA 4MC3A 3M0GA 3V1XA 5HN9A 1ZW5A 1UBXA 3WCBA 2FTZA 3VJEA 3N3DA 2E93A 4XQSF 4KVYA 2AZKA 2J1PA 1HXCA 4OGUA 3PYBA 4OMGA 5HN8A 2ONHA 3LSNA 1UBYA 2F7MF 3WCMA 5DGSF 5IKAA 3SDUA 2Z4VA 5IK9A 4F6XA 4OMHA 3AQCB 4DWGA 4RXAA 2F89F 4LFGA 5AHUB 5EAUA 1N1ZA 1WL1A 3ICKA 5CG5A 2ZCSA 3OACB 1DI1A 2PS4A 5IMIA 5E8LA 4NFIF 3WEFA 3N1WF 3KRPA 3ZL6A 2DH4A 3UCAA 3WSAA 4H5CF 5EROA 5EASA 3LK5A 5E8HA 5B01A 3G4FA 2RAHA 5AELA 5ILDA 3KRFA 3WCCA 5IVGA 3ZCDA 5IL8A 4LFVF 1V4JA 1KIZA 3TS7A 1FPSA 1WKZA 1PS1A 1YHLA 5ILKA 3BNXA 1VG6A 5ILYA 4XQTF 4LTZA 3PYAA 2ZCQA 4QPFA 4UMJA 1N20A 3SAEA 2FORA 5ER8A 4Q23A 3APZA 3LDWA 5E8KA 5ERMA 3AE0A 3KRPB 4FP4A 2P1CA 3CKEA 1UBWA 4RXDA 3LJIA 3LG5A 2AETA 5DJRF 3MAVA 2Q9YA 4NKFA 5A0JA 3WJKA 3ID0A 2E94A 4KKMA 3KRFB 4NUAA 4OKZA 1WL0A 5HNAA 2AZJA 4E9UA 2F92F 5IN8A 3N46F 4LPGF 3ZMBA 4GP1A 2Q80A 3WCIA 1YQ7A 1HM4A 4EA0A 3N5HF 5IKHA 4KK2A 3PDEA 2Z4WA 3QKCA 2F9KF 3WCHA 1WMWA 5C05A 5JUZF 3WCFA 3NF2A 3ZMCA 1RTRA 3ICZA 4E9ZA 3N6KF 3SDTA 4JXNA 3BNYA 4KWDA 3VJ9A 4LZ0A 2ZCOA 1RQJA 3ICNA 1YYQA 1VG7A 3EFQA 3ACWA 3N0FA 4XQRF 5JA0F 4RXEA 5I1UA 3WCAA 4KPDA 1DGPA 4RXCA 1RQIA 2Z4ZA 3NPRA 4N9UA 4FJQA 2F8ZF 3ACYA 2PS6A 3LZ9A 5A0IA 3Q2QA 3V66A 3B7LA 3SDRA 2H8OA 4KQSA 1V4EA 1VG2A 3Q1OA 4JZXA 2Z7IA 5JV0F 1YHMA 5B0MA 2PS8A 2OGDA 1YYRA 4LIXA 3EZ3A 5B0IA 3ADZA 4GAXA 5CG6A 2E8TA 3DYFA 3SDQA 2Z78A 1N23A 2E91A 2E90A 4MC0A 4F6VA 2Z4XA 5DHKA 5B0LA 5B00A 4DEMF 3RYWA 1WY0A 1YYTA 4F62A 1V4KA 5JV2F 3WJNA 4LZ3A 4P0VA 3TC1A 5ERNA 4HD1A 3P5PA 2EWGA 1N21A 4JXYA 4QXSF 3KBKA 1N1BA 4JVJF 4LA5A 4KVWA 3LOMA 3LEEA 3WSBA 3M02A 4LZCA 4JZBA 5DGMF 2J5CA 2J1OA 2ZEUA 3EGTA 3M9UA 5EATA 2E8WA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4H5E F;  1YV5 A;  5AYP A;  5B02 A;  1JFG A;  2QIS A;  4NFK F;  2I19 A;  4K10 A;  3LGK A;  1UBV A;  1YHK A;  5IK0 A;  3KB9 A;  1HX9 A;  4N1Z F;  2E8X A;  2Z52 A;  4KQ5 A;  2PS7 A;  4ZQ8 A;  3OYR A;  4KVI A;  5ILZ A;  3CP6 A;  3VJB A;  2OPM A;  5ILH A;  3RYE A;  4GP2 A;  3KRA A;  4KUX A;  2Z7H A;  3CC9 A;  5AFX A;  3Q2Z A;  3WCE A;  4PVX F;  4DHD A;  1V4I A;  5ILJ A;  3WEK A;  3QQV A;  4KFA A;  1N24 A;  2O1O A;  4JYX A;  4DWB A;  4MC8 A;  5IM1 A;  1N22 A;  2ONG A;  4GA3 A;  2F8C F;  3NPK A;  3M01 A;  1VG3 A;  3VJC A;  5A0K A;  3WEG A;  2E92 A;  4KVD A;  4KPJ A;  5DZ2 A;  4LPH F;  3LGZ B;  4EA2 A;  4DZW A;  1WL3 A;  3AQB B;  3P5R A;  1YYU A;  4LOB A;  2OA6 A;  3IBA A;  3KRO A;  3AQ0 A;  4NFJ F;  3KRA B;  4LFE A;  3N49 F;  2VF6 A;  1EZF A;  5DGN F;  3TFP A;  2F94 F;  5DJV F;  4NG6 A;  4OKM A;  4L2X F;  4WK5 A;  3WCD A;  3RMG A;  5DJP F;  4LXW A;  3Q30 A;  3OAB A;  3WC9 A;  4LUU A;  3W7F A;  3N5J F;  2Q58 A;  2Z4Y A;  3ASX A;  3KRC A;  3LLW A;  2AEL A;  2Z50 A;  2ZY1 A;  4H5D F;  5IMN A;  4KQU A;  3VJA A;  2AZL A;  4DXJ A;  3WEH A;  3LMD A;  3PKO A;  2Q9Z A;  1VG4 A;  4PVY F;  5B0J A;  1JFA A;  2ZCR A;  4RNQ A;  3KRO B;  5KSX F;  3ICM A;  1WL2 A;  5IMP A;  3WCG A;  3WCL A;  1HXG A;  4LLT A;  3S4J A;  3N0G A;  4E1E A;  2ZEV A;  3VJD A;  4LA6 A;  3S9V A;  1KIY A;  3VJ8 A;  5B03 A;  4DI5 A;  3ACX A;  5DHI A;  4RYP A;  2E4O A;  4LLS A;  5B0K A;  3OAB B;  3WEI A;  3MZV A;  5IL3 A;  5IK6 A;  5ILI A;  5HN7 A;  3KRC B;  5DIQ F;  2E8U A;  2AEK A;  3WCJ A;  3ZOU A;  2PS5 A;  3IPI A;  3WEJ A;  3WJO A;  5JV1 F;  3G4D A;  1YYS A;  4LTV A;  5DW7 A;  2E95 A;  4EA1 A;  3DYH A;  3DYG A;  3TFN A;  2E8V A;  3P8L A;  3NRI A;  3LVS A;  3V1V A;  3SDV A;  3M00 A;  4NKE A;  1V4H A;  3WE9 A;  4P0X A;  3TFV A;  1YJ4 A;  1HXA A;  3PH7 A;  3P8R A;  5H9D A;  3OAC A;  3N3L F;  3RBM A;  3N45 F;  3N1V F;  3P41 A;  1HM7 A;  2OPN A;  4P0W A;  4MC3 A;  3M0G A;  3V1X A;  5HN9 A;  1ZW5 A;  1UBX A;  3WCB A;  2FTZ A;  3VJE A;  3N3D A;  2E93 A;  4XQS F;  4KVY A;  2AZK A;  2J1P A;  1HXC A;  4OGU A;  3PYB A;  4OMG A;  5HN8 A;  2ONH A;  3LSN A;  1UBY A;  2F7M F;  3WCM A;  5DGS F;  5IKA A;  3SDU A;  2Z4V A;  5IK9 A;  4F6X A;  4OMH A;  3AQC B;  4DWG A;  4RXA A;  2F89 F;  4LFG A;  5AHU B;  5EAU A;  1N1Z A;  1WL1 A;  3ICK A;  5CG5 A;  2ZCS A;  3OAC B;  1DI1 A;  2PS4 A;  5IMI A;  5E8L A;  4NFI F;  3WEF A;  3N1W F;  3KRP A;  3ZL6 A;  2DH4 A;  3UCA A;  3WSA A;  4H5C F;  5ERO A;  5EAS A;  3LK5 A;  5E8H A;  5B01 A;  3G4F A;  2RAH A;  5AEL A;  5ILD A;  3KRF A;  3WCC A;  5IVG A;  3ZCD A;  5IL8 A;  4LFV F;  1V4J A;  1KIZ A;  3TS7 A;  1FPS A;  1WKZ A;  1PS1 A;  1YHL A;  5ILK A;  3BNX A;  1VG6 A;  5ILY A;  4XQT F;  4LTZ A;  3PYA A;  2ZCQ A;  4QPF A;  4UMJ A;  1N20 A;  3SAE A;  2FOR A;  5ER8 A;  4Q23 A;  3APZ A;  3LDW A;  5E8K A;  5ERM A;  3AE0 A;  3KRP B;  4FP4 A;  2P1C A;  3CKE A;  1UBW A;  4RXD A;  3LJI A;  3LG5 A;  2AET A;  5DJR F;  3MAV A;  2Q9Y A;  4NKF A;  5A0J A;  3WJK A;  3ID0 A;  2E94 A;  4KKM A;  3KRF B;  4NUA A;  4OKZ A;  1WL0 A;  5HNA A;  2AZJ A;  4E9U A;  2F92 F;  5IN8 A;  3N46 F;  4LPG F;  3ZMB A;  4GP1 A;  2Q80 A;  3WCI A;  1YQ7 A;  1HM4 A;  4EA0 A;  3N5H F;  5IKH A;  4KK2 A;  3PDE A;  2Z4W A;  3QKC A;  2F9K F;  3WCH A;  1WMW A;  5C05 A;  5JUZ F;  3WCF A;  3NF2 A;  3ZMC A;  1RTR A;  3ICZ A;  4E9Z A;  3N6K F;  3SDT A;  4JXN A;  3BNY A;  4KWD A;  3VJ9 A;  4LZ0 A;  2ZCO A;  1RQJ A;  3ICN A;  1YYQ A;  1VG7 A;  3EFQ A;  3ACW A;  3N0F A;  4XQR F;  5JA0 F;  4RXE A;  5I1U A;  3WCA A;  4KPD A;  1DGP A;  4RXC A;  1RQI A;  2Z4Z A;  3NPR A;  4N9U A;  4FJQ A;  2F8Z F;  3ACY A;  2PS6 A;  3LZ9 A;  5A0I A;  3Q2Q A;  3V66 A;  3B7L A;  3SDR A;  2H8O A;  4KQS A;  1V4E A;  1VG2 A;  3Q1O A;  4JZX A;  2Z7I A;  5JV0 F;  1YHM A;  5B0M A;  2PS8 A;  2OGD A;  1YYR A;  4LIX A;  3EZ3 A;  5B0I A;  3ADZ A;  4GAX A;  5CG6 A;  2E8T A;  3DYF A;  3SDQ A;  2Z78 A;  1N23 A;  2E91 A;  2E90 A;  4MC0 A;  4F6V A;  2Z4X A;  5DHK A;  5B0L A;  5B00 A;  4DEM F;  3RYW A;  1WY0 A;  1YYT A;  4F62 A;  1V4K A;  5JV2 F;  3WJN A;  4LZ3 A;  4P0V A;  3TC1 A;  5ERN A;  4HD1 A;  3P5P A;  2EWG A;  1N21 A;  4JXY A;  4QXS F;  3KBK A;  1N1B A;  4JVJ F;  4LA5 A;  4KVW A;  3LOM A;  3LEE A;  3WSB A;  3M02 A;  4LZC A;  4JZB A;  5DGM F;  2J5C A;  2J1O A;  2ZEU A;  3EGT A;  3M9U A;  5EAT A;  2E8W A; 
#chains in the Genus database with same CATH topology
 4H5E F;  1YV5 A;  5AYP A;  5B02 A;  1JFG A;  2QIS A;  4NFK F;  2I19 A;  4K10 A;  3LGK A;  1UBV A;  1YHK A;  5IK0 A;  3KB9 A;  1HX9 A;  4N1Z F;  2E8X A;  2Z52 A;  4KQ5 A;  2PS7 A;  4ZQ8 A;  3OYR A;  4KVI A;  5ILZ A;  3CP6 A;  3VJB A;  2OPM A;  5ILH A;  3RYE A;  4GP2 A;  3KRA A;  4KUX A;  2Z7H A;  3CC9 A;  5AFX A;  3Q2Z A;  3WCE A;  4PVX F;  4DHD A;  1V4I A;  5ILJ A;  3WEK A;  3QQV A;  4KFA A;  1N24 A;  2O1O A;  4JYX A;  4DWB A;  4MC8 A;  5IM1 A;  1N22 A;  2ONG A;  4GA3 A;  2F8C F;  3NPK A;  3M01 A;  1VG3 A;  3VJC A;  5A0K A;  3WEG A;  2E92 A;  4KVD A;  4KPJ A;  5DZ2 A;  4LPH F;  3LGZ B;  4EA2 A;  4DZW A;  1WL3 A;  3AQB B;  3P5R A;  1YYU A;  4LOB A;  2OA6 A;  3IBA A;  3KRO A;  3AQ0 A;  4NFJ F;  3KRA B;  4LFE A;  3N49 F;  2VF6 A;  1EZF A;  5DGN F;  3TFP A;  2F94 F;  5DJV F;  4NG6 A;  4OKM A;  4L2X F;  4WK5 A;  3WCD A;  3RMG A;  5DJP F;  4LXW A;  3Q30 A;  3OAB A;  3WC9 A;  4LUU A;  3W7F A;  3N5J F;  2Q58 A;  2Z4Y A;  3ASX A;  3KRC A;  3LLW A;  2AEL A;  2Z50 A;  2ZY1 A;  4H5D F;  5IMN A;  4KQU A;  3VJA A;  2AZL A;  4DXJ A;  3WEH A;  3LMD A;  3PKO A;  2Q9Z A;  1VG4 A;  4PVY F;  5B0J A;  1JFA A;  2ZCR A;  4RNQ A;  3KRO B;  5KSX F;  3ICM A;  1WL2 A;  5IMP A;  3WCG A;  3WCL A;  1HXG A;  4LLT A;  3S4J A;  3N0G A;  4E1E A;  2ZEV A;  3VJD A;  4LA6 A;  3S9V A;  1KIY A;  3VJ8 A;  5B03 A;  4DI5 A;  3ACX A;  5DHI A;  4RYP A;  2E4O A;  4LLS A;  5B0K A;  3OAB B;  3WEI A;  3MZV A;  5IL3 A;  5IK6 A;  5ILI A;  5HN7 A;  3KRC B;  5DIQ F;  2E8U A;  2AEK A;  3WCJ A;  3ZOU A;  2PS5 A;  3IPI A;  3WEJ A;  3WJO A;  5JV1 F;  3G4D A;  1YYS A;  4LTV A;  5DW7 A;  2E95 A;  4EA1 A;  3DYH A;  3DYG A;  3TFN A;  2E8V A;  3P8L A;  3NRI A;  3LVS A;  3V1V A;  3SDV A;  3M00 A;  4NKE A;  1V4H A;  3WE9 A;  4P0X A;  3TFV A;  1YJ4 A;  1HXA A;  3PH7 A;  3P8R A;  5H9D A;  3OAC A;  3N3L F;  3RBM A;  3N45 F;  3N1V F;  3P41 A;  1HM7 A;  2OPN A;  4P0W A;  4MC3 A;  3M0G A;  3V1X A;  5HN9 A;  1ZW5 A;  1UBX A;  3WCB A;  2FTZ A;  3VJE A;  3N3D A;  2E93 A;  4XQS F;  4KVY A;  2AZK A;  2J1P A;  1HXC A;  4OGU A;  3PYB A;  4OMG A;  5HN8 A;  2ONH A;  3LSN A;  1UBY A;  2F7M F;  3WCM A;  5DGS F;  5IKA A;  3SDU A;  2Z4V A;  5IK9 A;  4F6X A;  4OMH A;  3AQC B;  4DWG A;  4RXA A;  2F89 F;  4LFG A;  5AHU B;  5EAU A;  1N1Z A;  1WL1 A;  3ICK A;  5CG5 A;  2ZCS A;  3OAC B;  1DI1 A;  2PS4 A;  5IMI A;  5E8L A;  4NFI F;  3WEF A;  3N1W F;  3KRP A;  3ZL6 A;  2DH4 A;  3UCA A;  3WSA A;  4H5C F;  5ERO A;  5EAS A;  3LK5 A;  5E8H A;  5B01 A;  3G4F A;  2RAH A;  5AEL A;  5ILD A;  3KRF A;  3WCC A;  5IVG A;  3ZCD A;  5IL8 A;  4LFV F;  1V4J A;  1KIZ A;  3TS7 A;  1FPS A;  1WKZ A;  1PS1 A;  1YHL A;  5ILK A;  3BNX A;  1VG6 A;  5ILY A;  4XQT F;  4LTZ A;  3PYA A;  2ZCQ A;  4QPF A;  4UMJ A;  1N20 A;  3SAE A;  2FOR A;  5ER8 A;  4Q23 A;  3APZ A;  3LDW A;  5E8K A;  5ERM A;  3AE0 A;  3KRP B;  4FP4 A;  2P1C A;  3CKE A;  1UBW A;  4RXD A;  3LJI A;  3LG5 A;  2AET A;  5DJR F;  3MAV A;  2Q9Y A;  4NKF A;  5A0J A;  3WJK A;  3ID0 A;  2E94 A;  4KKM A;  3KRF B;  4NUA A;  4OKZ A;  1WL0 A;  5HNA A;  2AZJ A;  4E9U A;  2F92 F;  5IN8 A;  3N46 F;  4LPG F;  3ZMB A;  4GP1 A;  2Q80 A;  3WCI A;  1YQ7 A;  1HM4 A;  4EA0 A;  3N5H F;  5IKH A;  4KK2 A;  3PDE A;  2Z4W A;  3QKC A;  2F9K F;  3WCH A;  1WMW A;  5C05 A;  5JUZ F;  3WCF A;  3NF2 A;  3ZMC A;  1RTR A;  3ICZ A;  4E9Z A;  3N6K F;  3SDT A;  4JXN A;  3BNY A;  4KWD A;  3VJ9 A;  4LZ0 A;  2ZCO A;  1RQJ A;  3ICN A;  1YYQ A;  1VG7 A;  3EFQ A;  3ACW A;  3N0F A;  4XQR F;  5JA0 F;  4RXE A;  5I1U A;  3WCA A;  4KPD A;  1DGP A;  4RXC A;  1RQI A;  2Z4Z A;  3NPR A;  4N9U A;  4FJQ A;  2F8Z F;  3ACY A;  2PS6 A;  3LZ9 A;  5A0I A;  3Q2Q A;  3V66 A;  3B7L A;  3SDR A;  2H8O A;  4KQS A;  1V4E A;  1VG2 A;  3Q1O A;  4JZX A;  2Z7I A;  5JV0 F;  1YHM A;  5B0M A;  2PS8 A;  2OGD A;  1YYR A;  4LIX A;  3EZ3 A;  5B0I A;  3ADZ A;  4GAX A;  5CG6 A;  2E8T A;  3DYF A;  3SDQ A;  2Z78 A;  1N23 A;  2E91 A;  2E90 A;  4MC0 A;  4F6V A;  2Z4X A;  5DHK A;  5B0L A;  5B00 A;  4DEM F;  3RYW A;  1WY0 A;  1YYT A;  4F62 A;  1V4K A;  5JV2 F;  3WJN A;  4LZ3 A;  4P0V A;  3TC1 A;  5ERN A;  4HD1 A;  3P5P A;  2EWG A;  1N21 A;  4JXY A;  4QXS F;  3KBK A;  1N1B A;  4JVJ F;  4LA5 A;  4KVW A;  3LOM A;  3LEE A;  3WSB A;  3M02 A;  4LZC A;  4JZB A;  5DGM F;  2J5C A;  2J1O A;  2ZEU A;  3EGT A;  3M9U A;  5EAT A;  2E8W A; 
#chains in the Genus database with same CATH homology
 4H5E F;  1YV5 A;  5AYP A;  5B02 A;  1JFG A;  2QIS A;  4NFK F;  2I19 A;  4K10 A;  3LGK A;  1UBV A;  1YHK A;  5IK0 A;  3KB9 A;  1HX9 A;  4N1Z F;  2E8X A;  2Z52 A;  4KQ5 A;  2PS7 A;  4ZQ8 A;  3OYR A;  4KVI A;  5ILZ A;  3CP6 A;  3VJB A;  2OPM A;  5ILH A;  3RYE A;  4GP2 A;  3KRA A;  4KUX A;  2Z7H A;  3CC9 A;  5AFX A;  3Q2Z A;  3WCE A;  4PVX F;  4DHD A;  1V4I A;  5ILJ A;  3WEK A;  3QQV A;  4KFA A;  1N24 A;  2O1O A;  4JYX A;  4DWB A;  4MC8 A;  5IM1 A;  1N22 A;  2ONG A;  4GA3 A;  2F8C F;  3NPK A;  3M01 A;  1VG3 A;  3VJC A;  5A0K A;  3WEG A;  2E92 A;  4KVD A;  4KPJ A;  5DZ2 A;  4LPH F;  3LGZ B;  4EA2 A;  4DZW A;  1WL3 A;  3AQB B;  3P5R A;  1YYU A;  4LOB A;  2OA6 A;  3IBA A;  3KRO A;  3AQ0 A;  4NFJ F;  3KRA B;  4LFE A;  3N49 F;  2VF6 A;  1EZF A;  5DGN F;  3TFP A;  2F94 F;  5DJV F;  4NG6 A;  4OKM A;  4L2X F;  4WK5 A;  3WCD A;  3RMG A;  5DJP F;  4LXW A;  3Q30 A;  3OAB A;  3WC9 A;  4LUU A;  3W7F A;  3N5J F;  2Q58 A;  2Z4Y A;  3ASX A;  3KRC A;  3LLW A;  2AEL A;  2Z50 A;  2ZY1 A;  4H5D F;  5IMN A;  4KQU A;  3VJA A;  2AZL A;  4DXJ A;  3WEH A;  3LMD A;  3PKO A;  2Q9Z A;  1VG4 A;  4PVY F;  5B0J A;  1JFA A;  2ZCR A;  4RNQ A;  3KRO B;  5KSX F;  3ICM A;  1WL2 A;  5IMP A;  3WCG A;  3WCL A;  1HXG A;  4LLT A;  3S4J A;  3N0G A;  4E1E A;  2ZEV A;  3VJD A;  4LA6 A;  3S9V A;  1KIY A;  3VJ8 A;  5B03 A;  4DI5 A;  3ACX A;  5DHI A;  4RYP A;  2E4O A;  4LLS A;  5B0K A;  3OAB B;  3WEI A;  3MZV A;  5IL3 A;  5IK6 A;  5ILI A;  5HN7 A;  3KRC B;  5DIQ F;  2E8U A;  2AEK A;  3WCJ A;  3ZOU A;  2PS5 A;  3IPI A;  3WEJ A;  3WJO A;  5JV1 F;  3G4D A;  1YYS A;  4LTV A;  5DW7 A;  2E95 A;  4EA1 A;  3DYH A;  3DYG A;  3TFN A;  2E8V A;  3P8L A;  3NRI A;  3LVS A;  3V1V A;  3SDV A;  3M00 A;  4NKE A;  1V4H A;  3WE9 A;  4P0X A;  3TFV A;  1YJ4 A;  1HXA A;  3PH7 A;  3P8R A;  5H9D A;  3OAC A;  3N3L F;  3RBM A;  3N45 F;  3N1V F;  3P41 A;  1HM7 A;  2OPN A;  4P0W A;  4MC3 A;  3M0G A;  3V1X A;  5HN9 A;  1ZW5 A;  1UBX A;  3WCB A;  2FTZ A;  3VJE A;  3N3D A;  2E93 A;  4XQS F;  4KVY A;  2AZK A;  2J1P A;  1HXC A;  4OGU A;  3PYB A;  4OMG A;  5HN8 A;  2ONH A;  3LSN A;  1UBY A;  2F7M F;  3WCM A;  5DGS F;  5IKA A;  3SDU A;  2Z4V A;  5IK9 A;  4F6X A;  4OMH A;  3AQC B;  4DWG A;  4RXA A;  2F89 F;  4LFG A;  5AHU B;  5EAU A;  1N1Z A;  1WL1 A;  3ICK A;  5CG5 A;  2ZCS A;  3OAC B;  1DI1 A;  2PS4 A;  5IMI A;  5E8L A;  4NFI F;  3WEF A;  3N1W F;  3KRP A;  3ZL6 A;  2DH4 A;  3UCA A;  3WSA A;  4H5C F;  5ERO A;  5EAS A;  3LK5 A;  5E8H A;  5B01 A;  3G4F A;  2RAH A;  5AEL A;  5ILD A;  3KRF A;  3WCC A;  5IVG A;  3ZCD A;  5IL8 A;  4LFV F;  1V4J A;  1KIZ A;  3TS7 A;  1FPS A;  1WKZ A;  1PS1 A;  1YHL A;  5ILK A;  3BNX A;  1VG6 A;  5ILY A;  4XQT F;  4LTZ A;  3PYA A;  2ZCQ A;  4QPF A;  4UMJ A;  1N20 A;  3SAE A;  2FOR A;  5ER8 A;  4Q23 A;  3APZ A;  3LDW A;  5E8K A;  5ERM A;  3AE0 A;  3KRP B;  4FP4 A;  2P1C A;  3CKE A;  1UBW A;  4RXD A;  3LJI A;  3LG5 A;  2AET A;  5DJR F;  3MAV A;  2Q9Y A;  4NKF A;  5A0J A;  3WJK A;  3ID0 A;  2E94 A;  4KKM A;  3KRF B;  4NUA A;  4OKZ A;  1WL0 A;  5HNA A;  2AZJ A;  4E9U A;  2F92 F;  5IN8 A;  3N46 F;  4LPG F;  3ZMB A;  4GP1 A;  2Q80 A;  3WCI A;  1YQ7 A;  1HM4 A;  4EA0 A;  3N5H F;  5IKH A;  4KK2 A;  3PDE A;  2Z4W A;  3QKC A;  2F9K F;  3WCH A;  1WMW A;  5C05 A;  5JUZ F;  3WCF A;  3NF2 A;  3ZMC A;  1RTR A;  3ICZ A;  4E9Z A;  3N6K F;  3SDT A;  4JXN A;  3BNY A;  4KWD A;  3VJ9 A;  4LZ0 A;  2ZCO A;  1RQJ A;  3ICN A;  1YYQ A;  1VG7 A;  3EFQ A;  3ACW A;  3N0F A;  4XQR F;  5JA0 F;  4RXE A;  5I1U A;  3WCA A;  4KPD A;  1DGP A;  4RXC A;  1RQI A;  2Z4Z A;  3NPR A;  4N9U A;  4FJQ A;  2F8Z F;  3ACY A;  2PS6 A;  3LZ9 A;  5A0I A;  3Q2Q A;  3V66 A;  3B7L A;  3SDR A;  2H8O A;  4KQS A;  1V4E A;  1VG2 A;  3Q1O A;  4JZX A;  2Z7I A;  5JV0 F;  1YHM A;  5B0M A;  2PS8 A;  2OGD A;  1YYR A;  4LIX A;  3EZ3 A;  5B0I A;  3ADZ A;  4GAX A;  5CG6 A;  2E8T A;  3DYF A;  3SDQ A;  2Z78 A;  1N23 A;  2E91 A;  2E90 A;  4MC0 A;  4F6V A;  2Z4X A;  5DHK A;  5B0L A;  5B00 A;  4DEM F;  3RYW A;  1WY0 A;  1YYT A;  4F62 A;  1V4K A;  5JV2 F;  3WJN A;  4LZ3 A;  4P0V A;  3TC1 A;  5ERN A;  4HD1 A;  3P5P A;  2EWG A;  1N21 A;  4JXY A;  4QXS F;  3KBK A;  1N1B A;  4JVJ F;  4LA5 A;  4KVW A;  3LOM A;  3LEE A;  3WSB A;  3M02 A;  4LZC A;  4JZB A;  5DGM F;  2J5C A;  2J1O A;  2ZEU A;  3EGT A;  3M9U A;  5EAT A;  2E8W A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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