3ICNA

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with isopentenyl pyrophosphate and 3-fluoro-1-(2-hydroxy-2,2-bis-phosphono-ethyl)-pyridinium
Total Genus 148
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
148
sequence length
362
structure length
362
Chain Sequence
MASMERFLSVYDEVQAFLLDQLQSKYEIDPNRARYLRIMMDTTCLGGKYFRGMTVVNVAEGFLAVTQHDEATKERILHDACVGGWMIEFLQAHYLVEDDIMDGSVMRRGKPCWYRFPGVTTQCAINDGIILKSWTQIMAWHYFADRPFLKDLLCLFQKVDYATAVGQMYDVTSMCDSNKLDPEVAQPMTTDFAEFTPAIYKRIVKYKTTFYTYLLPLVMGLFVSEAAASVEMNLVERVAHLIGEYFQVQDDVMDCFTPPEQLGKVGTDIEDAKCSWLAVTFLGKANAAQVAEFKANYGDKDPAKVAVVKRLYSEANLQADFAAYEAEVVREVESLIEQLKVKSPTFAESVAVVWEKTHKRKK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase
molecule keywords Farnesyl pyrophosphate synthase
publication title Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer.
pubmed doi rcsb
source organism Trypanosoma cruzi
total genus 148
structure length 362
sequence length 362
ec nomenclature ec 2.5.1.10: (2E,6E)-farnesyl diphosphate synthase.
pdb deposition date 2009-07-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3icnA00
2OA6A 4P0WA 3N0GA 1WMWA 5JUZF 1HM4A 4KFAA 4OGUA 2Z4VA 4FP4A 3WCAA 3CP6A 3LG5A 1WY0A 3V66A 3ADZA 4P0XA 3WEIA 5B02A 3TFVA 4JZBA 4LZ0A 4F6XA 3OYRA 5E8LA 2PS5A 3W7FA 3CC9A 3V1XA 1V4HA 3M0GA 5ILYA 5IMNA 2P1CA 5HN7A 5AELA 3G4DA 3G4FA 4LPGF 4LTZA 3WJOA 4LXWA 4L2XF 2H8OA 4UMJA 5B00A 4EA2A 4GP1A 2Q9ZA 3KBKA 4JYXA 2E90A 3PKOA 3WCHA 4KVYA 2OPNA 3AE0A 1N23A 4H5CF 3SDUA 1RQJA 5ILDA 3ZMBA 2E8XA 4K10A 4LA6A 3WCJA 3LEEA 3SAEA 3VJBA 5B0IA 3WJNA 2Q58A 5E8HA 2E8TA 4E1EA 5IL3A 1YYTA 3VJ8A 2AEKA 2ONGA 5I1UA 1HXGA 2Q80A 2FTZA 2OPMA 1YYUA 3OACB 2AZKA 3WC9A 4GA3A 1FPSA 3RBMA 4KQ5A 3CKEA 4WK5A 3N3LF 3ICKA 4DZWA 2F94F 3LLWA 4XQRF 4DWBA 3KRFA 3VJEA 2E92A 3RMGA 4NFJF 4PVYF 4LFGA 5IMIA 2AETA 5IKAA 3N0FA 2O1OA 3NPKA 3Q30A 4OMHA 4LZ3A 3WEJA 3WEFA 1VG4A 2E91A 5ILZA 2E8VA 3N6KF 2F7MF 3Q2ZA 5C05A 3OABA 3QKCA 1YJ4A 3PH7A 2VF6A 3P5PA 3WJKA 5IL8A 1YQ7A 4GP2A 3KROB 5DJVF 3LZ9A 3N1WF 4KUXA 4ZQ8A 4DXJA 1DI1A 3PYAA 2ZCRA 3LOMA 5B0LA 4NG6A 3TFPA 4MC0A 5DIQF 5B03A 3EGTA 3NF2A 2PS7A 5E8KA 3WSBA 5A0KA 3ACYA 2OGDA 4QPFA 1YYSA 3AQBB 3KRAA 1DGPA 1UBVA 2Z7IA 4NFKF 3VJCA 3WEGA 4JZXA 2J1OA 5IM1A 2AZLA 1JFAA 3SDVA 3KRPB 5DHIA 3WSAA 4KPDA 4HD1A 2DH4A 2PS4A 3NPRA 3WCIA 2Z7HA 1EZFA 3ICMA 3M01A 3SDTA 3TFNA 4RXDA 4DEMF 3MZVA 3V1VA 3M00A 5DJRF 5CG6A 5JV2F 4KWDA 5IK9A 1N22A 4NUAA 2EWGA 3N45F 2F92F 5JV0F 3Q1OA 3P8LA 1UBYA 1YYRA 5IKHA 3RYWA 3LSNA 4DWGA 5ILJA 5KSXF 4LLTA 3SDQA 4F62A 1YV5A 1RTRA 3P8RA 4OKZA 3ASXA 1RQIA 3QQVA 1VG3A 3N46F 1VG7A 4JVJF 2FORA 2PS8A 4OMGA 3LGZB 3ZOUA 3UCAA 3BNYA 4KVIA 1YYQA 3ID0A 5JV1F 3KRCA 5H9DA 3TC1A 2ZCQA 3TS7A 3B7LA 3PYBA 2F9KF 2I19A 5DZ2A 1HXCA 1N20A 4NKEA 3ZMCA 4KVDA 3BNXA 5EASA 1PS1A 4LA5A 2J5CA 4RYPA 4F6VA 4P0VA 5B0KA 5JA0F 1YHMA 4DI5A 2E93A 1WL1A 3VJAA 1VG2A 5DGSF 5DJPF 4LIXA 5B0MA 3N49F 3AQ0A 3P5RA 4MC3A 5B01A 4MC8A 2Z4XA 3S4JA 5ERMA 3LDWA 5ILKA 3M02A 5EATA 5B0JA 2E4OA 2ZY1A 2Q9YA 5EROA 3EFQA 2J1PA 4N9UA 5EAUA 4EA1A 3WCEA 5DW7A 3IBAA 4NFIF 2ZEVA 3APZA 3LMDA 3N5HF 1HX9A 4LFEA 3OACA 3M9UA 5IVGA 1YHLA 3LK5A 4KQUA 2QISA 5HNAA 4KVWA 5HN8A 4LTVA 2RAHA 5CG5A 3WCBA 5A0JA 3EZ3A 2F89F 1WL0A 3ACXA 5AFXA 4FJQA 2AELA 1N1ZA 3N1VF 1V4JA 3ZL6A 5DHKA 3WCCA 4JXYA 4RXEA 3KRCB 4RXAA 3NRIA 3KRFB 4E9UA 1N1BA 3LVSA 4JXNA 2ZCSA 4KQSA 2AZJA 1HM7A 3N5JF 3VJ9A 1UBXA 4RXCA 3DYFA 4GAXA 3VJDA 3KB9A 3WCDA 2E8UA 3WE9A 4H5DF 3AQCB 5AYPA 5ILHA 1UBWA 1ZW5A 1V4IA 4QXSF 3DYGA 1KIZA 3OABB 3KROA 5IN8A 4NKFA 4Q23A 2E94A 3RYEA 3IPIA 1N24A 1V4EA 2PS6A 3WCMA 1JFGA 2F8ZF 5ER8A 3SDRA 5IMPA 4KK2A 4LFVF 3ACWA 5HN9A 5DGNF 3WCGA 2E8WA 5IK6A 2Z52A 4H5EF 2F8CF 4DHDA 2Z78A 3LGKA 1N21A 4LLSA 3P41A 3ZCDA 5A0IA 2Z4YA 4XQTF 3KRPA 2ZCOA 3KRAB 4LOBA 4E9ZA 3Q2QA 3WEHA 5ERNA 3WEKA 3LJIA 3MAVA 4XQSF 2ZEUA 2Z4WA 4RNQA 5IK0A 3DYHA 4KKMA 3WCFA 4LZCA 1WL3A 4OKMA 1HXAA 2Z4ZA 4LUUA 3PDEA 2E95A 4KPJA 3N3DA 2ONHA 4PVXF 2Z50A 1KIYA 4LPHF 4N1ZF 1WKZA 5AHUB 3ICNA 1WL2A 3S9VA 1VG6A 4EA0A 5DGMF 3WCLA 5ILIA 1YHKA 3ICZA 1V4KA
chains in the Genus database with same CATH superfamily
2OA6A 4P0WA 3N0GA 1WMWA 5JUZF 1HM4A 4KFAA 4OGUA 2Z4VA 4FP4A 3WCAA 3CP6A 3LG5A 1WY0A 3V66A 3ADZA 4P0XA 3WEIA 5B02A 3TFVA 4JZBA 4LZ0A 4F6XA 3OYRA 5E8LA 2PS5A 3W7FA 3CC9A 3V1XA 1V4HA 3M0GA 5ILYA 5IMNA 2P1CA 5HN7A 5AELA 3G4DA 3G4FA 4LPGF 4LTZA 3WJOA 4LXWA 4L2XF 2H8OA 4UMJA 5B00A 4EA2A 4GP1A 2Q9ZA 3KBKA 4JYXA 2E90A 3PKOA 3WCHA 4KVYA 2OPNA 3AE0A 1N23A 4H5CF 3SDUA 1RQJA 5ILDA 3ZMBA 2E8XA 4K10A 4LA6A 3WCJA 3LEEA 3SAEA 3VJBA 5B0IA 3WJNA 2Q58A 5E8HA 2E8TA 4E1EA 5IL3A 1YYTA 3VJ8A 2AEKA 2ONGA 5I1UA 1HXGA 2Q80A 2FTZA 2OPMA 1YYUA 3OACB 2AZKA 3WC9A 4GA3A 1FPSA 3RBMA 4KQ5A 3CKEA 4WK5A 3N3LF 3ICKA 4DZWA 2F94F 3LLWA 4XQRF 4DWBA 3KRFA 3VJEA 2E92A 3RMGA 4NFJF 4PVYF 4LFGA 5IMIA 2AETA 5IKAA 3N0FA 2O1OA 3NPKA 3Q30A 4OMHA 4LZ3A 3WEJA 3WEFA 1VG4A 2E91A 5ILZA 2E8VA 3N6KF 2F7MF 3Q2ZA 5C05A 3OABA 3QKCA 1YJ4A 3PH7A 2VF6A 3P5PA 3WJKA 5IL8A 1YQ7A 4GP2A 3KROB 5DJVF 3LZ9A 3N1WF 4KUXA 4ZQ8A 4DXJA 1DI1A 3PYAA 2ZCRA 3LOMA 5B0LA 4NG6A 3TFPA 4MC0A 5DIQF 5B03A 3EGTA 3NF2A 2PS7A 5E8KA 3WSBA 5A0KA 3ACYA 2OGDA 4QPFA 1YYSA 3AQBB 3KRAA 1DGPA 1UBVA 2Z7IA 4NFKF 3VJCA 3WEGA 4JZXA 2J1OA 5IM1A 2AZLA 1JFAA 3SDVA 3KRPB 5DHIA 3WSAA 4KPDA 4HD1A 2DH4A 2PS4A 3NPRA 3WCIA 2Z7HA 1EZFA 3ICMA 3M01A 3SDTA 3TFNA 4RXDA 4DEMF 3MZVA 3V1VA 3M00A 5DJRF 5CG6A 5JV2F 4KWDA 5IK9A 1N22A 4NUAA 2EWGA 3N45F 2F92F 5JV0F 3Q1OA 3P8LA 1UBYA 1YYRA 5IKHA 3RYWA 3LSNA 4DWGA 5ILJA 5KSXF 4LLTA 3SDQA 4F62A 1YV5A 1RTRA 3P8RA 4OKZA 3ASXA 1RQIA 3QQVA 1VG3A 3N46F 1VG7A 4JVJF 2FORA 2PS8A 4OMGA 3LGZB 3ZOUA 3UCAA 3BNYA 4KVIA 1YYQA 3ID0A 5JV1F 3KRCA 5H9DA 3TC1A 2ZCQA 3TS7A 3B7LA 3PYBA 2F9KF 2I19A 5DZ2A 1HXCA 1N20A 4NKEA 3ZMCA 4KVDA 3BNXA 5EASA 1PS1A 4LA5A 2J5CA 4RYPA 4F6VA 4P0VA 5B0KA 5JA0F 1YHMA 4DI5A 2E93A 1WL1A 3VJAA 1VG2A 5DGSF 5DJPF 4LIXA 5B0MA 3N49F 3AQ0A 3P5RA 4MC3A 5B01A 4MC8A 2Z4XA 3S4JA 5ERMA 3LDWA 5ILKA 3M02A 5EATA 5B0JA 2E4OA 2ZY1A 2Q9YA 5EROA 3EFQA 2J1PA 4N9UA 5EAUA 4EA1A 3WCEA 5DW7A 3IBAA 4NFIF 2ZEVA 3APZA 3LMDA 3N5HF 1HX9A 4LFEA 3OACA 3M9UA 5IVGA 1YHLA 3LK5A 4KQUA 2QISA 5HNAA 4KVWA 5HN8A 4LTVA 2RAHA 5CG5A 3WCBA 5A0JA 3EZ3A 2F89F 1WL0A 3ACXA 5AFXA 4FJQA 2AELA 1N1ZA 3N1VF 1V4JA 3ZL6A 5DHKA 3WCCA 4JXYA 4RXEA 3KRCB 4RXAA 3NRIA 3KRFB 4E9UA 1N1BA 3LVSA 4JXNA 2ZCSA 4KQSA 2AZJA 1HM7A 3N5JF 3VJ9A 1UBXA 4RXCA 3DYFA 4GAXA 3VJDA 3KB9A 3WCDA 2E8UA 3WE9A 4H5DF 3AQCB 5AYPA 5ILHA 1UBWA 1ZW5A 1V4IA 4QXSF 3DYGA 1KIZA 3OABB 3KROA 5IN8A 4NKFA 4Q23A 2E94A 3RYEA 3IPIA 1N24A 1V4EA 2PS6A 3WCMA 1JFGA 2F8ZF 5ER8A 3SDRA 5IMPA 4KK2A 4LFVF 3ACWA 5HN9A 5DGNF 3WCGA 2E8WA 5IK6A 2Z52A 4H5EF 2F8CF 4DHDA 2Z78A 3LGKA 1N21A 4LLSA 3P41A 3ZCDA 5A0IA 2Z4YA 4XQTF 3KRPA 2ZCOA 3KRAB 4LOBA 4E9ZA 3Q2QA 3WEHA 5ERNA 3WEKA 3LJIA 3MAVA 4XQSF 2ZEUA 2Z4WA 4RNQA 5IK0A 3DYHA 4KKMA 3WCFA 4LZCA 1WL3A 4OKMA 1HXAA 2Z4ZA 4LUUA 3PDEA 2E95A 4KPJA 3N3DA 2ONHA 4PVXF 2Z50A 1KIYA 4LPHF 4N1ZF 1WKZA 5AHUB 3ICNA 1WL2A 3S9VA 1VG6A 4EA0A 5DGMF 3WCLA 5ILIA 1YHKA 3ICZA 1V4KA
chains in the Genus database with same CATH topology
2OA6A 4P0WA 3N0GA 1WMWA 5JUZF 1HM4A 4KFAA 4OGUA 2Z4VA 4FP4A 3WCAA 3CP6A 3LG5A 1WY0A 3V66A 3ADZA 4P0XA 3WEIA 5B02A 3TFVA 4JZBA 4LZ0A 4F6XA 3OYRA 5E8LA 2PS5A 3W7FA 3CC9A 3V1XA 1V4HA 3M0GA 5ILYA 5IMNA 2P1CA 5HN7A 5AELA 3G4DA 3G4FA 4LPGF 4LTZA 3WJOA 4LXWA 4L2XF 2H8OA 4UMJA 5B00A 4EA2A 4GP1A 2Q9ZA 3KBKA 4JYXA 2E90A 3PKOA 3WCHA 4KVYA 2OPNA 3AE0A 1N23A 4H5CF 3SDUA 1RQJA 5ILDA 3ZMBA 2E8XA 4K10A 4LA6A 3WCJA 3LEEA 3SAEA 3VJBA 5B0IA 3WJNA 2Q58A 5E8HA 2E8TA 4E1EA 5IL3A 1YYTA 3VJ8A 2AEKA 2ONGA 5I1UA 1HXGA 2Q80A 2FTZA 2OPMA 1YYUA 3OACB 2AZKA 3WC9A 4GA3A 1FPSA 3RBMA 4KQ5A 3CKEA 4WK5A 3N3LF 3ICKA 4DZWA 2F94F 3LLWA 4XQRF 4DWBA 3KRFA 3VJEA 2E92A 3RMGA 4NFJF 4PVYF 4LFGA 5IMIA 2AETA 5IKAA 3N0FA 2O1OA 3NPKA 3Q30A 4OMHA 4LZ3A 3WEJA 3WEFA 1VG4A 2E91A 5ILZA 2E8VA 3N6KF 2F7MF 3Q2ZA 5C05A 3OABA 3QKCA 1YJ4A 3PH7A 2VF6A 3P5PA 3WJKA 5IL8A 1YQ7A 4GP2A 3KROB 5DJVF 3LZ9A 3N1WF 4KUXA 4ZQ8A 4DXJA 1DI1A 3PYAA 2ZCRA 3LOMA 5B0LA 4NG6A 3TFPA 4MC0A 5DIQF 5B03A 3EGTA 3NF2A 2PS7A 5E8KA 3WSBA 5A0KA 3ACYA 2OGDA 4QPFA 1YYSA 3AQBB 3KRAA 1DGPA 1UBVA 2Z7IA 4NFKF 3VJCA 3WEGA 4JZXA 2J1OA 5IM1A 2AZLA 1JFAA 3SDVA 3KRPB 5DHIA 3WSAA 4KPDA 4HD1A 2DH4A 2PS4A 3NPRA 3WCIA 2Z7HA 1EZFA 3ICMA 3M01A 3SDTA 3TFNA 4RXDA 4DEMF 3MZVA 3V1VA 3M00A 5DJRF 5CG6A 5JV2F 4KWDA 5IK9A 1N22A 4NUAA 2EWGA 3N45F 2F92F 5JV0F 3Q1OA 3P8LA 1UBYA 1YYRA 5IKHA 3RYWA 3LSNA 4DWGA 5ILJA 5KSXF 4LLTA 3SDQA 4F62A 1YV5A 1RTRA 3P8RA 4OKZA 3ASXA 1RQIA 3QQVA 1VG3A 3N46F 1VG7A 4JVJF 2FORA 2PS8A 4OMGA 3LGZB 3ZOUA 3UCAA 3BNYA 4KVIA 1YYQA 3ID0A 5JV1F 3KRCA 5H9DA 3TC1A 2ZCQA 3TS7A 3B7LA 3PYBA 2F9KF 2I19A 5DZ2A 1HXCA 1N20A 4NKEA 3ZMCA 4KVDA 3BNXA 5EASA 1PS1A 4LA5A 2J5CA 4RYPA 4F6VA 4P0VA 5B0KA 5JA0F 1YHMA 4DI5A 2E93A 1WL1A 3VJAA 1VG2A 5DGSF 5DJPF 4LIXA 5B0MA 3N49F 3AQ0A 3P5RA 4MC3A 5B01A 4MC8A 2Z4XA 3S4JA 5ERMA 3LDWA 5ILKA 3M02A 5EATA 5B0JA 2E4OA 2ZY1A 2Q9YA 5EROA 3EFQA 2J1PA 4N9UA 5EAUA 4EA1A 3WCEA 5DW7A 3IBAA 4NFIF 2ZEVA 3APZA 3LMDA 3N5HF 1HX9A 4LFEA 3OACA 3M9UA 5IVGA 1YHLA 3LK5A 4KQUA 2QISA 5HNAA 4KVWA 5HN8A 4LTVA 2RAHA 5CG5A 3WCBA 5A0JA 3EZ3A 2F89F 1WL0A 3ACXA 5AFXA 4FJQA 2AELA 1N1ZA 3N1VF 1V4JA 3ZL6A 5DHKA 3WCCA 4JXYA 4RXEA 3KRCB 4RXAA 3NRIA 3KRFB 4E9UA 1N1BA 3LVSA 4JXNA 2ZCSA 4KQSA 2AZJA 1HM7A 3N5JF 3VJ9A 1UBXA 4RXCA 3DYFA 4GAXA 3VJDA 3KB9A 3WCDA 2E8UA 3WE9A 4H5DF 3AQCB 5AYPA 5ILHA 1UBWA 1ZW5A 1V4IA 4QXSF 3DYGA 1KIZA 3OABB 3KROA 5IN8A 4NKFA 4Q23A 2E94A 3RYEA 3IPIA 1N24A 1V4EA 2PS6A 3WCMA 1JFGA 2F8ZF 5ER8A 3SDRA 5IMPA 4KK2A 4LFVF 3ACWA 5HN9A 5DGNF 3WCGA 2E8WA 5IK6A 2Z52A 4H5EF 2F8CF 4DHDA 2Z78A 3LGKA 1N21A 4LLSA 3P41A 3ZCDA 5A0IA 2Z4YA 4XQTF 3KRPA 2ZCOA 3KRAB 4LOBA 4E9ZA 3Q2QA 3WEHA 5ERNA 3WEKA 3LJIA 3MAVA 4XQSF 2ZEUA 2Z4WA 4RNQA 5IK0A 3DYHA 4KKMA 3WCFA 4LZCA 1WL3A 4OKMA 1HXAA 2Z4ZA 4LUUA 3PDEA 2E95A 4KPJA 3N3DA 2ONHA 4PVXF 2Z50A 1KIYA 4LPHF 4N1ZF 1WKZA 5AHUB 3ICNA 1WL2A 3S9VA 1VG6A 4EA0A 5DGMF 3WCLA 5ILIA 1YHKA 3ICZA 1V4KA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2OA6 A;  4P0W A;  3N0G A;  1WMW A;  5JUZ F;  1HM4 A;  4KFA A;  4OGU A;  2Z4V A;  4FP4 A;  3WCA A;  3CP6 A;  3LG5 A;  1WY0 A;  3V66 A;  3ADZ A;  4P0X A;  3WEI A;  5B02 A;  3TFV A;  4JZB A;  4LZ0 A;  4F6X A;  3OYR A;  5E8L A;  2PS5 A;  3W7F A;  3CC9 A;  3V1X A;  1V4H A;  3M0G A;  5ILY A;  5IMN A;  2P1C A;  5HN7 A;  5AEL A;  3G4D A;  3G4F A;  4LPG F;  4LTZ A;  3WJO A;  4LXW A;  4L2X F;  2H8O A;  4UMJ A;  5B00 A;  4EA2 A;  4GP1 A;  2Q9Z A;  3KBK A;  4JYX A;  2E90 A;  3PKO A;  3WCH A;  4KVY A;  2OPN A;  3AE0 A;  1N23 A;  4H5C F;  3SDU A;  1RQJ A;  5ILD A;  3ZMB A;  2E8X A;  4K10 A;  4LA6 A;  3WCJ A;  3LEE A;  3SAE A;  3VJB A;  5B0I A;  3WJN A;  2Q58 A;  5E8H A;  2E8T A;  4E1E A;  5IL3 A;  1YYT A;  3VJ8 A;  2AEK A;  2ONG A;  5I1U A;  1HXG A;  2Q80 A;  2FTZ A;  2OPM A;  1YYU A;  3OAC B;  2AZK A;  3WC9 A;  4GA3 A;  1FPS A;  3RBM A;  4KQ5 A;  3CKE A;  4WK5 A;  3N3L F;  3ICK A;  4DZW A;  2F94 F;  3LLW A;  4XQR F;  4DWB A;  3KRF A;  3VJE A;  2E92 A;  3RMG A;  4NFJ F;  4PVY F;  4LFG A;  5IMI A;  2AET A;  5IKA A;  3N0F A;  2O1O A;  3NPK A;  3Q30 A;  4OMH A;  4LZ3 A;  3WEJ A;  3WEF A;  1VG4 A;  2E91 A;  5ILZ A;  2E8V A;  3N6K F;  2F7M F;  3Q2Z A;  5C05 A;  3OAB A;  3QKC A;  1YJ4 A;  3PH7 A;  2VF6 A;  3P5P A;  3WJK A;  5IL8 A;  1YQ7 A;  4GP2 A;  3KRO B;  5DJV F;  3LZ9 A;  3N1W F;  4KUX A;  4ZQ8 A;  4DXJ A;  1DI1 A;  3PYA A;  2ZCR A;  3LOM A;  5B0L A;  4NG6 A;  3TFP A;  4MC0 A;  5DIQ F;  5B03 A;  3EGT A;  3NF2 A;  2PS7 A;  5E8K A;  3WSB A;  5A0K A;  3ACY A;  2OGD A;  4QPF A;  1YYS A;  3AQB B;  3KRA A;  1DGP A;  1UBV A;  2Z7I A;  4NFK F;  3VJC A;  3WEG A;  4JZX A;  2J1O A;  5IM1 A;  2AZL A;  1JFA A;  3SDV A;  3KRP B;  5DHI A;  3WSA A;  4KPD A;  4HD1 A;  2DH4 A;  2PS4 A;  3NPR A;  3WCI A;  2Z7H A;  1EZF A;  3ICM A;  3M01 A;  3SDT A;  3TFN A;  4RXD A;  4DEM F;  3MZV A;  3V1V A;  3M00 A;  5DJR F;  5CG6 A;  5JV2 F;  4KWD A;  5IK9 A;  1N22 A;  4NUA A;  2EWG A;  3N45 F;  2F92 F;  5JV0 F;  3Q1O A;  3P8L A;  1UBY A;  1YYR A;  5IKH A;  3RYW A;  3LSN A;  4DWG A;  5ILJ A;  5KSX F;  4LLT A;  3SDQ A;  4F62 A;  1YV5 A;  1RTR A;  3P8R A;  4OKZ A;  3ASX A;  1RQI A;  3QQV A;  1VG3 A;  3N46 F;  1VG7 A;  4JVJ F;  2FOR A;  2PS8 A;  4OMG A;  3LGZ B;  3ZOU A;  3UCA A;  3BNY A;  4KVI A;  1YYQ A;  3ID0 A;  5JV1 F;  3KRC A;  5H9D A;  3TC1 A;  2ZCQ A;  3TS7 A;  3B7L A;  3PYB A;  2F9K F;  2I19 A;  5DZ2 A;  1HXC A;  1N20 A;  4NKE A;  3ZMC A;  4KVD A;  3BNX A;  5EAS A;  1PS1 A;  4LA5 A;  2J5C A;  4RYP A;  4F6V A;  4P0V A;  5B0K A;  5JA0 F;  1YHM A;  4DI5 A;  2E93 A;  1WL1 A;  3VJA A;  1VG2 A;  5DGS F;  5DJP F;  4LIX A;  5B0M A;  3N49 F;  3AQ0 A;  3P5R A;  4MC3 A;  5B01 A;  4MC8 A;  2Z4X A;  3S4J A;  5ERM A;  3LDW A;  5ILK A;  3M02 A;  5EAT A;  5B0J A;  2E4O A;  2ZY1 A;  2Q9Y A;  5ERO A;  3EFQ A;  2J1P A;  4N9U A;  5EAU A;  4EA1 A;  3WCE A;  5DW7 A;  3IBA A;  4NFI F;  2ZEV A;  3APZ A;  3LMD A;  3N5H F;  1HX9 A;  4LFE A;  3OAC A;  3M9U A;  5IVG A;  1YHL A;  3LK5 A;  4KQU A;  2QIS A;  5HNA A;  4KVW A;  5HN8 A;  4LTV A;  2RAH A;  5CG5 A;  3WCB A;  5A0J A;  3EZ3 A;  2F89 F;  1WL0 A;  3ACX A;  5AFX A;  4FJQ A;  2AEL A;  1N1Z A;  3N1V F;  1V4J A;  3ZL6 A;  5DHK A;  3WCC A;  4JXY A;  4RXE A;  3KRC B;  4RXA A;  3NRI A;  3KRF B;  4E9U A;  1N1B A;  3LVS A;  4JXN A;  2ZCS A;  4KQS A;  2AZJ A;  1HM7 A;  3N5J F;  3VJ9 A;  1UBX A;  4RXC A;  3DYF A;  4GAX A;  3VJD A;  3KB9 A;  3WCD A;  2E8U A;  3WE9 A;  4H5D F;  3AQC B;  5AYP A;  5ILH A;  1UBW A;  1ZW5 A;  1V4I A;  4QXS F;  3DYG A;  1KIZ A;  3OAB B;  3KRO A;  5IN8 A;  4NKF A;  4Q23 A;  2E94 A;  3RYE A;  3IPI A;  1N24 A;  1V4E A;  2PS6 A;  3WCM A;  1JFG A;  2F8Z F;  5ER8 A;  3SDR A;  5IMP A;  4KK2 A;  4LFV F;  3ACW A;  5HN9 A;  5DGN F;  3WCG A;  2E8W A;  5IK6 A;  2Z52 A;  4H5E F;  2F8C F;  4DHD A;  2Z78 A;  3LGK A;  1N21 A;  4LLS A;  3P41 A;  3ZCD A;  5A0I A;  2Z4Y A;  4XQT F;  3KRP A;  2ZCO A;  3KRA B;  4LOB A;  4E9Z A;  3Q2Q A;  3WEH A;  5ERN A;  3WEK A;  3LJI A;  3MAV A;  4XQS F;  2ZEU A;  2Z4W A;  4RNQ A;  5IK0 A;  3DYH A;  4KKM A;  3WCF A;  4LZC A;  1WL3 A;  4OKM A;  1HXA A;  2Z4Z A;  4LUU A;  3PDE A;  2E95 A;  4KPJ A;  3N3D A;  2ONH A;  4PVX F;  2Z50 A;  1KIY A;  4LPH F;  4N1Z F;  1WKZ A;  5AHU B;  3ICN A;  1WL2 A;  3S9V A;  1VG6 A;  4EA0 A;  5DGM F;  3WCL A;  5ILI A;  1YHK A;  3ICZ A;  1V4K A; 
#chains in the Genus database with same CATH topology
 2OA6 A;  4P0W A;  3N0G A;  1WMW A;  5JUZ F;  1HM4 A;  4KFA A;  4OGU A;  2Z4V A;  4FP4 A;  3WCA A;  3CP6 A;  3LG5 A;  1WY0 A;  3V66 A;  3ADZ A;  4P0X A;  3WEI A;  5B02 A;  3TFV A;  4JZB A;  4LZ0 A;  4F6X A;  3OYR A;  5E8L A;  2PS5 A;  3W7F A;  3CC9 A;  3V1X A;  1V4H A;  3M0G A;  5ILY A;  5IMN A;  2P1C A;  5HN7 A;  5AEL A;  3G4D A;  3G4F A;  4LPG F;  4LTZ A;  3WJO A;  4LXW A;  4L2X F;  2H8O A;  4UMJ A;  5B00 A;  4EA2 A;  4GP1 A;  2Q9Z A;  3KBK A;  4JYX A;  2E90 A;  3PKO A;  3WCH A;  4KVY A;  2OPN A;  3AE0 A;  1N23 A;  4H5C F;  3SDU A;  1RQJ A;  5ILD A;  3ZMB A;  2E8X A;  4K10 A;  4LA6 A;  3WCJ A;  3LEE A;  3SAE A;  3VJB A;  5B0I A;  3WJN A;  2Q58 A;  5E8H A;  2E8T A;  4E1E A;  5IL3 A;  1YYT A;  3VJ8 A;  2AEK A;  2ONG A;  5I1U A;  1HXG A;  2Q80 A;  2FTZ A;  2OPM A;  1YYU A;  3OAC B;  2AZK A;  3WC9 A;  4GA3 A;  1FPS A;  3RBM A;  4KQ5 A;  3CKE A;  4WK5 A;  3N3L F;  3ICK A;  4DZW A;  2F94 F;  3LLW A;  4XQR F;  4DWB A;  3KRF A;  3VJE A;  2E92 A;  3RMG A;  4NFJ F;  4PVY F;  4LFG A;  5IMI A;  2AET A;  5IKA A;  3N0F A;  2O1O A;  3NPK A;  3Q30 A;  4OMH A;  4LZ3 A;  3WEJ A;  3WEF A;  1VG4 A;  2E91 A;  5ILZ A;  2E8V A;  3N6K F;  2F7M F;  3Q2Z A;  5C05 A;  3OAB A;  3QKC A;  1YJ4 A;  3PH7 A;  2VF6 A;  3P5P A;  3WJK A;  5IL8 A;  1YQ7 A;  4GP2 A;  3KRO B;  5DJV F;  3LZ9 A;  3N1W F;  4KUX A;  4ZQ8 A;  4DXJ A;  1DI1 A;  3PYA A;  2ZCR A;  3LOM A;  5B0L A;  4NG6 A;  3TFP A;  4MC0 A;  5DIQ F;  5B03 A;  3EGT A;  3NF2 A;  2PS7 A;  5E8K A;  3WSB A;  5A0K A;  3ACY A;  2OGD A;  4QPF A;  1YYS A;  3AQB B;  3KRA A;  1DGP A;  1UBV A;  2Z7I A;  4NFK F;  3VJC A;  3WEG A;  4JZX A;  2J1O A;  5IM1 A;  2AZL A;  1JFA A;  3SDV A;  3KRP B;  5DHI A;  3WSA A;  4KPD A;  4HD1 A;  2DH4 A;  2PS4 A;  3NPR A;  3WCI A;  2Z7H A;  1EZF A;  3ICM A;  3M01 A;  3SDT A;  3TFN A;  4RXD A;  4DEM F;  3MZV A;  3V1V A;  3M00 A;  5DJR F;  5CG6 A;  5JV2 F;  4KWD A;  5IK9 A;  1N22 A;  4NUA A;  2EWG A;  3N45 F;  2F92 F;  5JV0 F;  3Q1O A;  3P8L A;  1UBY A;  1YYR A;  5IKH A;  3RYW A;  3LSN A;  4DWG A;  5ILJ A;  5KSX F;  4LLT A;  3SDQ A;  4F62 A;  1YV5 A;  1RTR A;  3P8R A;  4OKZ A;  3ASX A;  1RQI A;  3QQV A;  1VG3 A;  3N46 F;  1VG7 A;  4JVJ F;  2FOR A;  2PS8 A;  4OMG A;  3LGZ B;  3ZOU A;  3UCA A;  3BNY A;  4KVI A;  1YYQ A;  3ID0 A;  5JV1 F;  3KRC A;  5H9D A;  3TC1 A;  2ZCQ A;  3TS7 A;  3B7L A;  3PYB A;  2F9K F;  2I19 A;  5DZ2 A;  1HXC A;  1N20 A;  4NKE A;  3ZMC A;  4KVD A;  3BNX A;  5EAS A;  1PS1 A;  4LA5 A;  2J5C A;  4RYP A;  4F6V A;  4P0V A;  5B0K A;  5JA0 F;  1YHM A;  4DI5 A;  2E93 A;  1WL1 A;  3VJA A;  1VG2 A;  5DGS F;  5DJP F;  4LIX A;  5B0M A;  3N49 F;  3AQ0 A;  3P5R A;  4MC3 A;  5B01 A;  4MC8 A;  2Z4X A;  3S4J A;  5ERM A;  3LDW A;  5ILK A;  3M02 A;  5EAT A;  5B0J A;  2E4O A;  2ZY1 A;  2Q9Y A;  5ERO A;  3EFQ A;  2J1P A;  4N9U A;  5EAU A;  4EA1 A;  3WCE A;  5DW7 A;  3IBA A;  4NFI F;  2ZEV A;  3APZ A;  3LMD A;  3N5H F;  1HX9 A;  4LFE A;  3OAC A;  3M9U A;  5IVG A;  1YHL A;  3LK5 A;  4KQU A;  2QIS A;  5HNA A;  4KVW A;  5HN8 A;  4LTV A;  2RAH A;  5CG5 A;  3WCB A;  5A0J A;  3EZ3 A;  2F89 F;  1WL0 A;  3ACX A;  5AFX A;  4FJQ A;  2AEL A;  1N1Z A;  3N1V F;  1V4J A;  3ZL6 A;  5DHK A;  3WCC A;  4JXY A;  4RXE A;  3KRC B;  4RXA A;  3NRI A;  3KRF B;  4E9U A;  1N1B A;  3LVS A;  4JXN A;  2ZCS A;  4KQS A;  2AZJ A;  1HM7 A;  3N5J F;  3VJ9 A;  1UBX A;  4RXC A;  3DYF A;  4GAX A;  3VJD A;  3KB9 A;  3WCD A;  2E8U A;  3WE9 A;  4H5D F;  3AQC B;  5AYP A;  5ILH A;  1UBW A;  1ZW5 A;  1V4I A;  4QXS F;  3DYG A;  1KIZ A;  3OAB B;  3KRO A;  5IN8 A;  4NKF A;  4Q23 A;  2E94 A;  3RYE A;  3IPI A;  1N24 A;  1V4E A;  2PS6 A;  3WCM A;  1JFG A;  2F8Z F;  5ER8 A;  3SDR A;  5IMP A;  4KK2 A;  4LFV F;  3ACW A;  5HN9 A;  5DGN F;  3WCG A;  2E8W A;  5IK6 A;  2Z52 A;  4H5E F;  2F8C F;  4DHD A;  2Z78 A;  3LGK A;  1N21 A;  4LLS A;  3P41 A;  3ZCD A;  5A0I A;  2Z4Y A;  4XQT F;  3KRP A;  2ZCO A;  3KRA B;  4LOB A;  4E9Z A;  3Q2Q A;  3WEH A;  5ERN A;  3WEK A;  3LJI A;  3MAV A;  4XQS F;  2ZEU A;  2Z4W A;  4RNQ A;  5IK0 A;  3DYH A;  4KKM A;  3WCF A;  4LZC A;  1WL3 A;  4OKM A;  1HXA A;  2Z4Z A;  4LUU A;  3PDE A;  2E95 A;  4KPJ A;  3N3D A;  2ONH A;  4PVX F;  2Z50 A;  1KIY A;  4LPH F;  4N1Z F;  1WKZ A;  5AHU B;  3ICN A;  1WL2 A;  3S9V A;  1VG6 A;  4EA0 A;  5DGM F;  3WCL A;  5ILI A;  1YHK A;  3ICZ A;  1V4K A; 
#chains in the Genus database with same CATH homology
 2OA6 A;  4P0W A;  3N0G A;  1WMW A;  5JUZ F;  1HM4 A;  4KFA A;  4OGU A;  2Z4V A;  4FP4 A;  3WCA A;  3CP6 A;  3LG5 A;  1WY0 A;  3V66 A;  3ADZ A;  4P0X A;  3WEI A;  5B02 A;  3TFV A;  4JZB A;  4LZ0 A;  4F6X A;  3OYR A;  5E8L A;  2PS5 A;  3W7F A;  3CC9 A;  3V1X A;  1V4H A;  3M0G A;  5ILY A;  5IMN A;  2P1C A;  5HN7 A;  5AEL A;  3G4D A;  3G4F A;  4LPG F;  4LTZ A;  3WJO A;  4LXW A;  4L2X F;  2H8O A;  4UMJ A;  5B00 A;  4EA2 A;  4GP1 A;  2Q9Z A;  3KBK A;  4JYX A;  2E90 A;  3PKO A;  3WCH A;  4KVY A;  2OPN A;  3AE0 A;  1N23 A;  4H5C F;  3SDU A;  1RQJ A;  5ILD A;  3ZMB A;  2E8X A;  4K10 A;  4LA6 A;  3WCJ A;  3LEE A;  3SAE A;  3VJB A;  5B0I A;  3WJN A;  2Q58 A;  5E8H A;  2E8T A;  4E1E A;  5IL3 A;  1YYT A;  3VJ8 A;  2AEK A;  2ONG A;  5I1U A;  1HXG A;  2Q80 A;  2FTZ A;  2OPM A;  1YYU A;  3OAC B;  2AZK A;  3WC9 A;  4GA3 A;  1FPS A;  3RBM A;  4KQ5 A;  3CKE A;  4WK5 A;  3N3L F;  3ICK A;  4DZW A;  2F94 F;  3LLW A;  4XQR F;  4DWB A;  3KRF A;  3VJE A;  2E92 A;  3RMG A;  4NFJ F;  4PVY F;  4LFG A;  5IMI A;  2AET A;  5IKA A;  3N0F A;  2O1O A;  3NPK A;  3Q30 A;  4OMH A;  4LZ3 A;  3WEJ A;  3WEF A;  1VG4 A;  2E91 A;  5ILZ A;  2E8V A;  3N6K F;  2F7M F;  3Q2Z A;  5C05 A;  3OAB A;  3QKC A;  1YJ4 A;  3PH7 A;  2VF6 A;  3P5P A;  3WJK A;  5IL8 A;  1YQ7 A;  4GP2 A;  3KRO B;  5DJV F;  3LZ9 A;  3N1W F;  4KUX A;  4ZQ8 A;  4DXJ A;  1DI1 A;  3PYA A;  2ZCR A;  3LOM A;  5B0L A;  4NG6 A;  3TFP A;  4MC0 A;  5DIQ F;  5B03 A;  3EGT A;  3NF2 A;  2PS7 A;  5E8K A;  3WSB A;  5A0K A;  3ACY A;  2OGD A;  4QPF A;  1YYS A;  3AQB B;  3KRA A;  1DGP A;  1UBV A;  2Z7I A;  4NFK F;  3VJC A;  3WEG A;  4JZX A;  2J1O A;  5IM1 A;  2AZL A;  1JFA A;  3SDV A;  3KRP B;  5DHI A;  3WSA A;  4KPD A;  4HD1 A;  2DH4 A;  2PS4 A;  3NPR A;  3WCI A;  2Z7H A;  1EZF A;  3ICM A;  3M01 A;  3SDT A;  3TFN A;  4RXD A;  4DEM F;  3MZV A;  3V1V A;  3M00 A;  5DJR F;  5CG6 A;  5JV2 F;  4KWD A;  5IK9 A;  1N22 A;  4NUA A;  2EWG A;  3N45 F;  2F92 F;  5JV0 F;  3Q1O A;  3P8L A;  1UBY A;  1YYR A;  5IKH A;  3RYW A;  3LSN A;  4DWG A;  5ILJ A;  5KSX F;  4LLT A;  3SDQ A;  4F62 A;  1YV5 A;  1RTR A;  3P8R A;  4OKZ A;  3ASX A;  1RQI A;  3QQV A;  1VG3 A;  3N46 F;  1VG7 A;  4JVJ F;  2FOR A;  2PS8 A;  4OMG A;  3LGZ B;  3ZOU A;  3UCA A;  3BNY A;  4KVI A;  1YYQ A;  3ID0 A;  5JV1 F;  3KRC A;  5H9D A;  3TC1 A;  2ZCQ A;  3TS7 A;  3B7L A;  3PYB A;  2F9K F;  2I19 A;  5DZ2 A;  1HXC A;  1N20 A;  4NKE A;  3ZMC A;  4KVD A;  3BNX A;  5EAS A;  1PS1 A;  4LA5 A;  2J5C A;  4RYP A;  4F6V A;  4P0V A;  5B0K A;  5JA0 F;  1YHM A;  4DI5 A;  2E93 A;  1WL1 A;  3VJA A;  1VG2 A;  5DGS F;  5DJP F;  4LIX A;  5B0M A;  3N49 F;  3AQ0 A;  3P5R A;  4MC3 A;  5B01 A;  4MC8 A;  2Z4X A;  3S4J A;  5ERM A;  3LDW A;  5ILK A;  3M02 A;  5EAT A;  5B0J A;  2E4O A;  2ZY1 A;  2Q9Y A;  5ERO A;  3EFQ A;  2J1P A;  4N9U A;  5EAU A;  4EA1 A;  3WCE A;  5DW7 A;  3IBA A;  4NFI F;  2ZEV A;  3APZ A;  3LMD A;  3N5H F;  1HX9 A;  4LFE A;  3OAC A;  3M9U A;  5IVG A;  1YHL A;  3LK5 A;  4KQU A;  2QIS A;  5HNA A;  4KVW A;  5HN8 A;  4LTV A;  2RAH A;  5CG5 A;  3WCB A;  5A0J A;  3EZ3 A;  2F89 F;  1WL0 A;  3ACX A;  5AFX A;  4FJQ A;  2AEL A;  1N1Z A;  3N1V F;  1V4J A;  3ZL6 A;  5DHK A;  3WCC A;  4JXY A;  4RXE A;  3KRC B;  4RXA A;  3NRI A;  3KRF B;  4E9U A;  1N1B A;  3LVS A;  4JXN A;  2ZCS A;  4KQS A;  2AZJ A;  1HM7 A;  3N5J F;  3VJ9 A;  1UBX A;  4RXC A;  3DYF A;  4GAX A;  3VJD A;  3KB9 A;  3WCD A;  2E8U A;  3WE9 A;  4H5D F;  3AQC B;  5AYP A;  5ILH A;  1UBW A;  1ZW5 A;  1V4I A;  4QXS F;  3DYG A;  1KIZ A;  3OAB B;  3KRO A;  5IN8 A;  4NKF A;  4Q23 A;  2E94 A;  3RYE A;  3IPI A;  1N24 A;  1V4E A;  2PS6 A;  3WCM A;  1JFG A;  2F8Z F;  5ER8 A;  3SDR A;  5IMP A;  4KK2 A;  4LFV F;  3ACW A;  5HN9 A;  5DGN F;  3WCG A;  2E8W A;  5IK6 A;  2Z52 A;  4H5E F;  2F8C F;  4DHD A;  2Z78 A;  3LGK A;  1N21 A;  4LLS A;  3P41 A;  3ZCD A;  5A0I A;  2Z4Y A;  4XQT F;  3KRP A;  2ZCO A;  3KRA B;  4LOB A;  4E9Z A;  3Q2Q A;  3WEH A;  5ERN A;  3WEK A;  3LJI A;  3MAV A;  4XQS F;  2ZEU A;  2Z4W A;  4RNQ A;  5IK0 A;  3DYH A;  4KKM A;  3WCF A;  4LZC A;  1WL3 A;  4OKM A;  1HXA A;  2Z4Z A;  4LUU A;  3PDE A;  2E95 A;  4KPJ A;  3N3D A;  2ONH A;  4PVX F;  2Z50 A;  1KIY A;  4LPH F;  4N1Z F;  1WKZ A;  5AHU B;  3ICN A;  1WL2 A;  3S9V A;  1VG6 A;  4EA0 A;  5DGM F;  3WCL A;  5ILI A;  1YHK A;  3ICZ A;  1V4K A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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