3LGZB

Crystal structure of dehydrosqualene synthase y129a from s. aureus complexed with presqualene pyrophosphate
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
284
structure length
279
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGACYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of action and inhibition of dehydrosqualene synthase.
pubmed doi rcsb
molecule tags Transferase
source organism Staphylococcus aureus
molecule keywords Dehydrosqualene synthase
total genus 114
structure length 279
sequence length 284
ec nomenclature ec 2.5.1.96: 4,4'-diapophytoene synthase.
pdb deposition date 2010-01-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3lgzB00
2Z4ZA 3EGTA 3LSNA 3WSBA 3Q2QA 4LZ0A 5A0JA 1WL1A 2E8VA 2F8CF 4KUXA 4LFVF 5B00A 1EZFA 4H5CF 1KIYA 1YV5A 4XQRF 3G4FA 3IBAA 3SDUA 3N1VF 5IK0A 5CG6A 5I1UA 3AE0A 2ZEUA 2AELA 4NFKF 3S9VA 3P8RA 4H5EF 2F8ZF 3NRIA 4RXEA 4LIXA 1V4JA 1YQ7A 4ZQ8A 3CC9A 4RXAA 2AZLA 5IL3A 3LK5A 2VF6A 3WCJA 3N45F 4LZ3A 4JVJF 3AQBB 1UBXA 3ACXA 2Z50A 2Z4YA 4E1EA 4LFGA 3Q1OA 3Q30A 2E8XA 3LGZB 4KVDA 4LTZA 4XQSF 1JFGA 3V1VA 2PS5A 2J1PA 2H8OA 3V66A 4LXWA 4L2XF 3SDRA 4DWGA 2ZCSA 3PYBA 3M01A 2AEKA 4WK5A 3ASXA 3TFVA 4DWBA 2E94A 5B01A 4KVWA 3VJDA 4OKZA 1V4HA 4P0XA 4EA0A 4N1ZF 5DZ2A 4EA2A 2OPMA 3KRCA 5DIQF 3RYEA 1RTRA 1HXAA 1N1ZA 3OABB 3LZ9A 4RNQA 4UMJA 4RXCA 2PS6A 4F62A 1N23A 5HN8A 3W7FA 5B0IA 4N9UA 3M02A 4LA6A 3LJIA 4Q23A 2F92F 2E93A 4NFJF 1RQIA 3VJCA 5EASA 1YYSA 5B0MA 4JZBA 2Q58A 3RYWA 4NKEA 1DI1A 2Z4WA 3ACWA 5ILYA 3KRFB 3RMGA 3OACB 5H9DA 3QQVA 2PS7A 3SAEA 1VG4A 3RBMA 4H5DF 1YHMA 2Z4XA 5DJRF 5C05A 3N49F 4KVIA 5ILJA 4K10A 5JV2F 2RAHA 4KK2A 3N1WF 5IKHA 4LLSA 2E90A 1HM4A 3KRPB 3DYGA 3PH7A 1N24A 4MC8A 2Z52A 3WCMA 4NG6A 3DYHA 5JV1F 2Q9YA 3N5JF 5DW7A 3WEIA 3WCAA 2E91A 5EAUA 2PS8A 3G4DA 3M9UA 3WCIA 1WKZA 5IMPA 2ZEVA 4KQ5A 4E9ZA 1DGPA 3LGKA 5B0KA 3LLWA 3OYRA 3LEEA 2ZCQA 3BNYA 3LOMA 3LMDA 4JXNA 1HXGA 3LG5A 5ILHA 5AFXA 3MAVA 4E9UA 5IMIA 1RQJA 3VJEA 4DEMF 5ILIA 3WCFA 3TFNA 3LDWA 1HX9A 3M00A 5IM1A 3ZMBA 3M0GA 4LPHF 3NPRA 3WEHA 2Z4VA 1UBWA 5B0JA 3KRAB 3WCCA 4OKMA 4LPGF 4JYXA 4HD1A 3KBKA 4LTVA 3IPIA 5E8KA 3WCHA 4KPDA 3APZA 4GA3A 1WY0A 5JA0F 1HM7A 3ZCDA 3N5HF 3B7LA 2E95A 3KROB 2F9KF 5B02A 3OABA 4FP4A 3UCAA 3ZL6A 4F6VA 1KIZA 5AELA 1V4IA 5CG5A 3ADZA 3WCBA 1WL3A 3QKCA 3VJAA 5JV0F 1YHKA 3WEKA 3WC9A 2OGDA 2AZJA 3SDQA 4LFEA 2F7MF 3WCLA 4GP1A 1N1BA 1JFAA 5DGMF 5DGSF 4DI5A 1N21A 3Q2ZA 3ZOUA 3N0GA 4RXDA 3WCDA 1VG3A 3WJNA 2Q9ZA 3TS7A 4JZXA 3PDEA 3AQCB 1V4KA 3PYAA 4JXYA 5HN7A 4P0WA 3WJKA 1FPSA 3N3DA 2FTZA 3N3LF 3WCGA 4LLTA 5KSXF 1PS1A 1N20A 4QXSF 4KPJA 4NFIF 3WJOA 4FJQA 5IVGA 3PKOA 3MZVA 4PVXF 2EWGA 2AZKA 1YYRA 1VG2A 5EATA 5E8HA 2J1OA 3VJ9A 4GP2A 2OPNA 4XQTF 1V4EA 1YYUA 3CKEA 2I19A 5IK9A 5B0LA 2AETA 2FORA 3ICZA 2Z78A 4LUUA 5ER8A 5B03A 5ERMA 2ZY1A 4OGUA 5EROA 4KQSA 2OA6A 4KQUA 4NUAA 3VJBA 3P41A 5IK6A 5E8LA 3WE9A 4KFAA 4P0VA 1HXCA 3KRAA 2J5CA 2ONGA 1YJ4A 5AHUB 3WEFA 2P1CA 2E8WA 5IN8A 3ACYA 4OMGA 5DHKA 3ZMCA 2Z7HA 3WSAA 3ICNA 4QPFA 3P5RA 5IKAA 3AQ0A 4DXJA 4KWDA 3TC1A 2F89F 2PS4A 3ICKA 3SDVA 3N0FA 4F6XA 3LVSA 3N6KF 3KB9A 5AYPA 5ILDA 1VG6A 2Q80A 3EFQA 1WL0A 3KROA 2E4OA 2E8TA 3DYFA 1UBYA 5IMNA 5JUZF 3EZ3A 5HN9A 3V1XA 4LOBA 3NF2A 3CP6A 5DHIA 3WEGA 5ILZA 5DJPF 1WL2A 5A0IA 2QISA 3TFPA 4EA1A 4LZCA 1YYTA 2F94F 5A0KA 1VG7A 4KVYA 2DH4A 4MC3A 1N22A 3BNXA 4GAXA 2ZCOA 4LA5A 2Z7IA 3WEJA 5DJVF 2E92A 3P5PA 3WCEA 4NKFA 3KRCB 3KRFA 3OACA 4OMHA 3NPKA 3ID0A 4DZWA 2E8UA 5ERNA 4KKMA 4PVYF 5HNAA 1YHLA 3N46F 2ONHA 1YYQA 3S4JA 3ICMA 3P8LA 4MC0A 3VJ8A 5IL8A 3KRPA 1WMWA 2O1OA 1UBVA 1ZW5A 4DHDA 4RYPA 5ILKA 2ZCRA 5DGNF 3SDTA
chains in the Genus database with same CATH superfamily
2Z4ZA 3EGTA 3LSNA 3WSBA 3Q2QA 4LZ0A 5A0JA 1WL1A 2E8VA 2F8CF 4KUXA 4LFVF 5B00A 1EZFA 4H5CF 1KIYA 1YV5A 4XQRF 3G4FA 3IBAA 3SDUA 3N1VF 5IK0A 5CG6A 5I1UA 3AE0A 2ZEUA 2AELA 4NFKF 3S9VA 3P8RA 4H5EF 2F8ZF 3NRIA 4RXEA 4LIXA 1V4JA 1YQ7A 4ZQ8A 3CC9A 4RXAA 2AZLA 5IL3A 3LK5A 2VF6A 3WCJA 3N45F 4LZ3A 4JVJF 3AQBB 1UBXA 3ACXA 2Z50A 2Z4YA 4E1EA 4LFGA 3Q1OA 3Q30A 2E8XA 3LGZB 4KVDA 4LTZA 4XQSF 1JFGA 3V1VA 2PS5A 2J1PA 2H8OA 3V66A 4LXWA 4L2XF 3SDRA 4DWGA 2ZCSA 3PYBA 3M01A 2AEKA 4WK5A 3ASXA 3TFVA 4DWBA 2E94A 5B01A 4KVWA 3VJDA 4OKZA 1V4HA 4P0XA 4EA0A 4N1ZF 5DZ2A 4EA2A 2OPMA 3KRCA 5DIQF 3RYEA 1RTRA 1HXAA 1N1ZA 3OABB 3LZ9A 4RNQA 4UMJA 4RXCA 2PS6A 4F62A 1N23A 5HN8A 3W7FA 5B0IA 4N9UA 3M02A 4LA6A 3LJIA 4Q23A 2F92F 2E93A 4NFJF 1RQIA 3VJCA 5EASA 1YYSA 5B0MA 4JZBA 2Q58A 3RYWA 4NKEA 1DI1A 2Z4WA 3ACWA 5ILYA 3KRFB 3RMGA 3OACB 5H9DA 3QQVA 2PS7A 3SAEA 1VG4A 3RBMA 4H5DF 1YHMA 2Z4XA 5DJRF 5C05A 3N49F 4KVIA 5ILJA 4K10A 5JV2F 2RAHA 4KK2A 3N1WF 5IKHA 4LLSA 2E90A 1HM4A 3KRPB 3DYGA 3PH7A 1N24A 4MC8A 2Z52A 3WCMA 4NG6A 3DYHA 5JV1F 2Q9YA 3N5JF 5DW7A 3WEIA 3WCAA 2E91A 5EAUA 2PS8A 3G4DA 3M9UA 3WCIA 1WKZA 5IMPA 2ZEVA 4KQ5A 4E9ZA 1DGPA 3LGKA 5B0KA 3LLWA 3OYRA 3LEEA 2ZCQA 3BNYA 3LOMA 3LMDA 4JXNA 1HXGA 3LG5A 5ILHA 5AFXA 3MAVA 4E9UA 5IMIA 1RQJA 3VJEA 4DEMF 5ILIA 3WCFA 3TFNA 3LDWA 1HX9A 3M00A 5IM1A 3ZMBA 3M0GA 4LPHF 3NPRA 3WEHA 2Z4VA 1UBWA 5B0JA 3KRAB 3WCCA 4OKMA 4LPGF 4JYXA 4HD1A 3KBKA 4LTVA 3IPIA 5E8KA 3WCHA 4KPDA 3APZA 4GA3A 1WY0A 5JA0F 1HM7A 3ZCDA 3N5HF 3B7LA 2E95A 3KROB 2F9KF 5B02A 3OABA 4FP4A 3UCAA 3ZL6A 4F6VA 1KIZA 5AELA 1V4IA 5CG5A 3ADZA 3WCBA 1WL3A 3QKCA 3VJAA 5JV0F 1YHKA 3WEKA 3WC9A 2OGDA 2AZJA 3SDQA 4LFEA 2F7MF 3WCLA 4GP1A 1N1BA 1JFAA 5DGMF 5DGSF 4DI5A 1N21A 3Q2ZA 3ZOUA 3N0GA 4RXDA 3WCDA 1VG3A 3WJNA 2Q9ZA 3TS7A 4JZXA 3PDEA 3AQCB 1V4KA 3PYAA 4JXYA 5HN7A 4P0WA 3WJKA 1FPSA 3N3DA 2FTZA 3N3LF 3WCGA 4LLTA 5KSXF 1PS1A 1N20A 4QXSF 4KPJA 4NFIF 3WJOA 4FJQA 5IVGA 3PKOA 3MZVA 4PVXF 2EWGA 2AZKA 1YYRA 1VG2A 5EATA 5E8HA 2J1OA 3VJ9A 4GP2A 2OPNA 4XQTF 1V4EA 1YYUA 3CKEA 2I19A 5IK9A 5B0LA 2AETA 2FORA 3ICZA 2Z78A 4LUUA 5ER8A 5B03A 5ERMA 2ZY1A 4OGUA 5EROA 4KQSA 2OA6A 4KQUA 4NUAA 3VJBA 3P41A 5IK6A 5E8LA 3WE9A 4KFAA 4P0VA 1HXCA 3KRAA 2J5CA 2ONGA 1YJ4A 5AHUB 3WEFA 2P1CA 2E8WA 5IN8A 3ACYA 4OMGA 5DHKA 3ZMCA 2Z7HA 3WSAA 3ICNA 4QPFA 3P5RA 5IKAA 3AQ0A 4DXJA 4KWDA 3TC1A 2F89F 2PS4A 3ICKA 3SDVA 3N0FA 4F6XA 3LVSA 3N6KF 3KB9A 5AYPA 5ILDA 1VG6A 2Q80A 3EFQA 1WL0A 3KROA 2E4OA 2E8TA 3DYFA 1UBYA 5IMNA 5JUZF 3EZ3A 5HN9A 3V1XA 4LOBA 3NF2A 3CP6A 5DHIA 3WEGA 5ILZA 5DJPF 1WL2A 5A0IA 2QISA 3TFPA 4EA1A 4LZCA 1YYTA 2F94F 5A0KA 1VG7A 4KVYA 2DH4A 4MC3A 1N22A 3BNXA 4GAXA 2ZCOA 4LA5A 2Z7IA 3WEJA 5DJVF 2E92A 3P5PA 3WCEA 4NKFA 3KRCB 3KRFA 3OACA 4OMHA 3NPKA 3ID0A 4DZWA 2E8UA 5ERNA 4KKMA 4PVYF 5HNAA 1YHLA 3N46F 2ONHA 1YYQA 3S4JA 3ICMA 3P8LA 4MC0A 3VJ8A 5IL8A 3KRPA 1WMWA 2O1OA 1UBVA 1ZW5A 4DHDA 4RYPA 5ILKA 2ZCRA 5DGNF 3SDTA
chains in the Genus database with same CATH topology
2Z4ZA 3EGTA 3LSNA 3WSBA 3Q2QA 4LZ0A 5A0JA 1WL1A 2E8VA 2F8CF 4KUXA 4LFVF 5B00A 1EZFA 4H5CF 1KIYA 1YV5A 4XQRF 3G4FA 3IBAA 3SDUA 3N1VF 5IK0A 5CG6A 5I1UA 3AE0A 2ZEUA 2AELA 4NFKF 3S9VA 3P8RA 4H5EF 2F8ZF 3NRIA 4RXEA 4LIXA 1V4JA 1YQ7A 4ZQ8A 3CC9A 4RXAA 2AZLA 5IL3A 3LK5A 2VF6A 3WCJA 3N45F 4LZ3A 4JVJF 3AQBB 1UBXA 3ACXA 2Z50A 2Z4YA 4E1EA 4LFGA 3Q1OA 3Q30A 2E8XA 3LGZB 4KVDA 4LTZA 4XQSF 1JFGA 3V1VA 2PS5A 2J1PA 2H8OA 3V66A 4LXWA 4L2XF 3SDRA 4DWGA 2ZCSA 3PYBA 3M01A 2AEKA 4WK5A 3ASXA 3TFVA 4DWBA 2E94A 5B01A 4KVWA 3VJDA 4OKZA 1V4HA 4P0XA 4EA0A 4N1ZF 5DZ2A 4EA2A 2OPMA 3KRCA 5DIQF 3RYEA 1RTRA 1HXAA 1N1ZA 3OABB 3LZ9A 4RNQA 4UMJA 4RXCA 2PS6A 4F62A 1N23A 5HN8A 3W7FA 5B0IA 4N9UA 3M02A 4LA6A 3LJIA 4Q23A 2F92F 2E93A 4NFJF 1RQIA 3VJCA 5EASA 1YYSA 5B0MA 4JZBA 2Q58A 3RYWA 4NKEA 1DI1A 2Z4WA 3ACWA 5ILYA 3KRFB 3RMGA 3OACB 5H9DA 3QQVA 2PS7A 3SAEA 1VG4A 3RBMA 4H5DF 1YHMA 2Z4XA 5DJRF 5C05A 3N49F 4KVIA 5ILJA 4K10A 5JV2F 2RAHA 4KK2A 3N1WF 5IKHA 4LLSA 2E90A 1HM4A 3KRPB 3DYGA 3PH7A 1N24A 4MC8A 2Z52A 3WCMA 4NG6A 3DYHA 5JV1F 2Q9YA 3N5JF 5DW7A 3WEIA 3WCAA 2E91A 5EAUA 2PS8A 3G4DA 3M9UA 3WCIA 1WKZA 5IMPA 2ZEVA 4KQ5A 4E9ZA 1DGPA 3LGKA 5B0KA 3LLWA 3OYRA 3LEEA 2ZCQA 3BNYA 3LOMA 3LMDA 4JXNA 1HXGA 3LG5A 5ILHA 5AFXA 3MAVA 4E9UA 5IMIA 1RQJA 3VJEA 4DEMF 5ILIA 3WCFA 3TFNA 3LDWA 1HX9A 3M00A 5IM1A 3ZMBA 3M0GA 4LPHF 3NPRA 3WEHA 2Z4VA 1UBWA 5B0JA 3KRAB 3WCCA 4OKMA 4LPGF 4JYXA 4HD1A 3KBKA 4LTVA 3IPIA 5E8KA 3WCHA 4KPDA 3APZA 4GA3A 1WY0A 5JA0F 1HM7A 3ZCDA 3N5HF 3B7LA 2E95A 3KROB 2F9KF 5B02A 3OABA 4FP4A 3UCAA 3ZL6A 4F6VA 1KIZA 5AELA 1V4IA 5CG5A 3ADZA 3WCBA 1WL3A 3QKCA 3VJAA 5JV0F 1YHKA 3WEKA 3WC9A 2OGDA 2AZJA 3SDQA 4LFEA 2F7MF 3WCLA 4GP1A 1N1BA 1JFAA 5DGMF 5DGSF 4DI5A 1N21A 3Q2ZA 3ZOUA 3N0GA 4RXDA 3WCDA 1VG3A 3WJNA 2Q9ZA 3TS7A 4JZXA 3PDEA 3AQCB 1V4KA 3PYAA 4JXYA 5HN7A 4P0WA 3WJKA 1FPSA 3N3DA 2FTZA 3N3LF 3WCGA 4LLTA 5KSXF 1PS1A 1N20A 4QXSF 4KPJA 4NFIF 3WJOA 4FJQA 5IVGA 3PKOA 3MZVA 4PVXF 2EWGA 2AZKA 1YYRA 1VG2A 5EATA 5E8HA 2J1OA 3VJ9A 4GP2A 2OPNA 4XQTF 1V4EA 1YYUA 3CKEA 2I19A 5IK9A 5B0LA 2AETA 2FORA 3ICZA 2Z78A 4LUUA 5ER8A 5B03A 5ERMA 2ZY1A 4OGUA 5EROA 4KQSA 2OA6A 4KQUA 4NUAA 3VJBA 3P41A 5IK6A 5E8LA 3WE9A 4KFAA 4P0VA 1HXCA 3KRAA 2J5CA 2ONGA 1YJ4A 5AHUB 3WEFA 2P1CA 2E8WA 5IN8A 3ACYA 4OMGA 5DHKA 3ZMCA 2Z7HA 3WSAA 3ICNA 4QPFA 3P5RA 5IKAA 3AQ0A 4DXJA 4KWDA 3TC1A 2F89F 2PS4A 3ICKA 3SDVA 3N0FA 4F6XA 3LVSA 3N6KF 3KB9A 5AYPA 5ILDA 1VG6A 2Q80A 3EFQA 1WL0A 3KROA 2E4OA 2E8TA 3DYFA 1UBYA 5IMNA 5JUZF 3EZ3A 5HN9A 3V1XA 4LOBA 3NF2A 3CP6A 5DHIA 3WEGA 5ILZA 5DJPF 1WL2A 5A0IA 2QISA 3TFPA 4EA1A 4LZCA 1YYTA 2F94F 5A0KA 1VG7A 4KVYA 2DH4A 4MC3A 1N22A 3BNXA 4GAXA 2ZCOA 4LA5A 2Z7IA 3WEJA 5DJVF 2E92A 3P5PA 3WCEA 4NKFA 3KRCB 3KRFA 3OACA 4OMHA 3NPKA 3ID0A 4DZWA 2E8UA 5ERNA 4KKMA 4PVYF 5HNAA 1YHLA 3N46F 2ONHA 1YYQA 3S4JA 3ICMA 3P8LA 4MC0A 3VJ8A 5IL8A 3KRPA 1WMWA 2O1OA 1UBVA 1ZW5A 4DHDA 4RYPA 5ILKA 2ZCRA 5DGNF 3SDTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z4Z A;  3EGT A;  3LSN A;  3WSB A;  3Q2Q A;  4LZ0 A;  5A0J A;  1WL1 A;  2E8V A;  2F8C F;  4KUX A;  4LFV F;  5B00 A;  1EZF A;  4H5C F;  1KIY A;  1YV5 A;  4XQR F;  3G4F A;  3IBA A;  3SDU A;  3N1V F;  5IK0 A;  5CG6 A;  5I1U A;  3AE0 A;  2ZEU A;  2AEL A;  4NFK F;  3S9V A;  3P8R A;  4H5E F;  2F8Z F;  3NRI A;  4RXE A;  4LIX A;  1V4J A;  1YQ7 A;  4ZQ8 A;  3CC9 A;  4RXA A;  2AZL A;  5IL3 A;  3LK5 A;  2VF6 A;  3WCJ A;  3N45 F;  4LZ3 A;  4JVJ F;  3AQB B;  1UBX A;  3ACX A;  2Z50 A;  2Z4Y A;  4E1E A;  4LFG A;  3Q1O A;  3Q30 A;  2E8X A;  3LGZ B;  4KVD A;  4LTZ A;  4XQS F;  1JFG A;  3V1V A;  2PS5 A;  2J1P A;  2H8O A;  3V66 A;  4LXW A;  4L2X F;  3SDR A;  4DWG A;  2ZCS A;  3PYB A;  3M01 A;  2AEK A;  4WK5 A;  3ASX A;  3TFV A;  4DWB A;  2E94 A;  5B01 A;  4KVW A;  3VJD A;  4OKZ A;  1V4H A;  4P0X A;  4EA0 A;  4N1Z F;  5DZ2 A;  4EA2 A;  2OPM A;  3KRC A;  5DIQ F;  3RYE A;  1RTR A;  1HXA A;  1N1Z A;  3OAB B;  3LZ9 A;  4RNQ A;  4UMJ A;  4RXC A;  2PS6 A;  4F62 A;  1N23 A;  5HN8 A;  3W7F A;  5B0I A;  4N9U A;  3M02 A;  4LA6 A;  3LJI A;  4Q23 A;  2F92 F;  2E93 A;  4NFJ F;  1RQI A;  3VJC A;  5EAS A;  1YYS A;  5B0M A;  4JZB A;  2Q58 A;  3RYW A;  4NKE A;  1DI1 A;  2Z4W A;  3ACW A;  5ILY A;  3KRF B;  3RMG A;  3OAC B;  5H9D A;  3QQV A;  2PS7 A;  3SAE A;  1VG4 A;  3RBM A;  4H5D F;  1YHM A;  2Z4X A;  5DJR F;  5C05 A;  3N49 F;  4KVI A;  5ILJ A;  4K10 A;  5JV2 F;  2RAH A;  4KK2 A;  3N1W F;  5IKH A;  4LLS A;  2E90 A;  1HM4 A;  3KRP B;  3DYG A;  3PH7 A;  1N24 A;  4MC8 A;  2Z52 A;  3WCM A;  4NG6 A;  3DYH A;  5JV1 F;  2Q9Y A;  3N5J F;  5DW7 A;  3WEI A;  3WCA A;  2E91 A;  5EAU A;  2PS8 A;  3G4D A;  3M9U A;  3WCI A;  1WKZ A;  5IMP A;  2ZEV A;  4KQ5 A;  4E9Z A;  1DGP A;  3LGK A;  5B0K A;  3LLW A;  3OYR A;  3LEE A;  2ZCQ A;  3BNY A;  3LOM A;  3LMD A;  4JXN A;  1HXG A;  3LG5 A;  5ILH A;  5AFX A;  3MAV A;  4E9U A;  5IMI A;  1RQJ A;  3VJE A;  4DEM F;  5ILI A;  3WCF A;  3TFN A;  3LDW A;  1HX9 A;  3M00 A;  5IM1 A;  3ZMB A;  3M0G A;  4LPH F;  3NPR A;  3WEH A;  2Z4V A;  1UBW A;  5B0J A;  3KRA B;  3WCC A;  4OKM A;  4LPG F;  4JYX A;  4HD1 A;  3KBK A;  4LTV A;  3IPI A;  5E8K A;  3WCH A;  4KPD A;  3APZ A;  4GA3 A;  1WY0 A;  5JA0 F;  1HM7 A;  3ZCD A;  3N5H F;  3B7L A;  2E95 A;  3KRO B;  2F9K F;  5B02 A;  3OAB A;  4FP4 A;  3UCA A;  3ZL6 A;  4F6V A;  1KIZ A;  5AEL A;  1V4I A;  5CG5 A;  3ADZ A;  3WCB A;  1WL3 A;  3QKC A;  3VJA A;  5JV0 F;  1YHK A;  3WEK A;  3WC9 A;  2OGD A;  2AZJ A;  3SDQ A;  4LFE A;  2F7M F;  3WCL A;  4GP1 A;  1N1B A;  1JFA A;  5DGM F;  5DGS F;  4DI5 A;  1N21 A;  3Q2Z A;  3ZOU A;  3N0G A;  4RXD A;  3WCD A;  1VG3 A;  3WJN A;  2Q9Z A;  3TS7 A;  4JZX A;  3PDE A;  3AQC B;  1V4K A;  3PYA A;  4JXY A;  5HN7 A;  4P0W A;  3WJK A;  1FPS A;  3N3D A;  2FTZ A;  3N3L F;  3WCG A;  4LLT A;  5KSX F;  1PS1 A;  1N20 A;  4QXS F;  4KPJ A;  4NFI F;  3WJO A;  4FJQ A;  5IVG A;  3PKO A;  3MZV A;  4PVX F;  2EWG A;  2AZK A;  1YYR A;  1VG2 A;  5EAT A;  5E8H A;  2J1O A;  3VJ9 A;  4GP2 A;  2OPN A;  4XQT F;  1V4E A;  1YYU A;  3CKE A;  2I19 A;  5IK9 A;  5B0L A;  2AET A;  2FOR A;  3ICZ A;  2Z78 A;  4LUU A;  5ER8 A;  5B03 A;  5ERM A;  2ZY1 A;  4OGU A;  5ERO A;  4KQS A;  2OA6 A;  4KQU A;  4NUA A;  3VJB A;  3P41 A;  5IK6 A;  5E8L A;  3WE9 A;  4KFA A;  4P0V A;  1HXC A;  3KRA A;  2J5C A;  2ONG A;  1YJ4 A;  5AHU B;  3WEF A;  2P1C A;  2E8W A;  5IN8 A;  3ACY A;  4OMG A;  5DHK A;  3ZMC A;  2Z7H A;  3WSA A;  3ICN A;  4QPF A;  3P5R A;  5IKA A;  3AQ0 A;  4DXJ A;  4KWD A;  3TC1 A;  2F89 F;  2PS4 A;  3ICK A;  3SDV A;  3N0F A;  4F6X A;  3LVS A;  3N6K F;  3KB9 A;  5AYP A;  5ILD A;  1VG6 A;  2Q80 A;  3EFQ A;  1WL0 A;  3KRO A;  2E4O A;  2E8T A;  3DYF A;  1UBY A;  5IMN A;  5JUZ F;  3EZ3 A;  5HN9 A;  3V1X A;  4LOB A;  3NF2 A;  3CP6 A;  5DHI A;  3WEG A;  5ILZ A;  5DJP F;  1WL2 A;  5A0I A;  2QIS A;  3TFP A;  4EA1 A;  4LZC A;  1YYT A;  2F94 F;  5A0K A;  1VG7 A;  4KVY A;  2DH4 A;  4MC3 A;  1N22 A;  3BNX A;  4GAX A;  2ZCO A;  4LA5 A;  2Z7I A;  3WEJ A;  5DJV F;  2E92 A;  3P5P A;  3WCE A;  4NKF A;  3KRC B;  3KRF A;  3OAC A;  4OMH A;  3NPK A;  3ID0 A;  4DZW A;  2E8U A;  5ERN A;  4KKM A;  4PVY F;  5HNA A;  1YHL A;  3N46 F;  2ONH A;  1YYQ A;  3S4J A;  3ICM A;  3P8L A;  4MC0 A;  3VJ8 A;  5IL8 A;  3KRP A;  1WMW A;  2O1O A;  1UBV A;  1ZW5 A;  4DHD A;  4RYP A;  5ILK A;  2ZCR A;  5DGN F;  3SDT A; 
#chains in the Genus database with same CATH topology
 2Z4Z A;  3EGT A;  3LSN A;  3WSB A;  3Q2Q A;  4LZ0 A;  5A0J A;  1WL1 A;  2E8V A;  2F8C F;  4KUX A;  4LFV F;  5B00 A;  1EZF A;  4H5C F;  1KIY A;  1YV5 A;  4XQR F;  3G4F A;  3IBA A;  3SDU A;  3N1V F;  5IK0 A;  5CG6 A;  5I1U A;  3AE0 A;  2ZEU A;  2AEL A;  4NFK F;  3S9V A;  3P8R A;  4H5E F;  2F8Z F;  3NRI A;  4RXE A;  4LIX A;  1V4J A;  1YQ7 A;  4ZQ8 A;  3CC9 A;  4RXA A;  2AZL A;  5IL3 A;  3LK5 A;  2VF6 A;  3WCJ A;  3N45 F;  4LZ3 A;  4JVJ F;  3AQB B;  1UBX A;  3ACX A;  2Z50 A;  2Z4Y A;  4E1E A;  4LFG A;  3Q1O A;  3Q30 A;  2E8X A;  3LGZ B;  4KVD A;  4LTZ A;  4XQS F;  1JFG A;  3V1V A;  2PS5 A;  2J1P A;  2H8O A;  3V66 A;  4LXW A;  4L2X F;  3SDR A;  4DWG A;  2ZCS A;  3PYB A;  3M01 A;  2AEK A;  4WK5 A;  3ASX A;  3TFV A;  4DWB A;  2E94 A;  5B01 A;  4KVW A;  3VJD A;  4OKZ A;  1V4H A;  4P0X A;  4EA0 A;  4N1Z F;  5DZ2 A;  4EA2 A;  2OPM A;  3KRC A;  5DIQ F;  3RYE A;  1RTR A;  1HXA A;  1N1Z A;  3OAB B;  3LZ9 A;  4RNQ A;  4UMJ A;  4RXC A;  2PS6 A;  4F62 A;  1N23 A;  5HN8 A;  3W7F A;  5B0I A;  4N9U A;  3M02 A;  4LA6 A;  3LJI A;  4Q23 A;  2F92 F;  2E93 A;  4NFJ F;  1RQI A;  3VJC A;  5EAS A;  1YYS A;  5B0M A;  4JZB A;  2Q58 A;  3RYW A;  4NKE A;  1DI1 A;  2Z4W A;  3ACW A;  5ILY A;  3KRF B;  3RMG A;  3OAC B;  5H9D A;  3QQV A;  2PS7 A;  3SAE A;  1VG4 A;  3RBM A;  4H5D F;  1YHM A;  2Z4X A;  5DJR F;  5C05 A;  3N49 F;  4KVI A;  5ILJ A;  4K10 A;  5JV2 F;  2RAH A;  4KK2 A;  3N1W F;  5IKH A;  4LLS A;  2E90 A;  1HM4 A;  3KRP B;  3DYG A;  3PH7 A;  1N24 A;  4MC8 A;  2Z52 A;  3WCM A;  4NG6 A;  3DYH A;  5JV1 F;  2Q9Y A;  3N5J F;  5DW7 A;  3WEI A;  3WCA A;  2E91 A;  5EAU A;  2PS8 A;  3G4D A;  3M9U A;  3WCI A;  1WKZ A;  5IMP A;  2ZEV A;  4KQ5 A;  4E9Z A;  1DGP A;  3LGK A;  5B0K A;  3LLW A;  3OYR A;  3LEE A;  2ZCQ A;  3BNY A;  3LOM A;  3LMD A;  4JXN A;  1HXG A;  3LG5 A;  5ILH A;  5AFX A;  3MAV A;  4E9U A;  5IMI A;  1RQJ A;  3VJE A;  4DEM F;  5ILI A;  3WCF A;  3TFN A;  3LDW A;  1HX9 A;  3M00 A;  5IM1 A;  3ZMB A;  3M0G A;  4LPH F;  3NPR A;  3WEH A;  2Z4V A;  1UBW A;  5B0J A;  3KRA B;  3WCC A;  4OKM A;  4LPG F;  4JYX A;  4HD1 A;  3KBK A;  4LTV A;  3IPI A;  5E8K A;  3WCH A;  4KPD A;  3APZ A;  4GA3 A;  1WY0 A;  5JA0 F;  1HM7 A;  3ZCD A;  3N5H F;  3B7L A;  2E95 A;  3KRO B;  2F9K F;  5B02 A;  3OAB A;  4FP4 A;  3UCA A;  3ZL6 A;  4F6V A;  1KIZ A;  5AEL A;  1V4I A;  5CG5 A;  3ADZ A;  3WCB A;  1WL3 A;  3QKC A;  3VJA A;  5JV0 F;  1YHK A;  3WEK A;  3WC9 A;  2OGD A;  2AZJ A;  3SDQ A;  4LFE A;  2F7M F;  3WCL A;  4GP1 A;  1N1B A;  1JFA A;  5DGM F;  5DGS F;  4DI5 A;  1N21 A;  3Q2Z A;  3ZOU A;  3N0G A;  4RXD A;  3WCD A;  1VG3 A;  3WJN A;  2Q9Z A;  3TS7 A;  4JZX A;  3PDE A;  3AQC B;  1V4K A;  3PYA A;  4JXY A;  5HN7 A;  4P0W A;  3WJK A;  1FPS A;  3N3D A;  2FTZ A;  3N3L F;  3WCG A;  4LLT A;  5KSX F;  1PS1 A;  1N20 A;  4QXS F;  4KPJ A;  4NFI F;  3WJO A;  4FJQ A;  5IVG A;  3PKO A;  3MZV A;  4PVX F;  2EWG A;  2AZK A;  1YYR A;  1VG2 A;  5EAT A;  5E8H A;  2J1O A;  3VJ9 A;  4GP2 A;  2OPN A;  4XQT F;  1V4E A;  1YYU A;  3CKE A;  2I19 A;  5IK9 A;  5B0L A;  2AET A;  2FOR A;  3ICZ A;  2Z78 A;  4LUU A;  5ER8 A;  5B03 A;  5ERM A;  2ZY1 A;  4OGU A;  5ERO A;  4KQS A;  2OA6 A;  4KQU A;  4NUA A;  3VJB A;  3P41 A;  5IK6 A;  5E8L A;  3WE9 A;  4KFA A;  4P0V A;  1HXC A;  3KRA A;  2J5C A;  2ONG A;  1YJ4 A;  5AHU B;  3WEF A;  2P1C A;  2E8W A;  5IN8 A;  3ACY A;  4OMG A;  5DHK A;  3ZMC A;  2Z7H A;  3WSA A;  3ICN A;  4QPF A;  3P5R A;  5IKA A;  3AQ0 A;  4DXJ A;  4KWD A;  3TC1 A;  2F89 F;  2PS4 A;  3ICK A;  3SDV A;  3N0F A;  4F6X A;  3LVS A;  3N6K F;  3KB9 A;  5AYP A;  5ILD A;  1VG6 A;  2Q80 A;  3EFQ A;  1WL0 A;  3KRO A;  2E4O A;  2E8T A;  3DYF A;  1UBY A;  5IMN A;  5JUZ F;  3EZ3 A;  5HN9 A;  3V1X A;  4LOB A;  3NF2 A;  3CP6 A;  5DHI A;  3WEG A;  5ILZ A;  5DJP F;  1WL2 A;  5A0I A;  2QIS A;  3TFP A;  4EA1 A;  4LZC A;  1YYT A;  2F94 F;  5A0K A;  1VG7 A;  4KVY A;  2DH4 A;  4MC3 A;  1N22 A;  3BNX A;  4GAX A;  2ZCO A;  4LA5 A;  2Z7I A;  3WEJ A;  5DJV F;  2E92 A;  3P5P A;  3WCE A;  4NKF A;  3KRC B;  3KRF A;  3OAC A;  4OMH A;  3NPK A;  3ID0 A;  4DZW A;  2E8U A;  5ERN A;  4KKM A;  4PVY F;  5HNA A;  1YHL A;  3N46 F;  2ONH A;  1YYQ A;  3S4J A;  3ICM A;  3P8L A;  4MC0 A;  3VJ8 A;  5IL8 A;  3KRP A;  1WMW A;  2O1O A;  1UBV A;  1ZW5 A;  4DHD A;  4RYP A;  5ILK A;  2ZCR A;  5DGN F;  3SDT A; 
#chains in the Genus database with same CATH homology
 2Z4Z A;  3EGT A;  3LSN A;  3WSB A;  3Q2Q A;  4LZ0 A;  5A0J A;  1WL1 A;  2E8V A;  2F8C F;  4KUX A;  4LFV F;  5B00 A;  1EZF A;  4H5C F;  1KIY A;  1YV5 A;  4XQR F;  3G4F A;  3IBA A;  3SDU A;  3N1V F;  5IK0 A;  5CG6 A;  5I1U A;  3AE0 A;  2ZEU A;  2AEL A;  4NFK F;  3S9V A;  3P8R A;  4H5E F;  2F8Z F;  3NRI A;  4RXE A;  4LIX A;  1V4J A;  1YQ7 A;  4ZQ8 A;  3CC9 A;  4RXA A;  2AZL A;  5IL3 A;  3LK5 A;  2VF6 A;  3WCJ A;  3N45 F;  4LZ3 A;  4JVJ F;  3AQB B;  1UBX A;  3ACX A;  2Z50 A;  2Z4Y A;  4E1E A;  4LFG A;  3Q1O A;  3Q30 A;  2E8X A;  3LGZ B;  4KVD A;  4LTZ A;  4XQS F;  1JFG A;  3V1V A;  2PS5 A;  2J1P A;  2H8O A;  3V66 A;  4LXW A;  4L2X F;  3SDR A;  4DWG A;  2ZCS A;  3PYB A;  3M01 A;  2AEK A;  4WK5 A;  3ASX A;  3TFV A;  4DWB A;  2E94 A;  5B01 A;  4KVW A;  3VJD A;  4OKZ A;  1V4H A;  4P0X A;  4EA0 A;  4N1Z F;  5DZ2 A;  4EA2 A;  2OPM A;  3KRC A;  5DIQ F;  3RYE A;  1RTR A;  1HXA A;  1N1Z A;  3OAB B;  3LZ9 A;  4RNQ A;  4UMJ A;  4RXC A;  2PS6 A;  4F62 A;  1N23 A;  5HN8 A;  3W7F A;  5B0I A;  4N9U A;  3M02 A;  4LA6 A;  3LJI A;  4Q23 A;  2F92 F;  2E93 A;  4NFJ F;  1RQI A;  3VJC A;  5EAS A;  1YYS A;  5B0M A;  4JZB A;  2Q58 A;  3RYW A;  4NKE A;  1DI1 A;  2Z4W A;  3ACW A;  5ILY A;  3KRF B;  3RMG A;  3OAC B;  5H9D A;  3QQV A;  2PS7 A;  3SAE A;  1VG4 A;  3RBM A;  4H5D F;  1YHM A;  2Z4X A;  5DJR F;  5C05 A;  3N49 F;  4KVI A;  5ILJ A;  4K10 A;  5JV2 F;  2RAH A;  4KK2 A;  3N1W F;  5IKH A;  4LLS A;  2E90 A;  1HM4 A;  3KRP B;  3DYG A;  3PH7 A;  1N24 A;  4MC8 A;  2Z52 A;  3WCM A;  4NG6 A;  3DYH A;  5JV1 F;  2Q9Y A;  3N5J F;  5DW7 A;  3WEI A;  3WCA A;  2E91 A;  5EAU A;  2PS8 A;  3G4D A;  3M9U A;  3WCI A;  1WKZ A;  5IMP A;  2ZEV A;  4KQ5 A;  4E9Z A;  1DGP A;  3LGK A;  5B0K A;  3LLW A;  3OYR A;  3LEE A;  2ZCQ A;  3BNY A;  3LOM A;  3LMD A;  4JXN A;  1HXG A;  3LG5 A;  5ILH A;  5AFX A;  3MAV A;  4E9U A;  5IMI A;  1RQJ A;  3VJE A;  4DEM F;  5ILI A;  3WCF A;  3TFN A;  3LDW A;  1HX9 A;  3M00 A;  5IM1 A;  3ZMB A;  3M0G A;  4LPH F;  3NPR A;  3WEH A;  2Z4V A;  1UBW A;  5B0J A;  3KRA B;  3WCC A;  4OKM A;  4LPG F;  4JYX A;  4HD1 A;  3KBK A;  4LTV A;  3IPI A;  5E8K A;  3WCH A;  4KPD A;  3APZ A;  4GA3 A;  1WY0 A;  5JA0 F;  1HM7 A;  3ZCD A;  3N5H F;  3B7L A;  2E95 A;  3KRO B;  2F9K F;  5B02 A;  3OAB A;  4FP4 A;  3UCA A;  3ZL6 A;  4F6V A;  1KIZ A;  5AEL A;  1V4I A;  5CG5 A;  3ADZ A;  3WCB A;  1WL3 A;  3QKC A;  3VJA A;  5JV0 F;  1YHK A;  3WEK A;  3WC9 A;  2OGD A;  2AZJ A;  3SDQ A;  4LFE A;  2F7M F;  3WCL A;  4GP1 A;  1N1B A;  1JFA A;  5DGM F;  5DGS F;  4DI5 A;  1N21 A;  3Q2Z A;  3ZOU A;  3N0G A;  4RXD A;  3WCD A;  1VG3 A;  3WJN A;  2Q9Z A;  3TS7 A;  4JZX A;  3PDE A;  3AQC B;  1V4K A;  3PYA A;  4JXY A;  5HN7 A;  4P0W A;  3WJK A;  1FPS A;  3N3D A;  2FTZ A;  3N3L F;  3WCG A;  4LLT A;  5KSX F;  1PS1 A;  1N20 A;  4QXS F;  4KPJ A;  4NFI F;  3WJO A;  4FJQ A;  5IVG A;  3PKO A;  3MZV A;  4PVX F;  2EWG A;  2AZK A;  1YYR A;  1VG2 A;  5EAT A;  5E8H A;  2J1O A;  3VJ9 A;  4GP2 A;  2OPN A;  4XQT F;  1V4E A;  1YYU A;  3CKE A;  2I19 A;  5IK9 A;  5B0L A;  2AET A;  2FOR A;  3ICZ A;  2Z78 A;  4LUU A;  5ER8 A;  5B03 A;  5ERM A;  2ZY1 A;  4OGU A;  5ERO A;  4KQS A;  2OA6 A;  4KQU A;  4NUA A;  3VJB A;  3P41 A;  5IK6 A;  5E8L A;  3WE9 A;  4KFA A;  4P0V A;  1HXC A;  3KRA A;  2J5C A;  2ONG A;  1YJ4 A;  5AHU B;  3WEF A;  2P1C A;  2E8W A;  5IN8 A;  3ACY A;  4OMG A;  5DHK A;  3ZMC A;  2Z7H A;  3WSA A;  3ICN A;  4QPF A;  3P5R A;  5IKA A;  3AQ0 A;  4DXJ A;  4KWD A;  3TC1 A;  2F89 F;  2PS4 A;  3ICK A;  3SDV A;  3N0F A;  4F6X A;  3LVS A;  3N6K F;  3KB9 A;  5AYP A;  5ILD A;  1VG6 A;  2Q80 A;  3EFQ A;  1WL0 A;  3KRO A;  2E4O A;  2E8T A;  3DYF A;  1UBY A;  5IMN A;  5JUZ F;  3EZ3 A;  5HN9 A;  3V1X A;  4LOB A;  3NF2 A;  3CP6 A;  5DHI A;  3WEG A;  5ILZ A;  5DJP F;  1WL2 A;  5A0I A;  2QIS A;  3TFP A;  4EA1 A;  4LZC A;  1YYT A;  2F94 F;  5A0K A;  1VG7 A;  4KVY A;  2DH4 A;  4MC3 A;  1N22 A;  3BNX A;  4GAX A;  2ZCO A;  4LA5 A;  2Z7I A;  3WEJ A;  5DJV F;  2E92 A;  3P5P A;  3WCE A;  4NKF A;  3KRC B;  3KRF A;  3OAC A;  4OMH A;  3NPK A;  3ID0 A;  4DZW A;  2E8U A;  5ERN A;  4KKM A;  4PVY F;  5HNA A;  1YHL A;  3N46 F;  2ONH A;  1YYQ A;  3S4J A;  3ICM A;  3P8L A;  4MC0 A;  3VJ8 A;  5IL8 A;  3KRP A;  1WMW A;  2O1O A;  1UBV A;  1ZW5 A;  4DHD A;  4RYP A;  5ILK A;  2ZCR A;  5DGN F;  3SDT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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