3N49F

Human fpps complex with nov_292
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
343
structure length
343
Chain Sequence
DVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords FARNESYL PYROPHOSPHATE SYNTHASE
total genus 132
structure length 343
sequence length 343
ec nomenclature ec 2.5.1.1: Dimethylallyltranstransferase.
pdb deposition date 2010-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF00348 polyprenyl_synt Polyprenyl synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3n49F00
4OMGA 3VJ8A 4E9ZA 4UMJA 4N1ZF 2Z4ZA 3IBAA 5ILIA 5EROA 4P0WA 2E93A 4RXCA 3AE0A 5ILYA 4LFEA 3N46F 2EWGA 4NFKF 4HD1A 3LZ9A 1N1ZA 3BNYA 4P0XA 3EFQA 5DHKA 3BNXA 2PS7A 1YYSA 3QQVA 3LG5A 3ZCDA 4LXWA 5IKAA 1DGPA 2ZCOA 4E9UA 1YV5A 5JV2F 4JXYA 4LLSA 2E8XA 2E94A 5IL3A 3ICKA 1HXGA 3WJNA 3ICZA 1N22A 3VJCA 4RXAA 4DWBA 5DJRF 5HN8A 3TS7A 5IN8A 2F89F 3M02A 5EATA 2F7MF 3P5PA 5HN7A 4JXNA 5HN9A 3PYBA 2PS8A 4PVXF 2OPMA 1VG3A 5IK6A 2Z7HA 1KIZA 3OACA 4KKMA 3RBMA 3WCCA 3WSAA 3V66A 3ZMCA 4LZ3A 1WKZA 2F8CF 3KRCB 1YHMA 3N49F 4RYPA 4KFAA 4RXEA 3AQCB 3WCDA 2Z4XA 4E1EA 3UCAA 5AHUB 4GAXA 3ACWA 3LLWA 4H5EF 3WEJA 1VG6A 2OA6A 2ONGA 2QISA 3PH7A 3N3DA 3LGKA 5DW7A 1YJ4A 5JA0F 5B0JA 3N5HF 3ICMA 4LA5A 3WCLA 3Q2QA 3WCEA 4EA2A 4WK5A 2J5CA 2PS6A 3ACXA 5DIQF 4NKEA 4KVDA 5IMPA 5AFXA 2E91A 1N1BA 4XQTF 5DJVF 2Q80A 4DEMF 2AETA 1RTRA 2RAHA 3NRIA 1YYUA 2Z7IA 5ER8A 4RNQA 3WEGA 5B01A 2AZKA 1UBYA 3SDTA 4Q23A 3WE9A 2PS4A 3QKCA 3NPKA 2F92F 3AQBB 3SDQA 3LDWA 4KVIA 3WCGA 5E8HA 3SDVA 5E8LA 4RXDA 4QXSF 1VG7A 1DI1A 4JYXA 2Q9ZA 3LMDA 5B0IA 3WEKA 5IK0A 3EZ3A 4XQSF 4JZBA 3V1XA 4DZWA 3M9UA 4MC3A 2FORA 2Z78A 5DZ2A 3VJBA 5ILKA 2ZEVA 3WEHA 2FTZA 3N1WF 5ILDA 1KIYA 3WCFA 3DYFA 2E90A 4LOBA 1JFAA 4LTVA 5AYPA 5IM1A 2Z4WA 3W7FA 3KRPA 4K10A 1YYQA 3IPIA 2Q9YA 3OABB 4KK2A 3N6KF 4JZXA 4NG6A 3WCAA 1HX9A 4H5DF 4LIXA 5E8KA 1RQIA 5B03A 3WSBA 1WL3A 3DYGA 1JFGA 3EGTA 1WL0A 3WJKA 1YHLA 5B0MA 4OGUA 2AZJA 3P8RA 2Z50A 3SAEA 1N23A 5EAUA 2F94F 4DHDA 3ID0A 3PKOA 5ILZA 2I19A 1PS1A 4KUXA 4MC0A 1V4HA 3PDEA 1HXCA 3PYAA 5IL8A 3CC9A 4MC8A 3ZL6A 4PVYF 4KVYA 2Z52A 2E8VA 5A0JA 4NFJF 3VJDA 4LPHF 2VF6A 3TFPA 1RQJA 1ZW5A 2F9KF 3N1VF 4QPFA 3Q30A 3CKEA 3RMGA 3LOMA 3N0GA 3OABA 4NFIF 3SDRA 1HXAA 3V1VA 3WJOA 5B02A 3S9VA 1VG4A 3SDUA 3ICNA 1EZFA 2Z4VA 2J1PA 3KRPB 3ZOUA 2ZCQA 5ILHA 5IMNA 1HM4A 2AEKA 3LGZB 3NF2A 1UBWA 3KRFA 2OPNA 4LLTA 5CG6A 3DYHA 3KROB 5JUZF 3ACYA 5I1UA 3VJEA 1V4IA 2ZCRA 4LUUA 5AELA 2E92A 1FPSA 4DI5A 1UBVA 3N45F 3N5JF 2F8ZF 4L2XF 4DWGA 1N20A 4KQUA 3NPRA 4KPJA 3KRAB 5A0KA 3ASXA 5JV0F 3N3LF 5IVGA 4JVJF 5H9DA 2E8UA 3ADZA 3WC9A 5DJPF 3RYEA 5ILJA 3M0GA 5IMIA 3KB9A 4LA6A 3LSNA 1V4EA 2H8OA 1V4JA 2ZEUA 3APZA 5IK9A 5IKHA 3KBKA 5JV1F 4P0VA 4KPDA 1YQ7A 2DH4A 3VJAA 2E8WA 3CP6A 5B00A 4KWDA 4LTZA 1WY0A 4EA0A 5B0KA 4KQSA 4LZ0A 3G4DA 4KQ5A 1YYRA 3WEFA 1V4KA 3WCHA 5A0IA 3KROA 3P41A 3WEIA 5EASA 3RYWA 3LJIA 2Q58A 5DGNF 2O1OA 3KRFB 3WCIA 3P5RA 5KSXF 5DHIA 4NKFA 3LEEA 2ZCSA 1WMWA 4ZQ8A 3KRAA 4LFGA 3TFNA 5HNAA 3OYRA 4F62A 4LFVF 4GA3A 3WCMA 4OKZA 3LK5A 2ZY1A 1UBXA 2AELA 3M01A 5B0LA 2Z4YA 2E8TA 2PS5A 4LPGF 1HM7A 2AZLA 4N9UA 4XQRF 2J1OA 3ZMBA 1WL1A 1YYTA 5DGMF 3LVSA 5C05A 4NUAA 4KVWA 3Q2ZA 4FJQA 5ERMA 4F6VA 3Q1OA 1N24A 4LZCA 4OMHA 3P8LA 3MZVA 3N0FA 3WCJA 3M00A 5DGSF 3TC1A 3S4JA 4OKMA 1VG2A 2OGDA 4F6XA 1N21A 4GP1A 3AQ0A 5ERNA 4EA1A 3TFVA 1WL2A 2E4OA 4FP4A 2E95A 3MAVA 4GP2A 4DXJA 3B7LA 3VJ9A 5CG5A 4H5CF 1YHKA 3KRCA 2ONHA 3WCBA 2P1CA 3OACB 3G4FA
chains in the Genus database with same CATH superfamily
4OMGA 3VJ8A 4E9ZA 4UMJA 4N1ZF 2Z4ZA 3IBAA 5ILIA 5EROA 4P0WA 2E93A 4RXCA 3AE0A 5ILYA 4LFEA 3N46F 2EWGA 4NFKF 4HD1A 3LZ9A 1N1ZA 3BNYA 4P0XA 3EFQA 5DHKA 3BNXA 2PS7A 1YYSA 3QQVA 3LG5A 3ZCDA 4LXWA 5IKAA 1DGPA 2ZCOA 4E9UA 1YV5A 5JV2F 4JXYA 4LLSA 2E8XA 2E94A 5IL3A 3ICKA 1HXGA 3WJNA 3ICZA 1N22A 3VJCA 4RXAA 4DWBA 5DJRF 5HN8A 3TS7A 5IN8A 2F89F 3M02A 5EATA 2F7MF 3P5PA 5HN7A 4JXNA 5HN9A 3PYBA 2PS8A 4PVXF 2OPMA 1VG3A 5IK6A 2Z7HA 1KIZA 3OACA 4KKMA 3RBMA 3WCCA 3WSAA 3V66A 3ZMCA 4LZ3A 1WKZA 2F8CF 3KRCB 1YHMA 3N49F 4RYPA 4KFAA 4RXEA 3AQCB 3WCDA 2Z4XA 4E1EA 3UCAA 5AHUB 4GAXA 3ACWA 3LLWA 4H5EF 3WEJA 1VG6A 2OA6A 2ONGA 2QISA 3PH7A 3N3DA 3LGKA 5DW7A 1YJ4A 5JA0F 5B0JA 3N5HF 3ICMA 4LA5A 3WCLA 3Q2QA 3WCEA 4EA2A 4WK5A 2J5CA 2PS6A 3ACXA 5DIQF 4NKEA 4KVDA 5IMPA 5AFXA 2E91A 1N1BA 4XQTF 5DJVF 2Q80A 4DEMF 2AETA 1RTRA 2RAHA 3NRIA 1YYUA 2Z7IA 5ER8A 4RNQA 3WEGA 5B01A 2AZKA 1UBYA 3SDTA 4Q23A 3WE9A 2PS4A 3QKCA 3NPKA 2F92F 3AQBB 3SDQA 3LDWA 4KVIA 3WCGA 5E8HA 3SDVA 5E8LA 4RXDA 4QXSF 1VG7A 1DI1A 4JYXA 2Q9ZA 3LMDA 5B0IA 3WEKA 5IK0A 3EZ3A 4XQSF 4JZBA 3V1XA 4DZWA 3M9UA 4MC3A 2FORA 2Z78A 5DZ2A 3VJBA 5ILKA 2ZEVA 3WEHA 2FTZA 3N1WF 5ILDA 1KIYA 3WCFA 3DYFA 2E90A 4LOBA 1JFAA 4LTVA 5AYPA 5IM1A 2Z4WA 3W7FA 3KRPA 4K10A 1YYQA 3IPIA 2Q9YA 3OABB 4KK2A 3N6KF 4JZXA 4NG6A 3WCAA 1HX9A 4H5DF 4LIXA 5E8KA 1RQIA 5B03A 3WSBA 1WL3A 3DYGA 1JFGA 3EGTA 1WL0A 3WJKA 1YHLA 5B0MA 4OGUA 2AZJA 3P8RA 2Z50A 3SAEA 1N23A 5EAUA 2F94F 4DHDA 3ID0A 3PKOA 5ILZA 2I19A 1PS1A 4KUXA 4MC0A 1V4HA 3PDEA 1HXCA 3PYAA 5IL8A 3CC9A 4MC8A 3ZL6A 4PVYF 4KVYA 2Z52A 2E8VA 5A0JA 4NFJF 3VJDA 4LPHF 2VF6A 3TFPA 1RQJA 1ZW5A 2F9KF 3N1VF 4QPFA 3Q30A 3CKEA 3RMGA 3LOMA 3N0GA 3OABA 4NFIF 3SDRA 1HXAA 3V1VA 3WJOA 5B02A 3S9VA 1VG4A 3SDUA 3ICNA 1EZFA 2Z4VA 2J1PA 3KRPB 3ZOUA 2ZCQA 5ILHA 5IMNA 1HM4A 2AEKA 3LGZB 3NF2A 1UBWA 3KRFA 2OPNA 4LLTA 5CG6A 3DYHA 3KROB 5JUZF 3ACYA 5I1UA 3VJEA 1V4IA 2ZCRA 4LUUA 5AELA 2E92A 1FPSA 4DI5A 1UBVA 3N45F 3N5JF 2F8ZF 4L2XF 4DWGA 1N20A 4KQUA 3NPRA 4KPJA 3KRAB 5A0KA 3ASXA 5JV0F 3N3LF 5IVGA 4JVJF 5H9DA 2E8UA 3ADZA 3WC9A 5DJPF 3RYEA 5ILJA 3M0GA 5IMIA 3KB9A 4LA6A 3LSNA 1V4EA 2H8OA 1V4JA 2ZEUA 3APZA 5IK9A 5IKHA 3KBKA 5JV1F 4P0VA 4KPDA 1YQ7A 2DH4A 3VJAA 2E8WA 3CP6A 5B00A 4KWDA 4LTZA 1WY0A 4EA0A 5B0KA 4KQSA 4LZ0A 3G4DA 4KQ5A 1YYRA 3WEFA 1V4KA 3WCHA 5A0IA 3KROA 3P41A 3WEIA 5EASA 3RYWA 3LJIA 2Q58A 5DGNF 2O1OA 3KRFB 3WCIA 3P5RA 5KSXF 5DHIA 4NKFA 3LEEA 2ZCSA 1WMWA 4ZQ8A 3KRAA 4LFGA 3TFNA 5HNAA 3OYRA 4F62A 4LFVF 4GA3A 3WCMA 4OKZA 3LK5A 2ZY1A 1UBXA 2AELA 3M01A 5B0LA 2Z4YA 2E8TA 2PS5A 4LPGF 1HM7A 2AZLA 4N9UA 4XQRF 2J1OA 3ZMBA 1WL1A 1YYTA 5DGMF 3LVSA 5C05A 4NUAA 4KVWA 3Q2ZA 4FJQA 5ERMA 4F6VA 3Q1OA 1N24A 4LZCA 4OMHA 3P8LA 3MZVA 3N0FA 3WCJA 3M00A 5DGSF 3TC1A 3S4JA 4OKMA 1VG2A 2OGDA 4F6XA 1N21A 4GP1A 3AQ0A 5ERNA 4EA1A 3TFVA 1WL2A 2E4OA 4FP4A 2E95A 3MAVA 4GP2A 4DXJA 3B7LA 3VJ9A 5CG5A 4H5CF 1YHKA 3KRCA 2ONHA 3WCBA 2P1CA 3OACB 3G4FA
chains in the Genus database with same CATH topology
4OMGA 3VJ8A 4E9ZA 4UMJA 4N1ZF 2Z4ZA 3IBAA 5ILIA 5EROA 4P0WA 2E93A 4RXCA 3AE0A 5ILYA 4LFEA 3N46F 2EWGA 4NFKF 4HD1A 3LZ9A 1N1ZA 3BNYA 4P0XA 3EFQA 5DHKA 3BNXA 2PS7A 1YYSA 3QQVA 3LG5A 3ZCDA 4LXWA 5IKAA 1DGPA 2ZCOA 4E9UA 1YV5A 5JV2F 4JXYA 4LLSA 2E8XA 2E94A 5IL3A 3ICKA 1HXGA 3WJNA 3ICZA 1N22A 3VJCA 4RXAA 4DWBA 5DJRF 5HN8A 3TS7A 5IN8A 2F89F 3M02A 5EATA 2F7MF 3P5PA 5HN7A 4JXNA 5HN9A 3PYBA 2PS8A 4PVXF 2OPMA 1VG3A 5IK6A 2Z7HA 1KIZA 3OACA 4KKMA 3RBMA 3WCCA 3WSAA 3V66A 3ZMCA 4LZ3A 1WKZA 2F8CF 3KRCB 1YHMA 3N49F 4RYPA 4KFAA 4RXEA 3AQCB 3WCDA 2Z4XA 4E1EA 3UCAA 5AHUB 4GAXA 3ACWA 3LLWA 4H5EF 3WEJA 1VG6A 2OA6A 2ONGA 2QISA 3PH7A 3N3DA 3LGKA 5DW7A 1YJ4A 5JA0F 5B0JA 3N5HF 3ICMA 4LA5A 3WCLA 3Q2QA 3WCEA 4EA2A 4WK5A 2J5CA 2PS6A 3ACXA 5DIQF 4NKEA 4KVDA 5IMPA 5AFXA 2E91A 1N1BA 4XQTF 5DJVF 2Q80A 4DEMF 2AETA 1RTRA 2RAHA 3NRIA 1YYUA 2Z7IA 5ER8A 4RNQA 3WEGA 5B01A 2AZKA 1UBYA 3SDTA 4Q23A 3WE9A 2PS4A 3QKCA 3NPKA 2F92F 3AQBB 3SDQA 3LDWA 4KVIA 3WCGA 5E8HA 3SDVA 5E8LA 4RXDA 4QXSF 1VG7A 1DI1A 4JYXA 2Q9ZA 3LMDA 5B0IA 3WEKA 5IK0A 3EZ3A 4XQSF 4JZBA 3V1XA 4DZWA 3M9UA 4MC3A 2FORA 2Z78A 5DZ2A 3VJBA 5ILKA 2ZEVA 3WEHA 2FTZA 3N1WF 5ILDA 1KIYA 3WCFA 3DYFA 2E90A 4LOBA 1JFAA 4LTVA 5AYPA 5IM1A 2Z4WA 3W7FA 3KRPA 4K10A 1YYQA 3IPIA 2Q9YA 3OABB 4KK2A 3N6KF 4JZXA 4NG6A 3WCAA 1HX9A 4H5DF 4LIXA 5E8KA 1RQIA 5B03A 3WSBA 1WL3A 3DYGA 1JFGA 3EGTA 1WL0A 3WJKA 1YHLA 5B0MA 4OGUA 2AZJA 3P8RA 2Z50A 3SAEA 1N23A 5EAUA 2F94F 4DHDA 3ID0A 3PKOA 5ILZA 2I19A 1PS1A 4KUXA 4MC0A 1V4HA 3PDEA 1HXCA 3PYAA 5IL8A 3CC9A 4MC8A 3ZL6A 4PVYF 4KVYA 2Z52A 2E8VA 5A0JA 4NFJF 3VJDA 4LPHF 2VF6A 3TFPA 1RQJA 1ZW5A 2F9KF 3N1VF 4QPFA 3Q30A 3CKEA 3RMGA 3LOMA 3N0GA 3OABA 4NFIF 3SDRA 1HXAA 3V1VA 3WJOA 5B02A 3S9VA 1VG4A 3SDUA 3ICNA 1EZFA 2Z4VA 2J1PA 3KRPB 3ZOUA 2ZCQA 5ILHA 5IMNA 1HM4A 2AEKA 3LGZB 3NF2A 1UBWA 3KRFA 2OPNA 4LLTA 5CG6A 3DYHA 3KROB 5JUZF 3ACYA 5I1UA 3VJEA 1V4IA 2ZCRA 4LUUA 5AELA 2E92A 1FPSA 4DI5A 1UBVA 3N45F 3N5JF 2F8ZF 4L2XF 4DWGA 1N20A 4KQUA 3NPRA 4KPJA 3KRAB 5A0KA 3ASXA 5JV0F 3N3LF 5IVGA 4JVJF 5H9DA 2E8UA 3ADZA 3WC9A 5DJPF 3RYEA 5ILJA 3M0GA 5IMIA 3KB9A 4LA6A 3LSNA 1V4EA 2H8OA 1V4JA 2ZEUA 3APZA 5IK9A 5IKHA 3KBKA 5JV1F 4P0VA 4KPDA 1YQ7A 2DH4A 3VJAA 2E8WA 3CP6A 5B00A 4KWDA 4LTZA 1WY0A 4EA0A 5B0KA 4KQSA 4LZ0A 3G4DA 4KQ5A 1YYRA 3WEFA 1V4KA 3WCHA 5A0IA 3KROA 3P41A 3WEIA 5EASA 3RYWA 3LJIA 2Q58A 5DGNF 2O1OA 3KRFB 3WCIA 3P5RA 5KSXF 5DHIA 4NKFA 3LEEA 2ZCSA 1WMWA 4ZQ8A 3KRAA 4LFGA 3TFNA 5HNAA 3OYRA 4F62A 4LFVF 4GA3A 3WCMA 4OKZA 3LK5A 2ZY1A 1UBXA 2AELA 3M01A 5B0LA 2Z4YA 2E8TA 2PS5A 4LPGF 1HM7A 2AZLA 4N9UA 4XQRF 2J1OA 3ZMBA 1WL1A 1YYTA 5DGMF 3LVSA 5C05A 4NUAA 4KVWA 3Q2ZA 4FJQA 5ERMA 4F6VA 3Q1OA 1N24A 4LZCA 4OMHA 3P8LA 3MZVA 3N0FA 3WCJA 3M00A 5DGSF 3TC1A 3S4JA 4OKMA 1VG2A 2OGDA 4F6XA 1N21A 4GP1A 3AQ0A 5ERNA 4EA1A 3TFVA 1WL2A 2E4OA 4FP4A 2E95A 3MAVA 4GP2A 4DXJA 3B7LA 3VJ9A 5CG5A 4H5CF 1YHKA 3KRCA 2ONHA 3WCBA 2P1CA 3OACB 3G4FA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4OMG A;  3VJ8 A;  4E9Z A;  4UMJ A;  4N1Z F;  2Z4Z A;  3IBA A;  5ILI A;  5ERO A;  4P0W A;  2E93 A;  4RXC A;  3AE0 A;  5ILY A;  4LFE A;  3N46 F;  2EWG A;  4NFK F;  4HD1 A;  3LZ9 A;  1N1Z A;  3BNY A;  4P0X A;  3EFQ A;  5DHK A;  3BNX A;  2PS7 A;  1YYS A;  3QQV A;  3LG5 A;  3ZCD A;  4LXW A;  5IKA A;  1DGP A;  2ZCO A;  4E9U A;  1YV5 A;  5JV2 F;  4JXY A;  4LLS A;  2E8X A;  2E94 A;  5IL3 A;  3ICK A;  1HXG A;  3WJN A;  3ICZ A;  1N22 A;  3VJC A;  4RXA A;  4DWB A;  5DJR F;  5HN8 A;  3TS7 A;  5IN8 A;  2F89 F;  3M02 A;  5EAT A;  2F7M F;  3P5P A;  5HN7 A;  4JXN A;  5HN9 A;  3PYB A;  2PS8 A;  4PVX F;  2OPM A;  1VG3 A;  5IK6 A;  2Z7H A;  1KIZ A;  3OAC A;  4KKM A;  3RBM A;  3WCC A;  3WSA A;  3V66 A;  3ZMC A;  4LZ3 A;  1WKZ A;  2F8C F;  3KRC B;  1YHM A;  3N49 F;  4RYP A;  4KFA A;  4RXE A;  3AQC B;  3WCD A;  2Z4X A;  4E1E A;  3UCA A;  5AHU B;  4GAX A;  3ACW A;  3LLW A;  4H5E F;  3WEJ A;  1VG6 A;  2OA6 A;  2ONG A;  2QIS A;  3PH7 A;  3N3D A;  3LGK A;  5DW7 A;  1YJ4 A;  5JA0 F;  5B0J A;  3N5H F;  3ICM A;  4LA5 A;  3WCL A;  3Q2Q A;  3WCE A;  4EA2 A;  4WK5 A;  2J5C A;  2PS6 A;  3ACX A;  5DIQ F;  4NKE A;  4KVD A;  5IMP A;  5AFX A;  2E91 A;  1N1B A;  4XQT F;  5DJV F;  2Q80 A;  4DEM F;  2AET A;  1RTR A;  2RAH A;  3NRI A;  1YYU A;  2Z7I A;  5ER8 A;  4RNQ A;  3WEG A;  5B01 A;  2AZK A;  1UBY A;  3SDT A;  4Q23 A;  3WE9 A;  2PS4 A;  3QKC A;  3NPK A;  2F92 F;  3AQB B;  3SDQ A;  3LDW A;  4KVI A;  3WCG A;  5E8H A;  3SDV A;  5E8L A;  4RXD A;  4QXS F;  1VG7 A;  1DI1 A;  4JYX A;  2Q9Z A;  3LMD A;  5B0I A;  3WEK A;  5IK0 A;  3EZ3 A;  4XQS F;  4JZB A;  3V1X A;  4DZW A;  3M9U A;  4MC3 A;  2FOR A;  2Z78 A;  5DZ2 A;  3VJB A;  5ILK A;  2ZEV A;  3WEH A;  2FTZ A;  3N1W F;  5ILD A;  1KIY A;  3WCF A;  3DYF A;  2E90 A;  4LOB A;  1JFA A;  4LTV A;  5AYP A;  5IM1 A;  2Z4W A;  3W7F A;  3KRP A;  4K10 A;  1YYQ A;  3IPI A;  2Q9Y A;  3OAB B;  4KK2 A;  3N6K F;  4JZX A;  4NG6 A;  3WCA A;  1HX9 A;  4H5D F;  4LIX A;  5E8K A;  1RQI A;  5B03 A;  3WSB A;  1WL3 A;  3DYG A;  1JFG A;  3EGT A;  1WL0 A;  3WJK A;  1YHL A;  5B0M A;  4OGU A;  2AZJ A;  3P8R A;  2Z50 A;  3SAE A;  1N23 A;  5EAU A;  2F94 F;  4DHD A;  3ID0 A;  3PKO A;  5ILZ A;  2I19 A;  1PS1 A;  4KUX A;  4MC0 A;  1V4H A;  3PDE A;  1HXC A;  3PYA A;  5IL8 A;  3CC9 A;  4MC8 A;  3ZL6 A;  4PVY F;  4KVY A;  2Z52 A;  2E8V A;  5A0J A;  4NFJ F;  3VJD A;  4LPH F;  2VF6 A;  3TFP A;  1RQJ A;  1ZW5 A;  2F9K F;  3N1V F;  4QPF A;  3Q30 A;  3CKE A;  3RMG A;  3LOM A;  3N0G A;  3OAB A;  4NFI F;  3SDR A;  1HXA A;  3V1V A;  3WJO A;  5B02 A;  3S9V A;  1VG4 A;  3SDU A;  3ICN A;  1EZF A;  2Z4V A;  2J1P A;  3KRP B;  3ZOU A;  2ZCQ A;  5ILH A;  5IMN A;  1HM4 A;  2AEK A;  3LGZ B;  3NF2 A;  1UBW A;  3KRF A;  2OPN A;  4LLT A;  5CG6 A;  3DYH A;  3KRO B;  5JUZ F;  3ACY A;  5I1U A;  3VJE A;  1V4I A;  2ZCR A;  4LUU A;  5AEL A;  2E92 A;  1FPS A;  4DI5 A;  1UBV A;  3N45 F;  3N5J F;  2F8Z F;  4L2X F;  4DWG A;  1N20 A;  4KQU A;  3NPR A;  4KPJ A;  3KRA B;  5A0K A;  3ASX A;  5JV0 F;  3N3L F;  5IVG A;  4JVJ F;  5H9D A;  2E8U A;  3ADZ A;  3WC9 A;  5DJP F;  3RYE A;  5ILJ A;  3M0G A;  5IMI A;  3KB9 A;  4LA6 A;  3LSN A;  1V4E A;  2H8O A;  1V4J A;  2ZEU A;  3APZ A;  5IK9 A;  5IKH A;  3KBK A;  5JV1 F;  4P0V A;  4KPD A;  1YQ7 A;  2DH4 A;  3VJA A;  2E8W A;  3CP6 A;  5B00 A;  4KWD A;  4LTZ A;  1WY0 A;  4EA0 A;  5B0K A;  4KQS A;  4LZ0 A;  3G4D A;  4KQ5 A;  1YYR A;  3WEF A;  1V4K A;  3WCH A;  5A0I A;  3KRO A;  3P41 A;  3WEI A;  5EAS A;  3RYW A;  3LJI A;  2Q58 A;  5DGN F;  2O1O A;  3KRF B;  3WCI A;  3P5R A;  5KSX F;  5DHI A;  4NKF A;  3LEE A;  2ZCS A;  1WMW A;  4ZQ8 A;  3KRA A;  4LFG A;  3TFN A;  5HNA A;  3OYR A;  4F62 A;  4LFV F;  4GA3 A;  3WCM A;  4OKZ A;  3LK5 A;  2ZY1 A;  1UBX A;  2AEL A;  3M01 A;  5B0L A;  2Z4Y A;  2E8T A;  2PS5 A;  4LPG F;  1HM7 A;  2AZL A;  4N9U A;  4XQR F;  2J1O A;  3ZMB A;  1WL1 A;  1YYT A;  5DGM F;  3LVS A;  5C05 A;  4NUA A;  4KVW A;  3Q2Z A;  4FJQ A;  5ERM A;  4F6V A;  3Q1O A;  1N24 A;  4LZC A;  4OMH A;  3P8L A;  3MZV A;  3N0F A;  3WCJ A;  3M00 A;  5DGS F;  3TC1 A;  3S4J A;  4OKM A;  1VG2 A;  2OGD A;  4F6X A;  1N21 A;  4GP1 A;  3AQ0 A;  5ERN A;  4EA1 A;  3TFV A;  1WL2 A;  2E4O A;  4FP4 A;  2E95 A;  3MAV A;  4GP2 A;  4DXJ A;  3B7L A;  3VJ9 A;  5CG5 A;  4H5C F;  1YHK A;  3KRC A;  2ONH A;  3WCB A;  2P1C A;  3OAC B;  3G4F A; 
#chains in the Genus database with same CATH topology
 4OMG A;  3VJ8 A;  4E9Z A;  4UMJ A;  4N1Z F;  2Z4Z A;  3IBA A;  5ILI A;  5ERO A;  4P0W A;  2E93 A;  4RXC A;  3AE0 A;  5ILY A;  4LFE A;  3N46 F;  2EWG A;  4NFK F;  4HD1 A;  3LZ9 A;  1N1Z A;  3BNY A;  4P0X A;  3EFQ A;  5DHK A;  3BNX A;  2PS7 A;  1YYS A;  3QQV A;  3LG5 A;  3ZCD A;  4LXW A;  5IKA A;  1DGP A;  2ZCO A;  4E9U A;  1YV5 A;  5JV2 F;  4JXY A;  4LLS A;  2E8X A;  2E94 A;  5IL3 A;  3ICK A;  1HXG A;  3WJN A;  3ICZ A;  1N22 A;  3VJC A;  4RXA A;  4DWB A;  5DJR F;  5HN8 A;  3TS7 A;  5IN8 A;  2F89 F;  3M02 A;  5EAT A;  2F7M F;  3P5P A;  5HN7 A;  4JXN A;  5HN9 A;  3PYB A;  2PS8 A;  4PVX F;  2OPM A;  1VG3 A;  5IK6 A;  2Z7H A;  1KIZ A;  3OAC A;  4KKM A;  3RBM A;  3WCC A;  3WSA A;  3V66 A;  3ZMC A;  4LZ3 A;  1WKZ A;  2F8C F;  3KRC B;  1YHM A;  3N49 F;  4RYP A;  4KFA A;  4RXE A;  3AQC B;  3WCD A;  2Z4X A;  4E1E A;  3UCA A;  5AHU B;  4GAX A;  3ACW A;  3LLW A;  4H5E F;  3WEJ A;  1VG6 A;  2OA6 A;  2ONG A;  2QIS A;  3PH7 A;  3N3D A;  3LGK A;  5DW7 A;  1YJ4 A;  5JA0 F;  5B0J A;  3N5H F;  3ICM A;  4LA5 A;  3WCL A;  3Q2Q A;  3WCE A;  4EA2 A;  4WK5 A;  2J5C A;  2PS6 A;  3ACX A;  5DIQ F;  4NKE A;  4KVD A;  5IMP A;  5AFX A;  2E91 A;  1N1B A;  4XQT F;  5DJV F;  2Q80 A;  4DEM F;  2AET A;  1RTR A;  2RAH A;  3NRI A;  1YYU A;  2Z7I A;  5ER8 A;  4RNQ A;  3WEG A;  5B01 A;  2AZK A;  1UBY A;  3SDT A;  4Q23 A;  3WE9 A;  2PS4 A;  3QKC A;  3NPK A;  2F92 F;  3AQB B;  3SDQ A;  3LDW A;  4KVI A;  3WCG A;  5E8H A;  3SDV A;  5E8L A;  4RXD A;  4QXS F;  1VG7 A;  1DI1 A;  4JYX A;  2Q9Z A;  3LMD A;  5B0I A;  3WEK A;  5IK0 A;  3EZ3 A;  4XQS F;  4JZB A;  3V1X A;  4DZW A;  3M9U A;  4MC3 A;  2FOR A;  2Z78 A;  5DZ2 A;  3VJB A;  5ILK A;  2ZEV A;  3WEH A;  2FTZ A;  3N1W F;  5ILD A;  1KIY A;  3WCF A;  3DYF A;  2E90 A;  4LOB A;  1JFA A;  4LTV A;  5AYP A;  5IM1 A;  2Z4W A;  3W7F A;  3KRP A;  4K10 A;  1YYQ A;  3IPI A;  2Q9Y A;  3OAB B;  4KK2 A;  3N6K F;  4JZX A;  4NG6 A;  3WCA A;  1HX9 A;  4H5D F;  4LIX A;  5E8K A;  1RQI A;  5B03 A;  3WSB A;  1WL3 A;  3DYG A;  1JFG A;  3EGT A;  1WL0 A;  3WJK A;  1YHL A;  5B0M A;  4OGU A;  2AZJ A;  3P8R A;  2Z50 A;  3SAE A;  1N23 A;  5EAU A;  2F94 F;  4DHD A;  3ID0 A;  3PKO A;  5ILZ A;  2I19 A;  1PS1 A;  4KUX A;  4MC0 A;  1V4H A;  3PDE A;  1HXC A;  3PYA A;  5IL8 A;  3CC9 A;  4MC8 A;  3ZL6 A;  4PVY F;  4KVY A;  2Z52 A;  2E8V A;  5A0J A;  4NFJ F;  3VJD A;  4LPH F;  2VF6 A;  3TFP A;  1RQJ A;  1ZW5 A;  2F9K F;  3N1V F;  4QPF A;  3Q30 A;  3CKE A;  3RMG A;  3LOM A;  3N0G A;  3OAB A;  4NFI F;  3SDR A;  1HXA A;  3V1V A;  3WJO A;  5B02 A;  3S9V A;  1VG4 A;  3SDU A;  3ICN A;  1EZF A;  2Z4V A;  2J1P A;  3KRP B;  3ZOU A;  2ZCQ A;  5ILH A;  5IMN A;  1HM4 A;  2AEK A;  3LGZ B;  3NF2 A;  1UBW A;  3KRF A;  2OPN A;  4LLT A;  5CG6 A;  3DYH A;  3KRO B;  5JUZ F;  3ACY A;  5I1U A;  3VJE A;  1V4I A;  2ZCR A;  4LUU A;  5AEL A;  2E92 A;  1FPS A;  4DI5 A;  1UBV A;  3N45 F;  3N5J F;  2F8Z F;  4L2X F;  4DWG A;  1N20 A;  4KQU A;  3NPR A;  4KPJ A;  3KRA B;  5A0K A;  3ASX A;  5JV0 F;  3N3L F;  5IVG A;  4JVJ F;  5H9D A;  2E8U A;  3ADZ A;  3WC9 A;  5DJP F;  3RYE A;  5ILJ A;  3M0G A;  5IMI A;  3KB9 A;  4LA6 A;  3LSN A;  1V4E A;  2H8O A;  1V4J A;  2ZEU A;  3APZ A;  5IK9 A;  5IKH A;  3KBK A;  5JV1 F;  4P0V A;  4KPD A;  1YQ7 A;  2DH4 A;  3VJA A;  2E8W A;  3CP6 A;  5B00 A;  4KWD A;  4LTZ A;  1WY0 A;  4EA0 A;  5B0K A;  4KQS A;  4LZ0 A;  3G4D A;  4KQ5 A;  1YYR A;  3WEF A;  1V4K A;  3WCH A;  5A0I A;  3KRO A;  3P41 A;  3WEI A;  5EAS A;  3RYW A;  3LJI A;  2Q58 A;  5DGN F;  2O1O A;  3KRF B;  3WCI A;  3P5R A;  5KSX F;  5DHI A;  4NKF A;  3LEE A;  2ZCS A;  1WMW A;  4ZQ8 A;  3KRA A;  4LFG A;  3TFN A;  5HNA A;  3OYR A;  4F62 A;  4LFV F;  4GA3 A;  3WCM A;  4OKZ A;  3LK5 A;  2ZY1 A;  1UBX A;  2AEL A;  3M01 A;  5B0L A;  2Z4Y A;  2E8T A;  2PS5 A;  4LPG F;  1HM7 A;  2AZL A;  4N9U A;  4XQR F;  2J1O A;  3ZMB A;  1WL1 A;  1YYT A;  5DGM F;  3LVS A;  5C05 A;  4NUA A;  4KVW A;  3Q2Z A;  4FJQ A;  5ERM A;  4F6V A;  3Q1O A;  1N24 A;  4LZC A;  4OMH A;  3P8L A;  3MZV A;  3N0F A;  3WCJ A;  3M00 A;  5DGS F;  3TC1 A;  3S4J A;  4OKM A;  1VG2 A;  2OGD A;  4F6X A;  1N21 A;  4GP1 A;  3AQ0 A;  5ERN A;  4EA1 A;  3TFV A;  1WL2 A;  2E4O A;  4FP4 A;  2E95 A;  3MAV A;  4GP2 A;  4DXJ A;  3B7L A;  3VJ9 A;  5CG5 A;  4H5C F;  1YHK A;  3KRC A;  2ONH A;  3WCB A;  2P1C A;  3OAC B;  3G4F A; 
#chains in the Genus database with same CATH homology
 4OMG A;  3VJ8 A;  4E9Z A;  4UMJ A;  4N1Z F;  2Z4Z A;  3IBA A;  5ILI A;  5ERO A;  4P0W A;  2E93 A;  4RXC A;  3AE0 A;  5ILY A;  4LFE A;  3N46 F;  2EWG A;  4NFK F;  4HD1 A;  3LZ9 A;  1N1Z A;  3BNY A;  4P0X A;  3EFQ A;  5DHK A;  3BNX A;  2PS7 A;  1YYS A;  3QQV A;  3LG5 A;  3ZCD A;  4LXW A;  5IKA A;  1DGP A;  2ZCO A;  4E9U A;  1YV5 A;  5JV2 F;  4JXY A;  4LLS A;  2E8X A;  2E94 A;  5IL3 A;  3ICK A;  1HXG A;  3WJN A;  3ICZ A;  1N22 A;  3VJC A;  4RXA A;  4DWB A;  5DJR F;  5HN8 A;  3TS7 A;  5IN8 A;  2F89 F;  3M02 A;  5EAT A;  2F7M F;  3P5P A;  5HN7 A;  4JXN A;  5HN9 A;  3PYB A;  2PS8 A;  4PVX F;  2OPM A;  1VG3 A;  5IK6 A;  2Z7H A;  1KIZ A;  3OAC A;  4KKM A;  3RBM A;  3WCC A;  3WSA A;  3V66 A;  3ZMC A;  4LZ3 A;  1WKZ A;  2F8C F;  3KRC B;  1YHM A;  3N49 F;  4RYP A;  4KFA A;  4RXE A;  3AQC B;  3WCD A;  2Z4X A;  4E1E A;  3UCA A;  5AHU B;  4GAX A;  3ACW A;  3LLW A;  4H5E F;  3WEJ A;  1VG6 A;  2OA6 A;  2ONG A;  2QIS A;  3PH7 A;  3N3D A;  3LGK A;  5DW7 A;  1YJ4 A;  5JA0 F;  5B0J A;  3N5H F;  3ICM A;  4LA5 A;  3WCL A;  3Q2Q A;  3WCE A;  4EA2 A;  4WK5 A;  2J5C A;  2PS6 A;  3ACX A;  5DIQ F;  4NKE A;  4KVD A;  5IMP A;  5AFX A;  2E91 A;  1N1B A;  4XQT F;  5DJV F;  2Q80 A;  4DEM F;  2AET A;  1RTR A;  2RAH A;  3NRI A;  1YYU A;  2Z7I A;  5ER8 A;  4RNQ A;  3WEG A;  5B01 A;  2AZK A;  1UBY A;  3SDT A;  4Q23 A;  3WE9 A;  2PS4 A;  3QKC A;  3NPK A;  2F92 F;  3AQB B;  3SDQ A;  3LDW A;  4KVI A;  3WCG A;  5E8H A;  3SDV A;  5E8L A;  4RXD A;  4QXS F;  1VG7 A;  1DI1 A;  4JYX A;  2Q9Z A;  3LMD A;  5B0I A;  3WEK A;  5IK0 A;  3EZ3 A;  4XQS F;  4JZB A;  3V1X A;  4DZW A;  3M9U A;  4MC3 A;  2FOR A;  2Z78 A;  5DZ2 A;  3VJB A;  5ILK A;  2ZEV A;  3WEH A;  2FTZ A;  3N1W F;  5ILD A;  1KIY A;  3WCF A;  3DYF A;  2E90 A;  4LOB A;  1JFA A;  4LTV A;  5AYP A;  5IM1 A;  2Z4W A;  3W7F A;  3KRP A;  4K10 A;  1YYQ A;  3IPI A;  2Q9Y A;  3OAB B;  4KK2 A;  3N6K F;  4JZX A;  4NG6 A;  3WCA A;  1HX9 A;  4H5D F;  4LIX A;  5E8K A;  1RQI A;  5B03 A;  3WSB A;  1WL3 A;  3DYG A;  1JFG A;  3EGT A;  1WL0 A;  3WJK A;  1YHL A;  5B0M A;  4OGU A;  2AZJ A;  3P8R A;  2Z50 A;  3SAE A;  1N23 A;  5EAU A;  2F94 F;  4DHD A;  3ID0 A;  3PKO A;  5ILZ A;  2I19 A;  1PS1 A;  4KUX A;  4MC0 A;  1V4H A;  3PDE A;  1HXC A;  3PYA A;  5IL8 A;  3CC9 A;  4MC8 A;  3ZL6 A;  4PVY F;  4KVY A;  2Z52 A;  2E8V A;  5A0J A;  4NFJ F;  3VJD A;  4LPH F;  2VF6 A;  3TFP A;  1RQJ A;  1ZW5 A;  2F9K F;  3N1V F;  4QPF A;  3Q30 A;  3CKE A;  3RMG A;  3LOM A;  3N0G A;  3OAB A;  4NFI F;  3SDR A;  1HXA A;  3V1V A;  3WJO A;  5B02 A;  3S9V A;  1VG4 A;  3SDU A;  3ICN A;  1EZF A;  2Z4V A;  2J1P A;  3KRP B;  3ZOU A;  2ZCQ A;  5ILH A;  5IMN A;  1HM4 A;  2AEK A;  3LGZ B;  3NF2 A;  1UBW A;  3KRF A;  2OPN A;  4LLT A;  5CG6 A;  3DYH A;  3KRO B;  5JUZ F;  3ACY A;  5I1U A;  3VJE A;  1V4I A;  2ZCR A;  4LUU A;  5AEL A;  2E92 A;  1FPS A;  4DI5 A;  1UBV A;  3N45 F;  3N5J F;  2F8Z F;  4L2X F;  4DWG A;  1N20 A;  4KQU A;  3NPR A;  4KPJ A;  3KRA B;  5A0K A;  3ASX A;  5JV0 F;  3N3L F;  5IVG A;  4JVJ F;  5H9D A;  2E8U A;  3ADZ A;  3WC9 A;  5DJP F;  3RYE A;  5ILJ A;  3M0G A;  5IMI A;  3KB9 A;  4LA6 A;  3LSN A;  1V4E A;  2H8O A;  1V4J A;  2ZEU A;  3APZ A;  5IK9 A;  5IKH A;  3KBK A;  5JV1 F;  4P0V A;  4KPD A;  1YQ7 A;  2DH4 A;  3VJA A;  2E8W A;  3CP6 A;  5B00 A;  4KWD A;  4LTZ A;  1WY0 A;  4EA0 A;  5B0K A;  4KQS A;  4LZ0 A;  3G4D A;  4KQ5 A;  1YYR A;  3WEF A;  1V4K A;  3WCH A;  5A0I A;  3KRO A;  3P41 A;  3WEI A;  5EAS A;  3RYW A;  3LJI A;  2Q58 A;  5DGN F;  2O1O A;  3KRF B;  3WCI A;  3P5R A;  5KSX F;  5DHI A;  4NKF A;  3LEE A;  2ZCS A;  1WMW A;  4ZQ8 A;  3KRA A;  4LFG A;  3TFN A;  5HNA A;  3OYR A;  4F62 A;  4LFV F;  4GA3 A;  3WCM A;  4OKZ A;  3LK5 A;  2ZY1 A;  1UBX A;  2AEL A;  3M01 A;  5B0L A;  2Z4Y A;  2E8T A;  2PS5 A;  4LPG F;  1HM7 A;  2AZL A;  4N9U A;  4XQR F;  2J1O A;  3ZMB A;  1WL1 A;  1YYT A;  5DGM F;  3LVS A;  5C05 A;  4NUA A;  4KVW A;  3Q2Z A;  4FJQ A;  5ERM A;  4F6V A;  3Q1O A;  1N24 A;  4LZC A;  4OMH A;  3P8L A;  3MZV A;  3N0F A;  3WCJ A;  3M00 A;  5DGS F;  3TC1 A;  3S4J A;  4OKM A;  1VG2 A;  2OGD A;  4F6X A;  1N21 A;  4GP1 A;  3AQ0 A;  5ERN A;  4EA1 A;  3TFV A;  1WL2 A;  2E4O A;  4FP4 A;  2E95 A;  3MAV A;  4GP2 A;  4DXJ A;  3B7L A;  3VJ9 A;  5CG5 A;  4H5C F;  1YHK A;  3KRC A;  2ONH A;  3WCB A;  2P1C A;  3OAC B;  3G4F A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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