3Q30A

Human squalene synthase in complex with (2r,3r)-2-carboxymethoxy-3-[5-(2-naphthalenyl)pentyl]aminocarbonyl-3-[5-(2-naphthalenyl)pentyloxy]propionic acid
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
333
structure length
330
Chain Sequence
LSSSLKTCYKYLNQTSAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 137
structure length 330
sequence length 333
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2010-12-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3q30A00
1V4JA 2ONHA 5E8LA 1WMWA 4EA2A 5ILKA 1YYSA 3VJAA 3ZL6A 1V4EA 1YYRA 3LMDA 1ZW5A 2DH4A 2Z4VA 4NFJF 3V1VA 3IBAA 3Q2QA 1UBWA 2E90A 5B0MA 1HM7A 3P8RA 5AYPA 3CC9A 5B01A 5E8KA 5ERMA 2ONGA 5KSXF 3PYBA 4OMHA 3CP6A 3P41A 5JV1F 1V4KA 4LZ3A 4KVYA 4N1ZF 4KPJA 4KPDA 3M02A 1HXGA 3WEKA 3WJOA 2PS4A 1UBVA 2J5CA 2E91A 1N21A 1RQJA 3KRPB 1YV5A 3OACB 2ZCSA 3ACWA 2H8OA 2Z4XA 3KRCB 3PH7A 4KWDA 5ER8A 2Z7HA 3N0FA 3S4JA 2O1OA 3OACA 2Q9YA 3WCEA 3M9UA 3SAEA 3WEHA 3ICMA 5CG6A 2Z4YA 5E8HA 4RNQA 5IL3A 3LDWA 2ZEUA 1N24A 4MC0A 4KKMA 5ILZA 3OABB 4RXAA 1YHMA 5DW7A 4PVYF 4MC3A 3WC9A 1N22A 3OABA 5B0IA 4EA1A 1RTRA 5A0KA 4JZBA 1UBYA 2ZY1A 1WY0A 3EZ3A 3N3LF 4LFVF 4RXDA 4KUXA 2VF6A 4NKEA 5IK0A 3LGZB 4LFEA 5AELA 4JVJF 3LVSA 5IKAA 4PVXF 2AELA 3WCHA 3VJEA 2FTZA 2F8CF 4DI5A 3NPRA 4KQ5A 4JZXA 3WJKA 4RYPA 1VG6A 1WL0A 3VJCA 4OMGA 3WCAA 3RYEA 2EWGA 3SDQA 3EFQA 3UCAA 3N3DA 3PDEA 5DIQF 5B00A 1YHLA 4K10A 5IK9A 3AQ0A 2E92A 3WCIA 1UBXA 4GAXA 4LZ0A 3TFVA 2F94F 2AZKA 4NFIF 4JXNA 3WSAA 2OPMA 5IM1A 3VJDA 5EROA 4XQSF 1HXAA 3KBKA 2J1OA 4GP2A 3LG5A 2Z4ZA 2E8WA 3N49F 4XQTF 4KVIA 3WE9A 2Z50A 5ILDA 3WEGA 4KK2A 3WCDA 5JV0F 4LPHF 2F89F 5AHUB 3LK5A 2OA6A 4P0WA 3QQVA 3WCLA 1N20A 2Q9ZA 3MAVA 3SDRA 3ICZA 3P5PA 4JXYA 3N6KF 4LFGA 3SDTA 3P5RA 1EZFA 4KQUA 2Q80A 2J1PA 4QXSF 3ASXA 1VG7A 3WJNA 1HM4A 3AQCB 2E4OA 3WEJA 1DGPA 2Z78A 4F6VA 1YYQA 3N0GA 1VG3A 5B0LA 5IK6A 1V4HA 5JV2F 5DJPF 4OKZA 1YQ7A 2E95A 4JYXA 5DZ2A 1VG4A 3ID0A 2OGDA 3LEEA 1N1BA 3ICNA 4KQSA 3ZCDA 4DWBA 4NKFA 4FP4A 5DGSF 2E93A 5AFXA 1WL2A 4E9ZA 3PYAA 5C05A 4F62A 3BNYA 2ZCOA 5ERNA 5IL8A 2AETA 3S9VA 1WL1A 4DWGA 4LUUA 2F9KF 3Q1OA 4HD1A 4FJQA 3ADZA 1FPSA 4KVDA 3TC1A 5DGMF 4QPFA 3P8LA 3AE0A 3ICKA 4LXWA 1YJ4A 3Q30A 3M00A 4H5CF 1RQIA 3RMGA 2AZLA 3N46F 3LOMA 3RBMA 5HN9A 2OPNA 2ZEVA 3LGKA 3PKOA 2PS8A 1YHKA 3KROB 1KIZA 4LA5A 1JFGA 2QISA 3DYFA 3KROA 4LA6A 3M0GA 5ILHA 4WK5A 3WCMA 2E8UA 4NFKF 3TFNA 1WKZA 4L2XF 3DYHA 4DHDA 2FORA 3NF2A 4ZQ8A 5DJRF 4DZWA 5JA0F 5ILYA 2E8XA 2ZCRA 3NPKA 5ILIA 2Q58A 1N1ZA 3WCJA 2AEKA 5IMNA 4OKMA 4Q23A 4LIXA 3LZ9A 5I1UA 1PS1A 3KRFA 4P0XA 2PS7A 3TFPA 3QKCA 5B03A 3VJ9A 2F7MF 3W7FA 3MZVA 4H5DF 4LTVA 3EGTA 5EASA 3ZOUA 2RAHA 4NUAA 5IMPA 2E8VA 4RXEA 1YYTA 2ZCQA 4LLSA 5H9DA 3V1XA 3WCCA 5IKHA 3ACXA 3WSBA 3WEFA 3G4FA 3APZA 4KFAA 2Z4WA 1JFAA 3B7LA 3M01A 4LTZA 5IVGA 3KRAB 2Z7IA 1N23A 5HNAA 2PS6A 4DEMF 4LZCA 3VJ8A 5A0IA 4GP1A 3RYWA 3WCGA 3KRAA 5CG5A 4P0VA 4N9UA 1KIYA 4LPGF 4LLTA 3CKEA 3BNXA 3N5HF 4MC8A 5A0JA 5IMIA 5DJVF 1YYUA 3KRPA 3SDUA 4KVWA 3ZMBA 3TS7A 3KRCA 1HXCA 3ZMCA 1WL3A 3OYRA 4E9UA 2E94A 1V4IA 3IPIA 5DHKA 3N5JF 5DGNF 3N1VF 3WCFA 1HX9A 4EA0A 5B02A 5B0KA 3WEIA 4RXCA 3VJBA 1DI1A 3LSNA 3Q2ZA 4XQRF 3SDVA 5HN7A 5JUZF 2PS5A 5EATA 3WCBA 2E8TA 3AQBB 4NG6A 4OGUA 5HN8A 3N1WF 4F6XA 5DHIA 2F92F 5ILJA 2I19A 4GA3A 3G4DA 5IN8A 3V66A 4LOBA 5EAUA 3KB9A 3LLWA 2F8ZF 5B0JA 2P1CA 2AZJA 4E1EA 1VG2A 4H5EF 4UMJA 4DXJA 3N45F 3NRIA 3ACYA 3DYGA 2Z52A 3KRFB 3LJIA
chains in the Genus database with same CATH superfamily
1V4JA 2ONHA 5E8LA 1WMWA 4EA2A 5ILKA 1YYSA 3VJAA 3ZL6A 1V4EA 1YYRA 3LMDA 1ZW5A 2DH4A 2Z4VA 4NFJF 3V1VA 3IBAA 3Q2QA 1UBWA 2E90A 5B0MA 1HM7A 3P8RA 5AYPA 3CC9A 5B01A 5E8KA 5ERMA 2ONGA 5KSXF 3PYBA 4OMHA 3CP6A 3P41A 5JV1F 1V4KA 4LZ3A 4KVYA 4N1ZF 4KPJA 4KPDA 3M02A 1HXGA 3WEKA 3WJOA 2PS4A 1UBVA 2J5CA 2E91A 1N21A 1RQJA 3KRPB 1YV5A 3OACB 2ZCSA 3ACWA 2H8OA 2Z4XA 3KRCB 3PH7A 4KWDA 5ER8A 2Z7HA 3N0FA 3S4JA 2O1OA 3OACA 2Q9YA 3WCEA 3M9UA 3SAEA 3WEHA 3ICMA 5CG6A 2Z4YA 5E8HA 4RNQA 5IL3A 3LDWA 2ZEUA 1N24A 4MC0A 4KKMA 5ILZA 3OABB 4RXAA 1YHMA 5DW7A 4PVYF 4MC3A 3WC9A 1N22A 3OABA 5B0IA 4EA1A 1RTRA 5A0KA 4JZBA 1UBYA 2ZY1A 1WY0A 3EZ3A 3N3LF 4LFVF 4RXDA 4KUXA 2VF6A 4NKEA 5IK0A 3LGZB 4LFEA 5AELA 4JVJF 3LVSA 5IKAA 4PVXF 2AELA 3WCHA 3VJEA 2FTZA 2F8CF 4DI5A 3NPRA 4KQ5A 4JZXA 3WJKA 4RYPA 1VG6A 1WL0A 3VJCA 4OMGA 3WCAA 3RYEA 2EWGA 3SDQA 3EFQA 3UCAA 3N3DA 3PDEA 5DIQF 5B00A 1YHLA 4K10A 5IK9A 3AQ0A 2E92A 3WCIA 1UBXA 4GAXA 4LZ0A 3TFVA 2F94F 2AZKA 4NFIF 4JXNA 3WSAA 2OPMA 5IM1A 3VJDA 5EROA 4XQSF 1HXAA 3KBKA 2J1OA 4GP2A 3LG5A 2Z4ZA 2E8WA 3N49F 4XQTF 4KVIA 3WE9A 2Z50A 5ILDA 3WEGA 4KK2A 3WCDA 5JV0F 4LPHF 2F89F 5AHUB 3LK5A 2OA6A 4P0WA 3QQVA 3WCLA 1N20A 2Q9ZA 3MAVA 3SDRA 3ICZA 3P5PA 4JXYA 3N6KF 4LFGA 3SDTA 3P5RA 1EZFA 4KQUA 2Q80A 2J1PA 4QXSF 3ASXA 1VG7A 3WJNA 1HM4A 3AQCB 2E4OA 3WEJA 1DGPA 2Z78A 4F6VA 1YYQA 3N0GA 1VG3A 5B0LA 5IK6A 1V4HA 5JV2F 5DJPF 4OKZA 1YQ7A 2E95A 4JYXA 5DZ2A 1VG4A 3ID0A 2OGDA 3LEEA 1N1BA 3ICNA 4KQSA 3ZCDA 4DWBA 4NKFA 4FP4A 5DGSF 2E93A 5AFXA 1WL2A 4E9ZA 3PYAA 5C05A 4F62A 3BNYA 2ZCOA 5ERNA 5IL8A 2AETA 3S9VA 1WL1A 4DWGA 4LUUA 2F9KF 3Q1OA 4HD1A 4FJQA 3ADZA 1FPSA 4KVDA 3TC1A 5DGMF 4QPFA 3P8LA 3AE0A 3ICKA 4LXWA 1YJ4A 3Q30A 3M00A 4H5CF 1RQIA 3RMGA 2AZLA 3N46F 3LOMA 3RBMA 5HN9A 2OPNA 2ZEVA 3LGKA 3PKOA 2PS8A 1YHKA 3KROB 1KIZA 4LA5A 1JFGA 2QISA 3DYFA 3KROA 4LA6A 3M0GA 5ILHA 4WK5A 3WCMA 2E8UA 4NFKF 3TFNA 1WKZA 4L2XF 3DYHA 4DHDA 2FORA 3NF2A 4ZQ8A 5DJRF 4DZWA 5JA0F 5ILYA 2E8XA 2ZCRA 3NPKA 5ILIA 2Q58A 1N1ZA 3WCJA 2AEKA 5IMNA 4OKMA 4Q23A 4LIXA 3LZ9A 5I1UA 1PS1A 3KRFA 4P0XA 2PS7A 3TFPA 3QKCA 5B03A 3VJ9A 2F7MF 3W7FA 3MZVA 4H5DF 4LTVA 3EGTA 5EASA 3ZOUA 2RAHA 4NUAA 5IMPA 2E8VA 4RXEA 1YYTA 2ZCQA 4LLSA 5H9DA 3V1XA 3WCCA 5IKHA 3ACXA 3WSBA 3WEFA 3G4FA 3APZA 4KFAA 2Z4WA 1JFAA 3B7LA 3M01A 4LTZA 5IVGA 3KRAB 2Z7IA 1N23A 5HNAA 2PS6A 4DEMF 4LZCA 3VJ8A 5A0IA 4GP1A 3RYWA 3WCGA 3KRAA 5CG5A 4P0VA 4N9UA 1KIYA 4LPGF 4LLTA 3CKEA 3BNXA 3N5HF 4MC8A 5A0JA 5IMIA 5DJVF 1YYUA 3KRPA 3SDUA 4KVWA 3ZMBA 3TS7A 3KRCA 1HXCA 3ZMCA 1WL3A 3OYRA 4E9UA 2E94A 1V4IA 3IPIA 5DHKA 3N5JF 5DGNF 3N1VF 3WCFA 1HX9A 4EA0A 5B02A 5B0KA 3WEIA 4RXCA 3VJBA 1DI1A 3LSNA 3Q2ZA 4XQRF 3SDVA 5HN7A 5JUZF 2PS5A 5EATA 3WCBA 2E8TA 3AQBB 4NG6A 4OGUA 5HN8A 3N1WF 4F6XA 5DHIA 2F92F 5ILJA 2I19A 4GA3A 3G4DA 5IN8A 3V66A 4LOBA 5EAUA 3KB9A 3LLWA 2F8ZF 5B0JA 2P1CA 2AZJA 4E1EA 1VG2A 4H5EF 4UMJA 4DXJA 3N45F 3NRIA 3ACYA 3DYGA 2Z52A 3KRFB 3LJIA
chains in the Genus database with same CATH topology
1V4JA 2ONHA 5E8LA 1WMWA 4EA2A 5ILKA 1YYSA 3VJAA 3ZL6A 1V4EA 1YYRA 3LMDA 1ZW5A 2DH4A 2Z4VA 4NFJF 3V1VA 3IBAA 3Q2QA 1UBWA 2E90A 5B0MA 1HM7A 3P8RA 5AYPA 3CC9A 5B01A 5E8KA 5ERMA 2ONGA 5KSXF 3PYBA 4OMHA 3CP6A 3P41A 5JV1F 1V4KA 4LZ3A 4KVYA 4N1ZF 4KPJA 4KPDA 3M02A 1HXGA 3WEKA 3WJOA 2PS4A 1UBVA 2J5CA 2E91A 1N21A 1RQJA 3KRPB 1YV5A 3OACB 2ZCSA 3ACWA 2H8OA 2Z4XA 3KRCB 3PH7A 4KWDA 5ER8A 2Z7HA 3N0FA 3S4JA 2O1OA 3OACA 2Q9YA 3WCEA 3M9UA 3SAEA 3WEHA 3ICMA 5CG6A 2Z4YA 5E8HA 4RNQA 5IL3A 3LDWA 2ZEUA 1N24A 4MC0A 4KKMA 5ILZA 3OABB 4RXAA 1YHMA 5DW7A 4PVYF 4MC3A 3WC9A 1N22A 3OABA 5B0IA 4EA1A 1RTRA 5A0KA 4JZBA 1UBYA 2ZY1A 1WY0A 3EZ3A 3N3LF 4LFVF 4RXDA 4KUXA 2VF6A 4NKEA 5IK0A 3LGZB 4LFEA 5AELA 4JVJF 3LVSA 5IKAA 4PVXF 2AELA 3WCHA 3VJEA 2FTZA 2F8CF 4DI5A 3NPRA 4KQ5A 4JZXA 3WJKA 4RYPA 1VG6A 1WL0A 3VJCA 4OMGA 3WCAA 3RYEA 2EWGA 3SDQA 3EFQA 3UCAA 3N3DA 3PDEA 5DIQF 5B00A 1YHLA 4K10A 5IK9A 3AQ0A 2E92A 3WCIA 1UBXA 4GAXA 4LZ0A 3TFVA 2F94F 2AZKA 4NFIF 4JXNA 3WSAA 2OPMA 5IM1A 3VJDA 5EROA 4XQSF 1HXAA 3KBKA 2J1OA 4GP2A 3LG5A 2Z4ZA 2E8WA 3N49F 4XQTF 4KVIA 3WE9A 2Z50A 5ILDA 3WEGA 4KK2A 3WCDA 5JV0F 4LPHF 2F89F 5AHUB 3LK5A 2OA6A 4P0WA 3QQVA 3WCLA 1N20A 2Q9ZA 3MAVA 3SDRA 3ICZA 3P5PA 4JXYA 3N6KF 4LFGA 3SDTA 3P5RA 1EZFA 4KQUA 2Q80A 2J1PA 4QXSF 3ASXA 1VG7A 3WJNA 1HM4A 3AQCB 2E4OA 3WEJA 1DGPA 2Z78A 4F6VA 1YYQA 3N0GA 1VG3A 5B0LA 5IK6A 1V4HA 5JV2F 5DJPF 4OKZA 1YQ7A 2E95A 4JYXA 5DZ2A 1VG4A 3ID0A 2OGDA 3LEEA 1N1BA 3ICNA 4KQSA 3ZCDA 4DWBA 4NKFA 4FP4A 5DGSF 2E93A 5AFXA 1WL2A 4E9ZA 3PYAA 5C05A 4F62A 3BNYA 2ZCOA 5ERNA 5IL8A 2AETA 3S9VA 1WL1A 4DWGA 4LUUA 2F9KF 3Q1OA 4HD1A 4FJQA 3ADZA 1FPSA 4KVDA 3TC1A 5DGMF 4QPFA 3P8LA 3AE0A 3ICKA 4LXWA 1YJ4A 3Q30A 3M00A 4H5CF 1RQIA 3RMGA 2AZLA 3N46F 3LOMA 3RBMA 5HN9A 2OPNA 2ZEVA 3LGKA 3PKOA 2PS8A 1YHKA 3KROB 1KIZA 4LA5A 1JFGA 2QISA 3DYFA 3KROA 4LA6A 3M0GA 5ILHA 4WK5A 3WCMA 2E8UA 4NFKF 3TFNA 1WKZA 4L2XF 3DYHA 4DHDA 2FORA 3NF2A 4ZQ8A 5DJRF 4DZWA 5JA0F 5ILYA 2E8XA 2ZCRA 3NPKA 5ILIA 2Q58A 1N1ZA 3WCJA 2AEKA 5IMNA 4OKMA 4Q23A 4LIXA 3LZ9A 5I1UA 1PS1A 3KRFA 4P0XA 2PS7A 3TFPA 3QKCA 5B03A 3VJ9A 2F7MF 3W7FA 3MZVA 4H5DF 4LTVA 3EGTA 5EASA 3ZOUA 2RAHA 4NUAA 5IMPA 2E8VA 4RXEA 1YYTA 2ZCQA 4LLSA 5H9DA 3V1XA 3WCCA 5IKHA 3ACXA 3WSBA 3WEFA 3G4FA 3APZA 4KFAA 2Z4WA 1JFAA 3B7LA 3M01A 4LTZA 5IVGA 3KRAB 2Z7IA 1N23A 5HNAA 2PS6A 4DEMF 4LZCA 3VJ8A 5A0IA 4GP1A 3RYWA 3WCGA 3KRAA 5CG5A 4P0VA 4N9UA 1KIYA 4LPGF 4LLTA 3CKEA 3BNXA 3N5HF 4MC8A 5A0JA 5IMIA 5DJVF 1YYUA 3KRPA 3SDUA 4KVWA 3ZMBA 3TS7A 3KRCA 1HXCA 3ZMCA 1WL3A 3OYRA 4E9UA 2E94A 1V4IA 3IPIA 5DHKA 3N5JF 5DGNF 3N1VF 3WCFA 1HX9A 4EA0A 5B02A 5B0KA 3WEIA 4RXCA 3VJBA 1DI1A 3LSNA 3Q2ZA 4XQRF 3SDVA 5HN7A 5JUZF 2PS5A 5EATA 3WCBA 2E8TA 3AQBB 4NG6A 4OGUA 5HN8A 3N1WF 4F6XA 5DHIA 2F92F 5ILJA 2I19A 4GA3A 3G4DA 5IN8A 3V66A 4LOBA 5EAUA 3KB9A 3LLWA 2F8ZF 5B0JA 2P1CA 2AZJA 4E1EA 1VG2A 4H5EF 4UMJA 4DXJA 3N45F 3NRIA 3ACYA 3DYGA 2Z52A 3KRFB 3LJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1V4J A;  2ONH A;  5E8L A;  1WMW A;  4EA2 A;  5ILK A;  1YYS A;  3VJA A;  3ZL6 A;  1V4E A;  1YYR A;  3LMD A;  1ZW5 A;  2DH4 A;  2Z4V A;  4NFJ F;  3V1V A;  3IBA A;  3Q2Q A;  1UBW A;  2E90 A;  5B0M A;  1HM7 A;  3P8R A;  5AYP A;  3CC9 A;  5B01 A;  5E8K A;  5ERM A;  2ONG A;  5KSX F;  3PYB A;  4OMH A;  3CP6 A;  3P41 A;  5JV1 F;  1V4K A;  4LZ3 A;  4KVY A;  4N1Z F;  4KPJ A;  4KPD A;  3M02 A;  1HXG A;  3WEK A;  3WJO A;  2PS4 A;  1UBV A;  2J5C A;  2E91 A;  1N21 A;  1RQJ A;  3KRP B;  1YV5 A;  3OAC B;  2ZCS A;  3ACW A;  2H8O A;  2Z4X A;  3KRC B;  3PH7 A;  4KWD A;  5ER8 A;  2Z7H A;  3N0F A;  3S4J A;  2O1O A;  3OAC A;  2Q9Y A;  3WCE A;  3M9U A;  3SAE A;  3WEH A;  3ICM A;  5CG6 A;  2Z4Y A;  5E8H A;  4RNQ A;  5IL3 A;  3LDW A;  2ZEU A;  1N24 A;  4MC0 A;  4KKM A;  5ILZ A;  3OAB B;  4RXA A;  1YHM A;  5DW7 A;  4PVY F;  4MC3 A;  3WC9 A;  1N22 A;  3OAB A;  5B0I A;  4EA1 A;  1RTR A;  5A0K A;  4JZB A;  1UBY A;  2ZY1 A;  1WY0 A;  3EZ3 A;  3N3L F;  4LFV F;  4RXD A;  4KUX A;  2VF6 A;  4NKE A;  5IK0 A;  3LGZ B;  4LFE A;  5AEL A;  4JVJ F;  3LVS A;  5IKA A;  4PVX F;  2AEL A;  3WCH A;  3VJE A;  2FTZ A;  2F8C F;  4DI5 A;  3NPR A;  4KQ5 A;  4JZX A;  3WJK A;  4RYP A;  1VG6 A;  1WL0 A;  3VJC A;  4OMG A;  3WCA A;  3RYE A;  2EWG A;  3SDQ A;  3EFQ A;  3UCA A;  3N3D A;  3PDE A;  5DIQ F;  5B00 A;  1YHL A;  4K10 A;  5IK9 A;  3AQ0 A;  2E92 A;  3WCI A;  1UBX A;  4GAX A;  4LZ0 A;  3TFV A;  2F94 F;  2AZK A;  4NFI F;  4JXN A;  3WSA A;  2OPM A;  5IM1 A;  3VJD A;  5ERO A;  4XQS F;  1HXA A;  3KBK A;  2J1O A;  4GP2 A;  3LG5 A;  2Z4Z A;  2E8W A;  3N49 F;  4XQT F;  4KVI A;  3WE9 A;  2Z50 A;  5ILD A;  3WEG A;  4KK2 A;  3WCD A;  5JV0 F;  4LPH F;  2F89 F;  5AHU B;  3LK5 A;  2OA6 A;  4P0W A;  3QQV A;  3WCL A;  1N20 A;  2Q9Z A;  3MAV A;  3SDR A;  3ICZ A;  3P5P A;  4JXY A;  3N6K F;  4LFG A;  3SDT A;  3P5R A;  1EZF A;  4KQU A;  2Q80 A;  2J1P A;  4QXS F;  3ASX A;  1VG7 A;  3WJN A;  1HM4 A;  3AQC B;  2E4O A;  3WEJ A;  1DGP A;  2Z78 A;  4F6V A;  1YYQ A;  3N0G A;  1VG3 A;  5B0L A;  5IK6 A;  1V4H A;  5JV2 F;  5DJP F;  4OKZ A;  1YQ7 A;  2E95 A;  4JYX A;  5DZ2 A;  1VG4 A;  3ID0 A;  2OGD A;  3LEE A;  1N1B A;  3ICN A;  4KQS A;  3ZCD A;  4DWB A;  4NKF A;  4FP4 A;  5DGS F;  2E93 A;  5AFX A;  1WL2 A;  4E9Z A;  3PYA A;  5C05 A;  4F62 A;  3BNY A;  2ZCO A;  5ERN A;  5IL8 A;  2AET A;  3S9V A;  1WL1 A;  4DWG A;  4LUU A;  2F9K F;  3Q1O A;  4HD1 A;  4FJQ A;  3ADZ A;  1FPS A;  4KVD A;  3TC1 A;  5DGM F;  4QPF A;  3P8L A;  3AE0 A;  3ICK A;  4LXW A;  1YJ4 A;  3Q30 A;  3M00 A;  4H5C F;  1RQI A;  3RMG A;  2AZL A;  3N46 F;  3LOM A;  3RBM A;  5HN9 A;  2OPN A;  2ZEV A;  3LGK A;  3PKO A;  2PS8 A;  1YHK A;  3KRO B;  1KIZ A;  4LA5 A;  1JFG A;  2QIS A;  3DYF A;  3KRO A;  4LA6 A;  3M0G A;  5ILH A;  4WK5 A;  3WCM A;  2E8U A;  4NFK F;  3TFN A;  1WKZ A;  4L2X F;  3DYH A;  4DHD A;  2FOR A;  3NF2 A;  4ZQ8 A;  5DJR F;  4DZW A;  5JA0 F;  5ILY A;  2E8X A;  2ZCR A;  3NPK A;  5ILI A;  2Q58 A;  1N1Z A;  3WCJ A;  2AEK A;  5IMN A;  4OKM A;  4Q23 A;  4LIX A;  3LZ9 A;  5I1U A;  1PS1 A;  3KRF A;  4P0X A;  2PS7 A;  3TFP A;  3QKC A;  5B03 A;  3VJ9 A;  2F7M F;  3W7F A;  3MZV A;  4H5D F;  4LTV A;  3EGT A;  5EAS A;  3ZOU A;  2RAH A;  4NUA A;  5IMP A;  2E8V A;  4RXE A;  1YYT A;  2ZCQ A;  4LLS A;  5H9D A;  3V1X A;  3WCC A;  5IKH A;  3ACX A;  3WSB A;  3WEF A;  3G4F A;  3APZ A;  4KFA A;  2Z4W A;  1JFA A;  3B7L A;  3M01 A;  4LTZ A;  5IVG A;  3KRA B;  2Z7I A;  1N23 A;  5HNA A;  2PS6 A;  4DEM F;  4LZC A;  3VJ8 A;  5A0I A;  4GP1 A;  3RYW A;  3WCG A;  3KRA A;  5CG5 A;  4P0V A;  4N9U A;  1KIY A;  4LPG F;  4LLT A;  3CKE A;  3BNX A;  3N5H F;  4MC8 A;  5A0J A;  5IMI A;  5DJV F;  1YYU A;  3KRP A;  3SDU A;  4KVW A;  3ZMB A;  3TS7 A;  3KRC A;  1HXC A;  3ZMC A;  1WL3 A;  3OYR A;  4E9U A;  2E94 A;  1V4I A;  3IPI A;  5DHK A;  3N5J F;  5DGN F;  3N1V F;  3WCF A;  1HX9 A;  4EA0 A;  5B02 A;  5B0K A;  3WEI A;  4RXC A;  3VJB A;  1DI1 A;  3LSN A;  3Q2Z A;  4XQR F;  3SDV A;  5HN7 A;  5JUZ F;  2PS5 A;  5EAT A;  3WCB A;  2E8T A;  3AQB B;  4NG6 A;  4OGU A;  5HN8 A;  3N1W F;  4F6X A;  5DHI A;  2F92 F;  5ILJ A;  2I19 A;  4GA3 A;  3G4D A;  5IN8 A;  3V66 A;  4LOB A;  5EAU A;  3KB9 A;  3LLW A;  2F8Z F;  5B0J A;  2P1C A;  2AZJ A;  4E1E A;  1VG2 A;  4H5E F;  4UMJ A;  4DXJ A;  3N45 F;  3NRI A;  3ACY A;  3DYG A;  2Z52 A;  3KRF B;  3LJI A; 
#chains in the Genus database with same CATH topology
 1V4J A;  2ONH A;  5E8L A;  1WMW A;  4EA2 A;  5ILK A;  1YYS A;  3VJA A;  3ZL6 A;  1V4E A;  1YYR A;  3LMD A;  1ZW5 A;  2DH4 A;  2Z4V A;  4NFJ F;  3V1V A;  3IBA A;  3Q2Q A;  1UBW A;  2E90 A;  5B0M A;  1HM7 A;  3P8R A;  5AYP A;  3CC9 A;  5B01 A;  5E8K A;  5ERM A;  2ONG A;  5KSX F;  3PYB A;  4OMH A;  3CP6 A;  3P41 A;  5JV1 F;  1V4K A;  4LZ3 A;  4KVY A;  4N1Z F;  4KPJ A;  4KPD A;  3M02 A;  1HXG A;  3WEK A;  3WJO A;  2PS4 A;  1UBV A;  2J5C A;  2E91 A;  1N21 A;  1RQJ A;  3KRP B;  1YV5 A;  3OAC B;  2ZCS A;  3ACW A;  2H8O A;  2Z4X A;  3KRC B;  3PH7 A;  4KWD A;  5ER8 A;  2Z7H A;  3N0F A;  3S4J A;  2O1O A;  3OAC A;  2Q9Y A;  3WCE A;  3M9U A;  3SAE A;  3WEH A;  3ICM A;  5CG6 A;  2Z4Y A;  5E8H A;  4RNQ A;  5IL3 A;  3LDW A;  2ZEU A;  1N24 A;  4MC0 A;  4KKM A;  5ILZ A;  3OAB B;  4RXA A;  1YHM A;  5DW7 A;  4PVY F;  4MC3 A;  3WC9 A;  1N22 A;  3OAB A;  5B0I A;  4EA1 A;  1RTR A;  5A0K A;  4JZB A;  1UBY A;  2ZY1 A;  1WY0 A;  3EZ3 A;  3N3L F;  4LFV F;  4RXD A;  4KUX A;  2VF6 A;  4NKE A;  5IK0 A;  3LGZ B;  4LFE A;  5AEL A;  4JVJ F;  3LVS A;  5IKA A;  4PVX F;  2AEL A;  3WCH A;  3VJE A;  2FTZ A;  2F8C F;  4DI5 A;  3NPR A;  4KQ5 A;  4JZX A;  3WJK A;  4RYP A;  1VG6 A;  1WL0 A;  3VJC A;  4OMG A;  3WCA A;  3RYE A;  2EWG A;  3SDQ A;  3EFQ A;  3UCA A;  3N3D A;  3PDE A;  5DIQ F;  5B00 A;  1YHL A;  4K10 A;  5IK9 A;  3AQ0 A;  2E92 A;  3WCI A;  1UBX A;  4GAX A;  4LZ0 A;  3TFV A;  2F94 F;  2AZK A;  4NFI F;  4JXN A;  3WSA A;  2OPM A;  5IM1 A;  3VJD A;  5ERO A;  4XQS F;  1HXA A;  3KBK A;  2J1O A;  4GP2 A;  3LG5 A;  2Z4Z A;  2E8W A;  3N49 F;  4XQT F;  4KVI A;  3WE9 A;  2Z50 A;  5ILD A;  3WEG A;  4KK2 A;  3WCD A;  5JV0 F;  4LPH F;  2F89 F;  5AHU B;  3LK5 A;  2OA6 A;  4P0W A;  3QQV A;  3WCL A;  1N20 A;  2Q9Z A;  3MAV A;  3SDR A;  3ICZ A;  3P5P A;  4JXY A;  3N6K F;  4LFG A;  3SDT A;  3P5R A;  1EZF A;  4KQU A;  2Q80 A;  2J1P A;  4QXS F;  3ASX A;  1VG7 A;  3WJN A;  1HM4 A;  3AQC B;  2E4O A;  3WEJ A;  1DGP A;  2Z78 A;  4F6V A;  1YYQ A;  3N0G A;  1VG3 A;  5B0L A;  5IK6 A;  1V4H A;  5JV2 F;  5DJP F;  4OKZ A;  1YQ7 A;  2E95 A;  4JYX A;  5DZ2 A;  1VG4 A;  3ID0 A;  2OGD A;  3LEE A;  1N1B A;  3ICN A;  4KQS A;  3ZCD A;  4DWB A;  4NKF A;  4FP4 A;  5DGS F;  2E93 A;  5AFX A;  1WL2 A;  4E9Z A;  3PYA A;  5C05 A;  4F62 A;  3BNY A;  2ZCO A;  5ERN A;  5IL8 A;  2AET A;  3S9V A;  1WL1 A;  4DWG A;  4LUU A;  2F9K F;  3Q1O A;  4HD1 A;  4FJQ A;  3ADZ A;  1FPS A;  4KVD A;  3TC1 A;  5DGM F;  4QPF A;  3P8L A;  3AE0 A;  3ICK A;  4LXW A;  1YJ4 A;  3Q30 A;  3M00 A;  4H5C F;  1RQI A;  3RMG A;  2AZL A;  3N46 F;  3LOM A;  3RBM A;  5HN9 A;  2OPN A;  2ZEV A;  3LGK A;  3PKO A;  2PS8 A;  1YHK A;  3KRO B;  1KIZ A;  4LA5 A;  1JFG A;  2QIS A;  3DYF A;  3KRO A;  4LA6 A;  3M0G A;  5ILH A;  4WK5 A;  3WCM A;  2E8U A;  4NFK F;  3TFN A;  1WKZ A;  4L2X F;  3DYH A;  4DHD A;  2FOR A;  3NF2 A;  4ZQ8 A;  5DJR F;  4DZW A;  5JA0 F;  5ILY A;  2E8X A;  2ZCR A;  3NPK A;  5ILI A;  2Q58 A;  1N1Z A;  3WCJ A;  2AEK A;  5IMN A;  4OKM A;  4Q23 A;  4LIX A;  3LZ9 A;  5I1U A;  1PS1 A;  3KRF A;  4P0X A;  2PS7 A;  3TFP A;  3QKC A;  5B03 A;  3VJ9 A;  2F7M F;  3W7F A;  3MZV A;  4H5D F;  4LTV A;  3EGT A;  5EAS A;  3ZOU A;  2RAH A;  4NUA A;  5IMP A;  2E8V A;  4RXE A;  1YYT A;  2ZCQ A;  4LLS A;  5H9D A;  3V1X A;  3WCC A;  5IKH A;  3ACX A;  3WSB A;  3WEF A;  3G4F A;  3APZ A;  4KFA A;  2Z4W A;  1JFA A;  3B7L A;  3M01 A;  4LTZ A;  5IVG A;  3KRA B;  2Z7I A;  1N23 A;  5HNA A;  2PS6 A;  4DEM F;  4LZC A;  3VJ8 A;  5A0I A;  4GP1 A;  3RYW A;  3WCG A;  3KRA A;  5CG5 A;  4P0V A;  4N9U A;  1KIY A;  4LPG F;  4LLT A;  3CKE A;  3BNX A;  3N5H F;  4MC8 A;  5A0J A;  5IMI A;  5DJV F;  1YYU A;  3KRP A;  3SDU A;  4KVW A;  3ZMB A;  3TS7 A;  3KRC A;  1HXC A;  3ZMC A;  1WL3 A;  3OYR A;  4E9U A;  2E94 A;  1V4I A;  3IPI A;  5DHK A;  3N5J F;  5DGN F;  3N1V F;  3WCF A;  1HX9 A;  4EA0 A;  5B02 A;  5B0K A;  3WEI A;  4RXC A;  3VJB A;  1DI1 A;  3LSN A;  3Q2Z A;  4XQR F;  3SDV A;  5HN7 A;  5JUZ F;  2PS5 A;  5EAT A;  3WCB A;  2E8T A;  3AQB B;  4NG6 A;  4OGU A;  5HN8 A;  3N1W F;  4F6X A;  5DHI A;  2F92 F;  5ILJ A;  2I19 A;  4GA3 A;  3G4D A;  5IN8 A;  3V66 A;  4LOB A;  5EAU A;  3KB9 A;  3LLW A;  2F8Z F;  5B0J A;  2P1C A;  2AZJ A;  4E1E A;  1VG2 A;  4H5E F;  4UMJ A;  4DXJ A;  3N45 F;  3NRI A;  3ACY A;  3DYG A;  2Z52 A;  3KRF B;  3LJI A; 
#chains in the Genus database with same CATH homology
 1V4J A;  2ONH A;  5E8L A;  1WMW A;  4EA2 A;  5ILK A;  1YYS A;  3VJA A;  3ZL6 A;  1V4E A;  1YYR A;  3LMD A;  1ZW5 A;  2DH4 A;  2Z4V A;  4NFJ F;  3V1V A;  3IBA A;  3Q2Q A;  1UBW A;  2E90 A;  5B0M A;  1HM7 A;  3P8R A;  5AYP A;  3CC9 A;  5B01 A;  5E8K A;  5ERM A;  2ONG A;  5KSX F;  3PYB A;  4OMH A;  3CP6 A;  3P41 A;  5JV1 F;  1V4K A;  4LZ3 A;  4KVY A;  4N1Z F;  4KPJ A;  4KPD A;  3M02 A;  1HXG A;  3WEK A;  3WJO A;  2PS4 A;  1UBV A;  2J5C A;  2E91 A;  1N21 A;  1RQJ A;  3KRP B;  1YV5 A;  3OAC B;  2ZCS A;  3ACW A;  2H8O A;  2Z4X A;  3KRC B;  3PH7 A;  4KWD A;  5ER8 A;  2Z7H A;  3N0F A;  3S4J A;  2O1O A;  3OAC A;  2Q9Y A;  3WCE A;  3M9U A;  3SAE A;  3WEH A;  3ICM A;  5CG6 A;  2Z4Y A;  5E8H A;  4RNQ A;  5IL3 A;  3LDW A;  2ZEU A;  1N24 A;  4MC0 A;  4KKM A;  5ILZ A;  3OAB B;  4RXA A;  1YHM A;  5DW7 A;  4PVY F;  4MC3 A;  3WC9 A;  1N22 A;  3OAB A;  5B0I A;  4EA1 A;  1RTR A;  5A0K A;  4JZB A;  1UBY A;  2ZY1 A;  1WY0 A;  3EZ3 A;  3N3L F;  4LFV F;  4RXD A;  4KUX A;  2VF6 A;  4NKE A;  5IK0 A;  3LGZ B;  4LFE A;  5AEL A;  4JVJ F;  3LVS A;  5IKA A;  4PVX F;  2AEL A;  3WCH A;  3VJE A;  2FTZ A;  2F8C F;  4DI5 A;  3NPR A;  4KQ5 A;  4JZX A;  3WJK A;  4RYP A;  1VG6 A;  1WL0 A;  3VJC A;  4OMG A;  3WCA A;  3RYE A;  2EWG A;  3SDQ A;  3EFQ A;  3UCA A;  3N3D A;  3PDE A;  5DIQ F;  5B00 A;  1YHL A;  4K10 A;  5IK9 A;  3AQ0 A;  2E92 A;  3WCI A;  1UBX A;  4GAX A;  4LZ0 A;  3TFV A;  2F94 F;  2AZK A;  4NFI F;  4JXN A;  3WSA A;  2OPM A;  5IM1 A;  3VJD A;  5ERO A;  4XQS F;  1HXA A;  3KBK A;  2J1O A;  4GP2 A;  3LG5 A;  2Z4Z A;  2E8W A;  3N49 F;  4XQT F;  4KVI A;  3WE9 A;  2Z50 A;  5ILD A;  3WEG A;  4KK2 A;  3WCD A;  5JV0 F;  4LPH F;  2F89 F;  5AHU B;  3LK5 A;  2OA6 A;  4P0W A;  3QQV A;  3WCL A;  1N20 A;  2Q9Z A;  3MAV A;  3SDR A;  3ICZ A;  3P5P A;  4JXY A;  3N6K F;  4LFG A;  3SDT A;  3P5R A;  1EZF A;  4KQU A;  2Q80 A;  2J1P A;  4QXS F;  3ASX A;  1VG7 A;  3WJN A;  1HM4 A;  3AQC B;  2E4O A;  3WEJ A;  1DGP A;  2Z78 A;  4F6V A;  1YYQ A;  3N0G A;  1VG3 A;  5B0L A;  5IK6 A;  1V4H A;  5JV2 F;  5DJP F;  4OKZ A;  1YQ7 A;  2E95 A;  4JYX A;  5DZ2 A;  1VG4 A;  3ID0 A;  2OGD A;  3LEE A;  1N1B A;  3ICN A;  4KQS A;  3ZCD A;  4DWB A;  4NKF A;  4FP4 A;  5DGS F;  2E93 A;  5AFX A;  1WL2 A;  4E9Z A;  3PYA A;  5C05 A;  4F62 A;  3BNY A;  2ZCO A;  5ERN A;  5IL8 A;  2AET A;  3S9V A;  1WL1 A;  4DWG A;  4LUU A;  2F9K F;  3Q1O A;  4HD1 A;  4FJQ A;  3ADZ A;  1FPS A;  4KVD A;  3TC1 A;  5DGM F;  4QPF A;  3P8L A;  3AE0 A;  3ICK A;  4LXW A;  1YJ4 A;  3Q30 A;  3M00 A;  4H5C F;  1RQI A;  3RMG A;  2AZL A;  3N46 F;  3LOM A;  3RBM A;  5HN9 A;  2OPN A;  2ZEV A;  3LGK A;  3PKO A;  2PS8 A;  1YHK A;  3KRO B;  1KIZ A;  4LA5 A;  1JFG A;  2QIS A;  3DYF A;  3KRO A;  4LA6 A;  3M0G A;  5ILH A;  4WK5 A;  3WCM A;  2E8U A;  4NFK F;  3TFN A;  1WKZ A;  4L2X F;  3DYH A;  4DHD A;  2FOR A;  3NF2 A;  4ZQ8 A;  5DJR F;  4DZW A;  5JA0 F;  5ILY A;  2E8X A;  2ZCR A;  3NPK A;  5ILI A;  2Q58 A;  1N1Z A;  3WCJ A;  2AEK A;  5IMN A;  4OKM A;  4Q23 A;  4LIX A;  3LZ9 A;  5I1U A;  1PS1 A;  3KRF A;  4P0X A;  2PS7 A;  3TFP A;  3QKC A;  5B03 A;  3VJ9 A;  2F7M F;  3W7F A;  3MZV A;  4H5D F;  4LTV A;  3EGT A;  5EAS A;  3ZOU A;  2RAH A;  4NUA A;  5IMP A;  2E8V A;  4RXE A;  1YYT A;  2ZCQ A;  4LLS A;  5H9D A;  3V1X A;  3WCC A;  5IKH A;  3ACX A;  3WSB A;  3WEF A;  3G4F A;  3APZ A;  4KFA A;  2Z4W A;  1JFA A;  3B7L A;  3M01 A;  4LTZ A;  5IVG A;  3KRA B;  2Z7I A;  1N23 A;  5HNA A;  2PS6 A;  4DEM F;  4LZC A;  3VJ8 A;  5A0I A;  4GP1 A;  3RYW A;  3WCG A;  3KRA A;  5CG5 A;  4P0V A;  4N9U A;  1KIY A;  4LPG F;  4LLT A;  3CKE A;  3BNX A;  3N5H F;  4MC8 A;  5A0J A;  5IMI A;  5DJV F;  1YYU A;  3KRP A;  3SDU A;  4KVW A;  3ZMB A;  3TS7 A;  3KRC A;  1HXC A;  3ZMC A;  1WL3 A;  3OYR A;  4E9U A;  2E94 A;  1V4I A;  3IPI A;  5DHK A;  3N5J F;  5DGN F;  3N1V F;  3WCF A;  1HX9 A;  4EA0 A;  5B02 A;  5B0K A;  3WEI A;  4RXC A;  3VJB A;  1DI1 A;  3LSN A;  3Q2Z A;  4XQR F;  3SDV A;  5HN7 A;  5JUZ F;  2PS5 A;  5EAT A;  3WCB A;  2E8T A;  3AQB B;  4NG6 A;  4OGU A;  5HN8 A;  3N1W F;  4F6X A;  5DHI A;  2F92 F;  5ILJ A;  2I19 A;  4GA3 A;  3G4D A;  5IN8 A;  3V66 A;  4LOB A;  5EAU A;  3KB9 A;  3LLW A;  2F8Z F;  5B0J A;  2P1C A;  2AZJ A;  4E1E A;  1VG2 A;  4H5E F;  4UMJ A;  4DXJ A;  3N45 F;  3NRI A;  3ACY A;  3DYG A;  2Z52 A;  3KRF B;  3LJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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