3TFNA

Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1183
Total Genus 117
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
117
sequence length
284
structure length
284
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
molecule keywords Dehydrosqualene synthase
total genus 117
structure length 284
sequence length 284
ec nomenclature ec 2.5.1.96: 4,4'-diapophytoene synthase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3tfnA00
3NF2A 3ZL6A 3N5JF 3P8RA 5B0IA 1YYSA 4F6VA 3EGTA 4E9ZA 1EZFA 2E8VA 3ICKA 2ONGA 2AELA 2Z78A 1N1ZA 3RBMA 3VJBA 3SDQA 4JZXA 2E8WA 3WC9A 4KQUA 1HX9A 5DGMF 3WEHA 2O1OA 3AQ0A 3AQCB 3M00A 2Z52A 4DHDA 4GA3A 3OACA 2ZCQA 1JFAA 5DGSF 5A0JA 4XQSF 1UBWA 1VG6A 3PKOA 4N9UA 5ILYA 1UBVA 5C05A 2QISA 5ILZA 5IM1A 3ASXA 3N49F 4NUAA 3MZVA 1YHKA 4P0WA 5IKHA 3OACB 3ACWA 3VJEA 4LPHF 2Q58A 4DXJA 5JUZF 1VG3A 3SDUA 3SDVA 3BNYA 3LMDA 5E8HA 4RXCA 3V66A 5IMPA 3VJCA 3S9VA 4DWBA 3WEGA 4K10A 5DW7A 3CKEA 5ILIA 4WK5A 3WCMA 4E9UA 4PVYF 2AETA 4EA1A 5E8LA 3KBKA 5B0KA 3RYEA 3ADZA 2J1PA 3N5HF 1KIZA 2PS6A 4P0VA 4UMJA 4DI5A 3SDTA 3VJAA 5ILHA 1RTRA 1WKZA 2ZEUA 3WCLA 3VJDA 2I19A 5IL3A 2Q9YA 2FTZA 1HM4A 4KKMA 1WL1A 5JV2F 3WEFA 4LLTA 4E1EA 3WCAA 3DYGA 2RAHA 1RQIA 1HXCA 3P8LA 3WCGA 1WL0A 2Z4VA 2PS8A 3KRCA 4F62A 5AFXA 3KRAB 1N22A 5DJVF 3P5PA 3ICNA 4JXNA 3DYFA 4DWGA 1YHLA 3G4FA 5JA0F 4ZQ8A 3G4DA 4LZ0A 3LZ9A 3KRCB 5AHUB 3WJOA 2PS4A 4H5EF 2Q9ZA 3APZA 4L2XF 3WEKA 4QXSF 1YYTA 1VG4A 3MAVA 2E4OA 1YYQA 5EROA 3ACXA 2ZY1A 3WCEA 5B0LA 3WCJA 2E95A 3LLWA 3V1VA 4EA0A 4H5CF 3WJNA 1YQ7A 4PVXF 5AYPA 2EWGA 4OGUA 3N45F 1WL2A 5B0MA 3LK5A 4FP4A 3RYWA 1YJ4A 4RXEA 1FPSA 1UBXA 1YYRA 4KK2A 4GAXA 1YHMA 3LJIA 3TC1A 3WCCA 3PH7A 2Z4XA 2F92F 3LEEA 4LOBA 1DI1A 1N24A 4KPDA 5HN7A 5IK9A 3P41A 3WEJA 4KVIA 3TS7A 5HN9A 1V4JA 4NKFA 4KQSA 3Q2QA 3WE9A 2OPMA 1WMWA 2E94A 1KIYA 3ZMBA 3SDRA 5IL8A 3QQVA 3B7LA 2E8XA 1N23A 5E8KA 3LG5A 4DEMF 3ZCDA 3KROA 2E8TA 5B02A 2OA6A 5JV1F 5KSXF 3LSNA 2Z4ZA 3IBAA 4KQ5A 3LGKA 3OYRA 2H8OA 4EA2A 1WL3A 3VJ9A 2F94F 3N3DA 1N1BA 2J5CA 4OKZA 3LVSA 5CG6A 4HD1A 3KRFA 3KROB 4LTVA 3TFPA 5B0JA 1UBYA 4JXYA 5EATA 2J1OA 1YYUA 5IMNA 5HN8A 2E92A 3DYHA 3AE0A 2E93A 4XQRF 3BNXA 4KVDA 3WSBA 4JZBA 4KPJA 3KRFB 3LDWA 4DZWA 3WJKA 4KUXA 4NG6A 5DZ2A 5IKAA 3N46F 5EAUA 5B03A 3M9UA 3CC9A 2Q80A 2Z4WA 4LFGA 5DHKA 5ILDA 1PS1A 3WCFA 4QPFA 5IK6A 2AZJA 1V4IA 4Q23A 2ZCSA 3TFNA 3WCHA 3NRIA 4LFVF 5DJPF 4GP1A 2F8ZF 5IVGA 3VJ8A 5AELA 3OABA 1N21A 3EZ3A 3S4JA 4N1ZF 3LOMA 2OGDA 3V1XA 5ILJA 5B00A 4NFJF 3WEIA 3ZOUA 4LXWA 4KFAA 2E91A 3ACYA 3PYBA 4LZ3A 1V4HA 4MC3A 1HXAA 2ONHA 1VG7A 3OABB 3IPIA 2F7MF 1DGPA 2F8CF 4NKEA 3ZMCA 3Q2ZA 2PS5A 4H5DF 4XQTF 3TFVA 2F9KF 3WCIA 3P5RA 4LFEA 3N0GA 1VG2A 4RYPA 3LGZB 1RQJA 4LA6A 4MC0A 2AZKA 4KWDA 5HNAA 4RNQA 1V4KA 4LA5A 1V4EA 1JFGA 3ICZA 3M01A 3N0FA 2F89F 3ID0A 3NPRA 3PYAA 4RXDA 5ILKA 3UCAA 5EASA 5JV0F 3N1WF 2Z7IA 2Z7HA 5ERMA 2PS7A 3M0GA 4FJQA 5DJRF 3N3LF 3CP6A 3Q1OA 3RMGA 4GP2A 4LUUA 4OMGA 3M02A 4KVWA 5H9DA 3PDEA 2FORA 4KVYA 3ICMA 1N20A 3WCBA 2ZEVA 3KRPA 1WY0A 3QKCA 3SAEA 1YV5A 2P1CA 3WSAA 3AQBB 3WCDA 5A0IA 2DH4A 3N6KF 5DIQF 2VF6A 3Q30A 2Z50A 2E90A 4OMHA 2Z4YA 2AEKA 3KRPB 1ZW5A 4NFKF 5DHIA 1HM7A 5IN8A 5I1UA 5ER8A 5B01A 4LLSA 4LPGF 3KB9A 5IMIA 3EFQA 2OPNA 3N1VF 4P0XA 2ZCRA 4LIXA 5A0KA 4JYXA 5ERNA 2AZLA 1HXGA 5CG5A 3KRAA 4JVJF 4LZCA 2E8UA 3NPKA 4LTZA 4RXAA 3W7FA 4NFIF 2ZCOA 4OKMA 5IK0A 4MC8A 5DGNF 4F6XA
chains in the Genus database with same CATH superfamily
3NF2A 3ZL6A 3N5JF 3P8RA 5B0IA 1YYSA 4F6VA 3EGTA 4E9ZA 1EZFA 2E8VA 3ICKA 2ONGA 2AELA 2Z78A 1N1ZA 3RBMA 3VJBA 3SDQA 4JZXA 2E8WA 3WC9A 4KQUA 1HX9A 5DGMF 3WEHA 2O1OA 3AQ0A 3AQCB 3M00A 2Z52A 4DHDA 4GA3A 3OACA 2ZCQA 1JFAA 5DGSF 5A0JA 4XQSF 1UBWA 1VG6A 3PKOA 4N9UA 5ILYA 1UBVA 5C05A 2QISA 5ILZA 5IM1A 3ASXA 3N49F 4NUAA 3MZVA 1YHKA 4P0WA 5IKHA 3OACB 3ACWA 3VJEA 4LPHF 2Q58A 4DXJA 5JUZF 1VG3A 3SDUA 3SDVA 3BNYA 3LMDA 5E8HA 4RXCA 3V66A 5IMPA 3VJCA 3S9VA 4DWBA 3WEGA 4K10A 5DW7A 3CKEA 5ILIA 4WK5A 3WCMA 4E9UA 4PVYF 2AETA 4EA1A 5E8LA 3KBKA 5B0KA 3RYEA 3ADZA 2J1PA 3N5HF 1KIZA 2PS6A 4P0VA 4UMJA 4DI5A 3SDTA 3VJAA 5ILHA 1RTRA 1WKZA 2ZEUA 3WCLA 3VJDA 2I19A 5IL3A 2Q9YA 2FTZA 1HM4A 4KKMA 1WL1A 5JV2F 3WEFA 4LLTA 4E1EA 3WCAA 3DYGA 2RAHA 1RQIA 1HXCA 3P8LA 3WCGA 1WL0A 2Z4VA 2PS8A 3KRCA 4F62A 5AFXA 3KRAB 1N22A 5DJVF 3P5PA 3ICNA 4JXNA 3DYFA 4DWGA 1YHLA 3G4FA 5JA0F 4ZQ8A 3G4DA 4LZ0A 3LZ9A 3KRCB 5AHUB 3WJOA 2PS4A 4H5EF 2Q9ZA 3APZA 4L2XF 3WEKA 4QXSF 1YYTA 1VG4A 3MAVA 2E4OA 1YYQA 5EROA 3ACXA 2ZY1A 3WCEA 5B0LA 3WCJA 2E95A 3LLWA 3V1VA 4EA0A 4H5CF 3WJNA 1YQ7A 4PVXF 5AYPA 2EWGA 4OGUA 3N45F 1WL2A 5B0MA 3LK5A 4FP4A 3RYWA 1YJ4A 4RXEA 1FPSA 1UBXA 1YYRA 4KK2A 4GAXA 1YHMA 3LJIA 3TC1A 3WCCA 3PH7A 2Z4XA 2F92F 3LEEA 4LOBA 1DI1A 1N24A 4KPDA 5HN7A 5IK9A 3P41A 3WEJA 4KVIA 3TS7A 5HN9A 1V4JA 4NKFA 4KQSA 3Q2QA 3WE9A 2OPMA 1WMWA 2E94A 1KIYA 3ZMBA 3SDRA 5IL8A 3QQVA 3B7LA 2E8XA 1N23A 5E8KA 3LG5A 4DEMF 3ZCDA 3KROA 2E8TA 5B02A 2OA6A 5JV1F 5KSXF 3LSNA 2Z4ZA 3IBAA 4KQ5A 3LGKA 3OYRA 2H8OA 4EA2A 1WL3A 3VJ9A 2F94F 3N3DA 1N1BA 2J5CA 4OKZA 3LVSA 5CG6A 4HD1A 3KRFA 3KROB 4LTVA 3TFPA 5B0JA 1UBYA 4JXYA 5EATA 2J1OA 1YYUA 5IMNA 5HN8A 2E92A 3DYHA 3AE0A 2E93A 4XQRF 3BNXA 4KVDA 3WSBA 4JZBA 4KPJA 3KRFB 3LDWA 4DZWA 3WJKA 4KUXA 4NG6A 5DZ2A 5IKAA 3N46F 5EAUA 5B03A 3M9UA 3CC9A 2Q80A 2Z4WA 4LFGA 5DHKA 5ILDA 1PS1A 3WCFA 4QPFA 5IK6A 2AZJA 1V4IA 4Q23A 2ZCSA 3TFNA 3WCHA 3NRIA 4LFVF 5DJPF 4GP1A 2F8ZF 5IVGA 3VJ8A 5AELA 3OABA 1N21A 3EZ3A 3S4JA 4N1ZF 3LOMA 2OGDA 3V1XA 5ILJA 5B00A 4NFJF 3WEIA 3ZOUA 4LXWA 4KFAA 2E91A 3ACYA 3PYBA 4LZ3A 1V4HA 4MC3A 1HXAA 2ONHA 1VG7A 3OABB 3IPIA 2F7MF 1DGPA 2F8CF 4NKEA 3ZMCA 3Q2ZA 2PS5A 4H5DF 4XQTF 3TFVA 2F9KF 3WCIA 3P5RA 4LFEA 3N0GA 1VG2A 4RYPA 3LGZB 1RQJA 4LA6A 4MC0A 2AZKA 4KWDA 5HNAA 4RNQA 1V4KA 4LA5A 1V4EA 1JFGA 3ICZA 3M01A 3N0FA 2F89F 3ID0A 3NPRA 3PYAA 4RXDA 5ILKA 3UCAA 5EASA 5JV0F 3N1WF 2Z7IA 2Z7HA 5ERMA 2PS7A 3M0GA 4FJQA 5DJRF 3N3LF 3CP6A 3Q1OA 3RMGA 4GP2A 4LUUA 4OMGA 3M02A 4KVWA 5H9DA 3PDEA 2FORA 4KVYA 3ICMA 1N20A 3WCBA 2ZEVA 3KRPA 1WY0A 3QKCA 3SAEA 1YV5A 2P1CA 3WSAA 3AQBB 3WCDA 5A0IA 2DH4A 3N6KF 5DIQF 2VF6A 3Q30A 2Z50A 2E90A 4OMHA 2Z4YA 2AEKA 3KRPB 1ZW5A 4NFKF 5DHIA 1HM7A 5IN8A 5I1UA 5ER8A 5B01A 4LLSA 4LPGF 3KB9A 5IMIA 3EFQA 2OPNA 3N1VF 4P0XA 2ZCRA 4LIXA 5A0KA 4JYXA 5ERNA 2AZLA 1HXGA 5CG5A 3KRAA 4JVJF 4LZCA 2E8UA 3NPKA 4LTZA 4RXAA 3W7FA 4NFIF 2ZCOA 4OKMA 5IK0A 4MC8A 5DGNF 4F6XA
chains in the Genus database with same CATH topology
3NF2A 3ZL6A 3N5JF 3P8RA 5B0IA 1YYSA 4F6VA 3EGTA 4E9ZA 1EZFA 2E8VA 3ICKA 2ONGA 2AELA 2Z78A 1N1ZA 3RBMA 3VJBA 3SDQA 4JZXA 2E8WA 3WC9A 4KQUA 1HX9A 5DGMF 3WEHA 2O1OA 3AQ0A 3AQCB 3M00A 2Z52A 4DHDA 4GA3A 3OACA 2ZCQA 1JFAA 5DGSF 5A0JA 4XQSF 1UBWA 1VG6A 3PKOA 4N9UA 5ILYA 1UBVA 5C05A 2QISA 5ILZA 5IM1A 3ASXA 3N49F 4NUAA 3MZVA 1YHKA 4P0WA 5IKHA 3OACB 3ACWA 3VJEA 4LPHF 2Q58A 4DXJA 5JUZF 1VG3A 3SDUA 3SDVA 3BNYA 3LMDA 5E8HA 4RXCA 3V66A 5IMPA 3VJCA 3S9VA 4DWBA 3WEGA 4K10A 5DW7A 3CKEA 5ILIA 4WK5A 3WCMA 4E9UA 4PVYF 2AETA 4EA1A 5E8LA 3KBKA 5B0KA 3RYEA 3ADZA 2J1PA 3N5HF 1KIZA 2PS6A 4P0VA 4UMJA 4DI5A 3SDTA 3VJAA 5ILHA 1RTRA 1WKZA 2ZEUA 3WCLA 3VJDA 2I19A 5IL3A 2Q9YA 2FTZA 1HM4A 4KKMA 1WL1A 5JV2F 3WEFA 4LLTA 4E1EA 3WCAA 3DYGA 2RAHA 1RQIA 1HXCA 3P8LA 3WCGA 1WL0A 2Z4VA 2PS8A 3KRCA 4F62A 5AFXA 3KRAB 1N22A 5DJVF 3P5PA 3ICNA 4JXNA 3DYFA 4DWGA 1YHLA 3G4FA 5JA0F 4ZQ8A 3G4DA 4LZ0A 3LZ9A 3KRCB 5AHUB 3WJOA 2PS4A 4H5EF 2Q9ZA 3APZA 4L2XF 3WEKA 4QXSF 1YYTA 1VG4A 3MAVA 2E4OA 1YYQA 5EROA 3ACXA 2ZY1A 3WCEA 5B0LA 3WCJA 2E95A 3LLWA 3V1VA 4EA0A 4H5CF 3WJNA 1YQ7A 4PVXF 5AYPA 2EWGA 4OGUA 3N45F 1WL2A 5B0MA 3LK5A 4FP4A 3RYWA 1YJ4A 4RXEA 1FPSA 1UBXA 1YYRA 4KK2A 4GAXA 1YHMA 3LJIA 3TC1A 3WCCA 3PH7A 2Z4XA 2F92F 3LEEA 4LOBA 1DI1A 1N24A 4KPDA 5HN7A 5IK9A 3P41A 3WEJA 4KVIA 3TS7A 5HN9A 1V4JA 4NKFA 4KQSA 3Q2QA 3WE9A 2OPMA 1WMWA 2E94A 1KIYA 3ZMBA 3SDRA 5IL8A 3QQVA 3B7LA 2E8XA 1N23A 5E8KA 3LG5A 4DEMF 3ZCDA 3KROA 2E8TA 5B02A 2OA6A 5JV1F 5KSXF 3LSNA 2Z4ZA 3IBAA 4KQ5A 3LGKA 3OYRA 2H8OA 4EA2A 1WL3A 3VJ9A 2F94F 3N3DA 1N1BA 2J5CA 4OKZA 3LVSA 5CG6A 4HD1A 3KRFA 3KROB 4LTVA 3TFPA 5B0JA 1UBYA 4JXYA 5EATA 2J1OA 1YYUA 5IMNA 5HN8A 2E92A 3DYHA 3AE0A 2E93A 4XQRF 3BNXA 4KVDA 3WSBA 4JZBA 4KPJA 3KRFB 3LDWA 4DZWA 3WJKA 4KUXA 4NG6A 5DZ2A 5IKAA 3N46F 5EAUA 5B03A 3M9UA 3CC9A 2Q80A 2Z4WA 4LFGA 5DHKA 5ILDA 1PS1A 3WCFA 4QPFA 5IK6A 2AZJA 1V4IA 4Q23A 2ZCSA 3TFNA 3WCHA 3NRIA 4LFVF 5DJPF 4GP1A 2F8ZF 5IVGA 3VJ8A 5AELA 3OABA 1N21A 3EZ3A 3S4JA 4N1ZF 3LOMA 2OGDA 3V1XA 5ILJA 5B00A 4NFJF 3WEIA 3ZOUA 4LXWA 4KFAA 2E91A 3ACYA 3PYBA 4LZ3A 1V4HA 4MC3A 1HXAA 2ONHA 1VG7A 3OABB 3IPIA 2F7MF 1DGPA 2F8CF 4NKEA 3ZMCA 3Q2ZA 2PS5A 4H5DF 4XQTF 3TFVA 2F9KF 3WCIA 3P5RA 4LFEA 3N0GA 1VG2A 4RYPA 3LGZB 1RQJA 4LA6A 4MC0A 2AZKA 4KWDA 5HNAA 4RNQA 1V4KA 4LA5A 1V4EA 1JFGA 3ICZA 3M01A 3N0FA 2F89F 3ID0A 3NPRA 3PYAA 4RXDA 5ILKA 3UCAA 5EASA 5JV0F 3N1WF 2Z7IA 2Z7HA 5ERMA 2PS7A 3M0GA 4FJQA 5DJRF 3N3LF 3CP6A 3Q1OA 3RMGA 4GP2A 4LUUA 4OMGA 3M02A 4KVWA 5H9DA 3PDEA 2FORA 4KVYA 3ICMA 1N20A 3WCBA 2ZEVA 3KRPA 1WY0A 3QKCA 3SAEA 1YV5A 2P1CA 3WSAA 3AQBB 3WCDA 5A0IA 2DH4A 3N6KF 5DIQF 2VF6A 3Q30A 2Z50A 2E90A 4OMHA 2Z4YA 2AEKA 3KRPB 1ZW5A 4NFKF 5DHIA 1HM7A 5IN8A 5I1UA 5ER8A 5B01A 4LLSA 4LPGF 3KB9A 5IMIA 3EFQA 2OPNA 3N1VF 4P0XA 2ZCRA 4LIXA 5A0KA 4JYXA 5ERNA 2AZLA 1HXGA 5CG5A 3KRAA 4JVJF 4LZCA 2E8UA 3NPKA 4LTZA 4RXAA 3W7FA 4NFIF 2ZCOA 4OKMA 5IK0A 4MC8A 5DGNF 4F6XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3NF2 A;  3ZL6 A;  3N5J F;  3P8R A;  5B0I A;  1YYS A;  4F6V A;  3EGT A;  4E9Z A;  1EZF A;  2E8V A;  3ICK A;  2ONG A;  2AEL A;  2Z78 A;  1N1Z A;  3RBM A;  3VJB A;  3SDQ A;  4JZX A;  2E8W A;  3WC9 A;  4KQU A;  1HX9 A;  5DGM F;  3WEH A;  2O1O A;  3AQ0 A;  3AQC B;  3M00 A;  2Z52 A;  4DHD A;  4GA3 A;  3OAC A;  2ZCQ A;  1JFA A;  5DGS F;  5A0J A;  4XQS F;  1UBW A;  1VG6 A;  3PKO A;  4N9U A;  5ILY A;  1UBV A;  5C05 A;  2QIS A;  5ILZ A;  5IM1 A;  3ASX A;  3N49 F;  4NUA A;  3MZV A;  1YHK A;  4P0W A;  5IKH A;  3OAC B;  3ACW A;  3VJE A;  4LPH F;  2Q58 A;  4DXJ A;  5JUZ F;  1VG3 A;  3SDU A;  3SDV A;  3BNY A;  3LMD A;  5E8H A;  4RXC A;  3V66 A;  5IMP A;  3VJC A;  3S9V A;  4DWB A;  3WEG A;  4K10 A;  5DW7 A;  3CKE A;  5ILI A;  4WK5 A;  3WCM A;  4E9U A;  4PVY F;  2AET A;  4EA1 A;  5E8L A;  3KBK A;  5B0K A;  3RYE A;  3ADZ A;  2J1P A;  3N5H F;  1KIZ A;  2PS6 A;  4P0V A;  4UMJ A;  4DI5 A;  3SDT A;  3VJA A;  5ILH A;  1RTR A;  1WKZ A;  2ZEU A;  3WCL A;  3VJD A;  2I19 A;  5IL3 A;  2Q9Y A;  2FTZ A;  1HM4 A;  4KKM A;  1WL1 A;  5JV2 F;  3WEF A;  4LLT A;  4E1E A;  3WCA A;  3DYG A;  2RAH A;  1RQI A;  1HXC A;  3P8L A;  3WCG A;  1WL0 A;  2Z4V A;  2PS8 A;  3KRC A;  4F62 A;  5AFX A;  3KRA B;  1N22 A;  5DJV F;  3P5P A;  3ICN A;  4JXN A;  3DYF A;  4DWG A;  1YHL A;  3G4F A;  5JA0 F;  4ZQ8 A;  3G4D A;  4LZ0 A;  3LZ9 A;  3KRC B;  5AHU B;  3WJO A;  2PS4 A;  4H5E F;  2Q9Z A;  3APZ A;  4L2X F;  3WEK A;  4QXS F;  1YYT A;  1VG4 A;  3MAV A;  2E4O A;  1YYQ A;  5ERO A;  3ACX A;  2ZY1 A;  3WCE A;  5B0L A;  3WCJ A;  2E95 A;  3LLW A;  3V1V A;  4EA0 A;  4H5C F;  3WJN A;  1YQ7 A;  4PVX F;  5AYP A;  2EWG A;  4OGU A;  3N45 F;  1WL2 A;  5B0M A;  3LK5 A;  4FP4 A;  3RYW A;  1YJ4 A;  4RXE A;  1FPS A;  1UBX A;  1YYR A;  4KK2 A;  4GAX A;  1YHM A;  3LJI A;  3TC1 A;  3WCC A;  3PH7 A;  2Z4X A;  2F92 F;  3LEE A;  4LOB A;  1DI1 A;  1N24 A;  4KPD A;  5HN7 A;  5IK9 A;  3P41 A;  3WEJ A;  4KVI A;  3TS7 A;  5HN9 A;  1V4J A;  4NKF A;  4KQS A;  3Q2Q A;  3WE9 A;  2OPM A;  1WMW A;  2E94 A;  1KIY A;  3ZMB A;  3SDR A;  5IL8 A;  3QQV A;  3B7L A;  2E8X A;  1N23 A;  5E8K A;  3LG5 A;  4DEM F;  3ZCD A;  3KRO A;  2E8T A;  5B02 A;  2OA6 A;  5JV1 F;  5KSX F;  3LSN A;  2Z4Z A;  3IBA A;  4KQ5 A;  3LGK A;  3OYR A;  2H8O A;  4EA2 A;  1WL3 A;  3VJ9 A;  2F94 F;  3N3D A;  1N1B A;  2J5C A;  4OKZ A;  3LVS A;  5CG6 A;  4HD1 A;  3KRF A;  3KRO B;  4LTV A;  3TFP A;  5B0J A;  1UBY A;  4JXY A;  5EAT A;  2J1O A;  1YYU A;  5IMN A;  5HN8 A;  2E92 A;  3DYH A;  3AE0 A;  2E93 A;  4XQR F;  3BNX A;  4KVD A;  3WSB A;  4JZB A;  4KPJ A;  3KRF B;  3LDW A;  4DZW A;  3WJK A;  4KUX A;  4NG6 A;  5DZ2 A;  5IKA A;  3N46 F;  5EAU A;  5B03 A;  3M9U A;  3CC9 A;  2Q80 A;  2Z4W A;  4LFG A;  5DHK A;  5ILD A;  1PS1 A;  3WCF A;  4QPF A;  5IK6 A;  2AZJ A;  1V4I A;  4Q23 A;  2ZCS A;  3TFN A;  3WCH A;  3NRI A;  4LFV F;  5DJP F;  4GP1 A;  2F8Z F;  5IVG A;  3VJ8 A;  5AEL A;  3OAB A;  1N21 A;  3EZ3 A;  3S4J A;  4N1Z F;  3LOM A;  2OGD A;  3V1X A;  5ILJ A;  5B00 A;  4NFJ F;  3WEI A;  3ZOU A;  4LXW A;  4KFA A;  2E91 A;  3ACY A;  3PYB A;  4LZ3 A;  1V4H A;  4MC3 A;  1HXA A;  2ONH A;  1VG7 A;  3OAB B;  3IPI A;  2F7M F;  1DGP A;  2F8C F;  4NKE A;  3ZMC A;  3Q2Z A;  2PS5 A;  4H5D F;  4XQT F;  3TFV A;  2F9K F;  3WCI A;  3P5R A;  4LFE A;  3N0G A;  1VG2 A;  4RYP A;  3LGZ B;  1RQJ A;  4LA6 A;  4MC0 A;  2AZK A;  4KWD A;  5HNA A;  4RNQ A;  1V4K A;  4LA5 A;  1V4E A;  1JFG A;  3ICZ A;  3M01 A;  3N0F A;  2F89 F;  3ID0 A;  3NPR A;  3PYA A;  4RXD A;  5ILK A;  3UCA A;  5EAS A;  5JV0 F;  3N1W F;  2Z7I A;  2Z7H A;  5ERM A;  2PS7 A;  3M0G A;  4FJQ A;  5DJR F;  3N3L F;  3CP6 A;  3Q1O A;  3RMG A;  4GP2 A;  4LUU A;  4OMG A;  3M02 A;  4KVW A;  5H9D A;  3PDE A;  2FOR A;  4KVY A;  3ICM A;  1N20 A;  3WCB A;  2ZEV A;  3KRP A;  1WY0 A;  3QKC A;  3SAE A;  1YV5 A;  2P1C A;  3WSA A;  3AQB B;  3WCD A;  5A0I A;  2DH4 A;  3N6K F;  5DIQ F;  2VF6 A;  3Q30 A;  2Z50 A;  2E90 A;  4OMH A;  2Z4Y A;  2AEK A;  3KRP B;  1ZW5 A;  4NFK F;  5DHI A;  1HM7 A;  5IN8 A;  5I1U A;  5ER8 A;  5B01 A;  4LLS A;  4LPG F;  3KB9 A;  5IMI A;  3EFQ A;  2OPN A;  3N1V F;  4P0X A;  2ZCR A;  4LIX A;  5A0K A;  4JYX A;  5ERN A;  2AZL A;  1HXG A;  5CG5 A;  3KRA A;  4JVJ F;  4LZC A;  2E8U A;  3NPK A;  4LTZ A;  4RXA A;  3W7F A;  4NFI F;  2ZCO A;  4OKM A;  5IK0 A;  4MC8 A;  5DGN F;  4F6X A; 
#chains in the Genus database with same CATH topology
 3NF2 A;  3ZL6 A;  3N5J F;  3P8R A;  5B0I A;  1YYS A;  4F6V A;  3EGT A;  4E9Z A;  1EZF A;  2E8V A;  3ICK A;  2ONG A;  2AEL A;  2Z78 A;  1N1Z A;  3RBM A;  3VJB A;  3SDQ A;  4JZX A;  2E8W A;  3WC9 A;  4KQU A;  1HX9 A;  5DGM F;  3WEH A;  2O1O A;  3AQ0 A;  3AQC B;  3M00 A;  2Z52 A;  4DHD A;  4GA3 A;  3OAC A;  2ZCQ A;  1JFA A;  5DGS F;  5A0J A;  4XQS F;  1UBW A;  1VG6 A;  3PKO A;  4N9U A;  5ILY A;  1UBV A;  5C05 A;  2QIS A;  5ILZ A;  5IM1 A;  3ASX A;  3N49 F;  4NUA A;  3MZV A;  1YHK A;  4P0W A;  5IKH A;  3OAC B;  3ACW A;  3VJE A;  4LPH F;  2Q58 A;  4DXJ A;  5JUZ F;  1VG3 A;  3SDU A;  3SDV A;  3BNY A;  3LMD A;  5E8H A;  4RXC A;  3V66 A;  5IMP A;  3VJC A;  3S9V A;  4DWB A;  3WEG A;  4K10 A;  5DW7 A;  3CKE A;  5ILI A;  4WK5 A;  3WCM A;  4E9U A;  4PVY F;  2AET A;  4EA1 A;  5E8L A;  3KBK A;  5B0K A;  3RYE A;  3ADZ A;  2J1P A;  3N5H F;  1KIZ A;  2PS6 A;  4P0V A;  4UMJ A;  4DI5 A;  3SDT A;  3VJA A;  5ILH A;  1RTR A;  1WKZ A;  2ZEU A;  3WCL A;  3VJD A;  2I19 A;  5IL3 A;  2Q9Y A;  2FTZ A;  1HM4 A;  4KKM A;  1WL1 A;  5JV2 F;  3WEF A;  4LLT A;  4E1E A;  3WCA A;  3DYG A;  2RAH A;  1RQI A;  1HXC A;  3P8L A;  3WCG A;  1WL0 A;  2Z4V A;  2PS8 A;  3KRC A;  4F62 A;  5AFX A;  3KRA B;  1N22 A;  5DJV F;  3P5P A;  3ICN A;  4JXN A;  3DYF A;  4DWG A;  1YHL A;  3G4F A;  5JA0 F;  4ZQ8 A;  3G4D A;  4LZ0 A;  3LZ9 A;  3KRC B;  5AHU B;  3WJO A;  2PS4 A;  4H5E F;  2Q9Z A;  3APZ A;  4L2X F;  3WEK A;  4QXS F;  1YYT A;  1VG4 A;  3MAV A;  2E4O A;  1YYQ A;  5ERO A;  3ACX A;  2ZY1 A;  3WCE A;  5B0L A;  3WCJ A;  2E95 A;  3LLW A;  3V1V A;  4EA0 A;  4H5C F;  3WJN A;  1YQ7 A;  4PVX F;  5AYP A;  2EWG A;  4OGU A;  3N45 F;  1WL2 A;  5B0M A;  3LK5 A;  4FP4 A;  3RYW A;  1YJ4 A;  4RXE A;  1FPS A;  1UBX A;  1YYR A;  4KK2 A;  4GAX A;  1YHM A;  3LJI A;  3TC1 A;  3WCC A;  3PH7 A;  2Z4X A;  2F92 F;  3LEE A;  4LOB A;  1DI1 A;  1N24 A;  4KPD A;  5HN7 A;  5IK9 A;  3P41 A;  3WEJ A;  4KVI A;  3TS7 A;  5HN9 A;  1V4J A;  4NKF A;  4KQS A;  3Q2Q A;  3WE9 A;  2OPM A;  1WMW A;  2E94 A;  1KIY A;  3ZMB A;  3SDR A;  5IL8 A;  3QQV A;  3B7L A;  2E8X A;  1N23 A;  5E8K A;  3LG5 A;  4DEM F;  3ZCD A;  3KRO A;  2E8T A;  5B02 A;  2OA6 A;  5JV1 F;  5KSX F;  3LSN A;  2Z4Z A;  3IBA A;  4KQ5 A;  3LGK A;  3OYR A;  2H8O A;  4EA2 A;  1WL3 A;  3VJ9 A;  2F94 F;  3N3D A;  1N1B A;  2J5C A;  4OKZ A;  3LVS A;  5CG6 A;  4HD1 A;  3KRF A;  3KRO B;  4LTV A;  3TFP A;  5B0J A;  1UBY A;  4JXY A;  5EAT A;  2J1O A;  1YYU A;  5IMN A;  5HN8 A;  2E92 A;  3DYH A;  3AE0 A;  2E93 A;  4XQR F;  3BNX A;  4KVD A;  3WSB A;  4JZB A;  4KPJ A;  3KRF B;  3LDW A;  4DZW A;  3WJK A;  4KUX A;  4NG6 A;  5DZ2 A;  5IKA A;  3N46 F;  5EAU A;  5B03 A;  3M9U A;  3CC9 A;  2Q80 A;  2Z4W A;  4LFG A;  5DHK A;  5ILD A;  1PS1 A;  3WCF A;  4QPF A;  5IK6 A;  2AZJ A;  1V4I A;  4Q23 A;  2ZCS A;  3TFN A;  3WCH A;  3NRI A;  4LFV F;  5DJP F;  4GP1 A;  2F8Z F;  5IVG A;  3VJ8 A;  5AEL A;  3OAB A;  1N21 A;  3EZ3 A;  3S4J A;  4N1Z F;  3LOM A;  2OGD A;  3V1X A;  5ILJ A;  5B00 A;  4NFJ F;  3WEI A;  3ZOU A;  4LXW A;  4KFA A;  2E91 A;  3ACY A;  3PYB A;  4LZ3 A;  1V4H A;  4MC3 A;  1HXA A;  2ONH A;  1VG7 A;  3OAB B;  3IPI A;  2F7M F;  1DGP A;  2F8C F;  4NKE A;  3ZMC A;  3Q2Z A;  2PS5 A;  4H5D F;  4XQT F;  3TFV A;  2F9K F;  3WCI A;  3P5R A;  4LFE A;  3N0G A;  1VG2 A;  4RYP A;  3LGZ B;  1RQJ A;  4LA6 A;  4MC0 A;  2AZK A;  4KWD A;  5HNA A;  4RNQ A;  1V4K A;  4LA5 A;  1V4E A;  1JFG A;  3ICZ A;  3M01 A;  3N0F A;  2F89 F;  3ID0 A;  3NPR A;  3PYA A;  4RXD A;  5ILK A;  3UCA A;  5EAS A;  5JV0 F;  3N1W F;  2Z7I A;  2Z7H A;  5ERM A;  2PS7 A;  3M0G A;  4FJQ A;  5DJR F;  3N3L F;  3CP6 A;  3Q1O A;  3RMG A;  4GP2 A;  4LUU A;  4OMG A;  3M02 A;  4KVW A;  5H9D A;  3PDE A;  2FOR A;  4KVY A;  3ICM A;  1N20 A;  3WCB A;  2ZEV A;  3KRP A;  1WY0 A;  3QKC A;  3SAE A;  1YV5 A;  2P1C A;  3WSA A;  3AQB B;  3WCD A;  5A0I A;  2DH4 A;  3N6K F;  5DIQ F;  2VF6 A;  3Q30 A;  2Z50 A;  2E90 A;  4OMH A;  2Z4Y A;  2AEK A;  3KRP B;  1ZW5 A;  4NFK F;  5DHI A;  1HM7 A;  5IN8 A;  5I1U A;  5ER8 A;  5B01 A;  4LLS A;  4LPG F;  3KB9 A;  5IMI A;  3EFQ A;  2OPN A;  3N1V F;  4P0X A;  2ZCR A;  4LIX A;  5A0K A;  4JYX A;  5ERN A;  2AZL A;  1HXG A;  5CG5 A;  3KRA A;  4JVJ F;  4LZC A;  2E8U A;  3NPK A;  4LTZ A;  4RXA A;  3W7F A;  4NFI F;  2ZCO A;  4OKM A;  5IK0 A;  4MC8 A;  5DGN F;  4F6X A; 
#chains in the Genus database with same CATH homology
 3NF2 A;  3ZL6 A;  3N5J F;  3P8R A;  5B0I A;  1YYS A;  4F6V A;  3EGT A;  4E9Z A;  1EZF A;  2E8V A;  3ICK A;  2ONG A;  2AEL A;  2Z78 A;  1N1Z A;  3RBM A;  3VJB A;  3SDQ A;  4JZX A;  2E8W A;  3WC9 A;  4KQU A;  1HX9 A;  5DGM F;  3WEH A;  2O1O A;  3AQ0 A;  3AQC B;  3M00 A;  2Z52 A;  4DHD A;  4GA3 A;  3OAC A;  2ZCQ A;  1JFA A;  5DGS F;  5A0J A;  4XQS F;  1UBW A;  1VG6 A;  3PKO A;  4N9U A;  5ILY A;  1UBV A;  5C05 A;  2QIS A;  5ILZ A;  5IM1 A;  3ASX A;  3N49 F;  4NUA A;  3MZV A;  1YHK A;  4P0W A;  5IKH A;  3OAC B;  3ACW A;  3VJE A;  4LPH F;  2Q58 A;  4DXJ A;  5JUZ F;  1VG3 A;  3SDU A;  3SDV A;  3BNY A;  3LMD A;  5E8H A;  4RXC A;  3V66 A;  5IMP A;  3VJC A;  3S9V A;  4DWB A;  3WEG A;  4K10 A;  5DW7 A;  3CKE A;  5ILI A;  4WK5 A;  3WCM A;  4E9U A;  4PVY F;  2AET A;  4EA1 A;  5E8L A;  3KBK A;  5B0K A;  3RYE A;  3ADZ A;  2J1P A;  3N5H F;  1KIZ A;  2PS6 A;  4P0V A;  4UMJ A;  4DI5 A;  3SDT A;  3VJA A;  5ILH A;  1RTR A;  1WKZ A;  2ZEU A;  3WCL A;  3VJD A;  2I19 A;  5IL3 A;  2Q9Y A;  2FTZ A;  1HM4 A;  4KKM A;  1WL1 A;  5JV2 F;  3WEF A;  4LLT A;  4E1E A;  3WCA A;  3DYG A;  2RAH A;  1RQI A;  1HXC A;  3P8L A;  3WCG A;  1WL0 A;  2Z4V A;  2PS8 A;  3KRC A;  4F62 A;  5AFX A;  3KRA B;  1N22 A;  5DJV F;  3P5P A;  3ICN A;  4JXN A;  3DYF A;  4DWG A;  1YHL A;  3G4F A;  5JA0 F;  4ZQ8 A;  3G4D A;  4LZ0 A;  3LZ9 A;  3KRC B;  5AHU B;  3WJO A;  2PS4 A;  4H5E F;  2Q9Z A;  3APZ A;  4L2X F;  3WEK A;  4QXS F;  1YYT A;  1VG4 A;  3MAV A;  2E4O A;  1YYQ A;  5ERO A;  3ACX A;  2ZY1 A;  3WCE A;  5B0L A;  3WCJ A;  2E95 A;  3LLW A;  3V1V A;  4EA0 A;  4H5C F;  3WJN A;  1YQ7 A;  4PVX F;  5AYP A;  2EWG A;  4OGU A;  3N45 F;  1WL2 A;  5B0M A;  3LK5 A;  4FP4 A;  3RYW A;  1YJ4 A;  4RXE A;  1FPS A;  1UBX A;  1YYR A;  4KK2 A;  4GAX A;  1YHM A;  3LJI A;  3TC1 A;  3WCC A;  3PH7 A;  2Z4X A;  2F92 F;  3LEE A;  4LOB A;  1DI1 A;  1N24 A;  4KPD A;  5HN7 A;  5IK9 A;  3P41 A;  3WEJ A;  4KVI A;  3TS7 A;  5HN9 A;  1V4J A;  4NKF A;  4KQS A;  3Q2Q A;  3WE9 A;  2OPM A;  1WMW A;  2E94 A;  1KIY A;  3ZMB A;  3SDR A;  5IL8 A;  3QQV A;  3B7L A;  2E8X A;  1N23 A;  5E8K A;  3LG5 A;  4DEM F;  3ZCD A;  3KRO A;  2E8T A;  5B02 A;  2OA6 A;  5JV1 F;  5KSX F;  3LSN A;  2Z4Z A;  3IBA A;  4KQ5 A;  3LGK A;  3OYR A;  2H8O A;  4EA2 A;  1WL3 A;  3VJ9 A;  2F94 F;  3N3D A;  1N1B A;  2J5C A;  4OKZ A;  3LVS A;  5CG6 A;  4HD1 A;  3KRF A;  3KRO B;  4LTV A;  3TFP A;  5B0J A;  1UBY A;  4JXY A;  5EAT A;  2J1O A;  1YYU A;  5IMN A;  5HN8 A;  2E92 A;  3DYH A;  3AE0 A;  2E93 A;  4XQR F;  3BNX A;  4KVD A;  3WSB A;  4JZB A;  4KPJ A;  3KRF B;  3LDW A;  4DZW A;  3WJK A;  4KUX A;  4NG6 A;  5DZ2 A;  5IKA A;  3N46 F;  5EAU A;  5B03 A;  3M9U A;  3CC9 A;  2Q80 A;  2Z4W A;  4LFG A;  5DHK A;  5ILD A;  1PS1 A;  3WCF A;  4QPF A;  5IK6 A;  2AZJ A;  1V4I A;  4Q23 A;  2ZCS A;  3TFN A;  3WCH A;  3NRI A;  4LFV F;  5DJP F;  4GP1 A;  2F8Z F;  5IVG A;  3VJ8 A;  5AEL A;  3OAB A;  1N21 A;  3EZ3 A;  3S4J A;  4N1Z F;  3LOM A;  2OGD A;  3V1X A;  5ILJ A;  5B00 A;  4NFJ F;  3WEI A;  3ZOU A;  4LXW A;  4KFA A;  2E91 A;  3ACY A;  3PYB A;  4LZ3 A;  1V4H A;  4MC3 A;  1HXA A;  2ONH A;  1VG7 A;  3OAB B;  3IPI A;  2F7M F;  1DGP A;  2F8C F;  4NKE A;  3ZMC A;  3Q2Z A;  2PS5 A;  4H5D F;  4XQT F;  3TFV A;  2F9K F;  3WCI A;  3P5R A;  4LFE A;  3N0G A;  1VG2 A;  4RYP A;  3LGZ B;  1RQJ A;  4LA6 A;  4MC0 A;  2AZK A;  4KWD A;  5HNA A;  4RNQ A;  1V4K A;  4LA5 A;  1V4E A;  1JFG A;  3ICZ A;  3M01 A;  3N0F A;  2F89 F;  3ID0 A;  3NPR A;  3PYA A;  4RXD A;  5ILK A;  3UCA A;  5EAS A;  5JV0 F;  3N1W F;  2Z7I A;  2Z7H A;  5ERM A;  2PS7 A;  3M0G A;  4FJQ A;  5DJR F;  3N3L F;  3CP6 A;  3Q1O A;  3RMG A;  4GP2 A;  4LUU A;  4OMG A;  3M02 A;  4KVW A;  5H9D A;  3PDE A;  2FOR A;  4KVY A;  3ICM A;  1N20 A;  3WCB A;  2ZEV A;  3KRP A;  1WY0 A;  3QKC A;  3SAE A;  1YV5 A;  2P1C A;  3WSA A;  3AQB B;  3WCD A;  5A0I A;  2DH4 A;  3N6K F;  5DIQ F;  2VF6 A;  3Q30 A;  2Z50 A;  2E90 A;  4OMH A;  2Z4Y A;  2AEK A;  3KRP B;  1ZW5 A;  4NFK F;  5DHI A;  1HM7 A;  5IN8 A;  5I1U A;  5ER8 A;  5B01 A;  4LLS A;  4LPG F;  3KB9 A;  5IMI A;  3EFQ A;  2OPN A;  3N1V F;  4P0X A;  2ZCR A;  4LIX A;  5A0K A;  4JYX A;  5ERN A;  2AZL A;  1HXG A;  5CG5 A;  3KRA A;  4JVJ F;  4LZC A;  2E8U A;  3NPK A;  4LTZ A;  4RXA A;  3W7F A;  4NFI F;  2ZCO A;  4OKM A;  5IK0 A;  4MC8 A;  5DGN F;  4F6X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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