3TFVA

Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1154
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
284
structure length
284
Chain Sequence
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEYHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVEKRKKAKLFHEINSKY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Staphylococcus aureus
molecule keywords Dehydrosqualene synthase
total genus 115
structure length 284
sequence length 284
ec nomenclature ec 2.5.1.96: 4,4'-diapophytoene synthase.
pdb deposition date 2011-08-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3tfvA00
2EWGA 1YYTA 3AQCB 2Z52A 3IPIA 1WKZA 4LTVA 4LZCA 1WMWA 3VJDA 3VJEA 2Z7IA 5DW7A 3SDQA 3IBAA 3M00A 1YYSA 2OPMA 4NFKF 5DJPF 3VJ8A 3ID0A 2Z4WA 4OGUA 4LLSA 5EASA 4KVDA 3S4JA 3WCEA 1V4KA 1VG3A 3MZVA 1HXGA 2E8WA 3ZOUA 1YYUA 3N0FA 5HN7A 2AELA 3PKOA 2H8OA 2F8CF 3KROB 2OGDA 4FJQA 5H9DA 4RYPA 5B0KA 2ONGA 5IL3A 5A0IA 5E8HA 2PS7A 1N24A 1RQJA 5IM1A 4FP4A 1DI1A 3LMDA 3P8RA 3LLWA 5IKHA 3DYGA 3QKCA 1UBVA 1V4HA 2F9KF 3OABB 3WCGA 3ACXA 5B00A 5IK6A 3ICZA 3TC1A 4KK2A 1N21A 3LK5A 3EGTA 2FTZA 5ILKA 4EA2A 3VJCA 2Z78A 2AEKA 3RYWA 1UBXA 3WC9A 1KIYA 2E8VA 5B0JA 5HN8A 3WEFA 3WE9A 1HM4A 5JA0F 4JXNA 4LPGF 1ZW5A 5IL8A 3AQ0A 2E8XA 1RTRA 2E90A 2AZLA 3N1WF 3V66A 1N1BA 3KRAB 4LA5A 4LPHF 4GA3A 3KRCA 4KPDA 3BNXA 3PYBA 1YJ4A 2QISA 4JXYA 4P0VA 4LIXA 4H5CF 4RXDA 2FORA 2Z7HA 3VJ9A 3ZCDA 4F6VA 3WEHA 3B7LA 1VG7A 3ICKA 1HXAA 4H5EF 3M01A 5ILZA 1YV5A 3NPKA 3KRPA 4KQSA 4XQRF 3Q1OA 3BNYA 4F62A 5B0LA 5ILDA 3N49F 3KB9A 3AE0A 4QPFA 3N0GA 1WL1A 4EA1A 1WL2A 5DIQF 4F6XA 5A0JA 5DZ2A 4P0XA 5IMIA 3G4DA 2Z4VA 4RNQA 3OACB 3KRCB 5E8LA 3SDTA 4OMHA 3WCCA 3WCJA 3WCMA 3WCDA 2ZEVA 3ADZA 3RYEA 4E9UA 3V1XA 5B0IA 3LGZB 4MC8A 3LGKA 3EFQA 5E8KA 4MC3A 4OKZA 1JFAA 2OPNA 4UMJA 2Z4XA 3N6KF 3ICMA 1HXCA 2ZCOA 3KRFA 3ZL6A 3N45F 2RAHA 5AHUB 3WEGA 2AETA 4KQ5A 5IN8A 3M9UA 4RXAA 3TFPA 3PDEA 4LTZA 3LG5A 5IKAA 3M0GA 2O1OA 5AFXA 1HM7A 3N46F 3TFVA 3DYHA 2Z50A 2E93A 2AZKA 1YQ7A 3SDVA 5EAUA 4L2XF 4GAXA 2F94F 3CP6A 4GP2A 4NUAA 3W7FA 1VG2A 5AYPA 1WL3A 4K10A 3NPRA 2F8ZF 4NG6A 5JV2F 5ILIA 4KQUA 4JYXA 2J1PA 4PVYF 2PS4A 3ICNA 2J1OA 2P1CA 4DHDA 3N3DA 4WK5A 5A0KA 2ZY1A 1WY0A 5IMPA 5ILJA 4LUUA 5DGMF 2ZEUA 3VJBA 4JZXA 3WCLA 3ACYA 4H5DF 4LZ0A 3ZMBA 2ZCSA 3SAEA 4E9ZA 4KPJA 4NKEA 2PS5A 4RXEA 5ER8A 1UBWA 3WJOA 5IK0A 3APZA 3P41A 1YHLA 4DI5A 5DHIA 4MC0A 3KBKA 3RBMA 4KVWA 4NKFA 4LFGA 4KKMA 3RMGA 1JFGA 2Q58A 2ONHA 2VF6A 3WEJA 4XQSF 2F92F 2OA6A 4DEMF 4EA0A 3Q30A 4JZBA 3WEIA 3M02A 4P0WA 4LFVF 1V4JA 2E4OA 3N5JF 2E94A 5HN9A 3KROA 4KVIA 3PYAA 1HX9A 4LFEA 4XQTF 4QXSF 3OYRA 1EZFA 3SDRA 5HNAA 3WJNA 1YYQA 5ILYA 4KVYA 4LOBA 5DGNF 4DWGA 5DJRF 4DXJA 1V4IA 3KRPB 4KUXA 2ZCQA 4N1ZF 2E8TA 3NF2A 3OABA 3N3LF 3UCAA 3VJAA 1UBYA 3WJKA 3LZ9A 2E91A 5IMNA 2PS6A 1N20A 5JV0F 3ASXA 5C05A 1V4EA 3TFNA 4KWDA 3WEKA 3LSNA 4OMGA 2PS8A 5JUZF 4E1EA 3LOMA 3P5RA 4JVJF 5IVGA 3LVSA 3N1VF 5EROA 3P8LA 3WCAA 3LEEA 4ZQ8A 3KRAA 3WCFA 2E92A 2I19A 3KRFB 5DHKA 2Z4YA 2ZCRA 4NFIF 3ACWA 5B01A 5DJVF 2Q9YA 3WSAA 3LDWA 3QQVA 1N1ZA 5IK9A 2Q80A 1VG6A 3MAVA 3N5HF 3LJIA 5AELA 5CG6A 1RQIA 3V1VA 4PVXF 5B03A 3PH7A 2E95A 4DWBA 3EZ3A 3SDUA 4Q23A 5CG5A 1FPSA 5ERMA 3DYFA 2F89F 3ZMCA 2J5CA 5EATA 4LZ3A 5DGSF 5B0MA 3WSBA 4NFJF 4OKMA 3OACA 2F7MF 4N9UA 4LA6A 5JV1F 2Z4ZA 3WCIA 2AZJA 3AQBB 4LXWA 4RXCA 2Q9ZA 3CC9A 5B02A 3P5PA 2E8UA 3S9VA 1YHMA 4HD1A 3Q2ZA 3CKEA 5ILHA 2DH4A 1PS1A 3Q2QA 4DZWA 5ERNA 1DGPA 1YHKA 3WCHA 4GP1A 4KFAA 3TS7A 5KSXF 1WL0A 3G4FA 1VG4A 3NRIA 1N22A 1N23A 1YYRA 3WCBA 4LLTA 5I1UA 1KIZA
chains in the Genus database with same CATH superfamily
2EWGA 1YYTA 3AQCB 2Z52A 3IPIA 1WKZA 4LTVA 4LZCA 1WMWA 3VJDA 3VJEA 2Z7IA 5DW7A 3SDQA 3IBAA 3M00A 1YYSA 2OPMA 4NFKF 5DJPF 3VJ8A 3ID0A 2Z4WA 4OGUA 4LLSA 5EASA 4KVDA 3S4JA 3WCEA 1V4KA 1VG3A 3MZVA 1HXGA 2E8WA 3ZOUA 1YYUA 3N0FA 5HN7A 2AELA 3PKOA 2H8OA 2F8CF 3KROB 2OGDA 4FJQA 5H9DA 4RYPA 5B0KA 2ONGA 5IL3A 5A0IA 5E8HA 2PS7A 1N24A 1RQJA 5IM1A 4FP4A 1DI1A 3LMDA 3P8RA 3LLWA 5IKHA 3DYGA 3QKCA 1UBVA 1V4HA 2F9KF 3OABB 3WCGA 3ACXA 5B00A 5IK6A 3ICZA 3TC1A 4KK2A 1N21A 3LK5A 3EGTA 2FTZA 5ILKA 4EA2A 3VJCA 2Z78A 2AEKA 3RYWA 1UBXA 3WC9A 1KIYA 2E8VA 5B0JA 5HN8A 3WEFA 3WE9A 1HM4A 5JA0F 4JXNA 4LPGF 1ZW5A 5IL8A 3AQ0A 2E8XA 1RTRA 2E90A 2AZLA 3N1WF 3V66A 1N1BA 3KRAB 4LA5A 4LPHF 4GA3A 3KRCA 4KPDA 3BNXA 3PYBA 1YJ4A 2QISA 4JXYA 4P0VA 4LIXA 4H5CF 4RXDA 2FORA 2Z7HA 3VJ9A 3ZCDA 4F6VA 3WEHA 3B7LA 1VG7A 3ICKA 1HXAA 4H5EF 3M01A 5ILZA 1YV5A 3NPKA 3KRPA 4KQSA 4XQRF 3Q1OA 3BNYA 4F62A 5B0LA 5ILDA 3N49F 3KB9A 3AE0A 4QPFA 3N0GA 1WL1A 4EA1A 1WL2A 5DIQF 4F6XA 5A0JA 5DZ2A 4P0XA 5IMIA 3G4DA 2Z4VA 4RNQA 3OACB 3KRCB 5E8LA 3SDTA 4OMHA 3WCCA 3WCJA 3WCMA 3WCDA 2ZEVA 3ADZA 3RYEA 4E9UA 3V1XA 5B0IA 3LGZB 4MC8A 3LGKA 3EFQA 5E8KA 4MC3A 4OKZA 1JFAA 2OPNA 4UMJA 2Z4XA 3N6KF 3ICMA 1HXCA 2ZCOA 3KRFA 3ZL6A 3N45F 2RAHA 5AHUB 3WEGA 2AETA 4KQ5A 5IN8A 3M9UA 4RXAA 3TFPA 3PDEA 4LTZA 3LG5A 5IKAA 3M0GA 2O1OA 5AFXA 1HM7A 3N46F 3TFVA 3DYHA 2Z50A 2E93A 2AZKA 1YQ7A 3SDVA 5EAUA 4L2XF 4GAXA 2F94F 3CP6A 4GP2A 4NUAA 3W7FA 1VG2A 5AYPA 1WL3A 4K10A 3NPRA 2F8ZF 4NG6A 5JV2F 5ILIA 4KQUA 4JYXA 2J1PA 4PVYF 2PS4A 3ICNA 2J1OA 2P1CA 4DHDA 3N3DA 4WK5A 5A0KA 2ZY1A 1WY0A 5IMPA 5ILJA 4LUUA 5DGMF 2ZEUA 3VJBA 4JZXA 3WCLA 3ACYA 4H5DF 4LZ0A 3ZMBA 2ZCSA 3SAEA 4E9ZA 4KPJA 4NKEA 2PS5A 4RXEA 5ER8A 1UBWA 3WJOA 5IK0A 3APZA 3P41A 1YHLA 4DI5A 5DHIA 4MC0A 3KBKA 3RBMA 4KVWA 4NKFA 4LFGA 4KKMA 3RMGA 1JFGA 2Q58A 2ONHA 2VF6A 3WEJA 4XQSF 2F92F 2OA6A 4DEMF 4EA0A 3Q30A 4JZBA 3WEIA 3M02A 4P0WA 4LFVF 1V4JA 2E4OA 3N5JF 2E94A 5HN9A 3KROA 4KVIA 3PYAA 1HX9A 4LFEA 4XQTF 4QXSF 3OYRA 1EZFA 3SDRA 5HNAA 3WJNA 1YYQA 5ILYA 4KVYA 4LOBA 5DGNF 4DWGA 5DJRF 4DXJA 1V4IA 3KRPB 4KUXA 2ZCQA 4N1ZF 2E8TA 3NF2A 3OABA 3N3LF 3UCAA 3VJAA 1UBYA 3WJKA 3LZ9A 2E91A 5IMNA 2PS6A 1N20A 5JV0F 3ASXA 5C05A 1V4EA 3TFNA 4KWDA 3WEKA 3LSNA 4OMGA 2PS8A 5JUZF 4E1EA 3LOMA 3P5RA 4JVJF 5IVGA 3LVSA 3N1VF 5EROA 3P8LA 3WCAA 3LEEA 4ZQ8A 3KRAA 3WCFA 2E92A 2I19A 3KRFB 5DHKA 2Z4YA 2ZCRA 4NFIF 3ACWA 5B01A 5DJVF 2Q9YA 3WSAA 3LDWA 3QQVA 1N1ZA 5IK9A 2Q80A 1VG6A 3MAVA 3N5HF 3LJIA 5AELA 5CG6A 1RQIA 3V1VA 4PVXF 5B03A 3PH7A 2E95A 4DWBA 3EZ3A 3SDUA 4Q23A 5CG5A 1FPSA 5ERMA 3DYFA 2F89F 3ZMCA 2J5CA 5EATA 4LZ3A 5DGSF 5B0MA 3WSBA 4NFJF 4OKMA 3OACA 2F7MF 4N9UA 4LA6A 5JV1F 2Z4ZA 3WCIA 2AZJA 3AQBB 4LXWA 4RXCA 2Q9ZA 3CC9A 5B02A 3P5PA 2E8UA 3S9VA 1YHMA 4HD1A 3Q2ZA 3CKEA 5ILHA 2DH4A 1PS1A 3Q2QA 4DZWA 5ERNA 1DGPA 1YHKA 3WCHA 4GP1A 4KFAA 3TS7A 5KSXF 1WL0A 3G4FA 1VG4A 3NRIA 1N22A 1N23A 1YYRA 3WCBA 4LLTA 5I1UA 1KIZA
chains in the Genus database with same CATH topology
2EWGA 1YYTA 3AQCB 2Z52A 3IPIA 1WKZA 4LTVA 4LZCA 1WMWA 3VJDA 3VJEA 2Z7IA 5DW7A 3SDQA 3IBAA 3M00A 1YYSA 2OPMA 4NFKF 5DJPF 3VJ8A 3ID0A 2Z4WA 4OGUA 4LLSA 5EASA 4KVDA 3S4JA 3WCEA 1V4KA 1VG3A 3MZVA 1HXGA 2E8WA 3ZOUA 1YYUA 3N0FA 5HN7A 2AELA 3PKOA 2H8OA 2F8CF 3KROB 2OGDA 4FJQA 5H9DA 4RYPA 5B0KA 2ONGA 5IL3A 5A0IA 5E8HA 2PS7A 1N24A 1RQJA 5IM1A 4FP4A 1DI1A 3LMDA 3P8RA 3LLWA 5IKHA 3DYGA 3QKCA 1UBVA 1V4HA 2F9KF 3OABB 3WCGA 3ACXA 5B00A 5IK6A 3ICZA 3TC1A 4KK2A 1N21A 3LK5A 3EGTA 2FTZA 5ILKA 4EA2A 3VJCA 2Z78A 2AEKA 3RYWA 1UBXA 3WC9A 1KIYA 2E8VA 5B0JA 5HN8A 3WEFA 3WE9A 1HM4A 5JA0F 4JXNA 4LPGF 1ZW5A 5IL8A 3AQ0A 2E8XA 1RTRA 2E90A 2AZLA 3N1WF 3V66A 1N1BA 3KRAB 4LA5A 4LPHF 4GA3A 3KRCA 4KPDA 3BNXA 3PYBA 1YJ4A 2QISA 4JXYA 4P0VA 4LIXA 4H5CF 4RXDA 2FORA 2Z7HA 3VJ9A 3ZCDA 4F6VA 3WEHA 3B7LA 1VG7A 3ICKA 1HXAA 4H5EF 3M01A 5ILZA 1YV5A 3NPKA 3KRPA 4KQSA 4XQRF 3Q1OA 3BNYA 4F62A 5B0LA 5ILDA 3N49F 3KB9A 3AE0A 4QPFA 3N0GA 1WL1A 4EA1A 1WL2A 5DIQF 4F6XA 5A0JA 5DZ2A 4P0XA 5IMIA 3G4DA 2Z4VA 4RNQA 3OACB 3KRCB 5E8LA 3SDTA 4OMHA 3WCCA 3WCJA 3WCMA 3WCDA 2ZEVA 3ADZA 3RYEA 4E9UA 3V1XA 5B0IA 3LGZB 4MC8A 3LGKA 3EFQA 5E8KA 4MC3A 4OKZA 1JFAA 2OPNA 4UMJA 2Z4XA 3N6KF 3ICMA 1HXCA 2ZCOA 3KRFA 3ZL6A 3N45F 2RAHA 5AHUB 3WEGA 2AETA 4KQ5A 5IN8A 3M9UA 4RXAA 3TFPA 3PDEA 4LTZA 3LG5A 5IKAA 3M0GA 2O1OA 5AFXA 1HM7A 3N46F 3TFVA 3DYHA 2Z50A 2E93A 2AZKA 1YQ7A 3SDVA 5EAUA 4L2XF 4GAXA 2F94F 3CP6A 4GP2A 4NUAA 3W7FA 1VG2A 5AYPA 1WL3A 4K10A 3NPRA 2F8ZF 4NG6A 5JV2F 5ILIA 4KQUA 4JYXA 2J1PA 4PVYF 2PS4A 3ICNA 2J1OA 2P1CA 4DHDA 3N3DA 4WK5A 5A0KA 2ZY1A 1WY0A 5IMPA 5ILJA 4LUUA 5DGMF 2ZEUA 3VJBA 4JZXA 3WCLA 3ACYA 4H5DF 4LZ0A 3ZMBA 2ZCSA 3SAEA 4E9ZA 4KPJA 4NKEA 2PS5A 4RXEA 5ER8A 1UBWA 3WJOA 5IK0A 3APZA 3P41A 1YHLA 4DI5A 5DHIA 4MC0A 3KBKA 3RBMA 4KVWA 4NKFA 4LFGA 4KKMA 3RMGA 1JFGA 2Q58A 2ONHA 2VF6A 3WEJA 4XQSF 2F92F 2OA6A 4DEMF 4EA0A 3Q30A 4JZBA 3WEIA 3M02A 4P0WA 4LFVF 1V4JA 2E4OA 3N5JF 2E94A 5HN9A 3KROA 4KVIA 3PYAA 1HX9A 4LFEA 4XQTF 4QXSF 3OYRA 1EZFA 3SDRA 5HNAA 3WJNA 1YYQA 5ILYA 4KVYA 4LOBA 5DGNF 4DWGA 5DJRF 4DXJA 1V4IA 3KRPB 4KUXA 2ZCQA 4N1ZF 2E8TA 3NF2A 3OABA 3N3LF 3UCAA 3VJAA 1UBYA 3WJKA 3LZ9A 2E91A 5IMNA 2PS6A 1N20A 5JV0F 3ASXA 5C05A 1V4EA 3TFNA 4KWDA 3WEKA 3LSNA 4OMGA 2PS8A 5JUZF 4E1EA 3LOMA 3P5RA 4JVJF 5IVGA 3LVSA 3N1VF 5EROA 3P8LA 3WCAA 3LEEA 4ZQ8A 3KRAA 3WCFA 2E92A 2I19A 3KRFB 5DHKA 2Z4YA 2ZCRA 4NFIF 3ACWA 5B01A 5DJVF 2Q9YA 3WSAA 3LDWA 3QQVA 1N1ZA 5IK9A 2Q80A 1VG6A 3MAVA 3N5HF 3LJIA 5AELA 5CG6A 1RQIA 3V1VA 4PVXF 5B03A 3PH7A 2E95A 4DWBA 3EZ3A 3SDUA 4Q23A 5CG5A 1FPSA 5ERMA 3DYFA 2F89F 3ZMCA 2J5CA 5EATA 4LZ3A 5DGSF 5B0MA 3WSBA 4NFJF 4OKMA 3OACA 2F7MF 4N9UA 4LA6A 5JV1F 2Z4ZA 3WCIA 2AZJA 3AQBB 4LXWA 4RXCA 2Q9ZA 3CC9A 5B02A 3P5PA 2E8UA 3S9VA 1YHMA 4HD1A 3Q2ZA 3CKEA 5ILHA 2DH4A 1PS1A 3Q2QA 4DZWA 5ERNA 1DGPA 1YHKA 3WCHA 4GP1A 4KFAA 3TS7A 5KSXF 1WL0A 3G4FA 1VG4A 3NRIA 1N22A 1N23A 1YYRA 3WCBA 4LLTA 5I1UA 1KIZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EWG A;  1YYT A;  3AQC B;  2Z52 A;  3IPI A;  1WKZ A;  4LTV A;  4LZC A;  1WMW A;  3VJD A;  3VJE A;  2Z7I A;  5DW7 A;  3SDQ A;  3IBA A;  3M00 A;  1YYS A;  2OPM A;  4NFK F;  5DJP F;  3VJ8 A;  3ID0 A;  2Z4W A;  4OGU A;  4LLS A;  5EAS A;  4KVD A;  3S4J A;  3WCE A;  1V4K A;  1VG3 A;  3MZV A;  1HXG A;  2E8W A;  3ZOU A;  1YYU A;  3N0F A;  5HN7 A;  2AEL A;  3PKO A;  2H8O A;  2F8C F;  3KRO B;  2OGD A;  4FJQ A;  5H9D A;  4RYP A;  5B0K A;  2ONG A;  5IL3 A;  5A0I A;  5E8H A;  2PS7 A;  1N24 A;  1RQJ A;  5IM1 A;  4FP4 A;  1DI1 A;  3LMD A;  3P8R A;  3LLW A;  5IKH A;  3DYG A;  3QKC A;  1UBV A;  1V4H A;  2F9K F;  3OAB B;  3WCG A;  3ACX A;  5B00 A;  5IK6 A;  3ICZ A;  3TC1 A;  4KK2 A;  1N21 A;  3LK5 A;  3EGT A;  2FTZ A;  5ILK A;  4EA2 A;  3VJC A;  2Z78 A;  2AEK A;  3RYW A;  1UBX A;  3WC9 A;  1KIY A;  2E8V A;  5B0J A;  5HN8 A;  3WEF A;  3WE9 A;  1HM4 A;  5JA0 F;  4JXN A;  4LPG F;  1ZW5 A;  5IL8 A;  3AQ0 A;  2E8X A;  1RTR A;  2E90 A;  2AZL A;  3N1W F;  3V66 A;  1N1B A;  3KRA B;  4LA5 A;  4LPH F;  4GA3 A;  3KRC A;  4KPD A;  3BNX A;  3PYB A;  1YJ4 A;  2QIS A;  4JXY A;  4P0V A;  4LIX A;  4H5C F;  4RXD A;  2FOR A;  2Z7H A;  3VJ9 A;  3ZCD A;  4F6V A;  3WEH A;  3B7L A;  1VG7 A;  3ICK A;  1HXA A;  4H5E F;  3M01 A;  5ILZ A;  1YV5 A;  3NPK A;  3KRP A;  4KQS A;  4XQR F;  3Q1O A;  3BNY A;  4F62 A;  5B0L A;  5ILD A;  3N49 F;  3KB9 A;  3AE0 A;  4QPF A;  3N0G A;  1WL1 A;  4EA1 A;  1WL2 A;  5DIQ F;  4F6X A;  5A0J A;  5DZ2 A;  4P0X A;  5IMI A;  3G4D A;  2Z4V A;  4RNQ A;  3OAC B;  3KRC B;  5E8L A;  3SDT A;  4OMH A;  3WCC A;  3WCJ A;  3WCM A;  3WCD A;  2ZEV A;  3ADZ A;  3RYE A;  4E9U A;  3V1X A;  5B0I A;  3LGZ B;  4MC8 A;  3LGK A;  3EFQ A;  5E8K A;  4MC3 A;  4OKZ A;  1JFA A;  2OPN A;  4UMJ A;  2Z4X A;  3N6K F;  3ICM A;  1HXC A;  2ZCO A;  3KRF A;  3ZL6 A;  3N45 F;  2RAH A;  5AHU B;  3WEG A;  2AET A;  4KQ5 A;  5IN8 A;  3M9U A;  4RXA A;  3TFP A;  3PDE A;  4LTZ A;  3LG5 A;  5IKA A;  3M0G A;  2O1O A;  5AFX A;  1HM7 A;  3N46 F;  3TFV A;  3DYH A;  2Z50 A;  2E93 A;  2AZK A;  1YQ7 A;  3SDV A;  5EAU A;  4L2X F;  4GAX A;  2F94 F;  3CP6 A;  4GP2 A;  4NUA A;  3W7F A;  1VG2 A;  5AYP A;  1WL3 A;  4K10 A;  3NPR A;  2F8Z F;  4NG6 A;  5JV2 F;  5ILI A;  4KQU A;  4JYX A;  2J1P A;  4PVY F;  2PS4 A;  3ICN A;  2J1O A;  2P1C A;  4DHD A;  3N3D A;  4WK5 A;  5A0K A;  2ZY1 A;  1WY0 A;  5IMP A;  5ILJ A;  4LUU A;  5DGM F;  2ZEU A;  3VJB A;  4JZX A;  3WCL A;  3ACY A;  4H5D F;  4LZ0 A;  3ZMB A;  2ZCS A;  3SAE A;  4E9Z A;  4KPJ A;  4NKE A;  2PS5 A;  4RXE A;  5ER8 A;  1UBW A;  3WJO A;  5IK0 A;  3APZ A;  3P41 A;  1YHL A;  4DI5 A;  5DHI A;  4MC0 A;  3KBK A;  3RBM A;  4KVW A;  4NKF A;  4LFG A;  4KKM A;  3RMG A;  1JFG A;  2Q58 A;  2ONH A;  2VF6 A;  3WEJ A;  4XQS F;  2F92 F;  2OA6 A;  4DEM F;  4EA0 A;  3Q30 A;  4JZB A;  3WEI A;  3M02 A;  4P0W A;  4LFV F;  1V4J A;  2E4O A;  3N5J F;  2E94 A;  5HN9 A;  3KRO A;  4KVI A;  3PYA A;  1HX9 A;  4LFE A;  4XQT F;  4QXS F;  3OYR A;  1EZF A;  3SDR A;  5HNA A;  3WJN A;  1YYQ A;  5ILY A;  4KVY A;  4LOB A;  5DGN F;  4DWG A;  5DJR F;  4DXJ A;  1V4I A;  3KRP B;  4KUX A;  2ZCQ A;  4N1Z F;  2E8T A;  3NF2 A;  3OAB A;  3N3L F;  3UCA A;  3VJA A;  1UBY A;  3WJK A;  3LZ9 A;  2E91 A;  5IMN A;  2PS6 A;  1N20 A;  5JV0 F;  3ASX A;  5C05 A;  1V4E A;  3TFN A;  4KWD A;  3WEK A;  3LSN A;  4OMG A;  2PS8 A;  5JUZ F;  4E1E A;  3LOM A;  3P5R A;  4JVJ F;  5IVG A;  3LVS A;  3N1V F;  5ERO A;  3P8L A;  3WCA A;  3LEE A;  4ZQ8 A;  3KRA A;  3WCF A;  2E92 A;  2I19 A;  3KRF B;  5DHK A;  2Z4Y A;  2ZCR A;  4NFI F;  3ACW A;  5B01 A;  5DJV F;  2Q9Y A;  3WSA A;  3LDW A;  3QQV A;  1N1Z A;  5IK9 A;  2Q80 A;  1VG6 A;  3MAV A;  3N5H F;  3LJI A;  5AEL A;  5CG6 A;  1RQI A;  3V1V A;  4PVX F;  5B03 A;  3PH7 A;  2E95 A;  4DWB A;  3EZ3 A;  3SDU A;  4Q23 A;  5CG5 A;  1FPS A;  5ERM A;  3DYF A;  2F89 F;  3ZMC A;  2J5C A;  5EAT A;  4LZ3 A;  5DGS F;  5B0M A;  3WSB A;  4NFJ F;  4OKM A;  3OAC A;  2F7M F;  4N9U A;  4LA6 A;  5JV1 F;  2Z4Z A;  3WCI A;  2AZJ A;  3AQB B;  4LXW A;  4RXC A;  2Q9Z A;  3CC9 A;  5B02 A;  3P5P A;  2E8U A;  3S9V A;  1YHM A;  4HD1 A;  3Q2Z A;  3CKE A;  5ILH A;  2DH4 A;  1PS1 A;  3Q2Q A;  4DZW A;  5ERN A;  1DGP A;  1YHK A;  3WCH A;  4GP1 A;  4KFA A;  3TS7 A;  5KSX F;  1WL0 A;  3G4F A;  1VG4 A;  3NRI A;  1N22 A;  1N23 A;  1YYR A;  3WCB A;  4LLT A;  5I1U A;  1KIZ A; 
#chains in the Genus database with same CATH topology
 2EWG A;  1YYT A;  3AQC B;  2Z52 A;  3IPI A;  1WKZ A;  4LTV A;  4LZC A;  1WMW A;  3VJD A;  3VJE A;  2Z7I A;  5DW7 A;  3SDQ A;  3IBA A;  3M00 A;  1YYS A;  2OPM A;  4NFK F;  5DJP F;  3VJ8 A;  3ID0 A;  2Z4W A;  4OGU A;  4LLS A;  5EAS A;  4KVD A;  3S4J A;  3WCE A;  1V4K A;  1VG3 A;  3MZV A;  1HXG A;  2E8W A;  3ZOU A;  1YYU A;  3N0F A;  5HN7 A;  2AEL A;  3PKO A;  2H8O A;  2F8C F;  3KRO B;  2OGD A;  4FJQ A;  5H9D A;  4RYP A;  5B0K A;  2ONG A;  5IL3 A;  5A0I A;  5E8H A;  2PS7 A;  1N24 A;  1RQJ A;  5IM1 A;  4FP4 A;  1DI1 A;  3LMD A;  3P8R A;  3LLW A;  5IKH A;  3DYG A;  3QKC A;  1UBV A;  1V4H A;  2F9K F;  3OAB B;  3WCG A;  3ACX A;  5B00 A;  5IK6 A;  3ICZ A;  3TC1 A;  4KK2 A;  1N21 A;  3LK5 A;  3EGT A;  2FTZ A;  5ILK A;  4EA2 A;  3VJC A;  2Z78 A;  2AEK A;  3RYW A;  1UBX A;  3WC9 A;  1KIY A;  2E8V A;  5B0J A;  5HN8 A;  3WEF A;  3WE9 A;  1HM4 A;  5JA0 F;  4JXN A;  4LPG F;  1ZW5 A;  5IL8 A;  3AQ0 A;  2E8X A;  1RTR A;  2E90 A;  2AZL A;  3N1W F;  3V66 A;  1N1B A;  3KRA B;  4LA5 A;  4LPH F;  4GA3 A;  3KRC A;  4KPD A;  3BNX A;  3PYB A;  1YJ4 A;  2QIS A;  4JXY A;  4P0V A;  4LIX A;  4H5C F;  4RXD A;  2FOR A;  2Z7H A;  3VJ9 A;  3ZCD A;  4F6V A;  3WEH A;  3B7L A;  1VG7 A;  3ICK A;  1HXA A;  4H5E F;  3M01 A;  5ILZ A;  1YV5 A;  3NPK A;  3KRP A;  4KQS A;  4XQR F;  3Q1O A;  3BNY A;  4F62 A;  5B0L A;  5ILD A;  3N49 F;  3KB9 A;  3AE0 A;  4QPF A;  3N0G A;  1WL1 A;  4EA1 A;  1WL2 A;  5DIQ F;  4F6X A;  5A0J A;  5DZ2 A;  4P0X A;  5IMI A;  3G4D A;  2Z4V A;  4RNQ A;  3OAC B;  3KRC B;  5E8L A;  3SDT A;  4OMH A;  3WCC A;  3WCJ A;  3WCM A;  3WCD A;  2ZEV A;  3ADZ A;  3RYE A;  4E9U A;  3V1X A;  5B0I A;  3LGZ B;  4MC8 A;  3LGK A;  3EFQ A;  5E8K A;  4MC3 A;  4OKZ A;  1JFA A;  2OPN A;  4UMJ A;  2Z4X A;  3N6K F;  3ICM A;  1HXC A;  2ZCO A;  3KRF A;  3ZL6 A;  3N45 F;  2RAH A;  5AHU B;  3WEG A;  2AET A;  4KQ5 A;  5IN8 A;  3M9U A;  4RXA A;  3TFP A;  3PDE A;  4LTZ A;  3LG5 A;  5IKA A;  3M0G A;  2O1O A;  5AFX A;  1HM7 A;  3N46 F;  3TFV A;  3DYH A;  2Z50 A;  2E93 A;  2AZK A;  1YQ7 A;  3SDV A;  5EAU A;  4L2X F;  4GAX A;  2F94 F;  3CP6 A;  4GP2 A;  4NUA A;  3W7F A;  1VG2 A;  5AYP A;  1WL3 A;  4K10 A;  3NPR A;  2F8Z F;  4NG6 A;  5JV2 F;  5ILI A;  4KQU A;  4JYX A;  2J1P A;  4PVY F;  2PS4 A;  3ICN A;  2J1O A;  2P1C A;  4DHD A;  3N3D A;  4WK5 A;  5A0K A;  2ZY1 A;  1WY0 A;  5IMP A;  5ILJ A;  4LUU A;  5DGM F;  2ZEU A;  3VJB A;  4JZX A;  3WCL A;  3ACY A;  4H5D F;  4LZ0 A;  3ZMB A;  2ZCS A;  3SAE A;  4E9Z A;  4KPJ A;  4NKE A;  2PS5 A;  4RXE A;  5ER8 A;  1UBW A;  3WJO A;  5IK0 A;  3APZ A;  3P41 A;  1YHL A;  4DI5 A;  5DHI A;  4MC0 A;  3KBK A;  3RBM A;  4KVW A;  4NKF A;  4LFG A;  4KKM A;  3RMG A;  1JFG A;  2Q58 A;  2ONH A;  2VF6 A;  3WEJ A;  4XQS F;  2F92 F;  2OA6 A;  4DEM F;  4EA0 A;  3Q30 A;  4JZB A;  3WEI A;  3M02 A;  4P0W A;  4LFV F;  1V4J A;  2E4O A;  3N5J F;  2E94 A;  5HN9 A;  3KRO A;  4KVI A;  3PYA A;  1HX9 A;  4LFE A;  4XQT F;  4QXS F;  3OYR A;  1EZF A;  3SDR A;  5HNA A;  3WJN A;  1YYQ A;  5ILY A;  4KVY A;  4LOB A;  5DGN F;  4DWG A;  5DJR F;  4DXJ A;  1V4I A;  3KRP B;  4KUX A;  2ZCQ A;  4N1Z F;  2E8T A;  3NF2 A;  3OAB A;  3N3L F;  3UCA A;  3VJA A;  1UBY A;  3WJK A;  3LZ9 A;  2E91 A;  5IMN A;  2PS6 A;  1N20 A;  5JV0 F;  3ASX A;  5C05 A;  1V4E A;  3TFN A;  4KWD A;  3WEK A;  3LSN A;  4OMG A;  2PS8 A;  5JUZ F;  4E1E A;  3LOM A;  3P5R A;  4JVJ F;  5IVG A;  3LVS A;  3N1V F;  5ERO A;  3P8L A;  3WCA A;  3LEE A;  4ZQ8 A;  3KRA A;  3WCF A;  2E92 A;  2I19 A;  3KRF B;  5DHK A;  2Z4Y A;  2ZCR A;  4NFI F;  3ACW A;  5B01 A;  5DJV F;  2Q9Y A;  3WSA A;  3LDW A;  3QQV A;  1N1Z A;  5IK9 A;  2Q80 A;  1VG6 A;  3MAV A;  3N5H F;  3LJI A;  5AEL A;  5CG6 A;  1RQI A;  3V1V A;  4PVX F;  5B03 A;  3PH7 A;  2E95 A;  4DWB A;  3EZ3 A;  3SDU A;  4Q23 A;  5CG5 A;  1FPS A;  5ERM A;  3DYF A;  2F89 F;  3ZMC A;  2J5C A;  5EAT A;  4LZ3 A;  5DGS F;  5B0M A;  3WSB A;  4NFJ F;  4OKM A;  3OAC A;  2F7M F;  4N9U A;  4LA6 A;  5JV1 F;  2Z4Z A;  3WCI A;  2AZJ A;  3AQB B;  4LXW A;  4RXC A;  2Q9Z A;  3CC9 A;  5B02 A;  3P5P A;  2E8U A;  3S9V A;  1YHM A;  4HD1 A;  3Q2Z A;  3CKE A;  5ILH A;  2DH4 A;  1PS1 A;  3Q2Q A;  4DZW A;  5ERN A;  1DGP A;  1YHK A;  3WCH A;  4GP1 A;  4KFA A;  3TS7 A;  5KSX F;  1WL0 A;  3G4F A;  1VG4 A;  3NRI A;  1N22 A;  1N23 A;  1YYR A;  3WCB A;  4LLT A;  5I1U A;  1KIZ A; 
#chains in the Genus database with same CATH homology
 2EWG A;  1YYT A;  3AQC B;  2Z52 A;  3IPI A;  1WKZ A;  4LTV A;  4LZC A;  1WMW A;  3VJD A;  3VJE A;  2Z7I A;  5DW7 A;  3SDQ A;  3IBA A;  3M00 A;  1YYS A;  2OPM A;  4NFK F;  5DJP F;  3VJ8 A;  3ID0 A;  2Z4W A;  4OGU A;  4LLS A;  5EAS A;  4KVD A;  3S4J A;  3WCE A;  1V4K A;  1VG3 A;  3MZV A;  1HXG A;  2E8W A;  3ZOU A;  1YYU A;  3N0F A;  5HN7 A;  2AEL A;  3PKO A;  2H8O A;  2F8C F;  3KRO B;  2OGD A;  4FJQ A;  5H9D A;  4RYP A;  5B0K A;  2ONG A;  5IL3 A;  5A0I A;  5E8H A;  2PS7 A;  1N24 A;  1RQJ A;  5IM1 A;  4FP4 A;  1DI1 A;  3LMD A;  3P8R A;  3LLW A;  5IKH A;  3DYG A;  3QKC A;  1UBV A;  1V4H A;  2F9K F;  3OAB B;  3WCG A;  3ACX A;  5B00 A;  5IK6 A;  3ICZ A;  3TC1 A;  4KK2 A;  1N21 A;  3LK5 A;  3EGT A;  2FTZ A;  5ILK A;  4EA2 A;  3VJC A;  2Z78 A;  2AEK A;  3RYW A;  1UBX A;  3WC9 A;  1KIY A;  2E8V A;  5B0J A;  5HN8 A;  3WEF A;  3WE9 A;  1HM4 A;  5JA0 F;  4JXN A;  4LPG F;  1ZW5 A;  5IL8 A;  3AQ0 A;  2E8X A;  1RTR A;  2E90 A;  2AZL A;  3N1W F;  3V66 A;  1N1B A;  3KRA B;  4LA5 A;  4LPH F;  4GA3 A;  3KRC A;  4KPD A;  3BNX A;  3PYB A;  1YJ4 A;  2QIS A;  4JXY A;  4P0V A;  4LIX A;  4H5C F;  4RXD A;  2FOR A;  2Z7H A;  3VJ9 A;  3ZCD A;  4F6V A;  3WEH A;  3B7L A;  1VG7 A;  3ICK A;  1HXA A;  4H5E F;  3M01 A;  5ILZ A;  1YV5 A;  3NPK A;  3KRP A;  4KQS A;  4XQR F;  3Q1O A;  3BNY A;  4F62 A;  5B0L A;  5ILD A;  3N49 F;  3KB9 A;  3AE0 A;  4QPF A;  3N0G A;  1WL1 A;  4EA1 A;  1WL2 A;  5DIQ F;  4F6X A;  5A0J A;  5DZ2 A;  4P0X A;  5IMI A;  3G4D A;  2Z4V A;  4RNQ A;  3OAC B;  3KRC B;  5E8L A;  3SDT A;  4OMH A;  3WCC A;  3WCJ A;  3WCM A;  3WCD A;  2ZEV A;  3ADZ A;  3RYE A;  4E9U A;  3V1X A;  5B0I A;  3LGZ B;  4MC8 A;  3LGK A;  3EFQ A;  5E8K A;  4MC3 A;  4OKZ A;  1JFA A;  2OPN A;  4UMJ A;  2Z4X A;  3N6K F;  3ICM A;  1HXC A;  2ZCO A;  3KRF A;  3ZL6 A;  3N45 F;  2RAH A;  5AHU B;  3WEG A;  2AET A;  4KQ5 A;  5IN8 A;  3M9U A;  4RXA A;  3TFP A;  3PDE A;  4LTZ A;  3LG5 A;  5IKA A;  3M0G A;  2O1O A;  5AFX A;  1HM7 A;  3N46 F;  3TFV A;  3DYH A;  2Z50 A;  2E93 A;  2AZK A;  1YQ7 A;  3SDV A;  5EAU A;  4L2X F;  4GAX A;  2F94 F;  3CP6 A;  4GP2 A;  4NUA A;  3W7F A;  1VG2 A;  5AYP A;  1WL3 A;  4K10 A;  3NPR A;  2F8Z F;  4NG6 A;  5JV2 F;  5ILI A;  4KQU A;  4JYX A;  2J1P A;  4PVY F;  2PS4 A;  3ICN A;  2J1O A;  2P1C A;  4DHD A;  3N3D A;  4WK5 A;  5A0K A;  2ZY1 A;  1WY0 A;  5IMP A;  5ILJ A;  4LUU A;  5DGM F;  2ZEU A;  3VJB A;  4JZX A;  3WCL A;  3ACY A;  4H5D F;  4LZ0 A;  3ZMB A;  2ZCS A;  3SAE A;  4E9Z A;  4KPJ A;  4NKE A;  2PS5 A;  4RXE A;  5ER8 A;  1UBW A;  3WJO A;  5IK0 A;  3APZ A;  3P41 A;  1YHL A;  4DI5 A;  5DHI A;  4MC0 A;  3KBK A;  3RBM A;  4KVW A;  4NKF A;  4LFG A;  4KKM A;  3RMG A;  1JFG A;  2Q58 A;  2ONH A;  2VF6 A;  3WEJ A;  4XQS F;  2F92 F;  2OA6 A;  4DEM F;  4EA0 A;  3Q30 A;  4JZB A;  3WEI A;  3M02 A;  4P0W A;  4LFV F;  1V4J A;  2E4O A;  3N5J F;  2E94 A;  5HN9 A;  3KRO A;  4KVI A;  3PYA A;  1HX9 A;  4LFE A;  4XQT F;  4QXS F;  3OYR A;  1EZF A;  3SDR A;  5HNA A;  3WJN A;  1YYQ A;  5ILY A;  4KVY A;  4LOB A;  5DGN F;  4DWG A;  5DJR F;  4DXJ A;  1V4I A;  3KRP B;  4KUX A;  2ZCQ A;  4N1Z F;  2E8T A;  3NF2 A;  3OAB A;  3N3L F;  3UCA A;  3VJA A;  1UBY A;  3WJK A;  3LZ9 A;  2E91 A;  5IMN A;  2PS6 A;  1N20 A;  5JV0 F;  3ASX A;  5C05 A;  1V4E A;  3TFN A;  4KWD A;  3WEK A;  3LSN A;  4OMG A;  2PS8 A;  5JUZ F;  4E1E A;  3LOM A;  3P5R A;  4JVJ F;  5IVG A;  3LVS A;  3N1V F;  5ERO A;  3P8L A;  3WCA A;  3LEE A;  4ZQ8 A;  3KRA A;  3WCF A;  2E92 A;  2I19 A;  3KRF B;  5DHK A;  2Z4Y A;  2ZCR A;  4NFI F;  3ACW A;  5B01 A;  5DJV F;  2Q9Y A;  3WSA A;  3LDW A;  3QQV A;  1N1Z A;  5IK9 A;  2Q80 A;  1VG6 A;  3MAV A;  3N5H F;  3LJI A;  5AEL A;  5CG6 A;  1RQI A;  3V1V A;  4PVX F;  5B03 A;  3PH7 A;  2E95 A;  4DWB A;  3EZ3 A;  3SDU A;  4Q23 A;  5CG5 A;  1FPS A;  5ERM A;  3DYF A;  2F89 F;  3ZMC A;  2J5C A;  5EAT A;  4LZ3 A;  5DGS F;  5B0M A;  3WSB A;  4NFJ F;  4OKM A;  3OAC A;  2F7M F;  4N9U A;  4LA6 A;  5JV1 F;  2Z4Z A;  3WCI A;  2AZJ A;  3AQB B;  4LXW A;  4RXC A;  2Q9Z A;  3CC9 A;  5B02 A;  3P5P A;  2E8U A;  3S9V A;  1YHM A;  4HD1 A;  3Q2Z A;  3CKE A;  5ILH A;  2DH4 A;  1PS1 A;  3Q2Q A;  4DZW A;  5ERN A;  1DGP A;  1YHK A;  3WCH A;  4GP1 A;  4KFA A;  3TS7 A;  5KSX F;  1WL0 A;  3G4F A;  1VG4 A;  3NRI A;  1N22 A;  1N23 A;  1YYR A;  3WCB A;  4LLT A;  5I1U A;  1KIZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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