3VJ8A

Crystal structure of the human squalene synthase
Total Genus 144
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
144
sequence length
335
structure length
335
Chain Sequence
SLSSSLKTCYKYLNQTSRSFAAVIQALDGEMRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTISLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Squalene synthase
total genus 144
structure length 335
sequence length 335
ec nomenclature ec 2.5.1.21: Squalene synthase.
pdb deposition date 2011-10-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00494 SQS_PSY Squalene/phytoene synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.600.10 Mainly Alpha Orthogonal Bundle Farnesyl Diphosphate Synthase Farnesyl Diphosphate Synthase 3vj8A00
4UMJA 1V4IA 1WL2A 2VF6A 1N1BA 4RXEA 3P8RA 3KRCB 4EA2A 3WCAA 1UBXA 5ILIA 3LZ9A 3LMDA 3NRIA 4LPGF 3WEGA 3WSAA 4NKEA 4KQUA 3VJEA 3KRFA 3Q30A 4GA3A 5IN8A 3AE0A 3S4JA 5ILJA 5C05A 3SAEA 3N5JF 2PS7A 4GP2A 2F92F 3TC1A 3WEJA 2O1OA 3LGZB 5JV1F 1YQ7A 4LOBA 3WEHA 4DI5A 4JYXA 5CG5A 4ZQ8A 3M01A 3OABB 3G4DA 3QQVA 3WEKA 4LZ3A 3V1XA 5B0IA 2OPNA 2E90A 1WKZA 3WCDA 4QXSF 3ASXA 5HN7A 3WCJA 5ILKA 4NUAA 2Q58A 4RXAA 3KBKA 5ILZA 3KRCA 5EATA 4P0XA 2F7MF 3M9UA 4DXJA 4JXYA 3VJ8A 2E8VA 3N1VF 5H9DA 5AHUB 3WCMA 2J1OA 3VJBA 4EA1A 3Q2QA 5DJVF 5A0KA 4P0VA 3EFQA 1DGPA 1WL3A 3IPIA 3PKOA 2ZCSA 4KPJA 3Q2ZA 4RXDA 3P41A 3AQ0A 3ACXA 4H5DF 3UCAA 1HXGA 3OYRA 3OABA 3CP6A 2E94A 4Q23A 1YYQA 3P8LA 3ZCDA 3VJAA 2E93A 3OACA 4LPHF 5DJPF 5DW7A 5ERMA 4GP1A 3WCIA 1JFAA 4KWDA 5ILDA 4E9UA 3AQCB 4LLSA 2F8ZF 4OGUA 5IL8A 3P5PA 2AETA 3V66A 3RYEA 2Z78A 5ER8A 4LTZA 4OKMA 3W7FA 3WCGA 4EA0A 3N46F 3G4FA 3PDEA 5DIQF 3N3DA 3WJKA 4LFVF 1KIYA 5HNAA 1VG7A 2PS4A 4XQTF 1WL1A 3DYFA 3N0FA 5DGMF 2F9KF 4DZWA 3WC9A 5AFXA 4NG6A 5JV2F 3N45F 3M02A 3SDQA 3ZL6A 3P5RA 3LK5A 2EWGA 5ERNA 3ACWA 3KRAB 1WMWA 2E4OA 3RBMA 1YYSA 3NPRA 2P1CA 3ACYA 3SDTA 3N49F 2FORA 4HD1A 2J1PA 1HM7A 4F62A 3EZ3A 4WK5A 5DHKA 3V1VA 5IVGA 2Z52A 5HN8A 2Q80A 3CC9A 4LA6A 2Z4YA 2AZKA 4LZCA 4N1ZF 3WCFA 3ADZA 4F6XA 1ZW5A 2Z4WA 4QPFA 3WCCA 3KRPB 2FTZA 3Q1OA 5B00A 3ID0A 4NFJF 2AELA 5IM1A 3M0GA 4JVJF 4F6VA 5KSXF 2Z7IA 3ZMCA 2ZCRA 2E8TA 5E8LA 2DH4A 3WJNA 5IK9A 1EZFA 4KVWA 4DHDA 4PVYF 3KRAA 3WCHA 2PS6A 1V4EA 3LLWA 1UBVA 4K10A 3WEFA 3SDUA 4XQSF 5B03A 1HXAA 2E8WA 2I19A 2Q9YA 3N5HF 1HM4A 3TFPA 4KVYA 5DGSF 2AZLA 1VG2A 1HX9A 1RQJA 5IL3A 3BNXA 3TFVA 2J5CA 2E91A 3ZOUA 3LVSA 3PYBA 3NPKA 3AQBB 2AZJA 4JXNA 4LTVA 3WJOA 5DJRF 1V4JA 1PS1A 4LUUA 1RQIA 4XQRF 1YJ4A 3RYWA 4PVXF 3MAVA 5IK6A 5DZ2A 2ZCOA 1V4KA 3ICZA 3N6KF 5JUZF 5AELA 3LEEA 5I1UA 2E8XA 3PYAA 3VJCA 1N1ZA 4JZBA 1DI1A 5A0JA 5B0LA 4NFIF 4DWGA 3CKEA 4NFKF 4MC8A 1YHKA 2ONHA 4MC0A 4GAXA 2RAHA 3LOMA 1VG4A 3B7LA 3WE9A 4KK2A 3PH7A 5IK0A 4KPDA 1YYRA 3N1WF 3VJ9A 4DWBA 5B0KA 1KIZA 4FJQA 1FPSA 5EAUA 5CG6A 4N9UA 2E92A 3IBAA 3S9VA 3TFNA 1N22A 3KROB 2F8CF 3WSBA 4E9ZA 3N3LF 2OPMA 4LFEA 4KVIA 1N23A 4MC3A 4LFGA 3BNYA 2ZEUA 4NKFA 5B0MA 3SDRA 5EROA 1N21A 1WL0A 4KKMA 2Q9ZA 4L2XF 5ILYA 5JA0F 3WCEA 2PS5A 2QISA 3ICMA 1UBYA 5E8KA 3EGTA 2Z50A 2Z7HA 3OACB 3ICNA 4DEMF 1YYTA 3WEIA 3DYGA 2ZCQA 3RMGA 5A0IA 3ZMBA 3LGKA 5B0JA 4JZXA 4OKZA 2ONGA 5AYPA 2E8UA 1JFGA 1UBWA 4H5EF 5ILHA 3VJDA 5B01A 3MZVA 4RNQA 4E1EA 1HXCA 1VG3A 1YHMA 1N20A 3KROA 3LJIA 3KRPA 3ICKA 4LXWA 4RXCA 3WCBA 1YHLA 4KFAA 3LSNA 3APZA 5DHIA 4LZ0A 4H5CF 3DYHA 5HN9A 4KUXA 4RYPA 4FP4A 1YYUA 2Z4VA 5DGNF 2AEKA 2E95A 2OGDA 3QKCA 5JV0F 5EASA 1WY0A 1V4HA 5IMIA 1RTRA 3KB9A 4P0WA 3KRFB 2PS8A 3LG5A 4KQ5A 2OA6A 2F89F 2H8OA 5IMPA 2ZEVA 3NF2A 4KQSA 4KVDA 4OMHA 3TS7A 5B02A 4LLTA 5IMNA 3SDVA 5IKHA 3LDWA 4LIXA 2Z4XA 3N0GA 5IKAA 3WCLA 4OMGA 4LA5A 1N24A 1VG6A 1YV5A 2Z4ZA 2ZY1A 2F94F 3M00A 5E8HA
chains in the Genus database with same CATH superfamily
4UMJA 1V4IA 1WL2A 2VF6A 1N1BA 4RXEA 3P8RA 3KRCB 4EA2A 3WCAA 1UBXA 5ILIA 3LZ9A 3LMDA 3NRIA 4LPGF 3WEGA 3WSAA 4NKEA 4KQUA 3VJEA 3KRFA 3Q30A 4GA3A 5IN8A 3AE0A 3S4JA 5ILJA 5C05A 3SAEA 3N5JF 2PS7A 4GP2A 2F92F 3TC1A 3WEJA 2O1OA 3LGZB 5JV1F 1YQ7A 4LOBA 3WEHA 4DI5A 4JYXA 5CG5A 4ZQ8A 3M01A 3OABB 3G4DA 3QQVA 3WEKA 4LZ3A 3V1XA 5B0IA 2OPNA 2E90A 1WKZA 3WCDA 4QXSF 3ASXA 5HN7A 3WCJA 5ILKA 4NUAA 2Q58A 4RXAA 3KBKA 5ILZA 3KRCA 5EATA 4P0XA 2F7MF 3M9UA 4DXJA 4JXYA 3VJ8A 2E8VA 3N1VF 5H9DA 5AHUB 3WCMA 2J1OA 3VJBA 4EA1A 3Q2QA 5DJVF 5A0KA 4P0VA 3EFQA 1DGPA 1WL3A 3IPIA 3PKOA 2ZCSA 4KPJA 3Q2ZA 4RXDA 3P41A 3AQ0A 3ACXA 4H5DF 3UCAA 1HXGA 3OYRA 3OABA 3CP6A 2E94A 4Q23A 1YYQA 3P8LA 3ZCDA 3VJAA 2E93A 3OACA 4LPHF 5DJPF 5DW7A 5ERMA 4GP1A 3WCIA 1JFAA 4KWDA 5ILDA 4E9UA 3AQCB 4LLSA 2F8ZF 4OGUA 5IL8A 3P5PA 2AETA 3V66A 3RYEA 2Z78A 5ER8A 4LTZA 4OKMA 3W7FA 3WCGA 4EA0A 3N46F 3G4FA 3PDEA 5DIQF 3N3DA 3WJKA 4LFVF 1KIYA 5HNAA 1VG7A 2PS4A 4XQTF 1WL1A 3DYFA 3N0FA 5DGMF 2F9KF 4DZWA 3WC9A 5AFXA 4NG6A 5JV2F 3N45F 3M02A 3SDQA 3ZL6A 3P5RA 3LK5A 2EWGA 5ERNA 3ACWA 3KRAB 1WMWA 2E4OA 3RBMA 1YYSA 3NPRA 2P1CA 3ACYA 3SDTA 3N49F 2FORA 4HD1A 2J1PA 1HM7A 4F62A 3EZ3A 4WK5A 5DHKA 3V1VA 5IVGA 2Z52A 5HN8A 2Q80A 3CC9A 4LA6A 2Z4YA 2AZKA 4LZCA 4N1ZF 3WCFA 3ADZA 4F6XA 1ZW5A 2Z4WA 4QPFA 3WCCA 3KRPB 2FTZA 3Q1OA 5B00A 3ID0A 4NFJF 2AELA 5IM1A 3M0GA 4JVJF 4F6VA 5KSXF 2Z7IA 3ZMCA 2ZCRA 2E8TA 5E8LA 2DH4A 3WJNA 5IK9A 1EZFA 4KVWA 4DHDA 4PVYF 3KRAA 3WCHA 2PS6A 1V4EA 3LLWA 1UBVA 4K10A 3WEFA 3SDUA 4XQSF 5B03A 1HXAA 2E8WA 2I19A 2Q9YA 3N5HF 1HM4A 3TFPA 4KVYA 5DGSF 2AZLA 1VG2A 1HX9A 1RQJA 5IL3A 3BNXA 3TFVA 2J5CA 2E91A 3ZOUA 3LVSA 3PYBA 3NPKA 3AQBB 2AZJA 4JXNA 4LTVA 3WJOA 5DJRF 1V4JA 1PS1A 4LUUA 1RQIA 4XQRF 1YJ4A 3RYWA 4PVXF 3MAVA 5IK6A 5DZ2A 2ZCOA 1V4KA 3ICZA 3N6KF 5JUZF 5AELA 3LEEA 5I1UA 2E8XA 3PYAA 3VJCA 1N1ZA 4JZBA 1DI1A 5A0JA 5B0LA 4NFIF 4DWGA 3CKEA 4NFKF 4MC8A 1YHKA 2ONHA 4MC0A 4GAXA 2RAHA 3LOMA 1VG4A 3B7LA 3WE9A 4KK2A 3PH7A 5IK0A 4KPDA 1YYRA 3N1WF 3VJ9A 4DWBA 5B0KA 1KIZA 4FJQA 1FPSA 5EAUA 5CG6A 4N9UA 2E92A 3IBAA 3S9VA 3TFNA 1N22A 3KROB 2F8CF 3WSBA 4E9ZA 3N3LF 2OPMA 4LFEA 4KVIA 1N23A 4MC3A 4LFGA 3BNYA 2ZEUA 4NKFA 5B0MA 3SDRA 5EROA 1N21A 1WL0A 4KKMA 2Q9ZA 4L2XF 5ILYA 5JA0F 3WCEA 2PS5A 2QISA 3ICMA 1UBYA 5E8KA 3EGTA 2Z50A 2Z7HA 3OACB 3ICNA 4DEMF 1YYTA 3WEIA 3DYGA 2ZCQA 3RMGA 5A0IA 3ZMBA 3LGKA 5B0JA 4JZXA 4OKZA 2ONGA 5AYPA 2E8UA 1JFGA 1UBWA 4H5EF 5ILHA 3VJDA 5B01A 3MZVA 4RNQA 4E1EA 1HXCA 1VG3A 1YHMA 1N20A 3KROA 3LJIA 3KRPA 3ICKA 4LXWA 4RXCA 3WCBA 1YHLA 4KFAA 3LSNA 3APZA 5DHIA 4LZ0A 4H5CF 3DYHA 5HN9A 4KUXA 4RYPA 4FP4A 1YYUA 2Z4VA 5DGNF 2AEKA 2E95A 2OGDA 3QKCA 5JV0F 5EASA 1WY0A 1V4HA 5IMIA 1RTRA 3KB9A 4P0WA 3KRFB 2PS8A 3LG5A 4KQ5A 2OA6A 2F89F 2H8OA 5IMPA 2ZEVA 3NF2A 4KQSA 4KVDA 4OMHA 3TS7A 5B02A 4LLTA 5IMNA 3SDVA 5IKHA 3LDWA 4LIXA 2Z4XA 3N0GA 5IKAA 3WCLA 4OMGA 4LA5A 1N24A 1VG6A 1YV5A 2Z4ZA 2ZY1A 2F94F 3M00A 5E8HA
chains in the Genus database with same CATH topology
4UMJA 1V4IA 1WL2A 2VF6A 1N1BA 4RXEA 3P8RA 3KRCB 4EA2A 3WCAA 1UBXA 5ILIA 3LZ9A 3LMDA 3NRIA 4LPGF 3WEGA 3WSAA 4NKEA 4KQUA 3VJEA 3KRFA 3Q30A 4GA3A 5IN8A 3AE0A 3S4JA 5ILJA 5C05A 3SAEA 3N5JF 2PS7A 4GP2A 2F92F 3TC1A 3WEJA 2O1OA 3LGZB 5JV1F 1YQ7A 4LOBA 3WEHA 4DI5A 4JYXA 5CG5A 4ZQ8A 3M01A 3OABB 3G4DA 3QQVA 3WEKA 4LZ3A 3V1XA 5B0IA 2OPNA 2E90A 1WKZA 3WCDA 4QXSF 3ASXA 5HN7A 3WCJA 5ILKA 4NUAA 2Q58A 4RXAA 3KBKA 5ILZA 3KRCA 5EATA 4P0XA 2F7MF 3M9UA 4DXJA 4JXYA 3VJ8A 2E8VA 3N1VF 5H9DA 5AHUB 3WCMA 2J1OA 3VJBA 4EA1A 3Q2QA 5DJVF 5A0KA 4P0VA 3EFQA 1DGPA 1WL3A 3IPIA 3PKOA 2ZCSA 4KPJA 3Q2ZA 4RXDA 3P41A 3AQ0A 3ACXA 4H5DF 3UCAA 1HXGA 3OYRA 3OABA 3CP6A 2E94A 4Q23A 1YYQA 3P8LA 3ZCDA 3VJAA 2E93A 3OACA 4LPHF 5DJPF 5DW7A 5ERMA 4GP1A 3WCIA 1JFAA 4KWDA 5ILDA 4E9UA 3AQCB 4LLSA 2F8ZF 4OGUA 5IL8A 3P5PA 2AETA 3V66A 3RYEA 2Z78A 5ER8A 4LTZA 4OKMA 3W7FA 3WCGA 4EA0A 3N46F 3G4FA 3PDEA 5DIQF 3N3DA 3WJKA 4LFVF 1KIYA 5HNAA 1VG7A 2PS4A 4XQTF 1WL1A 3DYFA 3N0FA 5DGMF 2F9KF 4DZWA 3WC9A 5AFXA 4NG6A 5JV2F 3N45F 3M02A 3SDQA 3ZL6A 3P5RA 3LK5A 2EWGA 5ERNA 3ACWA 3KRAB 1WMWA 2E4OA 3RBMA 1YYSA 3NPRA 2P1CA 3ACYA 3SDTA 3N49F 2FORA 4HD1A 2J1PA 1HM7A 4F62A 3EZ3A 4WK5A 5DHKA 3V1VA 5IVGA 2Z52A 5HN8A 2Q80A 3CC9A 4LA6A 2Z4YA 2AZKA 4LZCA 4N1ZF 3WCFA 3ADZA 4F6XA 1ZW5A 2Z4WA 4QPFA 3WCCA 3KRPB 2FTZA 3Q1OA 5B00A 3ID0A 4NFJF 2AELA 5IM1A 3M0GA 4JVJF 4F6VA 5KSXF 2Z7IA 3ZMCA 2ZCRA 2E8TA 5E8LA 2DH4A 3WJNA 5IK9A 1EZFA 4KVWA 4DHDA 4PVYF 3KRAA 3WCHA 2PS6A 1V4EA 3LLWA 1UBVA 4K10A 3WEFA 3SDUA 4XQSF 5B03A 1HXAA 2E8WA 2I19A 2Q9YA 3N5HF 1HM4A 3TFPA 4KVYA 5DGSF 2AZLA 1VG2A 1HX9A 1RQJA 5IL3A 3BNXA 3TFVA 2J5CA 2E91A 3ZOUA 3LVSA 3PYBA 3NPKA 3AQBB 2AZJA 4JXNA 4LTVA 3WJOA 5DJRF 1V4JA 1PS1A 4LUUA 1RQIA 4XQRF 1YJ4A 3RYWA 4PVXF 3MAVA 5IK6A 5DZ2A 2ZCOA 1V4KA 3ICZA 3N6KF 5JUZF 5AELA 3LEEA 5I1UA 2E8XA 3PYAA 3VJCA 1N1ZA 4JZBA 1DI1A 5A0JA 5B0LA 4NFIF 4DWGA 3CKEA 4NFKF 4MC8A 1YHKA 2ONHA 4MC0A 4GAXA 2RAHA 3LOMA 1VG4A 3B7LA 3WE9A 4KK2A 3PH7A 5IK0A 4KPDA 1YYRA 3N1WF 3VJ9A 4DWBA 5B0KA 1KIZA 4FJQA 1FPSA 5EAUA 5CG6A 4N9UA 2E92A 3IBAA 3S9VA 3TFNA 1N22A 3KROB 2F8CF 3WSBA 4E9ZA 3N3LF 2OPMA 4LFEA 4KVIA 1N23A 4MC3A 4LFGA 3BNYA 2ZEUA 4NKFA 5B0MA 3SDRA 5EROA 1N21A 1WL0A 4KKMA 2Q9ZA 4L2XF 5ILYA 5JA0F 3WCEA 2PS5A 2QISA 3ICMA 1UBYA 5E8KA 3EGTA 2Z50A 2Z7HA 3OACB 3ICNA 4DEMF 1YYTA 3WEIA 3DYGA 2ZCQA 3RMGA 5A0IA 3ZMBA 3LGKA 5B0JA 4JZXA 4OKZA 2ONGA 5AYPA 2E8UA 1JFGA 1UBWA 4H5EF 5ILHA 3VJDA 5B01A 3MZVA 4RNQA 4E1EA 1HXCA 1VG3A 1YHMA 1N20A 3KROA 3LJIA 3KRPA 3ICKA 4LXWA 4RXCA 3WCBA 1YHLA 4KFAA 3LSNA 3APZA 5DHIA 4LZ0A 4H5CF 3DYHA 5HN9A 4KUXA 4RYPA 4FP4A 1YYUA 2Z4VA 5DGNF 2AEKA 2E95A 2OGDA 3QKCA 5JV0F 5EASA 1WY0A 1V4HA 5IMIA 1RTRA 3KB9A 4P0WA 3KRFB 2PS8A 3LG5A 4KQ5A 2OA6A 2F89F 2H8OA 5IMPA 2ZEVA 3NF2A 4KQSA 4KVDA 4OMHA 3TS7A 5B02A 4LLTA 5IMNA 3SDVA 5IKHA 3LDWA 4LIXA 2Z4XA 3N0GA 5IKAA 3WCLA 4OMGA 4LA5A 1N24A 1VG6A 1YV5A 2Z4ZA 2ZY1A 2F94F 3M00A 5E8HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UMJ A;  1V4I A;  1WL2 A;  2VF6 A;  1N1B A;  4RXE A;  3P8R A;  3KRC B;  4EA2 A;  3WCA A;  1UBX A;  5ILI A;  3LZ9 A;  3LMD A;  3NRI A;  4LPG F;  3WEG A;  3WSA A;  4NKE A;  4KQU A;  3VJE A;  3KRF A;  3Q30 A;  4GA3 A;  5IN8 A;  3AE0 A;  3S4J A;  5ILJ A;  5C05 A;  3SAE A;  3N5J F;  2PS7 A;  4GP2 A;  2F92 F;  3TC1 A;  3WEJ A;  2O1O A;  3LGZ B;  5JV1 F;  1YQ7 A;  4LOB A;  3WEH A;  4DI5 A;  4JYX A;  5CG5 A;  4ZQ8 A;  3M01 A;  3OAB B;  3G4D A;  3QQV A;  3WEK A;  4LZ3 A;  3V1X A;  5B0I A;  2OPN A;  2E90 A;  1WKZ A;  3WCD A;  4QXS F;  3ASX A;  5HN7 A;  3WCJ A;  5ILK A;  4NUA A;  2Q58 A;  4RXA A;  3KBK A;  5ILZ A;  3KRC A;  5EAT A;  4P0X A;  2F7M F;  3M9U A;  4DXJ A;  4JXY A;  3VJ8 A;  2E8V A;  3N1V F;  5H9D A;  5AHU B;  3WCM A;  2J1O A;  3VJB A;  4EA1 A;  3Q2Q A;  5DJV F;  5A0K A;  4P0V A;  3EFQ A;  1DGP A;  1WL3 A;  3IPI A;  3PKO A;  2ZCS A;  4KPJ A;  3Q2Z A;  4RXD A;  3P41 A;  3AQ0 A;  3ACX A;  4H5D F;  3UCA A;  1HXG A;  3OYR A;  3OAB A;  3CP6 A;  2E94 A;  4Q23 A;  1YYQ A;  3P8L A;  3ZCD A;  3VJA A;  2E93 A;  3OAC A;  4LPH F;  5DJP F;  5DW7 A;  5ERM A;  4GP1 A;  3WCI A;  1JFA A;  4KWD A;  5ILD A;  4E9U A;  3AQC B;  4LLS A;  2F8Z F;  4OGU A;  5IL8 A;  3P5P A;  2AET A;  3V66 A;  3RYE A;  2Z78 A;  5ER8 A;  4LTZ A;  4OKM A;  3W7F A;  3WCG A;  4EA0 A;  3N46 F;  3G4F A;  3PDE A;  5DIQ F;  3N3D A;  3WJK A;  4LFV F;  1KIY A;  5HNA A;  1VG7 A;  2PS4 A;  4XQT F;  1WL1 A;  3DYF A;  3N0F A;  5DGM F;  2F9K F;  4DZW A;  3WC9 A;  5AFX A;  4NG6 A;  5JV2 F;  3N45 F;  3M02 A;  3SDQ A;  3ZL6 A;  3P5R A;  3LK5 A;  2EWG A;  5ERN A;  3ACW A;  3KRA B;  1WMW A;  2E4O A;  3RBM A;  1YYS A;  3NPR A;  2P1C A;  3ACY A;  3SDT A;  3N49 F;  2FOR A;  4HD1 A;  2J1P A;  1HM7 A;  4F62 A;  3EZ3 A;  4WK5 A;  5DHK A;  3V1V A;  5IVG A;  2Z52 A;  5HN8 A;  2Q80 A;  3CC9 A;  4LA6 A;  2Z4Y A;  2AZK A;  4LZC A;  4N1Z F;  3WCF A;  3ADZ A;  4F6X A;  1ZW5 A;  2Z4W A;  4QPF A;  3WCC A;  3KRP B;  2FTZ A;  3Q1O A;  5B00 A;  3ID0 A;  4NFJ F;  2AEL A;  5IM1 A;  3M0G A;  4JVJ F;  4F6V A;  5KSX F;  2Z7I A;  3ZMC A;  2ZCR A;  2E8T A;  5E8L A;  2DH4 A;  3WJN A;  5IK9 A;  1EZF A;  4KVW A;  4DHD A;  4PVY F;  3KRA A;  3WCH A;  2PS6 A;  1V4E A;  3LLW A;  1UBV A;  4K10 A;  3WEF A;  3SDU A;  4XQS F;  5B03 A;  1HXA A;  2E8W A;  2I19 A;  2Q9Y A;  3N5H F;  1HM4 A;  3TFP A;  4KVY A;  5DGS F;  2AZL A;  1VG2 A;  1HX9 A;  1RQJ A;  5IL3 A;  3BNX A;  3TFV A;  2J5C A;  2E91 A;  3ZOU A;  3LVS A;  3PYB A;  3NPK A;  3AQB B;  2AZJ A;  4JXN A;  4LTV A;  3WJO A;  5DJR F;  1V4J A;  1PS1 A;  4LUU A;  1RQI A;  4XQR F;  1YJ4 A;  3RYW A;  4PVX F;  3MAV A;  5IK6 A;  5DZ2 A;  2ZCO A;  1V4K A;  3ICZ A;  3N6K F;  5JUZ F;  5AEL A;  3LEE A;  5I1U A;  2E8X A;  3PYA A;  3VJC A;  1N1Z A;  4JZB A;  1DI1 A;  5A0J A;  5B0L A;  4NFI F;  4DWG A;  3CKE A;  4NFK F;  4MC8 A;  1YHK A;  2ONH A;  4MC0 A;  4GAX A;  2RAH A;  3LOM A;  1VG4 A;  3B7L A;  3WE9 A;  4KK2 A;  3PH7 A;  5IK0 A;  4KPD A;  1YYR A;  3N1W F;  3VJ9 A;  4DWB A;  5B0K A;  1KIZ A;  4FJQ A;  1FPS A;  5EAU A;  5CG6 A;  4N9U A;  2E92 A;  3IBA A;  3S9V A;  3TFN A;  1N22 A;  3KRO B;  2F8C F;  3WSB A;  4E9Z A;  3N3L F;  2OPM A;  4LFE A;  4KVI A;  1N23 A;  4MC3 A;  4LFG A;  3BNY A;  2ZEU A;  4NKF A;  5B0M A;  3SDR A;  5ERO A;  1N21 A;  1WL0 A;  4KKM A;  2Q9Z A;  4L2X F;  5ILY A;  5JA0 F;  3WCE A;  2PS5 A;  2QIS A;  3ICM A;  1UBY A;  5E8K A;  3EGT A;  2Z50 A;  2Z7H A;  3OAC B;  3ICN A;  4DEM F;  1YYT A;  3WEI A;  3DYG A;  2ZCQ A;  3RMG A;  5A0I A;  3ZMB A;  3LGK A;  5B0J A;  4JZX A;  4OKZ A;  2ONG A;  5AYP A;  2E8U A;  1JFG A;  1UBW A;  4H5E F;  5ILH A;  3VJD A;  5B01 A;  3MZV A;  4RNQ A;  4E1E A;  1HXC A;  1VG3 A;  1YHM A;  1N20 A;  3KRO A;  3LJI A;  3KRP A;  3ICK A;  4LXW A;  4RXC A;  3WCB A;  1YHL A;  4KFA A;  3LSN A;  3APZ A;  5DHI A;  4LZ0 A;  4H5C F;  3DYH A;  5HN9 A;  4KUX A;  4RYP A;  4FP4 A;  1YYU A;  2Z4V A;  5DGN F;  2AEK A;  2E95 A;  2OGD A;  3QKC A;  5JV0 F;  5EAS A;  1WY0 A;  1V4H A;  5IMI A;  1RTR A;  3KB9 A;  4P0W A;  3KRF B;  2PS8 A;  3LG5 A;  4KQ5 A;  2OA6 A;  2F89 F;  2H8O A;  5IMP A;  2ZEV A;  3NF2 A;  4KQS A;  4KVD A;  4OMH A;  3TS7 A;  5B02 A;  4LLT A;  5IMN A;  3SDV A;  5IKH A;  3LDW A;  4LIX A;  2Z4X A;  3N0G A;  5IKA A;  3WCL A;  4OMG A;  4LA5 A;  1N24 A;  1VG6 A;  1YV5 A;  2Z4Z A;  2ZY1 A;  2F94 F;  3M00 A;  5E8H A; 
#chains in the Genus database with same CATH topology
 4UMJ A;  1V4I A;  1WL2 A;  2VF6 A;  1N1B A;  4RXE A;  3P8R A;  3KRC B;  4EA2 A;  3WCA A;  1UBX A;  5ILI A;  3LZ9 A;  3LMD A;  3NRI A;  4LPG F;  3WEG A;  3WSA A;  4NKE A;  4KQU A;  3VJE A;  3KRF A;  3Q30 A;  4GA3 A;  5IN8 A;  3AE0 A;  3S4J A;  5ILJ A;  5C05 A;  3SAE A;  3N5J F;  2PS7 A;  4GP2 A;  2F92 F;  3TC1 A;  3WEJ A;  2O1O A;  3LGZ B;  5JV1 F;  1YQ7 A;  4LOB A;  3WEH A;  4DI5 A;  4JYX A;  5CG5 A;  4ZQ8 A;  3M01 A;  3OAB B;  3G4D A;  3QQV A;  3WEK A;  4LZ3 A;  3V1X A;  5B0I A;  2OPN A;  2E90 A;  1WKZ A;  3WCD A;  4QXS F;  3ASX A;  5HN7 A;  3WCJ A;  5ILK A;  4NUA A;  2Q58 A;  4RXA A;  3KBK A;  5ILZ A;  3KRC A;  5EAT A;  4P0X A;  2F7M F;  3M9U A;  4DXJ A;  4JXY A;  3VJ8 A;  2E8V A;  3N1V F;  5H9D A;  5AHU B;  3WCM A;  2J1O A;  3VJB A;  4EA1 A;  3Q2Q A;  5DJV F;  5A0K A;  4P0V A;  3EFQ A;  1DGP A;  1WL3 A;  3IPI A;  3PKO A;  2ZCS A;  4KPJ A;  3Q2Z A;  4RXD A;  3P41 A;  3AQ0 A;  3ACX A;  4H5D F;  3UCA A;  1HXG A;  3OYR A;  3OAB A;  3CP6 A;  2E94 A;  4Q23 A;  1YYQ A;  3P8L A;  3ZCD A;  3VJA A;  2E93 A;  3OAC A;  4LPH F;  5DJP F;  5DW7 A;  5ERM A;  4GP1 A;  3WCI A;  1JFA A;  4KWD A;  5ILD A;  4E9U A;  3AQC B;  4LLS A;  2F8Z F;  4OGU A;  5IL8 A;  3P5P A;  2AET A;  3V66 A;  3RYE A;  2Z78 A;  5ER8 A;  4LTZ A;  4OKM A;  3W7F A;  3WCG A;  4EA0 A;  3N46 F;  3G4F A;  3PDE A;  5DIQ F;  3N3D A;  3WJK A;  4LFV F;  1KIY A;  5HNA A;  1VG7 A;  2PS4 A;  4XQT F;  1WL1 A;  3DYF A;  3N0F A;  5DGM F;  2F9K F;  4DZW A;  3WC9 A;  5AFX A;  4NG6 A;  5JV2 F;  3N45 F;  3M02 A;  3SDQ A;  3ZL6 A;  3P5R A;  3LK5 A;  2EWG A;  5ERN A;  3ACW A;  3KRA B;  1WMW A;  2E4O A;  3RBM A;  1YYS A;  3NPR A;  2P1C A;  3ACY A;  3SDT A;  3N49 F;  2FOR A;  4HD1 A;  2J1P A;  1HM7 A;  4F62 A;  3EZ3 A;  4WK5 A;  5DHK A;  3V1V A;  5IVG A;  2Z52 A;  5HN8 A;  2Q80 A;  3CC9 A;  4LA6 A;  2Z4Y A;  2AZK A;  4LZC A;  4N1Z F;  3WCF A;  3ADZ A;  4F6X A;  1ZW5 A;  2Z4W A;  4QPF A;  3WCC A;  3KRP B;  2FTZ A;  3Q1O A;  5B00 A;  3ID0 A;  4NFJ F;  2AEL A;  5IM1 A;  3M0G A;  4JVJ F;  4F6V A;  5KSX F;  2Z7I A;  3ZMC A;  2ZCR A;  2E8T A;  5E8L A;  2DH4 A;  3WJN A;  5IK9 A;  1EZF A;  4KVW A;  4DHD A;  4PVY F;  3KRA A;  3WCH A;  2PS6 A;  1V4E A;  3LLW A;  1UBV A;  4K10 A;  3WEF A;  3SDU A;  4XQS F;  5B03 A;  1HXA A;  2E8W A;  2I19 A;  2Q9Y A;  3N5H F;  1HM4 A;  3TFP A;  4KVY A;  5DGS F;  2AZL A;  1VG2 A;  1HX9 A;  1RQJ A;  5IL3 A;  3BNX A;  3TFV A;  2J5C A;  2E91 A;  3ZOU A;  3LVS A;  3PYB A;  3NPK A;  3AQB B;  2AZJ A;  4JXN A;  4LTV A;  3WJO A;  5DJR F;  1V4J A;  1PS1 A;  4LUU A;  1RQI A;  4XQR F;  1YJ4 A;  3RYW A;  4PVX F;  3MAV A;  5IK6 A;  5DZ2 A;  2ZCO A;  1V4K A;  3ICZ A;  3N6K F;  5JUZ F;  5AEL A;  3LEE A;  5I1U A;  2E8X A;  3PYA A;  3VJC A;  1N1Z A;  4JZB A;  1DI1 A;  5A0J A;  5B0L A;  4NFI F;  4DWG A;  3CKE A;  4NFK F;  4MC8 A;  1YHK A;  2ONH A;  4MC0 A;  4GAX A;  2RAH A;  3LOM A;  1VG4 A;  3B7L A;  3WE9 A;  4KK2 A;  3PH7 A;  5IK0 A;  4KPD A;  1YYR A;  3N1W F;  3VJ9 A;  4DWB A;  5B0K A;  1KIZ A;  4FJQ A;  1FPS A;  5EAU A;  5CG6 A;  4N9U A;  2E92 A;  3IBA A;  3S9V A;  3TFN A;  1N22 A;  3KRO B;  2F8C F;  3WSB A;  4E9Z A;  3N3L F;  2OPM A;  4LFE A;  4KVI A;  1N23 A;  4MC3 A;  4LFG A;  3BNY A;  2ZEU A;  4NKF A;  5B0M A;  3SDR A;  5ERO A;  1N21 A;  1WL0 A;  4KKM A;  2Q9Z A;  4L2X F;  5ILY A;  5JA0 F;  3WCE A;  2PS5 A;  2QIS A;  3ICM A;  1UBY A;  5E8K A;  3EGT A;  2Z50 A;  2Z7H A;  3OAC B;  3ICN A;  4DEM F;  1YYT A;  3WEI A;  3DYG A;  2ZCQ A;  3RMG A;  5A0I A;  3ZMB A;  3LGK A;  5B0J A;  4JZX A;  4OKZ A;  2ONG A;  5AYP A;  2E8U A;  1JFG A;  1UBW A;  4H5E F;  5ILH A;  3VJD A;  5B01 A;  3MZV A;  4RNQ A;  4E1E A;  1HXC A;  1VG3 A;  1YHM A;  1N20 A;  3KRO A;  3LJI A;  3KRP A;  3ICK A;  4LXW A;  4RXC A;  3WCB A;  1YHL A;  4KFA A;  3LSN A;  3APZ A;  5DHI A;  4LZ0 A;  4H5C F;  3DYH A;  5HN9 A;  4KUX A;  4RYP A;  4FP4 A;  1YYU A;  2Z4V A;  5DGN F;  2AEK A;  2E95 A;  2OGD A;  3QKC A;  5JV0 F;  5EAS A;  1WY0 A;  1V4H A;  5IMI A;  1RTR A;  3KB9 A;  4P0W A;  3KRF B;  2PS8 A;  3LG5 A;  4KQ5 A;  2OA6 A;  2F89 F;  2H8O A;  5IMP A;  2ZEV A;  3NF2 A;  4KQS A;  4KVD A;  4OMH A;  3TS7 A;  5B02 A;  4LLT A;  5IMN A;  3SDV A;  5IKH A;  3LDW A;  4LIX A;  2Z4X A;  3N0G A;  5IKA A;  3WCL A;  4OMG A;  4LA5 A;  1N24 A;  1VG6 A;  1YV5 A;  2Z4Z A;  2ZY1 A;  2F94 F;  3M00 A;  5E8H A; 
#chains in the Genus database with same CATH homology
 4UMJ A;  1V4I A;  1WL2 A;  2VF6 A;  1N1B A;  4RXE A;  3P8R A;  3KRC B;  4EA2 A;  3WCA A;  1UBX A;  5ILI A;  3LZ9 A;  3LMD A;  3NRI A;  4LPG F;  3WEG A;  3WSA A;  4NKE A;  4KQU A;  3VJE A;  3KRF A;  3Q30 A;  4GA3 A;  5IN8 A;  3AE0 A;  3S4J A;  5ILJ A;  5C05 A;  3SAE A;  3N5J F;  2PS7 A;  4GP2 A;  2F92 F;  3TC1 A;  3WEJ A;  2O1O A;  3LGZ B;  5JV1 F;  1YQ7 A;  4LOB A;  3WEH A;  4DI5 A;  4JYX A;  5CG5 A;  4ZQ8 A;  3M01 A;  3OAB B;  3G4D A;  3QQV A;  3WEK A;  4LZ3 A;  3V1X A;  5B0I A;  2OPN A;  2E90 A;  1WKZ A;  3WCD A;  4QXS F;  3ASX A;  5HN7 A;  3WCJ A;  5ILK A;  4NUA A;  2Q58 A;  4RXA A;  3KBK A;  5ILZ A;  3KRC A;  5EAT A;  4P0X A;  2F7M F;  3M9U A;  4DXJ A;  4JXY A;  3VJ8 A;  2E8V A;  3N1V F;  5H9D A;  5AHU B;  3WCM A;  2J1O A;  3VJB A;  4EA1 A;  3Q2Q A;  5DJV F;  5A0K A;  4P0V A;  3EFQ A;  1DGP A;  1WL3 A;  3IPI A;  3PKO A;  2ZCS A;  4KPJ A;  3Q2Z A;  4RXD A;  3P41 A;  3AQ0 A;  3ACX A;  4H5D F;  3UCA A;  1HXG A;  3OYR A;  3OAB A;  3CP6 A;  2E94 A;  4Q23 A;  1YYQ A;  3P8L A;  3ZCD A;  3VJA A;  2E93 A;  3OAC A;  4LPH F;  5DJP F;  5DW7 A;  5ERM A;  4GP1 A;  3WCI A;  1JFA A;  4KWD A;  5ILD A;  4E9U A;  3AQC B;  4LLS A;  2F8Z F;  4OGU A;  5IL8 A;  3P5P A;  2AET A;  3V66 A;  3RYE A;  2Z78 A;  5ER8 A;  4LTZ A;  4OKM A;  3W7F A;  3WCG A;  4EA0 A;  3N46 F;  3G4F A;  3PDE A;  5DIQ F;  3N3D A;  3WJK A;  4LFV F;  1KIY A;  5HNA A;  1VG7 A;  2PS4 A;  4XQT F;  1WL1 A;  3DYF A;  3N0F A;  5DGM F;  2F9K F;  4DZW A;  3WC9 A;  5AFX A;  4NG6 A;  5JV2 F;  3N45 F;  3M02 A;  3SDQ A;  3ZL6 A;  3P5R A;  3LK5 A;  2EWG A;  5ERN A;  3ACW A;  3KRA B;  1WMW A;  2E4O A;  3RBM A;  1YYS A;  3NPR A;  2P1C A;  3ACY A;  3SDT A;  3N49 F;  2FOR A;  4HD1 A;  2J1P A;  1HM7 A;  4F62 A;  3EZ3 A;  4WK5 A;  5DHK A;  3V1V A;  5IVG A;  2Z52 A;  5HN8 A;  2Q80 A;  3CC9 A;  4LA6 A;  2Z4Y A;  2AZK A;  4LZC A;  4N1Z F;  3WCF A;  3ADZ A;  4F6X A;  1ZW5 A;  2Z4W A;  4QPF A;  3WCC A;  3KRP B;  2FTZ A;  3Q1O A;  5B00 A;  3ID0 A;  4NFJ F;  2AEL A;  5IM1 A;  3M0G A;  4JVJ F;  4F6V A;  5KSX F;  2Z7I A;  3ZMC A;  2ZCR A;  2E8T A;  5E8L A;  2DH4 A;  3WJN A;  5IK9 A;  1EZF A;  4KVW A;  4DHD A;  4PVY F;  3KRA A;  3WCH A;  2PS6 A;  1V4E A;  3LLW A;  1UBV A;  4K10 A;  3WEF A;  3SDU A;  4XQS F;  5B03 A;  1HXA A;  2E8W A;  2I19 A;  2Q9Y A;  3N5H F;  1HM4 A;  3TFP A;  4KVY A;  5DGS F;  2AZL A;  1VG2 A;  1HX9 A;  1RQJ A;  5IL3 A;  3BNX A;  3TFV A;  2J5C A;  2E91 A;  3ZOU A;  3LVS A;  3PYB A;  3NPK A;  3AQB B;  2AZJ A;  4JXN A;  4LTV A;  3WJO A;  5DJR F;  1V4J A;  1PS1 A;  4LUU A;  1RQI A;  4XQR F;  1YJ4 A;  3RYW A;  4PVX F;  3MAV A;  5IK6 A;  5DZ2 A;  2ZCO A;  1V4K A;  3ICZ A;  3N6K F;  5JUZ F;  5AEL A;  3LEE A;  5I1U A;  2E8X A;  3PYA A;  3VJC A;  1N1Z A;  4JZB A;  1DI1 A;  5A0J A;  5B0L A;  4NFI F;  4DWG A;  3CKE A;  4NFK F;  4MC8 A;  1YHK A;  2ONH A;  4MC0 A;  4GAX A;  2RAH A;  3LOM A;  1VG4 A;  3B7L A;  3WE9 A;  4KK2 A;  3PH7 A;  5IK0 A;  4KPD A;  1YYR A;  3N1W F;  3VJ9 A;  4DWB A;  5B0K A;  1KIZ A;  4FJQ A;  1FPS A;  5EAU A;  5CG6 A;  4N9U A;  2E92 A;  3IBA A;  3S9V A;  3TFN A;  1N22 A;  3KRO B;  2F8C F;  3WSB A;  4E9Z A;  3N3L F;  2OPM A;  4LFE A;  4KVI A;  1N23 A;  4MC3 A;  4LFG A;  3BNY A;  2ZEU A;  4NKF A;  5B0M A;  3SDR A;  5ERO A;  1N21 A;  1WL0 A;  4KKM A;  2Q9Z A;  4L2X F;  5ILY A;  5JA0 F;  3WCE A;  2PS5 A;  2QIS A;  3ICM A;  1UBY A;  5E8K A;  3EGT A;  2Z50 A;  2Z7H A;  3OAC B;  3ICN A;  4DEM F;  1YYT A;  3WEI A;  3DYG A;  2ZCQ A;  3RMG A;  5A0I A;  3ZMB A;  3LGK A;  5B0J A;  4JZX A;  4OKZ A;  2ONG A;  5AYP A;  2E8U A;  1JFG A;  1UBW A;  4H5E F;  5ILH A;  3VJD A;  5B01 A;  3MZV A;  4RNQ A;  4E1E A;  1HXC A;  1VG3 A;  1YHM A;  1N20 A;  3KRO A;  3LJI A;  3KRP A;  3ICK A;  4LXW A;  4RXC A;  3WCB A;  1YHL A;  4KFA A;  3LSN A;  3APZ A;  5DHI A;  4LZ0 A;  4H5C F;  3DYH A;  5HN9 A;  4KUX A;  4RYP A;  4FP4 A;  1YYU A;  2Z4V A;  5DGN F;  2AEK A;  2E95 A;  2OGD A;  3QKC A;  5JV0 F;  5EAS A;  1WY0 A;  1V4H A;  5IMI A;  1RTR A;  3KB9 A;  4P0W A;  3KRF B;  2PS8 A;  3LG5 A;  4KQ5 A;  2OA6 A;  2F89 F;  2H8O A;  5IMP A;  2ZEV A;  3NF2 A;  4KQS A;  4KVD A;  4OMH A;  3TS7 A;  5B02 A;  4LLT A;  5IMN A;  3SDV A;  5IKH A;  3LDW A;  4LIX A;  2Z4X A;  3N0G A;  5IKA A;  3WCL A;  4OMG A;  4LA5 A;  1N24 A;  1VG6 A;  1YV5 A;  2Z4Z A;  2ZY1 A;  2F94 F;  3M00 A;  5E8H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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